Amino acid dipepetide frequency for Candidatus Termititenax dinenymphae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.026AlaAla: 8.026 ± 0.329
0.757AlaCys: 0.757 ± 0.1
5.366AlaAsp: 5.366 ± 0.234
6.659AlaGlu: 6.659 ± 0.326
2.614AlaPhe: 2.614 ± 0.159
6.373AlaGly: 6.373 ± 0.281
1.173AlaHis: 1.173 ± 0.113
4.674AlaIle: 4.674 ± 0.234
5.726AlaLys: 5.726 ± 0.311
7.879AlaLeu: 7.879 ± 0.309
1.45AlaMet: 1.45 ± 0.121
3.297AlaAsn: 3.297 ± 0.206
2.272AlaPro: 2.272 ± 0.182
3.491AlaGln: 3.491 ± 0.202
3.667AlaArg: 3.667 ± 0.217
4.119AlaSer: 4.119 ± 0.206
3.103AlaThr: 3.103 ± 0.192
6.465AlaVal: 6.465 ± 0.256
0.739AlaTrp: 0.739 ± 0.076
2.872AlaTyr: 2.872 ± 0.17
0.0AlaXaa: 0.0 ± 0.0
Cys
0.683CysAla: 0.683 ± 0.077
0.074CysCys: 0.074 ± 0.025
0.342CysAsp: 0.342 ± 0.058
0.434CysGlu: 0.434 ± 0.067
0.416CysPhe: 0.416 ± 0.068
0.85CysGly: 0.85 ± 0.103
0.212CysHis: 0.212 ± 0.048
0.61CysIle: 0.61 ± 0.087
0.397CysLys: 0.397 ± 0.061
1.108CysLeu: 1.108 ± 0.118
0.102CysMet: 0.102 ± 0.03
0.342CysAsn: 0.342 ± 0.062
0.379CysPro: 0.379 ± 0.067
0.333CysGln: 0.333 ± 0.051
0.425CysArg: 0.425 ± 0.061
0.379CysSer: 0.379 ± 0.066
0.434CysThr: 0.434 ± 0.073
0.49CysVal: 0.49 ± 0.08
0.074CysTrp: 0.074 ± 0.025
0.268CysTyr: 0.268 ± 0.047
0.0CysXaa: 0.0 ± 0.0
Asp
4.11AspAla: 4.11 ± 0.201
0.656AspCys: 0.656 ± 0.079
2.577AspAsp: 2.577 ± 0.174
3.039AspGlu: 3.039 ± 0.198
2.983AspPhe: 2.983 ± 0.151
3.768AspGly: 3.768 ± 0.243
0.831AspHis: 0.831 ± 0.084
4.507AspIle: 4.507 ± 0.191
4.572AspLys: 4.572 ± 0.282
6.087AspLeu: 6.087 ± 0.232
1.136AspMet: 1.136 ± 0.118
3.039AspAsn: 3.039 ± 0.181
2.226AspPro: 2.226 ± 0.147
1.82AspGln: 1.82 ± 0.16
2.3AspArg: 2.3 ± 0.15
3.482AspSer: 3.482 ± 0.235
3.288AspThr: 3.288 ± 0.18
3.898AspVal: 3.898 ± 0.222
0.536AspTrp: 0.536 ± 0.074
2.614AspTyr: 2.614 ± 0.18
0.0AspXaa: 0.0 ± 0.0
Glu
4.646GluAla: 4.646 ± 0.261
0.369GluCys: 0.369 ± 0.053
2.836GluAsp: 2.836 ± 0.171
3.972GluGlu: 3.972 ± 0.258
2.466GluPhe: 2.466 ± 0.186
2.919GluGly: 2.919 ± 0.186
1.312GluHis: 1.312 ± 0.116
5.634GluIle: 5.634 ± 0.259
5.81GluLys: 5.81 ± 0.301
6.964GluLeu: 6.964 ± 0.311
1.441GluMet: 1.441 ± 0.109
3.768GluAsn: 3.768 ± 0.194
1.699GluPro: 1.699 ± 0.134
3.196GluGln: 3.196 ± 0.191
2.836GluArg: 2.836 ± 0.187
2.863GluSer: 2.863 ± 0.176
3.824GluThr: 3.824 ± 0.199
3.556GluVal: 3.556 ± 0.183
0.434GluTrp: 0.434 ± 0.052
3.113GluTyr: 3.113 ± 0.215
0.0GluXaa: 0.0 ± 0.0
Phe
3.159PheAla: 3.159 ± 0.179
0.563PheCys: 0.563 ± 0.069
2.503PheAsp: 2.503 ± 0.153
2.06PheGlu: 2.06 ± 0.15
1.727PhePhe: 1.727 ± 0.183
3.029PheGly: 3.029 ± 0.173
0.619PheHis: 0.619 ± 0.083
2.466PheIle: 2.466 ± 0.137
2.309PheLys: 2.309 ± 0.174
4.129PheLeu: 4.129 ± 0.259
0.877PheMet: 0.877 ± 0.091
2.106PheAsn: 2.106 ± 0.159
1.469PhePro: 1.469 ± 0.134
1.644PheGln: 1.644 ± 0.134
1.635PheArg: 1.635 ± 0.148
2.956PheSer: 2.956 ± 0.181
2.549PheThr: 2.549 ± 0.18
2.549PheVal: 2.549 ± 0.147
0.48PheTrp: 0.48 ± 0.063
1.755PheTyr: 1.755 ± 0.162
0.0PheXaa: 0.0 ± 0.0
Gly
4.563GlyAla: 4.563 ± 0.225
0.776GlyCys: 0.776 ± 0.102
3.288GlyAsp: 3.288 ± 0.21
3.621GlyGlu: 3.621 ± 0.182
3.187GlyPhe: 3.187 ± 0.18
5.191GlyGly: 5.191 ± 0.329
1.275GlyHis: 1.275 ± 0.101
5.117GlyIle: 5.117 ± 0.228
4.877GlyLys: 4.877 ± 0.181
6.659GlyLeu: 6.659 ± 0.273
1.607GlyMet: 1.607 ± 0.144
3.066GlyAsn: 3.066 ± 0.266
1.302GlyPro: 1.302 ± 0.117
2.993GlyGln: 2.993 ± 0.184
3.454GlyArg: 3.454 ± 0.198
4.415GlySer: 4.415 ± 0.234
3.981GlyThr: 3.981 ± 0.186
4.452GlyVal: 4.452 ± 0.249
0.739GlyTrp: 0.739 ± 0.095
2.669GlyTyr: 2.669 ± 0.156
0.0GlyXaa: 0.0 ± 0.0
His
0.998HisAla: 0.998 ± 0.11
0.222HisCys: 0.222 ± 0.045
0.831HisAsp: 0.831 ± 0.095
0.84HisGlu: 0.84 ± 0.094
0.748HisPhe: 0.748 ± 0.081
1.367HisGly: 1.367 ± 0.11
0.323HisHis: 0.323 ± 0.061
1.395HisIle: 1.395 ± 0.121
1.034HisLys: 1.034 ± 0.115
1.626HisLeu: 1.626 ± 0.136
0.259HisMet: 0.259 ± 0.046
1.062HisAsn: 1.062 ± 0.106
0.887HisPro: 0.887 ± 0.086
0.656HisGln: 0.656 ± 0.082
0.711HisArg: 0.711 ± 0.082
0.979HisSer: 0.979 ± 0.09
1.016HisThr: 1.016 ± 0.108
0.896HisVal: 0.896 ± 0.09
0.222HisTrp: 0.222 ± 0.048
0.85HisTyr: 0.85 ± 0.095
0.0HisXaa: 0.0 ± 0.0
Ile
6.253IleAla: 6.253 ± 0.235
0.582IleCys: 0.582 ± 0.072
4.637IleAsp: 4.637 ± 0.214
4.258IleGlu: 4.258 ± 0.19
3.187IlePhe: 3.187 ± 0.187
4.369IleGly: 4.369 ± 0.236
1.071IleHis: 1.071 ± 0.104
5.154IleIle: 5.154 ± 0.218
5.025IleLys: 5.025 ± 0.234
6.401IleLeu: 6.401 ± 0.282
1.413IleMet: 1.413 ± 0.091
3.815IleAsn: 3.815 ± 0.21
2.872IlePro: 2.872 ± 0.142
2.189IleGln: 2.189 ± 0.183
3.029IleArg: 3.029 ± 0.156
4.766IleSer: 4.766 ± 0.222
4.526IleThr: 4.526 ± 0.216
4.71IleVal: 4.71 ± 0.26
0.517IleTrp: 0.517 ± 0.073
2.743IleTyr: 2.743 ± 0.174
0.0IleXaa: 0.0 ± 0.0
Lys
5.283LysAla: 5.283 ± 0.231
0.36LysCys: 0.36 ± 0.067
4.563LysAsp: 4.563 ± 0.259
4.988LysGlu: 4.988 ± 0.255
2.244LysPhe: 2.244 ± 0.146
3.464LysGly: 3.464 ± 0.207
1.21LysHis: 1.21 ± 0.118
6.752LysIle: 6.752 ± 0.302
6.207LysLys: 6.207 ± 0.346
6.872LysLeu: 6.872 ± 0.262
1.718LysMet: 1.718 ± 0.137
4.23LysAsn: 4.23 ± 0.252
2.549LysPro: 2.549 ± 0.149
2.845LysGln: 2.845 ± 0.166
2.521LysArg: 2.521 ± 0.144
3.187LysSer: 3.187 ± 0.194
4.812LysThr: 4.812 ± 0.232
4.073LysVal: 4.073 ± 0.162
0.351LysTrp: 0.351 ± 0.057
3.417LysTyr: 3.417 ± 0.205
0.0LysXaa: 0.0 ± 0.0
Leu
8.331LeuAla: 8.331 ± 0.363
0.776LeuCys: 0.776 ± 0.099
6.142LeuAsp: 6.142 ± 0.219
6.53LeuGlu: 6.53 ± 0.315
3.584LeuPhe: 3.584 ± 0.189
6.521LeuGly: 6.521 ± 0.344
1.709LeuHis: 1.709 ± 0.146
6.022LeuIle: 6.022 ± 0.221
7.01LeuLys: 7.01 ± 0.311
9.467LeuLeu: 9.467 ± 0.346
1.727LeuMet: 1.727 ± 0.14
5.098LeuAsn: 5.098 ± 0.22
4.304LeuPro: 4.304 ± 0.193
4.415LeuGln: 4.415 ± 0.266
5.366LeuArg: 5.366 ± 0.253
6.595LeuSer: 6.595 ± 0.277
5.93LeuThr: 5.93 ± 0.256
5.246LeuVal: 5.246 ± 0.252
0.711LeuTrp: 0.711 ± 0.086
3.501LeuTyr: 3.501 ± 0.196
0.0LeuXaa: 0.0 ± 0.0
Met
1.616MetAla: 1.616 ± 0.109
0.102MetCys: 0.102 ± 0.027
1.145MetAsp: 1.145 ± 0.093
1.034MetGlu: 1.034 ± 0.13
0.831MetPhe: 0.831 ± 0.09
1.182MetGly: 1.182 ± 0.114
0.443MetHis: 0.443 ± 0.059
1.127MetIle: 1.127 ± 0.134
1.062MetLys: 1.062 ± 0.118
2.161MetLeu: 2.161 ± 0.116
0.369MetMet: 0.369 ± 0.066
0.813MetAsn: 0.813 ± 0.078
1.173MetPro: 1.173 ± 0.11
0.896MetGln: 0.896 ± 0.096
1.118MetArg: 1.118 ± 0.104
1.293MetSer: 1.293 ± 0.116
1.21MetThr: 1.21 ± 0.105
1.321MetVal: 1.321 ± 0.118
0.111MetTrp: 0.111 ± 0.038
0.748MetTyr: 0.748 ± 0.093
0.0MetXaa: 0.0 ± 0.0
Asn
3.815AsnAla: 3.815 ± 0.212
0.425AsnCys: 0.425 ± 0.064
2.383AsnAsp: 2.383 ± 0.183
2.364AsnGlu: 2.364 ± 0.167
2.217AsnPhe: 2.217 ± 0.135
3.602AsnGly: 3.602 ± 0.237
0.628AsnHis: 0.628 ± 0.075
4.406AsnIle: 4.406 ± 0.23
4.027AsnLys: 4.027 ± 0.216
4.526AsnLeu: 4.526 ± 0.229
1.071AsnMet: 1.071 ± 0.082
3.159AsnAsn: 3.159 ± 0.194
2.568AsnPro: 2.568 ± 0.149
1.413AsnGln: 1.413 ± 0.117
2.004AsnArg: 2.004 ± 0.13
3.02AsnSer: 3.02 ± 0.188
2.836AsnThr: 2.836 ± 0.221
2.882AsnVal: 2.882 ± 0.164
0.536AsnTrp: 0.536 ± 0.079
2.383AsnTyr: 2.383 ± 0.175
0.0AsnXaa: 0.0 ± 0.0
Pro
3.39ProAla: 3.39 ± 0.185
0.194ProCys: 0.194 ± 0.045
2.734ProAsp: 2.734 ± 0.157
3.75ProGlu: 3.75 ± 0.182
1.376ProPhe: 1.376 ± 0.1
2.605ProGly: 2.605 ± 0.167
0.757ProHis: 0.757 ± 0.099
1.94ProIle: 1.94 ± 0.152
2.004ProLys: 2.004 ± 0.125
3.639ProLeu: 3.639 ± 0.183
0.563ProMet: 0.563 ± 0.073
1.459ProAsn: 1.459 ± 0.115
1.422ProPro: 1.422 ± 0.147
1.903ProGln: 1.903 ± 0.143
1.616ProArg: 1.616 ± 0.124
1.755ProSer: 1.755 ± 0.118
1.829ProThr: 1.829 ± 0.155
3.039ProVal: 3.039 ± 0.184
0.333ProTrp: 0.333 ± 0.067
1.275ProTyr: 1.275 ± 0.118
0.0ProXaa: 0.0 ± 0.0
Gln
3.159GlnAla: 3.159 ± 0.195
0.249GlnCys: 0.249 ± 0.053
2.171GlnAsp: 2.171 ± 0.143
3.048GlnGlu: 3.048 ± 0.22
1.228GlnPhe: 1.228 ± 0.114
2.041GlnGly: 2.041 ± 0.152
0.767GlnHis: 0.767 ± 0.082
3.38GlnIle: 3.38 ± 0.178
4.073GlnLys: 4.073 ± 0.261
3.251GlnLeu: 3.251 ± 0.202
0.942GlnMet: 0.942 ± 0.098
2.3GlnAsn: 2.3 ± 0.156
1.422GlnPro: 1.422 ± 0.12
1.663GlnGln: 1.663 ± 0.161
2.004GlnArg: 2.004 ± 0.163
2.171GlnSer: 2.171 ± 0.131
2.364GlnThr: 2.364 ± 0.177
2.254GlnVal: 2.254 ± 0.149
0.286GlnTrp: 0.286 ± 0.054
1.681GlnTyr: 1.681 ± 0.131
0.0GlnXaa: 0.0 ± 0.0
Arg
3.15ArgAla: 3.15 ± 0.153
0.277ArgCys: 0.277 ± 0.055
2.392ArgAsp: 2.392 ± 0.148
3.519ArgGlu: 3.519 ± 0.21
1.921ArgPhe: 1.921 ± 0.139
2.632ArgGly: 2.632 ± 0.18
0.748ArgHis: 0.748 ± 0.081
3.464ArgIle: 3.464 ± 0.194
3.26ArgLys: 3.26 ± 0.2
4.988ArgLeu: 4.988 ± 0.24
0.933ArgMet: 0.933 ± 0.096
2.392ArgAsn: 2.392 ± 0.144
1.552ArgPro: 1.552 ± 0.129
2.023ArgGln: 2.023 ± 0.162
2.244ArgArg: 2.244 ± 0.187
2.78ArgSer: 2.78 ± 0.166
2.171ArgThr: 2.171 ± 0.14
2.642ArgVal: 2.642 ± 0.17
0.462ArgTrp: 0.462 ± 0.065
1.727ArgTyr: 1.727 ± 0.134
0.0ArgXaa: 0.0 ± 0.0
Ser
5.726SerAla: 5.726 ± 0.258
0.425SerCys: 0.425 ± 0.075
3.076SerAsp: 3.076 ± 0.205
3.464SerGlu: 3.464 ± 0.195
2.355SerPhe: 2.355 ± 0.176
5.957SerGly: 5.957 ± 0.337
0.739SerHis: 0.739 ± 0.082
3.796SerIle: 3.796 ± 0.154
3.621SerLys: 3.621 ± 0.21
5.8SerLeu: 5.8 ± 0.281
0.988SerMet: 0.988 ± 0.107
2.337SerAsn: 2.337 ± 0.183
2.152SerPro: 2.152 ± 0.136
1.773SerGln: 1.773 ± 0.143
2.577SerArg: 2.577 ± 0.163
3.38SerSer: 3.38 ± 0.211
3.445SerThr: 3.445 ± 0.203
4.092SerVal: 4.092 ± 0.196
0.6SerTrp: 0.6 ± 0.087
2.346SerTyr: 2.346 ± 0.195
0.0SerXaa: 0.0 ± 0.0
Thr
5.459ThrAla: 5.459 ± 0.245
0.36ThrCys: 0.36 ± 0.058
3.621ThrAsp: 3.621 ± 0.188
3.454ThrGlu: 3.454 ± 0.206
2.115ThrPhe: 2.115 ± 0.159
4.72ThrGly: 4.72 ± 0.222
0.988ThrHis: 0.988 ± 0.108
3.962ThrIle: 3.962 ± 0.215
3.602ThrLys: 3.602 ± 0.22
5.477ThrLeu: 5.477 ± 0.215
0.979ThrMet: 0.979 ± 0.092
2.309ThrAsn: 2.309 ± 0.166
2.466ThrPro: 2.466 ± 0.155
2.198ThrGln: 2.198 ± 0.147
2.124ThrArg: 2.124 ± 0.141
2.993ThrSer: 2.993 ± 0.165
3.501ThrThr: 3.501 ± 0.193
4.563ThrVal: 4.563 ± 0.286
0.406ThrTrp: 0.406 ± 0.055
1.986ThrTyr: 1.986 ± 0.162
0.0ThrXaa: 0.0 ± 0.0
Val
4.655ValAla: 4.655 ± 0.258
0.693ValCys: 0.693 ± 0.081
3.722ValAsp: 3.722 ± 0.219
3.907ValGlu: 3.907 ± 0.186
2.974ValPhe: 2.974 ± 0.208
3.436ValGly: 3.436 ± 0.243
1.099ValHis: 1.099 ± 0.099
4.276ValIle: 4.276 ± 0.205
4.018ValLys: 4.018 ± 0.181
6.946ValLeu: 6.946 ± 0.242
1.312ValMet: 1.312 ± 0.123
3.159ValAsn: 3.159 ± 0.231
2.715ValPro: 2.715 ± 0.19
2.485ValGln: 2.485 ± 0.155
3.26ValArg: 3.26 ± 0.191
4.526ValSer: 4.526 ± 0.251
3.454ValThr: 3.454 ± 0.219
4.729ValVal: 4.729 ± 0.224
0.563ValTrp: 0.563 ± 0.081
2.448ValTyr: 2.448 ± 0.153
0.0ValXaa: 0.0 ± 0.0
Trp
0.526TrpAla: 0.526 ± 0.067
0.065TrpCys: 0.065 ± 0.025
0.536TrpAsp: 0.536 ± 0.071
0.443TrpGlu: 0.443 ± 0.068
0.323TrpPhe: 0.323 ± 0.052
0.499TrpGly: 0.499 ± 0.063
0.148TrpHis: 0.148 ± 0.041
0.573TrpIle: 0.573 ± 0.072
0.508TrpLys: 0.508 ± 0.086
1.062TrpLeu: 1.062 ± 0.109
0.166TrpMet: 0.166 ± 0.041
0.425TrpAsn: 0.425 ± 0.062
0.305TrpPro: 0.305 ± 0.062
0.573TrpGln: 0.573 ± 0.086
0.554TrpArg: 0.554 ± 0.067
0.573TrpSer: 0.573 ± 0.079
0.49TrpThr: 0.49 ± 0.089
0.342TrpVal: 0.342 ± 0.061
0.102TrpTrp: 0.102 ± 0.029
0.333TrpTyr: 0.333 ± 0.055
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.177TyrAla: 3.177 ± 0.197
0.425TyrCys: 0.425 ± 0.063
2.605TyrAsp: 2.605 ± 0.224
2.272TyrGlu: 2.272 ± 0.147
2.087TyrPhe: 2.087 ± 0.147
2.706TyrGly: 2.706 ± 0.161
0.868TyrHis: 0.868 ± 0.073
2.263TyrIle: 2.263 ± 0.156
2.503TyrLys: 2.503 ± 0.165
3.953TyrLeu: 3.953 ± 0.191
0.693TyrMet: 0.693 ± 0.095
2.087TyrAsn: 2.087 ± 0.172
1.847TyrPro: 1.847 ± 0.152
1.949TyrGln: 1.949 ± 0.129
1.829TyrArg: 1.829 ± 0.151
2.42TyrSer: 2.42 ± 0.164
2.521TyrThr: 2.521 ± 0.171
2.18TyrVal: 2.18 ± 0.173
0.342TyrTrp: 0.342 ± 0.055
2.004TyrTyr: 2.004 ± 0.206
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 355 proteins (108270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski