Human PoSCV5-like circular virus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; unclassified Circoviridae

Average proteome isoelectric point is 7.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2D0WHQ3|A0A2D0WHQ3_9CIRC Cap protein OS=Human PoSCV5-like circular virus OX=1965018 PE=4 SV=1
MM1 pKa = 7.63LSHH4 pKa = 7.08SSCKK8 pKa = 10.22LLNAKK13 pKa = 10.05RR14 pKa = 11.84FLLTYY19 pKa = 10.35NDD21 pKa = 3.46VXGKK25 pKa = 10.14IPSALDD31 pKa = 3.56LSEE34 pKa = 5.0HH35 pKa = 6.96LINLTSEE42 pKa = 3.63KK43 pKa = 9.96MEE45 pKa = 3.73FVVVSEE51 pKa = 4.38EE52 pKa = 4.14TAPTTGMIHH61 pKa = 5.05YY62 pKa = 8.3HH63 pKa = 6.2ALVILKK69 pKa = 10.46DD70 pKa = 3.53NLYY73 pKa = 10.69SRR75 pKa = 11.84KK76 pKa = 9.53LDD78 pKa = 3.52YY79 pKa = 10.78FDD81 pKa = 5.38YY82 pKa = 11.5LMIHH86 pKa = 6.61PNIEE90 pKa = 3.98AVRR93 pKa = 11.84GNAQKK98 pKa = 10.68AYY100 pKa = 9.98EE101 pKa = 3.97YY102 pKa = 10.59VIKK105 pKa = 10.46DD106 pKa = 3.3GKK108 pKa = 9.93YY109 pKa = 7.86WQTDD113 pKa = 3.32LNYY116 pKa = 10.39FKK118 pKa = 11.3VDD120 pKa = 3.16GGKK123 pKa = 10.36KK124 pKa = 8.8NNEE127 pKa = 3.23RR128 pKa = 11.84RR129 pKa = 11.84EE130 pKa = 4.07RR131 pKa = 11.84NKK133 pKa = 10.94LLMNGDD139 pKa = 3.05IFEE142 pKa = 4.67EE143 pKa = 4.56YY144 pKa = 10.22EE145 pKa = 4.14KK146 pKa = 11.59GNIGPIDD153 pKa = 5.08LIRR156 pKa = 11.84AAKK159 pKa = 9.44IRR161 pKa = 11.84AIKK164 pKa = 9.01VQYY167 pKa = 9.02NNNMTKK173 pKa = 9.26RR174 pKa = 11.84TPPLIMWFYY183 pKa = 11.24GNTGSGKK190 pKa = 6.62TRR192 pKa = 11.84KK193 pKa = 9.4AVEE196 pKa = 3.51IAEE199 pKa = 4.13EE200 pKa = 4.0LKK202 pKa = 11.0ARR204 pKa = 11.84IWISNDD210 pKa = 2.56NLKK213 pKa = 10.3WFDD216 pKa = 4.03GYY218 pKa = 10.87CGQEE222 pKa = 3.75VAVFDD227 pKa = 4.51DD228 pKa = 4.06LRR230 pKa = 11.84RR231 pKa = 11.84DD232 pKa = 3.86ILPTWAFLLRR242 pKa = 11.84LLDD245 pKa = 4.4RR246 pKa = 11.84YY247 pKa = 10.06PLIVQIKK254 pKa = 8.35GGFVKK259 pKa = 10.21WEE261 pKa = 3.87PKK263 pKa = 10.09IIIITCPVPPEE274 pKa = 4.33EE275 pKa = 4.74CFKK278 pKa = 10.48WYY280 pKa = 10.59NKK282 pKa = 9.82QGEE285 pKa = 4.28EE286 pKa = 4.08QQWDD290 pKa = 3.59RR291 pKa = 11.84QEE293 pKa = 3.9QLNRR297 pKa = 11.84RR298 pKa = 11.84LTWEE302 pKa = 4.12EE303 pKa = 3.88KK304 pKa = 8.11EE305 pKa = 4.08QVYY308 pKa = 9.0EE309 pKa = 4.45FPLSLGDD316 pKa = 3.84GEE318 pKa = 4.82EE319 pKa = 4.16MEE321 pKa = 4.64LTIEE325 pKa = 3.9NWKK328 pKa = 8.49TKK330 pKa = 10.16QADD333 pKa = 3.65DD334 pKa = 3.57NN335 pKa = 4.31

Molecular weight: 39.26 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2D0WHQ3|A0A2D0WHQ3_9CIRC Cap protein OS=Human PoSCV5-like circular virus OX=1965018 PE=4 SV=1
MM1 pKa = 7.72AKK3 pKa = 9.97RR4 pKa = 11.84YY5 pKa = 9.36ASRR8 pKa = 11.84KK9 pKa = 7.79RR10 pKa = 11.84VYY12 pKa = 9.64RR13 pKa = 11.84RR14 pKa = 11.84KK15 pKa = 9.77ARR17 pKa = 11.84KK18 pKa = 7.99PIKK21 pKa = 9.65RR22 pKa = 11.84FRR24 pKa = 11.84RR25 pKa = 11.84YY26 pKa = 8.73RR27 pKa = 11.84AKK29 pKa = 10.62ARR31 pKa = 11.84STAKK35 pKa = 10.11RR36 pKa = 11.84YY37 pKa = 9.18FRR39 pKa = 11.84LKK41 pKa = 9.99RR42 pKa = 11.84AARR45 pKa = 11.84NYY47 pKa = 10.86SKK49 pKa = 10.84VKK51 pKa = 9.83KK52 pKa = 9.68IRR54 pKa = 11.84RR55 pKa = 11.84AKK57 pKa = 9.77RR58 pKa = 11.84QYY60 pKa = 9.43KK61 pKa = 8.42TISGKK66 pKa = 8.26GVKK69 pKa = 9.78NKK71 pKa = 10.11LSKK74 pKa = 10.87LSISEE79 pKa = 4.8FIQLPYY85 pKa = 10.56YY86 pKa = 10.6DD87 pKa = 5.67LIRR90 pKa = 11.84LASMVCTRR98 pKa = 11.84HH99 pKa = 6.22SPTGYY104 pKa = 9.68PLTEE108 pKa = 3.69QAMQSFANLYY118 pKa = 9.91SEE120 pKa = 4.3QYY122 pKa = 10.16LYY124 pKa = 11.34KK125 pKa = 10.61LGAILPEE132 pKa = 3.96KK133 pKa = 10.62LFVNSNPFIIGADD146 pKa = 3.31RR147 pKa = 11.84SFTPYY152 pKa = 10.9LFGFNPILTPVTCGQKK168 pKa = 8.28MQIYY172 pKa = 9.9ASLYY176 pKa = 10.19SKK178 pKa = 10.47FKK180 pKa = 9.54YY181 pKa = 10.48VGVKK185 pKa = 9.95VSWHH189 pKa = 5.24PRR191 pKa = 11.84NRR193 pKa = 11.84AVSSYY198 pKa = 10.55LPSEE202 pKa = 4.44FKK204 pKa = 10.87VKK206 pKa = 10.56YY207 pKa = 10.37DD208 pKa = 3.59SDD210 pKa = 4.35VLSMAALTPNPAEE223 pKa = 4.86DD224 pKa = 4.32GVPSTIAQGNAMFTPKK240 pKa = 10.4DD241 pKa = 3.53RR242 pKa = 11.84LNQTIEE248 pKa = 4.04MTRR251 pKa = 11.84SEE253 pKa = 4.59ANVSGNYY260 pKa = 9.25YY261 pKa = 7.49MHH263 pKa = 7.08VYY265 pKa = 10.16FGKK268 pKa = 10.38QIEE271 pKa = 4.52SSEE274 pKa = 4.26TWDD277 pKa = 3.32LPYY280 pKa = 10.8YY281 pKa = 10.33RR282 pKa = 11.84WRR284 pKa = 11.84QMSGGQKK291 pKa = 9.72EE292 pKa = 4.81LSLQHH297 pKa = 6.37EE298 pKa = 4.59KK299 pKa = 10.9AKK301 pKa = 10.74HH302 pKa = 4.8NNKK305 pKa = 9.38GRR307 pKa = 11.84VKK309 pKa = 10.83ASLFYY314 pKa = 10.53DD315 pKa = 3.43IQTLLPCIEE324 pKa = 4.53TNSKK328 pKa = 8.82LHH330 pKa = 6.11KK331 pKa = 10.18VYY333 pKa = 11.13DD334 pKa = 3.55MSKK337 pKa = 8.64PFSFFVRR344 pKa = 11.84PMVVDD349 pKa = 3.81SSTVKK354 pKa = 10.43EE355 pKa = 4.13PNEE358 pKa = 3.91RR359 pKa = 11.84GAEE362 pKa = 4.14NIDD365 pKa = 4.27TIDD368 pKa = 4.16CNCQHH373 pKa = 6.79EE374 pKa = 4.87SLTKK378 pKa = 9.66GLKK381 pKa = 9.22HH382 pKa = 6.22LGYY385 pKa = 10.47RR386 pKa = 11.84SFDD389 pKa = 3.43HH390 pKa = 7.04ALVPSTIEE398 pKa = 3.75IPQDD402 pKa = 3.45NQEE405 pKa = 4.72LSDD408 pKa = 3.64LTQDD412 pKa = 2.56RR413 pKa = 11.84WYY415 pKa = 11.27YY416 pKa = 11.28NSDD419 pKa = 3.2DD420 pKa = 5.15DD421 pKa = 5.56NFFNPTLFWYY431 pKa = 10.55CFTTSDD437 pKa = 3.76NPVDD441 pKa = 3.69ASYY444 pKa = 11.05KK445 pKa = 9.78SHH447 pKa = 7.0SPYY450 pKa = 10.08QALASSFNNAQVPAGAPNGNARR472 pKa = 11.84YY473 pKa = 8.93EE474 pKa = 4.17LSSHH478 pKa = 6.81FGTYY482 pKa = 10.15NDD484 pKa = 4.51ALNQYY489 pKa = 10.36GYY491 pKa = 11.18FDD493 pKa = 3.34VTFYY497 pKa = 10.81TKK499 pKa = 9.92WKK501 pKa = 9.94GEE503 pKa = 3.91RR504 pKa = 11.84PLVSKK509 pKa = 10.74SSYY512 pKa = 9.05TGIVPSEE519 pKa = 4.11TGVTGLSTIISNN531 pKa = 4.03

Molecular weight: 61.01 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

866

335

531

433.0

50.14

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.774 ± 0.611

1.155 ± 0.024

4.965 ± 0.615

6.005 ± 1.806

4.388 ± 0.493

5.196 ± 0.291

1.848 ± 0.217

5.543 ± 1.175

8.199 ± 0.28

8.199 ± 1.011

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.194 ± 0.119

6.005 ± 0.344

4.85 ± 0.593

3.811 ± 0.14

6.005 ± 0.386

7.39 ± 2.513

5.312 ± 0.511

5.081 ± 0.186

1.848 ± 0.696

6.12 ± 0.823
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski