Amino acid dipepetide frequency for Guangdong red-banded snake torovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.488AlaAla: 3.488 ± 0.939
2.154AlaCys: 2.154 ± 0.652
1.949AlaAsp: 1.949 ± 0.486
1.641AlaGlu: 1.641 ± 0.622
2.359AlaPhe: 2.359 ± 0.333
2.154AlaGly: 2.154 ± 0.454
1.641AlaHis: 1.641 ± 0.616
4.308AlaIle: 4.308 ± 0.853
3.693AlaLys: 3.693 ± 0.185
5.129AlaLeu: 5.129 ± 0.883
0.513AlaMet: 0.513 ± 0.377
3.488AlaAsn: 3.488 ± 0.839
1.949AlaPro: 1.949 ± 0.582
1.949AlaGln: 1.949 ± 0.836
2.257AlaArg: 2.257 ± 0.712
3.693AlaSer: 3.693 ± 0.551
5.129AlaThr: 5.129 ± 0.991
4.103AlaVal: 4.103 ± 0.679
0.308AlaTrp: 0.308 ± 0.154
2.77AlaTyr: 2.77 ± 0.556
0.0AlaXaa: 0.0 ± 0.0
Cys
1.641CysAla: 1.641 ± 0.511
1.026CysCys: 1.026 ± 0.666
1.436CysAsp: 1.436 ± 0.293
1.333CysGlu: 1.333 ± 0.499
1.333CysPhe: 1.333 ± 0.518
1.539CysGly: 1.539 ± 0.23
0.718CysHis: 0.718 ± 0.341
2.154CysIle: 2.154 ± 0.26
1.231CysLys: 1.231 ± 0.293
2.257CysLeu: 2.257 ± 0.547
0.308CysMet: 0.308 ± 0.212
2.462CysAsn: 2.462 ± 0.585
1.128CysPro: 1.128 ± 0.856
1.641CysGln: 1.641 ± 0.652
0.923CysArg: 0.923 ± 0.296
1.744CysSer: 1.744 ± 0.698
1.744CysThr: 1.744 ± 0.665
1.641CysVal: 1.641 ± 0.648
0.103CysTrp: 0.103 ± 0.051
2.257CysTyr: 2.257 ± 0.541
0.0CysXaa: 0.0 ± 0.0
Asp
2.667AspAla: 2.667 ± 0.974
1.539AspCys: 1.539 ± 0.576
1.846AspAsp: 1.846 ± 0.749
2.462AspGlu: 2.462 ± 1.006
3.59AspPhe: 3.59 ± 0.623
2.154AspGly: 2.154 ± 0.686
0.821AspHis: 0.821 ± 0.269
3.488AspIle: 3.488 ± 0.516
3.077AspLys: 3.077 ± 0.6
4.308AspLeu: 4.308 ± 0.778
0.718AspMet: 0.718 ± 0.221
2.872AspAsn: 2.872 ± 0.584
2.359AspPro: 2.359 ± 0.708
3.077AspGln: 3.077 ± 0.57
1.333AspArg: 1.333 ± 0.267
4.0AspSer: 4.0 ± 0.607
3.488AspThr: 3.488 ± 0.969
2.667AspVal: 2.667 ± 0.307
0.718AspTrp: 0.718 ± 0.549
3.385AspTyr: 3.385 ± 0.598
0.0AspXaa: 0.0 ± 0.0
Glu
2.77GluAla: 2.77 ± 1.387
1.436GluCys: 1.436 ± 0.443
2.975GluAsp: 2.975 ± 1.146
3.282GluGlu: 3.282 ± 1.644
3.693GluPhe: 3.693 ± 0.763
1.949GluGly: 1.949 ± 0.485
1.846GluHis: 1.846 ± 0.717
2.154GluIle: 2.154 ± 0.525
2.462GluLys: 2.462 ± 0.624
3.488GluLeu: 3.488 ± 0.763
0.615GluMet: 0.615 ± 0.292
1.128GluAsn: 1.128 ± 0.18
1.128GluPro: 1.128 ± 0.401
1.641GluGln: 1.641 ± 0.411
1.333GluArg: 1.333 ± 0.486
3.795GluSer: 3.795 ± 0.94
3.59GluThr: 3.59 ± 0.786
3.282GluVal: 3.282 ± 1.156
0.513GluTrp: 0.513 ± 0.257
2.051GluTyr: 2.051 ± 0.85
0.0GluXaa: 0.0 ± 0.0
Phe
2.872PheAla: 2.872 ± 0.507
1.539PheCys: 1.539 ± 0.307
1.949PheAsp: 1.949 ± 0.423
2.154PheGlu: 2.154 ± 0.4
2.667PhePhe: 2.667 ± 0.599
3.18PheGly: 3.18 ± 0.592
1.436PheHis: 1.436 ± 0.548
3.59PheIle: 3.59 ± 1.065
2.564PheLys: 2.564 ± 0.467
4.821PheLeu: 4.821 ± 0.957
0.308PheMet: 0.308 ± 0.341
3.693PheAsn: 3.693 ± 0.481
1.949PhePro: 1.949 ± 0.398
2.051PheGln: 2.051 ± 0.566
1.641PheArg: 1.641 ± 0.413
4.308PheSer: 4.308 ± 0.341
4.616PheThr: 4.616 ± 1.229
4.206PheVal: 4.206 ± 1.156
0.308PheTrp: 0.308 ± 0.341
3.282PheTyr: 3.282 ± 1.012
0.0PheXaa: 0.0 ± 0.0
Gly
1.744GlyAla: 1.744 ± 0.435
1.436GlyCys: 1.436 ± 0.306
2.564GlyAsp: 2.564 ± 0.705
2.462GlyGlu: 2.462 ± 0.706
1.949GlyPhe: 1.949 ± 0.264
2.77GlyGly: 2.77 ± 0.568
1.026GlyHis: 1.026 ± 0.514
4.206GlyIle: 4.206 ± 0.641
2.462GlyLys: 2.462 ± 0.363
3.59GlyLeu: 3.59 ± 0.519
0.718GlyMet: 0.718 ± 0.669
1.846GlyAsn: 1.846 ± 0.502
2.359GlyPro: 2.359 ± 0.498
2.051GlyGln: 2.051 ± 0.532
2.051GlyArg: 2.051 ± 0.503
4.513GlySer: 4.513 ± 0.866
2.872GlyThr: 2.872 ± 0.504
2.77GlyVal: 2.77 ± 0.769
0.103GlyTrp: 0.103 ± 0.198
2.359GlyTyr: 2.359 ± 0.707
0.0GlyXaa: 0.0 ± 0.0
His
1.333HisAla: 1.333 ± 0.668
1.026HisCys: 1.026 ± 0.316
1.026HisAsp: 1.026 ± 0.338
0.41HisGlu: 0.41 ± 0.206
1.949HisPhe: 1.949 ± 0.574
1.026HisGly: 1.026 ± 0.338
1.333HisHis: 1.333 ± 0.472
1.231HisIle: 1.231 ± 0.617
1.539HisLys: 1.539 ± 0.362
3.59HisLeu: 3.59 ± 0.541
0.205HisMet: 0.205 ± 0.103
1.846HisAsn: 1.846 ± 0.571
1.436HisPro: 1.436 ± 0.416
2.257HisGln: 2.257 ± 0.913
1.333HisArg: 1.333 ± 0.486
2.359HisSer: 2.359 ± 0.716
1.846HisThr: 1.846 ± 0.244
1.744HisVal: 1.744 ± 0.259
0.41HisTrp: 0.41 ± 0.206
0.923HisTyr: 0.923 ± 0.122
0.0HisXaa: 0.0 ± 0.0
Ile
2.872IleAla: 2.872 ± 0.597
1.231IleCys: 1.231 ± 0.617
3.795IleAsp: 3.795 ± 0.223
2.872IleGlu: 2.872 ± 0.742
3.59IlePhe: 3.59 ± 1.246
2.359IleGly: 2.359 ± 0.99
2.667IleHis: 2.667 ± 0.529
4.103IleIle: 4.103 ± 0.648
4.821IleLys: 4.821 ± 1.238
5.334IleLeu: 5.334 ± 0.778
0.821IleMet: 0.821 ± 0.319
3.59IleAsn: 3.59 ± 1.033
4.0IlePro: 4.0 ± 0.628
3.488IleGln: 3.488 ± 0.928
2.872IleArg: 2.872 ± 1.075
6.257IleSer: 6.257 ± 0.977
4.513IleThr: 4.513 ± 0.997
3.488IleVal: 3.488 ± 0.562
0.513IleTrp: 0.513 ± 0.157
3.077IleTyr: 3.077 ± 1.061
0.0IleXaa: 0.0 ± 0.0
Lys
3.18LysAla: 3.18 ± 0.99
1.641LysCys: 1.641 ± 0.32
2.462LysAsp: 2.462 ± 0.373
3.693LysGlu: 3.693 ± 1.23
3.488LysPhe: 3.488 ± 0.921
2.257LysGly: 2.257 ± 0.448
1.949LysHis: 1.949 ± 0.64
4.616LysIle: 4.616 ± 0.446
3.077LysLys: 3.077 ± 0.682
4.616LysLeu: 4.616 ± 0.452
0.513LysMet: 0.513 ± 0.639
3.385LysAsn: 3.385 ± 0.368
3.693LysPro: 3.693 ± 0.535
2.462LysGln: 2.462 ± 0.444
2.462LysArg: 2.462 ± 0.718
4.616LysSer: 4.616 ± 1.47
3.385LysThr: 3.385 ± 0.929
4.308LysVal: 4.308 ± 0.853
0.41LysTrp: 0.41 ± 0.251
2.872LysTyr: 2.872 ± 0.95
0.0LysXaa: 0.0 ± 0.0
Leu
6.975LeuAla: 6.975 ± 0.699
2.359LeuCys: 2.359 ± 0.732
5.539LeuAsp: 5.539 ± 1.06
3.693LeuGlu: 3.693 ± 1.183
4.821LeuPhe: 4.821 ± 0.863
3.282LeuGly: 3.282 ± 0.43
2.872LeuHis: 2.872 ± 0.993
4.616LeuIle: 4.616 ± 0.878
4.206LeuLys: 4.206 ± 0.972
7.385LeuLeu: 7.385 ± 0.62
0.923LeuMet: 0.923 ± 0.331
4.411LeuAsn: 4.411 ± 1.315
5.949LeuPro: 5.949 ± 0.42
5.026LeuGln: 5.026 ± 1.148
4.308LeuArg: 4.308 ± 0.936
6.77LeuSer: 6.77 ± 1.45
4.718LeuThr: 4.718 ± 0.771
4.103LeuVal: 4.103 ± 1.393
0.513LeuTrp: 0.513 ± 0.157
4.206LeuTyr: 4.206 ± 0.806
0.0LeuXaa: 0.0 ± 0.0
Met
0.718MetAla: 0.718 ± 0.526
0.308MetCys: 0.308 ± 0.146
0.923MetAsp: 0.923 ± 0.462
0.41MetGlu: 0.41 ± 0.265
0.41MetPhe: 0.41 ± 0.265
0.103MetGly: 0.103 ± 0.051
0.103MetHis: 0.103 ± 0.051
0.308MetIle: 0.308 ± 0.212
0.615MetLys: 0.615 ± 0.207
1.641MetLeu: 1.641 ± 1.398
0.103MetMet: 0.103 ± 0.051
0.821MetAsn: 0.821 ± 0.269
0.821MetPro: 0.821 ± 0.293
0.41MetGln: 0.41 ± 0.265
0.513MetArg: 0.513 ± 0.257
0.718MetSer: 0.718 ± 0.306
1.026MetThr: 1.026 ± 0.145
0.821MetVal: 0.821 ± 0.263
0.0MetTrp: 0.0 ± 0.0
0.821MetTyr: 0.821 ± 0.969
0.0MetXaa: 0.0 ± 0.0
Asn
3.488AsnAla: 3.488 ± 1.041
1.026AsnCys: 1.026 ± 0.807
2.564AsnAsp: 2.564 ± 0.4
2.462AsnGlu: 2.462 ± 0.615
4.103AsnPhe: 4.103 ± 0.718
2.872AsnGly: 2.872 ± 0.556
1.436AsnHis: 1.436 ± 0.254
4.718AsnIle: 4.718 ± 0.527
4.411AsnLys: 4.411 ± 0.401
3.795AsnLeu: 3.795 ± 1.272
0.513AsnMet: 0.513 ± 0.467
4.513AsnAsn: 4.513 ± 0.532
2.975AsnPro: 2.975 ± 0.635
2.462AsnGln: 2.462 ± 1.379
1.846AsnArg: 1.846 ± 0.35
4.308AsnSer: 4.308 ± 0.655
4.616AsnThr: 4.616 ± 1.137
3.693AsnVal: 3.693 ± 0.623
0.308AsnTrp: 0.308 ± 0.402
2.462AsnTyr: 2.462 ± 0.908
0.0AsnXaa: 0.0 ± 0.0
Pro
1.846ProAla: 1.846 ± 0.615
0.821ProCys: 0.821 ± 0.333
1.949ProAsp: 1.949 ± 0.583
3.077ProGlu: 3.077 ± 0.796
2.359ProPhe: 2.359 ± 0.609
1.846ProGly: 1.846 ± 0.602
0.923ProHis: 0.923 ± 0.591
3.077ProIle: 3.077 ± 1.598
3.488ProLys: 3.488 ± 1.448
4.411ProLeu: 4.411 ± 1.039
0.41ProMet: 0.41 ± 0.143
1.333ProAsn: 1.333 ± 0.358
2.872ProPro: 2.872 ± 0.372
2.359ProGln: 2.359 ± 0.541
1.436ProArg: 1.436 ± 0.743
6.154ProSer: 6.154 ± 1.188
3.385ProThr: 3.385 ± 1.503
4.718ProVal: 4.718 ± 0.732
0.513ProTrp: 0.513 ± 0.157
1.846ProTyr: 1.846 ± 0.478
0.0ProXaa: 0.0 ± 0.0
Gln
3.488GlnAla: 3.488 ± 0.775
1.333GlnCys: 1.333 ± 0.267
1.949GlnAsp: 1.949 ± 0.763
2.359GlnGlu: 2.359 ± 0.465
1.949GlnPhe: 1.949 ± 0.796
2.564GlnGly: 2.564 ± 0.399
1.231GlnHis: 1.231 ± 0.37
3.077GlnIle: 3.077 ± 1.298
1.846GlnLys: 1.846 ± 0.499
4.103GlnLeu: 4.103 ± 0.633
0.923GlnMet: 0.923 ± 0.277
2.564GlnAsn: 2.564 ± 1.354
2.667GlnPro: 2.667 ± 1.851
2.359GlnGln: 2.359 ± 0.957
1.539GlnArg: 1.539 ± 0.641
3.488GlnSer: 3.488 ± 0.759
2.872GlnThr: 2.872 ± 0.62
4.206GlnVal: 4.206 ± 0.869
0.103GlnTrp: 0.103 ± 0.051
2.975GlnTyr: 2.975 ± 0.902
0.0GlnXaa: 0.0 ± 0.0
Arg
2.154ArgAla: 2.154 ± 0.824
1.333ArgCys: 1.333 ± 0.267
1.846ArgAsp: 1.846 ± 0.615
1.128ArgGlu: 1.128 ± 0.565
2.462ArgPhe: 2.462 ± 0.442
1.436ArgGly: 1.436 ± 0.509
1.333ArgHis: 1.333 ± 0.353
2.564ArgIle: 2.564 ± 0.643
2.257ArgLys: 2.257 ± 0.511
3.385ArgLeu: 3.385 ± 0.393
0.41ArgMet: 0.41 ± 0.15
1.436ArgAsn: 1.436 ± 0.584
1.641ArgPro: 1.641 ± 0.341
2.564ArgGln: 2.564 ± 0.643
1.641ArgArg: 1.641 ± 1.34
1.846ArgSer: 1.846 ± 0.964
2.564ArgThr: 2.564 ± 0.563
2.872ArgVal: 2.872 ± 0.626
0.103ArgTrp: 0.103 ± 0.051
1.846ArgTyr: 1.846 ± 0.749
0.0ArgXaa: 0.0 ± 0.0
Ser
3.693SerAla: 3.693 ± 0.513
2.462SerCys: 2.462 ± 0.613
4.513SerAsp: 4.513 ± 0.494
3.077SerGlu: 3.077 ± 0.507
4.821SerPhe: 4.821 ± 1.379
5.436SerGly: 5.436 ± 0.777
0.821SerHis: 0.821 ± 0.302
6.154SerIle: 6.154 ± 0.829
5.949SerLys: 5.949 ± 0.938
7.18SerLeu: 7.18 ± 0.931
0.923SerMet: 0.923 ± 0.344
4.821SerAsn: 4.821 ± 1.546
2.77SerPro: 2.77 ± 0.466
3.795SerGln: 3.795 ± 1.273
2.77SerArg: 2.77 ± 0.991
7.796SerSer: 7.796 ± 0.876
6.565SerThr: 6.565 ± 1.932
5.642SerVal: 5.642 ± 1.384
1.231SerTrp: 1.231 ± 0.414
2.257SerTyr: 2.257 ± 0.69
0.0SerXaa: 0.0 ± 0.0
Thr
3.385ThrAla: 3.385 ± 0.984
2.154ThrCys: 2.154 ± 0.643
2.975ThrAsp: 2.975 ± 0.887
3.18ThrGlu: 3.18 ± 0.758
2.154ThrPhe: 2.154 ± 0.34
4.206ThrGly: 4.206 ± 0.676
1.744ThrHis: 1.744 ± 0.665
4.616ThrIle: 4.616 ± 0.936
4.308ThrLys: 4.308 ± 0.544
5.334ThrLeu: 5.334 ± 1.107
0.923ThrMet: 0.923 ± 0.701
4.924ThrAsn: 4.924 ± 1.014
3.385ThrPro: 3.385 ± 0.887
3.077ThrGln: 3.077 ± 1.22
3.077ThrArg: 3.077 ± 0.596
6.052ThrSer: 6.052 ± 1.233
6.36ThrThr: 6.36 ± 0.988
4.718ThrVal: 4.718 ± 0.442
0.308ThrTrp: 0.308 ± 0.154
3.077ThrTyr: 3.077 ± 0.902
0.0ThrXaa: 0.0 ± 0.0
Val
4.206ValAla: 4.206 ± 0.88
2.051ValCys: 2.051 ± 0.663
4.924ValAsp: 4.924 ± 0.557
3.18ValGlu: 3.18 ± 1.045
2.564ValPhe: 2.564 ± 0.717
2.257ValGly: 2.257 ± 0.736
2.257ValHis: 2.257 ± 0.511
3.59ValIle: 3.59 ± 0.894
3.385ValLys: 3.385 ± 0.572
6.975ValLeu: 6.975 ± 1.218
0.513ValMet: 0.513 ± 0.157
4.924ValAsn: 4.924 ± 0.8
3.693ValPro: 3.693 ± 1.062
2.872ValGln: 2.872 ± 0.409
1.333ValArg: 1.333 ± 0.358
5.642ValSer: 5.642 ± 2.118
3.795ValThr: 3.795 ± 0.941
6.257ValVal: 6.257 ± 1.47
0.821ValTrp: 0.821 ± 0.118
3.282ValTyr: 3.282 ± 1.006
0.0ValXaa: 0.0 ± 0.0
Trp
0.513TrpAla: 0.513 ± 0.396
0.41TrpCys: 0.41 ± 0.331
0.615TrpAsp: 0.615 ± 0.185
0.513TrpGlu: 0.513 ± 0.257
0.513TrpPhe: 0.513 ± 0.257
0.205TrpGly: 0.205 ± 0.103
0.205TrpHis: 0.205 ± 0.103
0.103TrpIle: 0.103 ± 0.051
0.308TrpLys: 0.308 ± 0.154
0.821TrpLeu: 0.821 ± 0.118
0.205TrpMet: 0.205 ± 0.166
0.205TrpAsn: 0.205 ± 0.103
0.103TrpPro: 0.103 ± 0.051
0.41TrpGln: 0.41 ± 0.206
0.41TrpArg: 0.41 ± 0.143
1.026TrpSer: 1.026 ± 0.591
0.0TrpThr: 0.0 ± 0.0
0.513TrpVal: 0.513 ± 0.157
0.0TrpTrp: 0.0 ± 0.0
0.615TrpTyr: 0.615 ± 0.46
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.641TyrAla: 1.641 ± 0.341
1.333TyrCys: 1.333 ± 0.267
2.77TyrAsp: 2.77 ± 0.372
1.744TyrGlu: 1.744 ± 0.357
2.359TyrPhe: 2.359 ± 0.621
2.257TyrGly: 2.257 ± 0.361
2.462TyrHis: 2.462 ± 0.672
3.693TyrIle: 3.693 ± 0.703
3.385TyrLys: 3.385 ± 0.795
4.513TyrLeu: 4.513 ± 1.538
0.923TyrMet: 0.923 ± 0.317
4.308TyrAsn: 4.308 ± 0.6
1.949TyrPro: 1.949 ± 0.385
1.641TyrGln: 1.641 ± 0.293
1.744TyrArg: 1.744 ± 0.698
3.59TyrSer: 3.59 ± 0.493
2.872TyrThr: 2.872 ± 0.807
2.77TyrVal: 2.77 ± 1.287
0.41TyrTrp: 0.41 ± 0.206
2.564TyrTyr: 2.564 ± 1.069
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (9750 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski