Streptococcus merionis

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus

Average proteome isoelectric point is 6.11

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2137 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A239SLY0|A0A239SLY0_9STRE Uncharacterized protein OS=Streptococcus merionis OX=400065 GN=SAMEA4412692_00232 PE=4 SV=1
MM1 pKa = 7.62ALAKK5 pKa = 9.78IVYY8 pKa = 10.47ASMTGNTEE16 pKa = 3.87EE17 pKa = 4.51IADD20 pKa = 3.59IVSNKK25 pKa = 10.11LEE27 pKa = 3.97EE28 pKa = 4.66LGVDD32 pKa = 3.7VEE34 pKa = 4.72TNEE37 pKa = 4.38CTTVDD42 pKa = 4.19ADD44 pKa = 4.69DD45 pKa = 5.58FLDD48 pKa = 4.26ADD50 pKa = 4.23LVIVATYY57 pKa = 9.31TYY59 pKa = 11.24GDD61 pKa = 3.83GEE63 pKa = 4.56LPDD66 pKa = 4.96EE67 pKa = 4.49IVDD70 pKa = 4.45FYY72 pKa = 11.79EE73 pKa = 6.45DD74 pKa = 4.72LLQLDD79 pKa = 4.97LSGKK83 pKa = 9.94IYY85 pKa = 10.01GVCGSGDD92 pKa = 3.21TFYY95 pKa = 11.45DD96 pKa = 4.02EE97 pKa = 4.52FCKK100 pKa = 10.94SVDD103 pKa = 3.45EE104 pKa = 4.33FDD106 pKa = 4.5AAFTSTGATKK116 pKa = 10.23GAEE119 pKa = 4.2SVKK122 pKa = 10.33VDD124 pKa = 4.94LAAEE128 pKa = 4.52DD129 pKa = 4.61DD130 pKa = 4.8DD131 pKa = 5.89IINLEE136 pKa = 4.49DD137 pKa = 3.56FAQALAEE144 pKa = 4.15HH145 pKa = 6.32VLL147 pKa = 3.64

Molecular weight:
15.88 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A239SVE3|A0A239SVE3_9STRE LacI family transcriptional repressor OS=Streptococcus merionis OX=400065 GN=malR PE=4 SV=1
MM1 pKa = 7.45KK2 pKa = 9.59RR3 pKa = 11.84TFQPSKK9 pKa = 9.26IRR11 pKa = 11.84RR12 pKa = 11.84ARR14 pKa = 11.84KK15 pKa = 8.35HH16 pKa = 4.78GFRR19 pKa = 11.84NRR21 pKa = 11.84MSTKK25 pKa = 9.22NGRR28 pKa = 11.84RR29 pKa = 11.84VLAARR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84KK37 pKa = 8.78GRR39 pKa = 11.84KK40 pKa = 8.62VLAVSS45 pKa = 3.94

Molecular weight:
5.36 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2137

0

2137

660612

29

2271

309.1

34.57

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.921 ± 0.063

0.577 ± 0.015

5.646 ± 0.049

6.796 ± 0.061

4.531 ± 0.043

6.584 ± 0.049

1.909 ± 0.023

7.224 ± 0.053

6.237 ± 0.06

10.328 ± 0.078

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.547 ± 0.027

4.221 ± 0.038

3.459 ± 0.029

4.211 ± 0.046

4.084 ± 0.039

6.12 ± 0.038

5.908 ± 0.054

7.035 ± 0.043

0.917 ± 0.019

3.741 ± 0.034

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski