Amino acid dipepetide frequency for Punctularia strigosozonata (strain HHB-11173) (White-rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.312AlaAla: 10.312 ± 0.188
1.281AlaCys: 1.281 ± 0.045
4.871AlaAsp: 4.871 ± 0.077
5.209AlaGlu: 5.209 ± 0.099
3.74AlaPhe: 3.74 ± 0.087
6.154AlaGly: 6.154 ± 0.101
2.434AlaHis: 2.434 ± 0.059
4.414AlaIle: 4.414 ± 0.09
3.936AlaLys: 3.936 ± 0.094
9.208AlaLeu: 9.208 ± 0.151
1.979AlaMet: 1.979 ± 0.045
2.968AlaAsn: 2.968 ± 0.068
5.972AlaPro: 5.972 ± 0.124
3.632AlaGln: 3.632 ± 0.079
6.344AlaArg: 6.344 ± 0.098
8.356AlaSer: 8.356 ± 0.139
5.696AlaThr: 5.696 ± 0.101
6.141AlaVal: 6.141 ± 0.096
1.293AlaTrp: 1.293 ± 0.038
2.474AlaTyr: 2.474 ± 0.056
0.0AlaXaa: 0.0 ± 0.0
Cys
1.207CysAla: 1.207 ± 0.045
0.286CysCys: 0.286 ± 0.019
0.707CysAsp: 0.707 ± 0.031
0.645CysGlu: 0.645 ± 0.028
0.504CysPhe: 0.504 ± 0.026
1.003CysGly: 1.003 ± 0.036
0.375CysHis: 0.375 ± 0.023
0.639CysIle: 0.639 ± 0.031
0.467CysLys: 0.467 ± 0.024
1.399CysLeu: 1.399 ± 0.048
0.27CysMet: 0.27 ± 0.017
0.372CysAsn: 0.372 ± 0.021
0.822CysPro: 0.822 ± 0.038
0.454CysGln: 0.454 ± 0.025
0.843CysArg: 0.843 ± 0.032
1.052CysSer: 1.052 ± 0.041
0.764CysThr: 0.764 ± 0.033
0.826CysVal: 0.826 ± 0.036
0.217CysTrp: 0.217 ± 0.016
0.36CysTyr: 0.36 ± 0.022
0.0CysXaa: 0.0 ± 0.0
Asp
5.923AspAla: 5.923 ± 0.089
0.688AspCys: 0.688 ± 0.031
4.753AspAsp: 4.753 ± 0.114
4.523AspGlu: 4.523 ± 0.095
2.011AspPhe: 2.011 ± 0.046
4.522AspGly: 4.522 ± 0.075
1.352AspHis: 1.352 ± 0.046
2.797AspIle: 2.797 ± 0.058
1.966AspLys: 1.966 ± 0.054
5.109AspLeu: 5.109 ± 0.096
1.264AspMet: 1.264 ± 0.038
1.636AspAsn: 1.636 ± 0.043
3.765AspPro: 3.765 ± 0.065
1.657AspGln: 1.657 ± 0.044
3.167AspArg: 3.167 ± 0.077
3.771AspSer: 3.771 ± 0.083
3.039AspThr: 3.039 ± 0.067
4.466AspVal: 4.466 ± 0.077
0.995AspTrp: 0.995 ± 0.033
1.517AspTyr: 1.517 ± 0.045
0.0AspXaa: 0.0 ± 0.0
Glu
5.342GluAla: 5.342 ± 0.095
0.625GluCys: 0.625 ± 0.027
4.187GluAsp: 4.187 ± 0.101
5.333GluGlu: 5.333 ± 0.147
1.629GluPhe: 1.629 ± 0.05
3.748GluGly: 3.748 ± 0.082
1.447GluHis: 1.447 ± 0.042
2.628GluIle: 2.628 ± 0.065
2.838GluLys: 2.838 ± 0.083
5.079GluLeu: 5.079 ± 0.092
1.236GluMet: 1.236 ± 0.037
1.701GluAsn: 1.701 ± 0.05
2.882GluPro: 2.882 ± 0.084
2.273GluGln: 2.273 ± 0.056
4.359GluArg: 4.359 ± 0.089
3.563GluSer: 3.563 ± 0.065
2.983GluThr: 2.983 ± 0.066
3.542GluVal: 3.542 ± 0.083
0.93GluTrp: 0.93 ± 0.031
1.554GluTyr: 1.554 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
3.223PheAla: 3.223 ± 0.071
0.585PheCys: 0.585 ± 0.028
2.264PheAsp: 2.264 ± 0.05
1.807PheGlu: 1.807 ± 0.042
1.43PhePhe: 1.43 ± 0.055
2.804PheGly: 2.804 ± 0.073
0.866PheHis: 0.866 ± 0.035
1.593PheIle: 1.593 ± 0.046
1.379PheLys: 1.379 ± 0.036
3.11PheLeu: 3.11 ± 0.064
0.724PheMet: 0.724 ± 0.03
1.249PheAsn: 1.249 ± 0.043
2.012PhePro: 2.012 ± 0.056
1.054PheGln: 1.054 ± 0.035
1.944PheArg: 1.944 ± 0.049
2.828PheSer: 2.828 ± 0.071
2.065PheThr: 2.065 ± 0.048
2.447PheVal: 2.447 ± 0.058
0.601PheTrp: 0.601 ± 0.028
0.95PheTyr: 0.95 ± 0.031
0.0PheXaa: 0.0 ± 0.0
Gly
5.954GlyAla: 5.954 ± 0.11
0.986GlyCys: 0.986 ± 0.044
3.79GlyAsp: 3.79 ± 0.092
3.633GlyGlu: 3.633 ± 0.079
2.479GlyPhe: 2.479 ± 0.062
5.713GlyGly: 5.713 ± 0.145
1.946GlyHis: 1.946 ± 0.057
3.058GlyIle: 3.058 ± 0.07
3.05GlyLys: 3.05 ± 0.065
5.737GlyLeu: 5.737 ± 0.084
1.508GlyMet: 1.508 ± 0.05
2.289GlyAsn: 2.289 ± 0.055
3.693GlyPro: 3.693 ± 0.08
2.458GlyGln: 2.458 ± 0.056
4.275GlyArg: 4.275 ± 0.084
5.79GlySer: 5.79 ± 0.115
4.273GlyThr: 4.273 ± 0.072
4.596GlyVal: 4.596 ± 0.088
1.159GlyTrp: 1.159 ± 0.048
1.925GlyTyr: 1.925 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
2.601HisAla: 2.601 ± 0.053
0.339HisCys: 0.339 ± 0.019
1.555HisAsp: 1.555 ± 0.049
1.321HisGlu: 1.321 ± 0.041
0.929HisPhe: 0.929 ± 0.034
1.894HisGly: 1.894 ± 0.054
0.89HisHis: 0.89 ± 0.042
1.344HisIle: 1.344 ± 0.044
0.814HisLys: 0.814 ± 0.031
2.519HisLeu: 2.519 ± 0.07
0.491HisMet: 0.491 ± 0.024
0.829HisAsn: 0.829 ± 0.03
2.048HisPro: 2.048 ± 0.06
0.899HisGln: 0.899 ± 0.035
1.807HisArg: 1.807 ± 0.053
1.883HisSer: 1.883 ± 0.042
1.401HisThr: 1.401 ± 0.043
1.74HisVal: 1.74 ± 0.048
0.364HisTrp: 0.364 ± 0.023
0.67HisTyr: 0.67 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
4.411IleAla: 4.411 ± 0.068
0.717IleCys: 0.717 ± 0.031
2.668IleAsp: 2.668 ± 0.059
2.46IleGlu: 2.46 ± 0.052
1.584IlePhe: 1.584 ± 0.045
3.066IleGly: 3.066 ± 0.072
1.299IleHis: 1.299 ± 0.048
2.019IleIle: 2.019 ± 0.057
1.72IleLys: 1.72 ± 0.052
3.966IleLeu: 3.966 ± 0.08
0.873IleMet: 0.873 ± 0.034
1.328IleAsn: 1.328 ± 0.045
2.98IlePro: 2.98 ± 0.057
1.559IleGln: 1.559 ± 0.046
2.848IleArg: 2.848 ± 0.063
3.506IleSer: 3.506 ± 0.059
2.524IleThr: 2.524 ± 0.06
3.255IleVal: 3.255 ± 0.062
0.831IleTrp: 0.831 ± 0.033
1.22IleTyr: 1.22 ± 0.041
0.0IleXaa: 0.0 ± 0.0
Lys
3.937LysAla: 3.937 ± 0.094
0.492LysCys: 0.492 ± 0.026
2.267LysAsp: 2.267 ± 0.058
2.72LysGlu: 2.72 ± 0.08
1.115LysPhe: 1.115 ± 0.04
2.658LysGly: 2.658 ± 0.071
1.061LysHis: 1.061 ± 0.035
1.762LysIle: 1.762 ± 0.052
2.533LysLys: 2.533 ± 0.109
3.521LysLeu: 3.521 ± 0.085
0.767LysMet: 0.767 ± 0.028
1.267LysAsn: 1.267 ± 0.041
2.419LysPro: 2.419 ± 0.065
1.403LysGln: 1.403 ± 0.046
3.185LysArg: 3.185 ± 0.067
2.612LysSer: 2.612 ± 0.061
2.462LysThr: 2.462 ± 0.06
2.387LysVal: 2.387 ± 0.06
0.59LysTrp: 0.59 ± 0.025
1.126LysTyr: 1.126 ± 0.038
0.0LysXaa: 0.0 ± 0.0
Leu
8.895LeuAla: 8.895 ± 0.122
1.354LeuCys: 1.354 ± 0.047
5.252LeuAsp: 5.252 ± 0.086
5.243LeuGlu: 5.243 ± 0.096
3.028LeuPhe: 3.028 ± 0.064
5.891LeuGly: 5.891 ± 0.104
2.495LeuHis: 2.495 ± 0.06
3.473LeuIle: 3.473 ± 0.083
3.58LeuLys: 3.58 ± 0.07
8.431LeuLeu: 8.431 ± 0.13
1.627LeuMet: 1.627 ± 0.047
2.814LeuAsn: 2.814 ± 0.061
6.198LeuPro: 6.198 ± 0.103
3.442LeuGln: 3.442 ± 0.072
6.489LeuArg: 6.489 ± 0.125
7.275LeuSer: 7.275 ± 0.098
4.831LeuThr: 4.831 ± 0.074
5.815LeuVal: 5.815 ± 0.111
1.438LeuTrp: 1.438 ± 0.044
2.228LeuTyr: 2.228 ± 0.059
0.0LeuXaa: 0.0 ± 0.0
Met
1.883MetAla: 1.883 ± 0.05
0.239MetCys: 0.239 ± 0.015
1.185MetAsp: 1.185 ± 0.039
1.117MetGlu: 1.117 ± 0.037
0.781MetPhe: 0.781 ± 0.035
1.223MetGly: 1.223 ± 0.04
0.565MetHis: 0.565 ± 0.028
0.856MetIle: 0.856 ± 0.028
0.862MetLys: 0.862 ± 0.03
1.852MetLeu: 1.852 ± 0.047
0.482MetMet: 0.482 ± 0.026
0.658MetAsn: 0.658 ± 0.026
1.374MetPro: 1.374 ± 0.041
0.885MetGln: 0.885 ± 0.037
1.429MetArg: 1.429 ± 0.04
1.695MetSer: 1.695 ± 0.049
1.143MetThr: 1.143 ± 0.032
1.133MetVal: 1.133 ± 0.036
0.247MetTrp: 0.247 ± 0.022
0.466MetTyr: 0.466 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
3.266AsnAla: 3.266 ± 0.063
0.398AsnCys: 0.398 ± 0.027
1.818AsnAsp: 1.818 ± 0.043
1.635AsnGlu: 1.635 ± 0.041
1.132AsnPhe: 1.132 ± 0.037
2.65AsnGly: 2.65 ± 0.067
0.743AsnHis: 0.743 ± 0.026
1.666AsnIle: 1.666 ± 0.045
1.073AsnLys: 1.073 ± 0.034
2.76AsnLeu: 2.76 ± 0.064
0.684AsnMet: 0.684 ± 0.031
1.109AsnAsn: 1.109 ± 0.058
2.122AsnPro: 2.122 ± 0.054
0.951AsnGln: 0.951 ± 0.036
1.651AsnArg: 1.651 ± 0.043
2.201AsnSer: 2.201 ± 0.058
1.923AsnThr: 1.923 ± 0.046
2.328AsnVal: 2.328 ± 0.06
0.51AsnTrp: 0.51 ± 0.022
0.857AsnTyr: 0.857 ± 0.033
0.0AsnXaa: 0.0 ± 0.0
Pro
6.525ProAla: 6.525 ± 0.146
0.646ProCys: 0.646 ± 0.034
3.796ProAsp: 3.796 ± 0.082
3.75ProGlu: 3.75 ± 0.072
2.181ProPhe: 2.181 ± 0.059
4.135ProGly: 4.135 ± 0.084
1.619ProHis: 1.619 ± 0.048
2.549ProIle: 2.549 ± 0.052
2.271ProLys: 2.271 ± 0.066
5.471ProLeu: 5.471 ± 0.084
1.039ProMet: 1.039 ± 0.034
2.132ProAsn: 2.132 ± 0.06
6.498ProPro: 6.498 ± 0.189
2.297ProGln: 2.297 ± 0.056
4.05ProArg: 4.05 ± 0.086
6.958ProSer: 6.958 ± 0.137
4.415ProThr: 4.415 ± 0.083
4.082ProVal: 4.082 ± 0.08
0.871ProTrp: 0.871 ± 0.038
1.573ProTyr: 1.573 ± 0.06
0.0ProXaa: 0.0 ± 0.0
Gln
3.456GlnAla: 3.456 ± 0.081
0.47GlnCys: 0.47 ± 0.025
1.934GlnAsp: 1.934 ± 0.049
1.99GlnGlu: 1.99 ± 0.06
1.108GlnPhe: 1.108 ± 0.037
2.269GlnGly: 2.269 ± 0.056
1.073GlnHis: 1.073 ± 0.049
1.583GlnIle: 1.583 ± 0.044
1.424GlnLys: 1.424 ± 0.044
3.246GlnLeu: 3.246 ± 0.077
0.763GlnMet: 0.763 ± 0.027
1.178GlnAsn: 1.178 ± 0.038
2.414GlnPro: 2.414 ± 0.071
1.906GlnGln: 1.906 ± 0.105
2.608GlnArg: 2.608 ± 0.058
2.693GlnSer: 2.693 ± 0.059
2.118GlnThr: 2.118 ± 0.062
2.021GlnVal: 2.021 ± 0.054
0.59GlnTrp: 0.59 ± 0.029
0.958GlnTyr: 0.958 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
6.187ArgAla: 6.187 ± 0.107
0.876ArgCys: 0.876 ± 0.036
3.444ArgAsp: 3.444 ± 0.072
3.916ArgGlu: 3.916 ± 0.081
2.184ArgPhe: 2.184 ± 0.055
3.778ArgGly: 3.778 ± 0.069
1.806ArgHis: 1.806 ± 0.05
3.069ArgIle: 3.069 ± 0.066
3.1ArgLys: 3.1 ± 0.077
6.066ArgLeu: 6.066 ± 0.103
1.397ArgMet: 1.397 ± 0.053
1.967ArgAsn: 1.967 ± 0.05
4.133ArgPro: 4.133 ± 0.081
2.533ArgGln: 2.533 ± 0.062
5.752ArgArg: 5.752 ± 0.114
5.256ArgSer: 5.256 ± 0.092
3.903ArgThr: 3.903 ± 0.083
3.751ArgVal: 3.751 ± 0.077
1.218ArgTrp: 1.218 ± 0.041
1.687ArgTyr: 1.687 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
7.784SerAla: 7.784 ± 0.135
0.92SerCys: 0.92 ± 0.035
4.651SerAsp: 4.651 ± 0.098
3.856SerGlu: 3.856 ± 0.071
2.668SerPhe: 2.668 ± 0.062
5.791SerGly: 5.791 ± 0.101
1.908SerHis: 1.908 ± 0.047
3.542SerIle: 3.542 ± 0.083
2.882SerLys: 2.882 ± 0.067
7.048SerLeu: 7.048 ± 0.101
1.574SerMet: 1.574 ± 0.05
2.443SerAsn: 2.443 ± 0.058
6.102SerPro: 6.102 ± 0.134
2.667SerGln: 2.667 ± 0.075
4.974SerArg: 4.974 ± 0.089
9.344SerSer: 9.344 ± 0.218
5.932SerThr: 5.932 ± 0.132
5.105SerVal: 5.105 ± 0.074
1.06SerTrp: 1.06 ± 0.034
1.921SerTyr: 1.921 ± 0.052
0.0SerXaa: 0.0 ± 0.0
Thr
5.527ThrAla: 5.527 ± 0.091
0.808ThrCys: 0.808 ± 0.036
3.006ThrAsp: 3.006 ± 0.065
2.637ThrGlu: 2.637 ± 0.061
2.338ThrPhe: 2.338 ± 0.048
4.172ThrGly: 4.172 ± 0.082
1.547ThrHis: 1.547 ± 0.045
2.925ThrIle: 2.925 ± 0.063
2.184ThrLys: 2.184 ± 0.052
5.472ThrLeu: 5.472 ± 0.096
1.192ThrMet: 1.192 ± 0.037
1.863ThrAsn: 1.863 ± 0.051
4.633ThrPro: 4.633 ± 0.108
1.863ThrGln: 1.863 ± 0.048
3.586ThrArg: 3.586 ± 0.072
5.557ThrSer: 5.557 ± 0.121
4.195ThrThr: 4.195 ± 0.109
4.03ThrVal: 4.03 ± 0.082
0.865ThrTrp: 0.865 ± 0.038
1.485ThrTyr: 1.485 ± 0.043
0.0ThrXaa: 0.0 ± 0.0
Val
6.2ValAla: 6.2 ± 0.11
0.86ValCys: 0.86 ± 0.035
4.077ValAsp: 4.077 ± 0.083
3.813ValGlu: 3.813 ± 0.068
2.542ValPhe: 2.542 ± 0.059
4.085ValGly: 4.085 ± 0.085
1.817ValHis: 1.817 ± 0.054
2.817ValIle: 2.817 ± 0.063
2.58ValLys: 2.58 ± 0.067
6.096ValLeu: 6.096 ± 0.097
1.207ValMet: 1.207 ± 0.036
2.161ValAsn: 2.161 ± 0.057
4.456ValPro: 4.456 ± 0.086
2.443ValGln: 2.443 ± 0.05
3.996ValArg: 3.996 ± 0.073
4.832ValSer: 4.832 ± 0.08
3.667ValThr: 3.667 ± 0.067
4.986ValVal: 4.986 ± 0.101
0.936ValTrp: 0.936 ± 0.035
1.795ValTyr: 1.795 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
1.261TrpAla: 1.261 ± 0.044
0.253TrpCys: 0.253 ± 0.018
1.08TrpAsp: 1.08 ± 0.047
0.857TrpGlu: 0.857 ± 0.031
0.585TrpPhe: 0.585 ± 0.027
0.897TrpGly: 0.897 ± 0.032
0.394TrpHis: 0.394 ± 0.024
0.797TrpIle: 0.797 ± 0.033
0.747TrpLys: 0.747 ± 0.029
1.385TrpLeu: 1.385 ± 0.041
0.4TrpMet: 0.4 ± 0.024
0.572TrpAsn: 0.572 ± 0.028
0.728TrpPro: 0.728 ± 0.03
0.541TrpGln: 0.541 ± 0.025
1.039TrpArg: 1.039 ± 0.039
1.166TrpSer: 1.166 ± 0.041
1.075TrpThr: 1.075 ± 0.038
0.899TrpVal: 0.899 ± 0.036
0.311TrpTrp: 0.311 ± 0.022
0.453TrpTyr: 0.453 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.518TyrAla: 2.518 ± 0.049
0.387TyrCys: 0.387 ± 0.024
1.616TyrAsp: 1.616 ± 0.051
1.415TyrGlu: 1.415 ± 0.049
0.965TyrPhe: 0.965 ± 0.035
1.86TyrGly: 1.86 ± 0.053
0.702TyrHis: 0.702 ± 0.031
1.307TyrIle: 1.307 ± 0.036
0.875TyrLys: 0.875 ± 0.036
2.323TyrLeu: 2.323 ± 0.052
0.597TyrMet: 0.597 ± 0.032
0.94TyrAsn: 0.94 ± 0.03
1.604TyrPro: 1.604 ± 0.051
0.887TyrGln: 0.887 ± 0.031
1.678TyrArg: 1.678 ± 0.041
1.833TyrSer: 1.833 ± 0.051
1.478TyrThr: 1.478 ± 0.043
1.819TyrVal: 1.819 ± 0.052
0.414TyrTrp: 0.414 ± 0.024
0.759TyrTyr: 0.759 ± 0.034
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2093 proteins (867311 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski