Amino acid dipepetide frequency for Rotavirus A (strain RVA/SA11-Both/G3P5B[2]) (RV-A) (Simian Agent 11 (strain Both))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.2AlaAla: 4.2 ± 0.655
1.292AlaCys: 1.292 ± 0.309
3.392AlaAsp: 3.392 ± 0.395
2.261AlaGlu: 2.261 ± 0.672
2.584AlaPhe: 2.584 ± 0.564
2.1AlaGly: 2.1 ± 0.669
0.969AlaHis: 0.969 ± 0.296
3.715AlaIle: 3.715 ± 0.697
3.069AlaLys: 3.069 ± 1.208
4.038AlaLeu: 4.038 ± 0.678
1.131AlaMet: 1.131 ± 0.334
4.846AlaAsn: 4.846 ± 0.799
1.777AlaPro: 1.777 ± 0.413
2.1AlaGln: 2.1 ± 0.442
2.261AlaArg: 2.261 ± 0.799
3.554AlaSer: 3.554 ± 0.571
4.361AlaThr: 4.361 ± 1.059
3.877AlaVal: 3.877 ± 0.842
0.162AlaTrp: 0.162 ± 0.145
1.454AlaTyr: 1.454 ± 0.419
0.0AlaXaa: 0.0 ± 0.0
Cys
0.323CysAla: 0.323 ± 0.194
0.485CysCys: 0.485 ± 0.267
0.808CysAsp: 0.808 ± 0.284
0.485CysGlu: 0.485 ± 0.271
0.808CysPhe: 0.808 ± 0.38
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.131CysIle: 1.131 ± 0.359
1.131CysLys: 1.131 ± 0.55
1.292CysLeu: 1.292 ± 0.471
0.646CysMet: 0.646 ± 0.288
1.131CysAsn: 1.131 ± 0.389
0.323CysPro: 0.323 ± 0.218
0.646CysGln: 0.646 ± 0.334
0.646CysArg: 0.646 ± 0.257
0.646CysSer: 0.646 ± 0.356
1.131CysThr: 1.131 ± 0.524
0.323CysVal: 0.323 ± 0.203
0.0CysTrp: 0.0 ± 0.0
0.646CysTyr: 0.646 ± 0.37
0.0CysXaa: 0.0 ± 0.0
Asp
3.715AspAla: 3.715 ± 0.8
0.646AspCys: 0.646 ± 0.286
4.038AspAsp: 4.038 ± 1.023
3.554AspGlu: 3.554 ± 0.676
3.069AspPhe: 3.069 ± 0.662
2.423AspGly: 2.423 ± 0.376
0.485AspHis: 0.485 ± 0.202
5.169AspIle: 5.169 ± 0.944
3.554AspLys: 3.554 ± 0.877
4.523AspLeu: 4.523 ± 0.5
1.777AspMet: 1.777 ± 0.346
3.392AspAsn: 3.392 ± 0.575
2.1AspPro: 2.1 ± 0.447
2.584AspGln: 2.584 ± 0.5
2.1AspArg: 2.1 ± 0.552
4.523AspSer: 4.523 ± 1.033
3.23AspThr: 3.23 ± 0.869
4.684AspVal: 4.684 ± 0.69
0.969AspTrp: 0.969 ± 0.312
3.23AspTyr: 3.23 ± 0.549
0.0AspXaa: 0.0 ± 0.0
Glu
2.584GluAla: 2.584 ± 0.499
0.162GluCys: 0.162 ± 0.157
2.1GluAsp: 2.1 ± 0.473
4.2GluGlu: 4.2 ± 0.704
2.584GluPhe: 2.584 ± 0.726
1.131GluGly: 1.131 ± 0.432
0.969GluHis: 0.969 ± 0.448
4.684GluIle: 4.684 ± 0.914
3.715GluLys: 3.715 ± 1.059
5.815GluLeu: 5.815 ± 1.209
2.423GluMet: 2.423 ± 0.424
4.038GluAsn: 4.038 ± 0.669
1.938GluPro: 1.938 ± 0.664
2.1GluGln: 2.1 ± 0.564
2.907GluArg: 2.907 ± 0.622
3.23GluSer: 3.23 ± 0.718
2.584GluThr: 2.584 ± 0.559
3.23GluVal: 3.23 ± 0.487
0.808GluTrp: 0.808 ± 0.355
3.877GluTyr: 3.877 ± 0.785
0.0GluXaa: 0.0 ± 0.0
Phe
1.777PheAla: 1.777 ± 0.527
0.485PheCys: 0.485 ± 0.237
3.069PheAsp: 3.069 ± 0.533
2.746PheGlu: 2.746 ± 0.479
1.292PhePhe: 1.292 ± 0.465
1.938PheGly: 1.938 ± 0.499
1.292PheHis: 1.292 ± 0.367
4.2PheIle: 4.2 ± 0.717
4.038PheLys: 4.038 ± 0.725
3.392PheLeu: 3.392 ± 0.878
0.485PheMet: 0.485 ± 0.255
3.715PheAsn: 3.715 ± 0.651
1.777PhePro: 1.777 ± 0.668
1.777PheGln: 1.777 ± 0.611
2.1PheArg: 2.1 ± 0.502
3.23PheSer: 3.23 ± 0.674
2.423PheThr: 2.423 ± 0.58
1.615PheVal: 1.615 ± 0.503
0.162PheTrp: 0.162 ± 0.131
1.777PheTyr: 1.777 ± 0.412
0.0PheXaa: 0.0 ± 0.0
Gly
1.131GlyAla: 1.131 ± 0.226
1.131GlyCys: 1.131 ± 0.34
0.969GlyAsp: 0.969 ± 0.392
1.454GlyGlu: 1.454 ± 0.456
0.969GlyPhe: 0.969 ± 0.353
1.615GlyGly: 1.615 ± 0.574
1.131GlyHis: 1.131 ± 0.485
4.361GlyIle: 4.361 ± 0.704
2.584GlyLys: 2.584 ± 0.58
2.907GlyLeu: 2.907 ± 0.552
0.969GlyMet: 0.969 ± 0.387
1.454GlyAsn: 1.454 ± 0.449
1.454GlyPro: 1.454 ± 0.596
1.292GlyGln: 1.292 ± 0.423
1.131GlyArg: 1.131 ± 0.488
3.715GlySer: 3.715 ± 1.022
1.938GlyThr: 1.938 ± 0.651
2.261GlyVal: 2.261 ± 0.483
0.646GlyTrp: 0.646 ± 0.28
1.131GlyTyr: 1.131 ± 0.468
0.0GlyXaa: 0.0 ± 0.0
His
0.969HisAla: 0.969 ± 0.243
0.485HisCys: 0.485 ± 0.47
1.292HisAsp: 1.292 ± 0.336
0.323HisGlu: 0.323 ± 0.262
0.323HisPhe: 0.323 ± 0.19
0.162HisGly: 0.162 ± 0.179
0.646HisHis: 0.646 ± 0.347
0.808HisIle: 0.808 ± 0.508
1.131HisLys: 1.131 ± 0.435
1.777HisLeu: 1.777 ± 0.546
0.485HisMet: 0.485 ± 0.33
0.808HisAsn: 0.808 ± 0.269
0.646HisPro: 0.646 ± 0.334
0.969HisGln: 0.969 ± 0.415
0.0HisArg: 0.0 ± 0.0
1.777HisSer: 1.777 ± 0.394
0.646HisThr: 0.646 ± 0.214
0.969HisVal: 0.969 ± 0.359
0.162HisTrp: 0.162 ± 0.152
1.454HisTyr: 1.454 ± 0.388
0.0HisXaa: 0.0 ± 0.0
Ile
5.492IleAla: 5.492 ± 0.772
0.646IleCys: 0.646 ± 0.409
3.715IleAsp: 3.715 ± 0.927
5.653IleGlu: 5.653 ± 1.042
2.584IlePhe: 2.584 ± 0.758
3.069IleGly: 3.069 ± 0.622
0.646IleHis: 0.646 ± 0.348
5.492IleIle: 5.492 ± 0.516
5.33IleLys: 5.33 ± 1.103
5.976IleLeu: 5.976 ± 1.028
1.454IleMet: 1.454 ± 0.335
7.107IleAsn: 7.107 ± 0.636
4.523IlePro: 4.523 ± 0.665
4.038IleGln: 4.038 ± 0.62
4.361IleArg: 4.361 ± 0.679
6.138IleSer: 6.138 ± 1.014
6.461IleThr: 6.461 ± 0.853
3.554IleVal: 3.554 ± 0.552
0.323IleTrp: 0.323 ± 0.239
4.846IleTyr: 4.846 ± 1.679
0.0IleXaa: 0.0 ± 0.0
Lys
1.777LysAla: 1.777 ± 0.665
1.292LysCys: 1.292 ± 0.327
2.261LysAsp: 2.261 ± 0.651
4.361LysGlu: 4.361 ± 1.037
2.746LysPhe: 2.746 ± 0.991
2.1LysGly: 2.1 ± 0.544
1.292LysHis: 1.292 ± 0.559
4.361LysIle: 4.361 ± 0.967
3.715LysLys: 3.715 ± 0.706
8.238LysLeu: 8.238 ± 1.135
2.746LysMet: 2.746 ± 0.747
3.715LysAsn: 3.715 ± 0.796
2.1LysPro: 2.1 ± 0.581
3.069LysGln: 3.069 ± 0.604
3.069LysArg: 3.069 ± 0.517
4.846LysSer: 4.846 ± 0.869
2.746LysThr: 2.746 ± 0.44
3.877LysVal: 3.877 ± 0.647
1.615LysTrp: 1.615 ± 0.644
3.392LysTyr: 3.392 ± 1.082
0.0LysXaa: 0.0 ± 0.0
Leu
3.877LeuAla: 3.877 ± 0.674
0.969LeuCys: 0.969 ± 0.468
5.815LeuAsp: 5.815 ± 0.59
5.653LeuGlu: 5.653 ± 1.319
4.2LeuPhe: 4.2 ± 0.757
2.261LeuGly: 2.261 ± 0.402
1.938LeuHis: 1.938 ± 0.555
7.43LeuIle: 7.43 ± 0.624
5.492LeuLys: 5.492 ± 0.942
8.399LeuLeu: 8.399 ± 1.079
3.392LeuMet: 3.392 ± 0.698
7.269LeuAsn: 7.269 ± 0.883
4.361LeuPro: 4.361 ± 0.643
3.877LeuGln: 3.877 ± 0.927
5.492LeuArg: 5.492 ± 0.48
8.076LeuSer: 8.076 ± 0.937
7.592LeuThr: 7.592 ± 0.788
3.392LeuVal: 3.392 ± 0.915
0.646LeuTrp: 0.646 ± 0.211
4.846LeuTyr: 4.846 ± 0.717
0.0LeuXaa: 0.0 ± 0.0
Met
1.938MetAla: 1.938 ± 0.49
0.162MetCys: 0.162 ± 0.145
2.907MetAsp: 2.907 ± 0.717
1.292MetGlu: 1.292 ± 0.579
1.292MetPhe: 1.292 ± 0.34
0.969MetGly: 0.969 ± 0.358
0.808MetHis: 0.808 ± 0.282
1.292MetIle: 1.292 ± 0.409
2.1MetLys: 2.1 ± 0.413
3.392MetLeu: 3.392 ± 0.667
0.808MetMet: 0.808 ± 0.354
1.777MetAsn: 1.777 ± 0.49
0.808MetPro: 0.808 ± 0.332
2.1MetGln: 2.1 ± 0.765
1.938MetArg: 1.938 ± 0.459
2.746MetSer: 2.746 ± 0.694
1.454MetThr: 1.454 ± 0.381
0.808MetVal: 0.808 ± 0.318
0.646MetTrp: 0.646 ± 0.251
0.808MetTyr: 0.808 ± 0.321
0.0MetXaa: 0.0 ± 0.0
Asn
3.715AsnAla: 3.715 ± 0.637
0.485AsnCys: 0.485 ± 0.274
4.2AsnAsp: 4.2 ± 0.727
4.361AsnGlu: 4.361 ± 0.582
2.907AsnPhe: 2.907 ± 0.72
2.907AsnGly: 2.907 ± 0.688
1.938AsnHis: 1.938 ± 0.794
3.392AsnIle: 3.392 ± 1.064
3.392AsnLys: 3.392 ± 0.935
6.461AsnLeu: 6.461 ± 0.924
2.584AsnMet: 2.584 ± 0.59
4.846AsnAsn: 4.846 ± 1.242
1.615AsnPro: 1.615 ± 0.573
2.1AsnGln: 2.1 ± 0.569
2.907AsnArg: 2.907 ± 0.414
5.976AsnSer: 5.976 ± 0.925
3.392AsnThr: 3.392 ± 0.634
5.815AsnVal: 5.815 ± 0.745
1.777AsnTrp: 1.777 ± 0.573
5.007AsnTyr: 5.007 ± 0.673
0.0AsnXaa: 0.0 ± 0.0
Pro
1.454ProAla: 1.454 ± 0.502
0.0ProCys: 0.0 ± 0.0
2.1ProAsp: 2.1 ± 0.496
0.646ProGlu: 0.646 ± 0.313
2.1ProPhe: 2.1 ± 0.408
1.777ProGly: 1.777 ± 0.405
0.969ProHis: 0.969 ± 0.391
4.038ProIle: 4.038 ± 0.441
1.615ProLys: 1.615 ± 0.507
2.423ProLeu: 2.423 ± 0.456
0.969ProMet: 0.969 ± 0.43
2.1ProAsn: 2.1 ± 0.827
1.131ProPro: 1.131 ± 0.52
1.615ProGln: 1.615 ± 0.602
1.454ProArg: 1.454 ± 0.376
2.261ProSer: 2.261 ± 0.703
3.069ProThr: 3.069 ± 0.67
2.746ProVal: 2.746 ± 0.69
0.0ProTrp: 0.0 ± 0.0
1.615ProTyr: 1.615 ± 0.462
0.0ProXaa: 0.0 ± 0.0
Gln
1.615GlnAla: 1.615 ± 0.539
0.485GlnCys: 0.485 ± 0.202
2.423GlnAsp: 2.423 ± 0.626
1.615GlnGlu: 1.615 ± 0.44
2.1GlnPhe: 2.1 ± 0.674
0.323GlnGly: 0.323 ± 0.225
0.969GlnHis: 0.969 ± 0.301
4.2GlnIle: 4.2 ± 0.742
2.261GlnLys: 2.261 ± 0.509
5.492GlnLeu: 5.492 ± 1.323
1.454GlnMet: 1.454 ± 0.498
2.423GlnAsn: 2.423 ± 0.617
1.131GlnPro: 1.131 ± 0.278
2.423GlnGln: 2.423 ± 0.762
2.261GlnArg: 2.261 ± 0.723
1.777GlnSer: 1.777 ± 0.395
4.038GlnThr: 4.038 ± 0.764
3.069GlnVal: 3.069 ± 0.904
0.646GlnTrp: 0.646 ± 0.353
2.1GlnTyr: 2.1 ± 0.426
0.0GlnXaa: 0.0 ± 0.0
Arg
1.777ArgAla: 1.777 ± 0.538
0.646ArgCys: 0.646 ± 0.256
3.069ArgAsp: 3.069 ± 0.539
2.907ArgGlu: 2.907 ± 0.686
2.1ArgPhe: 2.1 ± 0.502
1.615ArgGly: 1.615 ± 0.333
0.646ArgHis: 0.646 ± 0.283
3.877ArgIle: 3.877 ± 0.394
2.584ArgLys: 2.584 ± 0.643
5.007ArgLeu: 5.007 ± 1.159
2.1ArgMet: 2.1 ± 0.534
3.715ArgAsn: 3.715 ± 0.975
0.808ArgPro: 0.808 ± 0.406
1.938ArgGln: 1.938 ± 0.612
2.746ArgArg: 2.746 ± 0.482
4.038ArgSer: 4.038 ± 0.538
2.423ArgThr: 2.423 ± 0.547
2.907ArgVal: 2.907 ± 0.619
0.808ArgTrp: 0.808 ± 0.323
1.292ArgTyr: 1.292 ± 0.367
0.0ArgXaa: 0.0 ± 0.0
Ser
3.877SerAla: 3.877 ± 0.886
0.485SerCys: 0.485 ± 0.283
4.523SerAsp: 4.523 ± 0.977
4.523SerGlu: 4.523 ± 0.643
2.907SerPhe: 2.907 ± 0.807
2.584SerGly: 2.584 ± 0.624
0.485SerHis: 0.485 ± 0.193
7.269SerIle: 7.269 ± 1.295
4.684SerLys: 4.684 ± 0.725
7.753SerLeu: 7.753 ± 1.063
2.261SerMet: 2.261 ± 0.541
5.492SerAsn: 5.492 ± 0.99
2.584SerPro: 2.584 ± 0.584
3.392SerGln: 3.392 ± 0.753
3.554SerArg: 3.554 ± 0.667
5.976SerSer: 5.976 ± 1.47
5.33SerThr: 5.33 ± 1.33
5.169SerVal: 5.169 ± 0.945
0.646SerTrp: 0.646 ± 0.306
3.23SerTyr: 3.23 ± 0.959
0.0SerXaa: 0.0 ± 0.0
Thr
4.523ThrAla: 4.523 ± 1.244
0.646ThrCys: 0.646 ± 0.295
4.523ThrAsp: 4.523 ± 0.881
3.23ThrGlu: 3.23 ± 0.649
3.877ThrPhe: 3.877 ± 0.56
2.423ThrGly: 2.423 ± 0.614
0.485ThrHis: 0.485 ± 0.246
5.815ThrIle: 5.815 ± 0.776
3.715ThrLys: 3.715 ± 0.491
7.592ThrLeu: 7.592 ± 1.52
1.615ThrMet: 1.615 ± 0.535
3.392ThrAsn: 3.392 ± 0.394
1.292ThrPro: 1.292 ± 0.338
2.584ThrGln: 2.584 ± 0.726
2.261ThrArg: 2.261 ± 0.59
5.007ThrSer: 5.007 ± 0.618
5.492ThrThr: 5.492 ± 1.13
4.361ThrVal: 4.361 ± 0.61
0.646ThrTrp: 0.646 ± 0.32
2.261ThrTyr: 2.261 ± 0.64
0.0ThrXaa: 0.0 ± 0.0
Val
4.684ValAla: 4.684 ± 0.892
0.969ValCys: 0.969 ± 0.42
5.007ValAsp: 5.007 ± 0.826
3.392ValGlu: 3.392 ± 0.611
2.584ValPhe: 2.584 ± 0.509
2.423ValGly: 2.423 ± 0.465
0.162ValHis: 0.162 ± 0.152
5.169ValIle: 5.169 ± 0.68
3.877ValLys: 3.877 ± 0.742
5.976ValLeu: 5.976 ± 0.684
1.777ValMet: 1.777 ± 0.634
3.554ValAsn: 3.554 ± 0.82
1.777ValPro: 1.777 ± 0.357
1.615ValGln: 1.615 ± 0.469
1.938ValArg: 1.938 ± 0.482
4.038ValSer: 4.038 ± 0.95
3.554ValThr: 3.554 ± 0.86
3.554ValVal: 3.554 ± 0.836
0.0ValTrp: 0.0 ± 0.0
2.746ValTyr: 2.746 ± 0.437
0.0ValXaa: 0.0 ± 0.0
Trp
0.162TrpAla: 0.162 ± 0.131
0.485TrpCys: 0.485 ± 0.47
0.969TrpAsp: 0.969 ± 0.279
0.162TrpGlu: 0.162 ± 0.169
0.162TrpPhe: 0.162 ± 0.167
0.162TrpGly: 0.162 ± 0.145
0.0TrpHis: 0.0 ± 0.0
1.454TrpIle: 1.454 ± 0.495
1.938TrpLys: 1.938 ± 0.455
1.615TrpLeu: 1.615 ± 0.255
0.162TrpMet: 0.162 ± 0.145
0.485TrpAsn: 0.485 ± 0.338
0.485TrpPro: 0.485 ± 0.255
0.646TrpGln: 0.646 ± 0.432
0.485TrpArg: 0.485 ± 0.329
0.485TrpSer: 0.485 ± 0.202
0.485TrpThr: 0.485 ± 0.239
0.162TrpVal: 0.162 ± 0.157
0.323TrpTrp: 0.323 ± 0.218
0.808TrpTyr: 0.808 ± 0.38
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.554TyrAla: 3.554 ± 0.725
0.646TyrCys: 0.646 ± 0.337
2.584TyrAsp: 2.584 ± 0.662
2.261TyrGlu: 2.261 ± 0.46
2.1TyrPhe: 2.1 ± 0.549
2.261TyrGly: 2.261 ± 0.683
0.0TyrHis: 0.0 ± 0.0
3.554TyrIle: 3.554 ± 0.71
3.392TyrLys: 3.392 ± 0.628
2.907TyrLeu: 2.907 ± 1.02
0.646TyrMet: 0.646 ± 0.344
4.523TyrAsn: 4.523 ± 0.795
1.454TyrPro: 1.454 ± 0.321
1.938TyrGln: 1.938 ± 0.531
3.392TyrArg: 3.392 ± 0.736
4.684TyrSer: 4.684 ± 1.462
3.392TyrThr: 3.392 ± 0.866
2.584TyrVal: 2.584 ± 0.389
0.646TyrTrp: 0.646 ± 0.309
3.23TyrTyr: 3.23 ± 1.067
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (6192 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski