Amino acid dipepetide frequency for Beihai rhabdo-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.997AlaAla: 3.997 ± 1.991
0.266AlaCys: 0.266 ± 0.138
2.931AlaAsp: 2.931 ± 1.651
3.464AlaGlu: 3.464 ± 0.242
1.865AlaPhe: 1.865 ± 0.095
2.665AlaGly: 2.665 ± 1.018
1.332AlaHis: 1.332 ± 0.387
2.931AlaIle: 2.931 ± 2.085
2.931AlaLys: 2.931 ± 1.899
9.592AlaLeu: 9.592 ± 2.204
1.332AlaMet: 1.332 ± 0.387
1.865AlaAsn: 1.865 ± 1.203
2.665AlaPro: 2.665 ± 1.352
3.464AlaGln: 3.464 ± 1.508
3.464AlaArg: 3.464 ± 0.879
6.661AlaSer: 6.661 ± 1.3
3.997AlaThr: 3.997 ± 0.809
2.931AlaVal: 2.931 ± 0.775
0.799AlaTrp: 0.799 ± 0.343
3.197AlaTyr: 3.197 ± 0.646
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.266CysCys: 0.266 ± 0.359
0.533CysAsp: 0.533 ± 0.278
1.066CysGlu: 1.066 ± 0.555
0.533CysPhe: 0.533 ± 0.276
0.799CysGly: 0.799 ± 0.62
1.332CysHis: 1.332 ± 0.515
0.799CysIle: 0.799 ± 0.415
1.066CysLys: 1.066 ± 0.412
2.132CysLeu: 2.132 ± 0.349
0.266CysMet: 0.266 ± 0.138
0.799CysAsn: 0.799 ± 0.343
0.0CysPro: 0.0 ± 0.0
0.266CysGln: 0.266 ± 0.332
0.799CysArg: 0.799 ± 0.415
1.332CysSer: 1.332 ± 0.918
0.799CysThr: 0.799 ± 0.415
0.533CysVal: 0.533 ± 0.276
0.0CysTrp: 0.0 ± 0.0
0.533CysTyr: 0.533 ± 0.303
0.0CysXaa: 0.0 ± 0.0
Asp
1.332AspAla: 1.332 ± 0.707
0.533AspCys: 0.533 ± 0.303
2.132AspAsp: 2.132 ± 0.482
1.599AspGlu: 1.599 ± 0.811
1.865AspPhe: 1.865 ± 0.755
1.332AspGly: 1.332 ± 0.959
1.599AspHis: 1.599 ± 0.668
1.599AspIle: 1.599 ± 0.502
4.263AspLys: 4.263 ± 1.537
7.727AspLeu: 7.727 ± 0.897
0.266AspMet: 0.266 ± 0.138
2.398AspAsn: 2.398 ± 0.399
3.197AspPro: 3.197 ± 1.546
4.263AspGln: 4.263 ± 0.7
1.599AspArg: 1.599 ± 0.393
2.132AspSer: 2.132 ± 0.163
2.398AspThr: 2.398 ± 0.261
1.865AspVal: 1.865 ± 0.783
0.533AspTrp: 0.533 ± 0.304
1.332AspTyr: 1.332 ± 0.211
0.0AspXaa: 0.0 ± 0.0
Glu
4.796GluAla: 4.796 ± 0.878
0.533GluCys: 0.533 ± 0.276
2.931GluAsp: 2.931 ± 0.951
4.263GluGlu: 4.263 ± 1.221
2.931GluPhe: 2.931 ± 1.334
2.398GluGly: 2.398 ± 0.432
1.066GluHis: 1.066 ± 0.393
1.865GluIle: 1.865 ± 0.737
2.132GluLys: 2.132 ± 0.858
6.928GluLeu: 6.928 ± 2.727
1.865GluMet: 1.865 ± 0.968
1.599GluAsn: 1.599 ± 0.633
1.865GluPro: 1.865 ± 0.503
3.73GluGln: 3.73 ± 0.476
3.464GluArg: 3.464 ± 0.8
3.997GluSer: 3.997 ± 0.636
3.997GluThr: 3.997 ± 0.845
4.263GluVal: 4.263 ± 0.279
0.799GluTrp: 0.799 ± 0.334
2.132GluTyr: 2.132 ± 0.318
0.0GluXaa: 0.0 ± 0.0
Phe
2.665PheAla: 2.665 ± 0.743
1.066PheCys: 1.066 ± 0.393
1.332PheAsp: 1.332 ± 0.298
1.865PheGlu: 1.865 ± 0.928
1.066PhePhe: 1.066 ± 0.553
2.132PheGly: 2.132 ± 0.591
1.865PheHis: 1.865 ± 0.364
1.066PheIle: 1.066 ± 0.241
2.931PheLys: 2.931 ± 0.704
5.063PheLeu: 5.063 ± 1.278
0.799PheMet: 0.799 ± 0.266
1.066PheAsn: 1.066 ± 0.412
2.665PhePro: 2.665 ± 1.018
3.464PheGln: 3.464 ± 1.081
1.332PheArg: 1.332 ± 0.513
3.464PheSer: 3.464 ± 0.881
2.398PheThr: 2.398 ± 0.392
2.398PheVal: 2.398 ± 0.654
0.799PheTrp: 0.799 ± 0.62
1.865PheTyr: 1.865 ± 0.531
0.0PheXaa: 0.0 ± 0.0
Gly
3.464GlyAla: 3.464 ± 0.196
0.266GlyCys: 0.266 ± 0.138
2.665GlyAsp: 2.665 ± 0.704
2.398GlyGlu: 2.398 ± 0.732
1.865GlyPhe: 1.865 ± 0.92
3.197GlyGly: 3.197 ± 1.123
1.599GlyHis: 1.599 ± 0.668
3.464GlyIle: 3.464 ± 1.081
2.398GlyLys: 2.398 ± 0.675
6.661GlyLeu: 6.661 ± 1.262
0.799GlyMet: 0.799 ± 0.343
1.865GlyAsn: 1.865 ± 0.731
2.665GlyPro: 2.665 ± 0.471
1.332GlyGln: 1.332 ± 0.387
1.599GlyArg: 1.599 ± 0.829
3.997GlySer: 3.997 ± 1.04
2.398GlyThr: 2.398 ± 0.732
3.73GlyVal: 3.73 ± 0.916
0.533GlyTrp: 0.533 ± 0.278
1.332GlyTyr: 1.332 ± 1.316
0.0GlyXaa: 0.0 ± 0.0
His
2.132HisAla: 2.132 ± 1.106
1.332HisCys: 1.332 ± 0.515
0.799HisAsp: 0.799 ± 0.343
0.266HisGlu: 0.266 ± 0.138
1.066HisPhe: 1.066 ± 0.602
0.799HisGly: 0.799 ± 0.62
1.066HisHis: 1.066 ± 0.553
1.865HisIle: 1.865 ± 0.458
1.066HisLys: 1.066 ± 0.553
5.596HisLeu: 5.596 ± 0.905
0.799HisMet: 0.799 ± 0.415
0.533HisAsn: 0.533 ± 0.446
3.197HisPro: 3.197 ± 0.369
2.132HisGln: 2.132 ± 0.591
1.066HisArg: 1.066 ± 0.412
2.665HisSer: 2.665 ± 1.067
0.799HisThr: 0.799 ± 0.415
1.599HisVal: 1.599 ± 1.24
1.066HisTrp: 1.066 ± 0.296
0.799HisTyr: 0.799 ± 0.415
0.0HisXaa: 0.0 ± 0.0
Ile
3.997IleAla: 3.997 ± 1.422
1.332IleCys: 1.332 ± 0.622
3.197IleAsp: 3.197 ± 0.879
3.73IleGlu: 3.73 ± 0.99
1.865IlePhe: 1.865 ± 0.624
2.132IleGly: 2.132 ± 0.61
1.865IleHis: 1.865 ± 0.494
4.796IleIle: 4.796 ± 1.042
3.197IleLys: 3.197 ± 0.762
7.194IleLeu: 7.194 ± 1.109
1.066IleMet: 1.066 ± 0.553
2.398IleAsn: 2.398 ± 1.459
5.329IlePro: 5.329 ± 1.205
1.599IleGln: 1.599 ± 0.626
3.197IleArg: 3.197 ± 1.123
3.73IleSer: 3.73 ± 1.527
3.197IleThr: 3.197 ± 0.646
2.398IleVal: 2.398 ± 0.747
1.066IleTrp: 1.066 ± 0.602
0.799IleTyr: 0.799 ± 0.627
0.0IleXaa: 0.0 ± 0.0
Lys
3.997LysAla: 3.997 ± 1.489
0.266LysCys: 0.266 ± 0.332
2.665LysAsp: 2.665 ± 0.774
3.73LysGlu: 3.73 ± 1.032
2.398LysPhe: 2.398 ± 0.432
2.132LysGly: 2.132 ± 0.484
0.533LysHis: 0.533 ± 0.304
4.263LysIle: 4.263 ± 1.044
2.132LysLys: 2.132 ± 0.352
2.665LysLeu: 2.665 ± 0.752
2.398LysMet: 2.398 ± 1.014
1.599LysAsn: 1.599 ± 0.502
2.931LysPro: 2.931 ± 0.794
1.066LysGln: 1.066 ± 0.241
1.865LysArg: 1.865 ± 0.83
3.997LysSer: 3.997 ± 0.995
4.53LysThr: 4.53 ± 1.473
3.464LysVal: 3.464 ± 0.612
1.865LysTrp: 1.865 ± 0.909
0.799LysTyr: 0.799 ± 0.415
0.0LysXaa: 0.0 ± 0.0
Leu
9.059LeuAla: 9.059 ± 1.698
2.132LeuCys: 2.132 ± 0.524
5.063LeuAsp: 5.063 ± 0.794
7.727LeuGlu: 7.727 ± 2.532
4.796LeuPhe: 4.796 ± 0.908
3.997LeuGly: 3.997 ± 1.183
4.263LeuHis: 4.263 ± 1.268
5.329LeuIle: 5.329 ± 1.31
6.661LeuLys: 6.661 ± 1.578
10.925LeuLeu: 10.925 ± 0.823
3.73LeuMet: 3.73 ± 0.29
3.73LeuAsn: 3.73 ± 0.535
10.658LeuPro: 10.658 ± 0.65
3.464LeuGln: 3.464 ± 0.705
5.862LeuArg: 5.862 ± 0.614
8.793LeuSer: 8.793 ± 1.372
7.461LeuThr: 7.461 ± 2.121
7.994LeuVal: 7.994 ± 1.268
0.799LeuTrp: 0.799 ± 0.415
3.464LeuTyr: 3.464 ± 1.22
0.0LeuXaa: 0.0 ± 0.0
Met
2.665MetAla: 2.665 ± 1.522
0.0MetCys: 0.0 ± 0.0
1.599MetAsp: 1.599 ± 0.502
2.398MetGlu: 2.398 ± 0.481
1.332MetPhe: 1.332 ± 0.691
1.332MetGly: 1.332 ± 0.211
0.533MetHis: 0.533 ± 0.276
1.599MetIle: 1.599 ± 0.633
1.066MetLys: 1.066 ± 1.093
1.332MetLeu: 1.332 ± 0.493
0.266MetMet: 0.266 ± 0.359
1.332MetAsn: 1.332 ± 0.211
1.066MetPro: 1.066 ± 0.393
0.533MetGln: 0.533 ± 0.276
1.066MetArg: 1.066 ± 0.376
2.665MetSer: 2.665 ± 0.316
2.665MetThr: 2.665 ± 0.668
2.398MetVal: 2.398 ± 0.285
0.0MetTrp: 0.0 ± 0.0
0.799MetTyr: 0.799 ± 0.251
0.0MetXaa: 0.0 ± 0.0
Asn
1.865AsnAla: 1.865 ± 0.755
0.266AsnCys: 0.266 ± 0.138
0.533AsnAsp: 0.533 ± 0.276
1.599AsnGlu: 1.599 ± 0.172
1.599AsnPhe: 1.599 ± 0.37
1.599AsnGly: 1.599 ± 0.662
2.398AsnHis: 2.398 ± 0.611
2.398AsnIle: 2.398 ± 0.261
1.599AsnLys: 1.599 ± 0.833
3.73AsnLeu: 3.73 ± 0.799
0.799AsnMet: 0.799 ± 0.299
1.865AsnAsn: 1.865 ± 0.462
2.931AsnPro: 2.931 ± 0.775
1.332AsnGln: 1.332 ± 0.493
1.865AsnArg: 1.865 ± 0.458
2.665AsnSer: 2.665 ± 0.471
3.197AsnThr: 3.197 ± 0.867
1.332AsnVal: 1.332 ± 0.511
0.266AsnTrp: 0.266 ± 0.138
1.332AsnTyr: 1.332 ± 0.323
0.0AsnXaa: 0.0 ± 0.0
Pro
3.997ProAla: 3.997 ± 2.797
0.266ProCys: 0.266 ± 0.138
1.066ProAsp: 1.066 ± 0.412
4.796ProGlu: 4.796 ± 0.808
3.197ProPhe: 3.197 ± 1.287
2.398ProGly: 2.398 ± 1.244
2.665ProHis: 2.665 ± 0.633
4.263ProIle: 4.263 ± 1.393
1.865ProLys: 1.865 ± 0.706
6.661ProLeu: 6.661 ± 1.658
1.066ProMet: 1.066 ± 0.277
1.332ProAsn: 1.332 ± 0.661
4.53ProPro: 4.53 ± 1.988
3.73ProGln: 3.73 ± 0.928
3.73ProArg: 3.73 ± 1.714
7.994ProSer: 7.994 ± 1.492
3.997ProThr: 3.997 ± 0.836
5.329ProVal: 5.329 ± 1.193
0.533ProTrp: 0.533 ± 0.276
2.132ProTyr: 2.132 ± 0.579
0.0ProXaa: 0.0 ± 0.0
Gln
1.066GlnAla: 1.066 ± 0.555
0.799GlnCys: 0.799 ± 0.334
1.865GlnAsp: 1.865 ± 0.913
2.398GlnGlu: 2.398 ± 0.827
1.332GlnPhe: 1.332 ± 0.347
1.599GlnGly: 1.599 ± 0.172
1.332GlnHis: 1.332 ± 0.387
2.931GlnIle: 2.931 ± 0.556
3.197GlnLys: 3.197 ± 0.604
6.928GlnLeu: 6.928 ± 0.783
0.799GlnMet: 0.799 ± 0.841
1.332GlnAsn: 1.332 ± 0.716
1.332GlnPro: 1.332 ± 0.557
2.132GlnGln: 2.132 ± 0.57
1.865GlnArg: 1.865 ± 0.562
3.197GlnSer: 3.197 ± 0.552
2.132GlnThr: 2.132 ± 0.823
4.263GlnVal: 4.263 ± 1.017
0.799GlnTrp: 0.799 ± 0.415
2.665GlnTyr: 2.665 ± 0.471
0.0GlnXaa: 0.0 ± 0.0
Arg
1.332ArgAla: 1.332 ± 0.493
0.533ArgCys: 0.533 ± 0.276
1.066ArgAsp: 1.066 ± 0.296
3.73ArgGlu: 3.73 ± 1.099
2.132ArgPhe: 2.132 ± 0.885
3.464ArgGly: 3.464 ± 1.081
1.599ArgHis: 1.599 ± 0.633
2.665ArgIle: 2.665 ± 0.576
2.931ArgLys: 2.931 ± 1.067
5.329ArgLeu: 5.329 ± 1.692
1.066ArgMet: 1.066 ± 0.241
1.599ArgAsn: 1.599 ± 0.37
3.73ArgPro: 3.73 ± 0.799
1.332ArgGln: 1.332 ± 0.387
2.931ArgArg: 2.931 ± 0.962
3.464ArgSer: 3.464 ± 1.335
3.73ArgThr: 3.73 ± 1.39
3.73ArgVal: 3.73 ± 0.713
0.799ArgTrp: 0.799 ± 0.251
1.066ArgTyr: 1.066 ± 0.555
0.0ArgXaa: 0.0 ± 0.0
Ser
5.063SerAla: 5.063 ± 1.519
1.066SerCys: 1.066 ± 0.296
2.931SerAsp: 2.931 ± 0.962
3.464SerGlu: 3.464 ± 1.78
3.197SerPhe: 3.197 ± 1.235
7.194SerGly: 7.194 ± 1.363
1.599SerHis: 1.599 ± 0.393
6.128SerIle: 6.128 ± 1.586
1.865SerLys: 1.865 ± 0.363
9.592SerLeu: 9.592 ± 3.028
3.197SerMet: 3.197 ± 1.091
1.066SerAsn: 1.066 ± 0.412
6.661SerPro: 6.661 ± 1.006
3.464SerGln: 3.464 ± 0.705
2.398SerArg: 2.398 ± 0.702
7.994SerSer: 7.994 ± 2.124
5.596SerThr: 5.596 ± 0.99
6.395SerVal: 6.395 ± 1.452
0.799SerTrp: 0.799 ± 0.251
1.599SerTyr: 1.599 ± 0.264
0.0SerXaa: 0.0 ± 0.0
Thr
4.263ThrAla: 4.263 ± 1.898
0.799ThrCys: 0.799 ± 0.334
3.997ThrAsp: 3.997 ± 0.273
3.997ThrGlu: 3.997 ± 1.743
2.931ThrPhe: 2.931 ± 0.53
2.931ThrGly: 2.931 ± 0.806
1.332ThrHis: 1.332 ± 0.515
4.53ThrIle: 4.53 ± 0.717
3.197ThrLys: 3.197 ± 0.467
5.862ThrLeu: 5.862 ± 1.608
1.599ThrMet: 1.599 ± 0.502
2.665ThrAsn: 2.665 ± 0.423
4.796ThrPro: 4.796 ± 0.994
1.865ThrGln: 1.865 ± 0.363
2.132ThrArg: 2.132 ± 0.952
4.796ThrSer: 4.796 ± 1.001
4.53ThrThr: 4.53 ± 1.049
3.464ThrVal: 3.464 ± 1.146
1.599ThrTrp: 1.599 ± 0.633
1.865ThrTyr: 1.865 ± 0.928
0.0ThrXaa: 0.0 ± 0.0
Val
3.197ValAla: 3.197 ± 0.685
1.066ValCys: 1.066 ± 0.621
2.665ValAsp: 2.665 ± 0.704
3.73ValGlu: 3.73 ± 0.316
4.53ValPhe: 4.53 ± 1.38
4.263ValGly: 4.263 ± 1.221
1.599ValHis: 1.599 ± 0.668
3.464ValIle: 3.464 ± 0.613
3.464ValLys: 3.464 ± 0.427
8.527ValLeu: 8.527 ± 0.928
2.931ValMet: 2.931 ± 1.099
3.464ValAsn: 3.464 ± 0.666
2.665ValPro: 2.665 ± 0.423
1.865ValGln: 1.865 ± 0.458
3.997ValArg: 3.997 ± 1.183
2.931ValSer: 2.931 ± 0.736
2.398ValThr: 2.398 ± 0.808
6.928ValVal: 6.928 ± 0.949
1.066ValTrp: 1.066 ± 0.553
2.132ValTyr: 2.132 ± 0.753
0.0ValXaa: 0.0 ± 0.0
Trp
1.599TrpAla: 1.599 ± 0.501
0.266TrpCys: 0.266 ± 0.138
2.398TrpAsp: 2.398 ± 0.716
0.533TrpGlu: 0.533 ± 0.276
0.266TrpPhe: 0.266 ± 0.359
0.266TrpGly: 0.266 ± 0.138
0.266TrpHis: 0.266 ± 0.359
0.533TrpIle: 0.533 ± 0.304
0.533TrpLys: 0.533 ± 0.426
1.066TrpLeu: 1.066 ± 0.303
0.799TrpMet: 0.799 ± 0.415
0.799TrpAsn: 0.799 ± 0.334
0.266TrpPro: 0.266 ± 0.138
0.266TrpGln: 0.266 ± 0.138
0.799TrpArg: 0.799 ± 0.323
0.799TrpSer: 0.799 ± 0.415
1.332TrpThr: 1.332 ± 0.211
0.533TrpVal: 0.533 ± 0.276
0.799TrpTrp: 0.799 ± 0.251
0.799TrpTyr: 0.799 ± 0.334
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.865TyrAla: 1.865 ± 0.531
0.799TyrCys: 0.799 ± 0.996
1.599TyrAsp: 1.599 ± 0.472
0.799TyrGlu: 0.799 ± 0.627
0.533TyrPhe: 0.533 ± 0.276
1.599TyrGly: 1.599 ± 1.24
0.799TyrHis: 0.799 ± 0.331
1.599TyrIle: 1.599 ± 0.422
0.799TyrLys: 0.799 ± 0.681
2.398TyrLeu: 2.398 ± 0.547
0.533TyrMet: 0.533 ± 0.276
1.865TyrAsn: 1.865 ± 0.095
2.665TyrPro: 2.665 ± 0.776
2.665TyrGln: 2.665 ± 0.774
3.197TyrArg: 3.197 ± 0.526
3.997TyrSer: 3.997 ± 0.709
1.599TyrThr: 1.599 ± 0.852
1.332TyrVal: 1.332 ± 0.347
0.0TyrTrp: 0.0 ± 0.0
2.398TyrTyr: 2.398 ± 0.743
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3754 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski