Amino acid dipepetide frequency for Hubei zhaovirus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.438AlaAla: 5.438 ± 1.283
1.631AlaCys: 1.631 ± 0.75
4.35AlaAsp: 4.35 ± 0.738
1.631AlaGlu: 1.631 ± 0.511
4.35AlaPhe: 4.35 ± 0.522
4.35AlaGly: 4.35 ± 1.783
2.175AlaHis: 2.175 ± 1.522
4.894AlaIle: 4.894 ± 0.988
2.175AlaLys: 2.175 ± 0.999
4.35AlaLeu: 4.35 ± 0.522
3.263AlaMet: 3.263 ± 1.499
2.719AlaAsn: 2.719 ± 1.249
2.719AlaPro: 2.719 ± 1.249
1.631AlaGln: 1.631 ± 0.511
3.263AlaArg: 3.263 ± 0.239
4.35AlaSer: 4.35 ± 0.738
3.263AlaThr: 3.263 ± 3.543
2.719AlaVal: 2.719 ± 0.011
1.088AlaTrp: 1.088 ± 0.5
3.806AlaTyr: 3.806 ± 0.488
0.0AlaXaa: 0.0 ± 0.0
Cys
2.175CysAla: 2.175 ± 0.999
0.544CysCys: 0.544 ± 0.25
1.631CysAsp: 1.631 ± 0.75
2.175CysGlu: 2.175 ± 0.999
0.544CysPhe: 0.544 ± 0.25
0.0CysGly: 0.0 ± 0.0
0.544CysHis: 0.544 ± 0.25
0.544CysIle: 0.544 ± 0.25
1.088CysLys: 1.088 ± 0.5
1.088CysLeu: 1.088 ± 0.5
0.544CysMet: 0.544 ± 1.011
0.0CysAsn: 0.0 ± 0.0
0.544CysPro: 0.544 ± 0.25
0.0CysGln: 0.0 ± 0.0
0.544CysArg: 0.544 ± 0.25
2.175CysSer: 2.175 ± 0.261
1.088CysThr: 1.088 ± 0.5
3.806CysVal: 3.806 ± 0.488
0.0CysTrp: 0.0 ± 0.0
1.088CysTyr: 1.088 ± 0.761
0.0CysXaa: 0.0 ± 0.0
Asp
4.35AspAla: 4.35 ± 1.783
1.088AspCys: 1.088 ± 0.5
6.525AspAsp: 6.525 ± 2.998
1.631AspGlu: 1.631 ± 0.75
2.175AspPhe: 2.175 ± 0.261
3.263AspGly: 3.263 ± 0.239
0.544AspHis: 0.544 ± 0.25
2.175AspIle: 2.175 ± 0.999
5.438AspLys: 5.438 ± 1.238
1.631AspLeu: 1.631 ± 0.75
1.088AspMet: 1.088 ± 0.5
3.263AspAsn: 3.263 ± 0.239
5.438AspPro: 5.438 ± 1.238
3.263AspGln: 3.263 ± 0.239
2.719AspArg: 2.719 ± 1.249
5.438AspSer: 5.438 ± 0.023
2.719AspThr: 2.719 ± 1.249
3.263AspVal: 3.263 ± 1.022
0.544AspTrp: 0.544 ± 0.25
2.719AspTyr: 2.719 ± 0.011
0.0AspXaa: 0.0 ± 0.0
Glu
2.175GluAla: 2.175 ± 0.261
0.0GluCys: 0.0 ± 0.0
2.719GluAsp: 2.719 ± 0.011
2.175GluGlu: 2.175 ± 0.999
0.544GluPhe: 0.544 ± 0.25
1.631GluGly: 1.631 ± 0.75
1.088GluHis: 1.088 ± 0.5
3.806GluIle: 3.806 ± 0.488
3.263GluLys: 3.263 ± 1.499
2.175GluLeu: 2.175 ± 1.522
1.088GluMet: 1.088 ± 0.5
1.631GluAsn: 1.631 ± 0.511
1.088GluPro: 1.088 ± 0.761
5.438GluGln: 5.438 ± 0.023
2.719GluArg: 2.719 ± 1.249
1.631GluSer: 1.631 ± 0.511
3.263GluThr: 3.263 ± 1.499
1.631GluVal: 1.631 ± 1.772
0.0GluTrp: 0.0 ± 0.0
2.175GluTyr: 2.175 ± 0.999
0.0GluXaa: 0.0 ± 0.0
Phe
3.806PheAla: 3.806 ± 1.749
0.0PheCys: 0.0 ± 0.0
2.175PheAsp: 2.175 ± 0.261
2.175PheGlu: 2.175 ± 0.261
1.088PhePhe: 1.088 ± 0.5
1.088PheGly: 1.088 ± 0.5
1.631PheHis: 1.631 ± 0.75
3.263PheIle: 3.263 ± 2.283
0.0PheLys: 0.0 ± 0.0
2.719PheLeu: 2.719 ± 0.011
0.544PheMet: 0.544 ± 0.25
2.719PheAsn: 2.719 ± 1.249
1.631PhePro: 1.631 ± 0.511
2.175PheGln: 2.175 ± 0.261
1.631PheArg: 1.631 ± 0.511
5.438PheSer: 5.438 ± 3.805
3.263PheThr: 3.263 ± 0.239
2.719PheVal: 2.719 ± 0.011
0.0PheTrp: 0.0 ± 0.0
1.088PheTyr: 1.088 ± 0.761
0.0PheXaa: 0.0 ± 0.0
Gly
2.719GlyAla: 2.719 ± 0.011
0.544GlyCys: 0.544 ± 0.25
3.806GlyAsp: 3.806 ± 0.772
1.631GlyGlu: 1.631 ± 0.75
1.088GlyPhe: 1.088 ± 0.5
4.894GlyGly: 4.894 ± 0.988
2.175GlyHis: 2.175 ± 0.999
2.175GlyIle: 2.175 ± 1.522
4.35GlyLys: 4.35 ± 0.522
2.719GlyLeu: 2.719 ± 0.011
0.0GlyMet: 0.0 ± 0.0
3.806GlyAsn: 3.806 ± 0.488
2.175GlyPro: 2.175 ± 0.999
4.35GlyGln: 4.35 ± 0.738
3.806GlyArg: 3.806 ± 0.488
4.894GlySer: 4.894 ± 4.055
2.175GlyThr: 2.175 ± 1.522
3.806GlyVal: 3.806 ± 0.488
0.0GlyTrp: 0.0 ± 0.0
1.631GlyTyr: 1.631 ± 0.75
0.0GlyXaa: 0.0 ± 0.0
His
1.631HisAla: 1.631 ± 0.75
0.544HisCys: 0.544 ± 0.25
2.175HisAsp: 2.175 ± 0.999
2.719HisGlu: 2.719 ± 0.011
1.631HisPhe: 1.631 ± 0.511
0.544HisGly: 0.544 ± 0.25
0.544HisHis: 0.544 ± 0.25
2.175HisIle: 2.175 ± 0.999
0.544HisLys: 0.544 ± 1.011
1.631HisLeu: 1.631 ± 0.511
0.544HisMet: 0.544 ± 0.25
1.088HisAsn: 1.088 ± 0.5
1.088HisPro: 1.088 ± 0.5
3.263HisGln: 3.263 ± 1.499
2.719HisArg: 2.719 ± 1.249
3.806HisSer: 3.806 ± 0.488
0.544HisThr: 0.544 ± 1.011
2.175HisVal: 2.175 ± 0.999
0.544HisTrp: 0.544 ± 0.25
0.544HisTyr: 0.544 ± 0.25
0.0HisXaa: 0.0 ± 0.0
Ile
4.894IleAla: 4.894 ± 2.794
0.544IleCys: 0.544 ± 0.25
2.175IleAsp: 2.175 ± 0.999
3.263IleGlu: 3.263 ± 1.022
2.175IlePhe: 2.175 ± 0.999
2.175IleGly: 2.175 ± 0.261
3.806IleHis: 3.806 ± 1.749
2.175IleIle: 2.175 ± 0.999
3.263IleLys: 3.263 ± 1.022
1.631IleLeu: 1.631 ± 0.511
1.088IleMet: 1.088 ± 0.761
2.719IleAsn: 2.719 ± 0.011
1.631IlePro: 1.631 ± 1.772
4.894IleGln: 4.894 ± 0.988
2.175IleArg: 2.175 ± 0.261
1.631IleSer: 1.631 ± 0.511
2.719IleThr: 2.719 ± 0.011
4.894IleVal: 4.894 ± 2.249
1.088IleTrp: 1.088 ± 0.5
2.175IleTyr: 2.175 ± 0.261
0.0IleXaa: 0.0 ± 0.0
Lys
1.088LysAla: 1.088 ± 0.5
0.544LysCys: 0.544 ± 0.25
2.719LysAsp: 2.719 ± 1.249
2.175LysGlu: 2.175 ± 0.999
2.175LysPhe: 2.175 ± 1.522
5.438LysGly: 5.438 ± 1.238
2.175LysHis: 2.175 ± 1.522
3.263LysIle: 3.263 ± 1.022
2.175LysLys: 2.175 ± 0.999
2.719LysLeu: 2.719 ± 0.011
3.263LysMet: 3.263 ± 1.393
3.263LysAsn: 3.263 ± 1.499
2.719LysPro: 2.719 ± 1.272
5.438LysGln: 5.438 ± 0.023
4.35LysArg: 4.35 ± 0.738
5.438LysSer: 5.438 ± 0.023
4.35LysThr: 4.35 ± 0.738
2.175LysVal: 2.175 ± 1.522
1.088LysTrp: 1.088 ± 0.5
2.719LysTyr: 2.719 ± 2.533
0.0LysXaa: 0.0 ± 0.0
Leu
3.263LeuAla: 3.263 ± 1.499
0.544LeuCys: 0.544 ± 1.011
2.719LeuAsp: 2.719 ± 1.249
2.719LeuGlu: 2.719 ± 1.272
1.088LeuPhe: 1.088 ± 0.761
3.263LeuGly: 3.263 ± 0.239
2.719LeuHis: 2.719 ± 0.011
2.175LeuIle: 2.175 ± 0.261
3.806LeuLys: 3.806 ± 1.749
3.806LeuLeu: 3.806 ± 0.772
2.175LeuMet: 2.175 ± 0.795
4.894LeuAsn: 4.894 ± 0.272
2.719LeuPro: 2.719 ± 1.249
3.263LeuGln: 3.263 ± 0.239
4.35LeuArg: 4.35 ± 0.522
6.525LeuSer: 6.525 ± 0.784
4.894LeuThr: 4.894 ± 1.533
3.806LeuVal: 3.806 ± 1.749
0.544LeuTrp: 0.544 ± 1.011
2.719LeuTyr: 2.719 ± 2.533
0.0LeuXaa: 0.0 ± 0.0
Met
1.088MetAla: 1.088 ± 0.5
1.088MetCys: 1.088 ± 0.5
0.544MetAsp: 0.544 ± 0.25
2.175MetGlu: 2.175 ± 0.999
1.088MetPhe: 1.088 ± 0.5
0.544MetGly: 0.544 ± 0.25
0.544MetHis: 0.544 ± 0.25
0.544MetIle: 0.544 ± 0.25
2.175MetLys: 2.175 ± 0.261
3.263MetLeu: 3.263 ± 1.499
1.088MetMet: 1.088 ± 0.5
1.088MetAsn: 1.088 ± 0.761
0.544MetPro: 0.544 ± 1.011
1.088MetGln: 1.088 ± 0.5
1.631MetArg: 1.631 ± 0.75
1.631MetSer: 1.631 ± 0.75
3.806MetThr: 3.806 ± 2.033
1.088MetVal: 1.088 ± 0.5
0.0MetTrp: 0.0 ± 0.0
1.631MetTyr: 1.631 ± 0.75
0.0MetXaa: 0.0 ± 0.0
Asn
3.806AsnAla: 3.806 ± 0.772
1.631AsnCys: 1.631 ± 0.75
3.263AsnAsp: 3.263 ± 1.499
0.544AsnGlu: 0.544 ± 0.25
3.263AsnPhe: 3.263 ± 0.239
2.719AsnGly: 2.719 ± 1.249
1.088AsnHis: 1.088 ± 0.5
3.263AsnIle: 3.263 ± 1.499
4.894AsnLys: 4.894 ± 2.249
2.719AsnLeu: 2.719 ± 1.272
1.088AsnMet: 1.088 ± 0.5
3.806AsnAsn: 3.806 ± 1.749
2.719AsnPro: 2.719 ± 0.011
3.806AsnGln: 3.806 ± 2.033
3.806AsnArg: 3.806 ± 1.749
3.263AsnSer: 3.263 ± 1.022
4.894AsnThr: 4.894 ± 0.988
2.719AsnVal: 2.719 ± 1.249
0.544AsnTrp: 0.544 ± 0.25
3.263AsnTyr: 3.263 ± 0.239
0.0AsnXaa: 0.0 ± 0.0
Pro
0.544ProAla: 0.544 ± 0.25
0.544ProCys: 0.544 ± 0.25
2.719ProAsp: 2.719 ± 1.249
0.544ProGlu: 0.544 ± 0.25
0.544ProPhe: 0.544 ± 0.25
2.175ProGly: 2.175 ± 1.522
1.631ProHis: 1.631 ± 0.75
1.088ProIle: 1.088 ± 0.5
2.719ProLys: 2.719 ± 1.249
2.719ProLeu: 2.719 ± 1.249
0.0ProMet: 0.0 ± 0.0
2.719ProAsn: 2.719 ± 0.011
1.088ProPro: 1.088 ± 0.5
2.175ProGln: 2.175 ± 0.261
3.806ProArg: 3.806 ± 0.772
2.719ProSer: 2.719 ± 0.011
3.806ProThr: 3.806 ± 0.772
3.806ProVal: 3.806 ± 2.033
1.088ProTrp: 1.088 ± 0.761
4.35ProTyr: 4.35 ± 0.522
0.0ProXaa: 0.0 ± 0.0
Gln
3.263GlnAla: 3.263 ± 1.499
2.719GlnCys: 2.719 ± 1.249
1.631GlnAsp: 1.631 ± 0.75
3.806GlnGlu: 3.806 ± 1.749
3.263GlnPhe: 3.263 ± 1.022
3.806GlnGly: 3.806 ± 0.488
2.175GlnHis: 2.175 ± 0.999
2.175GlnIle: 2.175 ± 0.999
1.631GlnLys: 1.631 ± 0.75
4.35GlnLeu: 4.35 ± 0.522
0.0GlnMet: 0.0 ± 0.0
5.438GlnAsn: 5.438 ± 0.023
3.263GlnPro: 3.263 ± 0.239
2.719GlnGln: 2.719 ± 0.011
1.631GlnArg: 1.631 ± 0.75
7.069GlnSer: 7.069 ± 0.534
5.982GlnThr: 5.982 ± 3.555
3.806GlnVal: 3.806 ± 3.294
0.0GlnTrp: 0.0 ± 0.0
3.263GlnTyr: 3.263 ± 1.022
0.0GlnXaa: 0.0 ± 0.0
Arg
4.35ArgAla: 4.35 ± 0.522
1.088ArgCys: 1.088 ± 0.761
3.806ArgAsp: 3.806 ± 1.749
0.544ArgGlu: 0.544 ± 0.25
3.263ArgPhe: 3.263 ± 0.239
2.719ArgGly: 2.719 ± 1.249
0.544ArgHis: 0.544 ± 0.25
1.088ArgIle: 1.088 ± 0.5
5.438ArgLys: 5.438 ± 2.544
3.263ArgLeu: 3.263 ± 0.239
4.894ArgMet: 4.894 ± 0.988
3.806ArgAsn: 3.806 ± 1.749
2.175ArgPro: 2.175 ± 0.261
5.438ArgGln: 5.438 ± 0.023
3.806ArgArg: 3.806 ± 0.772
4.35ArgSer: 4.35 ± 0.522
3.806ArgThr: 3.806 ± 0.488
2.175ArgVal: 2.175 ± 0.999
0.544ArgTrp: 0.544 ± 0.25
3.263ArgTyr: 3.263 ± 1.499
0.0ArgXaa: 0.0 ± 0.0
Ser
8.157SerAla: 8.157 ± 0.034
1.631SerCys: 1.631 ± 0.75
5.438SerAsp: 5.438 ± 0.023
2.175SerGlu: 2.175 ± 0.261
3.263SerPhe: 3.263 ± 1.022
7.069SerGly: 7.069 ± 1.794
3.806SerHis: 3.806 ± 0.488
4.35SerIle: 4.35 ± 0.738
4.35SerLys: 4.35 ± 4.304
8.7SerLeu: 8.7 ± 2.305
1.631SerMet: 1.631 ± 0.75
3.806SerAsn: 3.806 ± 0.488
3.263SerPro: 3.263 ± 1.022
3.806SerGln: 3.806 ± 0.772
7.069SerArg: 7.069 ± 1.794
5.438SerSer: 5.438 ± 0.023
1.631SerThr: 1.631 ± 0.511
3.263SerVal: 3.263 ± 2.283
0.544SerTrp: 0.544 ± 0.25
3.806SerTyr: 3.806 ± 0.488
0.0SerXaa: 0.0 ± 0.0
Thr
1.631ThrAla: 1.631 ± 0.511
2.719ThrCys: 2.719 ± 0.011
2.175ThrAsp: 2.175 ± 0.261
5.438ThrGlu: 5.438 ± 0.023
3.263ThrPhe: 3.263 ± 1.022
2.175ThrGly: 2.175 ± 0.261
0.0ThrHis: 0.0 ± 0.0
3.263ThrIle: 3.263 ± 2.283
5.982ThrLys: 5.982 ± 1.033
3.263ThrLeu: 3.263 ± 0.239
1.631ThrMet: 1.631 ± 0.511
6.525ThrAsn: 6.525 ± 1.738
0.544ThrPro: 0.544 ± 0.25
3.806ThrGln: 3.806 ± 0.772
3.806ThrArg: 3.806 ± 0.772
5.438ThrSer: 5.438 ± 2.544
5.982ThrThr: 5.982 ± 4.815
5.438ThrVal: 5.438 ± 2.544
0.544ThrTrp: 0.544 ± 0.25
3.263ThrTyr: 3.263 ± 2.283
0.0ThrXaa: 0.0 ± 0.0
Val
5.438ValAla: 5.438 ± 1.283
1.631ValCys: 1.631 ± 0.511
4.35ValAsp: 4.35 ± 1.783
0.0ValGlu: 0.0 ± 0.0
0.544ValPhe: 0.544 ± 1.011
3.806ValGly: 3.806 ± 3.294
3.263ValHis: 3.263 ± 1.499
4.35ValIle: 4.35 ± 0.522
3.806ValLys: 3.806 ± 0.488
5.982ValLeu: 5.982 ± 1.488
0.544ValMet: 0.544 ± 0.25
2.719ValAsn: 2.719 ± 1.249
4.35ValPro: 4.35 ± 0.522
3.263ValGln: 3.263 ± 0.239
3.806ValArg: 3.806 ± 0.488
5.438ValSer: 5.438 ± 0.023
2.175ValThr: 2.175 ± 2.783
4.35ValVal: 4.35 ± 0.738
1.088ValTrp: 1.088 ± 0.5
4.35ValTyr: 4.35 ± 1.999
0.0ValXaa: 0.0 ± 0.0
Trp
0.544TrpAla: 0.544 ± 0.25
0.544TrpCys: 0.544 ± 0.25
0.544TrpAsp: 0.544 ± 0.25
0.0TrpGlu: 0.0 ± 0.0
1.088TrpPhe: 1.088 ± 0.5
0.544TrpGly: 0.544 ± 0.25
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.544TrpLeu: 0.544 ± 1.011
0.0TrpMet: 0.0 ± 0.0
0.544TrpAsn: 0.544 ± 0.25
0.0TrpPro: 0.0 ± 0.0
1.088TrpGln: 1.088 ± 0.761
0.0TrpArg: 0.0 ± 0.0
2.719TrpSer: 2.719 ± 1.249
0.544TrpThr: 0.544 ± 0.25
0.544TrpVal: 0.544 ± 0.25
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.806TyrAla: 3.806 ± 0.488
0.544TyrCys: 0.544 ± 0.25
3.806TyrAsp: 3.806 ± 2.033
2.719TyrGlu: 2.719 ± 1.272
2.719TyrPhe: 2.719 ± 0.011
0.544TyrGly: 0.544 ± 0.25
0.0TyrHis: 0.0 ± 0.0
4.35TyrIle: 4.35 ± 1.783
2.175TyrLys: 2.175 ± 0.261
3.263TyrLeu: 3.263 ± 1.022
1.631TyrMet: 1.631 ± 0.75
0.544TyrAsn: 0.544 ± 1.011
1.088TyrPro: 1.088 ± 0.5
1.088TyrGln: 1.088 ± 0.5
2.719TyrArg: 2.719 ± 1.249
3.806TyrSer: 3.806 ± 0.772
5.982TyrThr: 5.982 ± 1.033
7.069TyrVal: 7.069 ± 1.988
0.0TyrTrp: 0.0 ± 0.0
2.175TyrTyr: 2.175 ± 0.261
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1840 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski