Amino acid dipepetide frequency for Temnothorax longispinosus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.792AlaAla: 5.792 ± 0.062	1.302AlaCys: 1.302 ± 0.029	3.155AlaAsp: 3.155 ± 0.026	4.111AlaGlu: 4.111 ± 0.033	2.17AlaPhe: 2.17 ± 0.021	3.664AlaGly: 3.664 ± 0.038	1.45AlaHis: 1.45 ± 0.018	3.683AlaIle: 3.683 ± 0.026	3.779AlaLys: 3.779 ± 0.041	5.821AlaLeu: 5.821 ± 0.05	1.514AlaMet: 1.514 ± 0.016	2.821AlaAsn: 2.821 ± 0.023	2.9AlaPro: 2.9 ± 0.029	2.4AlaGln: 2.4 ± 0.023	4.219AlaArg: 4.219 ± 0.037	5.199AlaSer: 5.199 ± 0.037	4.265AlaThr: 4.265 ± 0.032	4.237AlaVal: 4.237 ± 0.034	0.653AlaTrp: 0.653 ± 0.011	1.691AlaTyr: 1.691 ± 0.017	0.015AlaXaa: 0.015 ± 0.001
Cys	1.233CysAla: 1.233 ± 0.018	0.512CysCys: 0.512 ± 0.011	1.146CysAsp: 1.146 ± 0.023	1.171CysGlu: 1.171 ± 0.023	0.727CysPhe: 0.727 ± 0.012	1.373CysGly: 1.373 ± 0.044	0.54CysHis: 0.54 ± 0.013	1.176CysIle: 1.176 ± 0.028	1.198CysLys: 1.198 ± 0.021	1.822CysLeu: 1.822 ± 0.029	0.407CysMet: 0.407 ± 0.009	1.005CysAsn: 1.005 ± 0.02	1.075CysPro: 1.075 ± 0.04	0.779CysGln: 0.779 ± 0.021	1.294CysArg: 1.294 ± 0.038	1.589CysSer: 1.589 ± 0.036	1.195CysThr: 1.195 ± 0.027	1.273CysVal: 1.273 ± 0.032	0.239CysTrp: 0.239 ± 0.008	0.604CysTyr: 0.604 ± 0.013	0.006CysXaa: 0.006 ± 0.001
Asp	3.333AspAla: 3.333 ± 0.027	1.017AspCys: 1.017 ± 0.023	3.798AspAsp: 3.798 ± 0.041	4.183AspGlu: 4.183 ± 0.037	1.999AspPhe: 1.999 ± 0.018	3.147AspGly: 3.147 ± 0.028	1.138AspHis: 1.138 ± 0.014	3.486AspIle: 3.486 ± 0.028	3.319AspLys: 3.319 ± 0.032	4.672AspLeu: 4.672 ± 0.036	1.215AspMet: 1.215 ± 0.015	2.723AspAsn: 2.723 ± 0.027	2.413AspPro: 2.413 ± 0.036	1.649AspGln: 1.649 ± 0.015	3.015AspArg: 3.015 ± 0.031	4.25AspSer: 4.25 ± 0.033	3.07AspThr: 3.07 ± 0.027	3.763AspVal: 3.763 ± 0.029	0.608AspTrp: 0.608 ± 0.012	1.758AspTyr: 1.758 ± 0.019	0.017AspXaa: 0.017 ± 0.002
Glu	4.024GluAla: 4.024 ± 0.034	1.224GluCys: 1.224 ± 0.044	4.075GluAsp: 4.075 ± 0.033	6.282GluGlu: 6.282 ± 0.065	2.034GluPhe: 2.034 ± 0.019	3.027GluGly: 3.027 ± 0.03	1.505GluHis: 1.505 ± 0.016	4.068GluIle: 4.068 ± 0.034	5.132GluLys: 5.132 ± 0.056	5.537GluLeu: 5.537 ± 0.044	1.606GluMet: 1.606 ± 0.017	3.719GluAsn: 3.719 ± 0.027	2.449GluPro: 2.449 ± 0.024	2.632GluGln: 2.632 ± 0.031	4.509GluArg: 4.509 ± 0.046	4.656GluSer: 4.656 ± 0.039	4.001GluThr: 4.001 ± 0.037	3.573GluVal: 3.573 ± 0.029	0.684GluTrp: 0.684 ± 0.011	1.916GluTyr: 1.916 ± 0.02	0.021GluXaa: 0.021 ± 0.002
Phe	2.25PheAla: 2.25 ± 0.022	0.792PheCys: 0.792 ± 0.013	1.983PheAsp: 1.983 ± 0.018	2.035PheGlu: 2.035 ± 0.023	1.438PhePhe: 1.438 ± 0.021	2.117PheGly: 2.117 ± 0.026	0.952PheHis: 0.952 ± 0.014	1.989PheIle: 1.989 ± 0.027	1.926PheLys: 1.926 ± 0.02	3.513PheLeu: 3.513 ± 0.034	0.76PheMet: 0.76 ± 0.013	1.639PheAsn: 1.639 ± 0.017	1.68PhePro: 1.68 ± 0.019	1.296PheGln: 1.296 ± 0.016	1.98PheArg: 1.98 ± 0.023	2.792PheSer: 2.792 ± 0.027	2.054PheThr: 2.054 ± 0.022	2.402PheVal: 2.402 ± 0.025	0.429PheTrp: 0.429 ± 0.01	1.257PheTyr: 1.257 ± 0.016	0.009PheXaa: 0.009 ± 0.001
Gly	3.379GlyAla: 3.379 ± 0.031	1.063GlyCys: 1.063 ± 0.022	2.874GlyAsp: 2.874 ± 0.029	3.234GlyGlu: 3.234 ± 0.035	2.017GlyPhe: 2.017 ± 0.022	4.447GlyGly: 4.447 ± 0.072	1.414GlyHis: 1.414 ± 0.02	3.145GlyIle: 3.145 ± 0.03	3.35GlyLys: 3.35 ± 0.027	4.414GlyLeu: 4.414 ± 0.038	1.205GlyMet: 1.205 ± 0.015	2.691GlyAsn: 2.691 ± 0.027	2.41GlyPro: 2.41 ± 0.039	1.978GlyGln: 1.978 ± 0.022	3.516GlyArg: 3.516 ± 0.034	4.543GlySer: 4.543 ± 0.043	3.356GlyThr: 3.356 ± 0.028	3.284GlyVal: 3.284 ± 0.033	0.661GlyTrp: 0.661 ± 0.012	1.89GlyTyr: 1.89 ± 0.026	0.013GlyXaa: 0.013 ± 0.001
His	1.496HisAla: 1.496 ± 0.017	0.581HisCys: 0.581 ± 0.012	1.187HisAsp: 1.187 ± 0.015	1.416HisGlu: 1.416 ± 0.014	0.956HisPhe: 0.956 ± 0.014	1.431HisGly: 1.431 ± 0.018	1.074HisHis: 1.074 ± 0.026	1.378HisIle: 1.378 ± 0.018	1.281HisLys: 1.281 ± 0.015	2.367HisLeu: 2.367 ± 0.021	0.579HisMet: 0.579 ± 0.011	1.118HisAsn: 1.118 ± 0.015	1.385HisPro: 1.385 ± 0.017	1.095HisGln: 1.095 ± 0.017	1.623HisArg: 1.623 ± 0.018	1.896HisSer: 1.896 ± 0.022	1.351HisThr: 1.351 ± 0.018	1.637HisVal: 1.637 ± 0.016	0.283HisTrp: 0.283 ± 0.007	0.855HisTyr: 0.855 ± 0.013	0.007HisXaa: 0.007 ± 0.001
Ile	3.831IleAla: 3.831 ± 0.03	1.293IleCys: 1.293 ± 0.028	3.17IleAsp: 3.17 ± 0.023	3.581IleGlu: 3.581 ± 0.034	2.286IlePhe: 2.286 ± 0.03	2.999IleGly: 2.999 ± 0.028	1.329IleHis: 1.329 ± 0.016	3.366IleIle: 3.366 ± 0.037	3.431IleLys: 3.431 ± 0.031	5.412IleLeu: 5.412 ± 0.049	1.318IleMet: 1.318 ± 0.019	2.875IleAsn: 2.875 ± 0.027	2.911IlePro: 2.911 ± 0.025	2.133IleGln: 2.133 ± 0.02	3.053IleArg: 3.053 ± 0.024	4.528IleSer: 4.528 ± 0.033	3.319IleThr: 3.319 ± 0.027	3.71IleVal: 3.71 ± 0.031	0.564IleTrp: 0.564 ± 0.012	1.806IleTyr: 1.806 ± 0.022	0.018IleXaa: 0.018 ± 0.002
Lys	3.362LysAla: 3.362 ± 0.028	1.223LysCys: 1.223 ± 0.026	3.463LysAsp: 3.463 ± 0.045	4.862LysGlu: 4.862 ± 0.058	2.025LysPhe: 2.025 ± 0.021	2.654LysGly: 2.654 ± 0.028	1.501LysHis: 1.501 ± 0.018	3.82LysIle: 3.82 ± 0.036	5.098LysLys: 5.098 ± 0.053	5.598LysLeu: 5.598 ± 0.047	1.515LysMet: 1.515 ± 0.016	3.175LysAsn: 3.175 ± 0.027	2.743LysPro: 2.743 ± 0.033	2.524LysGln: 2.524 ± 0.024	4.15LysArg: 4.15 ± 0.033	4.594LysSer: 4.594 ± 0.043	3.564LysThr: 3.564 ± 0.03	3.358LysVal: 3.358 ± 0.027	0.671LysTrp: 0.671 ± 0.011	2.057LysTyr: 2.057 ± 0.021	0.02LysXaa: 0.02 ± 0.002
Leu	5.966LeuAla: 5.966 ± 0.045	1.855LeuCys: 1.855 ± 0.026	4.722LeuAsp: 4.722 ± 0.031	5.895LeuGlu: 5.895 ± 0.045	3.098LeuPhe: 3.098 ± 0.034	4.308LeuGly: 4.308 ± 0.035	2.468LeuHis: 2.468 ± 0.022	4.673LeuIle: 4.673 ± 0.043	5.677LeuLys: 5.677 ± 0.047	8.826LeuLeu: 8.826 ± 0.071	1.98LeuMet: 1.98 ± 0.021	4.118LeuAsn: 4.118 ± 0.031	4.823LeuPro: 4.823 ± 0.04	4.235LeuGln: 4.235 ± 0.034	5.736LeuArg: 5.736 ± 0.039	7.231LeuSer: 7.231 ± 0.045	5.129LeuThr: 5.129 ± 0.038	4.96LeuVal: 4.96 ± 0.041	0.95LeuTrp: 0.95 ± 0.017	2.743LeuTyr: 2.743 ± 0.024	0.023LeuXaa: 0.023 ± 0.002
Met	1.533MetAla: 1.533 ± 0.018	0.436MetCys: 0.436 ± 0.01	1.296MetAsp: 1.296 ± 0.016	1.644MetGlu: 1.644 ± 0.018	0.823MetPhe: 0.823 ± 0.012	1.089MetGly: 1.089 ± 0.017	0.563MetHis: 0.563 ± 0.009	1.232MetIle: 1.232 ± 0.019	1.475MetLys: 1.475 ± 0.016	2.018MetLeu: 2.018 ± 0.023	0.613MetMet: 0.613 ± 0.012	1.044MetAsn: 1.044 ± 0.015	1.135MetPro: 1.135 ± 0.014	1.013MetGln: 1.013 ± 0.015	1.39MetArg: 1.39 ± 0.015	1.789MetSer: 1.789 ± 0.019	1.354MetThr: 1.354 ± 0.015	1.223MetVal: 1.223 ± 0.013	0.241MetTrp: 0.241 ± 0.006	0.701MetTyr: 0.701 ± 0.011	0.006MetXaa: 0.006 ± 0.001
Asn	3.162AsnAla: 3.162 ± 0.03	0.954AsnCys: 0.954 ± 0.019	2.749AsnAsp: 2.749 ± 0.025	3.193AsnGlu: 3.193 ± 0.03	1.796AsnPhe: 1.796 ± 0.018	2.874AsnGly: 2.874 ± 0.029	1.082AsnHis: 1.082 ± 0.02	3.182AsnIle: 3.182 ± 0.029	2.924AsnLys: 2.924 ± 0.027	4.364AsnLeu: 4.364 ± 0.032	1.154AsnMet: 1.154 ± 0.011	3.001AsnAsn: 3.001 ± 0.034	2.216AsnPro: 2.216 ± 0.033	1.757AsnGln: 1.757 ± 0.02	2.523AsnArg: 2.523 ± 0.025	3.731AsnSer: 3.731 ± 0.032	2.714AsnThr: 2.714 ± 0.026	3.541AsnVal: 3.541 ± 0.026	0.484AsnTrp: 0.484 ± 0.011	1.613AsnTyr: 1.613 ± 0.02	0.016AsnXaa: 0.016 ± 0.002
Pro	3.272ProAla: 3.272 ± 0.032	0.873ProCys: 0.873 ± 0.05	2.538ProAsp: 2.538 ± 0.022	3.174ProGlu: 3.174 ± 0.038	1.656ProPhe: 1.656 ± 0.019	2.964ProGly: 2.964 ± 0.051	1.213ProHis: 1.213 ± 0.017	2.604ProIle: 2.604 ± 0.024	2.616ProLys: 2.616 ± 0.026	4.185ProLeu: 4.185 ± 0.027	1.014ProMet: 1.014 ± 0.014	2.166ProAsn: 2.166 ± 0.026	4.186ProPro: 4.186 ± 0.062	2.007ProGln: 2.007 ± 0.027	3.119ProArg: 3.119 ± 0.029	4.432ProSer: 4.432 ± 0.046	3.2ProThr: 3.2 ± 0.032	3.201ProVal: 3.201 ± 0.033	0.516ProTrp: 0.516 ± 0.011	1.484ProTyr: 1.484 ± 0.02	0.011ProXaa: 0.011 ± 0.001
Gln	2.381GlnAla: 2.381 ± 0.021	0.793GlnCys: 0.793 ± 0.02	1.955GlnAsp: 1.955 ± 0.019	2.815GlnGlu: 2.815 ± 0.032	1.301GlnPhe: 1.301 ± 0.016	1.78GlnGly: 1.78 ± 0.02	1.167GlnHis: 1.167 ± 0.015	2.196GlnIle: 2.196 ± 0.022	2.434GlnLys: 2.434 ± 0.022	3.681GlnLeu: 3.681 ± 0.031	0.946GlnMet: 0.946 ± 0.016	2.084GlnAsn: 2.084 ± 0.021	1.996GlnPro: 1.996 ± 0.026	3.163GlnGln: 3.163 ± 0.07	2.64GlnArg: 2.64 ± 0.027	2.999GlnSer: 2.999 ± 0.028	2.232GlnThr: 2.232 ± 0.022	2.175GlnVal: 2.175 ± 0.021	0.458GlnTrp: 0.458 ± 0.009	1.246GlnTyr: 1.246 ± 0.017	0.013GlnXaa: 0.013 ± 0.001
Arg	3.83ArgAla: 3.83 ± 0.03	1.301ArgCys: 1.301 ± 0.022	3.465ArgAsp: 3.465 ± 0.032	4.253ArgGlu: 4.253 ± 0.036	2.112ArgPhe: 2.112 ± 0.019	3.501ArgGly: 3.501 ± 0.039	1.747ArgHis: 1.747 ± 0.018	3.294ArgIle: 3.294 ± 0.025	4.235ArgLys: 4.235 ± 0.033	5.403ArgLeu: 5.403 ± 0.037	1.34ArgMet: 1.34 ± 0.013	3.091ArgAsn: 3.091 ± 0.024	2.884ArgPro: 2.884 ± 0.036	2.485ArgGln: 2.485 ± 0.023	5.487ArgArg: 5.487 ± 0.053	4.923ArgSer: 4.923 ± 0.048	3.338ArgThr: 3.338 ± 0.027	3.427ArgVal: 3.427 ± 0.027	0.678ArgTrp: 0.678 ± 0.012	1.956ArgTyr: 1.956 ± 0.018	0.015ArgXaa: 0.015 ± 0.001
Ser	5.029SerAla: 5.029 ± 0.041	1.556SerCys: 1.556 ± 0.037	4.284SerAsp: 4.284 ± 0.031	4.705SerGlu: 4.705 ± 0.039	2.744SerPhe: 2.744 ± 0.025	4.691SerGly: 4.691 ± 0.04	1.894SerHis: 1.894 ± 0.019	4.211SerIle: 4.211 ± 0.029	4.502SerLys: 4.502 ± 0.038	7.005SerLeu: 7.005 ± 0.043	1.708SerMet: 1.708 ± 0.016	3.944SerAsn: 3.944 ± 0.034	4.632SerPro: 4.632 ± 0.052	3.072SerGln: 3.072 ± 0.028	5.073SerArg: 5.073 ± 0.044	8.609SerSer: 8.609 ± 0.082	5.368SerThr: 5.368 ± 0.044	4.86SerVal: 4.86 ± 0.028	0.833SerTrp: 0.833 ± 0.013	2.285SerTyr: 2.285 ± 0.021	0.022SerXaa: 0.022 ± 0.002
Thr	4.152ThrAla: 4.152 ± 0.029	1.283ThrCys: 1.283 ± 0.027	3.066ThrAsp: 3.066 ± 0.024	3.728ThrGlu: 3.728 ± 0.035	2.147ThrPhe: 2.147 ± 0.023	3.351ThrGly: 3.351 ± 0.026	1.333ThrHis: 1.333 ± 0.015	3.419ThrIle: 3.419 ± 0.03	3.399ThrLys: 3.399 ± 0.034	5.353ThrLeu: 5.353 ± 0.038	1.397ThrMet: 1.397 ± 0.015	2.763ThrAsn: 2.763 ± 0.026	3.35ThrPro: 3.35 ± 0.033	2.084ThrGln: 2.084 ± 0.019	3.376ThrArg: 3.376 ± 0.027	5.377ThrSer: 5.377 ± 0.036	4.397ThrThr: 4.397 ± 0.058	3.965ThrVal: 3.965 ± 0.028	0.661ThrTrp: 0.661 ± 0.011	1.774ThrTyr: 1.774 ± 0.02	0.015ThrXaa: 0.015 ± 0.002
Val	4.383ValAla: 4.383 ± 0.035	1.343ValCys: 1.343 ± 0.027	3.337ValAsp: 3.337 ± 0.026	3.897ValGlu: 3.897 ± 0.032	2.209ValPhe: 2.209 ± 0.026	3.159ValGly: 3.159 ± 0.025	1.494ValHis: 1.494 ± 0.015	3.516ValIle: 3.516 ± 0.03	3.624ValLys: 3.624 ± 0.031	5.417ValLeu: 5.417 ± 0.042	1.335ValMet: 1.335 ± 0.016	2.866ValAsn: 2.866 ± 0.03	3.284ValPro: 3.284 ± 0.028	2.479ValGln: 2.479 ± 0.023	3.427ValArg: 3.427 ± 0.023	4.796ValSer: 4.796 ± 0.029	4.037ValThr: 4.037 ± 0.028	3.982ValVal: 3.982 ± 0.03	0.639ValTrp: 0.639 ± 0.012	1.862ValTyr: 1.862 ± 0.019	0.015ValXaa: 0.015 ± 0.002
Trp	0.582TrpAla: 0.582 ± 0.013	0.237TrpCys: 0.237 ± 0.007	0.587TrpAsp: 0.587 ± 0.011	0.604TrpGlu: 0.604 ± 0.011	0.411TrpPhe: 0.411 ± 0.01	0.525TrpGly: 0.525 ± 0.011	0.272TrpHis: 0.272 ± 0.007	0.684TrpIle: 0.684 ± 0.013	0.737TrpLys: 0.737 ± 0.013	1.095TrpLeu: 1.095 ± 0.018	0.275TrpMet: 0.275 ± 0.007	0.579TrpAsn: 0.579 ± 0.013	0.454TrpPro: 0.454 ± 0.011	0.46TrpGln: 0.46 ± 0.01	0.76TrpArg: 0.76 ± 0.011	0.82TrpSer: 0.82 ± 0.014	0.623TrpThr: 0.623 ± 0.012	0.528TrpVal: 0.528 ± 0.01	0.185TrpTrp: 0.185 ± 0.006	0.37TrpTyr: 0.37 ± 0.009	0.003TrpXaa: 0.003 ± 0.001
Tyr	1.834TyrAla: 1.834 ± 0.02	0.723TyrCys: 0.723 ± 0.015	1.705TyrAsp: 1.705 ± 0.02	1.869TyrGlu: 1.869 ± 0.018	1.332TyrPhe: 1.332 ± 0.02	1.769TyrGly: 1.769 ± 0.02	0.851TyrHis: 0.851 ± 0.013	1.792TyrIle: 1.792 ± 0.021	1.821TyrLys: 1.821 ± 0.019	2.89TyrLeu: 2.89 ± 0.03	0.729TyrMet: 0.729 ± 0.011	1.59TyrAsn: 1.59 ± 0.017	1.495TyrPro: 1.495 ± 0.023	1.204TyrGln: 1.204 ± 0.016	1.864TyrArg: 1.864 ± 0.02	2.255TyrSer: 2.255 ± 0.021	1.805TyrThr: 1.805 ± 0.019	1.986TyrVal: 1.986 ± 0.019	0.352TyrTrp: 0.352 ± 0.008	1.199TyrTyr: 1.199 ± 0.017	0.008TyrXaa: 0.008 ± 0.001
Xaa	0.018XaaAla: 0.018 ± 0.002	0.005XaaCys: 0.005 ± 0.001	0.016XaaAsp: 0.016 ± 0.002	0.021XaaGlu: 0.021 ± 0.002	0.011XaaPhe: 0.011 ± 0.001	0.014XaaGly: 0.014 ± 0.002	0.006XaaHis: 0.006 ± 0.001	0.018XaaIle: 0.018 ± 0.002	0.019XaaLys: 0.019 ± 0.002	0.023XaaLeu: 0.023 ± 0.002	0.005XaaMet: 0.005 ± 0.001	0.018XaaAsn: 0.018 ± 0.002	0.01XaaPro: 0.01 ± 0.001	0.009XaaGln: 0.009 ± 0.001	0.012XaaArg: 0.012 ± 0.001	0.022XaaSer: 0.022 ± 0.002	0.018XaaThr: 0.018 ± 0.002	0.018XaaVal: 0.018 ± 0.002	0.003XaaTrp: 0.003 ± 0.001	0.008XaaTyr: 0.008 ± 0.001	0.099XaaXaa: 0.099 ± 0.023

Statistics based on 13035 proteins (7195076 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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