Amino acid dipepetide frequency for Wenling tombus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.922AlaAla: 3.922 ± 2.444
0.784AlaCys: 0.784 ± 0.647
0.784AlaAsp: 0.784 ± 0.592
4.706AlaGlu: 4.706 ± 1.341
3.922AlaPhe: 3.922 ± 1.902
3.137AlaGly: 3.137 ± 1.366
2.353AlaHis: 2.353 ± 1.153
5.49AlaIle: 5.49 ± 0.821
4.706AlaLys: 4.706 ± 0.916
4.706AlaLeu: 4.706 ± 1.379
3.137AlaMet: 3.137 ± 1.299
2.353AlaAsn: 2.353 ± 0.648
3.922AlaPro: 3.922 ± 1.902
1.569AlaGln: 1.569 ± 0.848
3.137AlaArg: 3.137 ± 0.53
4.706AlaSer: 4.706 ± 1.86
3.137AlaThr: 3.137 ± 1.451
3.137AlaVal: 3.137 ± 1.593
3.137AlaTrp: 3.137 ± 1.697
3.922AlaTyr: 3.922 ± 2.163
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.784CysCys: 0.784 ± 0.592
0.0CysAsp: 0.0 ± 0.0
1.569CysGlu: 1.569 ± 1.294
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.784CysLys: 0.784 ± 0.833
2.353CysLeu: 2.353 ± 1.061
0.0CysMet: 0.0 ± 0.0
1.569CysAsn: 1.569 ± 0.848
1.569CysPro: 1.569 ± 0.65
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.784CysSer: 0.784 ± 0.647
0.784CysThr: 0.784 ± 0.833
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.784AspAla: 0.784 ± 0.647
0.0AspCys: 0.0 ± 0.0
3.137AspAsp: 3.137 ± 0.915
3.137AspGlu: 3.137 ± 0.915
1.569AspPhe: 1.569 ± 0.65
3.922AspGly: 3.922 ± 0.995
0.784AspHis: 0.784 ± 0.929
0.784AspIle: 0.784 ± 0.929
5.49AspLys: 5.49 ± 2.283
5.49AspLeu: 5.49 ± 1.451
0.784AspMet: 0.784 ± 0.647
0.784AspAsn: 0.784 ± 0.929
3.137AspPro: 3.137 ± 1.753
0.784AspGln: 0.784 ± 0.647
0.0AspArg: 0.0 ± 0.0
7.059AspSer: 7.059 ± 2.107
2.353AspThr: 2.353 ± 1.121
3.922AspVal: 3.922 ± 1.454
1.569AspTrp: 1.569 ± 0.848
0.784AspTyr: 0.784 ± 0.647
0.0AspXaa: 0.0 ± 0.0
Glu
3.922GluAla: 3.922 ± 1.757
1.569GluCys: 1.569 ± 0.791
2.353GluAsp: 2.353 ± 1.776
3.922GluGlu: 3.922 ± 2.786
0.784GluPhe: 0.784 ± 0.647
2.353GluGly: 2.353 ± 1.061
0.784GluHis: 0.784 ± 0.647
5.49GluIle: 5.49 ± 2.811
2.353GluLys: 2.353 ± 1.153
3.922GluLeu: 3.922 ± 1.962
0.784GluMet: 0.784 ± 0.498
0.784GluAsn: 0.784 ± 0.929
3.137GluPro: 3.137 ± 0.957
1.569GluGln: 1.569 ± 0.65
4.706GluArg: 4.706 ± 2.002
5.49GluSer: 5.49 ± 2.038
4.706GluThr: 4.706 ± 2.003
4.706GluVal: 4.706 ± 1.684
0.784GluTrp: 0.784 ± 0.929
3.137GluTyr: 3.137 ± 0.917
0.0GluXaa: 0.0 ± 0.0
Phe
1.569PheAla: 1.569 ± 1.294
0.784PheCys: 0.784 ± 0.647
4.706PheAsp: 4.706 ± 2.011
3.137PheGlu: 3.137 ± 1.366
1.569PhePhe: 1.569 ± 0.914
1.569PheGly: 1.569 ± 0.65
0.784PheHis: 0.784 ± 0.929
2.353PheIle: 2.353 ± 1.189
0.784PheLys: 0.784 ± 0.929
0.0PheLeu: 0.0 ± 0.0
0.784PheMet: 0.784 ± 0.567
1.569PheAsn: 1.569 ± 0.99
3.137PhePro: 3.137 ± 1.593
2.353PheGln: 2.353 ± 0.848
0.784PheArg: 0.784 ± 0.592
0.784PheSer: 0.784 ± 0.647
3.137PheThr: 3.137 ± 1.828
3.922PheVal: 3.922 ± 0.981
0.0PheTrp: 0.0 ± 0.0
0.784PheTyr: 0.784 ± 0.592
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
4.706GlyAsp: 4.706 ± 2.361
2.353GlyGlu: 2.353 ± 0.848
2.353GlyPhe: 2.353 ± 0.848
0.784GlyGly: 0.784 ± 0.833
1.569GlyHis: 1.569 ± 0.914
3.922GlyIle: 3.922 ± 2.332
1.569GlyLys: 1.569 ± 0.65
4.706GlyLeu: 4.706 ± 1.379
0.784GlyMet: 0.784 ± 0.833
2.353GlyAsn: 2.353 ± 0.7
2.353GlyPro: 2.353 ± 1.18
0.784GlyGln: 0.784 ± 0.647
11.765GlyArg: 11.765 ± 8.87
1.569GlySer: 1.569 ± 0.65
6.275GlyThr: 6.275 ± 2.192
4.706GlyVal: 4.706 ± 2.742
1.569GlyTrp: 1.569 ± 1.184
3.137GlyTyr: 3.137 ± 0.957
0.0GlyXaa: 0.0 ± 0.0
His
1.569HisAla: 1.569 ± 1.294
0.0HisCys: 0.0 ± 0.0
2.353HisAsp: 2.353 ± 1.295
1.569HisGlu: 1.569 ± 1.184
0.0HisPhe: 0.0 ± 0.0
0.784HisGly: 0.784 ± 0.647
1.569HisHis: 1.569 ± 0.848
2.353HisIle: 2.353 ± 0.7
0.0HisLys: 0.0 ± 0.0
2.353HisLeu: 2.353 ± 1.18
0.784HisMet: 0.784 ± 0.592
0.0HisAsn: 0.0 ± 0.0
2.353HisPro: 2.353 ± 1.295
0.784HisGln: 0.784 ± 0.647
1.569HisArg: 1.569 ± 0.99
1.569HisSer: 1.569 ± 0.848
3.137HisThr: 3.137 ± 0.915
1.569HisVal: 1.569 ± 0.791
1.569HisTrp: 1.569 ± 0.914
0.784HisTyr: 0.784 ± 0.647
0.0HisXaa: 0.0 ± 0.0
Ile
3.922IleAla: 3.922 ± 1.588
0.0IleCys: 0.0 ± 0.0
2.353IleAsp: 2.353 ± 1.94
4.706IleGlu: 4.706 ± 1.4
0.784IlePhe: 0.784 ± 0.647
3.137IleGly: 3.137 ± 1.344
2.353IleHis: 2.353 ± 1.18
1.569IleIle: 1.569 ± 0.65
4.706IleLys: 4.706 ± 1.4
5.49IleLeu: 5.49 ± 2.552
0.784IleMet: 0.784 ± 1.068
0.784IleAsn: 0.784 ± 0.592
4.706IlePro: 4.706 ± 2.003
3.137IleGln: 3.137 ± 1.753
2.353IleArg: 2.353 ± 1.645
3.137IleSer: 3.137 ± 0.981
5.49IleThr: 5.49 ± 1.141
3.137IleVal: 3.137 ± 0.53
0.0IleTrp: 0.0 ± 0.0
1.569IleTyr: 1.569 ± 0.791
0.0IleXaa: 0.0 ± 0.0
Lys
7.843LysAla: 7.843 ± 1.967
0.0LysCys: 0.0 ± 0.0
2.353LysAsp: 2.353 ± 0.7
2.353LysGlu: 2.353 ± 1.061
7.059LysPhe: 7.059 ± 2.311
3.922LysGly: 3.922 ± 0.737
2.353LysHis: 2.353 ± 0.648
2.353LysIle: 2.353 ± 0.7
2.353LysLys: 2.353 ± 1.061
3.922LysLeu: 3.922 ± 2.353
2.353LysMet: 2.353 ± 1.189
2.353LysAsn: 2.353 ± 1.061
3.922LysPro: 3.922 ± 1.449
3.137LysGln: 3.137 ± 2.587
3.922LysArg: 3.922 ± 2.378
1.569LysSer: 1.569 ± 0.99
0.784LysThr: 0.784 ± 0.592
4.706LysVal: 4.706 ± 1.377
0.784LysTrp: 0.784 ± 0.647
4.706LysTyr: 4.706 ± 1.949
0.0LysXaa: 0.0 ± 0.0
Leu
7.059LeuAla: 7.059 ± 2.315
0.0LeuCys: 0.0 ± 0.0
3.922LeuAsp: 3.922 ± 1.404
3.922LeuGlu: 3.922 ± 1.449
3.137LeuPhe: 3.137 ± 0.981
3.922LeuGly: 3.922 ± 1.319
0.784LeuHis: 0.784 ± 0.592
2.353LeuIle: 2.353 ± 0.648
9.412LeuLys: 9.412 ± 2.344
3.137LeuLeu: 3.137 ± 1.716
5.49LeuMet: 5.49 ± 2.384
3.137LeuAsn: 3.137 ± 1.593
6.275LeuPro: 6.275 ± 0.799
0.0LeuGln: 0.0 ± 0.0
5.49LeuArg: 5.49 ± 2.23
7.843LeuSer: 7.843 ± 3.275
3.137LeuThr: 3.137 ± 0.957
4.706LeuVal: 4.706 ± 1.228
0.784LeuTrp: 0.784 ± 0.647
4.706LeuTyr: 4.706 ± 1.641
0.0LeuXaa: 0.0 ± 0.0
Met
1.569MetAla: 1.569 ± 1.184
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.569MetGlu: 1.569 ± 0.914
1.569MetPhe: 1.569 ± 0.65
0.784MetGly: 0.784 ± 0.592
0.784MetHis: 0.784 ± 0.647
0.0MetIle: 0.0 ± 0.0
2.353MetLys: 2.353 ± 1.061
3.137MetLeu: 3.137 ± 1.716
0.784MetMet: 0.784 ± 0.833
0.784MetAsn: 0.784 ± 0.833
2.353MetPro: 2.353 ± 1.645
2.353MetGln: 2.353 ± 0.648
1.569MetArg: 1.569 ± 1.184
1.569MetSer: 1.569 ± 1.294
3.137MetThr: 3.137 ± 0.917
3.137MetVal: 3.137 ± 0.915
0.0MetTrp: 0.0 ± 0.0
3.137MetTyr: 3.137 ± 2.549
0.0MetXaa: 0.0 ± 0.0
Asn
2.353AsnAla: 2.353 ± 1.061
0.0AsnCys: 0.0 ± 0.0
0.784AsnAsp: 0.784 ± 0.592
1.569AsnGlu: 1.569 ± 0.65
0.0AsnPhe: 0.0 ± 0.0
3.137AsnGly: 3.137 ± 1.753
0.0AsnHis: 0.0 ± 0.0
2.353AsnIle: 2.353 ± 2.786
3.137AsnLys: 3.137 ± 0.981
5.49AsnLeu: 5.49 ± 1.141
0.0AsnMet: 0.0 ± 0.0
1.569AsnAsn: 1.569 ± 0.65
2.353AsnPro: 2.353 ± 2.498
1.569AsnGln: 1.569 ± 1.184
0.784AsnArg: 0.784 ± 0.929
3.137AsnSer: 3.137 ± 0.963
0.784AsnThr: 0.784 ± 0.647
2.353AsnVal: 2.353 ± 0.648
0.784AsnTrp: 0.784 ± 0.833
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.922ProAla: 3.922 ± 2.528
0.784ProCys: 0.784 ± 0.592
0.784ProAsp: 0.784 ± 0.929
5.49ProGlu: 5.49 ± 0.821
0.784ProPhe: 0.784 ± 0.592
7.059ProGly: 7.059 ± 3.351
0.0ProHis: 0.0 ± 0.0
3.137ProIle: 3.137 ± 1.344
2.353ProLys: 2.353 ± 0.848
2.353ProLeu: 2.353 ± 1.18
3.137ProMet: 3.137 ± 1.582
1.569ProAsn: 1.569 ± 0.791
6.275ProPro: 6.275 ± 1.623
6.275ProGln: 6.275 ± 1.922
4.706ProArg: 4.706 ± 2.006
4.706ProSer: 4.706 ± 1.357
4.706ProThr: 4.706 ± 1.341
5.49ProVal: 5.49 ± 1.695
1.569ProTrp: 1.569 ± 0.791
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.137GlnAla: 3.137 ± 1.344
0.0GlnCys: 0.0 ± 0.0
1.569GlnAsp: 1.569 ± 0.65
2.353GlnGlu: 2.353 ± 1.153
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.784GlnHis: 0.784 ± 0.647
1.569GlnIle: 1.569 ± 1.294
2.353GlnLys: 2.353 ± 1.153
6.275GlnLeu: 6.275 ± 2.479
0.0GlnMet: 0.0 ± 0.0
3.137GlnAsn: 3.137 ± 0.917
3.922GlnPro: 3.922 ± 4.164
2.353GlnGln: 2.353 ± 0.648
4.706GlnArg: 4.706 ± 1.379
3.137GlnSer: 3.137 ± 1.366
2.353GlnThr: 2.353 ± 0.7
3.137GlnVal: 3.137 ± 2.587
0.0GlnTrp: 0.0 ± 0.0
3.137GlnTyr: 3.137 ± 0.915
0.0GlnXaa: 0.0 ± 0.0
Arg
6.275ArgAla: 6.275 ± 3.3
0.784ArgCys: 0.784 ± 0.592
3.137ArgAsp: 3.137 ± 0.53
1.569ArgGlu: 1.569 ± 1.184
0.784ArgPhe: 0.784 ± 0.647
9.412ArgGly: 9.412 ± 8.16
0.0ArgHis: 0.0 ± 0.0
2.353ArgIle: 2.353 ± 1.061
1.569ArgLys: 1.569 ± 1.184
2.353ArgLeu: 2.353 ± 1.153
1.569ArgMet: 1.569 ± 0.848
0.784ArgAsn: 0.784 ± 0.647
2.353ArgPro: 2.353 ± 1.18
4.706ArgGln: 4.706 ± 1.296
4.706ArgArg: 4.706 ± 3.914
8.627ArgSer: 8.627 ± 6.258
2.353ArgThr: 2.353 ± 0.648
7.059ArgVal: 7.059 ± 1.434
1.569ArgTrp: 1.569 ± 0.65
2.353ArgTyr: 2.353 ± 1.121
0.0ArgXaa: 0.0 ± 0.0
Ser
7.843SerAla: 7.843 ± 3.611
1.569SerCys: 1.569 ± 1.294
2.353SerAsp: 2.353 ± 1.061
2.353SerGlu: 2.353 ± 0.848
3.137SerPhe: 3.137 ± 2.549
3.922SerGly: 3.922 ± 1.422
5.49SerHis: 5.49 ± 0.921
5.49SerIle: 5.49 ± 1.509
5.49SerLys: 5.49 ± 1.864
6.275SerLeu: 6.275 ± 4.189
2.353SerMet: 2.353 ± 0.7
2.353SerAsn: 2.353 ± 1.776
3.137SerPro: 3.137 ± 0.917
0.784SerGln: 0.784 ± 0.929
1.569SerArg: 1.569 ± 0.791
12.549SerSer: 12.549 ± 8.058
3.137SerThr: 3.137 ± 1.731
3.922SerVal: 3.922 ± 1.944
0.784SerTrp: 0.784 ± 0.929
1.569SerTyr: 1.569 ± 0.65
0.0SerXaa: 0.0 ± 0.0
Thr
3.922ThrAla: 3.922 ± 1.319
0.0ThrCys: 0.0 ± 0.0
1.569ThrAsp: 1.569 ± 0.848
2.353ThrGlu: 2.353 ± 1.061
3.137ThrPhe: 3.137 ± 1.845
4.706ThrGly: 4.706 ± 1.696
1.569ThrHis: 1.569 ± 1.184
3.922ThrIle: 3.922 ± 1.208
3.137ThrLys: 3.137 ± 1.591
7.843ThrLeu: 7.843 ± 1.837
3.137ThrMet: 3.137 ± 0.957
2.353ThrAsn: 2.353 ± 0.648
3.922ThrPro: 3.922 ± 1.208
2.353ThrGln: 2.353 ± 1.49
3.922ThrArg: 3.922 ± 1.449
3.137ThrSer: 3.137 ± 0.915
4.706ThrThr: 4.706 ± 3.483
1.569ThrVal: 1.569 ± 0.914
0.784ThrTrp: 0.784 ± 0.647
3.137ThrTyr: 3.137 ± 0.963
0.0ThrXaa: 0.0 ± 0.0
Val
5.49ValAla: 5.49 ± 1.506
2.353ValCys: 2.353 ± 0.648
4.706ValAsp: 4.706 ± 2.123
6.275ValGlu: 6.275 ± 3.643
2.353ValPhe: 2.353 ± 0.848
1.569ValGly: 1.569 ± 0.791
0.784ValHis: 0.784 ± 0.592
5.49ValIle: 5.49 ± 1.695
5.49ValLys: 5.49 ± 1.551
4.706ValLeu: 4.706 ± 1.23
0.0ValMet: 0.0 ± 0.0
0.784ValAsn: 0.784 ± 0.647
3.137ValPro: 3.137 ± 1.366
5.49ValGln: 5.49 ± 1.021
4.706ValArg: 4.706 ± 0.916
3.137ValSer: 3.137 ± 1.845
3.922ValThr: 3.922 ± 1.928
6.275ValVal: 6.275 ± 2.101
1.569ValTrp: 1.569 ± 1.161
3.137ValTyr: 3.137 ± 0.963
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.569TrpAsp: 1.569 ± 0.848
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.569TrpGly: 1.569 ± 1.666
1.569TrpHis: 1.569 ± 0.65
2.353TrpIle: 2.353 ± 0.7
3.137TrpLys: 3.137 ± 1.511
0.784TrpLeu: 0.784 ± 0.833
1.569TrpMet: 1.569 ± 0.914
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.569TrpGln: 1.569 ± 0.848
0.0TrpArg: 0.0 ± 0.0
0.784TrpSer: 0.784 ± 0.647
0.0TrpThr: 0.0 ± 0.0
2.353TrpVal: 2.353 ± 1.189
0.0TrpTrp: 0.0 ± 0.0
0.784TrpTyr: 0.784 ± 0.592
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.569TyrAla: 1.569 ± 0.848
0.784TyrCys: 0.784 ± 0.929
3.137TyrAsp: 3.137 ± 1.299
2.353TyrGlu: 2.353 ± 1.18
1.569TyrPhe: 1.569 ± 0.848
1.569TyrGly: 1.569 ± 0.848
2.353TyrHis: 2.353 ± 0.648
1.569TyrIle: 1.569 ± 1.184
1.569TyrLys: 1.569 ± 0.914
3.922TyrLeu: 3.922 ± 1.757
1.569TyrMet: 1.569 ± 0.65
3.137TyrAsn: 3.137 ± 0.963
3.137TyrPro: 3.137 ± 2.322
2.353TyrGln: 2.353 ± 1.153
3.922TyrArg: 3.922 ± 1.422
0.784TyrSer: 0.784 ± 0.592
3.137TyrThr: 3.137 ± 0.53
1.569TyrVal: 1.569 ± 0.914
0.784TyrTrp: 0.784 ± 0.592
1.569TyrTyr: 1.569 ± 0.848
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1276 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski