Amino acid dipepetide frequency for Hubei picorna-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.191AlaAla: 3.191 ± 0.0
0.709AlaCys: 0.709 ± 0.0
2.837AlaAsp: 2.837 ± 0.0
3.191AlaGlu: 3.191 ± 0.0
2.128AlaPhe: 2.128 ± 0.0
3.191AlaGly: 3.191 ± 0.0
1.418AlaHis: 1.418 ± 0.0
3.191AlaIle: 3.191 ± 0.0
3.191AlaLys: 3.191 ± 0.0
4.255AlaLeu: 4.255 ± 0.0
1.418AlaMet: 1.418 ± 0.0
2.837AlaAsn: 2.837 ± 0.0
2.482AlaPro: 2.482 ± 0.0
1.773AlaGln: 1.773 ± 0.0
2.128AlaArg: 2.128 ± 0.0
4.61AlaSer: 4.61 ± 0.0
2.837AlaThr: 2.837 ± 0.0
2.837AlaVal: 2.837 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
1.773AlaTyr: 1.773 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.355CysAla: 0.355 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.064CysAsp: 1.064 ± 0.0
0.709CysGlu: 0.709 ± 0.0
1.418CysPhe: 1.418 ± 0.0
1.418CysGly: 1.418 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.064CysIle: 1.064 ± 0.0
1.064CysLys: 1.064 ± 0.0
2.482CysLeu: 2.482 ± 0.0
0.355CysMet: 0.355 ± 0.0
0.709CysAsn: 0.709 ± 0.0
0.355CysPro: 0.355 ± 0.0
0.355CysGln: 0.355 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.418CysSer: 1.418 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.064CysVal: 1.064 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.709CysTyr: 0.709 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.128AspAla: 2.128 ± 0.0
0.709AspCys: 0.709 ± 0.0
6.383AspAsp: 6.383 ± 0.0
3.546AspGlu: 3.546 ± 0.0
3.191AspPhe: 3.191 ± 0.0
3.191AspGly: 3.191 ± 0.0
1.418AspHis: 1.418 ± 0.0
2.482AspIle: 2.482 ± 0.0
3.901AspLys: 3.901 ± 0.0
4.255AspLeu: 4.255 ± 0.0
0.709AspMet: 0.709 ± 0.0
3.191AspAsn: 3.191 ± 0.0
3.191AspPro: 3.191 ± 0.0
2.128AspGln: 2.128 ± 0.0
3.191AspArg: 3.191 ± 0.0
3.901AspSer: 3.901 ± 0.0
1.773AspThr: 1.773 ± 0.0
2.837AspVal: 2.837 ± 0.0
1.064AspTrp: 1.064 ± 0.0
3.191AspTyr: 3.191 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.482GluAla: 2.482 ± 0.0
1.064GluCys: 1.064 ± 0.0
3.191GluAsp: 3.191 ± 0.0
7.447GluGlu: 7.447 ± 0.0
4.61GluPhe: 4.61 ± 0.0
3.901GluGly: 3.901 ± 0.0
1.773GluHis: 1.773 ± 0.0
3.901GluIle: 3.901 ± 0.0
3.191GluLys: 3.191 ± 0.0
3.191GluLeu: 3.191 ± 0.0
1.064GluMet: 1.064 ± 0.0
2.482GluAsn: 2.482 ± 0.0
2.482GluPro: 2.482 ± 0.0
3.546GluGln: 3.546 ± 0.0
2.837GluArg: 2.837 ± 0.0
4.255GluSer: 4.255 ± 0.0
6.028GluThr: 6.028 ± 0.0
2.128GluVal: 2.128 ± 0.0
0.709GluTrp: 0.709 ± 0.0
1.773GluTyr: 1.773 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.128PheAla: 2.128 ± 0.0
1.418PheCys: 1.418 ± 0.0
3.191PheAsp: 3.191 ± 0.0
2.482PheGlu: 2.482 ± 0.0
1.773PhePhe: 1.773 ± 0.0
5.674PheGly: 5.674 ± 0.0
0.709PheHis: 0.709 ± 0.0
3.546PheIle: 3.546 ± 0.0
2.837PheLys: 2.837 ± 0.0
4.61PheLeu: 4.61 ± 0.0
0.355PheMet: 0.355 ± 0.0
2.482PheAsn: 2.482 ± 0.0
1.773PhePro: 1.773 ± 0.0
0.355PheGln: 0.355 ± 0.0
2.837PheArg: 2.837 ± 0.0
3.901PheSer: 3.901 ± 0.0
4.255PheThr: 4.255 ± 0.0
1.418PheVal: 1.418 ± 0.0
0.355PheTrp: 0.355 ± 0.0
1.773PheTyr: 1.773 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.546GlyAla: 3.546 ± 0.0
2.128GlyCys: 2.128 ± 0.0
3.546GlyAsp: 3.546 ± 0.0
2.837GlyGlu: 2.837 ± 0.0
2.482GlyPhe: 2.482 ± 0.0
4.255GlyGly: 4.255 ± 0.0
1.418GlyHis: 1.418 ± 0.0
4.255GlyIle: 4.255 ± 0.0
2.128GlyLys: 2.128 ± 0.0
5.319GlyLeu: 5.319 ± 0.0
0.709GlyMet: 0.709 ± 0.0
1.773GlyAsn: 1.773 ± 0.0
0.709GlyPro: 0.709 ± 0.0
2.837GlyGln: 2.837 ± 0.0
2.837GlyArg: 2.837 ± 0.0
5.674GlySer: 5.674 ± 0.0
3.191GlyThr: 3.191 ± 0.0
3.546GlyVal: 3.546 ± 0.0
0.355GlyTrp: 0.355 ± 0.0
4.255GlyTyr: 4.255 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.709HisAla: 0.709 ± 0.0
0.355HisCys: 0.355 ± 0.0
1.418HisAsp: 1.418 ± 0.0
0.709HisGlu: 0.709 ± 0.0
0.709HisPhe: 0.709 ± 0.0
1.064HisGly: 1.064 ± 0.0
1.418HisHis: 1.418 ± 0.0
1.418HisIle: 1.418 ± 0.0
0.709HisLys: 0.709 ± 0.0
3.191HisLeu: 3.191 ± 0.0
0.355HisMet: 0.355 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.709HisPro: 0.709 ± 0.0
0.709HisGln: 0.709 ± 0.0
1.418HisArg: 1.418 ± 0.0
1.064HisSer: 1.064 ± 0.0
0.355HisThr: 0.355 ± 0.0
2.128HisVal: 2.128 ± 0.0
0.355HisTrp: 0.355 ± 0.0
0.709HisTyr: 0.709 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.482IleAla: 2.482 ± 0.0
0.0IleCys: 0.0 ± 0.0
2.837IleAsp: 2.837 ± 0.0
4.61IleGlu: 4.61 ± 0.0
4.965IlePhe: 4.965 ± 0.0
4.255IleGly: 4.255 ± 0.0
1.418IleHis: 1.418 ± 0.0
4.965IleIle: 4.965 ± 0.0
2.837IleLys: 2.837 ± 0.0
4.61IleLeu: 4.61 ± 0.0
2.482IleMet: 2.482 ± 0.0
3.546IleAsn: 3.546 ± 0.0
4.255IlePro: 4.255 ± 0.0
3.901IleGln: 3.901 ± 0.0
3.191IleArg: 3.191 ± 0.0
6.383IleSer: 6.383 ± 0.0
4.61IleThr: 4.61 ± 0.0
2.128IleVal: 2.128 ± 0.0
0.709IleTrp: 0.709 ± 0.0
4.255IleTyr: 4.255 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.482LysAla: 2.482 ± 0.0
0.709LysCys: 0.709 ± 0.0
4.965LysAsp: 4.965 ± 0.0
3.546LysGlu: 3.546 ± 0.0
4.965LysPhe: 4.965 ± 0.0
2.482LysGly: 2.482 ± 0.0
0.0LysHis: 0.0 ± 0.0
3.546LysIle: 3.546 ± 0.0
5.319LysLys: 5.319 ± 0.0
4.61LysLeu: 4.61 ± 0.0
1.418LysMet: 1.418 ± 0.0
2.837LysAsn: 2.837 ± 0.0
2.482LysPro: 2.482 ± 0.0
2.482LysGln: 2.482 ± 0.0
2.128LysArg: 2.128 ± 0.0
5.319LysSer: 5.319 ± 0.0
5.674LysThr: 5.674 ± 0.0
2.837LysVal: 2.837 ± 0.0
0.0LysTrp: 0.0 ± 0.0
2.482LysTyr: 2.482 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.028LeuAla: 6.028 ± 0.0
1.064LeuCys: 1.064 ± 0.0
5.319LeuAsp: 5.319 ± 0.0
4.965LeuGlu: 4.965 ± 0.0
3.901LeuPhe: 3.901 ± 0.0
6.028LeuGly: 6.028 ± 0.0
1.418LeuHis: 1.418 ± 0.0
6.028LeuIle: 6.028 ± 0.0
5.319LeuLys: 5.319 ± 0.0
5.674LeuLeu: 5.674 ± 0.0
0.709LeuMet: 0.709 ± 0.0
6.738LeuAsn: 6.738 ± 0.0
7.092LeuPro: 7.092 ± 0.0
1.773LeuGln: 1.773 ± 0.0
6.383LeuArg: 6.383 ± 0.0
3.191LeuSer: 3.191 ± 0.0
8.865LeuThr: 8.865 ± 0.0
5.674LeuVal: 5.674 ± 0.0
1.064LeuTrp: 1.064 ± 0.0
2.128LeuTyr: 2.128 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.418MetAla: 1.418 ± 0.0
0.355MetCys: 0.355 ± 0.0
2.128MetAsp: 2.128 ± 0.0
1.773MetGlu: 1.773 ± 0.0
1.418MetPhe: 1.418 ± 0.0
0.709MetGly: 0.709 ± 0.0
0.709MetHis: 0.709 ± 0.0
1.773MetIle: 1.773 ± 0.0
1.773MetLys: 1.773 ± 0.0
1.418MetLeu: 1.418 ± 0.0
1.773MetMet: 1.773 ± 0.0
1.773MetAsn: 1.773 ± 0.0
1.418MetPro: 1.418 ± 0.0
1.064MetGln: 1.064 ± 0.0
0.709MetArg: 0.709 ± 0.0
0.709MetSer: 0.709 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.773MetVal: 1.773 ± 0.0
0.355MetTrp: 0.355 ± 0.0
1.064MetTyr: 1.064 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.064AsnAla: 1.064 ± 0.0
0.355AsnCys: 0.355 ± 0.0
4.61AsnAsp: 4.61 ± 0.0
2.837AsnGlu: 2.837 ± 0.0
1.773AsnPhe: 1.773 ± 0.0
3.191AsnGly: 3.191 ± 0.0
1.064AsnHis: 1.064 ± 0.0
3.901AsnIle: 3.901 ± 0.0
2.128AsnLys: 2.128 ± 0.0
5.674AsnLeu: 5.674 ± 0.0
1.773AsnMet: 1.773 ± 0.0
1.773AsnAsn: 1.773 ± 0.0
2.837AsnPro: 2.837 ± 0.0
1.064AsnGln: 1.064 ± 0.0
1.773AsnArg: 1.773 ± 0.0
6.383AsnSer: 6.383 ± 0.0
3.191AsnThr: 3.191 ± 0.0
4.965AsnVal: 4.965 ± 0.0
0.709AsnTrp: 0.709 ± 0.0
2.482AsnTyr: 2.482 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.837ProAla: 2.837 ± 0.0
0.355ProCys: 0.355 ± 0.0
2.128ProAsp: 2.128 ± 0.0
2.482ProGlu: 2.482 ± 0.0
2.837ProPhe: 2.837 ± 0.0
2.482ProGly: 2.482 ± 0.0
0.709ProHis: 0.709 ± 0.0
3.546ProIle: 3.546 ± 0.0
1.418ProLys: 1.418 ± 0.0
5.319ProLeu: 5.319 ± 0.0
2.128ProMet: 2.128 ± 0.0
3.546ProAsn: 3.546 ± 0.0
2.128ProPro: 2.128 ± 0.0
0.709ProGln: 0.709 ± 0.0
1.773ProArg: 1.773 ± 0.0
4.255ProSer: 4.255 ± 0.0
3.901ProThr: 3.901 ± 0.0
3.546ProVal: 3.546 ± 0.0
0.709ProTrp: 0.709 ± 0.0
1.773ProTyr: 1.773 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.482GlnAla: 2.482 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.482GlnAsp: 2.482 ± 0.0
1.418GlnGlu: 1.418 ± 0.0
1.418GlnPhe: 1.418 ± 0.0
1.773GlnGly: 1.773 ± 0.0
0.355GlnHis: 0.355 ± 0.0
2.128GlnIle: 2.128 ± 0.0
2.482GlnLys: 2.482 ± 0.0
2.837GlnLeu: 2.837 ± 0.0
1.418GlnMet: 1.418 ± 0.0
1.418GlnAsn: 1.418 ± 0.0
2.837GlnPro: 2.837 ± 0.0
1.418GlnGln: 1.418 ± 0.0
2.837GlnArg: 2.837 ± 0.0
1.064GlnSer: 1.064 ± 0.0
1.418GlnThr: 1.418 ± 0.0
2.482GlnVal: 2.482 ± 0.0
1.418GlnTrp: 1.418 ± 0.0
1.064GlnTyr: 1.064 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.546ArgAla: 3.546 ± 0.0
0.709ArgCys: 0.709 ± 0.0
1.064ArgAsp: 1.064 ± 0.0
3.191ArgGlu: 3.191 ± 0.0
1.418ArgPhe: 1.418 ± 0.0
1.418ArgGly: 1.418 ± 0.0
0.709ArgHis: 0.709 ± 0.0
5.674ArgIle: 5.674 ± 0.0
3.901ArgLys: 3.901 ± 0.0
2.837ArgLeu: 2.837 ± 0.0
1.773ArgMet: 1.773 ± 0.0
4.255ArgAsn: 4.255 ± 0.0
1.418ArgPro: 1.418 ± 0.0
1.418ArgGln: 1.418 ± 0.0
3.546ArgArg: 3.546 ± 0.0
3.191ArgSer: 3.191 ± 0.0
3.546ArgThr: 3.546 ± 0.0
2.482ArgVal: 2.482 ± 0.0
0.709ArgTrp: 0.709 ± 0.0
2.837ArgTyr: 2.837 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.901SerAla: 3.901 ± 0.0
0.355SerCys: 0.355 ± 0.0
2.128SerAsp: 2.128 ± 0.0
2.837SerGlu: 2.837 ± 0.0
2.837SerPhe: 2.837 ± 0.0
4.61SerGly: 4.61 ± 0.0
1.064SerHis: 1.064 ± 0.0
7.447SerIle: 7.447 ± 0.0
3.901SerLys: 3.901 ± 0.0
10.284SerLeu: 10.284 ± 0.0
1.773SerMet: 1.773 ± 0.0
4.965SerAsn: 4.965 ± 0.0
3.546SerPro: 3.546 ± 0.0
3.191SerGln: 3.191 ± 0.0
2.128SerArg: 2.128 ± 0.0
8.511SerSer: 8.511 ± 0.0
4.61SerThr: 4.61 ± 0.0
8.511SerVal: 8.511 ± 0.0
1.418SerTrp: 1.418 ± 0.0
1.418SerTyr: 1.418 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.255ThrAla: 4.255 ± 0.0
0.709ThrCys: 0.709 ± 0.0
2.128ThrAsp: 2.128 ± 0.0
5.319ThrGlu: 5.319 ± 0.0
2.128ThrPhe: 2.128 ± 0.0
1.773ThrGly: 1.773 ± 0.0
1.418ThrHis: 1.418 ± 0.0
4.255ThrIle: 4.255 ± 0.0
7.801ThrLys: 7.801 ± 0.0
4.965ThrLeu: 4.965 ± 0.0
0.355ThrMet: 0.355 ± 0.0
2.482ThrAsn: 2.482 ± 0.0
4.255ThrPro: 4.255 ± 0.0
2.128ThrGln: 2.128 ± 0.0
2.837ThrArg: 2.837 ± 0.0
5.319ThrSer: 5.319 ± 0.0
8.511ThrThr: 8.511 ± 0.0
3.901ThrVal: 3.901 ± 0.0
0.355ThrTrp: 0.355 ± 0.0
2.837ThrTyr: 2.837 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.61ValAla: 4.61 ± 0.0
1.418ValCys: 1.418 ± 0.0
1.773ValAsp: 1.773 ± 0.0
3.901ValGlu: 3.901 ± 0.0
2.128ValPhe: 2.128 ± 0.0
4.255ValGly: 4.255 ± 0.0
0.709ValHis: 0.709 ± 0.0
3.901ValIle: 3.901 ± 0.0
3.901ValLys: 3.901 ± 0.0
6.383ValLeu: 6.383 ± 0.0
1.418ValMet: 1.418 ± 0.0
4.255ValAsn: 4.255 ± 0.0
2.482ValPro: 2.482 ± 0.0
1.418ValGln: 1.418 ± 0.0
3.546ValArg: 3.546 ± 0.0
5.674ValSer: 5.674 ± 0.0
2.482ValThr: 2.482 ± 0.0
3.546ValVal: 3.546 ± 0.0
0.709ValTrp: 0.709 ± 0.0
1.773ValTyr: 1.773 ± 0.0
0.355ValXaa: 0.355 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.355TrpCys: 0.355 ± 0.0
1.773TrpAsp: 1.773 ± 0.0
1.064TrpGlu: 1.064 ± 0.0
1.418TrpPhe: 1.418 ± 0.0
0.709TrpGly: 0.709 ± 0.0
0.355TrpHis: 0.355 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.355TrpLys: 0.355 ± 0.0
1.064TrpLeu: 1.064 ± 0.0
0.355TrpMet: 0.355 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.355TrpPro: 0.355 ± 0.0
0.709TrpGln: 0.709 ± 0.0
1.064TrpArg: 1.064 ± 0.0
0.709TrpSer: 0.709 ± 0.0
0.709TrpThr: 0.709 ± 0.0
1.064TrpVal: 1.064 ± 0.0
0.355TrpTrp: 0.355 ± 0.0
0.709TrpTyr: 0.709 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.355TyrAla: 0.355 ± 0.0
1.773TyrCys: 1.773 ± 0.0
1.418TyrAsp: 1.418 ± 0.0
3.191TyrGlu: 3.191 ± 0.0
0.355TyrPhe: 0.355 ± 0.0
1.418TyrGly: 1.418 ± 0.0
1.418TyrHis: 1.418 ± 0.0
1.773TyrIle: 1.773 ± 0.0
2.128TyrLys: 2.128 ± 0.0
6.028TyrLeu: 6.028 ± 0.0
1.418TyrMet: 1.418 ± 0.0
2.482TyrAsn: 2.482 ± 0.0
1.773TyrPro: 1.773 ± 0.0
1.773TyrGln: 1.773 ± 0.0
2.482TyrArg: 2.482 ± 0.0
3.901TyrSer: 3.901 ± 0.0
1.773TyrThr: 1.773 ± 0.0
1.773TyrVal: 1.773 ± 0.0
1.773TyrTrp: 1.773 ± 0.0
2.837TyrTyr: 2.837 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.355XaaLeu: 0.355 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2821 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski