Amino acid dipepetide frequency for Wenling crustacean virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.483AlaAla: 8.483 ± 2.328
1.018AlaCys: 1.018 ± 0.554
4.072AlaAsp: 4.072 ± 2.366
4.751AlaGlu: 4.751 ± 2.587
1.357AlaPhe: 1.357 ± 0.166
4.751AlaGly: 4.751 ± 0.295
2.036AlaHis: 2.036 ± 0.536
3.733AlaIle: 3.733 ± 0.314
3.393AlaLys: 3.393 ± 1.275
5.09AlaLeu: 5.09 ± 0.48
0.339AlaMet: 0.339 ± 0.224
1.697AlaAsn: 1.697 ± 0.795
4.411AlaPro: 4.411 ± 0.683
6.447AlaGln: 6.447 ± 0.499
4.751AlaArg: 4.751 ± 0.278
3.733AlaSer: 3.733 ± 1.405
4.751AlaThr: 4.751 ± 0.295
6.447AlaVal: 6.447 ± 0.073
1.697AlaTrp: 1.697 ± 0.795
1.697AlaTyr: 1.697 ± 0.351
0.0AlaXaa: 0.0 ± 0.0
Cys
0.679CysAla: 0.679 ± 0.37
0.339CysCys: 0.339 ± 0.185
1.697CysAsp: 1.697 ± 0.222
1.357CysGlu: 1.357 ± 0.739
0.339CysPhe: 0.339 ± 0.185
0.679CysGly: 0.679 ± 0.37
0.339CysHis: 0.339 ± 0.185
0.339CysIle: 0.339 ± 0.185
1.018CysLys: 1.018 ± 0.019
1.018CysLeu: 1.018 ± 0.019
0.0CysMet: 0.0 ± 0.0
1.357CysAsn: 1.357 ± 0.166
2.036CysPro: 2.036 ± 0.037
0.679CysGln: 0.679 ± 0.37
1.018CysArg: 1.018 ± 0.019
0.679CysSer: 0.679 ± 0.37
1.357CysThr: 1.357 ± 0.166
0.679CysVal: 0.679 ± 0.37
0.339CysTrp: 0.339 ± 0.185
0.339CysTyr: 0.339 ± 0.185
0.0CysXaa: 0.0 ± 0.0
Asp
3.054AspAla: 3.054 ± 0.629
1.357AspCys: 1.357 ± 0.166
3.733AspAsp: 3.733 ± 0.314
2.715AspGlu: 2.715 ± 0.813
4.072AspPhe: 4.072 ± 0.499
2.715AspGly: 2.715 ± 0.332
0.679AspHis: 0.679 ± 0.203
3.733AspIle: 3.733 ± 1.405
4.751AspLys: 4.751 ± 0.278
6.108AspLeu: 6.108 ± 0.461
1.018AspMet: 1.018 ± 0.554
3.054AspAsn: 3.054 ± 1.774
3.733AspPro: 3.733 ± 0.887
2.375AspGln: 2.375 ± 0.148
2.715AspArg: 2.715 ± 0.332
3.733AspSer: 3.733 ± 0.259
3.054AspThr: 3.054 ± 0.629
4.411AspVal: 4.411 ± 2.181
0.679AspTrp: 0.679 ± 0.203
2.715AspTyr: 2.715 ± 0.332
0.0AspXaa: 0.0 ± 0.0
Glu
3.733GluAla: 3.733 ± 0.314
0.0GluCys: 0.0 ± 0.0
3.054GluAsp: 3.054 ± 0.629
4.751GluGlu: 4.751 ± 1.441
0.679GluPhe: 0.679 ± 0.37
2.375GluGly: 2.375 ± 0.425
0.679GluHis: 0.679 ± 0.37
4.751GluIle: 4.751 ± 0.85
3.733GluLys: 3.733 ± 1.46
3.054GluLeu: 3.054 ± 1.663
2.375GluMet: 2.375 ± 0.425
3.733GluAsn: 3.733 ± 1.46
0.679GluPro: 0.679 ± 0.776
2.715GluGln: 2.715 ± 1.478
1.697GluArg: 1.697 ± 0.351
2.375GluSer: 2.375 ± 0.148
4.072GluThr: 4.072 ± 0.074
3.733GluVal: 3.733 ± 0.259
1.018GluTrp: 1.018 ± 0.019
4.751GluTyr: 4.751 ± 1.441
0.0GluXaa: 0.0 ± 0.0
Phe
3.393PheAla: 3.393 ± 0.444
1.018PheCys: 1.018 ± 0.554
4.751PheAsp: 4.751 ± 0.868
1.357PheGlu: 1.357 ± 0.98
2.715PhePhe: 2.715 ± 0.813
2.715PheGly: 2.715 ± 0.24
1.018PheHis: 1.018 ± 0.019
3.054PheIle: 3.054 ± 1.201
2.036PheLys: 2.036 ± 0.536
5.769PheLeu: 5.769 ± 0.277
1.018PheMet: 1.018 ± 0.019
2.375PheAsn: 2.375 ± 0.148
1.697PhePro: 1.697 ± 0.222
2.036PheGln: 2.036 ± 0.037
2.036PheArg: 2.036 ± 0.61
4.072PheSer: 4.072 ± 0.499
1.697PheThr: 1.697 ± 0.222
1.697PheVal: 1.697 ± 0.222
0.339PheTrp: 0.339 ± 0.185
1.018PheTyr: 1.018 ± 0.019
0.0PheXaa: 0.0 ± 0.0
Gly
3.393GlyAla: 3.393 ± 0.444
0.339GlyCys: 0.339 ± 0.388
4.751GlyAsp: 4.751 ± 0.295
3.054GlyGlu: 3.054 ± 0.629
2.715GlyPhe: 2.715 ± 0.905
2.375GlyGly: 2.375 ± 0.998
0.679GlyHis: 0.679 ± 0.37
5.429GlyIle: 5.429 ± 1.238
3.393GlyLys: 3.393 ± 0.129
3.393GlyLeu: 3.393 ± 0.702
1.018GlyMet: 1.018 ± 0.019
4.072GlyAsn: 4.072 ± 0.074
2.375GlyPro: 2.375 ± 1.571
1.357GlyGln: 1.357 ± 0.98
3.393GlyArg: 3.393 ± 0.129
3.733GlySer: 3.733 ± 0.832
5.09GlyThr: 5.09 ± 2.384
4.411GlyVal: 4.411 ± 1.829
0.339GlyTrp: 0.339 ± 0.388
1.697GlyTyr: 1.697 ± 0.222
0.0GlyXaa: 0.0 ± 0.0
His
1.018HisAla: 1.018 ± 0.591
0.0HisCys: 0.0 ± 0.0
0.339HisAsp: 0.339 ± 0.388
1.018HisGlu: 1.018 ± 0.591
0.679HisPhe: 0.679 ± 0.37
0.679HisGly: 0.679 ± 0.37
0.339HisHis: 0.339 ± 0.185
1.697HisIle: 1.697 ± 0.924
0.339HisLys: 0.339 ± 0.388
2.036HisLeu: 2.036 ± 1.109
0.679HisMet: 0.679 ± 0.203
0.339HisAsn: 0.339 ± 0.185
0.679HisPro: 0.679 ± 0.37
0.679HisGln: 0.679 ± 0.203
0.0HisArg: 0.0 ± 0.0
2.375HisSer: 2.375 ± 0.72
2.036HisThr: 2.036 ± 0.536
1.018HisVal: 1.018 ± 0.554
0.339HisTrp: 0.339 ± 0.185
0.679HisTyr: 0.679 ± 0.37
0.0HisXaa: 0.0 ± 0.0
Ile
5.429IleAla: 5.429 ± 0.092
1.697IleCys: 1.697 ± 0.351
6.447IleAsp: 6.447 ± 1.219
5.769IleGlu: 5.769 ± 0.85
2.375IlePhe: 2.375 ± 0.425
2.375IleGly: 2.375 ± 0.425
1.357IleHis: 1.357 ± 0.166
1.697IleIle: 1.697 ± 0.924
2.715IleLys: 2.715 ± 0.905
3.393IleLeu: 3.393 ± 0.702
2.036IleMet: 2.036 ± 0.536
3.733IleAsn: 3.733 ± 0.887
4.411IlePro: 4.411 ± 1.608
3.393IleGln: 3.393 ± 0.702
4.751IleArg: 4.751 ± 0.278
4.072IleSer: 4.072 ± 0.074
5.09IleThr: 5.09 ± 0.093
3.393IleVal: 3.393 ± 0.702
0.0IleTrp: 0.0 ± 0.0
2.036IleTyr: 2.036 ± 0.037
0.0IleXaa: 0.0 ± 0.0
Lys
3.393LysAla: 3.393 ± 0.702
0.679LysCys: 0.679 ± 0.37
3.054LysAsp: 3.054 ± 0.056
2.036LysGlu: 2.036 ± 1.109
2.375LysPhe: 2.375 ± 1.293
2.715LysGly: 2.715 ± 0.905
1.018LysHis: 1.018 ± 0.019
6.108LysIle: 6.108 ± 1.607
2.715LysLys: 2.715 ± 1.478
4.072LysLeu: 4.072 ± 0.647
1.018LysMet: 1.018 ± 0.554
2.375LysAsn: 2.375 ± 0.72
2.036LysPro: 2.036 ± 0.037
1.697LysGln: 1.697 ± 0.924
3.393LysArg: 3.393 ± 0.702
4.411LysSer: 4.411 ± 0.683
5.09LysThr: 5.09 ± 0.666
2.375LysVal: 2.375 ± 1.571
0.0LysTrp: 0.0 ± 0.0
2.036LysTyr: 2.036 ± 0.037
0.0LysXaa: 0.0 ± 0.0
Leu
7.465LeuAla: 7.465 ± 0.628
0.339LeuCys: 0.339 ± 0.185
2.715LeuAsp: 2.715 ± 1.386
5.09LeuGlu: 5.09 ± 1.053
1.697LeuPhe: 1.697 ± 0.222
5.769LeuGly: 5.769 ± 0.296
1.357LeuHis: 1.357 ± 0.739
5.769LeuIle: 5.769 ± 0.85
6.787LeuLys: 6.787 ± 0.258
7.126LeuLeu: 7.126 ± 1.589
1.357LeuMet: 1.357 ± 0.166
3.393LeuAsn: 3.393 ± 0.129
2.375LeuPro: 2.375 ± 0.72
3.733LeuGln: 3.733 ± 0.887
1.697LeuArg: 1.697 ± 0.222
4.411LeuSer: 4.411 ± 0.462
6.108LeuThr: 6.108 ± 0.461
6.787LeuVal: 6.787 ± 0.831
1.018LeuTrp: 1.018 ± 0.019
2.036LeuTyr: 2.036 ± 0.61
0.0LeuXaa: 0.0 ± 0.0
Met
1.697MetAla: 1.697 ± 0.351
1.018MetCys: 1.018 ± 0.019
0.679MetAsp: 0.679 ± 0.37
0.679MetGlu: 0.679 ± 0.37
0.679MetPhe: 0.679 ± 0.37
1.018MetGly: 1.018 ± 0.591
0.339MetHis: 0.339 ± 0.185
1.018MetIle: 1.018 ± 0.554
0.679MetLys: 0.679 ± 0.203
2.375MetLeu: 2.375 ± 0.148
0.339MetMet: 0.339 ± 0.388
1.697MetAsn: 1.697 ± 0.222
0.0MetPro: 0.0 ± 0.0
1.018MetGln: 1.018 ± 0.554
0.679MetArg: 0.679 ± 0.37
2.375MetSer: 2.375 ± 2.144
0.679MetThr: 0.679 ± 0.203
1.357MetVal: 1.357 ± 0.407
0.339MetTrp: 0.339 ± 0.185
1.018MetTyr: 1.018 ± 0.554
0.0MetXaa: 0.0 ± 0.0
Asn
2.715AsnAla: 2.715 ± 0.813
0.679AsnCys: 0.679 ± 0.37
3.054AsnAsp: 3.054 ± 0.056
0.339AsnGlu: 0.339 ± 0.185
4.411AsnPhe: 4.411 ± 0.683
3.393AsnGly: 3.393 ± 0.702
0.339AsnHis: 0.339 ± 0.185
3.393AsnIle: 3.393 ± 0.444
2.036AsnLys: 2.036 ± 1.109
4.411AsnLeu: 4.411 ± 1.608
0.679AsnMet: 0.679 ± 0.37
2.715AsnAsn: 2.715 ± 0.905
4.411AsnPro: 4.411 ± 0.111
3.054AsnGln: 3.054 ± 1.201
2.036AsnArg: 2.036 ± 1.109
2.715AsnSer: 2.715 ± 0.24
4.751AsnThr: 4.751 ± 0.85
2.715AsnVal: 2.715 ± 0.24
0.679AsnTrp: 0.679 ± 0.37
3.393AsnTyr: 3.393 ± 1.589
0.0AsnXaa: 0.0 ± 0.0
Pro
3.393ProAla: 3.393 ± 1.848
0.679ProCys: 0.679 ± 0.37
1.357ProAsp: 1.357 ± 0.407
3.054ProGlu: 3.054 ± 1.774
2.036ProPhe: 2.036 ± 1.183
3.393ProGly: 3.393 ± 0.129
0.339ProHis: 0.339 ± 0.185
4.411ProIle: 4.411 ± 0.462
2.036ProLys: 2.036 ± 1.109
2.715ProLeu: 2.715 ± 0.332
1.697ProMet: 1.697 ± 0.222
2.036ProAsn: 2.036 ± 0.037
2.036ProPro: 2.036 ± 0.61
2.715ProGln: 2.715 ± 0.24
1.697ProArg: 1.697 ± 0.924
3.393ProSer: 3.393 ± 0.444
4.751ProThr: 4.751 ± 1.423
4.411ProVal: 4.411 ± 1.035
0.339ProTrp: 0.339 ± 0.388
3.733ProTyr: 3.733 ± 1.405
0.0ProXaa: 0.0 ± 0.0
Gln
3.054GlnAla: 3.054 ± 0.629
1.018GlnCys: 1.018 ± 0.019
1.357GlnAsp: 1.357 ± 0.98
1.018GlnGlu: 1.018 ± 0.019
2.715GlnPhe: 2.715 ± 0.332
3.393GlnGly: 3.393 ± 0.702
1.697GlnHis: 1.697 ± 0.924
2.375GlnIle: 2.375 ± 0.72
2.375GlnLys: 2.375 ± 0.72
3.393GlnLeu: 3.393 ± 0.129
1.697GlnMet: 1.697 ± 0.222
2.715GlnAsn: 2.715 ± 0.813
3.393GlnPro: 3.393 ± 0.444
2.375GlnGln: 2.375 ± 0.425
3.393GlnArg: 3.393 ± 1.848
4.072GlnSer: 4.072 ± 1.071
3.733GlnThr: 3.733 ± 1.978
3.393GlnVal: 3.393 ± 0.702
0.0GlnTrp: 0.0 ± 0.0
2.375GlnTyr: 2.375 ± 0.425
0.0GlnXaa: 0.0 ± 0.0
Arg
3.054ArgAla: 3.054 ± 0.517
2.036ArgCys: 2.036 ± 0.037
2.715ArgAsp: 2.715 ± 0.332
2.375ArgGlu: 2.375 ± 0.148
2.375ArgPhe: 2.375 ± 0.425
2.715ArgGly: 2.715 ± 0.813
1.018ArgHis: 1.018 ± 0.591
3.393ArgIle: 3.393 ± 1.275
3.733ArgLys: 3.733 ± 0.887
2.036ArgLeu: 2.036 ± 0.037
0.0ArgMet: 0.0 ± 0.0
2.036ArgAsn: 2.036 ± 0.037
2.715ArgPro: 2.715 ± 0.24
4.072ArgGln: 4.072 ± 1.644
2.715ArgArg: 2.715 ± 0.24
1.357ArgSer: 1.357 ± 0.739
4.411ArgThr: 4.411 ± 1.035
3.393ArgVal: 3.393 ± 0.444
0.0ArgTrp: 0.0 ± 0.0
1.697ArgTyr: 1.697 ± 0.222
0.0ArgXaa: 0.0 ± 0.0
Ser
4.072SerAla: 4.072 ± 0.074
1.357SerCys: 1.357 ± 0.166
3.054SerAsp: 3.054 ± 0.056
2.715SerGlu: 2.715 ± 0.332
3.733SerPhe: 3.733 ± 1.405
4.411SerGly: 4.411 ± 0.462
1.018SerHis: 1.018 ± 0.019
3.733SerIle: 3.733 ± 0.832
3.054SerLys: 3.054 ± 0.629
8.144SerLeu: 8.144 ± 1.57
0.679SerMet: 0.679 ± 0.203
4.751SerAsn: 4.751 ± 0.278
3.393SerPro: 3.393 ± 0.444
4.411SerGln: 4.411 ± 1.035
2.036SerArg: 2.036 ± 0.037
3.393SerSer: 3.393 ± 2.162
5.769SerThr: 5.769 ± 1.442
3.393SerVal: 3.393 ± 0.444
0.339SerTrp: 0.339 ± 0.185
2.375SerTyr: 2.375 ± 0.425
0.0SerXaa: 0.0 ± 0.0
Thr
7.805ThrAla: 7.805 ± 0.333
1.018ThrCys: 1.018 ± 0.554
4.072ThrAsp: 4.072 ± 1.22
4.072ThrGlu: 4.072 ± 1.071
5.09ThrPhe: 5.09 ± 1.811
3.733ThrGly: 3.733 ± 1.405
1.357ThrHis: 1.357 ± 0.166
5.769ThrIle: 5.769 ± 0.85
3.054ThrLys: 3.054 ± 0.056
3.733ThrLeu: 3.733 ± 1.405
0.339ThrMet: 0.339 ± 0.185
5.09ThrAsn: 5.09 ± 1.239
3.393ThrPro: 3.393 ± 2.162
4.072ThrGln: 4.072 ± 0.074
3.393ThrArg: 3.393 ± 0.444
3.733ThrSer: 3.733 ± 1.978
6.108ThrThr: 6.108 ± 1.83
5.769ThrVal: 5.769 ± 1.442
0.339ThrTrp: 0.339 ± 0.185
2.715ThrTyr: 2.715 ± 0.905
0.0ThrXaa: 0.0 ± 0.0
Val
5.09ValAla: 5.09 ± 0.666
0.679ValCys: 0.679 ± 0.203
5.429ValAsp: 5.429 ± 0.665
3.733ValGlu: 3.733 ± 0.887
3.393ValPhe: 3.393 ± 0.444
4.751ValGly: 4.751 ± 0.85
0.679ValHis: 0.679 ± 0.37
3.393ValIle: 3.393 ± 0.129
2.036ValLys: 2.036 ± 0.037
4.072ValLeu: 4.072 ± 0.647
1.357ValMet: 1.357 ± 0.407
2.375ValAsn: 2.375 ± 0.148
4.751ValPro: 4.751 ± 0.278
1.357ValGln: 1.357 ± 0.166
3.733ValArg: 3.733 ± 0.832
8.823ValSer: 8.823 ± 2.07
3.054ValThr: 3.054 ± 1.201
4.411ValVal: 4.411 ± 1.608
1.357ValTrp: 1.357 ± 0.739
2.715ValTyr: 2.715 ± 0.905
0.0ValXaa: 0.0 ± 0.0
Trp
0.679TrpAla: 0.679 ± 0.37
0.339TrpCys: 0.339 ± 0.185
0.339TrpAsp: 0.339 ± 0.185
1.357TrpGlu: 1.357 ± 0.166
0.339TrpPhe: 0.339 ± 0.185
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.018TrpIle: 1.018 ± 0.554
0.679TrpLys: 0.679 ± 0.203
0.339TrpLeu: 0.339 ± 0.185
0.339TrpMet: 0.339 ± 0.315
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.679TrpArg: 0.679 ± 0.776
0.679TrpSer: 0.679 ± 0.203
0.339TrpThr: 0.339 ± 0.185
1.018TrpVal: 1.018 ± 0.019
0.0TrpTrp: 0.0 ± 0.0
1.357TrpTyr: 1.357 ± 0.166
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.054TyrAla: 3.054 ± 0.517
0.679TyrCys: 0.679 ± 0.37
3.733TyrAsp: 3.733 ± 0.832
2.715TyrGlu: 2.715 ± 0.905
2.036TyrPhe: 2.036 ± 0.61
3.054TyrGly: 3.054 ± 0.629
0.679TyrHis: 0.679 ± 0.203
1.357TyrIle: 1.357 ± 0.166
2.036TyrLys: 2.036 ± 0.037
4.751TyrLeu: 4.751 ± 0.295
1.357TyrMet: 1.357 ± 0.166
2.375TyrAsn: 2.375 ± 0.425
1.697TyrPro: 1.697 ± 0.924
1.357TyrGln: 1.357 ± 0.98
2.036TyrArg: 2.036 ± 0.61
1.697TyrSer: 1.697 ± 0.351
2.715TyrThr: 2.715 ± 0.905
2.375TyrVal: 2.375 ± 0.425
0.679TyrTrp: 0.679 ± 0.37
2.375TyrTyr: 2.375 ± 0.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2948 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski