Amino acid dipepetide frequency for Sathuvachari virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.187AlaAla: 3.187 ± 1.153
0.671AlaCys: 0.671 ± 0.389
2.181AlaAsp: 2.181 ± 1.324
5.368AlaGlu: 5.368 ± 0.898
2.684AlaPhe: 2.684 ± 0.647
3.858AlaGly: 3.858 ± 0.675
1.007AlaHis: 1.007 ± 0.476
4.026AlaIle: 4.026 ± 0.838
3.02AlaLys: 3.02 ± 0.703
6.375AlaLeu: 6.375 ± 1.015
3.691AlaMet: 3.691 ± 0.85
1.342AlaAsn: 1.342 ± 0.382
2.516AlaPro: 2.516 ± 0.831
1.51AlaGln: 1.51 ± 0.685
5.536AlaArg: 5.536 ± 0.756
4.026AlaSer: 4.026 ± 0.832
3.691AlaThr: 3.691 ± 0.818
4.362AlaVal: 4.362 ± 0.807
0.671AlaTrp: 0.671 ± 0.259
2.684AlaTyr: 2.684 ± 0.659
0.0AlaXaa: 0.0 ± 0.0
Cys
1.174CysAla: 1.174 ± 0.391
0.0CysCys: 0.0 ± 0.0
0.336CysAsp: 0.336 ± 0.229
1.51CysGlu: 1.51 ± 0.438
0.336CysPhe: 0.336 ± 0.299
0.503CysGly: 0.503 ± 0.186
0.336CysHis: 0.336 ± 0.173
0.671CysIle: 0.671 ± 0.278
0.671CysLys: 0.671 ± 0.214
1.342CysLeu: 1.342 ± 0.492
0.168CysMet: 0.168 ± 0.179
0.168CysAsn: 0.168 ± 0.184
0.336CysPro: 0.336 ± 0.214
0.336CysGln: 0.336 ± 0.194
1.51CysArg: 1.51 ± 0.325
0.336CysSer: 0.336 ± 0.209
1.174CysThr: 1.174 ± 0.582
1.174CysVal: 1.174 ± 0.281
0.336CysTrp: 0.336 ± 0.258
1.007CysTyr: 1.007 ± 0.666
0.0CysXaa: 0.0 ± 0.0
Asp
3.858AspAla: 3.858 ± 0.527
0.503AspCys: 0.503 ± 0.31
3.187AspAsp: 3.187 ± 0.602
6.207AspGlu: 6.207 ± 0.817
2.013AspPhe: 2.013 ± 0.443
4.194AspGly: 4.194 ± 0.739
0.503AspHis: 0.503 ± 0.32
2.181AspIle: 2.181 ± 0.844
2.684AspLys: 2.684 ± 0.497
4.865AspLeu: 4.865 ± 0.911
1.845AspMet: 1.845 ± 0.275
1.845AspAsn: 1.845 ± 0.875
3.02AspPro: 3.02 ± 0.683
1.342AspGln: 1.342 ± 0.509
3.691AspArg: 3.691 ± 0.753
2.684AspSer: 2.684 ± 0.849
2.349AspThr: 2.349 ± 0.519
7.046AspVal: 7.046 ± 0.923
0.168AspTrp: 0.168 ± 0.129
1.678AspTyr: 1.678 ± 0.408
0.0AspXaa: 0.0 ± 0.0
Glu
4.194GluAla: 4.194 ± 0.567
1.007GluCys: 1.007 ± 0.421
3.523GluAsp: 3.523 ± 0.637
5.2GluGlu: 5.2 ± 1.286
2.516GluPhe: 2.516 ± 0.753
3.355GluGly: 3.355 ± 0.618
1.845GluHis: 1.845 ± 0.455
3.355GluIle: 3.355 ± 0.535
6.878GluLys: 6.878 ± 1.191
5.2GluLeu: 5.2 ± 0.705
4.026GluMet: 4.026 ± 1.319
2.684GluAsn: 2.684 ± 0.674
2.013GluPro: 2.013 ± 0.637
2.684GluGln: 2.684 ± 0.648
5.2GluArg: 5.2 ± 1.037
4.529GluSer: 4.529 ± 0.877
3.858GluThr: 3.858 ± 0.827
7.717GluVal: 7.717 ± 1.154
1.342GluTrp: 1.342 ± 0.883
1.845GluTyr: 1.845 ± 0.631
0.0GluXaa: 0.0 ± 0.0
Phe
2.013PheAla: 2.013 ± 0.469
0.839PheCys: 0.839 ± 0.304
2.349PheAsp: 2.349 ± 0.68
2.181PheGlu: 2.181 ± 0.646
2.013PhePhe: 2.013 ± 0.772
1.845PheGly: 1.845 ± 0.471
1.174PheHis: 1.174 ± 0.405
1.51PheIle: 1.51 ± 0.493
2.013PheLys: 2.013 ± 0.355
4.529PheLeu: 4.529 ± 0.642
1.007PheMet: 1.007 ± 0.407
1.51PheAsn: 1.51 ± 0.422
0.839PhePro: 0.839 ± 0.178
2.349PheGln: 2.349 ± 0.558
1.678PheArg: 1.678 ± 0.466
4.026PheSer: 4.026 ± 0.892
2.349PheThr: 2.349 ± 0.796
2.181PheVal: 2.181 ± 0.749
0.0PheTrp: 0.0 ± 0.0
1.678PheTyr: 1.678 ± 0.372
0.0PheXaa: 0.0 ± 0.0
Gly
4.865GlyAla: 4.865 ± 0.925
0.839GlyCys: 0.839 ± 0.234
6.207GlyAsp: 6.207 ± 1.104
2.516GlyGlu: 2.516 ± 0.511
1.845GlyPhe: 1.845 ± 0.582
2.852GlyGly: 2.852 ± 0.725
2.181GlyHis: 2.181 ± 0.412
3.691GlyIle: 3.691 ± 1.064
4.194GlyLys: 4.194 ± 0.79
5.033GlyLeu: 5.033 ± 0.576
1.678GlyMet: 1.678 ± 0.462
2.013GlyAsn: 2.013 ± 0.526
1.845GlyPro: 1.845 ± 0.484
2.013GlyGln: 2.013 ± 0.94
3.858GlyArg: 3.858 ± 0.751
3.187GlySer: 3.187 ± 0.518
2.516GlyThr: 2.516 ± 0.722
4.865GlyVal: 4.865 ± 0.52
0.839GlyTrp: 0.839 ± 0.234
2.349GlyTyr: 2.349 ± 0.971
0.0GlyXaa: 0.0 ± 0.0
His
1.342HisAla: 1.342 ± 0.377
0.336HisCys: 0.336 ± 0.204
0.839HisAsp: 0.839 ± 0.388
2.013HisGlu: 2.013 ± 0.433
1.342HisPhe: 1.342 ± 0.483
1.845HisGly: 1.845 ± 0.61
0.503HisHis: 0.503 ± 0.262
2.013HisIle: 2.013 ± 0.729
1.174HisLys: 1.174 ± 0.426
1.342HisLeu: 1.342 ± 0.467
1.007HisMet: 1.007 ± 0.373
1.342HisAsn: 1.342 ± 0.372
1.174HisPro: 1.174 ± 0.414
0.336HisGln: 0.336 ± 0.173
1.845HisArg: 1.845 ± 0.885
2.013HisSer: 2.013 ± 0.647
0.839HisThr: 0.839 ± 0.245
2.516HisVal: 2.516 ± 0.826
0.503HisTrp: 0.503 ± 0.274
0.671HisTyr: 0.671 ± 0.317
0.0HisXaa: 0.0 ± 0.0
Ile
3.523IleAla: 3.523 ± 0.709
0.671IleCys: 0.671 ± 0.248
2.852IleAsp: 2.852 ± 0.619
4.529IleGlu: 4.529 ± 0.651
2.852IlePhe: 2.852 ± 0.616
4.362IleGly: 4.362 ± 0.711
1.678IleHis: 1.678 ± 0.374
2.516IleIle: 2.516 ± 0.573
3.187IleLys: 3.187 ± 0.415
6.375IleLeu: 6.375 ± 0.926
2.684IleMet: 2.684 ± 0.687
2.684IleAsn: 2.684 ± 0.419
2.852IlePro: 2.852 ± 0.738
2.516IleGln: 2.516 ± 0.354
4.026IleArg: 4.026 ± 0.63
5.033IleSer: 5.033 ± 0.688
4.362IleThr: 4.362 ± 0.511
1.845IleVal: 1.845 ± 0.477
0.336IleTrp: 0.336 ± 0.204
3.02IleTyr: 3.02 ± 0.775
0.0IleXaa: 0.0 ± 0.0
Lys
2.852LysAla: 2.852 ± 0.828
0.839LysCys: 0.839 ± 0.454
2.349LysAsp: 2.349 ± 0.412
3.523LysGlu: 3.523 ± 1.141
2.852LysPhe: 2.852 ± 0.533
3.355LysGly: 3.355 ± 0.807
1.51LysHis: 1.51 ± 0.494
6.207LysIle: 6.207 ± 1.108
4.865LysLys: 4.865 ± 1.055
5.368LysLeu: 5.368 ± 1.137
1.678LysMet: 1.678 ± 0.846
2.181LysAsn: 2.181 ± 0.47
0.839LysPro: 0.839 ± 0.24
1.678LysGln: 1.678 ± 0.689
3.187LysArg: 3.187 ± 0.517
2.181LysSer: 2.181 ± 0.493
2.852LysThr: 2.852 ± 0.71
4.529LysVal: 4.529 ± 0.992
1.007LysTrp: 1.007 ± 0.431
2.852LysTyr: 2.852 ± 1.062
0.0LysXaa: 0.0 ± 0.0
Leu
6.039LeuAla: 6.039 ± 1.186
2.013LeuCys: 2.013 ± 0.888
5.2LeuAsp: 5.2 ± 1.178
6.207LeuGlu: 6.207 ± 0.939
2.349LeuPhe: 2.349 ± 0.743
3.691LeuGly: 3.691 ± 0.593
2.181LeuHis: 2.181 ± 0.523
5.704LeuIle: 5.704 ± 1.172
5.368LeuLys: 5.368 ± 0.818
7.717LeuLeu: 7.717 ± 1.201
3.02LeuMet: 3.02 ± 0.726
3.187LeuAsn: 3.187 ± 0.636
5.368LeuPro: 5.368 ± 1.275
3.858LeuGln: 3.858 ± 0.352
9.394LeuArg: 9.394 ± 1.542
5.704LeuSer: 5.704 ± 1.291
5.871LeuThr: 5.871 ± 0.881
3.355LeuVal: 3.355 ± 0.527
0.839LeuTrp: 0.839 ± 0.256
3.691LeuTyr: 3.691 ± 0.866
0.0LeuXaa: 0.0 ± 0.0
Met
2.181MetAla: 2.181 ± 0.388
0.503MetCys: 0.503 ± 0.32
1.845MetAsp: 1.845 ± 0.515
1.845MetGlu: 1.845 ± 0.5
1.678MetPhe: 1.678 ± 0.332
1.342MetGly: 1.342 ± 0.3
0.503MetHis: 0.503 ± 0.363
2.181MetIle: 2.181 ± 0.282
2.013MetLys: 2.013 ± 0.385
4.026MetLeu: 4.026 ± 0.814
1.342MetMet: 1.342 ± 0.259
1.51MetAsn: 1.51 ± 0.441
1.342MetPro: 1.342 ± 0.322
2.516MetGln: 2.516 ± 0.592
3.355MetArg: 3.355 ± 0.938
3.02MetSer: 3.02 ± 0.697
1.845MetThr: 1.845 ± 0.61
1.678MetVal: 1.678 ± 0.476
0.503MetTrp: 0.503 ± 0.439
1.678MetTyr: 1.678 ± 0.676
0.0MetXaa: 0.0 ± 0.0
Asn
2.684AsnAla: 2.684 ± 0.762
0.0AsnCys: 0.0 ± 0.0
2.181AsnAsp: 2.181 ± 0.767
3.523AsnGlu: 3.523 ± 0.854
2.349AsnPhe: 2.349 ± 0.409
4.026AsnGly: 4.026 ± 0.655
0.168AsnHis: 0.168 ± 0.15
3.523AsnIle: 3.523 ± 0.733
1.51AsnLys: 1.51 ± 0.471
4.362AsnLeu: 4.362 ± 0.956
0.839AsnMet: 0.839 ± 0.429
1.845AsnAsn: 1.845 ± 0.516
1.174AsnPro: 1.174 ± 0.597
1.678AsnGln: 1.678 ± 0.533
2.013AsnArg: 2.013 ± 0.651
2.181AsnSer: 2.181 ± 0.645
2.349AsnThr: 2.349 ± 0.52
3.355AsnVal: 3.355 ± 0.757
0.336AsnTrp: 0.336 ± 0.227
1.342AsnTyr: 1.342 ± 0.447
0.0AsnXaa: 0.0 ± 0.0
Pro
1.845ProAla: 1.845 ± 0.483
0.168ProCys: 0.168 ± 0.129
2.516ProAsp: 2.516 ± 0.495
2.684ProGlu: 2.684 ± 0.608
1.007ProPhe: 1.007 ± 0.483
1.845ProGly: 1.845 ± 0.352
1.51ProHis: 1.51 ± 0.348
2.516ProIle: 2.516 ± 0.411
2.013ProLys: 2.013 ± 0.656
3.355ProLeu: 3.355 ± 0.309
1.51ProMet: 1.51 ± 0.467
1.51ProAsn: 1.51 ± 0.415
1.342ProPro: 1.342 ± 0.371
2.181ProGln: 2.181 ± 0.726
2.516ProArg: 2.516 ± 0.874
1.174ProSer: 1.174 ± 0.313
1.678ProThr: 1.678 ± 0.435
2.349ProVal: 2.349 ± 0.276
0.503ProTrp: 0.503 ± 0.342
1.174ProTyr: 1.174 ± 0.458
0.168ProXaa: 0.168 ± 0.129
Gln
3.187GlnAla: 3.187 ± 0.6
0.336GlnCys: 0.336 ± 0.299
2.516GlnAsp: 2.516 ± 0.648
3.02GlnGlu: 3.02 ± 0.811
2.013GlnPhe: 2.013 ± 0.418
2.181GlnGly: 2.181 ± 0.9
1.174GlnHis: 1.174 ± 0.42
3.691GlnIle: 3.691 ± 0.503
1.51GlnLys: 1.51 ± 0.571
3.523GlnLeu: 3.523 ± 0.479
1.678GlnMet: 1.678 ± 0.497
2.013GlnAsn: 2.013 ± 0.75
0.671GlnPro: 0.671 ± 0.335
1.678GlnGln: 1.678 ± 0.46
3.02GlnArg: 3.02 ± 0.613
2.181GlnSer: 2.181 ± 0.749
2.349GlnThr: 2.349 ± 0.706
1.342GlnVal: 1.342 ± 0.268
0.503GlnTrp: 0.503 ± 0.369
1.174GlnTyr: 1.174 ± 0.704
0.0GlnXaa: 0.0 ± 0.0
Arg
5.033ArgAla: 5.033 ± 1.29
1.174ArgCys: 1.174 ± 0.567
4.697ArgAsp: 4.697 ± 0.774
6.375ArgGlu: 6.375 ± 0.815
3.02ArgPhe: 3.02 ± 0.829
5.368ArgGly: 5.368 ± 0.661
1.51ArgHis: 1.51 ± 0.519
3.187ArgIle: 3.187 ± 0.825
3.02ArgLys: 3.02 ± 0.707
5.033ArgLeu: 5.033 ± 0.686
2.852ArgMet: 2.852 ± 0.449
4.194ArgAsn: 4.194 ± 0.507
1.678ArgPro: 1.678 ± 0.446
2.852ArgGln: 2.852 ± 0.552
4.529ArgArg: 4.529 ± 0.846
3.858ArgSer: 3.858 ± 0.747
3.02ArgThr: 3.02 ± 0.702
6.375ArgVal: 6.375 ± 0.819
0.671ArgTrp: 0.671 ± 0.316
2.684ArgTyr: 2.684 ± 0.558
0.0ArgXaa: 0.0 ± 0.0
Ser
4.865SerAla: 4.865 ± 1.02
0.671SerCys: 0.671 ± 0.225
3.187SerAsp: 3.187 ± 0.517
5.2SerGlu: 5.2 ± 1.073
2.181SerPhe: 2.181 ± 1.024
2.516SerGly: 2.516 ± 0.616
1.678SerHis: 1.678 ± 0.287
3.355SerIle: 3.355 ± 0.556
3.187SerLys: 3.187 ± 0.784
4.697SerLeu: 4.697 ± 0.861
2.349SerMet: 2.349 ± 0.581
2.684SerAsn: 2.684 ± 0.526
1.342SerPro: 1.342 ± 0.389
2.684SerGln: 2.684 ± 0.533
4.529SerArg: 4.529 ± 0.878
3.523SerSer: 3.523 ± 0.575
4.194SerThr: 4.194 ± 0.596
4.194SerVal: 4.194 ± 1.212
0.671SerTrp: 0.671 ± 0.195
3.858SerTyr: 3.858 ± 0.654
0.0SerXaa: 0.0 ± 0.0
Thr
3.187ThrAla: 3.187 ± 0.71
1.007ThrCys: 1.007 ± 0.457
2.516ThrAsp: 2.516 ± 0.526
3.691ThrGlu: 3.691 ± 0.771
1.678ThrPhe: 1.678 ± 0.486
4.194ThrGly: 4.194 ± 0.483
1.51ThrHis: 1.51 ± 0.293
2.852ThrIle: 2.852 ± 0.527
4.362ThrLys: 4.362 ± 0.95
5.368ThrLeu: 5.368 ± 1.199
1.845ThrMet: 1.845 ± 0.517
2.516ThrAsn: 2.516 ± 0.73
3.355ThrPro: 3.355 ± 0.675
2.684ThrGln: 2.684 ± 0.378
3.02ThrArg: 3.02 ± 1.003
3.691ThrSer: 3.691 ± 0.98
3.355ThrThr: 3.355 ± 0.377
3.187ThrVal: 3.187 ± 0.61
0.336ThrTrp: 0.336 ± 0.18
1.174ThrTyr: 1.174 ± 0.415
0.0ThrXaa: 0.0 ± 0.0
Val
4.194ValAla: 4.194 ± 0.635
0.671ValCys: 0.671 ± 0.223
4.026ValAsp: 4.026 ± 0.862
4.194ValGlu: 4.194 ± 0.969
1.678ValPhe: 1.678 ± 0.5
4.529ValGly: 4.529 ± 1.116
1.845ValHis: 1.845 ± 0.342
5.536ValIle: 5.536 ± 0.922
2.516ValLys: 2.516 ± 0.836
7.381ValLeu: 7.381 ± 0.782
2.181ValMet: 2.181 ± 0.432
3.691ValAsn: 3.691 ± 1.012
2.516ValPro: 2.516 ± 0.557
3.187ValGln: 3.187 ± 1.061
5.368ValArg: 5.368 ± 0.963
4.529ValSer: 4.529 ± 0.555
3.355ValThr: 3.355 ± 0.462
4.697ValVal: 4.697 ± 0.813
1.007ValTrp: 1.007 ± 0.442
3.187ValTyr: 3.187 ± 0.698
0.0ValXaa: 0.0 ± 0.0
Trp
0.336TrpAla: 0.336 ± 0.211
0.168TrpCys: 0.168 ± 0.175
1.174TrpAsp: 1.174 ± 0.328
0.839TrpGlu: 0.839 ± 0.253
0.336TrpPhe: 0.336 ± 0.258
0.336TrpGly: 0.336 ± 0.19
1.007TrpHis: 1.007 ± 0.506
0.839TrpIle: 0.839 ± 0.31
1.174TrpLys: 1.174 ± 0.39
0.839TrpLeu: 0.839 ± 0.337
0.168TrpMet: 0.168 ± 0.15
0.503TrpAsn: 0.503 ± 0.266
0.168TrpPro: 0.168 ± 0.145
0.336TrpGln: 0.336 ± 0.187
0.671TrpArg: 0.671 ± 0.301
0.168TrpSer: 0.168 ± 0.179
0.671TrpThr: 0.671 ± 0.345
0.671TrpVal: 0.671 ± 0.339
0.503TrpTrp: 0.503 ± 0.369
0.336TrpTyr: 0.336 ± 0.227
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.845TyrAla: 1.845 ± 0.493
0.839TyrCys: 0.839 ± 0.298
2.181TyrAsp: 2.181 ± 0.472
2.349TyrGlu: 2.349 ± 0.537
1.342TyrPhe: 1.342 ± 0.346
3.187TyrGly: 3.187 ± 0.452
1.174TyrHis: 1.174 ± 0.362
2.349TyrIle: 2.349 ± 0.588
1.342TyrLys: 1.342 ± 0.454
4.026TyrLeu: 4.026 ± 0.831
1.174TyrMet: 1.174 ± 0.511
2.013TyrAsn: 2.013 ± 0.678
1.174TyrPro: 1.174 ± 0.472
1.342TyrGln: 1.342 ± 0.389
2.181TyrArg: 2.181 ± 0.537
3.523TyrSer: 3.523 ± 0.782
2.852TyrThr: 2.852 ± 0.87
3.02TyrVal: 3.02 ± 0.829
0.168TyrTrp: 0.168 ± 0.175
1.845TyrTyr: 1.845 ± 0.441
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.168XaaCys: 0.168 ± 0.129
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (5962 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski