Amino acid dipepetide frequency for Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.679AlaAla: 12.679 ± 2.21
0.987AlaCys: 0.987 ± 0.302
2.961AlaAsp: 2.961 ± 0.57
3.796AlaGlu: 3.796 ± 0.672
2.733AlaPhe: 2.733 ± 0.416
4.631AlaGly: 4.631 ± 0.765
1.746AlaHis: 1.746 ± 0.351
3.948AlaIle: 3.948 ± 0.577
1.443AlaLys: 1.443 ± 0.322
7.972AlaLeu: 7.972 ± 0.877
1.518AlaMet: 1.518 ± 0.373
2.506AlaAsn: 2.506 ± 0.676
7.517AlaPro: 7.517 ± 0.856
2.733AlaGln: 2.733 ± 0.471
7.668AlaArg: 7.668 ± 1.086
6.529AlaSer: 6.529 ± 0.745
4.783AlaThr: 4.783 ± 0.588
5.618AlaVal: 5.618 ± 0.898
1.291AlaTrp: 1.291 ± 0.348
2.126AlaTyr: 2.126 ± 0.382
0.0AlaXaa: 0.0 ± 0.0
Cys
1.822CysAla: 1.822 ± 0.403
1.063CysCys: 1.063 ± 0.304
0.759CysAsp: 0.759 ± 0.217
0.683CysGlu: 0.683 ± 0.21
0.531CysPhe: 0.531 ± 0.162
1.822CysGly: 1.822 ± 0.409
0.911CysHis: 0.911 ± 0.378
0.759CysIle: 0.759 ± 0.25
0.759CysLys: 0.759 ± 0.204
1.443CysLeu: 1.443 ± 0.358
0.38CysMet: 0.38 ± 0.162
1.063CysAsn: 1.063 ± 0.294
0.835CysPro: 0.835 ± 0.295
0.152CysGln: 0.152 ± 0.103
1.139CysArg: 1.139 ± 0.296
1.443CysSer: 1.443 ± 0.422
1.139CysThr: 1.139 ± 0.395
1.063CysVal: 1.063 ± 0.278
0.304CysTrp: 0.304 ± 0.165
0.987CysTyr: 0.987 ± 0.28
0.0CysXaa: 0.0 ± 0.0
Asp
4.328AspAla: 4.328 ± 0.71
0.683AspCys: 0.683 ± 0.237
2.581AspAsp: 2.581 ± 0.535
3.796AspGlu: 3.796 ± 0.8
1.518AspPhe: 1.518 ± 0.366
2.506AspGly: 2.506 ± 0.475
0.911AspHis: 0.911 ± 0.321
1.67AspIle: 1.67 ± 0.25
1.594AspLys: 1.594 ± 0.333
5.315AspLeu: 5.315 ± 0.743
2.05AspMet: 2.05 ± 0.41
1.67AspAsn: 1.67 ± 0.424
2.43AspPro: 2.43 ± 0.473
1.518AspGln: 1.518 ± 0.304
3.493AspArg: 3.493 ± 0.639
3.493AspSer: 3.493 ± 0.528
2.809AspThr: 2.809 ± 0.667
3.341AspVal: 3.341 ± 0.484
0.683AspTrp: 0.683 ± 0.189
2.278AspTyr: 2.278 ± 0.357
0.0AspXaa: 0.0 ± 0.0
Glu
4.783GluAla: 4.783 ± 0.667
1.367GluCys: 1.367 ± 0.318
4.555GluAsp: 4.555 ± 0.707
8.504GluGlu: 8.504 ± 1.275
1.67GluPhe: 1.67 ± 0.294
3.872GluGly: 3.872 ± 0.615
1.291GluHis: 1.291 ± 0.289
2.202GluIle: 2.202 ± 0.492
1.822GluLys: 1.822 ± 0.381
4.631GluLeu: 4.631 ± 0.643
1.215GluMet: 1.215 ± 0.246
1.67GluAsn: 1.67 ± 0.444
3.72GluPro: 3.72 ± 1.046
3.113GluGln: 3.113 ± 0.39
4.555GluArg: 4.555 ± 0.785
2.809GluSer: 2.809 ± 0.478
3.341GluThr: 3.341 ± 0.493
3.644GluVal: 3.644 ± 0.423
0.607GluTrp: 0.607 ± 0.224
1.139GluTyr: 1.139 ± 0.309
0.0GluXaa: 0.0 ± 0.0
Phe
2.43PheAla: 2.43 ± 0.401
0.835PheCys: 0.835 ± 0.29
1.898PheAsp: 1.898 ± 0.516
1.898PheGlu: 1.898 ± 0.354
1.215PhePhe: 1.215 ± 0.335
1.291PheGly: 1.291 ± 0.324
0.38PheHis: 0.38 ± 0.148
1.367PheIle: 1.367 ± 0.36
1.215PheLys: 1.215 ± 0.382
3.113PheLeu: 3.113 ± 0.576
1.291PheMet: 1.291 ± 0.266
1.367PheAsn: 1.367 ± 0.248
2.506PhePro: 2.506 ± 0.505
1.443PheGln: 1.443 ± 0.273
2.581PheArg: 2.581 ± 0.409
2.506PheSer: 2.506 ± 0.432
2.126PheThr: 2.126 ± 0.48
2.506PheVal: 2.506 ± 0.476
0.152PheTrp: 0.152 ± 0.11
1.443PheTyr: 1.443 ± 0.338
0.0PheXaa: 0.0 ± 0.0
Gly
5.087GlyAla: 5.087 ± 0.757
1.215GlyCys: 1.215 ± 0.341
3.113GlyAsp: 3.113 ± 0.505
2.809GlyGlu: 2.809 ± 0.406
2.43GlyPhe: 2.43 ± 0.367
7.061GlyGly: 7.061 ± 0.989
2.126GlyHis: 2.126 ± 0.402
2.581GlyIle: 2.581 ± 0.485
1.746GlyLys: 1.746 ± 0.469
4.859GlyLeu: 4.859 ± 0.599
1.594GlyMet: 1.594 ± 0.397
2.885GlyAsn: 2.885 ± 0.605
3.796GlyPro: 3.796 ± 0.685
2.809GlyGln: 2.809 ± 0.487
5.391GlyArg: 5.391 ± 0.798
5.391GlySer: 5.391 ± 0.814
2.961GlyThr: 2.961 ± 0.442
4.631GlyVal: 4.631 ± 0.706
0.607GlyTrp: 0.607 ± 0.244
1.367GlyTyr: 1.367 ± 0.368
0.0GlyXaa: 0.0 ± 0.0
His
1.518HisAla: 1.518 ± 0.284
0.683HisCys: 0.683 ± 0.297
0.759HisAsp: 0.759 ± 0.254
1.215HisGlu: 1.215 ± 0.315
0.607HisPhe: 0.607 ± 0.245
2.202HisGly: 2.202 ± 0.375
0.759HisHis: 0.759 ± 0.239
0.911HisIle: 0.911 ± 0.265
0.835HisLys: 0.835 ± 0.282
2.809HisLeu: 2.809 ± 0.431
0.152HisMet: 0.152 ± 0.123
1.139HisAsn: 1.139 ± 0.276
1.974HisPro: 1.974 ± 0.365
0.911HisGln: 0.911 ± 0.255
2.43HisArg: 2.43 ± 0.435
1.67HisSer: 1.67 ± 0.458
0.911HisThr: 0.911 ± 0.184
1.139HisVal: 1.139 ± 0.272
0.304HisTrp: 0.304 ± 0.146
0.607HisTyr: 0.607 ± 0.193
0.0HisXaa: 0.0 ± 0.0
Ile
2.657IleAla: 2.657 ± 0.455
0.835IleCys: 0.835 ± 0.241
1.67IleAsp: 1.67 ± 0.354
1.746IleGlu: 1.746 ± 0.376
1.367IlePhe: 1.367 ± 0.378
2.202IleGly: 2.202 ± 0.594
0.835IleHis: 0.835 ± 0.239
1.974IleIle: 1.974 ± 0.44
2.581IleLys: 2.581 ± 0.497
3.568IleLeu: 3.568 ± 0.532
0.683IleMet: 0.683 ± 0.198
2.43IleAsn: 2.43 ± 0.528
2.202IlePro: 2.202 ± 0.637
1.063IleGln: 1.063 ± 0.27
2.354IleArg: 2.354 ± 0.539
3.113IleSer: 3.113 ± 0.534
2.43IleThr: 2.43 ± 0.556
2.278IleVal: 2.278 ± 0.436
0.531IleTrp: 0.531 ± 0.183
0.911IleTyr: 0.911 ± 0.255
0.0IleXaa: 0.0 ± 0.0
Lys
1.898LysAla: 1.898 ± 0.429
0.683LysCys: 0.683 ± 0.224
1.67LysAsp: 1.67 ± 0.322
1.822LysGlu: 1.822 ± 0.454
1.215LysPhe: 1.215 ± 0.369
1.974LysGly: 1.974 ± 0.5
0.607LysHis: 0.607 ± 0.302
2.278LysIle: 2.278 ± 0.412
3.113LysLys: 3.113 ± 0.677
3.568LysLeu: 3.568 ± 0.667
0.987LysMet: 0.987 ± 0.348
1.139LysAsn: 1.139 ± 0.271
1.822LysPro: 1.822 ± 0.429
1.139LysGln: 1.139 ± 0.324
3.265LysArg: 3.265 ± 0.702
2.202LysSer: 2.202 ± 0.443
2.354LysThr: 2.354 ± 0.483
1.594LysVal: 1.594 ± 0.305
0.228LysTrp: 0.228 ± 0.174
1.215LysTyr: 1.215 ± 0.262
0.0LysXaa: 0.0 ± 0.0
Leu
7.744LeuAla: 7.744 ± 0.672
1.443LeuCys: 1.443 ± 0.348
5.694LeuAsp: 5.694 ± 0.588
4.631LeuGlu: 4.631 ± 0.698
1.746LeuPhe: 1.746 ± 0.319
4.555LeuGly: 4.555 ± 0.589
2.885LeuHis: 2.885 ± 0.463
3.341LeuIle: 3.341 ± 0.61
4.631LeuLys: 4.631 ± 0.734
8.579LeuLeu: 8.579 ± 0.936
2.506LeuMet: 2.506 ± 0.422
4.252LeuAsn: 4.252 ± 0.569
5.846LeuPro: 5.846 ± 0.758
4.328LeuGln: 4.328 ± 0.783
7.517LeuArg: 7.517 ± 1.042
5.77LeuSer: 5.77 ± 0.722
6.302LeuThr: 6.302 ± 0.896
4.48LeuVal: 4.48 ± 0.584
1.67LeuTrp: 1.67 ± 0.352
2.657LeuTyr: 2.657 ± 0.547
0.0LeuXaa: 0.0 ± 0.0
Met
2.278MetAla: 2.278 ± 0.459
0.304MetCys: 0.304 ± 0.139
0.911MetAsp: 0.911 ± 0.226
1.822MetGlu: 1.822 ± 0.362
0.987MetPhe: 0.987 ± 0.262
1.291MetGly: 1.291 ± 0.258
0.987MetHis: 0.987 ± 0.402
0.911MetIle: 0.911 ± 0.294
0.531MetLys: 0.531 ± 0.174
2.354MetLeu: 2.354 ± 0.436
0.987MetMet: 0.987 ± 0.238
0.683MetAsn: 0.683 ± 0.267
1.443MetPro: 1.443 ± 0.297
0.911MetGln: 0.911 ± 0.308
1.974MetArg: 1.974 ± 0.534
1.67MetSer: 1.67 ± 0.316
1.822MetThr: 1.822 ± 0.371
1.746MetVal: 1.746 ± 0.383
0.38MetTrp: 0.38 ± 0.177
0.683MetTyr: 0.683 ± 0.222
0.0MetXaa: 0.0 ± 0.0
Asn
2.733AsnAla: 2.733 ± 0.751
0.759AsnCys: 0.759 ± 0.318
1.898AsnAsp: 1.898 ± 0.54
2.278AsnGlu: 2.278 ± 0.314
2.05AsnPhe: 2.05 ± 0.46
1.746AsnGly: 1.746 ± 0.516
0.759AsnHis: 0.759 ± 0.302
1.974AsnIle: 1.974 ± 0.421
1.139AsnLys: 1.139 ± 0.292
4.404AsnLeu: 4.404 ± 0.521
1.518AsnMet: 1.518 ± 0.371
1.746AsnAsn: 1.746 ± 0.526
2.961AsnPro: 2.961 ± 0.553
1.215AsnGln: 1.215 ± 0.26
2.506AsnArg: 2.506 ± 0.431
3.568AsnSer: 3.568 ± 0.613
2.202AsnThr: 2.202 ± 0.471
2.05AsnVal: 2.05 ± 0.397
0.531AsnTrp: 0.531 ± 0.225
1.67AsnTyr: 1.67 ± 0.406
0.0AsnXaa: 0.0 ± 0.0
Pro
5.922ProAla: 5.922 ± 0.875
0.759ProCys: 0.759 ± 0.208
3.493ProAsp: 3.493 ± 0.362
5.391ProGlu: 5.391 ± 1.274
2.961ProPhe: 2.961 ± 0.562
5.315ProGly: 5.315 ± 0.624
0.911ProHis: 0.911 ± 0.24
1.974ProIle: 1.974 ± 0.347
2.278ProLys: 2.278 ± 0.388
5.618ProLeu: 5.618 ± 0.777
1.518ProMet: 1.518 ± 0.305
2.657ProAsn: 2.657 ± 0.454
10.25ProPro: 10.25 ± 1.531
2.278ProGln: 2.278 ± 0.59
6.529ProArg: 6.529 ± 1.015
5.922ProSer: 5.922 ± 0.726
5.239ProThr: 5.239 ± 0.659
4.935ProVal: 4.935 ± 0.928
0.835ProTrp: 0.835 ± 0.308
1.746ProTyr: 1.746 ± 0.357
0.0ProXaa: 0.0 ± 0.0
Gln
3.796GlnAla: 3.796 ± 0.473
0.531GlnCys: 0.531 ± 0.202
1.746GlnAsp: 1.746 ± 0.322
3.189GlnGlu: 3.189 ± 0.558
1.139GlnPhe: 1.139 ± 0.307
2.354GlnGly: 2.354 ± 0.378
0.911GlnHis: 0.911 ± 0.245
1.443GlnIle: 1.443 ± 0.259
1.367GlnLys: 1.367 ± 0.296
3.113GlnLeu: 3.113 ± 0.497
0.835GlnMet: 0.835 ± 0.239
1.746GlnAsn: 1.746 ± 0.458
4.024GlnPro: 4.024 ± 0.49
2.885GlnGln: 2.885 ± 0.461
3.189GlnArg: 3.189 ± 0.539
2.733GlnSer: 2.733 ± 0.488
2.202GlnThr: 2.202 ± 0.388
2.733GlnVal: 2.733 ± 0.381
0.38GlnTrp: 0.38 ± 0.178
0.683GlnTyr: 0.683 ± 0.218
0.0GlnXaa: 0.0 ± 0.0
Arg
8.276ArgAla: 8.276 ± 1.147
1.67ArgCys: 1.67 ± 0.51
4.024ArgAsp: 4.024 ± 0.785
3.948ArgGlu: 3.948 ± 0.732
2.278ArgPhe: 2.278 ± 0.429
6.15ArgGly: 6.15 ± 0.8
2.657ArgHis: 2.657 ± 0.562
1.822ArgIle: 1.822 ± 0.363
2.126ArgLys: 2.126 ± 0.449
6.605ArgLeu: 6.605 ± 0.952
1.215ArgMet: 1.215 ± 0.374
3.644ArgAsn: 3.644 ± 0.492
6.833ArgPro: 6.833 ± 0.989
4.024ArgGln: 4.024 ± 0.604
12.376ArgArg: 12.376 ± 2.381
6.226ArgSer: 6.226 ± 1.113
3.265ArgThr: 3.265 ± 0.572
4.252ArgVal: 4.252 ± 0.754
0.987ArgTrp: 0.987 ± 0.234
1.443ArgTyr: 1.443 ± 0.256
0.0ArgXaa: 0.0 ± 0.0
Ser
5.011SerAla: 5.011 ± 0.803
1.67SerCys: 1.67 ± 0.399
2.733SerAsp: 2.733 ± 0.423
4.1SerGlu: 4.1 ± 0.672
2.278SerPhe: 2.278 ± 0.421
6.985SerGly: 6.985 ± 0.952
1.518SerHis: 1.518 ± 0.403
2.733SerIle: 2.733 ± 0.448
2.506SerLys: 2.506 ± 0.425
6.529SerLeu: 6.529 ± 0.763
1.594SerMet: 1.594 ± 0.403
2.657SerAsn: 2.657 ± 0.525
6.605SerPro: 6.605 ± 0.955
3.265SerGln: 3.265 ± 0.475
5.163SerArg: 5.163 ± 0.76
6.605SerSer: 6.605 ± 1.185
4.859SerThr: 4.859 ± 0.74
4.252SerVal: 4.252 ± 0.547
1.215SerTrp: 1.215 ± 0.321
1.974SerTyr: 1.974 ± 0.601
0.0SerXaa: 0.0 ± 0.0
Thr
4.48ThrAla: 4.48 ± 0.623
1.367ThrCys: 1.367 ± 0.37
2.278ThrAsp: 2.278 ± 0.437
3.037ThrGlu: 3.037 ± 0.402
2.657ThrPhe: 2.657 ± 0.623
4.176ThrGly: 4.176 ± 0.821
1.291ThrHis: 1.291 ± 0.294
1.746ThrIle: 1.746 ± 0.505
1.898ThrLys: 1.898 ± 0.743
5.77ThrLeu: 5.77 ± 0.659
1.443ThrMet: 1.443 ± 0.278
1.898ThrAsn: 1.898 ± 0.488
4.935ThrPro: 4.935 ± 0.722
2.354ThrGln: 2.354 ± 0.379
4.252ThrArg: 4.252 ± 0.654
4.1ThrSer: 4.1 ± 0.727
4.631ThrThr: 4.631 ± 0.646
4.707ThrVal: 4.707 ± 0.793
0.759ThrTrp: 0.759 ± 0.23
1.974ThrTyr: 1.974 ± 0.439
0.0ThrXaa: 0.0 ± 0.0
Val
5.467ValAla: 5.467 ± 0.68
1.443ValCys: 1.443 ± 0.334
3.037ValAsp: 3.037 ± 0.63
3.493ValGlu: 3.493 ± 0.517
2.278ValPhe: 2.278 ± 0.539
2.354ValGly: 2.354 ± 0.358
0.911ValHis: 0.911 ± 0.305
2.43ValIle: 2.43 ± 0.487
1.139ValLys: 1.139 ± 0.312
5.846ValLeu: 5.846 ± 0.617
1.974ValMet: 1.974 ± 0.375
2.126ValAsn: 2.126 ± 0.389
4.631ValPro: 4.631 ± 0.598
2.885ValGln: 2.885 ± 0.551
4.707ValArg: 4.707 ± 0.64
5.087ValSer: 5.087 ± 0.814
4.1ValThr: 4.1 ± 0.522
4.707ValVal: 4.707 ± 0.734
0.607ValTrp: 0.607 ± 0.255
2.43ValTyr: 2.43 ± 0.473
0.0ValXaa: 0.0 ± 0.0
Trp
0.531TrpAla: 0.531 ± 0.186
0.152TrpCys: 0.152 ± 0.121
0.835TrpAsp: 0.835 ± 0.353
0.911TrpGlu: 0.911 ± 0.222
0.531TrpPhe: 0.531 ± 0.183
0.759TrpGly: 0.759 ± 0.22
0.076TrpHis: 0.076 ± 0.089
0.304TrpIle: 0.304 ± 0.134
0.683TrpLys: 0.683 ± 0.243
1.139TrpLeu: 1.139 ± 0.282
0.304TrpMet: 0.304 ± 0.15
1.063TrpAsn: 1.063 ± 0.323
1.063TrpPro: 1.063 ± 0.338
0.456TrpGln: 0.456 ± 0.207
1.063TrpArg: 1.063 ± 0.29
1.215TrpSer: 1.215 ± 0.281
0.835TrpThr: 0.835 ± 0.247
0.456TrpVal: 0.456 ± 0.19
0.228TrpTrp: 0.228 ± 0.13
0.228TrpTyr: 0.228 ± 0.155
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.746TyrAla: 1.746 ± 0.44
0.607TyrCys: 0.607 ± 0.233
2.05TyrAsp: 2.05 ± 0.394
1.443TyrGlu: 1.443 ± 0.322
1.367TyrPhe: 1.367 ± 0.307
1.215TyrGly: 1.215 ± 0.371
1.063TyrHis: 1.063 ± 0.26
1.063TyrIle: 1.063 ± 0.289
1.367TyrLys: 1.367 ± 0.379
3.341TyrLeu: 3.341 ± 0.588
0.835TyrMet: 0.835 ± 0.327
1.367TyrAsn: 1.367 ± 0.428
1.139TyrPro: 1.139 ± 0.298
1.518TyrGln: 1.518 ± 0.353
1.67TyrArg: 1.67 ± 0.305
2.278TyrSer: 2.278 ± 0.532
1.443TyrThr: 1.443 ± 0.295
1.518TyrVal: 1.518 ± 0.331
0.531TyrTrp: 0.531 ± 0.179
0.456TyrTyr: 0.456 ± 0.236
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 47 proteins (13172 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski