Amino acid dipepetide frequency for Botryotinia fuckeliana (strain T4) (Noble rot fungus) (Botrytis cinerea)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.081AlaAla: 7.081 ± 0.054	0.975AlaCys: 0.975 ± 0.015	3.543AlaAsp: 3.543 ± 0.027	4.647AlaGlu: 4.647 ± 0.04	2.857AlaPhe: 2.857 ± 0.024	5.046AlaGly: 5.046 ± 0.032	1.55AlaHis: 1.55 ± 0.019	4.328AlaIle: 4.328 ± 0.033	4.086AlaLys: 4.086 ± 0.032	6.728AlaLeu: 6.728 ± 0.037	1.839AlaMet: 1.839 ± 0.017	3.036AlaAsn: 3.036 ± 0.024	4.227AlaPro: 4.227 ± 0.038	3.024AlaGln: 3.024 ± 0.029	4.126AlaArg: 4.126 ± 0.03	6.895AlaSer: 6.895 ± 0.049	4.931AlaThr: 4.931 ± 0.032	4.448AlaVal: 4.448 ± 0.034	0.995AlaTrp: 0.995 ± 0.015	2.031AlaTyr: 2.031 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.88CysAla: 0.88 ± 0.014	0.258CysCys: 0.258 ± 0.008	0.646CysAsp: 0.646 ± 0.012	0.648CysGlu: 0.648 ± 0.012	0.545CysPhe: 0.545 ± 0.011	0.963CysGly: 0.963 ± 0.017	0.33CysHis: 0.33 ± 0.007	0.766CysIle: 0.766 ± 0.01	0.613CysLys: 0.613 ± 0.012	1.221CysLeu: 1.221 ± 0.016	0.311CysMet: 0.311 ± 0.008	0.483CysAsn: 0.483 ± 0.009	0.659CysPro: 0.659 ± 0.012	0.448CysGln: 0.448 ± 0.008	0.713CysArg: 0.713 ± 0.013	1.018CysSer: 1.018 ± 0.015	0.731CysThr: 0.731 ± 0.012	0.763CysVal: 0.763 ± 0.013	0.208CysTrp: 0.208 ± 0.007	0.373CysTyr: 0.373 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.005AspAla: 4.005 ± 0.024	0.647AspCys: 0.647 ± 0.01	4.006AspAsp: 4.006 ± 0.045	4.485AspGlu: 4.485 ± 0.042	2.228AspPhe: 2.228 ± 0.019	3.812AspGly: 3.812 ± 0.033	1.167AspHis: 1.167 ± 0.015	3.288AspIle: 3.288 ± 0.027	2.398AspLys: 2.398 ± 0.023	4.833AspLeu: 4.833 ± 0.034	1.247AspMet: 1.247 ± 0.015	2.083AspAsn: 2.083 ± 0.022	2.878AspPro: 2.878 ± 0.026	1.764AspGln: 1.764 ± 0.019	2.748AspArg: 2.748 ± 0.025	4.301AspSer: 4.301 ± 0.032	2.935AspThr: 2.935 ± 0.025	3.374AspVal: 3.374 ± 0.027	0.84AspTrp: 0.84 ± 0.012	1.597AspTyr: 1.597 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.847GluAla: 4.847 ± 0.035	0.653GluCys: 0.653 ± 0.011	4.303GluAsp: 4.303 ± 0.038	6.065GluGlu: 6.065 ± 0.063	2.083GluPhe: 2.083 ± 0.018	3.905GluGly: 3.905 ± 0.033	1.33GluHis: 1.33 ± 0.015	3.722GluIle: 3.722 ± 0.027	4.456GluLys: 4.456 ± 0.04	5.072GluLeu: 5.072 ± 0.035	1.676GluMet: 1.676 ± 0.017	2.912GluAsn: 2.912 ± 0.023	2.547GluPro: 2.547 ± 0.035	2.348GluGln: 2.348 ± 0.023	4.014GluArg: 4.014 ± 0.034	4.753GluSer: 4.753 ± 0.035	3.519GluThr: 3.519 ± 0.027	3.693GluVal: 3.693 ± 0.031	0.911GluTrp: 0.911 ± 0.016	1.751GluTyr: 1.751 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	2.827PheAla: 2.827 ± 0.022	0.581PheCys: 0.581 ± 0.011	2.248PheAsp: 2.248 ± 0.019	2.314PheGlu: 2.314 ± 0.022	1.579PhePhe: 1.579 ± 0.021	2.868PheGly: 2.868 ± 0.03	0.927PheHis: 0.927 ± 0.014	1.934PheIle: 1.934 ± 0.021	1.711PheLys: 1.711 ± 0.019	3.438PheLeu: 3.438 ± 0.033	0.861PheMet: 0.861 ± 0.013	1.604PheAsn: 1.604 ± 0.018	1.998PhePro: 1.998 ± 0.02	1.452PheGln: 1.452 ± 0.017	1.835PheArg: 1.835 ± 0.018	3.139PheSer: 3.139 ± 0.028	2.246PheThr: 2.246 ± 0.021	2.269PheVal: 2.269 ± 0.024	0.638PheTrp: 0.638 ± 0.011	1.111PheTyr: 1.111 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.644GlyAla: 4.644 ± 0.033	0.868GlyCys: 0.868 ± 0.013	3.432GlyAsp: 3.432 ± 0.03	3.85GlyGlu: 3.85 ± 0.032	2.717GlyPhe: 2.717 ± 0.024	5.674GlyGly: 5.674 ± 0.056	1.563GlyHis: 1.563 ± 0.022	3.73GlyIle: 3.73 ± 0.028	3.865GlyLys: 3.865 ± 0.036	5.65GlyLeu: 5.65 ± 0.039	1.727GlyMet: 1.727 ± 0.022	2.936GlyAsn: 2.936 ± 0.031	2.908GlyPro: 2.908 ± 0.027	2.271GlyGln: 2.271 ± 0.027	3.8GlyArg: 3.8 ± 0.026	5.74GlySer: 5.74 ± 0.039	3.96GlyThr: 3.96 ± 0.027	4.171GlyVal: 4.171 ± 0.033	1.123GlyTrp: 1.123 ± 0.016	2.144GlyTyr: 2.144 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.595HisAla: 1.595 ± 0.018	0.344HisCys: 0.344 ± 0.007	1.249HisAsp: 1.249 ± 0.014	1.356HisGlu: 1.356 ± 0.018	0.927HisPhe: 0.927 ± 0.011	1.587HisGly: 1.587 ± 0.018	0.827HisHis: 0.827 ± 0.014	1.29HisIle: 1.29 ± 0.015	1.038HisLys: 1.038 ± 0.015	2.113HisLeu: 2.113 ± 0.019	0.501HisMet: 0.501 ± 0.01	0.973HisAsn: 0.973 ± 0.013	1.545HisPro: 1.545 ± 0.019	1.001HisGln: 1.001 ± 0.012	1.384HisArg: 1.384 ± 0.016	1.972HisSer: 1.972 ± 0.022	1.363HisThr: 1.363 ± 0.016	1.257HisVal: 1.257 ± 0.015	0.309HisTrp: 0.309 ± 0.008	0.689HisTyr: 0.689 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.266IleAla: 4.266 ± 0.031	0.847IleCys: 0.847 ± 0.015	3.15IleAsp: 3.15 ± 0.024	3.407IleGlu: 3.407 ± 0.027	2.256IlePhe: 2.256 ± 0.022	3.429IleGly: 3.429 ± 0.03	1.323IleHis: 1.323 ± 0.017	3.033IleIle: 3.033 ± 0.028	2.7IleLys: 2.7 ± 0.023	5.037IleLeu: 5.037 ± 0.034	1.169IleMet: 1.169 ± 0.017	2.236IleAsn: 2.236 ± 0.025	3.484IlePro: 3.484 ± 0.025	2.131IleGln: 2.131 ± 0.019	2.833IleArg: 2.833 ± 0.022	4.812IleSer: 4.812 ± 0.035	3.315IleThr: 3.315 ± 0.029	3.328IleVal: 3.328 ± 0.027	0.796IleTrp: 0.796 ± 0.013	1.637IleTyr: 1.637 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.243LysAla: 4.243 ± 0.036	0.598LysCys: 0.598 ± 0.011	3.078LysAsp: 3.078 ± 0.03	4.045LysGlu: 4.045 ± 0.035	1.728LysPhe: 1.728 ± 0.018	3.238LysGly: 3.238 ± 0.031	1.217LysHis: 1.217 ± 0.017	2.964LysIle: 2.964 ± 0.022	4.073LysLys: 4.073 ± 0.044	4.453LysLeu: 4.453 ± 0.035	1.239LysMet: 1.239 ± 0.015	2.291LysAsn: 2.291 ± 0.02	2.775LysPro: 2.775 ± 0.031	1.909LysGln: 1.909 ± 0.02	3.61LysArg: 3.61 ± 0.027	4.429LysSer: 4.429 ± 0.038	3.157LysThr: 3.157 ± 0.03	3.065LysVal: 3.065 ± 0.025	0.753LysTrp: 0.753 ± 0.012	1.518LysTyr: 1.518 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	6.779LeuAla: 6.779 ± 0.039	1.201LeuCys: 1.201 ± 0.017	4.759LeuAsp: 4.759 ± 0.031	5.577LeuGlu: 5.577 ± 0.038	3.237LeuPhe: 3.237 ± 0.029	5.558LeuGly: 5.558 ± 0.037	2.096LeuHis: 2.096 ± 0.022	4.225LeuIle: 4.225 ± 0.032	4.629LeuLys: 4.629 ± 0.035	7.816LeuLeu: 7.816 ± 0.052	1.846LeuMet: 1.846 ± 0.019	3.478LeuAsn: 3.478 ± 0.026	5.264LeuPro: 5.264 ± 0.034	3.697LeuGln: 3.697 ± 0.027	5.136LeuArg: 5.136 ± 0.031	7.431LeuSer: 7.431 ± 0.04	4.695LeuThr: 4.695 ± 0.031	4.846LeuVal: 4.846 ± 0.031	1.127LeuTrp: 1.127 ± 0.017	2.308LeuTyr: 2.308 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.125MetAla: 2.125 ± 0.02	0.283MetCys: 0.283 ± 0.007	1.305MetAsp: 1.305 ± 0.018	1.494MetGlu: 1.494 ± 0.017	0.79MetPhe: 0.79 ± 0.014	1.585MetGly: 1.585 ± 0.015	0.508MetHis: 0.508 ± 0.009	1.215MetIle: 1.215 ± 0.015	1.236MetLys: 1.236 ± 0.015	1.777MetLeu: 1.777 ± 0.017	0.648MetMet: 0.648 ± 0.012	1.014MetAsn: 1.014 ± 0.013	1.27MetPro: 1.27 ± 0.015	0.882MetGln: 0.882 ± 0.015	1.267MetArg: 1.267 ± 0.015	2.088MetSer: 2.088 ± 0.021	1.339MetThr: 1.339 ± 0.017	1.307MetVal: 1.307 ± 0.017	0.264MetTrp: 0.264 ± 0.006	0.58MetTyr: 0.58 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.253AsnAla: 3.253 ± 0.025	0.508AsnCys: 0.508 ± 0.009	2.231AsnAsp: 2.231 ± 0.021	2.463AsnGlu: 2.463 ± 0.021	1.678AsnPhe: 1.678 ± 0.019	3.381AsnGly: 3.381 ± 0.032	1.051AsnHis: 1.051 ± 0.014	2.511AsnIle: 2.511 ± 0.023	1.886AsnLys: 1.886 ± 0.022	3.674AsnLeu: 3.674 ± 0.026	0.973AsnMet: 0.973 ± 0.013	1.963AsnAsn: 1.963 ± 0.022	2.637AsnPro: 2.637 ± 0.02	1.59AsnGln: 1.59 ± 0.022	2.113AsnArg: 2.113 ± 0.02	3.693AsnSer: 3.693 ± 0.029	2.696AsnThr: 2.696 ± 0.025	2.452AsnVal: 2.452 ± 0.024	0.604AsnTrp: 0.604 ± 0.011	1.243AsnTyr: 1.243 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.307ProAla: 4.307 ± 0.037	0.507ProCys: 0.507 ± 0.01	2.739ProAsp: 2.739 ± 0.022	3.563ProGlu: 3.563 ± 0.034	1.995ProPhe: 1.995 ± 0.023	3.397ProGly: 3.397 ± 0.025	1.271ProHis: 1.271 ± 0.018	3.031ProIle: 3.031 ± 0.025	2.916ProLys: 2.916 ± 0.032	4.568ProLeu: 4.568 ± 0.028	1.086ProMet: 1.086 ± 0.015	2.433ProAsn: 2.433 ± 0.026	4.588ProPro: 4.588 ± 0.057	2.423ProGln: 2.423 ± 0.03	3.198ProArg: 3.198 ± 0.03	6.055ProSer: 6.055 ± 0.045	4.029ProThr: 4.029 ± 0.031	3.18ProVal: 3.18 ± 0.029	0.672ProTrp: 0.672 ± 0.011	1.509ProTyr: 1.509 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.046GlnAla: 3.046 ± 0.026	0.436GlnCys: 0.436 ± 0.009	1.933GlnAsp: 1.933 ± 0.018	2.419GlnGlu: 2.419 ± 0.028	1.337GlnPhe: 1.337 ± 0.018	2.215GlnGly: 2.215 ± 0.026	1.001GlnHis: 1.001 ± 0.016	2.157GlnIle: 2.157 ± 0.02	2.254GlnLys: 2.254 ± 0.02	3.162GlnLeu: 3.162 ± 0.022	0.936GlnMet: 0.936 ± 0.013	1.913GlnAsn: 1.913 ± 0.022	2.19GlnPro: 2.19 ± 0.025	2.184GlnGln: 2.184 ± 0.041	2.368GlnArg: 2.368 ± 0.021	3.339GlnSer: 3.339 ± 0.032	2.344GlnThr: 2.344 ± 0.022	2.033GlnVal: 2.033 ± 0.019	0.527GlnTrp: 0.527 ± 0.01	1.229GlnTyr: 1.229 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	3.976ArgAla: 3.976 ± 0.027	0.679ArgCys: 0.679 ± 0.013	3.066ArgAsp: 3.066 ± 0.031	3.922ArgGlu: 3.922 ± 0.033	1.988ArgPhe: 1.988 ± 0.018	3.635ArgGly: 3.635 ± 0.033	1.354ArgHis: 1.354 ± 0.017	3.025ArgIle: 3.025 ± 0.023	3.735ArgLys: 3.735 ± 0.031	4.746ArgLeu: 4.746 ± 0.037	1.357ArgMet: 1.357 ± 0.016	2.579ArgAsn: 2.579 ± 0.022	3.025ArgPro: 3.025 ± 0.029	2.319ArgGln: 2.319 ± 0.021	4.499ArgArg: 4.499 ± 0.043	4.733ArgSer: 4.733 ± 0.041	3.083ArgThr: 3.083 ± 0.024	2.995ArgVal: 2.995 ± 0.026	0.81ArgTrp: 0.81 ± 0.013	1.59ArgTyr: 1.59 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.287SerAla: 6.287 ± 0.044	0.96SerCys: 0.96 ± 0.017	4.339SerAsp: 4.339 ± 0.032	4.598SerGlu: 4.598 ± 0.032	3.244SerPhe: 3.244 ± 0.029	5.623SerGly: 5.623 ± 0.039	2.134SerHis: 2.134 ± 0.023	4.962SerIle: 4.962 ± 0.032	4.5SerLys: 4.5 ± 0.034	7.305SerLeu: 7.305 ± 0.043	1.929SerMet: 1.929 ± 0.02	3.911SerAsn: 3.911 ± 0.033	5.696SerPro: 5.696 ± 0.057	3.516SerGln: 3.516 ± 0.028	5.051SerArg: 5.051 ± 0.036	10.228SerSer: 10.228 ± 0.097	6.458SerThr: 6.458 ± 0.051	4.498SerVal: 4.498 ± 0.032	1.118SerTrp: 1.118 ± 0.014	2.292SerTyr: 2.292 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	4.711ThrAla: 4.711 ± 0.033	0.798ThrCys: 0.798 ± 0.013	2.713ThrAsp: 2.713 ± 0.021	3.194ThrGlu: 3.194 ± 0.022	2.382ThrPhe: 2.382 ± 0.023	4.053ThrGly: 4.053 ± 0.034	1.347ThrHis: 1.347 ± 0.019	3.639ThrIle: 3.639 ± 0.029	3.056ThrLys: 3.056 ± 0.025	5.23ThrLeu: 5.23 ± 0.031	1.249ThrMet: 1.249 ± 0.014	2.519ThrAsn: 2.519 ± 0.023	4.477ThrPro: 4.477 ± 0.035	2.196ThrGln: 2.196 ± 0.022	3.017ThrArg: 3.017 ± 0.027	6.225ThrSer: 6.225 ± 0.051	4.667ThrThr: 4.667 ± 0.043	3.409ThrVal: 3.409 ± 0.028	0.817ThrTrp: 0.817 ± 0.012	1.704ThrTyr: 1.704 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.545ValAla: 4.545 ± 0.033	0.775ValCys: 0.775 ± 0.012	3.391ValAsp: 3.391 ± 0.026	3.975ValGlu: 3.975 ± 0.03	2.276ValPhe: 2.276 ± 0.024	3.81ValGly: 3.81 ± 0.028	1.252ValHis: 1.252 ± 0.016	3.026ValIle: 3.026 ± 0.024	3.087ValLys: 3.087 ± 0.03	5.033ValLeu: 5.033 ± 0.032	1.346ValMet: 1.346 ± 0.016	2.263ValAsn: 2.263 ± 0.021	3.221ValPro: 3.221 ± 0.022	2.167ValGln: 2.167 ± 0.02	3.008ValArg: 3.008 ± 0.024	4.548ValSer: 4.548 ± 0.031	3.304ValThr: 3.304 ± 0.025	3.885ValVal: 3.885 ± 0.033	0.793ValTrp: 0.793 ± 0.012	1.625ValTyr: 1.625 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.979TrpAla: 0.979 ± 0.014	0.204TrpCys: 0.204 ± 0.006	0.838TrpAsp: 0.838 ± 0.014	0.886TrpGlu: 0.886 ± 0.013	0.514TrpPhe: 0.514 ± 0.01	0.944TrpGly: 0.944 ± 0.013	0.323TrpHis: 0.323 ± 0.007	0.817TrpIle: 0.817 ± 0.015	0.888TrpLys: 0.888 ± 0.012	1.231TrpLeu: 1.231 ± 0.016	0.393TrpMet: 0.393 ± 0.008	0.682TrpAsn: 0.682 ± 0.011	0.543TrpPro: 0.543 ± 0.009	0.516TrpGln: 0.516 ± 0.009	0.845TrpArg: 0.845 ± 0.014	1.03TrpSer: 1.03 ± 0.014	0.864TrpThr: 0.864 ± 0.013	0.821TrpVal: 0.821 ± 0.013	0.263TrpTrp: 0.263 ± 0.006	0.424TrpTyr: 0.424 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.996TyrAla: 1.996 ± 0.018	0.454TyrCys: 0.454 ± 0.011	1.668TyrAsp: 1.668 ± 0.016	1.652TyrGlu: 1.652 ± 0.017	1.222TyrPhe: 1.222 ± 0.015	2.05TyrGly: 2.05 ± 0.023	0.75TyrHis: 0.75 ± 0.011	1.522TyrIle: 1.522 ± 0.017	1.258TyrLys: 1.258 ± 0.019	2.615TyrLeu: 2.615 ± 0.023	0.645TyrMet: 0.645 ± 0.011	1.29TyrAsn: 1.29 ± 0.015	1.538TyrPro: 1.538 ± 0.017	1.186TyrGln: 1.186 ± 0.016	1.552TyrArg: 1.552 ± 0.019	2.218TyrSer: 2.218 ± 0.018	1.768TyrThr: 1.768 ± 0.017	1.536TyrVal: 1.536 ± 0.017	0.436TyrTrp: 0.436 ± 0.01	0.957TyrTyr: 0.957 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16338 proteins (5777822 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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