Amino acid dipepetide frequency for Candidatus Xiphinematobacter sp. Idaho Grape

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.289AlaAla: 8.289 ± 0.251
1.3AlaCys: 1.3 ± 0.077
3.221AlaAsp: 3.221 ± 0.12
4.808AlaGlu: 4.808 ± 0.141
3.473AlaPhe: 3.473 ± 0.148
5.739AlaGly: 5.739 ± 0.156
1.996AlaHis: 1.996 ± 0.097
6.234AlaIle: 6.234 ± 0.165
3.606AlaLys: 3.606 ± 0.122
9.593AlaLeu: 9.593 ± 0.218
1.905AlaMet: 1.905 ± 0.097
2.341AlaAsn: 2.341 ± 0.105
2.687AlaPro: 2.687 ± 0.114
3.08AlaGln: 3.08 ± 0.105
5.555AlaArg: 5.555 ± 0.148
5.782AlaSer: 5.782 ± 0.141
4.525AlaThr: 4.525 ± 0.145
6.387AlaVal: 6.387 ± 0.172
0.852AlaTrp: 0.852 ± 0.063
2.243AlaTyr: 2.243 ± 0.087
0.0AlaXaa: 0.0 ± 0.0
Cys
1.147CysAla: 1.147 ± 0.069
0.271CysCys: 0.271 ± 0.038
0.597CysAsp: 0.597 ± 0.05
0.805CysGlu: 0.805 ± 0.053
0.68CysPhe: 0.68 ± 0.05
1.351CysGly: 1.351 ± 0.071
0.412CysHis: 0.412 ± 0.042
1.143CysIle: 1.143 ± 0.058
0.648CysLys: 0.648 ± 0.045
1.693CysLeu: 1.693 ± 0.081
0.306CysMet: 0.306 ± 0.035
0.479CysAsn: 0.479 ± 0.039
0.856CysPro: 0.856 ± 0.057
0.507CysGln: 0.507 ± 0.049
1.178CysArg: 1.178 ± 0.074
1.194CysSer: 1.194 ± 0.066
0.915CysThr: 0.915 ± 0.057
0.959CysVal: 0.959 ± 0.066
0.204CysTrp: 0.204 ± 0.026
0.412CysTyr: 0.412 ± 0.043
0.0CysXaa: 0.0 ± 0.0
Asp
3.496AspAla: 3.496 ± 0.13
0.731AspCys: 0.731 ± 0.055
1.21AspAsp: 1.21 ± 0.077
2.027AspGlu: 2.027 ± 0.101
2.235AspPhe: 2.235 ± 0.099
3.15AspGly: 3.15 ± 0.127
0.97AspHis: 0.97 ± 0.064
3.182AspIle: 3.182 ± 0.107
1.595AspLys: 1.595 ± 0.085
4.785AspLeu: 4.785 ± 0.177
0.837AspMet: 0.837 ± 0.061
1.021AspAsn: 1.021 ± 0.064
2.231AspPro: 2.231 ± 0.1
1.312AspGln: 1.312 ± 0.076
2.648AspArg: 2.648 ± 0.132
2.734AspSer: 2.734 ± 0.109
2.098AspThr: 2.098 ± 0.087
2.907AspVal: 2.907 ± 0.121
0.57AspTrp: 0.57 ± 0.05
1.391AspTyr: 1.391 ± 0.077
0.0AspXaa: 0.0 ± 0.0
Glu
5.213GluAla: 5.213 ± 0.173
0.687GluCys: 0.687 ± 0.051
2.53GluAsp: 2.53 ± 0.102
4.867GluGlu: 4.867 ± 0.166
2.231GluPhe: 2.231 ± 0.094
4.36GluGly: 4.36 ± 0.145
1.167GluHis: 1.167 ± 0.068
4.624GluIle: 4.624 ± 0.147
3.932GluLys: 3.932 ± 0.134
5.845GluLeu: 5.845 ± 0.158
1.497GluMet: 1.497 ± 0.079
2.019GluAsn: 2.019 ± 0.1
1.772GluPro: 1.772 ± 0.089
1.999GluGln: 1.999 ± 0.099
4.529GluArg: 4.529 ± 0.138
3.198GluSer: 3.198 ± 0.11
3.084GluThr: 3.084 ± 0.116
4.899GluVal: 4.899 ± 0.132
0.66GluTrp: 0.66 ± 0.052
1.402GluTyr: 1.402 ± 0.078
0.0GluXaa: 0.0 ± 0.0
Phe
2.801PheAla: 2.801 ± 0.096
0.872PheCys: 0.872 ± 0.057
1.854PheAsp: 1.854 ± 0.088
2.188PheGlu: 2.188 ± 0.099
2.267PhePhe: 2.267 ± 0.11
3.351PheGly: 3.351 ± 0.118
1.285PheHis: 1.285 ± 0.063
2.125PheIle: 2.125 ± 0.085
1.202PheLys: 1.202 ± 0.057
5.46PheLeu: 5.46 ± 0.165
0.731PheMet: 0.731 ± 0.056
1.206PheAsn: 1.206 ± 0.075
2.357PhePro: 2.357 ± 0.115
1.811PheGln: 1.811 ± 0.083
2.773PheArg: 2.773 ± 0.097
3.948PheSer: 3.948 ± 0.126
2.035PheThr: 2.035 ± 0.098
2.813PheVal: 2.813 ± 0.109
0.53PheTrp: 0.53 ± 0.047
1.304PheTyr: 1.304 ± 0.087
0.0PheXaa: 0.0 ± 0.0
Gly
5.504GlyAla: 5.504 ± 0.149
1.241GlyCys: 1.241 ± 0.071
3.139GlyAsp: 3.139 ± 0.12
4.239GlyGlu: 4.239 ± 0.134
3.272GlyPhe: 3.272 ± 0.109
5.991GlyGly: 5.991 ± 0.201
1.874GlyHis: 1.874 ± 0.103
5.873GlyIle: 5.873 ± 0.149
4.439GlyLys: 4.439 ± 0.115
6.788GlyLeu: 6.788 ± 0.167
1.98GlyMet: 1.98 ± 0.109
2.494GlyAsn: 2.494 ± 0.104
2.278GlyPro: 2.278 ± 0.095
2.188GlyGln: 2.188 ± 0.087
5.087GlyArg: 5.087 ± 0.16
4.875GlySer: 4.875 ± 0.12
4.133GlyThr: 4.133 ± 0.136
5.771GlyVal: 5.771 ± 0.14
0.966GlyTrp: 0.966 ± 0.074
2.274GlyTyr: 2.274 ± 0.107
0.0GlyXaa: 0.0 ± 0.0
His
2.043HisAla: 2.043 ± 0.099
0.452HisCys: 0.452 ± 0.041
0.731HisAsp: 0.731 ± 0.051
1.065HisGlu: 1.065 ± 0.068
1.198HisPhe: 1.198 ± 0.064
1.858HisGly: 1.858 ± 0.073
0.77HisHis: 0.77 ± 0.057
1.552HisIle: 1.552 ± 0.073
0.841HisLys: 0.841 ± 0.06
3.139HisLeu: 3.139 ± 0.096
0.452HisMet: 0.452 ± 0.039
0.742HisAsn: 0.742 ± 0.052
1.791HisPro: 1.791 ± 0.09
0.86HisGln: 0.86 ± 0.053
1.799HisArg: 1.799 ± 0.084
1.819HisSer: 1.819 ± 0.083
1.375HisThr: 1.375 ± 0.066
1.74HisVal: 1.74 ± 0.094
0.263HisTrp: 0.263 ± 0.032
0.735HisTyr: 0.735 ± 0.054
0.0HisXaa: 0.0 ± 0.0
Ile
5.983IleAla: 5.983 ± 0.157
1.182IleCys: 1.182 ± 0.056
2.687IleAsp: 2.687 ± 0.105
3.783IleGlu: 3.783 ± 0.14
2.789IlePhe: 2.789 ± 0.109
5.087IleGly: 5.087 ± 0.16
1.748IleHis: 1.748 ± 0.092
3.304IleIle: 3.304 ± 0.124
2.102IleLys: 2.102 ± 0.1
7.377IleLeu: 7.377 ± 0.197
1.068IleMet: 1.068 ± 0.071
1.854IleAsn: 1.854 ± 0.082
3.504IlePro: 3.504 ± 0.127
2.632IleGln: 2.632 ± 0.106
4.478IleArg: 4.478 ± 0.124
4.749IleSer: 4.749 ± 0.142
3.367IleThr: 3.367 ± 0.1
4.576IleVal: 4.576 ± 0.153
0.566IleTrp: 0.566 ± 0.047
1.501IleTyr: 1.501 ± 0.073
0.0IleXaa: 0.0 ± 0.0
Lys
3.559LysAla: 3.559 ± 0.125
0.526LysCys: 0.526 ± 0.042
1.972LysAsp: 1.972 ± 0.157
3.292LysGlu: 3.292 ± 0.13
1.701LysPhe: 1.701 ± 0.085
3.166LysGly: 3.166 ± 0.114
0.943LysHis: 0.943 ± 0.054
3.225LysIle: 3.225 ± 0.112
2.781LysLys: 2.781 ± 0.131
4.392LysLeu: 4.392 ± 0.136
1.182LysMet: 1.182 ± 0.064
1.721LysAsn: 1.721 ± 0.079
1.658LysPro: 1.658 ± 0.076
1.497LysGln: 1.497 ± 0.079
3.339LysArg: 3.339 ± 0.115
2.722LysSer: 2.722 ± 0.106
2.428LysThr: 2.428 ± 0.095
3.39LysVal: 3.39 ± 0.116
0.566LysTrp: 0.566 ± 0.047
1.025LysTyr: 1.025 ± 0.068
0.0LysXaa: 0.0 ± 0.0
Leu
9.691LeuAla: 9.691 ± 0.218
1.783LeuCys: 1.783 ± 0.08
4.698LeuAsp: 4.698 ± 0.133
6.91LeuGlu: 6.91 ± 0.171
4.439LeuPhe: 4.439 ± 0.154
8.08LeuGly: 8.08 ± 0.175
2.84LeuHis: 2.84 ± 0.101
5.708LeuIle: 5.708 ± 0.143
4.325LeuLys: 4.325 ± 0.136
12.633LeuLeu: 12.633 ± 0.234
2.109LeuMet: 2.109 ± 0.094
3.249LeuAsn: 3.249 ± 0.124
6.053LeuPro: 6.053 ± 0.192
4.659LeuGln: 4.659 ± 0.138
8.033LeuArg: 8.033 ± 0.188
8.234LeuSer: 8.234 ± 0.196
5.445LeuThr: 5.445 ± 0.155
7.68LeuVal: 7.68 ± 0.169
1.045LeuTrp: 1.045 ± 0.072
2.781LeuTyr: 2.781 ± 0.115
0.0LeuXaa: 0.0 ± 0.0
Met
1.984MetAla: 1.984 ± 0.1
0.216MetCys: 0.216 ± 0.028
1.092MetAsp: 1.092 ± 0.066
1.548MetGlu: 1.548 ± 0.09
0.621MetPhe: 0.621 ± 0.053
1.783MetGly: 1.783 ± 0.093
0.577MetHis: 0.577 ± 0.043
1.025MetIle: 1.025 ± 0.062
1.068MetLys: 1.068 ± 0.086
2.039MetLeu: 2.039 ± 0.103
0.44MetMet: 0.44 ± 0.05
0.703MetAsn: 0.703 ± 0.053
0.943MetPro: 0.943 ± 0.061
0.97MetGln: 0.97 ± 0.062
1.611MetArg: 1.611 ± 0.072
1.434MetSer: 1.434 ± 0.074
1.057MetThr: 1.057 ± 0.069
1.536MetVal: 1.536 ± 0.082
0.13MetTrp: 0.13 ± 0.023
0.299MetTyr: 0.299 ± 0.031
0.0MetXaa: 0.0 ± 0.0
Asn
2.553AsnAla: 2.553 ± 0.084
0.448AsnCys: 0.448 ± 0.042
1.049AsnAsp: 1.049 ± 0.065
1.371AsnGlu: 1.371 ± 0.079
1.497AsnPhe: 1.497 ± 0.071
2.196AsnGly: 2.196 ± 0.136
0.577AsnHis: 0.577 ± 0.046
1.905AsnIle: 1.905 ± 0.09
1.198AsnLys: 1.198 ± 0.062
3.374AsnLeu: 3.374 ± 0.114
0.699AsnMet: 0.699 ± 0.052
0.86AsnAsn: 0.86 ± 0.059
2.023AsnPro: 2.023 ± 0.091
1.033AsnGln: 1.033 ± 0.065
2.058AsnArg: 2.058 ± 0.096
2.125AsnSer: 2.125 ± 0.096
1.721AsnThr: 1.721 ± 0.088
2.223AsnVal: 2.223 ± 0.094
0.503AsnTrp: 0.503 ± 0.044
0.837AsnTyr: 0.837 ± 0.055
0.0AsnXaa: 0.0 ± 0.0
Pro
3.335ProAla: 3.335 ± 0.118
0.66ProCys: 0.66 ± 0.052
2.043ProAsp: 2.043 ± 0.091
2.899ProGlu: 2.899 ± 0.118
2.204ProPhe: 2.204 ± 0.098
3.288ProGly: 3.288 ± 0.107
1.391ProHis: 1.391 ± 0.07
3.17ProIle: 3.17 ± 0.118
2.051ProLys: 2.051 ± 0.111
5.012ProLeu: 5.012 ± 0.131
0.907ProMet: 0.907 ± 0.058
1.477ProAsn: 1.477 ± 0.08
2.208ProPro: 2.208 ± 0.107
1.681ProGln: 1.681 ± 0.078
2.593ProArg: 2.593 ± 0.101
3.642ProSer: 3.642 ± 0.124
2.64ProThr: 2.64 ± 0.094
3.414ProVal: 3.414 ± 0.114
0.522ProTrp: 0.522 ± 0.055
1.281ProTyr: 1.281 ± 0.071
0.0ProXaa: 0.0 ± 0.0
Gln
3.488GlnAla: 3.488 ± 0.118
0.53GlnCys: 0.53 ± 0.042
1.453GlnAsp: 1.453 ± 0.078
2.549GlnGlu: 2.549 ± 0.102
1.453GlnPhe: 1.453 ± 0.069
2.373GlnGly: 2.373 ± 0.101
0.994GlnHis: 0.994 ± 0.061
2.553GlnIle: 2.553 ± 0.096
2.094GlnLys: 2.094 ± 0.095
4.14GlnLeu: 4.14 ± 0.125
0.797GlnMet: 0.797 ± 0.053
1.19GlnAsn: 1.19 ± 0.07
1.618GlnPro: 1.618 ± 0.089
1.583GlnGln: 1.583 ± 0.091
2.569GlnArg: 2.569 ± 0.103
2.341GlnSer: 2.341 ± 0.096
1.795GlnThr: 1.795 ± 0.086
2.746GlnVal: 2.746 ± 0.088
0.46GlnTrp: 0.46 ± 0.046
0.774GlnTyr: 0.774 ± 0.056
0.0GlnXaa: 0.0 ± 0.0
Arg
5.268ArgAla: 5.268 ± 0.146
1.021ArgCys: 1.021 ± 0.062
2.852ArgAsp: 2.852 ± 0.101
4.804ArgGlu: 4.804 ± 0.13
2.821ArgPhe: 2.821 ± 0.101
4.871ArgGly: 4.871 ± 0.146
1.721ArgHis: 1.721 ± 0.073
4.639ArgIle: 4.639 ± 0.135
3.838ArgLys: 3.838 ± 0.156
7.479ArgLeu: 7.479 ± 0.192
1.626ArgMet: 1.626 ± 0.089
2.271ArgAsn: 2.271 ± 0.099
2.597ArgPro: 2.597 ± 0.108
2.738ArgGln: 2.738 ± 0.117
5.602ArgArg: 5.602 ± 0.183
4.274ArgSer: 4.274 ± 0.14
3.245ArgThr: 3.245 ± 0.109
4.957ArgVal: 4.957 ± 0.12
0.845ArgTrp: 0.845 ± 0.065
1.78ArgTyr: 1.78 ± 0.083
0.0ArgXaa: 0.0 ± 0.0
Ser
5.562SerAla: 5.562 ± 0.173
1.092SerCys: 1.092 ± 0.071
2.683SerAsp: 2.683 ± 0.105
3.594SerGlu: 3.594 ± 0.14
3.013SerPhe: 3.013 ± 0.114
5.13SerGly: 5.13 ± 0.157
1.67SerHis: 1.67 ± 0.075
4.569SerIle: 4.569 ± 0.132
3.19SerLys: 3.19 ± 0.128
8.12SerLeu: 8.12 ± 0.21
1.512SerMet: 1.512 ± 0.069
1.921SerAsn: 1.921 ± 0.083
3.567SerPro: 3.567 ± 0.104
2.549SerGln: 2.549 ± 0.1
4.584SerArg: 4.584 ± 0.126
5.684SerSer: 5.684 ± 0.18
3.716SerThr: 3.716 ± 0.132
4.69SerVal: 4.69 ± 0.138
0.892SerTrp: 0.892 ± 0.071
1.921SerTyr: 1.921 ± 0.087
0.0SerXaa: 0.0 ± 0.0
Thr
4.392ThrAla: 4.392 ± 0.124
0.75ThrCys: 0.75 ± 0.06
2.035ThrAsp: 2.035 ± 0.079
2.785ThrGlu: 2.785 ± 0.107
2.212ThrPhe: 2.212 ± 0.091
3.94ThrGly: 3.94 ± 0.115
1.395ThrHis: 1.395 ± 0.069
3.182ThrIle: 3.182 ± 0.123
1.831ThrLys: 1.831 ± 0.089
6.152ThrLeu: 6.152 ± 0.153
0.959ThrMet: 0.959 ± 0.056
1.603ThrAsn: 1.603 ± 0.067
2.989ThrPro: 2.989 ± 0.111
1.937ThrGln: 1.937 ± 0.075
3.15ThrArg: 3.15 ± 0.121
3.583ThrSer: 3.583 ± 0.118
2.813ThrThr: 2.813 ± 0.117
4.278ThrVal: 4.278 ± 0.135
0.57ThrTrp: 0.57 ± 0.046
1.312ThrTyr: 1.312 ± 0.067
0.0ThrXaa: 0.0 ± 0.0
Val
6.607ValAla: 6.607 ± 0.154
1.367ValCys: 1.367 ± 0.08
3.689ValAsp: 3.689 ± 0.132
4.812ValGlu: 4.812 ± 0.145
3.115ValPhe: 3.115 ± 0.11
5.657ValGly: 5.657 ± 0.164
1.964ValHis: 1.964 ± 0.106
4.144ValIle: 4.144 ± 0.127
2.612ValLys: 2.612 ± 0.108
8.069ValLeu: 8.069 ± 0.175
1.265ValMet: 1.265 ± 0.069
1.941ValAsn: 1.941 ± 0.092
3.398ValPro: 3.398 ± 0.115
2.887ValGln: 2.887 ± 0.114
4.765ValArg: 4.765 ± 0.15
4.918ValSer: 4.918 ± 0.145
3.649ValThr: 3.649 ± 0.13
5.834ValVal: 5.834 ± 0.16
0.695ValTrp: 0.695 ± 0.052
1.795ValTyr: 1.795 ± 0.086
0.0ValXaa: 0.0 ± 0.0
Trp
0.656TrpAla: 0.656 ± 0.057
0.177TrpCys: 0.177 ± 0.028
0.499TrpAsp: 0.499 ± 0.042
0.739TrpGlu: 0.739 ± 0.057
0.479TrpPhe: 0.479 ± 0.047
0.825TrpGly: 0.825 ± 0.066
0.259TrpHis: 0.259 ± 0.03
0.927TrpIle: 0.927 ± 0.07
0.845TrpLys: 0.845 ± 0.063
1.269TrpLeu: 1.269 ± 0.08
0.35TrpMet: 0.35 ± 0.035
0.401TrpAsn: 0.401 ± 0.04
0.471TrpPro: 0.471 ± 0.044
0.393TrpGln: 0.393 ± 0.042
0.805TrpArg: 0.805 ± 0.066
0.577TrpSer: 0.577 ± 0.048
0.601TrpThr: 0.601 ± 0.05
0.711TrpVal: 0.711 ± 0.057
0.212TrpTrp: 0.212 ± 0.038
0.216TrpTyr: 0.216 ± 0.031
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.047TyrAla: 2.047 ± 0.092
0.452TyrCys: 0.452 ± 0.036
1.096TyrAsp: 1.096 ± 0.059
1.43TyrGlu: 1.43 ± 0.079
1.214TyrPhe: 1.214 ± 0.075
2.208TyrGly: 2.208 ± 0.086
0.672TyrHis: 0.672 ± 0.056
1.257TyrIle: 1.257 ± 0.072
0.888TyrLys: 0.888 ± 0.054
3.037TyrLeu: 3.037 ± 0.11
0.448TyrMet: 0.448 ± 0.044
0.758TyrAsn: 0.758 ± 0.061
1.414TyrPro: 1.414 ± 0.069
1.186TyrGln: 1.186 ± 0.068
2.09TyrArg: 2.09 ± 0.089
1.827TyrSer: 1.827 ± 0.092
1.226TyrThr: 1.226 ± 0.081
1.673TyrVal: 1.673 ± 0.085
0.361TyrTrp: 0.361 ± 0.04
0.719TyrTyr: 0.719 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 817 proteins (254565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski