Amino acid dipepetide frequency for Compostimonas suwonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.236AlaAla: 19.236 ± 0.204
0.59AlaCys: 0.59 ± 0.026
7.687AlaAsp: 7.687 ± 0.098
7.811AlaGlu: 7.811 ± 0.107
3.808AlaPhe: 3.808 ± 0.069
12.219AlaGly: 12.219 ± 0.124
2.277AlaHis: 2.277 ± 0.044
6.012AlaIle: 6.012 ± 0.079
2.484AlaLys: 2.484 ± 0.062
13.32AlaLeu: 13.32 ± 0.136
2.271AlaMet: 2.271 ± 0.052
2.601AlaAsn: 2.601 ± 0.055
6.507AlaPro: 6.507 ± 0.088
3.982AlaGln: 3.982 ± 0.062
8.56AlaArg: 8.56 ± 0.129
8.125AlaSer: 8.125 ± 0.095
7.435AlaThr: 7.435 ± 0.106
11.117AlaVal: 11.117 ± 0.127
1.701AlaTrp: 1.701 ± 0.046
2.238AlaTyr: 2.238 ± 0.048
0.0AlaXaa: 0.0 ± 0.0
Cys
0.606CysAla: 0.606 ± 0.023
0.057CysCys: 0.057 ± 0.007
0.271CysAsp: 0.271 ± 0.017
0.247CysGlu: 0.247 ± 0.017
0.17CysPhe: 0.17 ± 0.012
0.524CysGly: 0.524 ± 0.022
0.097CysHis: 0.097 ± 0.01
0.171CysIle: 0.171 ± 0.013
0.04CysLys: 0.04 ± 0.006
0.432CysLeu: 0.432 ± 0.022
0.067CysMet: 0.067 ± 0.007
0.093CysAsn: 0.093 ± 0.007
0.248CysPro: 0.248 ± 0.017
0.117CysGln: 0.117 ± 0.011
0.282CysArg: 0.282 ± 0.018
0.329CysSer: 0.329 ± 0.02
0.291CysThr: 0.291 ± 0.017
0.442CysVal: 0.442 ± 0.019
0.063CysTrp: 0.063 ± 0.008
0.102CysTyr: 0.102 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
8.481AspAla: 8.481 ± 0.094
0.257AspCys: 0.257 ± 0.017
4.542AspAsp: 4.542 ± 0.077
4.415AspGlu: 4.415 ± 0.066
1.889AspPhe: 1.889 ± 0.042
6.234AspGly: 6.234 ± 0.112
1.219AspHis: 1.219 ± 0.04
2.488AspIle: 2.488 ± 0.048
0.924AspLys: 0.924 ± 0.034
5.555AspLeu: 5.555 ± 0.073
0.772AspMet: 0.772 ± 0.027
1.107AspAsn: 1.107 ± 0.036
4.28AspPro: 4.28 ± 0.074
1.504AspGln: 1.504 ± 0.036
4.016AspArg: 4.016 ± 0.072
3.106AspSer: 3.106 ± 0.058
3.111AspThr: 3.111 ± 0.055
5.077AspVal: 5.077 ± 0.078
0.927AspTrp: 0.927 ± 0.029
1.593AspTyr: 1.593 ± 0.047
0.0AspXaa: 0.0 ± 0.0
Glu
6.715GluAla: 6.715 ± 0.09
0.225GluCys: 0.225 ± 0.014
2.165GluAsp: 2.165 ± 0.052
2.865GluGlu: 2.865 ± 0.071
1.889GluPhe: 1.889 ± 0.041
4.063GluGly: 4.063 ± 0.064
1.419GluHis: 1.419 ± 0.037
2.662GluIle: 2.662 ± 0.053
1.313GluLys: 1.313 ± 0.037
7.245GluLeu: 7.245 ± 0.113
0.884GluMet: 0.884 ± 0.028
1.361GluAsn: 1.361 ± 0.035
3.342GluPro: 3.342 ± 0.061
2.462GluGln: 2.462 ± 0.051
5.022GluArg: 5.022 ± 0.096
3.291GluSer: 3.291 ± 0.058
3.23GluThr: 3.23 ± 0.052
4.326GluVal: 4.326 ± 0.065
0.956GluTrp: 0.956 ± 0.031
1.135GluTyr: 1.135 ± 0.03
0.0GluXaa: 0.0 ± 0.0
Phe
4.216PheAla: 4.216 ± 0.063
0.165PheCys: 0.165 ± 0.012
2.453PheAsp: 2.453 ± 0.048
1.859PheGlu: 1.859 ± 0.041
1.085PhePhe: 1.085 ± 0.035
3.502PheGly: 3.502 ± 0.064
0.521PheHis: 0.521 ± 0.023
1.208PheIle: 1.208 ± 0.033
0.4PheLys: 0.4 ± 0.021
2.844PheLeu: 2.844 ± 0.049
0.407PheMet: 0.407 ± 0.016
0.676PheAsn: 0.676 ± 0.026
1.413PhePro: 1.413 ± 0.037
0.82PheGln: 0.82 ± 0.028
1.81PheArg: 1.81 ± 0.046
1.998PheSer: 1.998 ± 0.046
2.19PheThr: 2.19 ± 0.044
2.944PheVal: 2.944 ± 0.058
0.494PheTrp: 0.494 ± 0.021
0.686PheTyr: 0.686 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
10.655GlyAla: 10.655 ± 0.129
0.542GlyCys: 0.542 ± 0.022
5.347GlyAsp: 5.347 ± 0.091
5.145GlyGlu: 5.145 ± 0.07
3.397GlyPhe: 3.397 ± 0.049
8.107GlyGly: 8.107 ± 0.129
1.769GlyHis: 1.769 ± 0.04
4.998GlyIle: 4.998 ± 0.078
1.945GlyLys: 1.945 ± 0.047
9.028GlyLeu: 9.028 ± 0.104
1.839GlyMet: 1.839 ± 0.042
1.836GlyAsn: 1.836 ± 0.048
3.842GlyPro: 3.842 ± 0.061
2.559GlyGln: 2.559 ± 0.048
6.044GlyArg: 6.044 ± 0.087
6.306GlySer: 6.306 ± 0.11
6.011GlyThr: 6.011 ± 0.122
7.997GlyVal: 7.997 ± 0.098
1.554GlyTrp: 1.554 ± 0.039
2.372GlyTyr: 2.372 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
2.083HisAla: 2.083 ± 0.047
0.111HisCys: 0.111 ± 0.009
1.366HisAsp: 1.366 ± 0.035
1.18HisGlu: 1.18 ± 0.035
0.542HisPhe: 0.542 ± 0.024
1.883HisGly: 1.883 ± 0.038
0.469HisHis: 0.469 ± 0.022
0.687HisIle: 0.687 ± 0.026
0.27HisLys: 0.27 ± 0.016
1.872HisLeu: 1.872 ± 0.045
0.287HisMet: 0.287 ± 0.017
0.405HisAsn: 0.405 ± 0.02
1.395HisPro: 1.395 ± 0.042
0.405HisGln: 0.405 ± 0.019
1.413HisArg: 1.413 ± 0.038
1.105HisSer: 1.105 ± 0.034
1.015HisThr: 1.015 ± 0.031
1.494HisVal: 1.494 ± 0.043
0.273HisTrp: 0.273 ± 0.018
0.467HisTyr: 0.467 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
6.847IleAla: 6.847 ± 0.083
0.232IleCys: 0.232 ± 0.014
3.479IleAsp: 3.479 ± 0.063
2.834IleGlu: 2.834 ± 0.047
1.225IlePhe: 1.225 ± 0.033
4.737IleGly: 4.737 ± 0.068
0.69IleHis: 0.69 ± 0.024
1.783IleIle: 1.783 ± 0.051
0.749IleLys: 0.749 ± 0.028
3.869IleLeu: 3.869 ± 0.067
0.661IleMet: 0.661 ± 0.025
0.993IleAsn: 0.993 ± 0.031
2.599IlePro: 2.599 ± 0.047
1.0IleGln: 1.0 ± 0.034
2.735IleArg: 2.735 ± 0.053
2.379IleSer: 2.379 ± 0.051
2.896IleThr: 2.896 ± 0.049
5.144IleVal: 5.144 ± 0.074
0.533IleTrp: 0.533 ± 0.024
0.804IleTyr: 0.804 ± 0.03
0.0IleXaa: 0.0 ± 0.0
Lys
2.286LysAla: 2.286 ± 0.053
0.049LysCys: 0.049 ± 0.006
1.087LysAsp: 1.087 ± 0.041
0.849LysGlu: 0.849 ± 0.033
0.449LysPhe: 0.449 ± 0.019
1.407LysGly: 1.407 ± 0.037
0.378LysHis: 0.378 ± 0.019
0.857LysIle: 0.857 ± 0.033
0.704LysLys: 0.704 ± 0.035
1.81LysLeu: 1.81 ± 0.041
0.31LysMet: 0.31 ± 0.016
0.538LysAsn: 0.538 ± 0.023
1.198LysPro: 1.198 ± 0.034
0.611LysGln: 0.611 ± 0.021
1.515LysArg: 1.515 ± 0.041
1.05LysSer: 1.05 ± 0.031
1.375LysThr: 1.375 ± 0.04
1.438LysVal: 1.438 ± 0.041
0.238LysTrp: 0.238 ± 0.016
0.42LysTyr: 0.42 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
14.228LeuAla: 14.228 ± 0.134
0.473LeuCys: 0.473 ± 0.02
6.822LeuAsp: 6.822 ± 0.086
5.267LeuGlu: 5.267 ± 0.084
2.939LeuPhe: 2.939 ± 0.056
9.594LeuGly: 9.594 ± 0.111
1.742LeuHis: 1.742 ± 0.042
4.368LeuIle: 4.368 ± 0.084
1.604LeuLys: 1.604 ± 0.043
10.14LeuLeu: 10.14 ± 0.149
1.528LeuMet: 1.528 ± 0.04
1.859LeuAsn: 1.859 ± 0.042
5.492LeuPro: 5.492 ± 0.064
2.392LeuGln: 2.392 ± 0.047
6.765LeuArg: 6.765 ± 0.108
6.354LeuSer: 6.354 ± 0.082
6.261LeuThr: 6.261 ± 0.068
9.709LeuVal: 9.709 ± 0.122
1.296LeuTrp: 1.296 ± 0.034
1.763LeuTyr: 1.763 ± 0.045
0.0LeuXaa: 0.0 ± 0.0
Met
1.897MetAla: 1.897 ± 0.045
0.078MetCys: 0.078 ± 0.008
0.769MetAsp: 0.769 ± 0.03
0.588MetGlu: 0.588 ± 0.021
0.467MetPhe: 0.467 ± 0.019
1.166MetGly: 1.166 ± 0.033
0.312MetHis: 0.312 ± 0.015
0.849MetIle: 0.849 ± 0.032
0.391MetLys: 0.391 ± 0.018
1.739MetLeu: 1.739 ± 0.04
0.273MetMet: 0.273 ± 0.015
0.472MetAsn: 0.472 ± 0.021
1.076MetPro: 1.076 ± 0.029
0.51MetGln: 0.51 ± 0.02
1.232MetArg: 1.232 ± 0.031
1.511MetSer: 1.511 ± 0.036
1.598MetThr: 1.598 ± 0.033
1.217MetVal: 1.217 ± 0.03
0.171MetTrp: 0.171 ± 0.011
0.242MetTyr: 0.242 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.602AsnAla: 2.602 ± 0.055
0.106AsnCys: 0.106 ± 0.01
1.318AsnAsp: 1.318 ± 0.035
1.147AsnGlu: 1.147 ± 0.031
0.67AsnPhe: 0.67 ± 0.026
2.271AsnGly: 2.271 ± 0.063
0.365AsnHis: 0.365 ± 0.019
0.843AsnIle: 0.843 ± 0.031
0.396AsnLys: 0.396 ± 0.022
1.997AsnLeu: 1.997 ± 0.043
0.306AsnMet: 0.306 ± 0.019
0.584AsnAsn: 0.584 ± 0.032
1.752AsnPro: 1.752 ± 0.041
0.58AsnGln: 0.58 ± 0.025
1.348AsnArg: 1.348 ± 0.035
1.187AsnSer: 1.187 ± 0.037
1.381AsnThr: 1.381 ± 0.042
1.766AsnVal: 1.766 ± 0.045
0.35AsnTrp: 0.35 ± 0.017
0.569AsnTyr: 0.569 ± 0.026
0.0AsnXaa: 0.0 ± 0.0
Pro
7.512ProAla: 7.512 ± 0.091
0.185ProCys: 0.185 ± 0.011
3.801ProAsp: 3.801 ± 0.061
3.81ProGlu: 3.81 ± 0.067
1.654ProPhe: 1.654 ± 0.039
5.552ProGly: 5.552 ± 0.085
1.074ProHis: 1.074 ± 0.033
2.219ProIle: 2.219 ± 0.045
0.931ProLys: 0.931 ± 0.036
4.882ProLeu: 4.882 ± 0.068
0.791ProMet: 0.791 ± 0.026
1.184ProAsn: 1.184 ± 0.036
2.543ProPro: 2.543 ± 0.063
1.701ProGln: 1.701 ± 0.043
3.271ProArg: 3.271 ± 0.054
3.553ProSer: 3.553 ± 0.055
3.567ProThr: 3.567 ± 0.068
5.036ProVal: 5.036 ± 0.081
0.873ProTrp: 0.873 ± 0.026
1.092ProTyr: 1.092 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
3.568GlnAla: 3.568 ± 0.061
0.1GlnCys: 0.1 ± 0.01
1.283GlnAsp: 1.283 ± 0.038
1.253GlnGlu: 1.253 ± 0.034
0.893GlnPhe: 0.893 ± 0.028
2.034GlnGly: 2.034 ± 0.043
0.572GlnHis: 0.572 ± 0.021
1.533GlnIle: 1.533 ± 0.04
0.64GlnLys: 0.64 ± 0.02
3.453GlnLeu: 3.453 ± 0.055
0.504GlnMet: 0.504 ± 0.023
0.763GlnAsn: 0.763 ± 0.031
1.701GlnPro: 1.701 ± 0.043
1.202GlnGln: 1.202 ± 0.038
2.155GlnArg: 2.155 ± 0.049
1.748GlnSer: 1.748 ± 0.035
1.82GlnThr: 1.82 ± 0.043
2.094GlnVal: 2.094 ± 0.046
0.495GlnTrp: 0.495 ± 0.024
0.644GlnTyr: 0.644 ± 0.026
0.0GlnXaa: 0.0 ± 0.0
Arg
8.142ArgAla: 8.142 ± 0.111
0.269ArgCys: 0.269 ± 0.015
3.91ArgAsp: 3.91 ± 0.075
4.149ArgGlu: 4.149 ± 0.076
2.348ArgPhe: 2.348 ± 0.046
5.267ArgGly: 5.267 ± 0.076
1.422ArgHis: 1.422 ± 0.042
3.463ArgIle: 3.463 ± 0.059
1.306ArgLys: 1.306 ± 0.039
7.068ArgLeu: 7.068 ± 0.095
1.586ArgMet: 1.586 ± 0.04
1.367ArgAsn: 1.367 ± 0.035
3.479ArgPro: 3.479 ± 0.069
2.016ArgGln: 2.016 ± 0.051
6.048ArgArg: 6.048 ± 0.105
4.281ArgSer: 4.281 ± 0.063
3.973ArgThr: 3.973 ± 0.064
5.612ArgVal: 5.612 ± 0.08
1.032ArgTrp: 1.032 ± 0.031
1.664ArgTyr: 1.664 ± 0.041
0.0ArgXaa: 0.0 ± 0.0
Ser
7.753SerAla: 7.753 ± 0.09
0.281SerCys: 0.281 ± 0.017
3.674SerAsp: 3.674 ± 0.058
3.264SerGlu: 3.264 ± 0.056
2.104SerPhe: 2.104 ± 0.05
6.54SerGly: 6.54 ± 0.089
1.109SerHis: 1.109 ± 0.035
2.944SerIle: 2.944 ± 0.046
1.153SerLys: 1.153 ± 0.036
5.748SerLeu: 5.748 ± 0.07
1.109SerMet: 1.109 ± 0.031
1.399SerAsn: 1.399 ± 0.039
3.51SerPro: 3.51 ± 0.062
1.539SerGln: 1.539 ± 0.038
4.033SerArg: 4.033 ± 0.066
4.353SerSer: 4.353 ± 0.076
4.161SerThr: 4.161 ± 0.067
5.146SerVal: 5.146 ± 0.074
1.077SerTrp: 1.077 ± 0.032
1.591SerTyr: 1.591 ± 0.045
0.0SerXaa: 0.0 ± 0.0
Thr
8.11ThrAla: 8.11 ± 0.118
0.233ThrCys: 0.233 ± 0.014
3.581ThrAsp: 3.581 ± 0.074
3.128ThrGlu: 3.128 ± 0.049
1.846ThrPhe: 1.846 ± 0.043
6.151ThrGly: 6.151 ± 0.082
1.032ThrHis: 1.032 ± 0.029
3.412ThrIle: 3.412 ± 0.06
1.166ThrLys: 1.166 ± 0.037
5.988ThrLeu: 5.988 ± 0.065
0.97ThrMet: 0.97 ± 0.029
1.35ThrAsn: 1.35 ± 0.047
4.335ThrPro: 4.335 ± 0.085
1.599ThrGln: 1.599 ± 0.042
3.793ThrArg: 3.793 ± 0.065
3.884ThrSer: 3.884 ± 0.073
4.391ThrThr: 4.391 ± 0.073
6.409ThrVal: 6.409 ± 0.123
0.79ThrTrp: 0.79 ± 0.029
0.963ThrTyr: 0.963 ± 0.029
0.0ThrXaa: 0.0 ± 0.0
Val
11.176ValAla: 11.176 ± 0.108
0.472ValCys: 0.472 ± 0.019
5.804ValAsp: 5.804 ± 0.074
4.913ValGlu: 4.913 ± 0.078
2.98ValPhe: 2.98 ± 0.056
7.031ValGly: 7.031 ± 0.086
1.591ValHis: 1.591 ± 0.037
4.235ValIle: 4.235 ± 0.07
1.492ValLys: 1.492 ± 0.04
9.427ValLeu: 9.427 ± 0.121
1.412ValMet: 1.412 ± 0.038
1.946ValAsn: 1.946 ± 0.046
4.725ValPro: 4.725 ± 0.071
2.211ValGln: 2.211 ± 0.048
5.542ValArg: 5.542 ± 0.071
5.545ValSer: 5.545 ± 0.071
6.154ValThr: 6.154 ± 0.108
9.168ValVal: 9.168 ± 0.12
1.194ValTrp: 1.194 ± 0.036
1.772ValTyr: 1.772 ± 0.043
0.0ValXaa: 0.0 ± 0.0
Trp
1.58TrpAla: 1.58 ± 0.038
0.089TrpCys: 0.089 ± 0.009
0.723TrpAsp: 0.723 ± 0.026
0.61TrpGlu: 0.61 ± 0.022
0.579TrpPhe: 0.579 ± 0.025
1.015TrpGly: 1.015 ± 0.035
0.327TrpHis: 0.327 ± 0.017
0.727TrpIle: 0.727 ± 0.026
0.306TrpLys: 0.306 ± 0.016
1.795TrpLeu: 1.795 ± 0.051
0.319TrpMet: 0.319 ± 0.016
0.485TrpAsn: 0.485 ± 0.022
0.717TrpPro: 0.717 ± 0.026
0.612TrpGln: 0.612 ± 0.024
1.148TrpArg: 1.148 ± 0.032
1.066TrpSer: 1.066 ± 0.029
0.909TrpThr: 0.909 ± 0.034
1.057TrpVal: 1.057 ± 0.03
0.361TrpTrp: 0.361 ± 0.019
0.308TrpTyr: 0.308 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.288TyrAla: 2.288 ± 0.045
0.136TyrCys: 0.136 ± 0.012
1.415TyrAsp: 1.415 ± 0.038
1.238TyrGlu: 1.238 ± 0.033
0.76TyrPhe: 0.76 ± 0.026
1.995TyrGly: 1.995 ± 0.041
0.334TyrHis: 0.334 ± 0.017
0.727TyrIle: 0.727 ± 0.022
0.355TyrLys: 0.355 ± 0.019
2.382TyrLeu: 2.382 ± 0.047
0.261TyrMet: 0.261 ± 0.015
0.52TyrAsn: 0.52 ± 0.022
1.077TyrPro: 1.077 ± 0.029
0.635TyrGln: 0.635 ± 0.027
1.668TyrArg: 1.668 ± 0.039
1.317TyrSer: 1.317 ± 0.04
1.363TyrThr: 1.363 ± 0.049
1.597TyrVal: 1.597 ± 0.046
0.355TyrTrp: 0.355 ± 0.019
0.491TyrTyr: 0.491 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3422 proteins (1170212 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski