Amino acid dipepetide frequency for Abras virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.214AlaAla: 3.214 ± 0.994
1.483AlaCys: 1.483 ± 0.451
2.719AlaAsp: 2.719 ± 0.938
1.978AlaGlu: 1.978 ± 0.647
3.214AlaPhe: 3.214 ± 0.681
1.236AlaGly: 1.236 ± 0.851
0.494AlaHis: 0.494 ± 0.487
3.956AlaIle: 3.956 ± 0.511
3.214AlaLys: 3.214 ± 1.538
4.944AlaLeu: 4.944 ± 1.592
1.236AlaMet: 1.236 ± 0.973
3.461AlaAsn: 3.461 ± 1.313
1.483AlaPro: 1.483 ± 0.423
1.978AlaGln: 1.978 ± 0.324
2.967AlaArg: 2.967 ± 1.338
2.225AlaSer: 2.225 ± 0.804
3.461AlaThr: 3.461 ± 2.008
1.731AlaVal: 1.731 ± 0.432
0.247AlaTrp: 0.247 ± 0.161
2.225AlaTyr: 2.225 ± 0.526
0.0AlaXaa: 0.0 ± 0.0
Cys
1.483CysAla: 1.483 ± 0.359
0.247CysCys: 0.247 ± 0.161
0.742CysAsp: 0.742 ± 0.194
1.236CysGlu: 1.236 ± 0.851
1.731CysPhe: 1.731 ± 0.657
2.967CysGly: 2.967 ± 1.486
1.236CysHis: 1.236 ± 0.44
2.719CysIle: 2.719 ± 0.916
2.967CysLys: 2.967 ± 1.486
1.978CysLeu: 1.978 ± 0.966
0.494CysMet: 0.494 ± 0.15
1.978CysAsn: 1.978 ± 0.882
0.742CysPro: 0.742 ± 0.372
1.236CysGln: 1.236 ± 0.512
0.989CysArg: 0.989 ± 0.301
1.731CysSer: 1.731 ± 0.98
2.225CysThr: 2.225 ± 1.115
1.731CysVal: 1.731 ± 1.337
0.247CysTrp: 0.247 ± 0.161
1.236CysTyr: 1.236 ± 0.851
0.0CysXaa: 0.0 ± 0.0
Asp
1.236AspAla: 1.236 ± 0.539
1.483AspCys: 1.483 ± 0.743
2.967AspAsp: 2.967 ± 0.369
3.214AspGlu: 3.214 ± 0.891
4.697AspPhe: 4.697 ± 1.39
2.472AspGly: 2.472 ± 1.0
0.494AspHis: 0.494 ± 0.487
5.192AspIle: 5.192 ± 0.897
3.214AspLys: 3.214 ± 0.33
5.933AspLeu: 5.933 ± 1.061
1.978AspMet: 1.978 ± 1.22
2.719AspAsn: 2.719 ± 0.733
2.472AspPro: 2.472 ± 0.699
1.731AspGln: 1.731 ± 0.655
2.719AspArg: 2.719 ± 1.099
1.731AspSer: 1.731 ± 0.432
2.225AspThr: 2.225 ± 0.526
2.225AspVal: 2.225 ± 0.583
1.236AspTrp: 1.236 ± 1.098
3.708AspTyr: 3.708 ± 0.924
0.0AspXaa: 0.0 ± 0.0
Glu
3.956GluAla: 3.956 ± 1.604
1.731GluCys: 1.731 ± 1.337
3.461GluAsp: 3.461 ± 1.978
3.956GluGlu: 3.956 ± 1.03
5.439GluPhe: 5.439 ± 3.179
2.472GluGly: 2.472 ± 0.311
1.236GluHis: 1.236 ± 0.851
6.428GluIle: 6.428 ± 1.108
4.944GluLys: 4.944 ± 1.397
6.428GluLeu: 6.428 ± 0.516
2.719GluMet: 2.719 ± 1.152
3.708GluAsn: 3.708 ± 0.503
1.731GluPro: 1.731 ± 0.997
2.225GluGln: 2.225 ± 0.583
3.461GluArg: 3.461 ± 1.215
3.708GluSer: 3.708 ± 1.029
3.956GluThr: 3.956 ± 1.051
5.439GluVal: 5.439 ± 1.889
0.494GluTrp: 0.494 ± 0.681
2.967GluTyr: 2.967 ± 0.215
0.0GluXaa: 0.0 ± 0.0
Phe
0.989PheAla: 0.989 ± 0.546
1.978PheCys: 1.978 ± 0.943
3.461PheAsp: 3.461 ± 1.053
4.203PheGlu: 4.203 ± 0.426
2.967PhePhe: 2.967 ± 0.937
2.225PheGly: 2.225 ± 1.115
0.989PheHis: 0.989 ± 0.301
3.708PheIle: 3.708 ± 1.249
5.439PheLys: 5.439 ± 1.551
5.686PheLeu: 5.686 ± 2.874
1.731PheMet: 1.731 ± 0.45
3.956PheAsn: 3.956 ± 0.511
0.989PhePro: 0.989 ± 0.721
0.989PheGln: 0.989 ± 1.053
1.731PheArg: 1.731 ± 0.4
4.45PheSer: 4.45 ± 1.774
3.708PheThr: 3.708 ± 0.924
1.978PheVal: 1.978 ± 0.759
0.742PheTrp: 0.742 ± 0.483
3.214PheTyr: 3.214 ± 1.176
0.0PheXaa: 0.0 ± 0.0
Gly
1.978GlyAla: 1.978 ± 1.221
2.225GlyCys: 2.225 ± 1.115
4.203GlyAsp: 4.203 ± 1.351
3.214GlyGlu: 3.214 ± 1.311
1.483GlyPhe: 1.483 ± 1.198
0.742GlyGly: 0.742 ± 0.74
0.494GlyHis: 0.494 ± 0.487
3.461GlyIle: 3.461 ± 1.602
2.472GlyLys: 2.472 ± 0.817
2.967GlyLeu: 2.967 ± 0.749
0.742GlyMet: 0.742 ± 0.731
3.214GlyAsn: 3.214 ± 0.688
0.742GlyPro: 0.742 ± 0.372
0.989GlyGln: 0.989 ± 0.644
2.472GlyArg: 2.472 ± 1.024
3.214GlySer: 3.214 ± 2.268
2.472GlyThr: 2.472 ± 1.337
1.731GlyVal: 1.731 ± 0.657
0.494GlyTrp: 0.494 ± 0.15
1.236GlyTyr: 1.236 ± 0.512
0.0GlyXaa: 0.0 ± 0.0
His
0.742HisAla: 0.742 ± 0.731
0.742HisCys: 0.742 ± 0.691
0.742HisAsp: 0.742 ± 0.372
1.731HisGlu: 1.731 ± 0.98
0.989HisPhe: 0.989 ± 0.323
1.236HisGly: 1.236 ± 0.539
0.494HisHis: 0.494 ± 0.15
1.483HisIle: 1.483 ± 0.627
1.236HisLys: 1.236 ± 0.472
0.989HisLeu: 0.989 ± 0.644
0.742HisMet: 0.742 ± 0.372
1.978HisAsn: 1.978 ± 0.759
0.742HisPro: 0.742 ± 0.372
0.0HisGln: 0.0 ± 0.0
0.494HisArg: 0.494 ± 0.686
2.719HisSer: 2.719 ± 0.763
1.731HisThr: 1.731 ± 0.657
1.483HisVal: 1.483 ± 0.388
0.247HisTrp: 0.247 ± 0.161
0.494HisTyr: 0.494 ± 0.15
0.0HisXaa: 0.0 ± 0.0
Ile
4.45IleAla: 4.45 ± 1.464
2.225IleCys: 2.225 ± 1.461
2.967IleAsp: 2.967 ± 1.297
6.922IleGlu: 6.922 ± 1.72
3.461IlePhe: 3.461 ± 1.053
3.708IleGly: 3.708 ± 0.566
1.483IleHis: 1.483 ± 0.627
5.686IleIle: 5.686 ± 0.914
9.394IleLys: 9.394 ± 0.95
8.9IleLeu: 8.9 ± 2.247
1.483IleMet: 1.483 ± 0.388
3.461IleAsn: 3.461 ± 0.473
2.719IlePro: 2.719 ± 0.733
3.214IleGln: 3.214 ± 1.1
2.967IleArg: 2.967 ± 0.749
8.158IleSer: 8.158 ± 0.739
3.708IleThr: 3.708 ± 1.234
3.708IleVal: 3.708 ± 0.621
0.494IleTrp: 0.494 ± 0.322
3.708IleTyr: 3.708 ± 0.824
0.0IleXaa: 0.0 ± 0.0
Lys
2.967LysAla: 2.967 ± 0.215
2.472LysCys: 2.472 ± 1.351
4.944LysAsp: 4.944 ± 1.504
7.911LysGlu: 7.911 ± 0.282
4.203LysPhe: 4.203 ± 1.687
4.203LysGly: 4.203 ± 0.426
3.708LysHis: 3.708 ± 0.624
4.203LysIle: 4.203 ± 1.439
4.697LysLys: 4.697 ± 0.68
9.147LysLeu: 9.147 ± 0.836
3.956LysMet: 3.956 ± 0.985
2.719LysAsn: 2.719 ± 0.952
2.967LysPro: 2.967 ± 1.508
1.483LysGln: 1.483 ± 0.627
1.731LysArg: 1.731 ± 0.713
4.697LysSer: 4.697 ± 1.327
5.439LysThr: 5.439 ± 0.686
4.45LysVal: 4.45 ± 1.498
0.989LysTrp: 0.989 ± 0.546
2.967LysTyr: 2.967 ± 0.777
0.0LysXaa: 0.0 ± 0.0
Leu
4.203LeuAla: 4.203 ± 0.698
2.472LeuCys: 2.472 ± 0.88
5.686LeuAsp: 5.686 ± 1.717
6.428LeuGlu: 6.428 ± 0.939
5.192LeuPhe: 5.192 ± 1.332
0.989LeuGly: 0.989 ± 0.546
1.483LeuHis: 1.483 ± 0.965
5.686LeuIle: 5.686 ± 1.453
9.147LeuLys: 9.147 ± 2.87
9.642LeuLeu: 9.642 ± 1.144
2.225LeuMet: 2.225 ± 0.804
4.944LeuAsn: 4.944 ± 0.935
4.697LeuPro: 4.697 ± 0.932
2.719LeuGln: 2.719 ± 1.121
5.686LeuArg: 5.686 ± 0.954
8.653LeuSer: 8.653 ± 1.816
6.922LeuThr: 6.922 ± 1.731
4.45LeuVal: 4.45 ± 0.748
0.247LeuTrp: 0.247 ± 0.161
2.719LeuTyr: 2.719 ± 0.83
0.0LeuXaa: 0.0 ± 0.0
Met
1.978MetAla: 1.978 ± 0.647
0.742MetCys: 0.742 ± 0.372
1.731MetAsp: 1.731 ± 0.444
2.967MetGlu: 2.967 ± 1.814
0.989MetPhe: 0.989 ± 0.546
1.236MetGly: 1.236 ± 0.512
0.247MetHis: 0.247 ± 0.244
3.214MetIle: 3.214 ± 0.881
1.483MetLys: 1.483 ± 0.451
2.472MetLeu: 2.472 ± 0.945
0.989MetMet: 0.989 ± 0.301
1.236MetAsn: 1.236 ± 0.472
1.236MetPro: 1.236 ± 0.512
1.236MetGln: 1.236 ± 0.5
1.483MetArg: 1.483 ± 1.365
2.967MetSer: 2.967 ± 0.215
1.483MetThr: 1.483 ± 0.451
2.719MetVal: 2.719 ± 0.682
0.0MetTrp: 0.0 ± 0.0
0.494MetTyr: 0.494 ± 0.15
0.0MetXaa: 0.0 ± 0.0
Asn
3.708AsnAla: 3.708 ± 0.971
1.978AsnCys: 1.978 ± 0.492
4.203AsnAsp: 4.203 ± 0.937
3.461AsnGlu: 3.461 ± 0.888
1.236AsnPhe: 1.236 ± 1.004
1.483AsnGly: 1.483 ± 1.094
1.978AsnHis: 1.978 ± 0.439
4.203AsnIle: 4.203 ± 1.726
5.439AsnLys: 5.439 ± 1.237
4.45AsnLeu: 4.45 ± 0.87
2.472AsnMet: 2.472 ± 0.752
2.719AsnAsn: 2.719 ± 0.442
1.978AsnPro: 1.978 ± 1.093
1.483AsnGln: 1.483 ± 0.627
1.731AsnArg: 1.731 ± 0.444
3.708AsnSer: 3.708 ± 0.806
2.967AsnThr: 2.967 ± 0.369
0.989AsnVal: 0.989 ± 0.61
0.742AsnTrp: 0.742 ± 0.194
1.731AsnTyr: 1.731 ± 0.785
0.0AsnXaa: 0.0 ± 0.0
Pro
2.225ProAla: 2.225 ± 0.274
0.0ProCys: 0.0 ± 0.0
2.225ProAsp: 2.225 ± 0.583
2.719ProGlu: 2.719 ± 1.152
1.978ProPhe: 1.978 ± 1.22
2.225ProGly: 2.225 ± 1.803
0.742ProHis: 0.742 ± 0.372
3.461ProIle: 3.461 ± 0.392
2.967ProLys: 2.967 ± 0.369
2.472ProLeu: 2.472 ± 1.514
0.494ProMet: 0.494 ± 0.534
0.742ProAsn: 0.742 ± 0.483
0.247ProPro: 0.247 ± 0.161
0.494ProGln: 0.494 ± 0.534
1.978ProArg: 1.978 ± 1.093
1.978ProSer: 1.978 ± 0.943
3.708ProThr: 3.708 ± 0.549
1.483ProVal: 1.483 ± 0.451
0.494ProTrp: 0.494 ± 0.322
1.236ProTyr: 1.236 ± 0.308
0.0ProXaa: 0.0 ± 0.0
Gln
2.719GlnAla: 2.719 ± 0.187
0.742GlnCys: 0.742 ± 0.194
2.225GlnAsp: 2.225 ± 0.832
2.472GlnGlu: 2.472 ± 1.475
1.236GlnPhe: 1.236 ± 0.472
1.731GlnGly: 1.731 ± 0.713
0.742GlnHis: 0.742 ± 0.194
2.719GlnIle: 2.719 ± 0.83
2.472GlnLys: 2.472 ± 0.974
2.967GlnLeu: 2.967 ± 0.91
1.236GlnMet: 1.236 ± 0.308
1.236GlnAsn: 1.236 ± 0.707
0.742GlnPro: 0.742 ± 0.194
1.483GlnGln: 1.483 ± 2.268
0.989GlnArg: 0.989 ± 0.644
0.989GlnSer: 0.989 ± 0.323
2.472GlnThr: 2.472 ± 0.351
0.989GlnVal: 0.989 ± 0.429
0.0GlnTrp: 0.0 ± 0.0
1.236GlnTyr: 1.236 ± 0.539
0.0GlnXaa: 0.0 ± 0.0
Arg
1.978ArgAla: 1.978 ± 0.344
1.483ArgCys: 1.483 ± 0.451
2.967ArgAsp: 2.967 ± 0.215
2.967ArgGlu: 2.967 ± 0.215
2.719ArgPhe: 2.719 ± 0.442
0.989ArgGly: 0.989 ± 0.61
1.236ArgHis: 1.236 ± 0.472
5.686ArgIle: 5.686 ± 1.258
3.214ArgLys: 3.214 ± 0.72
4.45ArgLeu: 4.45 ± 1.783
0.742ArgMet: 0.742 ± 0.286
2.719ArgAsn: 2.719 ± 1.099
0.989ArgPro: 0.989 ± 0.862
1.731ArgGln: 1.731 ± 0.432
3.214ArgArg: 3.214 ± 1.763
1.731ArgSer: 1.731 ± 1.126
1.731ArgThr: 1.731 ± 0.881
3.214ArgVal: 3.214 ± 2.328
0.0ArgTrp: 0.0 ± 0.0
0.989ArgTyr: 0.989 ± 0.323
0.0ArgXaa: 0.0 ± 0.0
Ser
2.967SerAla: 2.967 ± 0.544
2.472SerCys: 2.472 ± 1.703
2.967SerAsp: 2.967 ± 0.97
4.45SerGlu: 4.45 ± 1.095
4.944SerPhe: 4.944 ± 1.221
1.978SerGly: 1.978 ± 0.559
0.742SerHis: 0.742 ± 0.483
7.169SerIle: 7.169 ± 1.84
6.18SerLys: 6.18 ± 1.211
9.147SerLeu: 9.147 ± 3.07
2.225SerMet: 2.225 ± 0.495
2.472SerAsn: 2.472 ± 0.96
2.967SerPro: 2.967 ± 0.304
1.978SerGln: 1.978 ± 0.647
2.472SerArg: 2.472 ± 0.276
3.956SerSer: 3.956 ± 0.787
4.203SerThr: 4.203 ± 0.725
3.956SerVal: 3.956 ± 0.689
0.494SerTrp: 0.494 ± 0.322
2.472SerTyr: 2.472 ± 0.752
0.0SerXaa: 0.0 ± 0.0
Thr
2.967ThrAla: 2.967 ± 0.544
1.978ThrCys: 1.978 ± 1.336
3.214ThrAsp: 3.214 ± 0.518
3.461ThrGlu: 3.461 ± 0.738
2.967ThrPhe: 2.967 ± 0.578
2.967ThrGly: 2.967 ± 1.517
0.989ThrHis: 0.989 ± 0.323
5.933ThrIle: 5.933 ± 1.966
5.439ThrLys: 5.439 ± 0.622
3.461ThrLeu: 3.461 ± 1.204
1.731ThrMet: 1.731 ± 0.785
3.956ThrAsn: 3.956 ± 0.547
3.214ThrPro: 3.214 ± 1.051
2.472ThrGln: 2.472 ± 1.384
2.967ThrArg: 2.967 ± 0.91
5.439ThrSer: 5.439 ± 0.69
4.697ThrThr: 4.697 ± 0.95
1.731ThrVal: 1.731 ± 0.98
0.989ThrTrp: 0.989 ± 0.61
2.719ThrTyr: 2.719 ± 0.733
0.0ThrXaa: 0.0 ± 0.0
Val
2.225ValAla: 2.225 ± 1.104
1.978ValCys: 1.978 ± 1.22
1.236ValAsp: 1.236 ± 0.308
3.708ValGlu: 3.708 ± 0.686
3.956ValPhe: 3.956 ± 0.284
2.719ValGly: 2.719 ± 0.733
1.236ValHis: 1.236 ± 0.472
2.967ValIle: 2.967 ± 1.168
1.483ValLys: 1.483 ± 0.627
4.697ValLeu: 4.697 ± 1.217
2.225ValMet: 2.225 ± 1.156
2.472ValAsn: 2.472 ± 0.966
1.483ValPro: 1.483 ± 0.388
1.483ValGln: 1.483 ± 0.578
2.472ValArg: 2.472 ± 0.693
4.944ValSer: 4.944 ± 1.319
2.719ValThr: 2.719 ± 0.786
1.978ValVal: 1.978 ± 0.904
0.494ValTrp: 0.494 ± 0.487
2.472ValTyr: 2.472 ± 1.024
0.0ValXaa: 0.0 ± 0.0
Trp
0.742TrpAla: 0.742 ± 1.872
0.0TrpCys: 0.0 ± 0.0
0.247TrpAsp: 0.247 ± 0.161
0.247TrpGlu: 0.247 ± 0.161
0.494TrpPhe: 0.494 ± 0.15
0.989TrpGly: 0.989 ± 0.61
0.0TrpHis: 0.0 ± 0.0
0.247TrpIle: 0.247 ± 0.161
0.247TrpLys: 0.247 ± 0.161
0.989TrpLeu: 0.989 ± 0.301
0.0TrpMet: 0.0 ± 0.0
0.494TrpAsn: 0.494 ± 0.322
0.0TrpPro: 0.0 ± 0.0
0.989TrpGln: 0.989 ± 0.644
0.247TrpArg: 0.247 ± 0.716
1.483TrpSer: 1.483 ± 0.627
0.247TrpThr: 0.247 ± 0.161
0.494TrpVal: 0.494 ± 0.322
0.0TrpTrp: 0.0 ± 0.0
0.742TrpTyr: 0.742 ± 0.194
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.742TyrAla: 0.742 ± 0.731
1.483TyrCys: 1.483 ± 1.094
0.742TyrAsp: 0.742 ± 0.194
3.214TyrGlu: 3.214 ± 0.881
1.236TyrPhe: 1.236 ± 0.805
1.978TyrGly: 1.978 ± 0.324
0.989TyrHis: 0.989 ± 0.301
4.697TyrIle: 4.697 ± 1.327
4.203TyrLys: 4.203 ± 1.679
2.472TyrLeu: 2.472 ± 1.298
1.236TyrMet: 1.236 ± 0.308
2.472TyrAsn: 2.472 ± 0.699
1.731TyrPro: 1.731 ± 0.432
1.483TyrGln: 1.483 ± 0.627
2.225TyrArg: 2.225 ± 1.512
1.731TyrSer: 1.731 ± 0.509
3.214TyrThr: 3.214 ± 1.412
2.472TyrVal: 2.472 ± 1.024
0.247TyrTrp: 0.247 ± 0.161
1.483TyrTyr: 1.483 ± 0.451
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4046 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski