Amino acid dipepetide frequency for Facklamia languida CCUG 37842

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.368AlaAla: 5.368 ± 0.144
0.592AlaCys: 0.592 ± 0.038
4.469AlaAsp: 4.469 ± 0.109
4.629AlaGlu: 4.629 ± 0.133
3.322AlaPhe: 3.322 ± 0.084
5.479AlaGly: 5.479 ± 0.119
1.453AlaHis: 1.453 ± 0.059
6.414AlaIle: 6.414 ± 0.117
4.514AlaLys: 4.514 ± 0.111
8.222AlaLeu: 8.222 ± 0.142
2.231AlaMet: 2.231 ± 0.067
3.182AlaAsn: 3.182 ± 0.085
2.326AlaPro: 2.326 ± 0.085
3.838AlaGln: 3.838 ± 0.104
3.024AlaArg: 3.024 ± 0.087
5.003AlaSer: 5.003 ± 0.112
3.848AlaThr: 3.848 ± 0.084
4.902AlaVal: 4.902 ± 0.116
0.682AlaTrp: 0.682 ± 0.04
3.102AlaTyr: 3.102 ± 0.084
0.0AlaXaa: 0.0 ± 0.0
Cys
0.343CysAla: 0.343 ± 0.03
0.074CysCys: 0.074 ± 0.013
0.36CysAsp: 0.36 ± 0.025
0.329CysGlu: 0.329 ± 0.027
0.296CysPhe: 0.296 ± 0.028
0.538CysGly: 0.538 ± 0.035
0.205CysHis: 0.205 ± 0.022
0.364CysIle: 0.364 ± 0.027
0.166CysLys: 0.166 ± 0.021
0.814CysLeu: 0.814 ± 0.045
0.086CysMet: 0.086 ± 0.013
0.171CysAsn: 0.171 ± 0.019
0.294CysPro: 0.294 ± 0.025
0.477CysGln: 0.477 ± 0.033
0.3CysArg: 0.3 ± 0.027
0.318CysSer: 0.318 ± 0.027
0.224CysThr: 0.224 ± 0.025
0.302CysVal: 0.302 ± 0.024
0.055CysTrp: 0.055 ± 0.012
0.277CysTyr: 0.277 ± 0.024
0.0CysXaa: 0.0 ± 0.0
Asp
3.413AspAla: 3.413 ± 0.097
0.364AspCys: 0.364 ± 0.028
2.661AspAsp: 2.661 ± 0.09
3.928AspGlu: 3.928 ± 0.11
2.79AspPhe: 2.79 ± 0.074
3.314AspGly: 3.314 ± 0.075
2.2AspHis: 2.2 ± 0.087
3.32AspIle: 3.32 ± 0.084
3.129AspLys: 3.129 ± 0.101
7.852AspLeu: 7.852 ± 0.147
1.224AspMet: 1.224 ± 0.054
1.837AspAsn: 1.837 ± 0.062
3.133AspPro: 3.133 ± 0.083
6.205AspGln: 6.205 ± 0.144
3.365AspArg: 3.365 ± 0.09
2.985AspSer: 2.985 ± 0.09
2.309AspThr: 2.309 ± 0.072
3.061AspVal: 3.061 ± 0.088
0.799AspTrp: 0.799 ± 0.047
3.324AspTyr: 3.324 ± 0.083
0.0AspXaa: 0.0 ± 0.0
Glu
6.572GluAla: 6.572 ± 0.149
0.312GluCys: 0.312 ± 0.026
4.896GluAsp: 4.896 ± 0.116
6.944GluGlu: 6.944 ± 0.232
2.268GluPhe: 2.268 ± 0.068
4.417GluGly: 4.417 ± 0.106
0.914GluHis: 0.914 ± 0.044
4.939GluIle: 4.939 ± 0.107
3.552GluLys: 3.552 ± 0.111
5.831GluLeu: 5.831 ± 0.138
2.209GluMet: 2.209 ± 0.066
2.622GluAsn: 2.622 ± 0.088
2.1GluPro: 2.1 ± 0.077
2.445GluGln: 2.445 ± 0.086
3.18GluArg: 3.18 ± 0.088
3.628GluSer: 3.628 ± 0.088
3.873GluThr: 3.873 ± 0.133
5.329GluVal: 5.329 ± 0.141
0.723GluTrp: 0.723 ± 0.036
1.966GluTyr: 1.966 ± 0.069
0.0GluXaa: 0.0 ± 0.0
Phe
2.889PheAla: 2.889 ± 0.085
0.281PheCys: 0.281 ± 0.026
2.858PheAsp: 2.858 ± 0.076
2.601PheGlu: 2.601 ± 0.083
1.808PhePhe: 1.808 ± 0.074
2.675PheGly: 2.675 ± 0.083
0.74PheHis: 0.74 ± 0.041
3.246PheIle: 3.246 ± 0.099
2.389PheLys: 2.389 ± 0.077
3.961PheLeu: 3.961 ± 0.115
1.151PheMet: 1.151 ± 0.05
2.073PheAsn: 2.073 ± 0.069
1.436PhePro: 1.436 ± 0.057
1.703PheGln: 1.703 ± 0.06
1.313PheArg: 1.313 ± 0.055
2.597PheSer: 2.597 ± 0.083
2.369PheThr: 2.369 ± 0.079
2.638PheVal: 2.638 ± 0.083
0.417PheTrp: 0.417 ± 0.029
1.746PheTyr: 1.746 ± 0.068
0.0PheXaa: 0.0 ± 0.0
Gly
4.253GlyAla: 4.253 ± 0.104
0.485GlyCys: 0.485 ± 0.038
3.468GlyAsp: 3.468 ± 0.084
3.963GlyGlu: 3.963 ± 0.135
2.864GlyPhe: 2.864 ± 0.078
4.051GlyGly: 4.051 ± 0.116
1.629GlyHis: 1.629 ± 0.053
4.941GlyIle: 4.941 ± 0.098
3.694GlyLys: 3.694 ± 0.101
7.094GlyLeu: 7.094 ± 0.16
1.804GlyMet: 1.804 ± 0.062
2.204GlyAsn: 2.204 ± 0.068
1.991GlyPro: 1.991 ± 0.065
4.101GlyGln: 4.101 ± 0.101
2.809GlyArg: 2.809 ± 0.084
3.881GlySer: 3.881 ± 0.102
3.353GlyThr: 3.353 ± 0.099
4.58GlyVal: 4.58 ± 0.099
0.606GlyTrp: 0.606 ± 0.039
2.728GlyTyr: 2.728 ± 0.083
0.0GlyXaa: 0.0 ± 0.0
His
1.352HisAla: 1.352 ± 0.054
0.131HisCys: 0.131 ± 0.014
1.218HisAsp: 1.218 ± 0.053
1.185HisGlu: 1.185 ± 0.051
1.224HisPhe: 1.224 ± 0.061
1.171HisGly: 1.171 ± 0.05
0.906HisHis: 0.906 ± 0.053
1.222HisIle: 1.222 ± 0.045
0.904HisLys: 0.904 ± 0.047
2.656HisLeu: 2.656 ± 0.082
0.419HisMet: 0.419 ± 0.03
0.655HisAsn: 0.655 ± 0.033
1.319HisPro: 1.319 ± 0.049
1.728HisGln: 1.728 ± 0.065
0.988HisArg: 0.988 ± 0.048
1.165HisSer: 1.165 ± 0.05
0.988HisThr: 0.988 ± 0.046
1.188HisVal: 1.188 ± 0.052
0.228HisTrp: 0.228 ± 0.024
1.327HisTyr: 1.327 ± 0.064
0.0HisXaa: 0.0 ± 0.0
Ile
5.761IleAla: 5.761 ± 0.119
0.59IleCys: 0.59 ± 0.034
4.865IleAsp: 4.865 ± 0.105
5.091IleGlu: 5.091 ± 0.107
2.804IlePhe: 2.804 ± 0.098
4.9IleGly: 4.9 ± 0.103
1.654IleHis: 1.654 ± 0.061
5.064IleIle: 5.064 ± 0.126
3.934IleLys: 3.934 ± 0.104
7.296IleLeu: 7.296 ± 0.163
1.637IleMet: 1.637 ± 0.058
3.059IleAsn: 3.059 ± 0.073
3.002IlePro: 3.002 ± 0.088
3.856IleGln: 3.856 ± 0.106
3.164IleArg: 3.164 ± 0.081
3.959IleSer: 3.959 ± 0.105
3.661IleThr: 3.661 ± 0.106
4.653IleVal: 4.653 ± 0.102
0.553IleTrp: 0.553 ± 0.034
2.607IleTyr: 2.607 ± 0.072
0.0IleXaa: 0.0 ± 0.0
Lys
4.327LysAla: 4.327 ± 0.12
0.216LysCys: 0.216 ± 0.023
3.908LysAsp: 3.908 ± 0.098
5.138LysGlu: 5.138 ± 0.127
1.551LysPhe: 1.551 ± 0.059
3.55LysGly: 3.55 ± 0.09
0.902LysHis: 0.902 ± 0.046
3.645LysIle: 3.645 ± 0.081
3.427LysLys: 3.427 ± 0.099
4.319LysLeu: 4.319 ± 0.108
1.467LysMet: 1.467 ± 0.046
2.233LysAsn: 2.233 ± 0.07
1.937LysPro: 1.937 ± 0.066
2.757LysGln: 2.757 ± 0.08
2.533LysArg: 2.533 ± 0.072
2.772LysSer: 2.772 ± 0.073
2.827LysThr: 2.827 ± 0.09
4.101LysVal: 4.101 ± 0.114
0.52LysTrp: 0.52 ± 0.037
1.777LysTyr: 1.777 ± 0.06
0.0LysXaa: 0.0 ± 0.0
Leu
9.438LeuAla: 9.438 ± 0.145
0.563LeuCys: 0.563 ± 0.035
6.657LeuAsp: 6.657 ± 0.14
6.517LeuGlu: 6.517 ± 0.128
4.039LeuPhe: 4.039 ± 0.112
6.293LeuGly: 6.293 ± 0.132
1.65LeuHis: 1.65 ± 0.059
7.801LeuIle: 7.801 ± 0.158
5.929LeuLys: 5.929 ± 0.121
10.281LeuLeu: 10.281 ± 0.215
2.848LeuMet: 2.848 ± 0.093
4.649LeuAsn: 4.649 ± 0.103
4.243LeuPro: 4.243 ± 0.1
4.078LeuGln: 4.078 ± 0.118
3.906LeuArg: 3.906 ± 0.088
7.119LeuSer: 7.119 ± 0.136
6.145LeuThr: 6.145 ± 0.117
7.209LeuVal: 7.209 ± 0.159
0.746LeuTrp: 0.746 ± 0.043
3.31LeuTyr: 3.31 ± 0.084
0.0LeuXaa: 0.0 ± 0.0
Met
2.354MetAla: 2.354 ± 0.072
0.129MetCys: 0.129 ± 0.016
1.598MetAsp: 1.598 ± 0.054
1.549MetGlu: 1.549 ± 0.055
0.684MetPhe: 0.684 ± 0.041
1.695MetGly: 1.695 ± 0.058
0.38MetHis: 0.38 ± 0.025
2.087MetIle: 2.087 ± 0.072
1.8MetLys: 1.8 ± 0.062
1.96MetLeu: 1.96 ± 0.069
0.861MetMet: 0.861 ± 0.046
1.346MetAsn: 1.346 ± 0.053
0.931MetPro: 0.931 ± 0.046
1.068MetGln: 1.068 ± 0.041
1.116MetArg: 1.116 ± 0.05
1.469MetSer: 1.469 ± 0.056
1.925MetThr: 1.925 ± 0.066
2.057MetVal: 2.057 ± 0.082
0.138MetTrp: 0.138 ± 0.018
0.579MetTyr: 0.579 ± 0.04
0.0MetXaa: 0.0 ± 0.0
Asn
2.49AsnAla: 2.49 ± 0.077
0.234AsnCys: 0.234 ± 0.019
2.065AsnAsp: 2.065 ± 0.062
2.515AsnGlu: 2.515 ± 0.078
1.732AsnPhe: 1.732 ± 0.059
2.57AsnGly: 2.57 ± 0.078
1.142AsnHis: 1.142 ± 0.04
2.543AsnIle: 2.543 ± 0.083
2.219AsnLys: 2.219 ± 0.07
4.021AsnLeu: 4.021 ± 0.09
0.914AsnMet: 0.914 ± 0.044
1.426AsnAsn: 1.426 ± 0.058
2.155AsnPro: 2.155 ± 0.071
3.447AsnGln: 3.447 ± 0.091
2.231AsnArg: 2.231 ± 0.067
1.814AsnSer: 1.814 ± 0.063
1.588AsnThr: 1.588 ± 0.063
2.248AsnVal: 2.248 ± 0.073
0.39AsnTrp: 0.39 ± 0.029
1.759AsnTyr: 1.759 ± 0.065
0.0AsnXaa: 0.0 ± 0.0
Pro
2.995ProAla: 2.995 ± 0.097
0.177ProCys: 0.177 ± 0.02
2.601ProAsp: 2.601 ± 0.077
3.008ProGlu: 3.008 ± 0.083
1.802ProPhe: 1.802 ± 0.076
2.546ProGly: 2.546 ± 0.081
0.935ProHis: 0.935 ± 0.049
2.907ProIle: 2.907 ± 0.097
1.886ProLys: 1.886 ± 0.069
3.756ProLeu: 3.756 ± 0.089
0.927ProMet: 0.927 ± 0.041
1.627ProAsn: 1.627 ± 0.059
0.906ProPro: 0.906 ± 0.047
2.001ProGln: 2.001 ± 0.07
1.218ProArg: 1.218 ± 0.052
2.56ProSer: 2.56 ± 0.08
2.118ProThr: 2.118 ± 0.076
2.839ProVal: 2.839 ± 0.093
0.331ProTrp: 0.331 ± 0.027
1.555ProTyr: 1.555 ± 0.061
0.0ProXaa: 0.0 ± 0.0
Gln
6.829GlnAla: 6.829 ± 0.19
0.203GlnCys: 0.203 ± 0.024
3.487GlnAsp: 3.487 ± 0.082
4.857GlnGlu: 4.857 ± 0.125
1.783GlnPhe: 1.783 ± 0.061
3.602GlnGly: 3.602 ± 0.112
0.849GlnHis: 0.849 ± 0.038
3.743GlnIle: 3.743 ± 0.103
2.622GlnLys: 2.622 ± 0.073
5.611GlnLeu: 5.611 ± 0.131
1.473GlnMet: 1.473 ± 0.056
1.728GlnAsn: 1.728 ± 0.061
2.118GlnPro: 2.118 ± 0.081
2.453GlnGln: 2.453 ± 0.096
2.332GlnArg: 2.332 ± 0.072
3.098GlnSer: 3.098 ± 0.088
3.059GlnThr: 3.059 ± 0.082
5.085GlnVal: 5.085 ± 0.123
0.553GlnTrp: 0.553 ± 0.035
1.5GlnTyr: 1.5 ± 0.053
0.0GlnXaa: 0.0 ± 0.0
Arg
2.617ArgAla: 2.617 ± 0.08
0.224ArgCys: 0.224 ± 0.022
2.32ArgAsp: 2.32 ± 0.069
2.784ArgGlu: 2.784 ± 0.079
1.755ArgPhe: 1.755 ± 0.058
2.285ArgGly: 2.285 ± 0.076
1.138ArgHis: 1.138 ± 0.052
3.197ArgIle: 3.197 ± 0.079
2.441ArgLys: 2.441 ± 0.078
4.898ArgLeu: 4.898 ± 0.102
1.188ArgMet: 1.188 ± 0.055
1.57ArgAsn: 1.57 ± 0.061
1.687ArgPro: 1.687 ± 0.056
3.148ArgGln: 3.148 ± 0.09
2.219ArgArg: 2.219 ± 0.076
2.511ArgSer: 2.511 ± 0.075
2.052ArgThr: 2.052 ± 0.063
2.868ArgVal: 2.868 ± 0.083
0.405ArgTrp: 0.405 ± 0.031
1.896ArgTyr: 1.896 ± 0.069
0.0ArgXaa: 0.0 ± 0.0
Ser
3.704SerAla: 3.704 ± 0.098
0.294SerCys: 0.294 ± 0.028
3.439SerAsp: 3.439 ± 0.079
3.408SerGlu: 3.408 ± 0.094
2.741SerPhe: 2.741 ± 0.08
4.056SerGly: 4.056 ± 0.11
1.422SerHis: 1.422 ± 0.058
4.308SerIle: 4.308 ± 0.095
3.16SerLys: 3.16 ± 0.091
6.696SerLeu: 6.696 ± 0.149
1.442SerMet: 1.442 ± 0.061
2.229SerAsn: 2.229 ± 0.085
2.334SerPro: 2.334 ± 0.079
4.144SerGln: 4.144 ± 0.105
2.426SerArg: 2.426 ± 0.081
3.503SerSer: 3.503 ± 0.095
2.835SerThr: 2.835 ± 0.087
3.408SerVal: 3.408 ± 0.085
0.487SerTrp: 0.487 ± 0.032
2.194SerTyr: 2.194 ± 0.067
0.0SerXaa: 0.0 ± 0.0
Thr
3.622ThrAla: 3.622 ± 0.084
0.366ThrCys: 0.366 ± 0.028
2.95ThrAsp: 2.95 ± 0.082
2.757ThrGlu: 2.757 ± 0.112
2.33ThrPhe: 2.33 ± 0.072
3.932ThrGly: 3.932 ± 0.094
1.241ThrHis: 1.241 ± 0.048
4.259ThrIle: 4.259 ± 0.106
2.566ThrLys: 2.566 ± 0.107
5.695ThrLeu: 5.695 ± 0.101
1.167ThrMet: 1.167 ± 0.05
2.102ThrAsn: 2.102 ± 0.076
2.361ThrPro: 2.361 ± 0.074
2.33ThrGln: 2.33 ± 0.069
2.081ThrArg: 2.081 ± 0.063
3.316ThrSer: 3.316 ± 0.096
3.38ThrThr: 3.38 ± 0.171
3.702ThrVal: 3.702 ± 0.094
0.512ThrTrp: 0.512 ± 0.033
2.264ThrTyr: 2.264 ± 0.073
0.0ThrXaa: 0.0 ± 0.0
Val
5.202ValAla: 5.202 ± 0.117
0.397ValCys: 0.397 ± 0.03
4.52ValAsp: 4.52 ± 0.102
4.853ValGlu: 4.853 ± 0.117
2.821ValPhe: 2.821 ± 0.084
4.467ValGly: 4.467 ± 0.117
1.257ValHis: 1.257 ± 0.049
5.247ValIle: 5.247 ± 0.105
3.762ValLys: 3.762 ± 0.093
6.583ValLeu: 6.583 ± 0.147
1.711ValMet: 1.711 ± 0.066
3.016ValAsn: 3.016 ± 0.074
2.391ValPro: 2.391 ± 0.066
2.936ValGln: 2.936 ± 0.076
2.554ValArg: 2.554 ± 0.07
4.043ValSer: 4.043 ± 0.096
4.037ValThr: 4.037 ± 0.108
5.003ValVal: 5.003 ± 0.124
0.581ValTrp: 0.581 ± 0.035
2.441ValTyr: 2.441 ± 0.078
0.0ValXaa: 0.0 ± 0.0
Trp
0.559TrpAla: 0.559 ± 0.037
0.062TrpCys: 0.062 ± 0.012
0.47TrpAsp: 0.47 ± 0.032
0.481TrpGlu: 0.481 ± 0.034
0.39TrpPhe: 0.39 ± 0.031
0.551TrpGly: 0.551 ± 0.037
0.234TrpHis: 0.234 ± 0.021
0.651TrpIle: 0.651 ± 0.041
0.394TrpLys: 0.394 ± 0.028
1.222TrpLeu: 1.222 ± 0.052
0.318TrpMet: 0.318 ± 0.026
0.39TrpAsn: 0.39 ± 0.035
0.308TrpPro: 0.308 ± 0.027
0.777TrpGln: 0.777 ± 0.04
0.417TrpArg: 0.417 ± 0.029
0.495TrpSer: 0.495 ± 0.03
0.462TrpThr: 0.462 ± 0.03
0.612TrpVal: 0.612 ± 0.031
0.111TrpTrp: 0.111 ± 0.015
0.3TrpTyr: 0.3 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.511TyrAla: 2.511 ± 0.081
0.3TyrCys: 0.3 ± 0.027
2.406TyrAsp: 2.406 ± 0.069
2.184TyrGlu: 2.184 ± 0.08
1.886TyrPhe: 1.886 ± 0.065
2.408TyrGly: 2.408 ± 0.075
1.126TyrHis: 1.126 ± 0.055
2.211TyrIle: 2.211 ± 0.068
1.418TyrLys: 1.418 ± 0.059
4.653TyrLeu: 4.653 ± 0.092
0.647TyrMet: 0.647 ± 0.037
1.385TyrAsn: 1.385 ± 0.052
1.724TyrPro: 1.724 ± 0.063
3.493TyrGln: 3.493 ± 0.101
2.024TyrArg: 2.024 ± 0.077
1.997TyrSer: 1.997 ± 0.064
1.878TyrThr: 1.878 ± 0.076
2.036TyrVal: 2.036 ± 0.062
0.37TyrTrp: 0.37 ± 0.031
1.711TyrTyr: 1.711 ± 0.067
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1527 proteins (486735 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski