Amino acid dipepetide frequency for Beihai barnacle virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.641AlaAla: 10.641 ± 2.496
1.038AlaCys: 1.038 ± 0.433
3.893AlaAsp: 3.893 ± 1.02
6.488AlaGlu: 6.488 ± 1.551
1.557AlaPhe: 1.557 ± 0.262
7.527AlaGly: 7.527 ± 0.753
2.855AlaHis: 2.855 ± 1.171
3.114AlaIle: 3.114 ± 0.887
4.672AlaLys: 4.672 ± 1.828
12.198AlaLeu: 12.198 ± 1.739
2.076AlaMet: 2.076 ± 0.765
2.595AlaAsn: 2.595 ± 1.045
5.45AlaPro: 5.45 ± 0.495
3.893AlaGln: 3.893 ± 1.221
4.412AlaArg: 4.412 ± 1.664
10.122AlaSer: 10.122 ± 0.083
3.634AlaThr: 3.634 ± 2.209
6.229AlaVal: 6.229 ± 1.371
1.557AlaTrp: 1.557 ± 0.832
2.336AlaTyr: 2.336 ± 0.241
0.0AlaXaa: 0.0 ± 0.0
Cys
1.557CysAla: 1.557 ± 0.827
0.0CysCys: 0.0 ± 0.0
0.779CysAsp: 0.779 ± 0.582
1.298CysGlu: 1.298 ± 0.513
0.0CysPhe: 0.0 ± 0.0
0.26CysGly: 0.26 ± 0.297
0.0CysHis: 0.0 ± 0.0
0.519CysIle: 0.519 ± 0.466
0.779CysLys: 0.779 ± 0.75
1.298CysLeu: 1.298 ± 0.373
0.779CysMet: 0.779 ± 0.328
0.519CysAsn: 0.519 ± 0.58
0.519CysPro: 0.519 ± 0.466
0.779CysGln: 0.779 ± 0.428
2.336CysArg: 2.336 ± 1.219
1.557CysSer: 1.557 ± 0.517
0.779CysThr: 0.779 ± 0.414
0.519CysVal: 0.519 ± 0.276
0.0CysTrp: 0.0 ± 0.0
0.779CysTyr: 0.779 ± 0.328
0.0CysXaa: 0.0 ± 0.0
Asp
4.153AspAla: 4.153 ± 1.528
1.298AspCys: 1.298 ± 0.572
2.076AspAsp: 2.076 ± 0.817
1.817AspGlu: 1.817 ± 1.137
1.817AspPhe: 1.817 ± 0.165
1.817AspGly: 1.817 ± 0.477
2.336AspHis: 2.336 ± 0.751
1.038AspIle: 1.038 ± 0.403
2.076AspLys: 2.076 ± 0.466
7.267AspLeu: 7.267 ± 0.749
0.779AspMet: 0.779 ± 0.28
1.817AspAsn: 1.817 ± 0.822
4.672AspPro: 4.672 ± 1.238
2.076AspGln: 2.076 ± 0.806
2.076AspArg: 2.076 ± 0.474
2.595AspSer: 2.595 ± 1.156
2.855AspThr: 2.855 ± 0.254
2.595AspVal: 2.595 ± 0.557
1.817AspTrp: 1.817 ± 0.617
1.298AspTyr: 1.298 ± 0.48
0.0AspXaa: 0.0 ± 0.0
Glu
6.488GluAla: 6.488 ± 1.397
1.038GluCys: 1.038 ± 1.161
3.893GluAsp: 3.893 ± 1.153
5.191GluGlu: 5.191 ± 1.33
1.817GluPhe: 1.817 ± 0.751
4.412GluGly: 4.412 ± 0.522
1.298GluHis: 1.298 ± 0.373
3.634GluIle: 3.634 ± 1.018
2.595GluLys: 2.595 ± 1.086
5.71GluLeu: 5.71 ± 0.982
1.817GluMet: 1.817 ± 1.012
1.038GluAsn: 1.038 ± 0.403
2.076GluPro: 2.076 ± 0.701
2.076GluGln: 2.076 ± 0.594
3.893GluArg: 3.893 ± 0.447
4.672GluSer: 4.672 ± 1.435
3.634GluThr: 3.634 ± 0.746
3.374GluVal: 3.374 ± 0.218
1.298GluTrp: 1.298 ± 0.45
0.519GluTyr: 0.519 ± 0.276
0.0GluXaa: 0.0 ± 0.0
Phe
1.557PheAla: 1.557 ± 0.568
0.519PheCys: 0.519 ± 0.466
0.779PheAsp: 0.779 ± 0.414
1.557PheGlu: 1.557 ± 0.386
1.817PhePhe: 1.817 ± 0.398
1.557PheGly: 1.557 ± 0.657
1.557PheHis: 1.557 ± 0.559
0.779PheIle: 0.779 ± 0.521
0.0PheLys: 0.0 ± 0.0
2.076PheLeu: 2.076 ± 0.557
1.038PheMet: 1.038 ± 0.433
1.817PheAsn: 1.817 ± 0.479
3.374PhePro: 3.374 ± 0.746
1.038PheGln: 1.038 ± 0.349
2.595PheArg: 2.595 ± 0.731
2.855PheSer: 2.855 ± 0.645
1.298PheThr: 1.298 ± 0.513
2.076PheVal: 2.076 ± 0.557
0.26PheTrp: 0.26 ± 0.297
1.298PheTyr: 1.298 ± 0.51
0.0PheXaa: 0.0 ± 0.0
Gly
4.672GlyAla: 4.672 ± 1.303
0.779GlyCys: 0.779 ± 0.28
2.595GlyAsp: 2.595 ± 0.731
4.153GlyGlu: 4.153 ± 0.992
2.855GlyPhe: 2.855 ± 0.737
3.114GlyGly: 3.114 ± 0.624
1.298GlyHis: 1.298 ± 0.575
2.855GlyIle: 2.855 ± 0.962
2.076GlyLys: 2.076 ± 0.918
7.008GlyLeu: 7.008 ± 2.099
1.557GlyMet: 1.557 ± 0.909
1.557GlyAsn: 1.557 ± 0.517
2.595GlyPro: 2.595 ± 1.026
2.855GlyGln: 2.855 ± 0.746
2.595GlyArg: 2.595 ± 0.287
6.229GlySer: 6.229 ± 0.46
3.374GlyThr: 3.374 ± 0.884
4.153GlyVal: 4.153 ± 1.188
1.298GlyTrp: 1.298 ± 0.824
1.038GlyTyr: 1.038 ± 0.565
0.0GlyXaa: 0.0 ± 0.0
His
2.336HisAla: 2.336 ± 0.794
0.519HisCys: 0.519 ± 0.466
1.557HisAsp: 1.557 ± 0.375
1.557HisGlu: 1.557 ± 0.823
0.519HisPhe: 0.519 ± 0.276
1.817HisGly: 1.817 ± 0.692
1.038HisHis: 1.038 ± 0.54
1.038HisIle: 1.038 ± 0.516
1.298HisLys: 1.298 ± 0.884
4.412HisLeu: 4.412 ± 1.173
0.26HisMet: 0.26 ± 0.138
0.26HisAsn: 0.26 ± 0.138
2.336HisPro: 2.336 ± 1.023
1.817HisGln: 1.817 ± 0.947
3.893HisArg: 3.893 ± 1.069
2.336HisSer: 2.336 ± 0.725
1.557HisThr: 1.557 ± 0.568
1.557HisVal: 1.557 ± 0.536
1.038HisTrp: 1.038 ± 0.432
0.26HisTyr: 0.26 ± 0.138
0.0HisXaa: 0.0 ± 0.0
Ile
3.374IleAla: 3.374 ± 0.951
0.779IleCys: 0.779 ± 0.316
1.298IleAsp: 1.298 ± 0.513
3.634IleGlu: 3.634 ± 0.859
1.817IlePhe: 1.817 ± 0.165
2.595IleGly: 2.595 ± 1.021
2.595IleHis: 2.595 ± 0.731
1.557IleIle: 1.557 ± 0.823
2.855IleLys: 2.855 ± 0.181
3.374IleLeu: 3.374 ± 0.55
1.038IleMet: 1.038 ± 0.932
0.519IleAsn: 0.519 ± 0.65
2.336IlePro: 2.336 ± 0.594
2.855IleGln: 2.855 ± 1.083
2.595IleArg: 2.595 ± 0.751
3.634IleSer: 3.634 ± 1.03
2.595IleThr: 2.595 ± 0.751
1.038IleVal: 1.038 ± 0.349
1.038IleTrp: 1.038 ± 0.408
1.557IleTyr: 1.557 ± 0.827
0.0IleXaa: 0.0 ± 0.0
Lys
3.634LysAla: 3.634 ± 1.413
0.0LysCys: 0.0 ± 0.0
2.076LysAsp: 2.076 ± 1.285
4.412LysGlu: 4.412 ± 0.997
1.817LysPhe: 1.817 ± 0.796
3.634LysGly: 3.634 ± 0.682
0.0LysHis: 0.0 ± 0.0
2.336LysIle: 2.336 ± 0.725
3.374LysLys: 3.374 ± 2.241
5.71LysLeu: 5.71 ± 0.852
2.336LysMet: 2.336 ± 0.63
1.038LysAsn: 1.038 ± 0.403
2.076LysPro: 2.076 ± 1.487
1.817LysGln: 1.817 ± 1.137
1.557LysArg: 1.557 ± 0.262
2.855LysSer: 2.855 ± 1.377
1.298LysThr: 1.298 ± 0.48
2.076LysVal: 2.076 ± 1.167
0.519LysTrp: 0.519 ± 0.274
0.26LysTyr: 0.26 ± 0.325
0.0LysXaa: 0.0 ± 0.0
Leu
10.122LeuAla: 10.122 ± 0.882
1.817LeuCys: 1.817 ± 0.458
6.748LeuAsp: 6.748 ± 0.949
6.488LeuGlu: 6.488 ± 1.602
1.817LeuPhe: 1.817 ± 0.617
6.748LeuGly: 6.748 ± 1.437
5.71LeuHis: 5.71 ± 0.852
5.45LeuIle: 5.45 ± 0.997
4.153LeuLys: 4.153 ± 2.902
14.275LeuLeu: 14.275 ± 3.004
3.114LeuMet: 3.114 ± 1.051
3.374LeuAsn: 3.374 ± 0.469
6.748LeuPro: 6.748 ± 0.835
5.191LeuGln: 5.191 ± 1.911
8.046LeuArg: 8.046 ± 1.543
8.046LeuSer: 8.046 ± 4.218
6.229LeuThr: 6.229 ± 1.048
7.267LeuVal: 7.267 ± 1.691
0.779LeuTrp: 0.779 ± 0.414
2.076LeuTyr: 2.076 ± 0.831
0.0LeuXaa: 0.0 ± 0.0
Met
2.336MetAla: 2.336 ± 0.248
1.557MetCys: 1.557 ± 0.517
1.038MetAsp: 1.038 ± 1.024
0.779MetGlu: 0.779 ± 0.28
1.557MetPhe: 1.557 ± 0.386
1.038MetGly: 1.038 ± 0.551
0.26MetHis: 0.26 ± 0.325
0.779MetIle: 0.779 ± 0.414
2.076MetLys: 2.076 ± 1.128
1.557MetLeu: 1.557 ± 1.339
0.519MetMet: 0.519 ± 0.65
0.26MetAsn: 0.26 ± 0.297
0.779MetPro: 0.779 ± 0.414
0.779MetGln: 0.779 ± 0.414
1.038MetArg: 1.038 ± 0.551
2.336MetSer: 2.336 ± 1.062
1.817MetThr: 1.817 ± 0.789
1.298MetVal: 1.298 ± 0.51
0.519MetTrp: 0.519 ± 0.274
1.298MetTyr: 1.298 ± 0.373
0.0MetXaa: 0.0 ± 0.0
Asn
2.076AsnAla: 2.076 ± 1.427
0.0AsnCys: 0.0 ± 0.0
1.038AsnAsp: 1.038 ± 0.403
1.038AsnGlu: 1.038 ± 0.349
0.26AsnPhe: 0.26 ± 0.138
0.779AsnGly: 0.779 ± 0.555
0.519AsnHis: 0.519 ± 0.276
1.817AsnIle: 1.817 ± 0.479
1.557AsnLys: 1.557 ± 0.557
4.153AsnLeu: 4.153 ± 0.604
0.0AsnMet: 0.0 ± 0.0
0.26AsnAsn: 0.26 ± 0.325
1.038AsnPro: 1.038 ± 0.349
1.298AsnGln: 1.298 ± 0.45
1.038AsnArg: 1.038 ± 0.54
2.595AsnSer: 2.595 ± 1.248
1.298AsnThr: 1.298 ± 0.385
0.779AsnVal: 0.779 ± 0.414
0.26AsnTrp: 0.26 ± 0.297
1.298AsnTyr: 1.298 ± 0.662
0.0AsnXaa: 0.0 ± 0.0
Pro
6.748ProAla: 6.748 ± 1.548
0.779ProCys: 0.779 ± 0.328
3.374ProAsp: 3.374 ± 0.469
4.153ProGlu: 4.153 ± 0.929
1.038ProPhe: 1.038 ± 0.403
3.374ProGly: 3.374 ± 0.985
2.855ProHis: 2.855 ± 0.854
1.557ProIle: 1.557 ± 0.657
0.26ProLys: 0.26 ± 0.537
4.672ProLeu: 4.672 ± 0.868
0.779ProMet: 0.779 ± 0.521
1.298ProAsn: 1.298 ± 0.689
6.748ProPro: 6.748 ± 2.228
1.298ProGln: 1.298 ± 0.373
4.931ProArg: 4.931 ± 0.912
7.008ProSer: 7.008 ± 2.35
2.076ProThr: 2.076 ± 0.891
3.893ProVal: 3.893 ± 0.812
1.557ProTrp: 1.557 ± 0.262
1.038ProTyr: 1.038 ± 0.403
0.0ProXaa: 0.0 ± 0.0
Gln
3.374GlnAla: 3.374 ± 0.82
0.26GlnCys: 0.26 ± 0.138
2.336GlnAsp: 2.336 ± 0.582
2.595GlnGlu: 2.595 ± 0.745
1.298GlnPhe: 1.298 ± 0.532
2.336GlnGly: 2.336 ± 0.582
1.817GlnHis: 1.817 ± 0.419
2.595GlnIle: 2.595 ± 0.633
3.374GlnLys: 3.374 ± 0.796
4.672GlnLeu: 4.672 ± 0.851
0.779GlnMet: 0.779 ± 0.582
0.519GlnAsn: 0.519 ± 0.274
1.298GlnPro: 1.298 ± 0.513
3.114GlnGln: 3.114 ± 0.911
3.374GlnArg: 3.374 ± 0.848
4.153GlnSer: 4.153 ± 1.004
3.114GlnThr: 3.114 ± 0.725
2.595GlnVal: 2.595 ± 0.631
0.519GlnTrp: 0.519 ± 0.276
0.519GlnTyr: 0.519 ± 0.27
0.0GlnXaa: 0.0 ± 0.0
Arg
9.343ArgAla: 9.343 ± 1.594
0.779ArgCys: 0.779 ± 0.414
2.855ArgAsp: 2.855 ± 0.962
3.114ArgGlu: 3.114 ± 0.145
2.595ArgPhe: 2.595 ± 1.026
2.855ArgGly: 2.855 ± 0.771
2.336ArgHis: 2.336 ± 0.482
3.374ArgIle: 3.374 ± 1.838
1.557ArgLys: 1.557 ± 0.549
8.046ArgLeu: 8.046 ± 1.206
1.038ArgMet: 1.038 ± 0.428
1.298ArgAsn: 1.298 ± 0.737
3.634ArgPro: 3.634 ± 1.264
2.076ArgGln: 2.076 ± 0.515
4.153ArgArg: 4.153 ± 1.089
5.191ArgSer: 5.191 ± 1.579
4.412ArgThr: 4.412 ± 1.198
4.931ArgVal: 4.931 ± 1.418
1.557ArgTrp: 1.557 ± 0.559
1.298ArgTyr: 1.298 ± 0.48
0.0ArgXaa: 0.0 ± 0.0
Ser
9.603SerAla: 9.603 ± 2.901
1.557SerCys: 1.557 ± 0.634
3.114SerAsp: 3.114 ± 1.279
4.931SerGlu: 4.931 ± 1.061
2.076SerPhe: 2.076 ± 0.153
5.969SerGly: 5.969 ± 1.609
1.038SerHis: 1.038 ± 0.652
3.634SerIle: 3.634 ± 0.694
2.076SerLys: 2.076 ± 1.128
9.084SerLeu: 9.084 ± 1.531
1.817SerMet: 1.817 ± 0.4
1.557SerAsn: 1.557 ± 0.568
5.191SerPro: 5.191 ± 1.968
3.893SerGln: 3.893 ± 0.977
5.191SerArg: 5.191 ± 1.263
7.008SerSer: 7.008 ± 2.505
7.008SerThr: 7.008 ± 1.798
4.672SerVal: 4.672 ± 0.961
1.038SerTrp: 1.038 ± 0.403
2.855SerTyr: 2.855 ± 0.181
0.0SerXaa: 0.0 ± 0.0
Thr
5.71ThrAla: 5.71 ± 1.01
0.0ThrCys: 0.0 ± 0.0
3.114ThrAsp: 3.114 ± 0.967
1.817ThrGlu: 1.817 ± 0.947
2.855ThrPhe: 2.855 ± 0.505
4.153ThrGly: 4.153 ± 1.017
1.038ThrHis: 1.038 ± 0.791
2.336ThrIle: 2.336 ± 0.959
2.076ThrLys: 2.076 ± 0.807
5.71ThrLeu: 5.71 ± 1.554
2.076ThrMet: 2.076 ± 0.544
0.779ThrAsn: 0.779 ± 0.685
3.634ThrPro: 3.634 ± 1.513
3.114ThrGln: 3.114 ± 1.004
5.191ThrArg: 5.191 ± 1.341
4.672ThrSer: 4.672 ± 2.239
3.634ThrThr: 3.634 ± 1.392
4.412ThrVal: 4.412 ± 0.681
1.557ThrTrp: 1.557 ± 0.827
0.779ThrTyr: 0.779 ± 0.521
0.0ThrXaa: 0.0 ± 0.0
Val
4.672ValAla: 4.672 ± 0.825
1.038ValCys: 1.038 ± 0.284
2.336ValAsp: 2.336 ± 0.574
2.595ValGlu: 2.595 ± 0.287
1.817ValPhe: 1.817 ± 0.797
2.855ValGly: 2.855 ± 0.668
0.519ValHis: 0.519 ± 0.27
4.153ValIle: 4.153 ± 1.167
4.153ValLys: 4.153 ± 1.089
8.565ValLeu: 8.565 ± 1.071
1.298ValMet: 1.298 ± 0.373
1.298ValAsn: 1.298 ± 0.303
2.855ValPro: 2.855 ± 1.145
3.374ValGln: 3.374 ± 0.382
4.412ValArg: 4.412 ± 1.304
2.595ValSer: 2.595 ± 0.771
4.672ValThr: 4.672 ± 1.377
2.076ValVal: 2.076 ± 0.342
1.038ValTrp: 1.038 ± 0.433
2.076ValTyr: 2.076 ± 0.557
0.0ValXaa: 0.0 ± 0.0
Trp
2.336TrpAla: 2.336 ± 0.792
0.779TrpCys: 0.779 ± 0.316
1.298TrpAsp: 1.298 ± 0.303
1.817TrpGlu: 1.817 ± 0.165
0.0TrpPhe: 0.0 ± 0.0
0.26TrpGly: 0.26 ± 0.297
0.519TrpHis: 0.519 ± 0.276
0.26TrpIle: 0.26 ± 0.138
1.038TrpLys: 1.038 ± 0.516
1.298TrpLeu: 1.298 ± 0.513
0.26TrpMet: 0.26 ± 0.138
0.779TrpAsn: 0.779 ± 0.428
0.519TrpPro: 0.519 ± 0.276
0.26TrpGln: 0.26 ± 0.138
1.817TrpArg: 1.817 ± 0.711
0.779TrpSer: 0.779 ± 0.428
1.298TrpThr: 1.298 ± 0.303
1.817TrpVal: 1.817 ± 0.965
0.519TrpTrp: 0.519 ± 0.595
0.779TrpTyr: 0.779 ± 0.428
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.557TyrAla: 1.557 ± 0.262
0.519TyrCys: 0.519 ± 0.58
2.076TyrAsp: 2.076 ± 0.74
1.038TyrGlu: 1.038 ± 0.408
0.519TyrPhe: 0.519 ± 0.276
1.557TyrGly: 1.557 ± 0.375
1.817TyrHis: 1.817 ± 0.692
0.26TyrIle: 0.26 ± 0.138
0.779TyrLys: 0.779 ± 1.078
3.114TyrLeu: 3.114 ± 1.063
0.0TyrMet: 0.0 ± 0.0
0.519TyrAsn: 0.519 ± 0.276
1.557TyrPro: 1.557 ± 0.557
1.038TyrGln: 1.038 ± 0.54
1.557TyrArg: 1.557 ± 0.375
2.076TyrSer: 2.076 ± 0.319
2.076TyrThr: 2.076 ± 0.569
1.038TyrVal: 1.038 ± 0.54
0.26TyrTrp: 0.26 ± 0.138
0.519TyrTyr: 0.519 ± 0.276
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3854 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski