Polystyrenella longa

Taxonomy: cellular organisms; Bacteria; PVC group; Planctomycetes; Planctomycetia; Planctomycetales; Planctomycetaceae; Polystyrenella

Average proteome isoelectric point is 5.81

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4607 proteins (isoelectric point calculated using IPC2_protein)

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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A518CTS8|A0A518CTS8_9PLAN Uncharacterized protein OS=Polystyrenella longa OX=2528007 GN=Pla110_43690 PE=4 SV=1
MM1 pKa = 7.63KK2 pKa = 10.09PFFWFEE8 pKa = 3.79SLRR11 pKa = 11.84NKK13 pKa = 9.74LRR15 pKa = 11.84NNTEE19 pKa = 3.3KK20 pKa = 10.8RR21 pKa = 11.84KK22 pKa = 8.78VLKK25 pKa = 10.19RR26 pKa = 11.84HH27 pKa = 5.73RR28 pKa = 11.84VDD30 pKa = 3.35HH31 pKa = 5.8KK32 pKa = 10.81QIPASVEE39 pKa = 4.01SLEE42 pKa = 3.97EE43 pKa = 3.9RR44 pKa = 11.84LLLSVTTTDD53 pKa = 3.98IDD55 pKa = 4.1PNPADD60 pKa = 3.67TSTSATSNVSPEE72 pKa = 4.42SIDD75 pKa = 4.06LQLLLNQSITEE86 pKa = 4.4TVTLTLPTGGIGEE99 pKa = 5.05EE100 pKa = 4.34DD101 pKa = 3.91PQVPTADD108 pKa = 3.48VIFVVDD114 pKa = 5.16EE115 pKa = 4.15SASMGGEE122 pKa = 3.91HH123 pKa = 6.24SWISEE128 pKa = 3.96MVLDD132 pKa = 5.69LEE134 pKa = 5.17TALEE138 pKa = 4.2DD139 pKa = 3.89QGIFNNRR146 pKa = 11.84FALVGYY152 pKa = 9.39LDD154 pKa = 4.1KK155 pKa = 11.6GSVFNMAPSVDD166 pKa = 3.68QISIYY171 pKa = 10.42DD172 pKa = 3.58EE173 pKa = 4.16SGAIVDD179 pKa = 3.5KK180 pKa = 10.49GTVKK184 pKa = 10.47RR185 pKa = 11.84EE186 pKa = 3.68YY187 pKa = 10.61RR188 pKa = 11.84DD189 pKa = 3.9DD190 pKa = 3.97GSGNVGYY197 pKa = 10.72VRR199 pKa = 11.84AEE201 pKa = 4.0FNLPADD207 pKa = 3.66GTYY210 pKa = 10.71YY211 pKa = 11.13AVLNTQQLDD220 pKa = 3.64LLGEE224 pKa = 4.09VSIEE228 pKa = 3.77AEE230 pKa = 4.13NYY232 pKa = 7.46KK233 pKa = 9.17TATTGSLGDD242 pKa = 3.32TWTVEE247 pKa = 4.18DD248 pKa = 4.81NYY250 pKa = 10.66VASSGQQIASGPDD263 pKa = 2.72NGTSYY268 pKa = 11.76GSGSVNNAPRR278 pKa = 11.84LDD280 pKa = 3.57YY281 pKa = 10.97DD282 pKa = 3.76INFDD286 pKa = 3.88EE287 pKa = 4.96ADD289 pKa = 3.69SYY291 pKa = 9.65YY292 pKa = 10.68VWIRR296 pKa = 11.84GEE298 pKa = 4.08RR299 pKa = 11.84PDD301 pKa = 3.69TNGDD305 pKa = 3.62QIHH308 pKa = 6.63FGLNGSRR315 pKa = 11.84ISSINSFNFWEE326 pKa = 4.53NNLGWAEE333 pKa = 4.16AGTRR337 pKa = 11.84ITVPSTGIHH346 pKa = 5.83TLNLWMGEE354 pKa = 3.94DD355 pKa = 4.96GINIDD360 pKa = 5.35KK361 pKa = 10.7IVLTKK366 pKa = 10.76DD367 pKa = 3.14PNFNPTGQGPSEE379 pKa = 4.25SVQDD383 pKa = 3.65QNGVFLQNTSSHH395 pKa = 6.5EE396 pKa = 3.82YY397 pKa = 10.95GFYY400 pKa = 11.08LEE402 pKa = 5.56DD403 pKa = 3.41NSAAITNAALSFDD416 pKa = 3.59TAYY419 pKa = 10.88QGVTTKK425 pKa = 10.96AGIDD429 pKa = 3.3HH430 pKa = 7.3TYY432 pKa = 11.22SFTTGSTTDD441 pKa = 4.04LLFEE445 pKa = 4.78PLSNDD450 pKa = 3.32EE451 pKa = 4.14NYY453 pKa = 9.74EE454 pKa = 3.87WSLSGPSGEE463 pKa = 4.04IVADD467 pKa = 3.54KK468 pKa = 11.03GFNLADD474 pKa = 3.73TLLSATASGTYY485 pKa = 9.49TLTIRR490 pKa = 11.84ATGPTNGPYY499 pKa = 10.75GFRR502 pKa = 11.84LVDD505 pKa = 3.77LTTPASLTTGTTTTATLDD523 pKa = 3.44PVAEE527 pKa = 4.2SKK529 pKa = 10.87VYY531 pKa = 10.56SLAMVAGSQYY541 pKa = 10.89YY542 pKa = 10.42FNEE545 pKa = 4.39TGWDD549 pKa = 3.43GTANARR555 pKa = 11.84WRR557 pKa = 11.84LVDD560 pKa = 4.38DD561 pKa = 4.31NGAVLFDD568 pKa = 4.22SSLSDD573 pKa = 3.53DD574 pKa = 4.46HH575 pKa = 8.72DD576 pKa = 5.9LITATSTATHH586 pKa = 5.52YY587 pKa = 11.01LIVEE591 pKa = 4.36GDD593 pKa = 3.19IHH595 pKa = 5.86EE596 pKa = 4.62TASTARR602 pKa = 11.84SFTFTVEE609 pKa = 4.17DD610 pKa = 3.93LGSVSSATQALTLGTAINSSLTQIGEE636 pKa = 4.01QAHH639 pKa = 4.84YY640 pKa = 9.49TFTLASDD647 pKa = 3.48ALLYY651 pKa = 10.5FDD653 pKa = 5.45SLTNSTYY660 pKa = 11.2LNWSLTGPSGEE671 pKa = 3.82IVVNQDD677 pKa = 2.98FTGGNQVLNLSSGNYY692 pKa = 8.21TLTVDD697 pKa = 3.76GTEE700 pKa = 3.86TAIGSFHH707 pKa = 7.31FNLQSLSTLATTMTPGIAVTDD728 pKa = 3.74TLDD731 pKa = 3.94PEE733 pKa = 4.78TEE735 pKa = 3.9SHH737 pKa = 6.64VYY739 pKa = 9.7QFSAATGGMYY749 pKa = 10.52SFDD752 pKa = 3.81SQSWTGSANASWKK765 pKa = 10.76LVDD768 pKa = 4.16PYY770 pKa = 11.8GNILFDD776 pKa = 3.68EE777 pKa = 4.55TLDD780 pKa = 3.8TDD782 pKa = 3.57VSTLHH787 pKa = 5.49FHH789 pKa = 7.26EE790 pKa = 5.64GGTYY794 pKa = 10.01SLIVEE799 pKa = 4.29GDD801 pKa = 3.42EE802 pKa = 5.29AEE804 pKa = 4.31TSTTPGYY811 pKa = 9.02TINIVAHH818 pKa = 5.83GTDD821 pKa = 3.33TSTPAPLDD829 pKa = 3.45LSQVVSGDD837 pKa = 2.85ISASNEE843 pKa = 3.31QDD845 pKa = 2.86TFTFTVASAGLFAFDD860 pKa = 4.92ALTDD864 pKa = 3.72NGPVRR869 pKa = 11.84WSLTGSTSGTVVSNRR884 pKa = 11.84LFSASNGKK892 pKa = 8.99NVSDD896 pKa = 5.1ANATLNLAAEE906 pKa = 5.04TYY908 pKa = 9.93TLTIDD913 pKa = 4.17ADD915 pKa = 3.88TDD917 pKa = 3.75VTGDD921 pKa = 3.52YY922 pKa = 11.29AFALIDD928 pKa = 4.17LGASATTLTAGTALNPRR945 pKa = 11.84FNSHH949 pKa = 7.26AIKK952 pKa = 10.02PYY954 pKa = 10.74KK955 pKa = 9.37FTATANDD962 pKa = 4.08RR963 pKa = 11.84LHH965 pKa = 6.99LLLNNWTGTTEE976 pKa = 4.24SQWRR980 pKa = 11.84VVDD983 pKa = 3.86DD984 pKa = 4.41AGTVVASADD993 pKa = 3.75LNQGTGAITLTAGGTYY1009 pKa = 10.54YY1010 pKa = 11.46LLLEE1014 pKa = 4.74GDD1016 pKa = 3.5QSEE1019 pKa = 4.68TVLNSSVNVEE1029 pKa = 3.94IEE1031 pKa = 4.18LEE1033 pKa = 4.19EE1034 pKa = 4.32VTTSATLVMSTPTTGNIASVGDD1056 pKa = 3.27KK1057 pKa = 10.86HH1058 pKa = 6.92EE1059 pKa = 4.18YY1060 pKa = 9.96TFTGTEE1066 pKa = 4.01GDD1068 pKa = 3.77TVLVDD1073 pKa = 4.04FTSAATTDD1081 pKa = 3.3HH1082 pKa = 6.73QITLRR1087 pKa = 11.84GPNGEE1092 pKa = 4.21TLFVSNSHH1100 pKa = 6.76PANVGIQVTDD1110 pKa = 4.07LEE1112 pKa = 4.37LSEE1115 pKa = 4.31TGTYY1119 pKa = 10.25QLVISAEE1126 pKa = 4.15DD1127 pKa = 3.54SSTGAYY1133 pKa = 8.39EE1134 pKa = 4.05FQVSVRR1140 pKa = 11.84DD1141 pKa = 4.01DD1142 pKa = 3.56LQMDD1146 pKa = 4.01HH1147 pKa = 6.23EE1148 pKa = 4.9VKK1150 pKa = 10.5GVYY1153 pKa = 10.05DD1154 pKa = 3.19SFYY1157 pKa = 9.2TRR1159 pKa = 11.84EE1160 pKa = 3.89VFKK1163 pKa = 11.22FNGLEE1168 pKa = 4.08GQSIQLKK1175 pKa = 8.11MDD1177 pKa = 3.24AWGTAADD1184 pKa = 4.26FGYY1187 pKa = 10.59AAKK1190 pKa = 10.46RR1191 pKa = 11.84LSTLGGDD1198 pKa = 3.39EE1199 pKa = 4.76DD1200 pKa = 5.02GYY1202 pKa = 11.71NAIEE1206 pKa = 4.73LGLNLLDD1213 pKa = 4.23FRR1215 pKa = 11.84EE1216 pKa = 4.58DD1217 pKa = 3.4ASKK1220 pKa = 10.7HH1221 pKa = 5.65IILITDD1227 pKa = 3.52EE1228 pKa = 5.3DD1229 pKa = 4.51RR1230 pKa = 11.84DD1231 pKa = 3.92NFDD1234 pKa = 4.0NNLTASTLQADD1245 pKa = 5.14LEE1247 pKa = 4.28AQGINLHH1254 pKa = 6.76SILNMQIDD1262 pKa = 3.81STDD1265 pKa = 3.51QVDD1268 pKa = 3.92LALGVNGDD1276 pKa = 4.13SPDD1279 pKa = 3.32SRR1281 pKa = 11.84AYY1283 pKa = 10.61FPDD1286 pKa = 3.98GNGGYY1291 pKa = 9.62ISEE1294 pKa = 4.44PSGGVTFNRR1303 pKa = 11.84YY1304 pKa = 9.21SSPSYY1309 pKa = 10.52EE1310 pKa = 3.95YY1311 pKa = 10.15TSNVDD1316 pKa = 3.4TQVDD1320 pKa = 4.39YY1321 pKa = 11.23INPTLAVEE1329 pKa = 4.26GTIWDD1334 pKa = 3.82LRR1336 pKa = 11.84QLRR1339 pKa = 11.84SGGTLGTTFATALSFQEE1356 pKa = 4.48AFVDD1360 pKa = 4.78VITEE1364 pKa = 4.1EE1365 pKa = 4.43VADD1368 pKa = 4.36HH1369 pKa = 6.45YY1370 pKa = 11.76YY1371 pKa = 11.22SLALSKK1377 pKa = 10.97SGVDD1381 pKa = 4.0FAFSAATFTEE1391 pKa = 4.45EE1392 pKa = 4.06TVSFDD1397 pKa = 3.51VTFTEE1402 pKa = 4.74NGASHH1407 pKa = 7.28IFDD1410 pKa = 3.8LQFIQSGDD1418 pKa = 3.25TANPFGSLPVSLTSNYY1434 pKa = 9.67VKK1436 pKa = 10.49LAEE1439 pKa = 4.12EE1440 pKa = 4.41ADD1442 pKa = 3.96FNTAYY1447 pKa = 11.01SDD1449 pKa = 3.58TFTLDD1454 pKa = 2.69SGTNALALRR1463 pKa = 11.84FNNLNFDD1470 pKa = 3.63TSTVDD1475 pKa = 3.72EE1476 pKa = 4.82INDD1479 pKa = 3.63AFEE1482 pKa = 4.35LALVDD1487 pKa = 4.27SNGDD1491 pKa = 3.64PVVGTILQNRR1501 pKa = 11.84DD1502 pKa = 2.41AFFNYY1507 pKa = 9.89TEE1509 pKa = 4.85GEE1511 pKa = 4.24TPNYY1515 pKa = 9.76GNGVLFEE1522 pKa = 4.34TDD1524 pKa = 2.66ISNSFSTVTVDD1535 pKa = 4.45VSHH1538 pKa = 6.51LTAGTSLTLIARR1550 pKa = 11.84LVNDD1554 pKa = 5.15DD1555 pKa = 4.08NDD1557 pKa = 3.8STTSVIIDD1565 pKa = 3.63PRR1567 pKa = 11.84LLQLDD1572 pKa = 3.83VSPVVNPTTTSPTEE1586 pKa = 4.03ANNTPQTIYY1595 pKa = 9.25PARR1598 pKa = 11.84MEE1600 pKa = 4.78DD1601 pKa = 3.65VTDD1604 pKa = 4.07LTTSSYY1610 pKa = 10.96RR1611 pKa = 11.84ATSFNEE1617 pKa = 4.06EE1618 pKa = 3.76TDD1620 pKa = 3.61VLYY1623 pKa = 11.0SAVEE1627 pKa = 3.9IEE1629 pKa = 4.26NTSAEE1634 pKa = 4.27ILRR1637 pKa = 11.84GPILIGVQNISNVNVSLTNIDD1658 pKa = 3.18GTLPDD1663 pKa = 3.74GTPYY1667 pKa = 11.18YY1668 pKa = 10.42DD1669 pKa = 3.68ISHH1672 pKa = 7.56LLTGDD1677 pKa = 2.78VWDD1680 pKa = 3.94PTEE1683 pKa = 3.99VLSGFSLQFTNSNQVQFDD1701 pKa = 3.72FDD1703 pKa = 4.23LVVYY1707 pKa = 10.11ADD1709 pKa = 3.8YY1710 pKa = 11.02MEE1712 pKa = 5.56TITGAPTVNEE1722 pKa = 4.01GSTYY1726 pKa = 9.72TLNLAVSDD1734 pKa = 4.33FNVSSWVIDD1743 pKa = 3.31WGDD1746 pKa = 3.79GGSSTITGGTLTATHH1761 pKa = 7.31TYY1763 pKa = 11.29ADD1765 pKa = 3.93GPNNYY1770 pKa = 8.72TITSTASDD1778 pKa = 3.43GTLIVDD1784 pKa = 3.89TNDD1787 pKa = 3.16LSVAVANVDD1796 pKa = 3.51PVLTISGAQSVVQDD1810 pKa = 3.3STYY1813 pKa = 10.93PLGLSVTDD1821 pKa = 4.81PGDD1824 pKa = 3.6DD1825 pKa = 3.65TLTEE1829 pKa = 4.19WVIDD1833 pKa = 3.71WGDD1836 pKa = 3.47GTSPQTIPGTSLAVDD1851 pKa = 3.66HH1852 pKa = 6.69VFTSPGAYY1860 pKa = 9.02TITATASDD1868 pKa = 3.73EE1869 pKa = 4.49DD1870 pKa = 3.93GTYY1873 pKa = 10.8SSNSLIVQVGEE1884 pKa = 3.94VFLIEE1889 pKa = 4.01NSHH1892 pKa = 6.14FVVEE1896 pKa = 4.36HH1897 pKa = 6.72RR1898 pKa = 11.84YY1899 pKa = 10.01EE1900 pKa = 4.09FTLDD1904 pKa = 3.0EE1905 pKa = 4.05STAAVEE1911 pKa = 4.22VQTYY1915 pKa = 11.35DD1916 pKa = 4.8LFFDD1920 pKa = 3.93TNDD1923 pKa = 4.34LISINDD1929 pKa = 3.7AFEE1932 pKa = 4.22LALVDD1937 pKa = 4.05SEE1939 pKa = 4.3GDD1941 pKa = 3.87SVVGTIIAGRR1951 pKa = 11.84DD1952 pKa = 2.95AFYY1955 pKa = 11.01NQTEE1959 pKa = 4.33GEE1961 pKa = 4.05LRR1963 pKa = 11.84RR1964 pKa = 11.84LGGGAHH1970 pKa = 6.02YY1971 pKa = 10.56NAGTGAVTIDD1981 pKa = 3.53VSHH1984 pKa = 6.77LAVGTEE1990 pKa = 3.82LTLIARR1996 pKa = 11.84LVNNDD2001 pKa = 4.08DD2002 pKa = 3.78DD2003 pKa = 4.37TTTSVGLGEE2012 pKa = 5.49DD2013 pKa = 3.63LTFLTVSPVVGPTTTTPIPVEE2034 pKa = 4.11TLSQAINLNEE2044 pKa = 4.47LDD2046 pKa = 4.93DD2047 pKa = 4.02VTNSIGVAYY2056 pKa = 8.9TVTSFNEE2063 pKa = 3.81EE2064 pKa = 3.81TDD2066 pKa = 3.34RR2067 pKa = 11.84LTTGIQLTNEE2077 pKa = 3.76GTYY2080 pKa = 9.74SVRR2083 pKa = 11.84GPLLMGINGITAAHH2097 pKa = 5.65VRR2099 pKa = 11.84LEE2101 pKa = 4.12NADD2104 pKa = 3.47VVGPDD2109 pKa = 3.04GTRR2112 pKa = 11.84YY2113 pKa = 10.2YY2114 pKa = 11.08DD2115 pKa = 3.67LSQYY2119 pKa = 11.17LFDD2122 pKa = 4.96EE2123 pKa = 4.2QDD2125 pKa = 2.89SWFEE2129 pKa = 3.8PSEE2132 pKa = 4.32TTTEE2136 pKa = 4.24EE2137 pKa = 3.63IFLTFFNPNHH2147 pKa = 5.98NQFDD2151 pKa = 3.94YY2152 pKa = 11.41DD2153 pKa = 3.64IVVLAKK2159 pKa = 10.68LNSAPLFTTSPVVEE2173 pKa = 4.87VIAGEE2178 pKa = 4.31DD2179 pKa = 3.45YY2180 pKa = 11.1SYY2182 pKa = 11.71DD2183 pKa = 3.49SDD2185 pKa = 4.71AVDD2188 pKa = 3.66PEE2190 pKa = 4.32EE2191 pKa = 6.44DD2192 pKa = 3.44EE2193 pKa = 4.34VTYY2196 pKa = 11.2SLVSGPTGLTIDD2208 pKa = 3.83EE2209 pKa = 4.51TTGIVSWTTSLTDD2222 pKa = 3.48ANSIEE2227 pKa = 4.4SVVIQAQDD2235 pKa = 3.57PYY2237 pKa = 11.58AGTTTQEE2244 pKa = 3.81FSIHH2248 pKa = 5.83VRR2250 pKa = 11.84DD2251 pKa = 4.17TVANRR2256 pKa = 11.84PPRR2259 pKa = 11.84FTSIPVLDD2267 pKa = 4.53AYY2269 pKa = 11.17VGLEE2273 pKa = 3.78YY2274 pKa = 9.93TYY2276 pKa = 10.94QATADD2281 pKa = 4.3DD2282 pKa = 4.86PDD2284 pKa = 5.54GDD2286 pKa = 4.14SLVFAGYY2293 pKa = 8.49EE2294 pKa = 3.84IPGGDD2299 pKa = 3.36FTVGTNGAVIWTPTPDD2315 pKa = 6.28DD2316 pKa = 3.33IDD2318 pKa = 3.61QYY2320 pKa = 11.61FDD2322 pKa = 4.01VEE2324 pKa = 4.28LQVDD2328 pKa = 3.92DD2329 pKa = 5.01GNGGSARR2336 pKa = 11.84QAYY2339 pKa = 9.3QILVHH2344 pKa = 6.86ANPANHH2350 pKa = 7.05DD2351 pKa = 4.48PIIVSDD2357 pKa = 3.9PQTEE2361 pKa = 4.11HH2362 pKa = 7.51RR2363 pKa = 11.84LPAPRR2368 pKa = 11.84NAATGTVSPEE2378 pKa = 4.32LISLLLEE2385 pKa = 4.27EE2386 pKa = 5.58GEE2388 pKa = 4.38TSIEE2392 pKa = 3.98PVFYY2396 pKa = 9.84TSPVGEE2402 pKa = 4.67LSQATDD2408 pKa = 3.09VVFIVDD2414 pKa = 3.94EE2415 pKa = 4.62SGSMTDD2421 pKa = 2.97EE2422 pKa = 4.47HH2423 pKa = 7.1DD2424 pKa = 3.52WLGEE2428 pKa = 4.09MINQLDD2434 pKa = 3.56SHH2436 pKa = 6.95LNSEE2440 pKa = 5.01GISPNYY2446 pKa = 9.13YY2447 pKa = 10.73GLVGYY2452 pKa = 10.2LGTGRR2457 pKa = 11.84AITNEE2462 pKa = 3.54EE2463 pKa = 4.35PYY2465 pKa = 10.43RR2466 pKa = 11.84IRR2468 pKa = 11.84IYY2470 pKa = 11.15DD2471 pKa = 3.6NNNVLVQDD2479 pKa = 4.17LDD2481 pKa = 3.69INASYY2486 pKa = 10.85LSPDD2490 pKa = 2.89IVLPTDD2496 pKa = 4.63GIYY2499 pKa = 10.39TIVVDD2504 pKa = 3.87TEE2506 pKa = 4.2GAAGLTNTNFILTSITDD2523 pKa = 3.74EE2524 pKa = 4.22PVTTSGLDD2532 pKa = 3.25TTYY2535 pKa = 10.67SGSITGVEE2543 pKa = 4.12TVTVNFAASAGQEE2556 pKa = 3.91IFIDD2560 pKa = 3.77TTDD2563 pKa = 3.26VDD2565 pKa = 4.4DD2566 pKa = 6.57SIVLYY2571 pKa = 10.64DD2572 pKa = 3.76IVHH2575 pKa = 6.45EE2576 pKa = 4.36SGKK2579 pKa = 10.1IAMADD2584 pKa = 2.97QDD2586 pKa = 3.86ASVDD2590 pKa = 3.61SGVFSIPRR2598 pKa = 11.84SGNYY2602 pKa = 8.83TLTLKK2607 pKa = 10.11TSDD2610 pKa = 3.43GTSTGDD2616 pKa = 3.3YY2617 pKa = 10.86AFRR2620 pKa = 11.84LVDD2623 pKa = 3.84LTNASTIDD2631 pKa = 3.8TSWSAGTLSGTLEE2644 pKa = 3.93TGYY2647 pKa = 10.32EE2648 pKa = 3.6AEE2650 pKa = 4.51YY2651 pKa = 10.16YY2652 pKa = 10.33QFAGEE2657 pKa = 4.51VGDD2660 pKa = 5.1FLQLDD2665 pKa = 4.04SRR2667 pKa = 11.84STGADD2672 pKa = 2.93TADD2675 pKa = 3.17ITLISPSGSILLDD2688 pKa = 3.64GVDD2691 pKa = 3.92ANSDD2695 pKa = 3.31AGLTILPEE2703 pKa = 4.16EE2704 pKa = 4.25GTYY2707 pKa = 10.84LVVVSNSSAVSASYY2721 pKa = 10.48EE2722 pKa = 4.03FKK2724 pKa = 11.2LNDD2727 pKa = 3.84LSTVPTIDD2735 pKa = 3.53FNTTITGTFDD2745 pKa = 3.12TVASTNIVKK2754 pKa = 10.08FDD2756 pKa = 3.62ASAEE2760 pKa = 4.0EE2761 pKa = 5.38LIDD2764 pKa = 3.82FDD2766 pKa = 3.72VTARR2770 pKa = 11.84TGAANATWEE2779 pKa = 4.19LLSPYY2784 pKa = 9.7GASLFSGEE2792 pKa = 4.35FSSASTSDD2800 pKa = 2.99QTVFATHH2807 pKa = 7.36DD2808 pKa = 3.34GTYY2811 pKa = 10.83YY2812 pKa = 11.43LLLKK2816 pKa = 10.62SSPLDD2821 pKa = 3.67AAGGTYY2827 pKa = 10.15DD2828 pKa = 4.45FQMTTQSVTSTGMSLGTLVSDD2849 pKa = 4.76TISAPGEE2856 pKa = 4.06YY2857 pKa = 9.89DD2858 pKa = 3.02LHH2860 pKa = 6.21TFTLSEE2866 pKa = 4.15TKK2868 pKa = 10.26LVYY2871 pKa = 10.22FDD2873 pKa = 5.28SRR2875 pKa = 11.84TNDD2878 pKa = 3.47PLLNWSLTGPGGTIVDD2894 pKa = 3.78RR2895 pKa = 11.84VRR2897 pKa = 11.84LSEE2900 pKa = 4.61ADD2902 pKa = 3.85GKK2904 pKa = 10.54YY2905 pKa = 10.59LPNDD2909 pKa = 3.33EE2910 pKa = 4.98AALEE2914 pKa = 4.31LTAGTYY2920 pKa = 7.8VVKK2923 pKa = 10.61IAGNGYY2929 pKa = 8.25STGDD2933 pKa = 3.41YY2934 pKa = 10.66EE2935 pKa = 5.19FNLVDD2940 pKa = 3.72LHH2942 pKa = 6.01TANSAVFNEE2951 pKa = 4.04NTYY2954 pKa = 9.27LTLSPGDD2961 pKa = 3.11RR2962 pKa = 11.84SAFRR2966 pKa = 11.84KK2967 pKa = 10.26FSATAGDD2974 pKa = 3.61KK2975 pKa = 11.09LLFEE2979 pKa = 5.58SISATANRR2987 pKa = 11.84GYY2989 pKa = 10.08WRR2991 pKa = 11.84LIDD2994 pKa = 4.0PNGEE2998 pKa = 4.09VVFTRR3003 pKa = 11.84KK3004 pKa = 10.29GEE3006 pKa = 3.97AHH3008 pKa = 6.57GGYY3011 pKa = 9.91HH3012 pKa = 6.79EE3013 pKa = 4.35LTEE3016 pKa = 4.23TGIYY3020 pKa = 8.77TVLIEE3025 pKa = 4.24GRR3027 pKa = 11.84GSNTVNFNFNFKK3039 pKa = 8.68ITPIYY3044 pKa = 8.96MQGTPLTLGATTSGAISVSGEE3065 pKa = 3.31HH3066 pKa = 7.5DD3067 pKa = 3.1IYY3069 pKa = 11.18TFTLTQDD3076 pKa = 3.42ALAHH3080 pKa = 6.42FDD3082 pKa = 4.37PLTADD3087 pKa = 3.93TSLEE3091 pKa = 3.91WTLFGPNGIVNNQSYY3106 pKa = 10.66NFAAYY3111 pKa = 10.23DD3112 pKa = 3.72DD3113 pKa = 5.9DD3114 pKa = 4.33YY3115 pKa = 10.89HH3116 pKa = 7.1QHH3118 pKa = 5.58EE3119 pKa = 4.94SEE3121 pKa = 4.46VNSKK3125 pKa = 10.25VLLDD3129 pKa = 4.51LLPGNYY3135 pKa = 9.01TLMIKK3140 pKa = 10.35DD3141 pKa = 4.19AGSGTPSYY3149 pKa = 11.4SFALRR3154 pKa = 11.84DD3155 pKa = 3.56LWSEE3159 pKa = 4.42TISSATVDD3167 pKa = 3.41GQTINGTLDD3176 pKa = 3.57PGNGTDD3182 pKa = 4.22FYY3184 pKa = 10.88KK3185 pKa = 10.64ISATAGDD3192 pKa = 3.98RR3193 pKa = 11.84LDD3195 pKa = 4.13FVNSGDD3201 pKa = 3.5FYY3203 pKa = 11.52DD3204 pKa = 4.65YY3205 pKa = 11.07IRR3207 pKa = 11.84LLDD3210 pKa = 3.97PDD3212 pKa = 4.12GNIVVDD3218 pKa = 4.15TNANADD3224 pKa = 3.75FLYY3227 pKa = 10.05TAEE3230 pKa = 4.14KK3231 pKa = 9.34TGDD3234 pKa = 3.61YY3235 pKa = 10.66LYY3237 pKa = 11.13LLEE3240 pKa = 5.38GDD3242 pKa = 4.76AYY3244 pKa = 11.25NSATVSYY3251 pKa = 10.01SFSVDD3256 pKa = 3.33LYY3258 pKa = 10.71VPPGPGGGGSPTVTTSSLTLDD3279 pKa = 3.81TNVSDD3284 pKa = 4.96SVATDD3289 pKa = 3.28EE3290 pKa = 4.32VNEE3293 pKa = 4.09YY3294 pKa = 9.76TFTLGGAKK3302 pKa = 9.6SLYY3305 pKa = 9.92FDD3307 pKa = 4.67ARR3309 pKa = 11.84TSSADD3314 pKa = 3.67LSWTLSSTNGGDD3326 pKa = 3.09IVINRR3331 pKa = 11.84SFNQSNADD3339 pKa = 4.33DD3340 pKa = 3.83ISGLDD3345 pKa = 3.34VMLNLPADD3353 pKa = 4.7DD3354 pKa = 3.95YY3355 pKa = 11.64TLTISNSGSSTLTYY3369 pKa = 11.02DD3370 pKa = 4.99FGLLDD3375 pKa = 4.0LASATSHH3382 pKa = 7.37DD3383 pKa = 4.61INSSSHH3389 pKa = 5.35VEE3391 pKa = 3.87YY3392 pKa = 10.86DD3393 pKa = 3.19LSTGYY3398 pKa = 8.49STDD3401 pKa = 2.76IFSFSATAGDD3411 pKa = 3.43IFTFSSQDD3419 pKa = 3.3PGGGGTLDD3427 pKa = 4.26DD3428 pKa = 4.09GLLRR3432 pKa = 11.84VVEE3435 pKa = 4.21PNGNVVLEE3443 pKa = 4.11VNYY3446 pKa = 10.64DD3447 pKa = 3.41SSHH3450 pKa = 5.79TGFVAEE3456 pKa = 4.48TTGTYY3461 pKa = 10.55YY3462 pKa = 10.26ILFEE3466 pKa = 6.03GDD3468 pKa = 3.46DD3469 pKa = 4.48SNDD3472 pKa = 2.94EE3473 pKa = 4.44TYY3475 pKa = 11.29EE3476 pKa = 3.74LTAYY3480 pKa = 8.01KK3481 pKa = 9.69TGTGGTVPSPTSITVGQNIDD3501 pKa = 3.5STISVANEE3509 pKa = 3.02QDD3511 pKa = 3.77YY3512 pKa = 11.63YY3513 pKa = 11.35EE3514 pKa = 4.2FTLANDD3520 pKa = 3.37SLIYY3524 pKa = 10.34FDD3526 pKa = 5.07SFSNTSSIRR3535 pKa = 11.84WDD3537 pKa = 3.48LASGSGLTLDD3547 pKa = 3.47NFNYY3551 pKa = 10.27FSGSDD3556 pKa = 3.47ANNVSDD3562 pKa = 4.32AEE3564 pKa = 4.52VVRR3567 pKa = 11.84SLKK3570 pKa = 10.79AGTYY3574 pKa = 8.74RR3575 pKa = 11.84IKK3577 pKa = 11.07VFGSGSSTGDD3587 pKa = 3.07YY3588 pKa = 11.07SFTLKK3593 pKa = 10.66ALSSGTSTSVDD3604 pKa = 3.03TDD3606 pKa = 3.5VTGLLDD3612 pKa = 4.0PANSTNIYY3620 pKa = 9.68QFSGTAGDD3628 pKa = 4.27RR3629 pKa = 11.84LLFDD3633 pKa = 4.13AQVIGAPTGGKK3644 pKa = 8.2WRR3646 pKa = 11.84LIDD3649 pKa = 3.84PDD3651 pKa = 4.05GAVLFNTNRR3660 pKa = 11.84TADD3663 pKa = 3.74LGVVEE3668 pKa = 4.94LSKK3671 pKa = 10.06TGTFYY3676 pKa = 11.65LLIEE3680 pKa = 4.4GAVNNSPTGTATYY3693 pKa = 9.73EE3694 pKa = 3.57FRR3696 pKa = 11.84IQSEE3700 pKa = 4.76VIQTTALTLGTTVSDD3715 pKa = 5.1AISQIGQKK3723 pKa = 10.07NEE3725 pKa = 3.67YY3726 pKa = 9.34TFTLNSRR3733 pKa = 11.84TSLYY3737 pKa = 10.69FDD3739 pKa = 3.47TLTEE3743 pKa = 4.06NEE3745 pKa = 3.84QLYY3748 pKa = 9.46WKK3750 pKa = 9.11LTGPKK3755 pKa = 10.37GEE3757 pKa = 4.32IVPLTTFSYY3766 pKa = 11.03EE3767 pKa = 4.0DD3768 pKa = 4.97DD3769 pKa = 3.74YY3770 pKa = 11.91HH3771 pKa = 7.89GDD3773 pKa = 3.43PEE3775 pKa = 4.4YY3776 pKa = 11.26DD3777 pKa = 3.36NRR3779 pKa = 11.84NLVIDD3784 pKa = 4.04HH3785 pKa = 6.01TQVKK3789 pKa = 9.49PGDD3792 pKa = 3.79YY3793 pKa = 8.91TLSVQGTSSGNQYY3806 pKa = 9.15STGNYY3811 pKa = 9.19SFKK3814 pKa = 10.96LSDD3817 pKa = 4.18LSDD3820 pKa = 3.7SSSSTVILPGTQVDD3834 pKa = 4.1QTASPSPANGTDD3846 pKa = 2.68IYY3848 pKa = 10.99RR3849 pKa = 11.84FDD3851 pKa = 3.63VQAGEE3856 pKa = 4.61LFHH3859 pKa = 7.1FDD3861 pKa = 3.65SVSVTGDD3868 pKa = 3.17TNGFWRR3874 pKa = 11.84LIEE3877 pKa = 4.29PYY3879 pKa = 8.41GTEE3882 pKa = 3.76VFEE3885 pKa = 5.37LSRR3888 pKa = 11.84NVDD3891 pKa = 3.82DD3892 pKa = 6.36GSAADD3897 pKa = 5.07PIILSIPGTYY3907 pKa = 10.02YY3908 pKa = 11.44LLVEE3912 pKa = 4.58GQAADD3917 pKa = 3.97TVATDD3922 pKa = 2.97YY3923 pKa = 11.43SFNVKK3928 pKa = 10.17RR3929 pKa = 11.84IAEE3932 pKa = 4.17PQLQPSRR3939 pKa = 11.84DD3940 pKa = 3.78ALSLNLDD3947 pKa = 3.57QEE3949 pKa = 4.24ISGTIDD3955 pKa = 3.08QASEE3959 pKa = 3.57PVIYY3963 pKa = 10.57SFSGTKK3969 pKa = 8.91GQRR3972 pKa = 11.84LFYY3975 pKa = 10.77DD3976 pKa = 4.07GLSGNSTYY3984 pKa = 10.94LRR3986 pKa = 11.84AKK3988 pKa = 9.98LVQPNGQNLFDD3999 pKa = 4.21VPANDD4004 pKa = 4.68DD4005 pKa = 3.7SGTFTLTHH4013 pKa = 5.56TGEE4016 pKa = 4.35YY4017 pKa = 10.31EE4018 pKa = 4.46LIIHH4022 pKa = 5.66STGSTGAFSFRR4033 pKa = 11.84MVGIDD4038 pKa = 3.19NTEE4041 pKa = 3.58IATFDD4046 pKa = 3.55QEE4048 pKa = 4.53NVNSISQQNKK4058 pKa = 8.69SNTFVVNGLEE4068 pKa = 4.13GDD4070 pKa = 3.75QFRR4073 pKa = 11.84ITPGFNFYY4081 pKa = 10.33MGDD4084 pKa = 3.39ALDD4087 pKa = 4.14FQDD4090 pKa = 5.29RR4091 pKa = 11.84TDD4093 pKa = 4.15DD4094 pKa = 3.98LNTGGGVEE4102 pKa = 4.81DD4103 pKa = 5.48GYY4105 pKa = 11.74AAIDD4109 pKa = 3.56FALTNFPFRR4118 pKa = 11.84PGAAVNLVLVTDD4130 pKa = 4.21EE4131 pKa = 5.35DD4132 pKa = 4.26RR4133 pKa = 11.84DD4134 pKa = 3.91PFDD4137 pKa = 3.71VSLSYY4142 pKa = 11.22SSILADD4148 pKa = 3.85LEE4150 pKa = 3.99ARR4152 pKa = 11.84GAVLHH4157 pKa = 6.43SVVKK4161 pKa = 10.74HH4162 pKa = 5.58NFSTSPYY4169 pKa = 7.66TGAVIGVDD4177 pKa = 3.92NEE4179 pKa = 3.79GMAYY4183 pKa = 9.53IADD4186 pKa = 3.84GSGGFTTTSGGTATSGYY4203 pKa = 8.31GTTKK4207 pKa = 10.6ADD4209 pKa = 4.17YY4210 pKa = 10.65IDD4212 pKa = 5.34LSWDD4216 pKa = 3.29NSGVAWNLDD4225 pKa = 3.15ILRR4228 pKa = 11.84SGGNSATSFTAAFTEE4243 pKa = 4.09ILADD4247 pKa = 4.55EE4248 pKa = 4.71ITDD4251 pKa = 3.49QLAIEE4256 pKa = 4.79VIPSIEE4262 pKa = 3.8GVTINNLTGVIEE4274 pKa = 4.23SVLAGEE4280 pKa = 4.45TVSFDD4285 pKa = 3.57VEE4287 pKa = 4.39FTGTTEE4293 pKa = 3.94AQSFDD4298 pKa = 3.73LLIVRR4303 pKa = 11.84KK4304 pKa = 9.55NDD4306 pKa = 3.01HH4307 pKa = 7.36DD4308 pKa = 4.3YY4309 pKa = 11.36VLASIPVQINTQYY4322 pKa = 10.71YY4323 pKa = 8.13YY4324 pKa = 11.12NVDD4327 pKa = 4.54AIDD4330 pKa = 4.49PDD4332 pKa = 4.15ADD4334 pKa = 3.28ILSYY4338 pKa = 10.86EE4339 pKa = 4.39LTGEE4343 pKa = 4.13THH4345 pKa = 6.06GAEE4348 pKa = 3.9IDD4350 pKa = 3.54ADD4352 pKa = 3.88SGVLVWEE4359 pKa = 4.35PTAEE4363 pKa = 4.01GVYY4366 pKa = 10.12EE4367 pKa = 3.97FAVLVTDD4374 pKa = 4.46GNGGKK4379 pKa = 7.99DD4380 pKa = 3.31TQTWTVTVGNSQEE4393 pKa = 4.33EE4394 pKa = 4.11NTAPIILEE4402 pKa = 4.25APALTANPGEE4412 pKa = 4.23SFQYY4416 pKa = 10.44QVLAEE4421 pKa = 4.66DD4422 pKa = 4.53ADD4424 pKa = 4.17GDD4426 pKa = 4.38TISYY4430 pKa = 7.66LTQGVPPEE4438 pKa = 4.21GLTIDD4443 pKa = 3.46SHH4445 pKa = 5.96TGLVEE4450 pKa = 3.8WTPTIPGEE4458 pKa = 4.22YY4459 pKa = 9.79EE4460 pKa = 3.42FGLRR4464 pKa = 11.84VSDD4467 pKa = 3.25RR4468 pKa = 11.84RR4469 pKa = 11.84GGVDD4473 pKa = 3.3VEE4475 pKa = 4.71TFTITVNEE4483 pKa = 4.08YY4484 pKa = 9.55PPANRR4489 pKa = 11.84RR4490 pKa = 11.84PIITSTPHH4498 pKa = 5.16YY4499 pKa = 10.09SGVSNEE4505 pKa = 3.98LYY4507 pKa = 10.26RR4508 pKa = 11.84YY4509 pKa = 9.2DD4510 pKa = 4.37AAAIDD4515 pKa = 4.23YY4516 pKa = 9.95DD4517 pKa = 3.85FEE4519 pKa = 5.22PIRR4522 pKa = 11.84FEE4524 pKa = 4.93LVAGPAGMTIDD4535 pKa = 3.79EE4536 pKa = 4.34QTGVLVWNPRR4546 pKa = 11.84DD4547 pKa = 3.52KK4548 pKa = 11.21DD4549 pKa = 3.38LGYY4552 pKa = 10.11IPVGIKK4558 pKa = 10.62VIDD4561 pKa = 3.72TQGGFDD4567 pKa = 3.32TQYY4570 pKa = 10.78FEE4572 pKa = 5.43IVIHH4576 pKa = 5.97SLNEE4580 pKa = 3.66PPEE4583 pKa = 4.4FVSEE4587 pKa = 4.23PSPAMGVNQPWSYY4600 pKa = 10.91QSEE4603 pKa = 4.21AVDD4606 pKa = 3.71PNGDD4610 pKa = 3.36VLAYY4614 pKa = 10.69SLLQGPAGMTVSSDD4628 pKa = 3.29GLVNWTPTTEE4638 pKa = 3.49GSYY4641 pKa = 9.94RR4642 pKa = 11.84VRR4644 pKa = 11.84IQADD4648 pKa = 3.54DD4649 pKa = 3.57QRR4651 pKa = 11.84GGTAYY4656 pKa = 10.48QEE4658 pKa = 4.16FTLTITDD4665 pKa = 3.85NSPTSITSTPEE4676 pKa = 3.38YY4677 pKa = 8.56YY4678 pKa = 10.15TYY4680 pKa = 10.88INEE4683 pKa = 4.63DD4684 pKa = 3.34YY4685 pKa = 9.83TYY4687 pKa = 9.93EE4688 pKa = 4.01ITVDD4692 pKa = 3.97DD4693 pKa = 5.16PDD4695 pKa = 3.98VGDD4698 pKa = 3.95TVTISLDD4705 pKa = 3.63DD4706 pKa = 3.82EE4707 pKa = 4.47SLARR4711 pKa = 11.84GMTLTGSTLSWTPDD4725 pKa = 3.03VLGQFEE4731 pKa = 4.37VRR4733 pKa = 11.84ITATDD4738 pKa = 3.24QDD4740 pKa = 4.24GAGQAQVYY4748 pKa = 8.43HH4749 pKa = 5.65LHH4751 pKa = 5.93VVEE4754 pKa = 4.34EE4755 pKa = 4.8VIRR4758 pKa = 11.84SQPPIFDD4765 pKa = 3.81SSPTGPAVVDD4775 pKa = 3.91EE4776 pKa = 4.34EE4777 pKa = 4.28WTYY4780 pKa = 10.94EE4781 pKa = 4.37IEE4783 pKa = 4.39VTDD4786 pKa = 4.06PDD4788 pKa = 4.02GDD4790 pKa = 4.0EE4791 pKa = 4.83VILSLVSGSFPVGMSLNGTTVSWTPSAVSAGEE4823 pKa = 3.91LVSIQAEE4830 pKa = 4.35DD4831 pKa = 3.44PHH4833 pKa = 8.64GSATIQTFEE4842 pKa = 4.76LPVVSTPEE4850 pKa = 3.8VNNAPVITSIPNVSTPVEE4868 pKa = 3.82EE4869 pKa = 4.45EE4870 pKa = 3.45YY4871 pKa = 10.39RR4872 pKa = 11.84YY4873 pKa = 10.3QIEE4876 pKa = 4.81AYY4878 pKa = 9.95DD4879 pKa = 3.98PNGDD4883 pKa = 3.78PLSYY4887 pKa = 10.52SFSVTDD4893 pKa = 4.21RR4894 pKa = 11.84VASSIGSSLIDD4905 pKa = 3.78GSITDD4910 pKa = 3.65SSLSGGEE4917 pKa = 3.83ATFSITGPTNVVEE4930 pKa = 4.52GTDD4933 pKa = 3.5DD4934 pKa = 3.47ATFTLSYY4941 pKa = 10.43TGLLNEE4947 pKa = 4.6GQTASVDD4954 pKa = 3.77LAHH4957 pKa = 6.87VLDD4960 pKa = 4.23STDD4963 pKa = 3.16ASDD4966 pKa = 4.47YY4967 pKa = 11.4SNSLQAAINDD4977 pKa = 4.61AISGEE4982 pKa = 4.25SLISFDD4988 pKa = 3.43GTTLTFTGASEE4999 pKa = 4.52DD5000 pKa = 4.0PLPGSSEE5007 pKa = 4.37GYY5009 pKa = 10.43AGAATSITSSFTNWSSPTNATGDD5032 pKa = 3.9STGSPASISLNSNQPSEE5049 pKa = 4.21ALAVTDD5055 pKa = 3.67YY5056 pKa = 11.47GLNIPANATITGIQLTLVTTGSEE5079 pKa = 3.98EE5080 pKa = 4.32TGWEE5084 pKa = 4.3DD5085 pKa = 4.45IALTKK5090 pKa = 10.81NGTSGVSYY5098 pKa = 10.53KK5099 pKa = 10.9NSGSSGAWDD5108 pKa = 3.81GGSIVYY5114 pKa = 10.27GGSTDD5119 pKa = 3.06LWGTTWTPAEE5129 pKa = 4.13INSTNFGSLIVVEE5142 pKa = 5.4RR5143 pKa = 11.84YY5144 pKa = 9.97SGTDD5148 pKa = 2.78SFYY5151 pKa = 10.94VYY5153 pKa = 10.34SAEE5156 pKa = 3.72IEE5158 pKa = 4.44VFYY5161 pKa = 7.99EE5162 pKa = 4.32TPTIPQITTTDD5173 pKa = 2.69IDD5175 pKa = 3.88FTLDD5179 pKa = 3.08IADD5182 pKa = 4.49DD5183 pKa = 3.72ATTEE5187 pKa = 4.25GNEE5190 pKa = 3.94QFQITLSNPQTTNASGAALIAGAAATTIIDD5220 pKa = 4.71DD5221 pKa = 4.26EE5222 pKa = 4.64TSSAPIVFNITGGKK5236 pKa = 8.46NASEE5240 pKa = 3.77NSPEE5244 pKa = 3.98NEE5246 pKa = 3.54LDD5248 pKa = 3.38YY5249 pKa = 11.21TIGYY5253 pKa = 7.62TGALTAGDD5261 pKa = 3.43IAQINVLHH5269 pKa = 6.44NLNEE5273 pKa = 4.51TTVSDD5278 pKa = 3.84YY5279 pKa = 11.65DD5280 pKa = 3.82VDD5282 pKa = 4.07VVTAIQNAAAATDD5295 pKa = 3.89GVLFDD5300 pKa = 4.01GTTLTFFGGNDD5311 pKa = 3.63YY5312 pKa = 10.72PSSIDD5317 pKa = 3.67FSVVLADD5324 pKa = 4.1DD5325 pKa = 4.82AEE5327 pKa = 4.54LEE5329 pKa = 4.39STEE5332 pKa = 4.27SFSIEE5337 pKa = 3.86LSQTTGNTSITGLDD5351 pKa = 3.65FTEE5354 pKa = 4.34EE5355 pKa = 5.12GILTWTPDD5363 pKa = 3.59FEE5365 pKa = 5.03SSIDD5369 pKa = 3.74VEE5371 pKa = 4.39ITVSDD5376 pKa = 3.73GRR5378 pKa = 11.84GGSATQTYY5386 pKa = 8.31TLTSYY5391 pKa = 10.67IPNTPPDD5398 pKa = 3.64ISSVPSGPAVVDD5410 pKa = 4.79DD5411 pKa = 3.78EE5412 pKa = 4.47WTYY5415 pKa = 11.53QLDD5418 pKa = 3.75AFDD5421 pKa = 4.53IDD5423 pKa = 4.42EE5424 pKa = 5.32DD5425 pKa = 4.14SLSYY5429 pKa = 11.22ALNASALSSGFTIDD5443 pKa = 4.61ANGLVSWTPTAVGSEE5458 pKa = 3.96AVEE5461 pKa = 3.97ITVSDD5466 pKa = 3.62GRR5468 pKa = 11.84GGIAIQSFTMNAIAEE5483 pKa = 4.47HH5484 pKa = 6.07TLNHH5488 pKa = 6.41APVITSVPEE5497 pKa = 4.1GPAEE5501 pKa = 4.29VGSTWTYY5508 pKa = 11.15NIVATDD5514 pKa = 3.72ADD5516 pKa = 5.16LDD5518 pKa = 3.93PLNYY5522 pKa = 9.42FVSVPAPEE5530 pKa = 4.61APSVVVASIAGSIVDD5545 pKa = 3.9NQSTTSSEE5553 pKa = 3.74ATFAISGDD5561 pKa = 3.48ATVTEE5566 pKa = 5.08DD5567 pKa = 5.08PNDD5570 pKa = 3.88ADD5572 pKa = 4.75GNTANYY5578 pKa = 9.8QVTFTSSLASTEE5590 pKa = 4.16TASVDD5595 pKa = 2.8ISQFLGDD5602 pKa = 3.76TTSGDD5607 pKa = 3.5FSEE5610 pKa = 4.62TMISALTTAANAEE5623 pKa = 4.4SSVSLSGSTLTFQGNGTVSSSAEE5646 pKa = 3.95EE5647 pKa = 4.18EE5648 pKa = 4.09FATAAVADD5656 pKa = 3.98VGAGSEE5662 pKa = 3.84EE5663 pKa = 4.19WANVSYY5669 pKa = 10.74AADD5672 pKa = 3.98GNEE5675 pKa = 3.82STAAHH5680 pKa = 6.29AVLDD5684 pKa = 4.24KK5685 pKa = 11.82YY5686 pKa = 10.7EE5687 pKa = 4.67FPDD5690 pKa = 3.97PLQLTDD5696 pKa = 4.04YY5697 pKa = 10.55DD5698 pKa = 4.3FSIPSTATIEE5708 pKa = 4.76GIKK5711 pKa = 9.27VTVNTSGSNNPMTLTSPIAITKK5733 pKa = 10.4DD5734 pKa = 3.23GTSDD5738 pKa = 3.09AGTPGTTTGTWSGGTVVYY5756 pKa = 10.46GGSSDD5761 pKa = 3.59LWGTTWTAADD5771 pKa = 3.61INSSNFGVIVAPQGSNNGPDD5791 pKa = 3.91YY5792 pKa = 10.38YY5793 pKa = 11.19VHH5795 pKa = 6.3SAKK5798 pKa = 10.15IEE5800 pKa = 3.75ITYY5803 pKa = 10.64EE5804 pKa = 4.07SVTGDD5809 pKa = 3.36GTTVLQFSLPVTNDD5823 pKa = 2.92SEE5825 pKa = 4.74TEE5827 pKa = 3.82EE5828 pKa = 4.35SEE5830 pKa = 5.18AYY5832 pKa = 10.15ALQLSNAQTANTDD5845 pKa = 3.15GVLITQNTTSTTIVDD5860 pKa = 4.54DD5861 pKa = 4.01EE5862 pKa = 4.55TTAAPIVFSITGDD5875 pKa = 3.2TSTTEE5880 pKa = 3.78NTGDD5884 pKa = 3.38VDD5886 pKa = 4.17NNEE5889 pKa = 3.72ATYY5892 pKa = 9.41TISYY5896 pKa = 8.66TGTLAEE5902 pKa = 4.53GEE5904 pKa = 4.4VTRR5907 pKa = 11.84IDD5909 pKa = 3.81VVHH5912 pKa = 6.19VLNDD5916 pKa = 3.65TASADD5921 pKa = 3.9YY5922 pKa = 9.28ITDD5925 pKa = 3.14VVTALTSAAAATSGVDD5941 pKa = 4.12FDD5943 pKa = 4.16GTTLTFYY5950 pKa = 11.14GGGSNPNSIDD5960 pKa = 3.47FTVVLSDD5967 pKa = 4.08DD5968 pKa = 3.77ATSEE5972 pKa = 4.07STEE5975 pKa = 3.92SYY5977 pKa = 10.24RR5978 pKa = 11.84IEE5980 pKa = 4.07LHH5982 pKa = 4.84TTEE5985 pKa = 4.62SPYY5988 pKa = 10.98VPIGMNLTSGGVLTWDD6004 pKa = 3.4STAEE6008 pKa = 4.04TEE6010 pKa = 4.2LDD6012 pKa = 3.14ILITVDD6018 pKa = 4.05DD6019 pKa = 4.38GRR6021 pKa = 11.84GGYY6024 pKa = 7.84ATQSFTLSSVDD6035 pKa = 3.53PNTPPGITSVPTGPAYY6051 pKa = 10.67VDD6053 pKa = 3.73EE6054 pKa = 4.22QWTYY6058 pKa = 9.13QVEE6061 pKa = 4.37AEE6063 pKa = 4.49DD6064 pKa = 5.25LEE6066 pKa = 4.54QATLDD6071 pKa = 3.84FDD6073 pKa = 5.23LDD6075 pKa = 3.76AASVSNGFAIDD6086 pKa = 3.84SNGLITWTPTAVTSEE6101 pKa = 4.35TVEE6104 pKa = 4.11VTVTDD6109 pKa = 4.19GNGGSGTQTFMIDD6122 pKa = 3.57AIVRR6126 pKa = 11.84STIDD6130 pKa = 3.35NAPTITSTPEE6140 pKa = 3.98GPGLTEE6146 pKa = 4.27TLWSYY6151 pKa = 11.14QVTATDD6157 pKa = 4.08PNEE6160 pKa = 4.47DD6161 pKa = 4.18PLTFSLDD6168 pKa = 3.25QDD6170 pKa = 3.9SLNRR6174 pKa = 11.84GMTITDD6180 pKa = 4.07GLVEE6184 pKa = 4.21WTPNTIGGYY6193 pKa = 9.2PIIVSVDD6200 pKa = 3.48DD6201 pKa = 4.1GNGNVVTQSFTLQVIDD6217 pKa = 4.5SSATNSPPAINSSPQGPAYY6236 pKa = 10.65LNNEE6240 pKa = 3.12WSYY6243 pKa = 11.47QVDD6246 pKa = 3.58ATDD6249 pKa = 4.68PDD6251 pKa = 4.99LDD6253 pKa = 4.15PLTYY6257 pKa = 10.82SLDD6260 pKa = 3.95SAGLAAGLQISAGGLITWTPTVEE6283 pKa = 4.16TEE6285 pKa = 3.48ITAVITVEE6293 pKa = 4.16DD6294 pKa = 4.19GKK6296 pKa = 10.88AAYY6299 pKa = 7.49ATQTFTLASINEE6311 pKa = 4.3PPPSNDD6317 pKa = 3.02PPVISSVPGNQVKK6330 pKa = 10.72SGDD6333 pKa = 3.53LYY6335 pKa = 11.01LYY6337 pKa = 10.06QVSAYY6342 pKa = 10.11DD6343 pKa = 3.71PNGDD6347 pKa = 3.6ALIYY6351 pKa = 10.64SLVTAPSSMTISSSGLISWTAGDD6374 pKa = 4.11ADD6376 pKa = 4.26TYY6378 pKa = 10.27SVSVKK6383 pKa = 10.52VEE6385 pKa = 4.13DD6386 pKa = 3.53SSGASVTQTYY6396 pKa = 7.95TLHH6399 pKa = 7.17VLEE6402 pKa = 4.96EE6403 pKa = 4.18RR6404 pKa = 11.84PPLEE6408 pKa = 4.27EE6409 pKa = 4.48NEE6411 pKa = 4.38PPVITSTPTGPTALNRR6427 pKa = 11.84GYY6429 pKa = 10.37QYY6431 pKa = 9.84QTIASDD6437 pKa = 3.5ANQDD6441 pKa = 3.77VITFSLDD6448 pKa = 3.19QNSLGRR6454 pKa = 11.84GATIDD6459 pKa = 3.81SEE6461 pKa = 4.58TGLIEE6466 pKa = 3.95WTPITAGTFEE6476 pKa = 4.35FTVTATDD6483 pKa = 3.68PFGASDD6489 pKa = 3.81SQTFSLPVVDD6499 pKa = 5.15NAPPYY6504 pKa = 9.16ITSKK6508 pKa = 9.93PDD6510 pKa = 2.69QYY6512 pKa = 11.27TDD6514 pKa = 2.86MDD6516 pKa = 3.75VEE6518 pKa = 4.07YY6519 pKa = 8.81TYY6521 pKa = 11.51AVTAQDD6527 pKa = 4.6PNPGDD6532 pKa = 3.78TITYY6536 pKa = 9.63SLSSPLSGMSIDD6548 pKa = 3.7AQTGQFSWTPSSIGVFRR6565 pKa = 11.84VNIIVTDD6572 pKa = 3.73NVGASSGQSFDD6583 pKa = 5.04LVVSDD6588 pKa = 5.35PSTPNQNPSIISSPRR6603 pKa = 11.84TSIQLGTSFVHH6614 pKa = 6.23QVIATDD6620 pKa = 4.27PDD6622 pKa = 4.26FDD6624 pKa = 4.45DD6625 pKa = 5.43LNYY6628 pKa = 11.05SLLASAPGGMVIDD6641 pKa = 3.99NGGLITWTPDD6651 pKa = 3.17GEE6653 pKa = 4.67DD6654 pKa = 3.52VATSPHH6660 pKa = 6.74SYY6662 pKa = 8.43TVRR6665 pKa = 11.84VEE6667 pKa = 4.24DD6668 pKa = 3.42GHH6670 pKa = 8.47GGFTEE6675 pKa = 3.88QTYY6678 pKa = 10.69LLSVVTSEE6686 pKa = 4.46VNSAPAITSTPSVNATTGLGYY6707 pKa = 10.32DD6708 pKa = 3.81YY6709 pKa = 10.82QAAATDD6715 pKa = 4.12PEE6717 pKa = 5.41ADD6719 pKa = 3.53SLVWNLNNGPTGMQIDD6735 pKa = 4.4SEE6737 pKa = 4.5TGYY6740 pKa = 11.16LSWSPNLNQIGQHH6753 pKa = 5.87DD6754 pKa = 4.36VSLTVTDD6761 pKa = 4.15TYY6763 pKa = 11.46GGNSTQTYY6771 pKa = 7.65TLTVRR6776 pKa = 11.84SSNLAPMIDD6785 pKa = 3.44SFPITEE6791 pKa = 5.41AIANTAYY6798 pKa = 10.51YY6799 pKa = 9.09YY6800 pKa = 10.67QVDD6803 pKa = 4.12AYY6805 pKa = 10.78DD6806 pKa = 4.26PDD6808 pKa = 4.32GDD6810 pKa = 4.31EE6811 pKa = 4.07ITYY6814 pKa = 11.01SLAAYY6819 pKa = 8.51PSGMTINATSGMINWTPAGSGSVNVIVRR6847 pKa = 11.84VTDD6850 pKa = 3.34ARR6852 pKa = 11.84GASVDD6857 pKa = 3.35QSYY6860 pKa = 8.34TLVVAAPATNEE6871 pKa = 3.87PPQFASTPPSLALVGTLYY6889 pKa = 9.75THH6891 pKa = 7.81ALQTTDD6897 pKa = 4.05PNNDD6901 pKa = 2.9TVTFEE6906 pKa = 4.68LLNGPTSMSIDD6917 pKa = 3.67TNTGLIEE6924 pKa = 4.06WTPASASSNWEE6935 pKa = 3.99PIRR6938 pKa = 11.84IRR6940 pKa = 11.84ISDD6943 pKa = 3.54GTYY6946 pKa = 9.84LVSKK6950 pKa = 8.68TFYY6953 pKa = 10.6VKK6955 pKa = 10.57ARR6957 pKa = 11.84ANSAPAIAAINDD6969 pKa = 3.51KK6970 pKa = 10.09TISAGKK6976 pKa = 9.39SFRR6979 pKa = 11.84VDD6981 pKa = 3.33VNASDD6986 pKa = 4.67PDD6988 pKa = 3.9GDD6990 pKa = 4.52PIFYY6994 pKa = 10.6SLTTAPDD7001 pKa = 3.54GATVDD7006 pKa = 3.56DD7007 pKa = 5.15FGRR7010 pKa = 11.84ILWTTDD7016 pKa = 2.64SSDD7019 pKa = 3.51VGTHH7023 pKa = 6.17PVTVTVTDD7031 pKa = 4.05LLGVSTSEE7039 pKa = 4.18TFDD7042 pKa = 3.0ITVNADD7048 pKa = 3.45TEE7050 pKa = 4.86VPFVNLYY7057 pKa = 10.17IDD7059 pKa = 4.19TYY7061 pKa = 11.17PNGNLGTEE7069 pKa = 4.18VRR7071 pKa = 11.84LQLYY7075 pKa = 10.8ANDD7078 pKa = 3.58NVAIASKK7085 pKa = 9.04TLNLASITVGGTTTPINRR7103 pKa = 11.84VLVLDD7108 pKa = 4.04SNGWTTLTLDD7118 pKa = 4.82QIGTLNFEE7126 pKa = 4.13GTAVDD7131 pKa = 3.6LAGNVGTATPISLQVVDD7148 pKa = 4.84PADD7151 pKa = 3.61VLPPSVNILLPDD7163 pKa = 3.36SDD7165 pKa = 5.77AILTEE7170 pKa = 4.05PTDD7173 pKa = 3.82VIGSVDD7179 pKa = 3.99DD7180 pKa = 5.62DD7181 pKa = 3.98IPASVSWTLTLNSLDD7196 pKa = 3.53GSISKK7201 pKa = 10.16EE7202 pKa = 3.88LGTGTGALSNAVLGEE7217 pKa = 3.9IDD7219 pKa = 3.79TTLLPNGTYY7228 pKa = 11.13ALTLDD7233 pKa = 3.91AVDD7236 pKa = 4.6NGAHH7240 pKa = 6.07SASEE7244 pKa = 3.88TTYY7247 pKa = 10.75IEE7249 pKa = 3.81IEE7251 pKa = 4.21GALKK7255 pKa = 10.63LGNFSVSFLDD7265 pKa = 3.88LAVPVAGIPITITRR7279 pKa = 11.84TYY7281 pKa = 10.0DD7282 pKa = 3.03TLNANKK7288 pKa = 10.05QGDD7291 pKa = 3.91FGYY7294 pKa = 10.77GWNLDD7299 pKa = 3.38ISNVKK7304 pKa = 10.05VDD7306 pKa = 3.23VDD7308 pKa = 4.05YY7309 pKa = 11.77VSGVPQEE7316 pKa = 4.36SSLGDD7321 pKa = 4.08DD7322 pKa = 3.51IYY7324 pKa = 11.46YY7325 pKa = 9.75PQDD7328 pKa = 3.05TRR7330 pKa = 11.84IVITMPDD7337 pKa = 3.41GSTEE7341 pKa = 4.04GFTLYY7346 pKa = 10.27YY7347 pKa = 10.87APDD7350 pKa = 4.28AEE7352 pKa = 4.55TAIPIYY7358 pKa = 10.81GPMYY7362 pKa = 9.38WIPKK7366 pKa = 7.82FQSDD7370 pKa = 4.35SGNQTEE7376 pKa = 4.5LVVPEE7381 pKa = 4.52ILLQQVEE7388 pKa = 4.52GEE7390 pKa = 4.3MYY7392 pKa = 10.89LPGTLTGYY7400 pKa = 10.75NPTLSEE7406 pKa = 4.14FGGGFTLKK7414 pKa = 10.26YY7415 pKa = 10.53RR7416 pKa = 11.84NDD7418 pKa = 3.45AEE7420 pKa = 4.55LFIDD7424 pKa = 5.37GDD7426 pKa = 4.32DD7427 pKa = 4.38LQLSTIKK7434 pKa = 10.98DD7435 pKa = 3.24SDD7437 pKa = 3.79GNKK7440 pKa = 10.25LFFTEE7445 pKa = 4.33TGITSDD7451 pKa = 3.08SGRR7454 pKa = 11.84GIEE7457 pKa = 4.98FEE7459 pKa = 3.82RR7460 pKa = 11.84DD7461 pKa = 2.81QAGRR7465 pKa = 11.84IKK7467 pKa = 10.84AVIDD7471 pKa = 3.54PLGNRR7476 pKa = 11.84ITYY7479 pKa = 8.09TYY7481 pKa = 10.0NANGDD7486 pKa = 4.65LIAVTDD7492 pKa = 3.94RR7493 pKa = 11.84VEE7495 pKa = 3.84ATTQFTYY7502 pKa = 10.83LDD7504 pKa = 3.77EE7505 pKa = 6.55SGDD7508 pKa = 3.62PAHH7511 pKa = 6.65YY7512 pKa = 9.83LDD7514 pKa = 6.21EE7515 pKa = 6.19IIAPNGLPAARR7526 pKa = 11.84SEE7528 pKa = 3.95YY7529 pKa = 10.91DD7530 pKa = 3.01EE7531 pKa = 4.41TGRR7534 pKa = 11.84LTKK7537 pKa = 10.74VIDD7540 pKa = 3.94ADD7542 pKa = 3.87GQTILLDD7549 pKa = 3.63YY7550 pKa = 11.27DD7551 pKa = 3.79SDD7553 pKa = 3.91LKK7555 pKa = 11.36KK7556 pKa = 10.46EE7557 pKa = 4.06VRR7559 pKa = 11.84TDD7561 pKa = 3.32QLDD7564 pKa = 4.36EE7565 pKa = 4.51IWTTWYY7571 pKa = 10.25DD7572 pKa = 3.5DD7573 pKa = 3.56NGNVIRR7579 pKa = 11.84TEE7581 pKa = 4.2DD7582 pKa = 3.84PLGGIVIMTYY7592 pKa = 11.06NDD7594 pKa = 3.8DD7595 pKa = 4.47DD7596 pKa = 4.47LVLSEE7601 pKa = 4.11TRR7603 pKa = 11.84VIGSEE7608 pKa = 3.76DD7609 pKa = 3.5DD7610 pKa = 3.94GVNGEE7615 pKa = 4.23TDD7617 pKa = 4.01DD7618 pKa = 3.61LTTYY7622 pKa = 8.63YY7623 pKa = 10.02TYY7625 pKa = 11.08KK7626 pKa = 10.98ANGDD7630 pKa = 3.7PRR7632 pKa = 11.84TVTDD7636 pKa = 3.27IFGNTSQSFYY7646 pKa = 11.24NPDD7649 pKa = 2.98GFLYY7653 pKa = 10.35QQVDD7657 pKa = 3.37TFGNVTRR7664 pKa = 11.84YY7665 pKa = 9.44SQSPYY7670 pKa = 10.89GSGNKK7675 pKa = 9.04QSVTDD7680 pKa = 3.87PFGNTTTITQTADD7693 pKa = 2.96GGGNRR7698 pKa = 11.84YY7699 pKa = 10.0DD7700 pKa = 5.36LIEE7703 pKa = 4.66DD7704 pKa = 3.32QNGNITRR7711 pKa = 11.84IDD7713 pKa = 3.63YY7714 pKa = 10.88NSYY7717 pKa = 10.71GDD7719 pKa = 3.77VIKK7722 pKa = 10.03TSGSLGSPVTFTIDD7736 pKa = 4.23DD7737 pKa = 4.24LGNQIGTSVIWVNPDD7752 pKa = 2.95NPTDD7756 pKa = 3.43THH7758 pKa = 5.97TLSSSTEE7765 pKa = 3.67YY7766 pKa = 10.87DD7767 pKa = 3.24DD7768 pKa = 3.82QGRR7771 pKa = 11.84VFHH7774 pKa = 6.1TTDD7777 pKa = 2.99AQGNEE7782 pKa = 3.4SWTNYY7787 pKa = 9.88NNIGQVASTTNDD7799 pKa = 3.26LGQSTYY7805 pKa = 11.25YY7806 pKa = 10.75LYY7808 pKa = 10.53DD7809 pKa = 3.09ARR7811 pKa = 11.84GQVVMSINHH7820 pKa = 6.93DD7821 pKa = 3.17GSYY7824 pKa = 10.08SQTVFDD7830 pKa = 4.09AKK7832 pKa = 10.77GRR7834 pKa = 11.84STHH7837 pKa = 6.14SASTNYY7843 pKa = 10.54AGLSRR7848 pKa = 11.84GGSHH7852 pKa = 7.54SIYY7855 pKa = 10.39DD7856 pKa = 3.5ALDD7859 pKa = 3.34RR7860 pKa = 11.84VITSEE7865 pKa = 4.51SRR7867 pKa = 11.84DD7868 pKa = 3.7DD7869 pKa = 3.63LTIQLVDD7876 pKa = 3.65ANEE7879 pKa = 3.96VAFNVSINAQGKK7891 pKa = 9.92LIDD7894 pKa = 4.81DD7895 pKa = 4.05ATSLEE7900 pKa = 4.0VDD7902 pKa = 3.87LDD7904 pKa = 4.56AIFGTIVTNAGTVTDD7919 pKa = 4.11SSSTVYY7925 pKa = 10.88DD7926 pKa = 4.57PISGRR7931 pKa = 11.84MLSTSNFDD7939 pKa = 3.83GDD7941 pKa = 3.96TTTYY7945 pKa = 10.36EE7946 pKa = 4.29YY7947 pKa = 11.22NEE7949 pKa = 4.64KK7950 pKa = 9.95SQQSAVEE7957 pKa = 4.32SVSDD7961 pKa = 4.6GITRR7965 pKa = 11.84RR7966 pKa = 11.84SEE7968 pKa = 3.88TEE7970 pKa = 3.29YY7971 pKa = 11.34DD7972 pKa = 3.36EE7973 pKa = 5.41FGRR7976 pKa = 11.84TYY7978 pKa = 9.99IQRR7981 pKa = 11.84QFVVDD7986 pKa = 4.78LNNPTADD7993 pKa = 3.45PEE7995 pKa = 4.08IRR7997 pKa = 11.84EE7998 pKa = 4.27TIYY8001 pKa = 10.71EE8002 pKa = 3.85YY8003 pKa = 11.25DD8004 pKa = 3.09EE8005 pKa = 4.8FGRR8008 pKa = 11.84QFRR8011 pKa = 11.84TTDD8014 pKa = 2.97YY8015 pKa = 10.14HH8016 pKa = 7.33GRR8018 pKa = 11.84VSTTTYY8024 pKa = 10.98DD8025 pKa = 3.31DD8026 pKa = 3.23QGRR8029 pKa = 11.84VDD8031 pKa = 3.63TQTSYY8036 pKa = 11.71NGTVTKK8042 pKa = 10.47NYY8044 pKa = 8.26YY8045 pKa = 10.52DD8046 pKa = 3.22NYY8048 pKa = 8.48GRR8050 pKa = 11.84QYY8052 pKa = 9.54KK8053 pKa = 9.64TDD8055 pKa = 3.37VTVGTEE8061 pKa = 3.68TRR8063 pKa = 11.84TTEE8066 pKa = 3.78TVYY8069 pKa = 11.14DD8070 pKa = 4.01SNGNRR8075 pKa = 11.84AQNIDD8080 pKa = 3.49PLGRR8084 pKa = 11.84ITMYY8088 pKa = 10.76AYY8090 pKa = 10.26DD8091 pKa = 3.36QFGRR8095 pKa = 11.84QVSMTQVVGGIDD8107 pKa = 3.59GSAGHH8112 pKa = 6.36EE8113 pKa = 4.3SEE8115 pKa = 4.45TDD8117 pKa = 3.38DD8118 pKa = 5.51LATQTFYY8125 pKa = 11.4DD8126 pKa = 3.24VDD8128 pKa = 3.84GNIDD8132 pKa = 3.55YY8133 pKa = 10.04EE8134 pKa = 4.37INQLGLTRR8142 pKa = 11.84DD8143 pKa = 3.65YY8144 pKa = 11.13EE8145 pKa = 4.21YY8146 pKa = 11.04DD8147 pKa = 3.34AEE8149 pKa = 4.39GRR8151 pKa = 11.84LTGVVLPQVYY8161 pKa = 10.49DD8162 pKa = 3.63PVSQQTISPRR8172 pKa = 11.84YY8173 pKa = 7.76VYY8175 pKa = 10.83VYY8177 pKa = 10.32DD8178 pKa = 3.53DD8179 pKa = 4.7HH8180 pKa = 7.55GNQTEE8185 pKa = 3.9IHH8187 pKa = 7.03EE8188 pKa = 4.53YY8189 pKa = 9.75TSATVFRR8196 pKa = 11.84KK8197 pKa = 7.21TTFTYY8202 pKa = 10.74NDD8204 pKa = 3.08YY8205 pKa = 10.79GQRR8208 pKa = 11.84LTRR8211 pKa = 11.84EE8212 pKa = 4.2LPSGEE8217 pKa = 4.01IEE8219 pKa = 4.32YY8220 pKa = 8.47FTYY8223 pKa = 10.5DD8224 pKa = 3.19VEE8226 pKa = 4.68EE8227 pKa = 4.27YY8228 pKa = 10.67RR8229 pKa = 11.84QDD8231 pKa = 2.96THH8233 pKa = 7.07TDD8235 pKa = 3.64FEE8237 pKa = 5.12GNIVDD8242 pKa = 4.58SVFNADD8248 pKa = 5.08DD8249 pKa = 3.89FLEE8252 pKa = 4.1QMLYY8256 pKa = 7.99FTPGSDD8262 pKa = 3.44PAVDD8266 pKa = 4.29APAEE8270 pKa = 4.27TVTYY8274 pKa = 10.13GYY8276 pKa = 10.78DD8277 pKa = 3.16DD8278 pKa = 4.15YY8279 pKa = 11.84GRR8281 pKa = 11.84KK8282 pKa = 9.17ISMTDD8287 pKa = 2.91NRR8289 pKa = 11.84GTTTYY8294 pKa = 10.67SYY8296 pKa = 11.35DD8297 pKa = 3.34SNGRR8301 pKa = 11.84QNRR8304 pKa = 11.84IEE8306 pKa = 4.11SPEE8309 pKa = 4.18GIINYY8314 pKa = 9.06EE8315 pKa = 3.85FDD8317 pKa = 5.57PITGQKK8323 pKa = 8.51TRR8325 pKa = 11.84TTTEE8329 pKa = 3.89EE8330 pKa = 3.69IGTANITNDD8339 pKa = 2.99FRR8341 pKa = 11.84YY8342 pKa = 8.59TYY8344 pKa = 10.77DD8345 pKa = 2.83DD8346 pKa = 3.23WGRR8349 pKa = 11.84LKK8351 pKa = 9.94TVEE8354 pKa = 3.91VHH8356 pKa = 5.45EE8357 pKa = 4.43QNDD8360 pKa = 3.76VVLVNPEE8367 pKa = 3.87VTTYY8371 pKa = 10.74QYY8373 pKa = 11.85DD8374 pKa = 3.52LVGNLTYY8381 pKa = 10.78TFLTNGTITAYY8392 pKa = 9.98EE8393 pKa = 3.84YY8394 pKa = 11.2DD8395 pKa = 3.42EE8396 pKa = 5.65LYY8398 pKa = 10.94RR8399 pKa = 11.84LDD8401 pKa = 5.61LLTHH8405 pKa = 6.39YY8406 pKa = 10.73YY8407 pKa = 11.22GDD8409 pKa = 3.91GDD8411 pKa = 4.59NINDD8415 pKa = 3.68TDD8417 pKa = 3.46MSDD8420 pKa = 3.35NVKK8423 pKa = 9.48MAEE8426 pKa = 3.58YY8427 pKa = 9.74DD8428 pKa = 3.6YY8429 pKa = 11.07TVRR8432 pKa = 11.84ADD8434 pKa = 3.34GRR8436 pKa = 11.84RR8437 pKa = 11.84TGVTEE8442 pKa = 4.19STWQSDD8448 pKa = 3.59EE8449 pKa = 4.17TLITTDD8455 pKa = 3.13IFSWTYY8461 pKa = 11.57DD8462 pKa = 3.17NLGRR8466 pKa = 11.84MTQEE8470 pKa = 4.21VLDD8473 pKa = 4.16STDD8476 pKa = 3.72DD8477 pKa = 3.82SLDD8480 pKa = 3.28FTATYY8485 pKa = 10.24TFDD8488 pKa = 4.12LLGNRR8493 pKa = 11.84LTKK8496 pKa = 10.81DD8497 pKa = 3.13LDD8499 pKa = 3.67YY8500 pKa = 10.94FADD8503 pKa = 3.67DD8504 pKa = 3.83TRR8506 pKa = 11.84DD8507 pKa = 3.29EE8508 pKa = 4.77VITYY8512 pKa = 7.58TYY8514 pKa = 11.33NSANQLTSEE8523 pKa = 4.32EE8524 pKa = 4.51KK8525 pKa = 10.32VVGTVDD8531 pKa = 2.98VGTAVNDD8538 pKa = 3.22KK8539 pKa = 9.12HH8540 pKa = 5.88TVYY8543 pKa = 10.62SYY8545 pKa = 10.84TGTLRR8550 pKa = 11.84TGKK8553 pKa = 7.92TVYY8556 pKa = 10.72NKK8558 pKa = 9.84VDD8560 pKa = 3.96FEE8562 pKa = 4.61TLSFPDD8568 pKa = 4.16PLEE8571 pKa = 4.35HH8572 pKa = 6.42TTFEE8576 pKa = 4.47YY8577 pKa = 11.0NLQGRR8582 pKa = 11.84MGKK8585 pKa = 8.22VTVDD8589 pKa = 3.49TYY8591 pKa = 10.62TGSSITKK8598 pKa = 9.87QEE8600 pKa = 4.02VTEE8603 pKa = 4.0YY8604 pKa = 10.2EE8605 pKa = 4.16YY8606 pKa = 11.46NEE8608 pKa = 3.84RR8609 pKa = 11.84GIRR8612 pKa = 11.84TEE8614 pKa = 3.54AHH8616 pKa = 5.52HH8617 pKa = 6.58TVDD8620 pKa = 3.74EE8621 pKa = 4.95GNDD8624 pKa = 3.35SVLEE8628 pKa = 3.99VDD8630 pKa = 3.87EE8631 pKa = 4.47TTTYY8635 pKa = 11.39LNDD8638 pKa = 3.83PNNFTGYY8645 pKa = 9.6NQVLEE8650 pKa = 4.24EE8651 pKa = 3.98VTYY8654 pKa = 11.36DD8655 pKa = 3.55NLAEE8659 pKa = 4.16AEE8661 pKa = 4.26KK8662 pKa = 11.07DD8663 pKa = 3.29RR8664 pKa = 11.84AIYY8667 pKa = 8.58TLGMDD8672 pKa = 4.36IISQFRR8678 pKa = 11.84VNSSYY8683 pKa = 10.78PAGFDD8688 pKa = 3.59TVFHH8692 pKa = 6.7YY8693 pKa = 10.61DD8694 pKa = 3.11GHH8696 pKa = 6.73GSTRR8700 pKa = 11.84MLTDD8704 pKa = 2.95MTGALAVYY8712 pKa = 8.3NTVTQLFRR8720 pKa = 11.84YY8721 pKa = 8.94DD8722 pKa = 3.41AYY8724 pKa = 11.01GEE8726 pKa = 3.9AVGFNKK8732 pKa = 10.17SQAATNFLYY8741 pKa = 10.72SGEE8744 pKa = 4.19QFDD8747 pKa = 4.71QRR8749 pKa = 11.84INQQYY8754 pKa = 10.39LRR8756 pKa = 11.84ARR8758 pKa = 11.84YY8759 pKa = 9.09YY8760 pKa = 10.91DD8761 pKa = 3.95LSTGTFNRR8769 pKa = 11.84LDD8771 pKa = 3.58PFFGNLKK8778 pKa = 10.38DD8779 pKa = 3.71PQSLHH8784 pKa = 6.52KK8785 pKa = 10.54YY8786 pKa = 9.65LYY8788 pKa = 8.94THH8790 pKa = 7.51ADD8792 pKa = 3.64PVNGIDD8798 pKa = 3.28PTGRR8802 pKa = 11.84SFGSLVGTALVTGAWGGAIGGVAGGVLAKK8831 pKa = 10.87FNDD8834 pKa = 3.3QSVWKK8839 pKa = 10.26GIGIGAASGFVGGLLLPFSAALGTAGFTAMGVTTGSAAAFGLFAGGIFAGSVSGALDD8896 pKa = 2.83AWLRR8900 pKa = 11.84GEE8902 pKa = 4.29NPVEE8906 pKa = 4.0GAMIGAFTGLIGGAVAKK8923 pKa = 10.59AVGSSLNAIAQRR8935 pKa = 11.84APSLTDD8941 pKa = 4.39DD8942 pKa = 4.67VIQGLKK8948 pKa = 10.22GSEE8951 pKa = 3.93VLVLGRR8957 pKa = 11.84IQDD8960 pKa = 3.81AVEE8963 pKa = 3.86EE8964 pKa = 4.24LADD8967 pKa = 4.02EE8968 pKa = 4.17LRR8970 pKa = 11.84KK8971 pKa = 10.41AGVNAYY8977 pKa = 8.01TVADD8981 pKa = 4.16PARR8984 pKa = 11.84KK8985 pKa = 8.17FAWMKK8990 pKa = 10.82AIEE8993 pKa = 4.79DD8994 pKa = 3.52WAEE8997 pKa = 3.95ANPAWFRR9004 pKa = 11.84NVYY9007 pKa = 10.05RR9008 pKa = 11.84DD9009 pKa = 3.33LANYY9013 pKa = 9.91VSDD9016 pKa = 3.61AGQIIRR9022 pKa = 11.84ANKK9025 pKa = 9.57IIQNTWDD9032 pKa = 3.6WTSSGYY9038 pKa = 6.97TTLEE9042 pKa = 4.1MIEE9045 pKa = 4.0TGIWSSVRR9053 pKa = 11.84RR9054 pKa = 11.84LGLSEE9059 pKa = 5.02KK9060 pKa = 10.63GPEE9063 pKa = 4.1TIVRR9067 pKa = 11.84ILRR9070 pKa = 11.84EE9071 pKa = 3.9RR9072 pKa = 11.84LL9073 pKa = 3.19

Molecular weight:
973.77 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A518CS95|A0A518CS95_9PLAN DUF1080 domain-containing protein OS=Polystyrenella longa OX=2528007 GN=Pla110_38400 PE=4 SV=1
MM1 pKa = 7.38ATRR4 pKa = 11.84TTSKK8 pKa = 7.76TTTKK12 pKa = 10.81SKK14 pKa = 8.25VTKK17 pKa = 9.96SRR19 pKa = 11.84RR20 pKa = 11.84STPAAAKK27 pKa = 8.2STKK30 pKa = 10.29AKK32 pKa = 9.91TSAKK36 pKa = 8.88STAAKK41 pKa = 10.2SGAKK45 pKa = 8.57KK46 pKa = 6.61TTSRR50 pKa = 11.84TTAAKK55 pKa = 8.83STAAKK60 pKa = 8.48STKK63 pKa = 10.43AKK65 pKa = 9.73TGAAKK70 pKa = 8.98STAAKK75 pKa = 10.24KK76 pKa = 7.94PTTSRR81 pKa = 11.84SASTAKK87 pKa = 9.51RR88 pKa = 11.84TTAAKK93 pKa = 8.59STKK96 pKa = 10.43AKK98 pKa = 10.0TSTAKK103 pKa = 8.63PTKK106 pKa = 10.5AKK108 pKa = 6.97TTAAKK113 pKa = 8.71STKK116 pKa = 10.4AKK118 pKa = 9.93TGTAKK123 pKa = 9.91ATTAKK128 pKa = 9.09KK129 pKa = 5.9TTSRR133 pKa = 11.84STTKK137 pKa = 10.63SPAKK141 pKa = 9.15RR142 pKa = 11.84TTAAKK147 pKa = 8.64STKK150 pKa = 8.93TRR152 pKa = 11.84TSAKK156 pKa = 9.25PAAKK160 pKa = 8.83RR161 pKa = 11.84TTTRR165 pKa = 11.84KK166 pKa = 5.87TTTKK170 pKa = 9.81RR171 pKa = 11.84TTTRR175 pKa = 11.84GKK177 pKa = 10.29KK178 pKa = 9.49

Molecular weight:
18.24 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4607

0

4607

1712920

31

9073

371.8

41.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.803 ± 0.035

1.073 ± 0.016

5.822 ± 0.037

7.295 ± 0.039

4.029 ± 0.021

7.105 ± 0.042

2.238 ± 0.017

5.661 ± 0.025

4.503 ± 0.038

10.045 ± 0.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.327 ± 0.018

3.872 ± 0.031

4.911 ± 0.028

4.41 ± 0.031

5.572 ± 0.033

6.712 ± 0.033

5.654 ± 0.042

6.648 ± 0.027

1.475 ± 0.015

2.845 ± 0.021

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski