Ophiocordyceps australis

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; sordariomyceta; Sordariomycetes; Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps

Average proteome isoelectric point is 6.78

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8168 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2C5XHB8|A0A2C5XHB8_9HYPO Homeobox domain-containing protein OS=Ophiocordyceps australis OX=1399860 GN=CDD81_6872 PE=4 SV=1
MM1 pKa = 7.68SDD3 pKa = 3.05MAGEE7 pKa = 4.19LQPLGSQATSIAVDD21 pKa = 3.62EE22 pKa = 4.53FTKK25 pKa = 10.51FLKK28 pKa = 10.85NSVPTAMIPIDD39 pKa = 3.15IHH41 pKa = 5.91KK42 pKa = 10.36CLVYY46 pKa = 9.58TANCILDD53 pKa = 3.56VAKK56 pKa = 10.64EE57 pKa = 4.18SGVEE61 pKa = 3.8LSEE64 pKa = 3.69ITIGRR69 pKa = 11.84DD70 pKa = 4.05CMPTWPCCFWDD81 pKa = 3.78EE82 pKa = 4.5RR83 pKa = 11.84VEE85 pKa = 4.27TLHH88 pKa = 6.1EE89 pKa = 4.59TIQKK93 pKa = 10.13GLVVSQMVRR102 pKa = 11.84SLGDD106 pKa = 3.16FVRR109 pKa = 11.84LEE111 pKa = 4.48IINKK115 pKa = 9.73GNMKK119 pKa = 10.1LDD121 pKa = 3.7EE122 pKa = 4.43ARR124 pKa = 11.84KK125 pKa = 9.85QGISLQSVYY134 pKa = 10.16IGRR137 pKa = 11.84GLLPAWPVQAKK148 pKa = 9.93QDD150 pKa = 3.13VDD152 pKa = 4.09LAIEE156 pKa = 4.37GAFEE160 pKa = 4.35VQDD163 pKa = 3.42EE164 pKa = 5.21SYY166 pKa = 11.67NSDD169 pKa = 3.21TDD171 pKa = 3.57GGSDD175 pKa = 3.45AEE177 pKa = 4.78GYY179 pKa = 7.94KK180 pKa = 9.91TDD182 pKa = 4.17GSDD185 pKa = 3.42EE186 pKa = 4.46TVTEE190 pKa = 4.32ATQLTPLAAQFKK202 pKa = 10.09QADD205 pKa = 4.3LSCSDD210 pKa = 4.43SDD212 pKa = 4.68GDD214 pKa = 5.24DD215 pKa = 3.68AGSDD219 pKa = 3.57DD220 pKa = 6.59DD221 pKa = 4.68YY222 pKa = 11.86DD223 pKa = 3.74QVIYY227 pKa = 10.25MNNFVCPEE235 pKa = 4.91PIYY238 pKa = 11.02EE239 pKa = 5.76DD240 pKa = 3.39IDD242 pKa = 3.98DD243 pKa = 4.0VNIAHH248 pKa = 6.32NVDD251 pKa = 3.99VVDD254 pKa = 4.3HH255 pKa = 6.11SQMVDD260 pKa = 3.03MQVFLVEE267 pKa = 4.41DD268 pKa = 4.5DD269 pKa = 3.76EE270 pKa = 7.19DD271 pKa = 3.84IAHH274 pKa = 6.24VPMAEE279 pKa = 4.12LAVDD283 pKa = 3.59YY284 pKa = 10.91DD285 pKa = 3.85GYY287 pKa = 11.38EE288 pKa = 4.34YY289 pKa = 11.5YY290 pKa = 10.8CGDD293 pKa = 4.15SGDD296 pKa = 3.72EE297 pKa = 4.67AIDD300 pKa = 3.97IEE302 pKa = 4.39LQDD305 pKa = 3.71GEE307 pKa = 4.99LYY309 pKa = 10.99CFVGRR314 pKa = 11.84EE315 pKa = 3.88KK316 pKa = 10.81SDD318 pKa = 3.49EE319 pKa = 4.09EE320 pKa = 4.65GEE322 pKa = 3.96EE323 pKa = 4.25DD324 pKa = 3.73EE325 pKa = 5.24QEE327 pKa = 4.18EE328 pKa = 4.52AMPMSDD334 pKa = 3.66GQLSSDD340 pKa = 3.88SQHH343 pKa = 7.2DD344 pKa = 3.87DD345 pKa = 3.5VGDD348 pKa = 3.76SDD350 pKa = 4.58EE351 pKa = 5.95DD352 pKa = 3.88GTATTTDD359 pKa = 3.96DD360 pKa = 4.92DD361 pKa = 4.7SSLSEE366 pKa = 4.06GSEE369 pKa = 3.89SDD371 pKa = 3.71TSIEE375 pKa = 4.2DD376 pKa = 3.21

Molecular weight: 41.26 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2C5XC56|A0A2C5XC56_9HYPO Uncharacterized protein OS=Ophiocordyceps australis OX=1399860 GN=CDD81_5251 PE=3 SV=1
MM1 pKa = 7.7AISARR6 pKa = 11.84RR7 pKa = 11.84VILPQWQWRR16 pKa = 11.84CVSSSTSSSQHH27 pKa = 5.87RR28 pKa = 11.84LPHH31 pKa = 6.29RR32 pKa = 11.84LHH34 pKa = 6.87RR35 pKa = 11.84PNPPRR40 pKa = 11.84KK41 pKa = 7.94HH42 pKa = 5.5TAPTSQPEE50 pKa = 4.31TLLSLWRR57 pKa = 11.84RR58 pKa = 11.84SWMPLTGAALAAGFLGFYY76 pKa = 10.38IVGTVAASLRR86 pKa = 11.84QPCQLPNTACRR97 pKa = 11.84TAIPTGRR104 pKa = 11.84PSALTGEE111 pKa = 4.34NVEE114 pKa = 4.36TFDD117 pKa = 6.42RR118 pKa = 11.84EE119 pKa = 4.19LDD121 pKa = 3.51WPEE124 pKa = 2.82WWMGISRR131 pKa = 11.84LRR133 pKa = 11.84RR134 pKa = 11.84RR135 pKa = 11.84IGALAAGDD143 pKa = 3.87VLEE146 pKa = 4.44VAVGTGRR153 pKa = 11.84NLTFYY158 pKa = 9.31QWKK161 pKa = 8.0PASPARR167 pKa = 11.84KK168 pKa = 8.9NRR170 pKa = 11.84PRR172 pKa = 11.84GITSFTGLDD181 pKa = 3.1ISADD185 pKa = 3.76MLVLAQKK192 pKa = 10.74RR193 pKa = 11.84LDD195 pKa = 4.04LLHH198 pKa = 6.57TPATQFQSPTRR209 pKa = 11.84SSSAQNRR216 pKa = 11.84LRR218 pKa = 11.84LITANVQEE226 pKa = 5.06PLPPPPVTSVPVPGSTKK243 pKa = 10.05PCAKK247 pKa = 9.83YY248 pKa = 9.08DD249 pKa = 3.93TIIQTFGLCSVADD262 pKa = 3.63PVRR265 pKa = 11.84ALEE268 pKa = 4.06NLAAAVKK275 pKa = 9.27PGSGRR280 pKa = 11.84IILLEE285 pKa = 4.22HH286 pKa = 5.7GRR288 pKa = 11.84GWLGLVNGLLDD299 pKa = 3.94RR300 pKa = 11.84FAPGHH305 pKa = 4.86YY306 pKa = 9.68SKK308 pKa = 11.27YY309 pKa = 8.15GCWWNRR315 pKa = 11.84DD316 pKa = 3.13IEE318 pKa = 4.4GLIHH322 pKa = 5.74EE323 pKa = 6.17AIRR326 pKa = 11.84STPQLEE332 pKa = 4.1LVKK335 pKa = 10.2LHH337 pKa = 7.05RR338 pKa = 11.84PNIWQLGTIVWAEE351 pKa = 3.95LRR353 pKa = 11.84VALPPEE359 pKa = 4.34KK360 pKa = 10.73SS361 pKa = 3.09

Molecular weight: 40.01 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8168

0

8168

4004734

66

5810

490.3

54.02

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.788 ± 0.028

1.397 ± 0.011

5.868 ± 0.02

5.707 ± 0.029

3.394 ± 0.017

6.798 ± 0.026

2.64 ± 0.012

4.223 ± 0.021

4.542 ± 0.027

9.173 ± 0.032

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.337 ± 0.01

3.242 ± 0.014

5.997 ± 0.032

4.492 ± 0.023

6.595 ± 0.024

8.291 ± 0.035

5.425 ± 0.019

6.162 ± 0.024

1.43 ± 0.01

2.465 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski