Amino acid dipepetide frequency for Xinzhou nematode virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.501AlaAla: 5.501 ± 2.41
0.846AlaCys: 0.846 ± 0.435
2.116AlaAsp: 2.116 ± 1.531
3.386AlaGlu: 3.386 ± 0.431
3.809AlaPhe: 3.809 ± 0.648
2.539AlaGly: 2.539 ± 2.623
2.962AlaHis: 2.962 ± 1.096
3.386AlaIle: 3.386 ± 0.431
2.962AlaLys: 2.962 ± 2.406
9.31AlaLeu: 9.31 ± 0.453
2.116AlaMet: 2.116 ± 0.222
2.539AlaAsn: 2.539 ± 1.305
4.232AlaPro: 4.232 ± 5.682
2.962AlaGln: 2.962 ± 1.096
5.925AlaArg: 5.925 ± 0.883
8.887AlaSer: 8.887 ± 0.67
2.116AlaThr: 2.116 ± 0.222
5.078AlaVal: 5.078 ± 2.628
0.0AlaTrp: 0.0 ± 0.0
2.116AlaTyr: 2.116 ± 0.222
0.0AlaXaa: 0.0 ± 0.0
Cys
1.693CysAla: 1.693 ± 0.87
0.0CysCys: 0.0 ± 0.0
0.423CysAsp: 0.423 ± 0.217
0.846CysGlu: 0.846 ± 0.435
0.846CysPhe: 0.846 ± 0.435
0.423CysGly: 0.423 ± 1.092
0.423CysHis: 0.423 ± 0.217
1.27CysIle: 1.27 ± 0.652
0.423CysLys: 0.423 ± 1.092
1.693CysLeu: 1.693 ± 0.439
0.846CysMet: 0.846 ± 0.435
0.423CysAsn: 0.423 ± 0.217
0.846CysPro: 0.846 ± 0.435
0.846CysGln: 0.846 ± 0.435
1.693CysArg: 1.693 ± 0.87
1.27CysSer: 1.27 ± 0.652
0.846CysThr: 0.846 ± 0.435
0.423CysVal: 0.423 ± 0.217
0.0CysTrp: 0.0 ± 0.0
0.846CysTyr: 0.846 ± 0.435
0.0CysXaa: 0.0 ± 0.0
Asp
2.116AspAla: 2.116 ± 1.531
0.423AspCys: 0.423 ± 1.092
1.693AspAsp: 1.693 ± 0.439
3.386AspGlu: 3.386 ± 3.498
1.27AspPhe: 1.27 ± 0.657
2.539AspGly: 2.539 ± 1.305
2.116AspHis: 2.116 ± 1.531
5.078AspIle: 5.078 ± 1.301
0.846AspLys: 0.846 ± 0.874
3.809AspLeu: 3.809 ± 0.648
0.423AspMet: 0.423 ± 0.217
2.116AspAsn: 2.116 ± 1.087
1.693AspPro: 1.693 ± 0.87
1.693AspGln: 1.693 ± 0.439
3.809AspArg: 3.809 ± 0.648
4.232AspSer: 4.232 ± 1.753
3.809AspThr: 3.809 ± 0.648
3.809AspVal: 3.809 ± 0.661
0.846AspTrp: 0.846 ± 0.874
1.693AspTyr: 1.693 ± 0.439
0.0AspXaa: 0.0 ± 0.0
Glu
4.655GluAla: 4.655 ± 1.536
2.116GluCys: 2.116 ± 0.222
2.116GluAsp: 2.116 ± 0.222
5.925GluGlu: 5.925 ± 2.193
2.962GluPhe: 2.962 ± 1.522
2.962GluGly: 2.962 ± 1.096
0.846GluHis: 0.846 ± 0.435
2.962GluIle: 2.962 ± 1.096
1.693GluLys: 1.693 ± 0.439
7.617GluLeu: 7.617 ± 1.323
0.423GluMet: 0.423 ± 0.217
0.423GluAsn: 0.423 ± 0.217
1.27GluPro: 1.27 ± 0.657
3.386GluGln: 3.386 ± 0.879
3.386GluArg: 3.386 ± 1.74
2.962GluSer: 2.962 ± 1.096
3.809GluThr: 3.809 ± 1.971
2.116GluVal: 2.116 ± 0.222
0.423GluTrp: 0.423 ± 0.217
0.423GluTyr: 0.423 ± 0.217
0.0GluXaa: 0.0 ± 0.0
Phe
2.539PheAla: 2.539 ± 0.004
0.423PheCys: 0.423 ± 0.217
1.27PheAsp: 1.27 ± 0.657
1.693PheGlu: 1.693 ± 0.439
0.846PhePhe: 0.846 ± 0.435
1.693PheGly: 1.693 ± 0.87
0.846PheHis: 0.846 ± 0.435
1.693PheIle: 1.693 ± 0.87
0.0PheLys: 0.0 ± 0.0
5.501PheLeu: 5.501 ± 2.827
0.846PheMet: 0.846 ± 0.435
0.846PheAsn: 0.846 ± 0.435
2.962PhePro: 2.962 ± 0.213
0.846PheGln: 0.846 ± 0.874
2.962PheArg: 2.962 ± 0.213
3.386PheSer: 3.386 ± 1.74
2.539PheThr: 2.539 ± 0.004
3.386PheVal: 3.386 ± 0.431
0.0PheTrp: 0.0 ± 0.0
0.846PheTyr: 0.846 ± 0.874
0.0PheXaa: 0.0 ± 0.0
Gly
2.539GlyAla: 2.539 ± 3.933
1.27GlyCys: 1.27 ± 0.652
2.962GlyAsp: 2.962 ± 2.406
2.962GlyGlu: 2.962 ± 1.522
3.386GlyPhe: 3.386 ± 0.879
2.116GlyGly: 2.116 ± 0.222
1.693GlyHis: 1.693 ± 0.87
4.232GlyIle: 4.232 ± 0.444
2.539GlyLys: 2.539 ± 1.305
5.078GlyLeu: 5.078 ± 1.318
0.0GlyMet: 0.0 ± 0.0
2.116GlyAsn: 2.116 ± 1.087
5.078GlyPro: 5.078 ± 1.301
1.27GlyGln: 1.27 ± 0.652
3.386GlyArg: 3.386 ± 0.431
3.386GlySer: 3.386 ± 2.188
3.386GlyThr: 3.386 ± 0.431
1.693GlyVal: 1.693 ± 0.439
0.846GlyTrp: 0.846 ± 0.435
1.693GlyTyr: 1.693 ± 0.439
0.0GlyXaa: 0.0 ± 0.0
His
3.386HisAla: 3.386 ± 1.74
0.423HisCys: 0.423 ± 0.217
0.423HisAsp: 0.423 ± 0.217
0.423HisGlu: 0.423 ± 0.217
0.846HisPhe: 0.846 ± 0.435
1.27HisGly: 1.27 ± 0.652
2.116HisHis: 2.116 ± 1.531
0.846HisIle: 0.846 ± 2.184
0.0HisLys: 0.0 ± 0.0
8.041HisLeu: 8.041 ± 1.514
0.846HisMet: 0.846 ± 0.435
1.27HisAsn: 1.27 ± 0.657
1.27HisPro: 1.27 ± 0.652
2.116HisGln: 2.116 ± 0.222
0.846HisArg: 0.846 ± 0.435
2.539HisSer: 2.539 ± 1.314
1.693HisThr: 1.693 ± 0.87
1.27HisVal: 1.27 ± 1.966
0.423HisTrp: 0.423 ± 0.217
0.423HisTyr: 0.423 ± 0.217
0.0HisXaa: 0.0 ± 0.0
Ile
5.078IleAla: 5.078 ± 0.009
0.423IleCys: 0.423 ± 0.217
2.116IleAsp: 2.116 ± 0.222
4.655IleGlu: 4.655 ± 1.536
2.116IlePhe: 2.116 ± 1.087
2.962IleGly: 2.962 ± 1.522
3.386IleHis: 3.386 ± 0.879
2.962IleIle: 2.962 ± 0.213
2.962IleLys: 2.962 ± 0.213
7.194IleLeu: 7.194 ± 2.388
2.116IleMet: 2.116 ± 1.429
0.846IleAsn: 0.846 ± 0.874
5.501IlePro: 5.501 ± 2.41
1.27IleGln: 1.27 ± 0.652
3.809IleArg: 3.809 ± 0.648
6.348IleSer: 6.348 ± 3.262
2.962IleThr: 2.962 ± 1.522
4.655IleVal: 4.655 ± 1.536
1.27IleTrp: 1.27 ± 0.652
1.27IleTyr: 1.27 ± 0.652
0.0IleXaa: 0.0 ± 0.0
Lys
3.386LysAla: 3.386 ± 2.188
0.423LysCys: 0.423 ± 0.217
0.423LysAsp: 0.423 ± 1.092
3.809LysGlu: 3.809 ± 0.648
1.27LysPhe: 1.27 ± 0.652
0.423LysGly: 0.423 ± 1.092
0.846LysHis: 0.846 ± 0.435
2.539LysIle: 2.539 ± 1.305
0.846LysLys: 0.846 ± 2.184
5.501LysLeu: 5.501 ± 1.101
0.846LysMet: 0.846 ± 0.356
1.27LysAsn: 1.27 ± 0.657
1.27LysPro: 1.27 ± 0.657
0.423LysGln: 0.423 ± 0.217
1.693LysArg: 1.693 ± 0.439
5.078LysSer: 5.078 ± 2.628
3.386LysThr: 3.386 ± 0.879
0.846LysVal: 0.846 ± 0.435
0.0LysTrp: 0.0 ± 0.0
2.116LysTyr: 2.116 ± 0.222
0.0LysXaa: 0.0 ± 0.0
Leu
5.501LeuAla: 5.501 ± 2.41
3.809LeuCys: 3.809 ± 0.648
5.925LeuAsp: 5.925 ± 1.736
3.809LeuGlu: 3.809 ± 0.648
3.386LeuPhe: 3.386 ± 0.879
8.464LeuGly: 8.464 ± 0.888
4.232LeuHis: 4.232 ± 2.175
8.464LeuIle: 8.464 ± 0.888
5.501LeuLys: 5.501 ± 1.101
12.273LeuLeu: 12.273 ± 4.998
1.693LeuMet: 1.693 ± 0.87
6.348LeuAsn: 6.348 ± 0.644
5.925LeuPro: 5.925 ± 1.736
3.386LeuGln: 3.386 ± 1.74
11.003LeuArg: 11.003 ± 0.892
12.273LeuSer: 12.273 ± 3.689
6.348LeuThr: 6.348 ± 0.644
10.58LeuVal: 10.58 ± 1.11
1.693LeuTrp: 1.693 ± 0.439
5.078LeuTyr: 5.078 ± 2.61
0.0LeuXaa: 0.0 ± 0.0
Met
1.693MetAla: 1.693 ± 1.749
0.0MetCys: 0.0 ± 0.0
1.693MetAsp: 1.693 ± 0.439
0.846MetGlu: 0.846 ± 2.184
0.846MetPhe: 0.846 ± 0.435
1.27MetGly: 1.27 ± 0.652
0.423MetHis: 0.423 ± 0.217
1.693MetIle: 1.693 ± 0.439
0.423MetLys: 0.423 ± 0.217
2.116MetLeu: 2.116 ± 0.222
0.0MetMet: 0.0 ± 0.0
0.846MetAsn: 0.846 ± 0.435
1.27MetPro: 1.27 ± 1.966
0.846MetGln: 0.846 ± 0.435
0.846MetArg: 0.846 ± 0.874
2.539MetSer: 2.539 ± 1.305
1.693MetThr: 1.693 ± 0.87
0.423MetVal: 0.423 ± 0.217
0.423MetTrp: 0.423 ± 0.217
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.539AsnAla: 2.539 ± 1.305
0.423AsnCys: 0.423 ± 0.217
0.846AsnAsp: 0.846 ± 0.435
2.962AsnGlu: 2.962 ± 0.213
2.116AsnPhe: 2.116 ± 1.087
2.962AsnGly: 2.962 ± 1.096
0.423AsnHis: 0.423 ± 0.217
3.386AsnIle: 3.386 ± 0.431
0.423AsnLys: 0.423 ± 1.092
5.078AsnLeu: 5.078 ± 2.61
0.0AsnMet: 0.0 ± 0.0
1.693AsnAsn: 1.693 ± 0.87
2.116AsnPro: 2.116 ± 0.222
0.423AsnGln: 0.423 ± 0.217
2.539AsnArg: 2.539 ± 1.305
1.693AsnSer: 1.693 ± 0.87
0.846AsnThr: 0.846 ± 0.435
2.539AsnVal: 2.539 ± 2.623
0.0AsnTrp: 0.0 ± 0.0
2.539AsnTyr: 2.539 ± 0.004
0.0AsnXaa: 0.0 ± 0.0
Pro
4.655ProAla: 4.655 ± 4.155
0.423ProCys: 0.423 ± 0.217
4.232ProAsp: 4.232 ± 1.753
2.962ProGlu: 2.962 ± 0.213
0.423ProPhe: 0.423 ± 0.217
2.539ProGly: 2.539 ± 0.004
1.27ProHis: 1.27 ± 0.657
4.232ProIle: 4.232 ± 0.866
2.539ProLys: 2.539 ± 0.004
3.386ProLeu: 3.386 ± 0.879
0.846ProMet: 0.846 ± 0.874
2.116ProAsn: 2.116 ± 0.222
3.809ProPro: 3.809 ± 0.661
1.693ProGln: 1.693 ± 0.439
3.809ProArg: 3.809 ± 1.957
5.078ProSer: 5.078 ± 2.628
5.501ProThr: 5.501 ± 0.209
1.27ProVal: 1.27 ± 0.652
0.846ProTrp: 0.846 ± 0.435
1.693ProTyr: 1.693 ± 0.87
0.0ProXaa: 0.0 ± 0.0
Gln
2.539GlnAla: 2.539 ± 1.305
0.0GlnCys: 0.0 ± 0.0
0.846GlnAsp: 0.846 ± 0.874
2.539GlnGlu: 2.539 ± 1.305
2.962GlnPhe: 2.962 ± 1.096
2.116GlnGly: 2.116 ± 0.222
0.0GlnHis: 0.0 ± 0.0
1.693GlnIle: 1.693 ± 0.439
1.27GlnLys: 1.27 ± 0.652
6.348GlnLeu: 6.348 ± 0.666
0.846GlnMet: 0.846 ± 0.435
0.423GlnAsn: 0.423 ± 0.217
1.693GlnPro: 1.693 ± 1.749
1.27GlnGln: 1.27 ± 0.652
0.846GlnArg: 0.846 ± 0.435
2.962GlnSer: 2.962 ± 1.522
0.423GlnThr: 0.423 ± 0.217
2.116GlnVal: 2.116 ± 1.087
0.846GlnTrp: 0.846 ± 0.435
2.539GlnTyr: 2.539 ± 0.004
0.0GlnXaa: 0.0 ± 0.0
Arg
5.925ArgAla: 5.925 ± 0.883
1.27ArgCys: 1.27 ± 0.652
5.925ArgAsp: 5.925 ± 0.426
3.809ArgGlu: 3.809 ± 0.648
0.423ArgPhe: 0.423 ± 0.217
5.925ArgGly: 5.925 ± 2.193
1.693ArgHis: 1.693 ± 0.439
5.501ArgIle: 5.501 ± 2.827
2.539ArgLys: 2.539 ± 1.314
7.617ArgLeu: 7.617 ± 0.013
1.693ArgMet: 1.693 ± 0.439
2.962ArgAsn: 2.962 ± 0.213
0.846ArgPro: 0.846 ± 0.435
2.116ArgGln: 2.116 ± 1.087
5.925ArgArg: 5.925 ± 0.883
4.655ArgSer: 4.655 ± 1.083
2.962ArgThr: 2.962 ± 0.213
7.617ArgVal: 7.617 ± 1.296
0.846ArgTrp: 0.846 ± 0.435
1.693ArgTyr: 1.693 ± 0.87
0.0ArgXaa: 0.0 ± 0.0
Ser
5.501SerAla: 5.501 ± 3.72
0.846SerCys: 0.846 ± 0.435
5.925SerAsp: 5.925 ± 2.193
3.809SerGlu: 3.809 ± 3.28
2.539SerPhe: 2.539 ± 1.305
4.655SerGly: 4.655 ± 2.392
2.962SerHis: 2.962 ± 1.522
3.809SerIle: 3.809 ± 1.957
2.539SerLys: 2.539 ± 0.004
14.388SerLeu: 14.388 ± 4.776
1.693SerMet: 1.693 ± 1.749
2.962SerAsn: 2.962 ± 1.096
5.925SerPro: 5.925 ± 2.193
3.386SerGln: 3.386 ± 1.74
5.925SerArg: 5.925 ± 0.426
6.348SerSer: 6.348 ± 3.262
5.925SerThr: 5.925 ± 1.736
2.962SerVal: 2.962 ± 0.213
1.27SerTrp: 1.27 ± 0.652
3.386SerTyr: 3.386 ± 1.74
0.0SerXaa: 0.0 ± 0.0
Thr
4.655ThrAla: 4.655 ± 0.226
0.846ThrCys: 0.846 ± 0.435
2.539ThrAsp: 2.539 ± 1.314
1.27ThrGlu: 1.27 ± 0.652
2.962ThrPhe: 2.962 ± 0.213
0.846ThrGly: 0.846 ± 0.874
0.423ThrHis: 0.423 ± 0.217
5.925ThrIle: 5.925 ± 1.736
1.693ThrLys: 1.693 ± 0.439
5.925ThrLeu: 5.925 ± 0.426
2.116ThrMet: 2.116 ± 0.222
0.846ThrAsn: 0.846 ± 0.435
2.962ThrPro: 2.962 ± 1.522
1.27ThrGln: 1.27 ± 0.652
4.655ThrArg: 4.655 ± 0.226
6.348ThrSer: 6.348 ± 0.644
3.809ThrThr: 3.809 ± 1.957
2.962ThrVal: 2.962 ± 1.522
1.693ThrTrp: 1.693 ± 0.87
3.809ThrTyr: 3.809 ± 1.971
0.0ThrXaa: 0.0 ± 0.0
Val
4.655ValAla: 4.655 ± 0.226
0.846ValCys: 0.846 ± 0.435
3.386ValAsp: 3.386 ± 1.74
2.116ValGlu: 2.116 ± 2.841
0.846ValPhe: 0.846 ± 0.435
3.386ValGly: 3.386 ± 1.74
2.539ValHis: 2.539 ± 1.314
2.116ValIle: 2.116 ± 1.531
5.078ValLys: 5.078 ± 0.009
8.464ValLeu: 8.464 ± 0.422
0.846ValMet: 0.846 ± 0.874
3.809ValAsn: 3.809 ± 0.648
2.962ValPro: 2.962 ± 1.522
2.539ValGln: 2.539 ± 1.314
4.655ValArg: 4.655 ± 2.845
2.539ValSer: 2.539 ± 0.004
2.539ValThr: 2.539 ± 1.314
4.655ValVal: 4.655 ± 0.226
0.846ValTrp: 0.846 ± 0.874
1.693ValTyr: 1.693 ± 0.87
0.0ValXaa: 0.0 ± 0.0
Trp
0.423TrpAla: 0.423 ± 0.217
0.423TrpCys: 0.423 ± 0.217
0.423TrpAsp: 0.423 ± 0.217
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.846TrpGly: 0.846 ± 0.435
0.0TrpHis: 0.0 ± 0.0
0.423TrpIle: 0.423 ± 1.092
0.846TrpLys: 0.846 ± 0.874
1.27TrpLeu: 1.27 ± 0.657
0.423TrpMet: 0.423 ± 0.217
0.846TrpAsn: 0.846 ± 0.435
0.846TrpPro: 0.846 ± 0.435
0.0TrpGln: 0.0 ± 0.0
1.693TrpArg: 1.693 ± 0.87
1.693TrpSer: 1.693 ± 0.87
1.693TrpThr: 1.693 ± 0.87
0.846TrpVal: 0.846 ± 0.435
0.0TrpTrp: 0.0 ± 0.0
0.423TrpTyr: 0.423 ± 0.217
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.809TyrAla: 3.809 ± 0.648
0.846TyrCys: 0.846 ± 0.435
2.116TyrAsp: 2.116 ± 1.087
1.27TyrGlu: 1.27 ± 0.652
1.27TyrPhe: 1.27 ± 0.652
1.693TyrGly: 1.693 ± 1.749
1.27TyrHis: 1.27 ± 0.652
2.116TyrIle: 2.116 ± 0.222
1.27TyrLys: 1.27 ± 0.657
5.078TyrLeu: 5.078 ± 0.009
0.846TyrMet: 0.846 ± 0.435
0.846TyrAsn: 0.846 ± 0.435
0.846TyrPro: 0.846 ± 0.435
2.539TyrGln: 2.539 ± 0.004
2.539TyrArg: 2.539 ± 1.305
2.539TyrSer: 2.539 ± 1.305
1.27TyrThr: 1.27 ± 0.657
1.27TyrVal: 1.27 ± 0.657
0.846TyrTrp: 0.846 ± 0.435
0.846TyrTyr: 0.846 ± 0.435
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2364 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski