Amino acid dipepetide frequency for Hubei rhabdo-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.046AlaAla: 1.046 ± 0.335
1.394AlaCys: 1.394 ± 0.765
1.046AlaAsp: 1.046 ± 0.924
2.091AlaGlu: 2.091 ± 1.147
1.046AlaPhe: 1.046 ± 0.335
0.697AlaGly: 0.697 ± 0.402
1.046AlaHis: 1.046 ± 0.335
3.137AlaIle: 3.137 ± 1.526
4.531AlaLys: 4.531 ± 0.895
2.091AlaLeu: 2.091 ± 0.832
0.697AlaMet: 0.697 ± 0.382
2.091AlaAsn: 2.091 ± 0.832
1.046AlaPro: 1.046 ± 0.335
1.743AlaGln: 1.743 ± 0.956
2.091AlaArg: 2.091 ± 1.384
2.788AlaSer: 2.788 ± 2.112
2.788AlaThr: 2.788 ± 1.096
0.697AlaVal: 0.697 ± 0.382
0.0AlaTrp: 0.0 ± 0.0
1.394AlaTyr: 1.394 ± 0.624
0.0AlaXaa: 0.0 ± 0.0
Cys
0.349CysAla: 0.349 ± 0.191
0.697CysCys: 0.697 ± 0.382
1.394CysAsp: 1.394 ± 0.624
2.788CysGlu: 2.788 ± 0.738
1.394CysPhe: 1.394 ± 0.369
1.743CysGly: 1.743 ± 0.715
1.046CysHis: 1.046 ± 0.574
1.046CysIle: 1.046 ± 0.335
1.743CysLys: 1.743 ± 0.956
2.091CysLeu: 2.091 ± 0.635
0.0CysMet: 0.0 ± 0.0
0.349CysAsn: 0.349 ± 0.191
0.697CysPro: 0.697 ± 0.382
0.349CysGln: 0.349 ± 0.191
1.394CysArg: 1.394 ± 0.765
2.788CysSer: 2.788 ± 1.608
0.697CysThr: 0.697 ± 0.382
0.697CysVal: 0.697 ± 1.066
0.349CysTrp: 0.349 ± 0.838
1.046CysTyr: 1.046 ± 0.335
0.0CysXaa: 0.0 ± 0.0
Asp
1.394AspAla: 1.394 ± 0.624
1.046AspCys: 1.046 ± 1.599
4.183AspAsp: 4.183 ± 1.873
3.137AspGlu: 3.137 ± 1.419
3.834AspPhe: 3.834 ± 1.672
2.091AspGly: 2.091 ± 1.206
1.046AspHis: 1.046 ± 0.335
3.486AspIle: 3.486 ± 1.917
5.577AspLys: 5.577 ± 0.717
6.623AspLeu: 6.623 ± 1.992
1.046AspMet: 1.046 ± 0.574
3.486AspAsn: 3.486 ± 1.347
1.046AspPro: 1.046 ± 0.335
2.788AspGln: 2.788 ± 1.12
1.046AspArg: 1.046 ± 0.924
1.046AspSer: 1.046 ± 0.574
4.183AspThr: 4.183 ± 1.107
2.788AspVal: 2.788 ± 0.738
0.0AspTrp: 0.0 ± 0.0
4.88AspTyr: 4.88 ± 2.096
0.0AspXaa: 0.0 ± 0.0
Glu
1.394GluAla: 1.394 ± 1.123
2.091GluCys: 2.091 ± 0.67
3.486GluAsp: 3.486 ± 2.878
4.531GluGlu: 4.531 ± 4.351
3.486GluPhe: 3.486 ± 1.481
4.183GluGly: 4.183 ± 1.34
1.394GluHis: 1.394 ± 0.691
6.274GluIle: 6.274 ± 4.233
8.365GluLys: 8.365 ± 3.359
8.714GluLeu: 8.714 ± 2.764
1.046GluMet: 1.046 ± 0.574
3.486GluAsn: 3.486 ± 1.004
2.788GluPro: 2.788 ± 0.359
2.091GluGln: 2.091 ± 1.384
2.091GluArg: 2.091 ± 1.313
3.486GluSer: 3.486 ± 1.037
3.486GluThr: 3.486 ± 1.037
2.788GluVal: 2.788 ± 0.431
1.046GluTrp: 1.046 ± 0.692
2.44GluTyr: 2.44 ± 0.804
0.0GluXaa: 0.0 ± 0.0
Phe
0.697PheAla: 0.697 ± 0.744
1.046PheCys: 1.046 ± 0.574
3.486PheAsp: 3.486 ± 0.722
4.183PheGlu: 4.183 ± 1.753
5.228PhePhe: 5.228 ± 0.767
3.137PheGly: 3.137 ± 0.836
0.697PheHis: 0.697 ± 1.066
2.788PheIle: 2.788 ± 1.042
3.486PheLys: 3.486 ± 1.347
5.925PheLeu: 5.925 ± 4.251
0.697PheMet: 0.697 ± 0.506
4.183PheAsn: 4.183 ± 1.72
0.697PhePro: 0.697 ± 0.744
2.44PheGln: 2.44 ± 0.804
2.091PheArg: 2.091 ± 0.635
2.091PheSer: 2.091 ± 0.741
2.091PheThr: 2.091 ± 1.147
2.788PheVal: 2.788 ± 0.738
0.349PheTrp: 0.349 ± 0.191
2.091PheTyr: 2.091 ± 0.635
0.0PheXaa: 0.0 ± 0.0
Gly
1.394GlyAla: 1.394 ± 0.804
1.046GlyCys: 1.046 ± 0.574
1.743GlyAsp: 1.743 ± 0.715
3.834GlyGlu: 3.834 ± 1.791
5.228GlyPhe: 5.228 ± 0.69
3.137GlyGly: 3.137 ± 1.005
1.743GlyHis: 1.743 ± 0.715
3.137GlyIle: 3.137 ± 0.836
3.834GlyLys: 3.834 ± 0.216
4.531GlyLeu: 4.531 ± 1.436
1.394GlyMet: 1.394 ± 0.804
2.788GlyAsn: 2.788 ± 1.608
1.743GlyPro: 1.743 ± 0.741
1.046GlyGln: 1.046 ± 0.574
2.788GlyArg: 2.788 ± 1.701
3.834GlySer: 3.834 ± 0.216
2.091GlyThr: 2.091 ± 0.67
2.44GlyVal: 2.44 ± 1.879
0.0GlyTrp: 0.0 ± 0.0
2.091GlyTyr: 2.091 ± 1.849
0.0GlyXaa: 0.0 ± 0.0
His
0.697HisAla: 0.697 ± 0.382
0.349HisCys: 0.349 ± 0.191
1.394HisAsp: 1.394 ± 0.765
0.697HisGlu: 0.697 ± 1.066
0.349HisPhe: 0.349 ± 0.191
0.349HisGly: 0.349 ± 0.533
1.046HisHis: 1.046 ± 0.574
2.788HisIle: 2.788 ± 0.359
2.44HisLys: 2.44 ± 0.804
3.137HisLeu: 3.137 ± 1.163
0.697HisMet: 0.697 ± 0.382
1.394HisAsn: 1.394 ± 0.765
1.394HisPro: 1.394 ± 0.369
1.046HisGln: 1.046 ± 0.574
1.394HisArg: 1.394 ± 0.369
2.788HisSer: 2.788 ± 1.12
0.697HisThr: 0.697 ± 0.402
1.046HisVal: 1.046 ± 0.335
0.349HisTrp: 0.349 ± 0.191
1.046HisTyr: 1.046 ± 0.574
0.0HisXaa: 0.0 ± 0.0
Ile
1.743IleAla: 1.743 ± 0.956
1.743IleCys: 1.743 ± 1.322
4.531IleAsp: 4.531 ± 2.092
5.228IleGlu: 5.228 ± 0.69
3.834IlePhe: 3.834 ± 2.103
3.486IleGly: 3.486 ± 0.663
2.44IleHis: 2.44 ± 1.338
6.274IleIle: 6.274 ± 0.733
8.365IleLys: 8.365 ± 0.362
6.623IleLeu: 6.623 ± 1.95
1.394IleMet: 1.394 ± 0.624
4.88IleAsn: 4.88 ± 0.364
2.788IlePro: 2.788 ± 0.431
3.486IleGln: 3.486 ± 0.965
3.137IleArg: 3.137 ± 1.163
6.971IleSer: 6.971 ± 3.273
3.486IleThr: 3.486 ± 0.722
5.925IleVal: 5.925 ± 2.536
1.046IleTrp: 1.046 ± 0.335
3.486IleTyr: 3.486 ± 2.047
0.0IleXaa: 0.0 ± 0.0
Lys
2.091LysAla: 2.091 ± 0.741
1.394LysCys: 1.394 ± 0.765
4.183LysAsp: 4.183 ± 1.72
7.32LysGlu: 7.32 ± 1.068
3.137LysPhe: 3.137 ± 2.054
3.486LysGly: 3.486 ± 0.03
2.091LysHis: 2.091 ± 0.635
6.274LysIle: 6.274 ± 2.124
3.834LysLys: 3.834 ± 0.839
10.108LysLeu: 10.108 ± 1.311
1.743LysMet: 1.743 ± 0.483
5.925LysAsn: 5.925 ± 2.664
2.44LysPro: 2.44 ± 0.678
3.486LysGln: 3.486 ± 1.43
3.834LysArg: 3.834 ± 1.533
3.834LysSer: 3.834 ± 1.112
5.577LysThr: 5.577 ± 2.268
3.834LysVal: 3.834 ± 0.839
1.046LysTrp: 1.046 ± 0.574
3.834LysTyr: 3.834 ± 1.672
0.0LysXaa: 0.0 ± 0.0
Leu
6.971LeuAla: 6.971 ± 2.095
3.137LeuCys: 3.137 ± 1.251
6.623LeuAsp: 6.623 ± 2.031
3.486LeuGlu: 3.486 ± 0.722
4.88LeuPhe: 4.88 ± 2.156
6.623LeuGly: 6.623 ± 1.181
2.44LeuHis: 2.44 ± 1.338
6.971LeuIle: 6.971 ± 2.239
8.714LeuLys: 8.714 ± 1.411
11.502LeuLeu: 11.502 ± 3.253
1.394LeuMet: 1.394 ± 0.369
4.88LeuAsn: 4.88 ± 1.721
3.137LeuPro: 3.137 ± 1.062
2.44LeuGln: 2.44 ± 0.804
2.788LeuArg: 2.788 ± 1.12
9.411LeuSer: 9.411 ± 3.154
6.623LeuThr: 6.623 ± 1.181
3.834LeuVal: 3.834 ± 1.533
0.349LeuTrp: 0.349 ± 0.191
6.274LeuTyr: 6.274 ± 0.733
0.0LeuXaa: 0.0 ± 0.0
Met
1.046MetAla: 1.046 ± 0.335
0.0MetCys: 0.0 ± 0.0
1.046MetAsp: 1.046 ± 0.574
1.743MetGlu: 1.743 ± 0.956
1.046MetPhe: 1.046 ± 0.574
0.697MetGly: 0.697 ± 0.382
0.349MetHis: 0.349 ± 0.191
2.091MetIle: 2.091 ± 0.635
1.743MetLys: 1.743 ± 0.483
0.697MetLeu: 0.697 ± 0.382
0.349MetMet: 0.349 ± 0.191
0.0MetAsn: 0.0 ± 0.0
0.697MetPro: 0.697 ± 1.066
0.349MetGln: 0.349 ± 0.191
1.046MetArg: 1.046 ± 0.574
2.091MetSer: 2.091 ± 0.832
1.743MetThr: 1.743 ± 0.483
1.046MetVal: 1.046 ± 0.692
0.349MetTrp: 0.349 ± 0.191
0.349MetTyr: 0.349 ± 0.533
0.0MetXaa: 0.0 ± 0.0
Asn
3.137AsnAla: 3.137 ± 1.005
1.046AsnCys: 1.046 ± 0.79
1.394AsnAsp: 1.394 ± 0.765
2.788AsnGlu: 2.788 ± 0.981
1.394AsnPhe: 1.394 ± 0.369
2.44AsnGly: 2.44 ± 0.55
1.743AsnHis: 1.743 ± 0.956
6.274AsnIle: 6.274 ± 0.459
3.834AsnLys: 3.834 ± 0.894
5.925AsnLeu: 5.925 ± 1.745
0.0AsnMet: 0.0 ± 0.0
3.486AsnAsn: 3.486 ± 0.965
3.486AsnPro: 3.486 ± 0.722
1.046AsnGln: 1.046 ± 0.574
1.743AsnArg: 1.743 ± 0.715
5.577AsnSer: 5.577 ± 1.172
2.788AsnThr: 2.788 ± 1.042
3.137AsnVal: 3.137 ± 0.836
1.394AsnTrp: 1.394 ± 0.369
4.88AsnTyr: 4.88 ± 1.608
0.0AsnXaa: 0.0 ± 0.0
Pro
0.697ProAla: 0.697 ± 0.382
0.0ProCys: 0.0 ± 0.0
1.394ProAsp: 1.394 ± 0.765
3.486ProGlu: 3.486 ± 2.878
1.394ProPhe: 1.394 ± 0.765
2.44ProGly: 2.44 ± 1.879
1.046ProHis: 1.046 ± 0.692
2.788ProIle: 2.788 ± 1.015
3.834ProLys: 3.834 ± 1.127
2.091ProLeu: 2.091 ± 0.376
0.697ProMet: 0.697 ± 0.382
2.44ProAsn: 2.44 ± 0.804
1.743ProPro: 1.743 ± 0.956
1.394ProGln: 1.394 ± 0.369
1.394ProArg: 1.394 ± 0.804
3.486ProSer: 3.486 ± 1.31
2.44ProThr: 2.44 ± 0.55
2.091ProVal: 2.091 ± 0.741
0.349ProTrp: 0.349 ± 0.191
1.046ProTyr: 1.046 ± 0.574
0.0ProXaa: 0.0 ± 0.0
Gln
1.046GlnAla: 1.046 ± 0.574
0.697GlnCys: 0.697 ± 0.402
2.788GlnAsp: 2.788 ± 0.738
1.743GlnGlu: 1.743 ± 0.956
0.697GlnPhe: 0.697 ± 0.382
1.743GlnGly: 1.743 ± 0.741
0.697GlnHis: 0.697 ± 0.402
4.183GlnIle: 4.183 ± 1.481
3.486GlnLys: 3.486 ± 0.722
5.228GlnLeu: 5.228 ± 1.626
0.0GlnMet: 0.0 ± 0.0
2.091GlnAsn: 2.091 ± 0.832
0.349GlnPro: 0.349 ± 0.533
2.788GlnGln: 2.788 ± 0.981
2.091GlnArg: 2.091 ± 1.313
2.788GlnSer: 2.788 ± 0.981
1.394GlnThr: 1.394 ± 0.369
2.788GlnVal: 2.788 ± 0.981
0.0GlnTrp: 0.0 ± 0.0
1.394GlnTyr: 1.394 ± 0.369
0.0GlnXaa: 0.0 ± 0.0
Arg
1.394ArgAla: 1.394 ± 0.369
0.349ArgCys: 0.349 ± 0.191
1.394ArgAsp: 1.394 ± 0.369
3.834ArgGlu: 3.834 ± 3.708
2.091ArgPhe: 2.091 ± 0.635
2.788ArgGly: 2.788 ± 0.359
1.046ArgHis: 1.046 ± 0.335
2.44ArgIle: 2.44 ± 0.804
4.183ArgLys: 4.183 ± 0.752
3.834ArgLeu: 3.834 ± 1.039
2.091ArgMet: 2.091 ± 1.147
1.743ArgAsn: 1.743 ± 1.322
0.349ArgPro: 0.349 ± 0.191
2.091ArgGln: 2.091 ± 0.376
1.743ArgArg: 1.743 ± 0.956
3.137ArgSer: 3.137 ± 1.005
2.091ArgThr: 2.091 ± 1.384
2.091ArgVal: 2.091 ± 0.635
0.349ArgTrp: 0.349 ± 0.191
3.137ArgTyr: 3.137 ± 0.836
0.0ArgXaa: 0.0 ± 0.0
Ser
2.44SerAla: 2.44 ± 1.205
3.137SerCys: 3.137 ± 0.838
3.486SerAsp: 3.486 ± 0.722
5.925SerGlu: 5.925 ± 0.984
2.788SerPhe: 2.788 ± 1.248
3.137SerGly: 3.137 ± 2.123
2.091SerHis: 2.091 ± 1.147
5.577SerIle: 5.577 ± 0.647
3.834SerLys: 3.834 ± 1.112
8.365SerLeu: 8.365 ± 0.747
1.046SerMet: 1.046 ± 0.71
2.788SerAsn: 2.788 ± 1.015
4.531SerPro: 4.531 ± 3.257
3.486SerGln: 3.486 ± 1.037
3.834SerArg: 3.834 ± 0.503
4.88SerSer: 4.88 ± 0.364
4.183SerThr: 4.183 ± 3.583
3.834SerVal: 3.834 ± 0.216
0.0SerTrp: 0.0 ± 0.0
3.137SerTyr: 3.137 ± 0.836
0.0SerXaa: 0.0 ± 0.0
Thr
2.091ThrAla: 2.091 ± 0.832
1.046ThrCys: 1.046 ± 0.924
2.788ThrAsp: 2.788 ± 0.359
4.531ThrGlu: 4.531 ± 2.673
1.394ThrPhe: 1.394 ± 0.369
2.44ThrGly: 2.44 ± 0.55
0.697ThrHis: 0.697 ± 1.066
5.228ThrIle: 5.228 ± 0.767
2.44ThrLys: 2.44 ± 0.55
6.274ThrLeu: 6.274 ± 2.502
2.091ThrMet: 2.091 ± 0.588
2.788ThrAsn: 2.788 ± 0.431
3.486ThrPro: 3.486 ± 0.957
2.44ThrGln: 2.44 ± 0.804
1.743ThrArg: 1.743 ± 0.483
3.834ThrSer: 3.834 ± 0.839
2.44ThrThr: 2.44 ± 0.356
4.183ThrVal: 4.183 ± 1.036
1.046ThrTrp: 1.046 ± 0.335
3.137ThrTyr: 3.137 ± 0.838
0.0ThrXaa: 0.0 ± 0.0
Val
1.743ValAla: 1.743 ± 0.483
1.046ValCys: 1.046 ± 0.574
3.137ValAsp: 3.137 ± 0.563
3.486ValGlu: 3.486 ± 1.355
3.137ValPhe: 3.137 ± 1.526
2.788ValGly: 2.788 ± 0.359
1.046ValHis: 1.046 ± 0.79
3.834ValIle: 3.834 ± 1.373
2.788ValLys: 2.788 ± 0.359
1.743ValLeu: 1.743 ± 0.478
1.046ValMet: 1.046 ± 0.574
5.228ValAsn: 5.228 ± 1.783
2.091ValPro: 2.091 ± 1.313
0.697ValGln: 0.697 ± 0.402
2.788ValArg: 2.788 ± 1.608
4.183ValSer: 4.183 ± 1.073
3.137ValThr: 3.137 ± 2.123
2.788ValVal: 2.788 ± 1.608
0.349ValTrp: 0.349 ± 0.533
3.486ValTyr: 3.486 ± 1.037
0.0ValXaa: 0.0 ± 0.0
Trp
0.349TrpAla: 0.349 ± 0.191
0.0TrpCys: 0.0 ± 0.0
0.697TrpAsp: 0.697 ± 0.382
0.349TrpGlu: 0.349 ± 0.533
0.0TrpPhe: 0.0 ± 0.0
0.349TrpGly: 0.349 ± 0.191
0.0TrpHis: 0.0 ± 0.0
0.697TrpIle: 0.697 ± 0.402
0.697TrpLys: 0.697 ± 0.382
0.697TrpLeu: 0.697 ± 0.382
0.349TrpMet: 0.349 ± 0.191
0.349TrpAsn: 0.349 ± 0.191
0.0TrpPro: 0.0 ± 0.0
0.349TrpGln: 0.349 ± 0.838
0.349TrpArg: 0.349 ± 0.838
1.046TrpSer: 1.046 ± 0.924
1.046TrpThr: 1.046 ± 0.574
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.394TrpTyr: 1.394 ± 0.369
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.743TyrAla: 1.743 ± 0.741
1.394TyrCys: 1.394 ± 0.369
4.531TyrAsp: 4.531 ± 1.335
3.486TyrGlu: 3.486 ± 2.488
3.834TyrPhe: 3.834 ± 0.216
2.091TyrGly: 2.091 ± 0.67
1.394TyrHis: 1.394 ± 0.765
5.577TyrIle: 5.577 ± 2.475
1.743TyrLys: 1.743 ± 0.956
6.274TyrLeu: 6.274 ± 1.716
0.349TyrMet: 0.349 ± 0.191
3.137TyrAsn: 3.137 ± 2.123
1.743TyrPro: 1.743 ± 0.478
2.44TyrGln: 2.44 ± 0.678
2.788TyrArg: 2.788 ± 1.042
2.788TyrSer: 2.788 ± 0.359
3.137TyrThr: 3.137 ± 1.062
1.743TyrVal: 1.743 ± 0.478
0.349TyrTrp: 0.349 ± 0.533
1.743TyrTyr: 1.743 ± 0.483
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2870 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski