Amino acid dipepetide frequency for Beihai tombus-like virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.221AlaAla: 6.221 ± 0.249
2.333AlaCys: 2.333 ± 0.291
3.11AlaAsp: 3.11 ± 1.662
3.11AlaGlu: 3.11 ± 1.662
3.888AlaPhe: 3.888 ± 4.072
3.888AlaGly: 3.888 ± 2.077
2.333AlaHis: 2.333 ± 0.291
3.888AlaIle: 3.888 ± 2.535
1.555AlaLys: 1.555 ± 0.831
6.998AlaLeu: 6.998 ± 0.664
1.555AlaMet: 1.555 ± 0.706
1.555AlaAsn: 1.555 ± 0.831
3.888AlaPro: 3.888 ± 4.072
0.778AlaGln: 0.778 ± 0.415
10.109AlaArg: 10.109 ± 3.863
6.221AlaSer: 6.221 ± 1.289
3.11AlaThr: 3.11 ± 1.413
3.888AlaVal: 3.888 ± 2.077
0.0AlaTrp: 0.0 ± 0.0
3.11AlaTyr: 3.11 ± 2.95
0.0AlaXaa: 0.0 ± 0.0
Cys
0.778CysAla: 0.778 ± 0.415
1.555CysCys: 1.555 ± 0.831
0.778CysAsp: 0.778 ± 0.415
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.778CysGly: 0.778 ± 1.122
0.0CysHis: 0.0 ± 0.0
2.333CysIle: 2.333 ± 1.246
1.555CysLys: 1.555 ± 0.706
2.333CysLeu: 2.333 ± 1.246
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.778CysPro: 0.778 ± 0.415
0.778CysGln: 0.778 ± 1.122
0.778CysArg: 0.778 ± 0.415
1.555CysSer: 1.555 ± 0.831
2.333CysThr: 2.333 ± 0.291
1.555CysVal: 1.555 ± 0.706
0.778CysTrp: 0.778 ± 0.415
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.888AspAla: 3.888 ± 2.535
2.333AspCys: 2.333 ± 0.291
3.888AspAsp: 3.888 ± 0.54
3.11AspGlu: 3.11 ± 1.662
1.555AspPhe: 1.555 ± 0.706
1.555AspGly: 1.555 ± 0.706
0.0AspHis: 0.0 ± 0.0
5.443AspIle: 5.443 ± 2.908
3.888AspLys: 3.888 ± 2.077
2.333AspLeu: 2.333 ± 1.246
2.333AspMet: 2.333 ± 1.246
4.666AspAsn: 4.666 ± 0.955
1.555AspPro: 1.555 ± 0.831
1.555AspGln: 1.555 ± 0.706
3.11AspArg: 3.11 ± 1.413
3.11AspSer: 3.11 ± 1.662
3.11AspThr: 3.11 ± 1.662
6.221AspVal: 6.221 ± 0.249
0.0AspTrp: 0.0 ± 0.0
2.333AspTyr: 2.333 ± 0.291
0.0AspXaa: 0.0 ± 0.0
Glu
3.11GluAla: 3.11 ± 0.124
0.0GluCys: 0.0 ± 0.0
5.443GluAsp: 5.443 ± 1.371
0.778GluGlu: 0.778 ± 0.415
0.778GluPhe: 0.778 ± 1.122
3.11GluGly: 3.11 ± 1.662
2.333GluHis: 2.333 ± 1.828
5.443GluIle: 5.443 ± 1.371
3.11GluLys: 3.11 ± 1.662
4.666GluLeu: 4.666 ± 0.955
2.333GluMet: 2.333 ± 0.291
3.11GluAsn: 3.11 ± 0.124
0.778GluPro: 0.778 ± 0.415
3.888GluGln: 3.888 ± 2.077
2.333GluArg: 2.333 ± 1.246
2.333GluSer: 2.333 ± 1.246
3.11GluThr: 3.11 ± 1.662
2.333GluVal: 2.333 ± 1.246
1.555GluTrp: 1.555 ± 0.831
0.778GluTyr: 0.778 ± 1.122
0.0GluXaa: 0.0 ± 0.0
Phe
3.11PheAla: 3.11 ± 2.95
0.778PheCys: 0.778 ± 0.415
3.888PheAsp: 3.888 ± 0.54
1.555PheGlu: 1.555 ± 0.831
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
0.778PheIle: 0.778 ± 0.415
1.555PheLys: 1.555 ± 0.831
0.0PheLeu: 0.0 ± 0.0
0.778PheMet: 0.778 ± 1.122
2.333PheAsn: 2.333 ± 0.291
1.555PhePro: 1.555 ± 0.706
0.778PheGln: 0.778 ± 0.415
0.778PheArg: 0.778 ± 1.122
0.778PheSer: 0.778 ± 0.415
1.555PheThr: 1.555 ± 0.831
2.333PheVal: 2.333 ± 1.246
0.778PheTrp: 0.778 ± 1.122
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.11GlyAla: 3.11 ± 0.124
0.778GlyCys: 0.778 ± 1.122
2.333GlyAsp: 2.333 ± 1.246
2.333GlyGlu: 2.333 ± 0.291
2.333GlyPhe: 2.333 ± 1.246
6.998GlyGly: 6.998 ± 3.948
3.888GlyHis: 3.888 ± 2.535
2.333GlyIle: 2.333 ± 1.828
1.555GlyLys: 1.555 ± 0.831
5.443GlyLeu: 5.443 ± 0.167
0.778GlyMet: 0.778 ± 0.415
5.443GlyAsn: 5.443 ± 0.167
5.443GlyPro: 5.443 ± 0.167
0.778GlyGln: 0.778 ± 0.415
0.0GlyArg: 0.0 ± 0.0
6.998GlySer: 6.998 ± 0.664
7.776GlyThr: 7.776 ± 3.532
2.333GlyVal: 2.333 ± 1.246
0.0GlyTrp: 0.0 ± 0.0
4.666GlyTyr: 4.666 ± 0.582
0.0GlyXaa: 0.0 ± 0.0
His
0.778HisAla: 0.778 ± 0.415
0.778HisCys: 0.778 ± 0.415
1.555HisAsp: 1.555 ± 0.831
0.0HisGlu: 0.0 ± 0.0
0.778HisPhe: 0.778 ± 0.415
3.11HisGly: 3.11 ± 0.124
0.778HisHis: 0.778 ± 0.415
0.778HisIle: 0.778 ± 0.415
1.555HisLys: 1.555 ± 0.831
2.333HisLeu: 2.333 ± 0.291
0.0HisMet: 0.0 ± 0.0
2.333HisAsn: 2.333 ± 0.291
2.333HisPro: 2.333 ± 1.246
0.778HisGln: 0.778 ± 0.415
3.11HisArg: 3.11 ± 1.662
5.443HisSer: 5.443 ± 4.779
0.778HisThr: 0.778 ± 0.415
1.555HisVal: 1.555 ± 0.706
0.778HisTrp: 0.778 ± 1.122
2.333HisTyr: 2.333 ± 1.246
0.0HisXaa: 0.0 ± 0.0
Ile
4.666IleAla: 4.666 ± 0.955
0.0IleCys: 0.0 ± 0.0
4.666IleAsp: 4.666 ± 0.955
3.888IleGlu: 3.888 ± 2.077
0.0IlePhe: 0.0 ± 0.0
3.888IleGly: 3.888 ± 0.54
0.778IleHis: 0.778 ± 0.415
2.333IleIle: 2.333 ± 1.246
3.888IleLys: 3.888 ± 2.077
5.443IleLeu: 5.443 ± 0.167
0.778IleMet: 0.778 ± 0.415
3.11IleAsn: 3.11 ± 0.124
5.443IlePro: 5.443 ± 1.371
1.555IleGln: 1.555 ± 0.706
3.888IleArg: 3.888 ± 2.077
3.11IleSer: 3.11 ± 1.413
3.11IleThr: 3.11 ± 0.124
1.555IleVal: 1.555 ± 0.831
0.0IleTrp: 0.0 ± 0.0
6.221IleTyr: 6.221 ± 3.323
0.0IleXaa: 0.0 ± 0.0
Lys
6.221LysAla: 6.221 ± 0.249
0.778LysCys: 0.778 ± 0.415
4.666LysAsp: 4.666 ± 0.582
3.888LysGlu: 3.888 ± 0.54
1.555LysPhe: 1.555 ± 0.706
2.333LysGly: 2.333 ± 0.291
2.333LysHis: 2.333 ± 0.291
3.888LysIle: 3.888 ± 0.54
1.555LysLys: 1.555 ± 0.706
5.443LysLeu: 5.443 ± 0.167
0.778LysMet: 0.778 ± 0.415
1.555LysAsn: 1.555 ± 0.706
3.11LysPro: 3.11 ± 1.662
3.11LysGln: 3.11 ± 1.413
6.998LysArg: 6.998 ± 2.411
3.888LysSer: 3.888 ± 0.998
6.221LysThr: 6.221 ± 1.289
3.11LysVal: 3.11 ± 1.662
0.778LysTrp: 0.778 ± 1.122
1.555LysTyr: 1.555 ± 2.244
0.0LysXaa: 0.0 ± 0.0
Leu
7.776LeuAla: 7.776 ± 1.995
1.555LeuCys: 1.555 ± 0.706
3.888LeuAsp: 3.888 ± 0.998
6.221LeuGlu: 6.221 ± 0.249
0.778LeuPhe: 0.778 ± 0.415
2.333LeuGly: 2.333 ± 1.246
3.888LeuHis: 3.888 ± 2.077
5.443LeuIle: 5.443 ± 1.371
3.11LeuLys: 3.11 ± 1.662
6.998LeuLeu: 6.998 ± 0.873
0.778LeuMet: 0.778 ± 1.122
4.666LeuAsn: 4.666 ± 0.955
3.888LeuPro: 3.888 ± 0.998
3.888LeuGln: 3.888 ± 2.077
6.221LeuArg: 6.221 ± 1.786
3.888LeuSer: 3.888 ± 0.54
4.666LeuThr: 4.666 ± 2.492
3.888LeuVal: 3.888 ± 4.072
1.555LeuTrp: 1.555 ± 0.706
0.778LeuTyr: 0.778 ± 0.415
0.0LeuXaa: 0.0 ± 0.0
Met
3.11MetAla: 3.11 ± 1.662
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.555MetGlu: 1.555 ± 0.831
1.555MetPhe: 1.555 ± 0.831
0.778MetGly: 0.778 ± 1.122
1.555MetHis: 1.555 ± 0.831
1.555MetIle: 1.555 ± 0.831
2.333MetLys: 2.333 ± 1.828
0.778MetLeu: 0.778 ± 0.415
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.555MetPro: 1.555 ± 0.706
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.333MetSer: 2.333 ± 1.828
0.778MetThr: 0.778 ± 1.122
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.11MetTyr: 3.11 ± 2.95
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.555AsnCys: 1.555 ± 0.831
2.333AsnAsp: 2.333 ± 1.246
3.11AsnGlu: 3.11 ± 0.124
0.778AsnPhe: 0.778 ± 0.415
2.333AsnGly: 2.333 ± 1.828
2.333AsnHis: 2.333 ± 0.291
4.666AsnIle: 4.666 ± 2.492
5.443AsnLys: 5.443 ± 0.167
2.333AsnLeu: 2.333 ± 0.291
0.778AsnMet: 0.778 ± 0.415
1.555AsnAsn: 1.555 ± 0.831
1.555AsnPro: 1.555 ± 0.706
0.778AsnGln: 0.778 ± 0.415
3.11AsnArg: 3.11 ± 1.662
5.443AsnSer: 5.443 ± 1.704
2.333AsnThr: 2.333 ± 0.291
2.333AsnVal: 2.333 ± 1.246
0.0AsnTrp: 0.0 ± 0.0
1.555AsnTyr: 1.555 ± 0.831
0.0AsnXaa: 0.0 ± 0.0
Pro
3.888ProAla: 3.888 ± 0.54
0.778ProCys: 0.778 ± 1.122
5.443ProAsp: 5.443 ± 1.704
1.555ProGlu: 1.555 ± 0.831
0.0ProPhe: 0.0 ± 0.0
7.776ProGly: 7.776 ± 3.532
1.555ProHis: 1.555 ± 0.831
1.555ProIle: 1.555 ± 0.831
5.443ProLys: 5.443 ± 4.779
3.11ProLeu: 3.11 ± 1.662
1.555ProMet: 1.555 ± 0.831
1.555ProAsn: 1.555 ± 0.831
0.778ProPro: 0.778 ± 0.415
0.778ProGln: 0.778 ± 1.122
1.555ProArg: 1.555 ± 0.831
7.776ProSer: 7.776 ± 5.07
2.333ProThr: 2.333 ± 0.291
5.443ProVal: 5.443 ± 1.704
0.778ProTrp: 0.778 ± 0.415
1.555ProTyr: 1.555 ± 0.831
0.0ProXaa: 0.0 ± 0.0
Gln
1.555GlnAla: 1.555 ± 0.831
1.555GlnCys: 1.555 ± 0.831
1.555GlnAsp: 1.555 ± 0.831
3.11GlnGlu: 3.11 ± 0.124
0.0GlnPhe: 0.0 ± 0.0
3.11GlnGly: 3.11 ± 0.124
0.778GlnHis: 0.778 ± 0.415
2.333GlnIle: 2.333 ± 0.291
3.888GlnLys: 3.888 ± 2.535
4.666GlnLeu: 4.666 ± 2.492
0.0GlnMet: 0.0 ± 0.0
0.778GlnAsn: 0.778 ± 0.415
2.333GlnPro: 2.333 ± 1.246
1.555GlnGln: 1.555 ± 0.706
3.11GlnArg: 3.11 ± 0.124
1.555GlnSer: 1.555 ± 0.706
1.555GlnThr: 1.555 ± 0.706
3.11GlnVal: 3.11 ± 1.413
0.0GlnTrp: 0.0 ± 0.0
0.778GlnTyr: 0.778 ± 0.415
0.0GlnXaa: 0.0 ± 0.0
Arg
7.776ArgAla: 7.776 ± 0.458
0.778ArgCys: 0.778 ± 0.415
3.888ArgAsp: 3.888 ± 0.54
1.555ArgGlu: 1.555 ± 0.706
1.555ArgPhe: 1.555 ± 0.831
3.888ArgGly: 3.888 ± 0.54
4.666ArgHis: 4.666 ± 2.492
2.333ArgIle: 2.333 ± 1.246
3.11ArgLys: 3.11 ± 0.124
6.221ArgLeu: 6.221 ± 0.249
1.555ArgMet: 1.555 ± 0.706
4.666ArgAsn: 4.666 ± 2.492
3.888ArgPro: 3.888 ± 2.535
2.333ArgGln: 2.333 ± 1.246
3.11ArgArg: 3.11 ± 1.662
2.333ArgSer: 2.333 ± 0.291
3.888ArgThr: 3.888 ± 2.077
3.11ArgVal: 3.11 ± 0.124
0.778ArgTrp: 0.778 ± 0.415
3.11ArgTyr: 3.11 ± 0.124
0.0ArgXaa: 0.0 ± 0.0
Ser
4.666SerAla: 4.666 ± 2.492
1.555SerCys: 1.555 ± 0.831
2.333SerAsp: 2.333 ± 0.291
3.888SerGlu: 3.888 ± 0.54
3.11SerPhe: 3.11 ± 0.124
7.776SerGly: 7.776 ± 1.995
0.0SerHis: 0.0 ± 0.0
4.666SerIle: 4.666 ± 2.492
7.776SerLys: 7.776 ± 3.532
6.998SerLeu: 6.998 ± 0.873
0.778SerMet: 0.778 ± 0.415
1.555SerAsn: 1.555 ± 0.706
5.443SerPro: 5.443 ± 6.316
7.776SerGln: 7.776 ± 1.995
3.11SerArg: 3.11 ± 1.662
4.666SerSer: 4.666 ± 2.119
4.666SerThr: 4.666 ± 3.657
3.888SerVal: 3.888 ± 2.535
0.778SerTrp: 0.778 ± 0.415
3.11SerTyr: 3.11 ± 1.413
0.0SerXaa: 0.0 ± 0.0
Thr
5.443ThrAla: 5.443 ± 3.241
0.778ThrCys: 0.778 ± 0.415
0.778ThrAsp: 0.778 ± 1.122
3.11ThrGlu: 3.11 ± 1.662
1.555ThrPhe: 1.555 ± 0.831
4.666ThrGly: 4.666 ± 0.955
3.888ThrHis: 3.888 ± 0.54
2.333ThrIle: 2.333 ± 1.246
1.555ThrLys: 1.555 ± 0.706
3.888ThrLeu: 3.888 ± 0.54
1.555ThrMet: 1.555 ± 2.052
2.333ThrAsn: 2.333 ± 0.291
1.555ThrPro: 1.555 ± 0.831
3.11ThrGln: 3.11 ± 1.662
4.666ThrArg: 4.666 ± 0.955
10.109ThrSer: 10.109 ± 2.286
6.998ThrThr: 6.998 ± 2.411
4.666ThrVal: 4.666 ± 0.582
0.778ThrTrp: 0.778 ± 0.415
3.11ThrTyr: 3.11 ± 1.662
0.0ThrXaa: 0.0 ± 0.0
Val
3.11ValAla: 3.11 ± 1.413
0.0ValCys: 0.0 ± 0.0
3.11ValAsp: 3.11 ± 1.662
5.443ValGlu: 5.443 ± 1.371
2.333ValPhe: 2.333 ± 1.246
5.443ValGly: 5.443 ± 1.704
0.778ValHis: 0.778 ± 1.122
3.888ValIle: 3.888 ± 2.077
3.11ValLys: 3.11 ± 1.413
3.11ValLeu: 3.11 ± 0.124
1.555ValMet: 1.555 ± 1.705
1.555ValAsn: 1.555 ± 0.706
6.221ValPro: 6.221 ± 1.289
1.555ValGln: 1.555 ± 0.831
4.666ValArg: 4.666 ± 0.582
4.666ValSer: 4.666 ± 0.582
3.888ValThr: 3.888 ± 2.077
4.666ValVal: 4.666 ± 2.119
0.778ValTrp: 0.778 ± 1.122
3.11ValTyr: 3.11 ± 1.662
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.778TrpGlu: 0.778 ± 0.415
0.778TrpPhe: 0.778 ± 1.122
0.778TrpGly: 0.778 ± 0.415
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.555TrpLeu: 1.555 ± 0.706
0.0TrpMet: 0.0 ± 0.0
0.778TrpAsn: 0.778 ± 0.415
0.778TrpPro: 0.778 ± 1.122
0.0TrpGln: 0.0 ± 0.0
0.778TrpArg: 0.778 ± 1.122
0.0TrpSer: 0.0 ± 0.0
0.778TrpThr: 0.778 ± 0.415
3.11TrpVal: 3.11 ± 0.124
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.333TyrAla: 2.333 ± 1.246
0.778TyrCys: 0.778 ± 0.415
2.333TyrAsp: 2.333 ± 1.246
2.333TyrGlu: 2.333 ± 0.291
0.0TyrPhe: 0.0 ± 0.0
0.778TyrGly: 0.778 ± 0.415
0.0TyrHis: 0.0 ± 0.0
2.333TyrIle: 2.333 ± 1.828
7.776TyrLys: 7.776 ± 1.995
1.555TyrLeu: 1.555 ± 2.244
2.333TyrMet: 2.333 ± 0.291
0.778TyrAsn: 0.778 ± 0.415
2.333TyrPro: 2.333 ± 0.291
1.555TyrGln: 1.555 ± 0.706
3.11TyrArg: 3.11 ± 1.413
2.333TyrSer: 2.333 ± 1.246
4.666TyrThr: 4.666 ± 2.492
3.888TyrVal: 3.888 ± 0.54
0.0TyrTrp: 0.0 ± 0.0
1.555TyrTyr: 1.555 ± 0.706
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1287 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski