Cyprinid herpesvirus 2

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Alloherpesviridae; Cyprinivirus

Average proteome isoelectric point is 6.22

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 150 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|K7PC21|K7PC21_9VIRU Protein ORF156 OS=Cyprinid herpesvirus 2 OX=317878 GN=CyHV2_ORF156 PE=4 SV=1
MM1 pKa = 7.39ARR3 pKa = 11.84CDD5 pKa = 5.18FFKK8 pKa = 10.61QWLLSSLPFILCIIGEE24 pKa = 4.3YY25 pKa = 10.53LVVGALAVAIIISSGIMVKK44 pKa = 10.55DD45 pKa = 3.86IDD47 pKa = 4.05DD48 pKa = 3.64QQATGEE54 pKa = 4.25CWPAVLLSGSGLFLTRR70 pKa = 11.84FWTVHH75 pKa = 5.38NYY77 pKa = 8.9QFGRR81 pKa = 11.84TRR83 pKa = 11.84TILGTRR89 pKa = 11.84SRR91 pKa = 11.84RR92 pKa = 11.84MRR94 pKa = 11.84FAAVILAIFVVASGVMSIWASIGDD118 pKa = 3.63MVMTYY123 pKa = 10.08MNDD126 pKa = 3.23HH127 pKa = 7.11ANPKK131 pKa = 8.23PTLDD135 pKa = 3.75QLEE138 pKa = 4.24QQEE141 pKa = 4.49KK142 pKa = 10.59DD143 pKa = 3.78VPCLFRR149 pKa = 11.84CYY151 pKa = 10.43GGYY154 pKa = 8.06HH155 pKa = 5.63TSIVLYY161 pKa = 10.19TMLAAGFCLLAIGLEE176 pKa = 4.22MEE178 pKa = 4.8DD179 pKa = 3.28RR180 pKa = 11.84AVDD183 pKa = 3.63AEE185 pKa = 4.13EE186 pKa = 4.5DD187 pKa = 3.66ALIGSTASAFTPDD200 pKa = 3.15STVDD204 pKa = 3.41LTAIPPPLPPPYY216 pKa = 10.14NGDD219 pKa = 3.58GVPPPSYY226 pKa = 10.72TNIINIYY233 pKa = 8.33TGNNGSGSEE242 pKa = 4.34APPPSYY248 pKa = 10.29EE249 pKa = 4.01VAVGEE254 pKa = 4.31TSQPEE259 pKa = 4.34EE260 pKa = 4.06PQQDD264 pKa = 3.47SSEE267 pKa = 4.12PQPDD271 pKa = 3.27SSEE274 pKa = 4.15PQPEE278 pKa = 3.83TRR280 pKa = 11.84IIITMM285 pKa = 4.39

Molecular weight: 31.02 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|K7PBQ8|K7PBQ8_9VIRU ORF2A OS=Cyprinid herpesvirus 2 OX=317878 GN=CyHV2_149 PE=4 SV=1
MM1 pKa = 7.4VYY3 pKa = 10.67YY4 pKa = 10.08ILLLGLVGLGLGEE17 pKa = 4.3STNTSSSNSSSIASSLPPPKK37 pKa = 8.85ITHH40 pKa = 6.47IPTTTSPTVTVTVTDD55 pKa = 3.98LMLGLVVLLLVVILSLLVVILLTLKK80 pKa = 10.64RR81 pKa = 11.84MRR83 pKa = 11.84KK84 pKa = 8.85DD85 pKa = 3.09AKK87 pKa = 10.71AEE89 pKa = 3.82KK90 pKa = 10.08DD91 pKa = 3.52KK92 pKa = 11.15KK93 pKa = 10.55QKK95 pKa = 10.29PDD97 pKa = 3.69DD98 pKa = 3.86VEE100 pKa = 4.05MSLLRR105 pKa = 11.84RR106 pKa = 11.84MHH108 pKa = 6.77SDD110 pKa = 2.72HH111 pKa = 5.86MHH113 pKa = 5.21MHH115 pKa = 6.32SEE117 pKa = 3.82AAGPFGNMYY126 pKa = 8.94TRR128 pKa = 11.84PLPSPPQNQWWQNGTLGGRR147 pKa = 11.84SASMSDD153 pKa = 3.47LDD155 pKa = 4.96EE156 pKa = 4.26PTQRR160 pKa = 11.84EE161 pKa = 4.21NSWRR165 pKa = 11.84RR166 pKa = 11.84QRR168 pKa = 11.84HH169 pKa = 4.34GPITAAMRR177 pKa = 11.84GSGRR181 pKa = 11.84GRR183 pKa = 11.84GRR185 pKa = 11.84GQGPRR190 pKa = 11.84MGYY193 pKa = 9.83RR194 pKa = 11.84PGGVGGNEE202 pKa = 3.72NGGGVFYY209 pKa = 11.17SLGHH213 pKa = 4.82VV214 pKa = 3.47

Molecular weight: 23.21 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

150

0

150

78638

62

4113

524.3

58.56

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.735 ± 0.161

2.208 ± 0.102

6.062 ± 0.165

6.023 ± 0.21

3.559 ± 0.096

5.13 ± 0.168

2.173 ± 0.109

4.144 ± 0.088

5.366 ± 0.204

8.636 ± 0.17

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.809 ± 0.092

4.106 ± 0.159

5.42 ± 0.174

3.942 ± 0.174

5.605 ± 0.143

8.113 ± 0.185

7.405 ± 0.37

7.035 ± 0.113

1.283 ± 0.074

3.245 ± 0.098
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski