Amino acid dipepetide frequency for Botryobasidium botryosum FD-172 SS1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.712AlaAla: 9.712 ± 0.055	1.37AlaCys: 1.37 ± 0.017	4.196AlaAsp: 4.196 ± 0.027	4.918AlaGlu: 4.918 ± 0.039	3.483AlaPhe: 3.483 ± 0.029	5.812AlaGly: 5.812 ± 0.037	2.418AlaHis: 2.418 ± 0.022	4.361AlaIle: 4.361 ± 0.028	3.941AlaLys: 3.941 ± 0.029	9.239AlaLeu: 9.239 ± 0.049	1.887AlaMet: 1.887 ± 0.017	2.761AlaAsn: 2.761 ± 0.023	6.457AlaPro: 6.457 ± 0.046	3.578AlaGln: 3.578 ± 0.027	5.916AlaArg: 5.916 ± 0.037	8.127AlaSer: 8.127 ± 0.049	5.326AlaThr: 5.326 ± 0.034	5.482AlaVal: 5.482 ± 0.033	1.251AlaTrp: 1.251 ± 0.016	2.293AlaTyr: 2.293 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	1.244CysAla: 1.244 ± 0.014	0.274CysCys: 0.274 ± 0.008	0.716CysAsp: 0.716 ± 0.012	0.639CysGlu: 0.639 ± 0.011	0.552CysPhe: 0.552 ± 0.009	1.032CysGly: 1.032 ± 0.014	0.394CysHis: 0.394 ± 0.008	0.758CysIle: 0.758 ± 0.012	0.518CysLys: 0.518 ± 0.009	1.393CysLeu: 1.393 ± 0.018	0.285CysMet: 0.285 ± 0.007	0.411CysAsn: 0.411 ± 0.008	0.973CysPro: 0.973 ± 0.015	0.475CysGln: 0.475 ± 0.009	0.904CysArg: 0.904 ± 0.013	1.051CysSer: 1.051 ± 0.014	0.866CysThr: 0.866 ± 0.012	0.929CysVal: 0.929 ± 0.014	0.255CysTrp: 0.255 ± 0.007	0.349CysTyr: 0.349 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.992AspAla: 4.992 ± 0.031	0.642AspCys: 0.642 ± 0.011	3.825AspAsp: 3.825 ± 0.03	4.029AspGlu: 4.029 ± 0.034	2.039AspPhe: 2.039 ± 0.019	3.864AspGly: 3.864 ± 0.034	1.28AspHis: 1.28 ± 0.017	3.05AspIle: 3.05 ± 0.024	1.958AspLys: 1.958 ± 0.019	4.828AspLeu: 4.828 ± 0.032	1.14AspMet: 1.14 ± 0.012	1.488AspAsn: 1.488 ± 0.016	3.391AspPro: 3.391 ± 0.022	1.501AspGln: 1.501 ± 0.015	2.89AspArg: 2.89 ± 0.026	3.918AspSer: 3.918 ± 0.028	2.865AspThr: 2.865 ± 0.021	3.694AspVal: 3.694 ± 0.024	0.799AspTrp: 0.799 ± 0.011	1.349AspTyr: 1.349 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.096GluAla: 5.096 ± 0.038	0.713GluCys: 0.713 ± 0.011	3.73GluAsp: 3.73 ± 0.031	4.898GluGlu: 4.898 ± 0.046	1.818GluPhe: 1.818 ± 0.017	3.805GluGly: 3.805 ± 0.028	1.377GluHis: 1.377 ± 0.016	2.85GluIle: 2.85 ± 0.024	3.057GluLys: 3.057 ± 0.027	5.347GluLeu: 5.347 ± 0.034	1.275GluMet: 1.275 ± 0.015	1.765GluAsn: 1.765 ± 0.018	2.662GluPro: 2.662 ± 0.024	1.958GluGln: 1.958 ± 0.02	3.977GluArg: 3.977 ± 0.032	4.043GluSer: 4.043 ± 0.03	2.79GluThr: 2.79 ± 0.024	3.415GluVal: 3.415 ± 0.025	0.923GluTrp: 0.923 ± 0.013	1.516GluTyr: 1.516 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	3.293PheAla: 3.293 ± 0.022	0.587PheCys: 0.587 ± 0.011	2.206PheAsp: 2.206 ± 0.023	1.977PheGlu: 1.977 ± 0.02	1.598PhePhe: 1.598 ± 0.019	2.7PheGly: 2.7 ± 0.027	1.037PheHis: 1.037 ± 0.014	1.878PheIle: 1.878 ± 0.019	1.463PheLys: 1.463 ± 0.016	3.537PheLeu: 3.537 ± 0.025	0.71PheMet: 0.71 ± 0.01	1.3PheAsn: 1.3 ± 0.016	2.245PhePro: 2.245 ± 0.02	1.227PheGln: 1.227 ± 0.014	2.001PheArg: 2.001 ± 0.02	3.186PheSer: 3.186 ± 0.025	2.182PheThr: 2.182 ± 0.018	2.38PheVal: 2.38 ± 0.021	0.578PheTrp: 0.578 ± 0.011	1.007PheTyr: 1.007 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.768GlyAla: 5.768 ± 0.041	0.93GlyCys: 0.93 ± 0.015	3.58GlyAsp: 3.58 ± 0.029	3.592GlyGlu: 3.592 ± 0.026	2.444GlyPhe: 2.444 ± 0.022	5.706GlyGly: 5.706 ± 0.05	1.708GlyHis: 1.708 ± 0.019	3.09GlyIle: 3.09 ± 0.024	3.257GlyLys: 3.257 ± 0.026	5.672GlyLeu: 5.672 ± 0.032	1.403GlyMet: 1.403 ± 0.017	2.196GlyAsn: 2.196 ± 0.018	3.387GlyPro: 3.387 ± 0.028	2.118GlyGln: 2.118 ± 0.023	4.025GlyArg: 4.025 ± 0.03	5.576GlySer: 5.576 ± 0.035	3.769GlyThr: 3.769 ± 0.023	4.302GlyVal: 4.302 ± 0.035	1.084GlyTrp: 1.084 ± 0.015	1.808GlyTyr: 1.808 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	2.418HisAla: 2.418 ± 0.022	0.376HisCys: 0.376 ± 0.009	1.325HisAsp: 1.325 ± 0.016	1.253HisGlu: 1.253 ± 0.015	1.063HisPhe: 1.063 ± 0.013	1.708HisGly: 1.708 ± 0.017	0.987HisHis: 0.987 ± 0.016	1.476HisIle: 1.476 ± 0.016	0.903HisLys: 0.903 ± 0.012	2.766HisLeu: 2.766 ± 0.022	0.503HisMet: 0.503 ± 0.009	0.834HisAsn: 0.834 ± 0.011	2.277HisPro: 2.277 ± 0.022	0.914HisGln: 0.914 ± 0.014	1.741HisArg: 1.741 ± 0.019	2.195HisSer: 2.195 ± 0.023	1.634HisThr: 1.634 ± 0.018	1.591HisVal: 1.591 ± 0.017	0.366HisTrp: 0.366 ± 0.008	0.712HisTyr: 0.712 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.413IleAla: 4.413 ± 0.028	0.77IleCys: 0.77 ± 0.013	2.723IleAsp: 2.723 ± 0.021	2.66IleGlu: 2.66 ± 0.025	2.033IlePhe: 2.033 ± 0.018	2.921IleGly: 2.921 ± 0.025	1.339IleHis: 1.339 ± 0.015	2.51IleIle: 2.51 ± 0.023	2.037IleLys: 2.037 ± 0.019	4.654IleLeu: 4.654 ± 0.029	0.899IleMet: 0.899 ± 0.013	1.635IleAsn: 1.635 ± 0.016	3.367IlePro: 3.367 ± 0.024	1.761IleGln: 1.761 ± 0.019	2.938IleArg: 2.938 ± 0.021	4.03IleSer: 4.03 ± 0.027	2.876IleThr: 2.876 ± 0.022	3.109IleVal: 3.109 ± 0.024	0.729IleTrp: 0.729 ± 0.013	1.317IleTyr: 1.317 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.081LysAla: 4.081 ± 0.027	0.55LysCys: 0.55 ± 0.01	2.352LysAsp: 2.352 ± 0.022	2.909LysGlu: 2.909 ± 0.023	1.387LysPhe: 1.387 ± 0.016	2.853LysGly: 2.853 ± 0.026	1.05LysHis: 1.05 ± 0.014	2.032LysIle: 2.032 ± 0.019	2.816LysLys: 2.816 ± 0.029	3.802LysLeu: 3.802 ± 0.026	0.879LysMet: 0.879 ± 0.013	1.404LysAsn: 1.404 ± 0.016	2.473LysPro: 2.473 ± 0.024	1.402LysGln: 1.402 ± 0.016	3.2LysArg: 3.2 ± 0.026	3.147LysSer: 3.147 ± 0.024	2.367LysThr: 2.367 ± 0.02	2.608LysVal: 2.608 ± 0.022	0.637LysTrp: 0.637 ± 0.011	1.177LysTyr: 1.177 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.896LeuAla: 8.896 ± 0.043	1.472LeuCys: 1.472 ± 0.015	5.209LeuAsp: 5.209 ± 0.028	5.589LeuGlu: 5.589 ± 0.039	3.539LeuPhe: 3.539 ± 0.026	5.818LeuGly: 5.818 ± 0.031	2.772LeuHis: 2.772 ± 0.02	4.148LeuIle: 4.148 ± 0.03	4.018LeuLys: 4.018 ± 0.029	9.082LeuLeu: 9.082 ± 0.05	1.674LeuMet: 1.674 ± 0.017	2.847LeuAsn: 2.847 ± 0.023	6.686LeuPro: 6.686 ± 0.042	3.555LeuGln: 3.555 ± 0.027	6.431LeuArg: 6.431 ± 0.046	8.347LeuSer: 8.347 ± 0.043	5.074LeuThr: 5.074 ± 0.029	5.78LeuVal: 5.78 ± 0.037	1.246LeuTrp: 1.246 ± 0.015	2.401LeuTyr: 2.401 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.888MetAla: 1.888 ± 0.018	0.274MetCys: 0.274 ± 0.007	1.186MetAsp: 1.186 ± 0.015	1.189MetGlu: 1.189 ± 0.019	0.698MetPhe: 0.698 ± 0.012	1.275MetGly: 1.275 ± 0.014	0.543MetHis: 0.543 ± 0.009	0.886MetIle: 0.886 ± 0.013	0.862MetLys: 0.862 ± 0.012	1.774MetLeu: 1.774 ± 0.017	0.473MetMet: 0.473 ± 0.01	0.645MetAsn: 0.645 ± 0.01	1.271MetPro: 1.271 ± 0.016	0.745MetGln: 0.745 ± 0.011	1.32MetArg: 1.32 ± 0.014	1.832MetSer: 1.832 ± 0.019	1.09MetThr: 1.09 ± 0.015	1.143MetVal: 1.143 ± 0.014	0.295MetTrp: 0.295 ± 0.007	0.469MetTyr: 0.469 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.04AsnAla: 3.04 ± 0.022	0.419AsnCys: 0.419 ± 0.009	1.592AsnAsp: 1.592 ± 0.017	1.614AsnGlu: 1.614 ± 0.018	1.172AsnPhe: 1.172 ± 0.014	2.341AsnGly: 2.341 ± 0.022	0.824AsnHis: 0.824 ± 0.012	1.842AsnIle: 1.842 ± 0.016	1.211AsnLys: 1.211 ± 0.015	3.035AsnLeu: 3.035 ± 0.023	0.676AsnMet: 0.676 ± 0.01	1.164AsnAsn: 1.164 ± 0.016	2.428AsnPro: 2.428 ± 0.021	1.063AsnGln: 1.063 ± 0.014	1.706AsnArg: 1.706 ± 0.018	2.377AsnSer: 2.377 ± 0.021	1.932AsnThr: 1.932 ± 0.02	2.139AsnVal: 2.139 ± 0.019	0.455AsnTrp: 0.455 ± 0.009	0.818AsnTyr: 0.818 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	6.461ProAla: 6.461 ± 0.049	0.722ProCys: 0.722 ± 0.013	3.209ProAsp: 3.209 ± 0.024	3.533ProGlu: 3.533 ± 0.028	2.358ProPhe: 2.358 ± 0.02	3.876ProGly: 3.876 ± 0.027	1.904ProHis: 1.904 ± 0.019	2.909ProIle: 2.909 ± 0.023	2.546ProLys: 2.546 ± 0.027	6.099ProLeu: 6.099 ± 0.037	1.103ProMet: 1.103 ± 0.013	2.264ProAsn: 2.264 ± 0.02	7.21ProPro: 7.21 ± 0.071	2.375ProGln: 2.375 ± 0.023	4.209ProArg: 4.209 ± 0.035	7.761ProSer: 7.761 ± 0.05	4.768ProThr: 4.768 ± 0.039	3.743ProVal: 3.743 ± 0.028	0.767ProTrp: 0.767 ± 0.011	1.582ProTyr: 1.582 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.286GlnAla: 3.286 ± 0.025	0.488GlnCys: 0.488 ± 0.009	1.665GlnAsp: 1.665 ± 0.017	1.953GlnGlu: 1.953 ± 0.02	1.14GlnPhe: 1.14 ± 0.014	2.109GlnGly: 2.109 ± 0.021	1.04GlnHis: 1.04 ± 0.015	1.684GlnIle: 1.684 ± 0.017	1.544GlnLys: 1.544 ± 0.019	3.451GlnLeu: 3.451 ± 0.025	0.741GlnMet: 0.741 ± 0.011	1.193GlnAsn: 1.193 ± 0.015	2.346GlnPro: 2.346 ± 0.028	1.744GlnGln: 1.744 ± 0.041	2.412GlnArg: 2.412 ± 0.02	2.843GlnSer: 2.843 ± 0.026	1.942GlnThr: 1.942 ± 0.018	1.995GlnVal: 1.995 ± 0.016	0.519GlnTrp: 0.519 ± 0.009	0.984GlnTyr: 0.984 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	6.044ArgAla: 6.044 ± 0.036	0.932ArgCys: 0.932 ± 0.013	3.315ArgAsp: 3.315 ± 0.029	3.806ArgGlu: 3.806 ± 0.033	2.208ArgPhe: 2.208 ± 0.021	3.903ArgGly: 3.903 ± 0.03	1.725ArgHis: 1.725 ± 0.018	3.058ArgIle: 3.058 ± 0.024	3.038ArgLys: 3.038 ± 0.022	6.063ArgLeu: 6.063 ± 0.035	1.326ArgMet: 1.326 ± 0.016	1.983ArgAsn: 1.983 ± 0.019	4.008ArgPro: 4.008 ± 0.03	2.207ArgGln: 2.207 ± 0.022	5.184ArgArg: 5.184 ± 0.041	5.16ArgSer: 5.16 ± 0.039	3.577ArgThr: 3.577 ± 0.027	3.897ArgVal: 3.897 ± 0.029	1.087ArgTrp: 1.087 ± 0.014	1.586ArgTyr: 1.586 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	7.686SerAla: 7.686 ± 0.041	1.042SerCys: 1.042 ± 0.016	4.112SerAsp: 4.112 ± 0.03	3.92SerGlu: 3.92 ± 0.031	3.179SerPhe: 3.179 ± 0.024	5.553SerGly: 5.553 ± 0.033	2.357SerHis: 2.357 ± 0.023	4.061SerIle: 4.061 ± 0.024	3.291SerLys: 3.291 ± 0.024	8.229SerLeu: 8.229 ± 0.045	1.626SerMet: 1.626 ± 0.018	2.724SerAsn: 2.724 ± 0.021	6.827SerPro: 6.827 ± 0.054	2.956SerGln: 2.956 ± 0.024	5.371SerArg: 5.371 ± 0.039	9.271SerSer: 9.271 ± 0.069	5.908SerThr: 5.908 ± 0.037	4.872SerVal: 4.872 ± 0.033	1.082SerTrp: 1.082 ± 0.013	2.036SerTyr: 2.036 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.248ThrAla: 5.248 ± 0.027	0.825ThrCys: 0.825 ± 0.013	2.556ThrAsp: 2.556 ± 0.021	2.6ThrGlu: 2.6 ± 0.022	2.323ThrPhe: 2.323 ± 0.021	3.611ThrGly: 3.611 ± 0.025	1.583ThrHis: 1.583 ± 0.017	3.064ThrIle: 3.064 ± 0.026	2.244ThrLys: 2.244 ± 0.021	5.845ThrLeu: 5.845 ± 0.033	1.116ThrMet: 1.116 ± 0.013	1.823ThrAsn: 1.823 ± 0.02	5.232ThrPro: 5.232 ± 0.037	1.922ThrGln: 1.922 ± 0.019	3.526ThrArg: 3.526 ± 0.028	5.467ThrSer: 5.467 ± 0.034	4.064ThrThr: 4.064 ± 0.033	3.443ThrVal: 3.443 ± 0.024	0.802ThrTrp: 0.802 ± 0.012	1.512ThrTyr: 1.512 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.539ValAla: 5.539 ± 0.032	0.957ValCys: 0.957 ± 0.013	3.599ValAsp: 3.599 ± 0.027	3.722ValGlu: 3.722 ± 0.028	2.45ValPhe: 2.45 ± 0.022	3.829ValGly: 3.829 ± 0.029	1.611ValHis: 1.611 ± 0.015	2.942ValIle: 2.942 ± 0.024	2.645ValLys: 2.645 ± 0.024	5.981ValLeu: 5.981 ± 0.034	1.213ValMet: 1.213 ± 0.017	1.924ValAsn: 1.924 ± 0.018	3.944ValPro: 3.944 ± 0.028	2.198ValGln: 2.198 ± 0.02	3.765ValArg: 3.765 ± 0.029	4.721ValSer: 4.721 ± 0.031	3.332ValThr: 3.332 ± 0.026	4.387ValVal: 4.387 ± 0.032	0.94ValTrp: 0.94 ± 0.012	1.679ValTyr: 1.679 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.236TrpAla: 1.236 ± 0.014	0.254TrpCys: 0.254 ± 0.006	0.934TrpAsp: 0.934 ± 0.015	0.878TrpGlu: 0.878 ± 0.013	0.528TrpPhe: 0.528 ± 0.009	0.916TrpGly: 0.916 ± 0.013	0.352TrpHis: 0.352 ± 0.007	0.75TrpIle: 0.75 ± 0.011	0.782TrpLys: 0.782 ± 0.012	1.278TrpLeu: 1.278 ± 0.015	0.359TrpMet: 0.359 ± 0.007	0.553TrpAsn: 0.553 ± 0.01	0.612TrpPro: 0.612 ± 0.011	0.487TrpGln: 0.487 ± 0.008	1.038TrpArg: 1.038 ± 0.014	1.094TrpSer: 1.094 ± 0.015	0.871TrpThr: 0.871 ± 0.012	0.896TrpVal: 0.896 ± 0.013	0.286TrpTrp: 0.286 ± 0.008	0.39TrpTyr: 0.39 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.191TyrAla: 2.191 ± 0.019	0.424TyrCys: 0.424 ± 0.009	1.514TyrAsp: 1.514 ± 0.015	1.335TyrGlu: 1.335 ± 0.014	1.081TyrPhe: 1.081 ± 0.012	1.777TyrGly: 1.777 ± 0.02	0.741TyrHis: 0.741 ± 0.012	1.376TyrIle: 1.376 ± 0.014	0.993TyrLys: 0.993 ± 0.014	2.51TyrLeu: 2.51 ± 0.021	0.565TyrMet: 0.565 ± 0.01	0.933TyrAsn: 0.933 ± 0.011	1.604TyrPro: 1.604 ± 0.021	0.897TyrGln: 0.897 ± 0.012	1.553TyrArg: 1.553 ± 0.016	1.952TyrSer: 1.952 ± 0.017	1.577TyrThr: 1.577 ± 0.014	1.571TyrVal: 1.571 ± 0.017	0.394TyrTrp: 0.394 ± 0.008	0.855TyrTyr: 0.855 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16484 proteins (6416465 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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