Amino acid dipepetide frequency for Chicken anemia virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.822AlaAla: 3.822 ± 1.715
0.0AlaCys: 0.0 ± 0.0
6.369AlaAsp: 6.369 ± 1.404
0.0AlaGlu: 0.0 ± 0.0
3.822AlaPhe: 3.822 ± 2.097
7.643AlaGly: 7.643 ± 0.712
0.0AlaHis: 0.0 ± 0.0
1.274AlaIle: 1.274 ± 1.123
3.822AlaLys: 3.822 ± 1.715
6.369AlaLeu: 6.369 ± 0.549
1.274AlaMet: 1.274 ± 0.699
2.548AlaAsn: 2.548 ± 1.16
3.822AlaPro: 3.822 ± 1.273
6.369AlaGln: 6.369 ± 1.974
7.643AlaArg: 7.643 ± 2.444
5.096AlaSer: 5.096 ± 1.332
10.191AlaThr: 10.191 ± 2.377
3.822AlaVal: 3.822 ± 1.715
3.822AlaTrp: 3.822 ± 2.097
1.274AlaTyr: 1.274 ± 0.699
0.0AlaXaa: 0.0 ± 0.0
Cys
2.548CysAla: 2.548 ± 1.935
0.0CysCys: 0.0 ± 0.0
1.274CysAsp: 1.274 ± 1.475
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.548CysGly: 2.548 ± 1.935
0.0CysHis: 0.0 ± 0.0
1.274CysIle: 1.274 ± 1.475
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.274CysMet: 1.274 ± 0.699
1.274CysAsn: 1.274 ± 1.123
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.548CysArg: 2.548 ± 1.16
1.274CysSer: 1.274 ± 1.123
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.274CysTrp: 1.274 ± 0.699
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.274AspAla: 1.274 ± 0.699
0.0AspCys: 0.0 ± 0.0
1.274AspAsp: 1.274 ± 0.699
5.096AspGlu: 5.096 ± 2.819
2.548AspPhe: 2.548 ± 2.245
2.548AspGly: 2.548 ± 0.674
2.548AspHis: 2.548 ± 1.398
2.548AspIle: 2.548 ± 2.245
0.0AspLys: 0.0 ± 0.0
1.274AspLeu: 1.274 ± 1.475
1.274AspMet: 1.274 ± 0.699
2.548AspAsn: 2.548 ± 1.16
5.096AspPro: 5.096 ± 0.687
1.274AspGln: 1.274 ± 1.475
2.548AspArg: 2.548 ± 2.245
3.822AspSer: 3.822 ± 0.791
3.822AspThr: 3.822 ± 1.222
2.548AspVal: 2.548 ± 1.398
1.274AspTrp: 1.274 ± 1.123
1.274AspTyr: 1.274 ± 1.123
0.0AspXaa: 0.0 ± 0.0
Glu
2.548GluAla: 2.548 ± 2.245
2.548GluCys: 2.548 ± 2.245
5.096GluAsp: 5.096 ± 3.8
2.548GluGlu: 2.548 ± 2.245
1.274GluPhe: 1.274 ± 0.699
3.822GluGly: 3.822 ± 0.791
0.0GluHis: 0.0 ± 0.0
1.274GluIle: 1.274 ± 1.475
0.0GluLys: 0.0 ± 0.0
6.369GluLeu: 6.369 ± 1.404
0.0GluMet: 0.0 ± 0.0
1.274GluAsn: 1.274 ± 1.475
1.274GluPro: 1.274 ± 0.699
2.548GluGln: 2.548 ± 1.398
1.274GluArg: 1.274 ± 1.123
2.548GluSer: 2.548 ± 1.935
3.822GluThr: 3.822 ± 1.222
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.548GluTyr: 2.548 ± 1.16
0.0GluXaa: 0.0 ± 0.0
Phe
1.274PheAla: 1.274 ± 0.699
0.0PheCys: 0.0 ± 0.0
2.548PheAsp: 2.548 ± 2.245
0.0PheGlu: 0.0 ± 0.0
2.548PhePhe: 2.548 ± 1.398
2.548PheGly: 2.548 ± 1.398
1.274PheHis: 1.274 ± 0.699
0.0PheIle: 0.0 ± 0.0
1.274PheLys: 1.274 ± 1.475
2.548PheLeu: 2.548 ± 1.398
0.0PheMet: 0.0 ± 0.0
2.548PheAsn: 2.548 ± 1.398
1.274PhePro: 1.274 ± 0.699
3.822PheGln: 3.822 ± 0.791
7.643PheArg: 7.643 ± 1.052
1.274PheSer: 1.274 ± 0.699
5.096PheThr: 5.096 ± 2.819
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.274PheTyr: 1.274 ± 0.699
0.0PheXaa: 0.0 ± 0.0
Gly
5.096GlyAla: 5.096 ± 1.332
1.274GlyCys: 1.274 ± 1.475
2.548GlyAsp: 2.548 ± 0.674
3.822GlyGlu: 3.822 ± 2.097
1.274GlyPhe: 1.274 ± 1.475
10.191GlyGly: 10.191 ± 2.696
0.0GlyHis: 0.0 ± 0.0
6.369GlyIle: 6.369 ± 2.162
2.548GlyLys: 2.548 ± 0.674
2.548GlyLeu: 2.548 ± 0.674
0.0GlyMet: 0.0 ± 0.0
3.822GlyAsn: 3.822 ± 1.715
3.822GlyPro: 3.822 ± 1.273
7.643GlyGln: 7.643 ± 3.43
5.096GlyArg: 5.096 ± 1.332
3.822GlySer: 3.822 ± 0.791
8.917GlyThr: 8.917 ± 3.328
1.274GlyVal: 1.274 ± 1.123
1.274GlyTrp: 1.274 ± 0.699
1.274GlyTyr: 1.274 ± 0.699
0.0GlyXaa: 0.0 ± 0.0
His
1.274HisAla: 1.274 ± 1.123
1.274HisCys: 1.274 ± 1.475
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.274HisGly: 1.274 ± 1.123
2.548HisHis: 2.548 ± 1.398
1.274HisIle: 1.274 ± 0.699
1.274HisLys: 1.274 ± 0.699
3.822HisLeu: 3.822 ± 2.097
0.0HisMet: 0.0 ± 0.0
1.274HisAsn: 1.274 ± 0.699
1.274HisPro: 1.274 ± 0.699
1.274HisGln: 1.274 ± 0.699
1.274HisArg: 1.274 ± 0.699
1.274HisSer: 1.274 ± 1.123
1.274HisThr: 1.274 ± 0.699
0.0HisVal: 0.0 ± 0.0
1.274HisTrp: 1.274 ± 1.123
1.274HisTyr: 1.274 ± 1.123
0.0HisXaa: 0.0 ± 0.0
Ile
6.369IleAla: 6.369 ± 0.549
1.274IleCys: 1.274 ± 1.123
0.0IleAsp: 0.0 ± 0.0
1.274IleGlu: 1.274 ± 0.699
1.274IlePhe: 1.274 ± 0.699
3.822IleGly: 3.822 ± 1.273
0.0IleHis: 0.0 ± 0.0
2.548IleIle: 2.548 ± 1.398
0.0IleLys: 0.0 ± 0.0
2.548IleLeu: 2.548 ± 0.674
0.0IleMet: 0.0 ± 0.0
2.548IleAsn: 2.548 ± 2.245
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
3.822IleArg: 3.822 ± 2.561
2.548IleSer: 2.548 ± 0.674
6.369IleThr: 6.369 ± 3.692
2.548IleVal: 2.548 ± 2.245
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.548LysAla: 2.548 ± 1.398
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
3.822LysGlu: 3.822 ± 1.222
3.822LysPhe: 3.822 ± 0.791
2.548LysGly: 2.548 ± 1.398
1.274LysHis: 1.274 ± 1.123
3.822LysIle: 3.822 ± 0.791
2.548LysLys: 2.548 ± 1.935
1.274LysLeu: 1.274 ± 1.123
1.274LysMet: 1.274 ± 0.699
3.822LysAsn: 3.822 ± 1.222
1.274LysPro: 1.274 ± 1.475
1.274LysGln: 1.274 ± 0.699
5.096LysArg: 5.096 ± 2.101
2.548LysSer: 2.548 ± 1.398
1.274LysThr: 1.274 ± 1.123
1.274LysVal: 1.274 ± 1.123
0.0LysTrp: 0.0 ± 0.0
1.274LysTyr: 1.274 ± 0.699
0.0LysXaa: 0.0 ± 0.0
Leu
3.822LeuAla: 3.822 ± 0.791
1.274LeuCys: 1.274 ± 1.475
3.822LeuAsp: 3.822 ± 0.791
3.822LeuGlu: 3.822 ± 2.799
1.274LeuPhe: 1.274 ± 0.699
5.096LeuGly: 5.096 ± 1.332
0.0LeuHis: 0.0 ± 0.0
3.822LeuIle: 3.822 ± 1.222
5.096LeuLys: 5.096 ± 1.618
5.096LeuLeu: 5.096 ± 1.332
1.274LeuMet: 1.274 ± 1.075
0.0LeuAsn: 0.0 ± 0.0
3.822LeuPro: 3.822 ± 2.097
3.822LeuGln: 3.822 ± 1.273
7.643LeuArg: 7.643 ± 3.983
3.822LeuSer: 3.822 ± 1.273
5.096LeuThr: 5.096 ± 2.796
1.274LeuVal: 1.274 ± 0.699
0.0LeuTrp: 0.0 ± 0.0
2.548LeuTyr: 2.548 ± 1.398
0.0LeuXaa: 0.0 ± 0.0
Met
1.274MetAla: 1.274 ± 0.699
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.274MetPhe: 1.274 ± 0.699
1.274MetGly: 1.274 ± 0.699
1.274MetHis: 1.274 ± 1.123
0.0MetIle: 0.0 ± 0.0
1.274MetLys: 1.274 ± 0.699
0.0MetLeu: 0.0 ± 0.0
2.548MetMet: 2.548 ± 1.398
3.822MetAsn: 3.822 ± 1.222
1.274MetPro: 1.274 ± 0.699
1.274MetGln: 1.274 ± 0.699
1.274MetArg: 1.274 ± 0.699
1.274MetSer: 1.274 ± 0.699
5.096MetThr: 5.096 ± 2.796
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.274MetTyr: 1.274 ± 0.699
0.0MetXaa: 0.0 ± 0.0
Asn
2.548AsnAla: 2.548 ± 2.951
2.548AsnCys: 2.548 ± 0.674
0.0AsnAsp: 0.0 ± 0.0
2.548AsnGlu: 2.548 ± 0.674
2.548AsnPhe: 2.548 ± 0.674
2.548AsnGly: 2.548 ± 2.245
3.822AsnHis: 3.822 ± 0.791
0.0AsnIle: 0.0 ± 0.0
2.548AsnLys: 2.548 ± 0.674
2.548AsnLeu: 2.548 ± 1.398
0.0AsnMet: 0.0 ± 0.0
1.274AsnAsn: 1.274 ± 0.699
3.822AsnPro: 3.822 ± 0.791
0.0AsnGln: 0.0 ± 0.0
3.822AsnArg: 3.822 ± 0.791
5.096AsnSer: 5.096 ± 1.618
1.274AsnThr: 1.274 ± 1.475
2.548AsnVal: 2.548 ± 1.16
2.548AsnTrp: 2.548 ± 1.398
1.274AsnTyr: 1.274 ± 1.123
0.0AsnXaa: 0.0 ± 0.0
Pro
5.096ProAla: 5.096 ± 1.348
0.0ProCys: 0.0 ± 0.0
5.096ProAsp: 5.096 ± 0.687
0.0ProGlu: 0.0 ± 0.0
1.274ProPhe: 1.274 ± 1.123
5.096ProGly: 5.096 ± 0.687
1.274ProHis: 1.274 ± 1.475
2.548ProIle: 2.548 ± 1.398
5.096ProLys: 5.096 ± 1.618
5.096ProLeu: 5.096 ± 0.687
2.548ProMet: 2.548 ± 1.253
3.822ProAsn: 3.822 ± 0.791
7.643ProPro: 7.643 ± 3.481
1.274ProGln: 1.274 ± 0.699
5.096ProArg: 5.096 ± 0.687
11.465ProSer: 11.465 ± 5.788
5.096ProThr: 5.096 ± 2.672
3.822ProVal: 3.822 ± 0.791
1.274ProTrp: 1.274 ± 0.699
1.274ProTyr: 1.274 ± 0.699
0.0ProXaa: 0.0 ± 0.0
Gln
5.096GlnAla: 5.096 ± 1.348
0.0GlnCys: 0.0 ± 0.0
2.548GlnAsp: 2.548 ± 0.674
2.548GlnGlu: 2.548 ± 1.935
1.274GlnPhe: 1.274 ± 1.123
7.643GlnGly: 7.643 ± 1.582
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.548GlnLeu: 2.548 ± 1.398
1.274GlnMet: 1.274 ± 0.699
2.548GlnAsn: 2.548 ± 1.398
8.917GlnPro: 8.917 ± 1.798
2.548GlnGln: 2.548 ± 1.398
6.369GlnArg: 6.369 ± 1.974
3.822GlnSer: 3.822 ± 2.097
0.0GlnThr: 0.0 ± 0.0
2.548GlnVal: 2.548 ± 0.674
1.274GlnTrp: 1.274 ± 0.699
2.548GlnTyr: 2.548 ± 1.398
0.0GlnXaa: 0.0 ± 0.0
Arg
5.096ArgAla: 5.096 ± 0.687
2.548ArgCys: 2.548 ± 1.16
2.548ArgAsp: 2.548 ± 0.674
5.096ArgGlu: 5.096 ± 3.8
5.096ArgPhe: 5.096 ± 2.796
3.822ArgGly: 3.822 ± 2.097
2.548ArgHis: 2.548 ± 1.398
2.548ArgIle: 2.548 ± 1.935
6.369ArgLys: 6.369 ± 2.352
3.822ArgLeu: 3.822 ± 1.222
1.274ArgMet: 1.274 ± 0.699
0.0ArgAsn: 0.0 ± 0.0
11.465ArgPro: 11.465 ± 2.848
2.548ArgGln: 2.548 ± 1.398
16.561ArgArg: 16.561 ± 5.84
8.917ArgSer: 8.917 ± 3.288
3.822ArgThr: 3.822 ± 3.253
5.096ArgVal: 5.096 ± 0.687
7.643ArgTrp: 7.643 ± 1.582
3.822ArgTyr: 3.822 ± 0.791
0.0ArgXaa: 0.0 ± 0.0
Ser
5.096SerAla: 5.096 ± 0.687
2.548SerCys: 2.548 ± 1.16
3.822SerAsp: 3.822 ± 0.791
7.643SerGlu: 7.643 ± 4.519
5.096SerPhe: 5.096 ± 2.796
2.548SerGly: 2.548 ± 2.245
1.274SerHis: 1.274 ± 1.123
1.274SerIle: 1.274 ± 1.123
2.548SerLys: 2.548 ± 1.16
6.369SerLeu: 6.369 ± 3.2
1.274SerMet: 1.274 ± 0.699
1.274SerAsn: 1.274 ± 1.123
2.548SerPro: 2.548 ± 0.674
6.369SerGln: 6.369 ± 1.974
6.369SerArg: 6.369 ± 3.2
3.822SerSer: 3.822 ± 1.273
8.917SerThr: 8.917 ± 0.135
5.096SerVal: 5.096 ± 2.796
1.274SerTrp: 1.274 ± 0.699
1.274SerTyr: 1.274 ± 0.699
0.0SerXaa: 0.0 ± 0.0
Thr
11.465ThrAla: 11.465 ± 2.139
0.0ThrCys: 0.0 ± 0.0
3.822ThrAsp: 3.822 ± 1.222
2.548ThrGlu: 2.548 ± 1.398
0.0ThrPhe: 0.0 ± 0.0
3.822ThrGly: 3.822 ± 1.222
0.0ThrHis: 0.0 ± 0.0
5.096ThrIle: 5.096 ± 0.687
1.274ThrLys: 1.274 ± 0.699
7.643ThrLeu: 7.643 ± 2.444
2.548ThrMet: 2.548 ± 1.398
3.822ThrAsn: 3.822 ± 0.791
8.917ThrPro: 8.917 ± 5.133
5.096ThrGln: 5.096 ± 1.332
3.822ThrArg: 3.822 ± 0.791
2.548ThrSer: 2.548 ± 1.935
6.369ThrThr: 6.369 ± 3.2
2.548ThrVal: 2.548 ± 1.935
0.0ThrTrp: 0.0 ± 0.0
5.096ThrTyr: 5.096 ± 2.796
0.0ThrXaa: 0.0 ± 0.0
Val
3.822ValAla: 3.822 ± 2.097
0.0ValCys: 0.0 ± 0.0
1.274ValAsp: 1.274 ± 1.123
0.0ValGlu: 0.0 ± 0.0
1.274ValPhe: 1.274 ± 1.475
1.274ValGly: 1.274 ± 1.123
0.0ValHis: 0.0 ± 0.0
1.274ValIle: 1.274 ± 1.123
1.274ValLys: 1.274 ± 0.699
0.0ValLeu: 0.0 ± 0.0
2.548ValMet: 2.548 ± 0.838
2.548ValAsn: 2.548 ± 1.398
3.822ValPro: 3.822 ± 1.222
3.822ValGln: 3.822 ± 1.715
6.369ValArg: 6.369 ± 1.293
3.822ValSer: 3.822 ± 1.222
0.0ValThr: 0.0 ± 0.0
1.274ValVal: 1.274 ± 0.699
2.548ValTrp: 2.548 ± 0.674
1.274ValTyr: 1.274 ± 1.123
0.0ValXaa: 0.0 ± 0.0
Trp
3.822TrpAla: 3.822 ± 2.097
0.0TrpCys: 0.0 ± 0.0
2.548TrpAsp: 2.548 ± 1.398
0.0TrpGlu: 0.0 ± 0.0
1.274TrpPhe: 1.274 ± 1.123
1.274TrpGly: 1.274 ± 0.699
3.822TrpHis: 3.822 ± 2.097
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.548TrpLeu: 2.548 ± 0.674
0.0TrpMet: 0.0 ± 0.0
1.274TrpAsn: 1.274 ± 1.123
1.274TrpPro: 1.274 ± 0.699
2.548TrpGln: 2.548 ± 0.674
2.548TrpArg: 2.548 ± 1.398
2.548TrpSer: 2.548 ± 1.398
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.548TrpTrp: 2.548 ± 1.398
1.274TrpTyr: 1.274 ± 1.123
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.096TyrAla: 5.096 ± 2.796
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
1.274TyrGly: 1.274 ± 0.699
1.274TyrHis: 1.274 ± 1.123
0.0TyrIle: 0.0 ± 0.0
3.822TyrLys: 3.822 ± 0.791
1.274TyrLeu: 1.274 ± 0.699
2.548TyrMet: 2.548 ± 1.398
1.274TyrAsn: 1.274 ± 1.123
2.548TyrPro: 2.548 ± 1.398
0.0TyrGln: 0.0 ± 0.0
3.822TyrArg: 3.822 ± 1.273
5.096TyrSer: 5.096 ± 1.348
0.0TyrThr: 0.0 ± 0.0
2.548TyrVal: 2.548 ± 1.398
1.274TyrTrp: 1.274 ± 0.699
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (786 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski