Amino acid dipepetide frequency for Halobellus clavatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.082AlaAla: 14.082 ± 0.183	0.656AlaCys: 0.656 ± 0.026	9.655AlaAsp: 9.655 ± 0.136	8.481AlaGlu: 8.481 ± 0.101	3.875AlaPhe: 3.875 ± 0.075	9.53AlaGly: 9.53 ± 0.123	1.875AlaHis: 1.875 ± 0.05	4.857AlaIle: 4.857 ± 0.078	1.821AlaLys: 1.821 ± 0.047	9.944AlaLeu: 9.944 ± 0.137	1.872AlaMet: 1.872 ± 0.044	2.398AlaAsn: 2.398 ± 0.044	4.113AlaPro: 4.113 ± 0.061	2.424AlaGln: 2.424 ± 0.049	6.031AlaArg: 6.031 ± 0.083	5.893AlaSer: 5.893 ± 0.101	7.112AlaThr: 7.112 ± 0.107	10.406AlaVal: 10.406 ± 0.133	1.16AlaTrp: 1.16 ± 0.038	2.716AlaTyr: 2.716 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.548CysAla: 0.548 ± 0.025	0.073CysCys: 0.073 ± 0.01	0.529CysAsp: 0.529 ± 0.021	0.544CysGlu: 0.544 ± 0.025	0.159CysPhe: 0.159 ± 0.012	0.819CysGly: 0.819 ± 0.037	0.164CysHis: 0.164 ± 0.013	0.229CysIle: 0.229 ± 0.014	0.108CysLys: 0.108 ± 0.009	0.51CysLeu: 0.51 ± 0.022	0.09CysMet: 0.09 ± 0.009	0.145CysAsn: 0.145 ± 0.012	0.518CysPro: 0.518 ± 0.023	0.164CysGln: 0.164 ± 0.012	0.479CysArg: 0.479 ± 0.02	0.401CysSer: 0.401 ± 0.022	0.37CysThr: 0.37 ± 0.02	0.458CysVal: 0.458 ± 0.021	0.077CysTrp: 0.077 ± 0.008	0.174CysTyr: 0.174 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	10.392AspAla: 10.392 ± 0.134	0.519AspCys: 0.519 ± 0.024	7.802AspAsp: 7.802 ± 0.117	7.628AspGlu: 7.628 ± 0.119	2.122AspPhe: 2.122 ± 0.047	7.904AspGly: 7.904 ± 0.118	1.711AspHis: 1.711 ± 0.047	3.163AspIle: 3.163 ± 0.058	0.978AspLys: 0.978 ± 0.034	7.162AspLeu: 7.162 ± 0.096	1.033AspMet: 1.033 ± 0.029	1.3AspAsn: 1.3 ± 0.04	4.885AspPro: 4.885 ± 0.073	1.838AspGln: 1.838 ± 0.044	6.395AspArg: 6.395 ± 0.095	4.012AspSer: 4.012 ± 0.069	4.26AspThr: 4.26 ± 0.086	7.863AspVal: 7.863 ± 0.093	0.913AspTrp: 0.913 ± 0.036	1.79AspTyr: 1.79 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	8.733GluAla: 8.733 ± 0.11	0.506GluCys: 0.506 ± 0.024	5.544GluAsp: 5.544 ± 0.104	6.483GluGlu: 6.483 ± 0.123	2.749GluPhe: 2.749 ± 0.061	5.01GluGly: 5.01 ± 0.079	1.904GluHis: 1.904 ± 0.043	4.034GluIle: 4.034 ± 0.079	1.799GluLys: 1.799 ± 0.055	7.493GluLeu: 7.493 ± 0.106	1.936GluMet: 1.936 ± 0.043	2.277GluAsn: 2.277 ± 0.06	3.642GluPro: 3.642 ± 0.065	2.876GluGln: 2.876 ± 0.066	7.288GluArg: 7.288 ± 0.114	5.664GluSer: 5.664 ± 0.092	6.555GluThr: 6.555 ± 0.087	5.496GluVal: 5.496 ± 0.078	1.112GluTrp: 1.112 ± 0.035	2.767GluTyr: 2.767 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	3.604PheAla: 3.604 ± 0.068	0.243PheCys: 0.243 ± 0.016	3.069PheAsp: 3.069 ± 0.055	3.299PheGlu: 3.299 ± 0.064	1.048PhePhe: 1.048 ± 0.038	3.192PheGly: 3.192 ± 0.063	0.616PheHis: 0.616 ± 0.024	1.076PheIle: 1.076 ± 0.037	0.512PheLys: 0.512 ± 0.021	2.837PheLeu: 2.837 ± 0.053	0.405PheMet: 0.405 ± 0.02	0.712PheAsn: 0.712 ± 0.027	1.349PhePro: 1.349 ± 0.037	0.875PheGln: 0.875 ± 0.034	1.848PheArg: 1.848 ± 0.04	1.725PheSer: 1.725 ± 0.044	1.94PheThr: 1.94 ± 0.052	3.226PheVal: 3.226 ± 0.062	0.408PheTrp: 0.408 ± 0.021	0.878PheTyr: 0.878 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	8.154GlyAla: 8.154 ± 0.124	0.655GlyCys: 0.655 ± 0.028	6.542GlyAsp: 6.542 ± 0.102	6.664GlyGlu: 6.664 ± 0.097	3.113GlyPhe: 3.113 ± 0.063	7.384GlyGly: 7.384 ± 0.122	1.574GlyHis: 1.574 ± 0.042	4.277GlyIle: 4.277 ± 0.074	1.726GlyLys: 1.726 ± 0.041	7.268GlyLeu: 7.268 ± 0.107	1.576GlyMet: 1.576 ± 0.042	1.923GlyAsn: 1.923 ± 0.053	3.455GlyPro: 3.455 ± 0.067	2.077GlyGln: 2.077 ± 0.048	4.956GlyArg: 4.956 ± 0.081	5.442GlySer: 5.442 ± 0.08	5.761GlyThr: 5.761 ± 0.11	7.397GlyVal: 7.397 ± 0.102	1.056GlyTrp: 1.056 ± 0.031	2.595GlyTyr: 2.595 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	1.881HisAla: 1.881 ± 0.049	0.18HisCys: 0.18 ± 0.014	1.735HisAsp: 1.735 ± 0.045	1.656HisGlu: 1.656 ± 0.048	0.548HisPhe: 0.548 ± 0.023	1.767HisGly: 1.767 ± 0.051	0.497HisHis: 0.497 ± 0.019	0.763HisIle: 0.763 ± 0.025	0.302HisLys: 0.302 ± 0.019	1.782HisLeu: 1.782 ± 0.045	0.229HisMet: 0.229 ± 0.013	0.492HisAsn: 0.492 ± 0.021	1.27HisPro: 1.27 ± 0.037	0.486HisGln: 0.486 ± 0.024	1.406HisArg: 1.406 ± 0.042	0.922HisSer: 0.922 ± 0.033	1.042HisThr: 1.042 ± 0.029	1.769HisVal: 1.769 ± 0.051	0.234HisTrp: 0.234 ± 0.016	0.569HisTyr: 0.569 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	4.645IleAla: 4.645 ± 0.073	0.256IleCys: 0.256 ± 0.015	4.198IleAsp: 4.198 ± 0.065	4.532IleGlu: 4.532 ± 0.077	1.089IlePhe: 1.089 ± 0.03	3.903IleGly: 3.903 ± 0.063	0.87IleHis: 0.87 ± 0.031	1.449IleIle: 1.449 ± 0.044	0.772IleLys: 0.772 ± 0.03	3.15IleLeu: 3.15 ± 0.059	0.422IleMet: 0.422 ± 0.023	1.035IleAsn: 1.035 ± 0.031	2.13IlePro: 2.13 ± 0.047	1.274IleGln: 1.274 ± 0.038	2.869IleArg: 2.869 ± 0.052	2.335IleSer: 2.335 ± 0.051	2.521IleThr: 2.521 ± 0.062	3.827IleVal: 3.827 ± 0.067	0.325IleTrp: 0.325 ± 0.02	0.954IleTyr: 0.954 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	1.671LysAla: 1.671 ± 0.044	0.124LysCys: 0.124 ± 0.01	1.019LysAsp: 1.019 ± 0.036	1.362LysGlu: 1.362 ± 0.044	0.577LysPhe: 0.577 ± 0.024	1.244LysGly: 1.244 ± 0.039	0.463LysHis: 0.463 ± 0.022	0.873LysIle: 0.873 ± 0.033	0.558LysLys: 0.558 ± 0.028	1.584LysLeu: 1.584 ± 0.044	0.374LysMet: 0.374 ± 0.02	0.632LysAsn: 0.632 ± 0.029	0.87LysPro: 0.87 ± 0.03	0.83LysGln: 0.83 ± 0.034	1.641LysArg: 1.641 ± 0.041	1.226LysSer: 1.226 ± 0.04	1.378LysThr: 1.378 ± 0.038	1.155LysVal: 1.155 ± 0.041	0.253LysTrp: 0.253 ± 0.015	0.619LysTyr: 0.619 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	10.26LeuAla: 10.26 ± 0.143	0.519LeuCys: 0.519 ± 0.022	7.553LeuAsp: 7.553 ± 0.095	6.608LeuGlu: 6.608 ± 0.115	3.125LeuPhe: 3.125 ± 0.07	7.615LeuGly: 7.615 ± 0.11	1.534LeuHis: 1.534 ± 0.042	3.064LeuIle: 3.064 ± 0.065	1.69LeuLys: 1.69 ± 0.051	8.58LeuLeu: 8.58 ± 0.136	1.134LeuMet: 1.134 ± 0.035	2.041LeuAsn: 2.041 ± 0.052	4.213LeuPro: 4.213 ± 0.071	2.296LeuGln: 2.296 ± 0.048	5.795LeuArg: 5.795 ± 0.077	6.089LeuSer: 6.089 ± 0.075	5.526LeuThr: 5.526 ± 0.081	7.954LeuVal: 7.954 ± 0.115	0.913LeuTrp: 0.913 ± 0.031	2.221LeuTyr: 2.221 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	1.598MetAla: 1.598 ± 0.041	0.129MetCys: 0.129 ± 0.011	1.109MetAsp: 1.109 ± 0.033	1.044MetGlu: 1.044 ± 0.035	0.444MetPhe: 0.444 ± 0.025	1.226MetGly: 1.226 ± 0.035	0.307MetHis: 0.307 ± 0.016	0.672MetIle: 0.672 ± 0.025	0.442MetLys: 0.442 ± 0.021	1.384MetLeu: 1.384 ± 0.037	0.281MetMet: 0.281 ± 0.018	0.597MetAsn: 0.597 ± 0.025	0.797MetPro: 0.797 ± 0.025	0.48MetGln: 0.48 ± 0.023	1.08MetArg: 1.08 ± 0.032	1.509MetSer: 1.509 ± 0.037	1.426MetThr: 1.426 ± 0.035	1.061MetVal: 1.061 ± 0.033	0.154MetTrp: 0.154 ± 0.013	0.375MetTyr: 0.375 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.635AsnAla: 2.635 ± 0.061	0.22AsnCys: 0.22 ± 0.015	1.76AsnAsp: 1.76 ± 0.055	1.848AsnGlu: 1.848 ± 0.054	0.72AsnPhe: 0.72 ± 0.03	2.038AsnGly: 2.038 ± 0.067	0.469AsnHis: 0.469 ± 0.023	1.0AsnIle: 1.0 ± 0.034	0.484AsnLys: 0.484 ± 0.025	2.035AsnLeu: 2.035 ± 0.051	0.394AsnMet: 0.394 ± 0.021	0.622AsnAsn: 0.622 ± 0.029	1.585AsnPro: 1.585 ± 0.04	0.691AsnGln: 0.691 ± 0.027	1.736AsnArg: 1.736 ± 0.048	1.187AsnSer: 1.187 ± 0.038	1.432AsnThr: 1.432 ± 0.047	2.247AsnVal: 2.247 ± 0.062	0.329AsnTrp: 0.329 ± 0.019	0.69AsnTyr: 0.69 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.836ProAla: 4.836 ± 0.068	0.226ProCys: 0.226 ± 0.013	4.914ProAsp: 4.914 ± 0.076	4.762ProGlu: 4.762 ± 0.071	1.544ProPhe: 1.544 ± 0.039	3.787ProGly: 3.787 ± 0.069	0.895ProHis: 0.895 ± 0.029	2.061ProIle: 2.061 ± 0.043	0.844ProLys: 0.844 ± 0.029	3.676ProLeu: 3.676 ± 0.066	0.785ProMet: 0.785 ± 0.03	1.167ProAsn: 1.167 ± 0.032	2.253ProPro: 2.253 ± 0.048	1.122ProGln: 1.122 ± 0.034	2.294ProArg: 2.294 ± 0.048	2.884ProSer: 2.884 ± 0.049	3.424ProThr: 3.424 ± 0.061	3.973ProVal: 3.973 ± 0.065	0.491ProTrp: 0.491 ± 0.022	1.146ProTyr: 1.146 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.567GlnAla: 2.567 ± 0.054	0.185GlnCys: 0.185 ± 0.014	1.501GlnAsp: 1.501 ± 0.042	1.864GlnGlu: 1.864 ± 0.046	1.165GlnPhe: 1.165 ± 0.032	1.667GlnGly: 1.667 ± 0.048	0.597GlnHis: 0.597 ± 0.023	1.353GlnIle: 1.353 ± 0.037	0.654GlnLys: 0.654 ± 0.028	2.486GlnLeu: 2.486 ± 0.055	0.588GlnMet: 0.588 ± 0.024	0.845GlnAsn: 0.845 ± 0.032	1.133GlnPro: 1.133 ± 0.032	1.068GlnGln: 1.068 ± 0.033	2.139GlnArg: 2.139 ± 0.048	1.914GlnSer: 1.914 ± 0.041	2.064GlnThr: 2.064 ± 0.052	1.833GlnVal: 1.833 ± 0.04	0.357GlnTrp: 0.357 ± 0.019	0.991GlnTyr: 0.991 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	6.461ArgAla: 6.461 ± 0.096	0.449ArgCys: 0.449 ± 0.021	5.245ArgAsp: 5.245 ± 0.079	6.402ArgGlu: 6.402 ± 0.099	2.293ArgPhe: 2.293 ± 0.05	4.553ArgGly: 4.553 ± 0.072	1.258ArgHis: 1.258 ± 0.038	3.273ArgIle: 3.273 ± 0.056	1.341ArgLys: 1.341 ± 0.041	6.239ArgLeu: 6.239 ± 0.075	1.212ArgMet: 1.212 ± 0.033	1.753ArgAsn: 1.753 ± 0.046	2.682ArgPro: 2.682 ± 0.061	2.017ArgGln: 2.017 ± 0.053	5.132ArgArg: 5.132 ± 0.077	3.97ArgSer: 3.97 ± 0.064	4.075ArgThr: 4.075 ± 0.069	5.277ArgVal: 5.277 ± 0.08	0.789ArgTrp: 0.789 ± 0.031	1.921ArgTyr: 1.921 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	5.904SerAla: 5.904 ± 0.08	0.299SerCys: 0.299 ± 0.02	4.855SerAsp: 4.855 ± 0.077	4.778SerGlu: 4.778 ± 0.084	1.999SerPhe: 1.999 ± 0.04	5.617SerGly: 5.617 ± 0.093	1.111SerHis: 1.111 ± 0.037	2.767SerIle: 2.767 ± 0.056	1.208SerLys: 1.208 ± 0.033	5.422SerLeu: 5.422 ± 0.077	1.08SerMet: 1.08 ± 0.029	1.486SerAsn: 1.486 ± 0.04	2.846SerPro: 2.846 ± 0.05	1.6SerGln: 1.6 ± 0.042	3.415SerArg: 3.415 ± 0.068	3.339SerSer: 3.339 ± 0.083	3.952SerThr: 3.952 ± 0.07	5.22SerVal: 5.22 ± 0.081	0.622SerTrp: 0.622 ± 0.024	1.418SerTyr: 1.418 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	7.358ThrAla: 7.358 ± 0.115	0.356ThrCys: 0.356 ± 0.019	5.742ThrAsp: 5.742 ± 0.072	4.942ThrGlu: 4.942 ± 0.069	2.117ThrPhe: 2.117 ± 0.056	5.771ThrGly: 5.771 ± 0.08	1.286ThrHis: 1.286 ± 0.038	2.97ThrIle: 2.97 ± 0.069	1.098ThrLys: 1.098 ± 0.038	5.714ThrLeu: 5.714 ± 0.086	0.94ThrMet: 0.94 ± 0.028	1.622ThrAsn: 1.622 ± 0.058	3.43ThrPro: 3.43 ± 0.056	1.604ThrGln: 1.604 ± 0.043	3.471ThrArg: 3.471 ± 0.058	3.233ThrSer: 3.233 ± 0.061	4.345ThrThr: 4.345 ± 0.101	6.941ThrVal: 6.941 ± 0.161	0.688ThrTrp: 0.688 ± 0.025	1.854ThrTyr: 1.854 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	9.95ValAla: 9.95 ± 0.148	0.622ValCys: 0.622 ± 0.028	7.544ValAsp: 7.544 ± 0.094	7.733ValGlu: 7.733 ± 0.09	2.894ValPhe: 2.894 ± 0.055	7.538ValGly: 7.538 ± 0.129	1.533ValHis: 1.533 ± 0.043	3.256ValIle: 3.256 ± 0.055	1.396ValLys: 1.396 ± 0.037	7.699ValLeu: 7.699 ± 0.104	1.215ValMet: 1.215 ± 0.036	2.003ValAsn: 2.003 ± 0.062	4.17ValPro: 4.17 ± 0.064	2.0ValGln: 2.0 ± 0.049	5.482ValArg: 5.482 ± 0.082	5.306ValSer: 5.306 ± 0.092	6.041ValThr: 6.041 ± 0.113	8.857ValVal: 8.857 ± 0.133	0.781ValTrp: 0.781 ± 0.025	2.037ValTyr: 2.037 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.932TrpAla: 0.932 ± 0.029	0.106TrpCys: 0.106 ± 0.011	0.79TrpAsp: 0.79 ± 0.027	0.815TrpGlu: 0.815 ± 0.031	0.425TrpPhe: 0.425 ± 0.02	0.807TrpGly: 0.807 ± 0.025	0.224TrpHis: 0.224 ± 0.014	0.548TrpIle: 0.548 ± 0.026	0.266TrpLys: 0.266 ± 0.015	1.147TrpLeu: 1.147 ± 0.039	0.218TrpMet: 0.218 ± 0.013	0.373TrpAsn: 0.373 ± 0.019	0.46TrpPro: 0.46 ± 0.019	0.411TrpGln: 0.411 ± 0.02	0.864TrpArg: 0.864 ± 0.029	0.653TrpSer: 0.653 ± 0.028	0.764TrpThr: 0.764 ± 0.027	0.819TrpVal: 0.819 ± 0.028	0.198TrpTrp: 0.198 ± 0.015	0.403TrpTyr: 0.403 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.69TyrAla: 2.69 ± 0.05	0.235TyrCys: 0.235 ± 0.015	2.563TyrAsp: 2.563 ± 0.053	2.422TyrGlu: 2.422 ± 0.059	0.857TyrPhe: 0.857 ± 0.029	2.226TyrGly: 2.226 ± 0.042	0.641TyrHis: 0.641 ± 0.025	0.87TyrIle: 0.87 ± 0.031	0.452TyrLys: 0.452 ± 0.024	2.621TyrLeu: 2.621 ± 0.051	0.331TyrMet: 0.331 ± 0.017	0.702TyrAsn: 0.702 ± 0.031	1.283TyrPro: 1.283 ± 0.031	0.84TyrGln: 0.84 ± 0.032	2.019TyrArg: 2.019 ± 0.048	1.234TyrSer: 1.234 ± 0.035	1.492TyrThr: 1.492 ± 0.041	2.277TyrVal: 2.277 ± 0.045	0.363TyrTrp: 0.363 ± 0.018	0.825TyrTyr: 0.825 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3679 proteins (1088495 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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