Amino acid dipepetide frequency for Priestia filamentosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.853AlaAla: 4.853 ± 0.075
0.593AlaCys: 0.593 ± 0.021
2.833AlaAsp: 2.833 ± 0.042
4.145AlaGlu: 4.145 ± 0.06
3.356AlaPhe: 3.356 ± 0.056
4.744AlaGly: 4.744 ± 0.077
1.434AlaHis: 1.434 ± 0.033
5.484AlaIle: 5.484 ± 0.078
4.579AlaLys: 4.579 ± 0.059
7.482AlaLeu: 7.482 ± 0.077
1.848AlaMet: 1.848 ± 0.036
2.629AlaAsn: 2.629 ± 0.049
2.08AlaPro: 2.08 ± 0.042
2.293AlaGln: 2.293 ± 0.052
2.615AlaArg: 2.615 ± 0.044
4.177AlaSer: 4.177 ± 0.057
3.549AlaThr: 3.549 ± 0.126
5.126AlaVal: 5.126 ± 0.061
0.551AlaTrp: 0.551 ± 0.022
2.339AlaTyr: 2.339 ± 0.036
0.0AlaXaa: 0.0 ± 0.0
Cys
0.489CysAla: 0.489 ± 0.019
0.11CysCys: 0.11 ± 0.008
0.38CysAsp: 0.38 ± 0.017
0.537CysGlu: 0.537 ± 0.022
0.389CysPhe: 0.389 ± 0.017
0.664CysGly: 0.664 ± 0.025
0.224CysHis: 0.224 ± 0.013
0.588CysIle: 0.588 ± 0.021
0.408CysLys: 0.408 ± 0.016
0.831CysLeu: 0.831 ± 0.024
0.21CysMet: 0.21 ± 0.013
0.317CysAsn: 0.317 ± 0.016
0.315CysPro: 0.315 ± 0.017
0.257CysGln: 0.257 ± 0.013
0.305CysArg: 0.305 ± 0.013
0.575CysSer: 0.575 ± 0.025
0.418CysThr: 0.418 ± 0.017
0.455CysVal: 0.455 ± 0.018
0.075CysTrp: 0.075 ± 0.008
0.301CysTyr: 0.301 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
2.783AspAla: 2.783 ± 0.047
0.357AspCys: 0.357 ± 0.018
2.208AspAsp: 2.208 ± 0.055
4.192AspGlu: 4.192 ± 0.06
2.286AspPhe: 2.286 ± 0.04
3.208AspGly: 3.208 ± 0.049
1.085AspHis: 1.085 ± 0.025
3.967AspIle: 3.967 ± 0.059
3.092AspLys: 3.092 ± 0.049
4.626AspLeu: 4.626 ± 0.06
1.227AspMet: 1.227 ± 0.029
1.746AspAsn: 1.746 ± 0.038
1.655AspPro: 1.655 ± 0.038
1.628AspGln: 1.628 ± 0.042
2.015AspArg: 2.015 ± 0.04
2.52AspSer: 2.52 ± 0.05
2.211AspThr: 2.211 ± 0.046
3.725AspVal: 3.725 ± 0.057
0.542AspTrp: 0.542 ± 0.02
2.076AspTyr: 2.076 ± 0.041
0.0AspXaa: 0.0 ± 0.0
Glu
5.207GluAla: 5.207 ± 0.064
0.415GluCys: 0.415 ± 0.019
3.981GluAsp: 3.981 ± 0.058
8.387GluGlu: 8.387 ± 0.104
2.515GluPhe: 2.515 ± 0.049
4.721GluGly: 4.721 ± 0.065
1.665GluHis: 1.665 ± 0.034
5.396GluIle: 5.396 ± 0.064
7.306GluLys: 7.306 ± 0.085
6.937GluLeu: 6.937 ± 0.078
2.241GluMet: 2.241 ± 0.047
3.838GluAsn: 3.838 ± 0.057
1.794GluPro: 1.794 ± 0.037
3.332GluGln: 3.332 ± 0.054
3.814GluArg: 3.814 ± 0.053
3.495GluSer: 3.495 ± 0.058
3.937GluThr: 3.937 ± 0.061
5.166GluVal: 5.166 ± 0.07
0.788GluTrp: 0.788 ± 0.019
2.23GluTyr: 2.23 ± 0.039
0.0GluXaa: 0.0 ± 0.0
Phe
2.81PheAla: 2.81 ± 0.049
0.396PheCys: 0.396 ± 0.016
2.146PheAsp: 2.146 ± 0.044
2.684PheGlu: 2.684 ± 0.048
2.611PhePhe: 2.611 ± 0.055
3.329PheGly: 3.329 ± 0.054
1.07PheHis: 1.07 ± 0.028
3.998PheIle: 3.998 ± 0.063
2.631PheLys: 2.631 ± 0.043
5.148PheLeu: 5.148 ± 0.077
1.188PheMet: 1.188 ± 0.031
1.875PheAsn: 1.875 ± 0.033
1.71PhePro: 1.71 ± 0.031
1.66PheGln: 1.66 ± 0.035
1.448PheArg: 1.448 ± 0.029
3.549PheSer: 3.549 ± 0.052
2.688PheThr: 2.688 ± 0.049
3.227PheVal: 3.227 ± 0.049
0.47PheTrp: 0.47 ± 0.019
1.745PheTyr: 1.745 ± 0.035
0.0PheXaa: 0.0 ± 0.0
Gly
5.142GlyAla: 5.142 ± 0.136
0.647GlyCys: 0.647 ± 0.022
3.075GlyAsp: 3.075 ± 0.054
4.915GlyGlu: 4.915 ± 0.066
3.392GlyPhe: 3.392 ± 0.057
5.058GlyGly: 5.058 ± 0.076
1.325GlyHis: 1.325 ± 0.031
6.005GlyIle: 6.005 ± 0.082
4.978GlyLys: 4.978 ± 0.062
6.501GlyLeu: 6.501 ± 0.083
2.061GlyMet: 2.061 ± 0.044
2.642GlyAsn: 2.642 ± 0.048
1.752GlyPro: 1.752 ± 0.058
2.024GlyGln: 2.024 ± 0.042
2.635GlyArg: 2.635 ± 0.043
4.028GlySer: 4.028 ± 0.065
4.18GlyThr: 4.18 ± 0.081
5.404GlyVal: 5.404 ± 0.109
0.778GlyTrp: 0.778 ± 0.021
2.821GlyTyr: 2.821 ± 0.043
0.0GlyXaa: 0.0 ± 0.0
His
1.208HisAla: 1.208 ± 0.029
0.224HisCys: 0.224 ± 0.014
1.001HisAsp: 1.001 ± 0.027
1.49HisGlu: 1.49 ± 0.031
1.103HisPhe: 1.103 ± 0.032
1.425HisGly: 1.425 ± 0.034
0.768HisHis: 0.768 ± 0.028
1.73HisIle: 1.73 ± 0.031
1.289HisLys: 1.289 ± 0.033
2.27HisLeu: 2.27 ± 0.041
0.537HisMet: 0.537 ± 0.018
0.893HisAsn: 0.893 ± 0.024
1.088HisPro: 1.088 ± 0.029
0.77HisGln: 0.77 ± 0.023
0.908HisArg: 0.908 ± 0.027
1.296HisSer: 1.296 ± 0.033
1.082HisThr: 1.082 ± 0.024
1.47HisVal: 1.47 ± 0.03
0.205HisTrp: 0.205 ± 0.011
0.988HisTyr: 0.988 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.738IleAla: 5.738 ± 0.078
0.732IleCys: 0.732 ± 0.023
3.898IleAsp: 3.898 ± 0.058
5.737IleGlu: 5.737 ± 0.069
3.243IlePhe: 3.243 ± 0.06
6.102IleGly: 6.102 ± 0.078
1.675IleHis: 1.675 ± 0.035
5.706IleIle: 5.706 ± 0.07
4.712IleLys: 4.712 ± 0.062
7.115IleLeu: 7.115 ± 0.085
1.745IleMet: 1.745 ± 0.036
3.201IleAsn: 3.201 ± 0.044
3.253IlePro: 3.253 ± 0.048
2.73IleGln: 2.73 ± 0.045
2.897IleArg: 2.897 ± 0.052
5.167IleSer: 5.167 ± 0.058
4.317IleThr: 4.317 ± 0.062
5.701IleVal: 5.701 ± 0.073
0.615IleTrp: 0.615 ± 0.021
2.389IleTyr: 2.389 ± 0.042
0.0IleXaa: 0.0 ± 0.0
Lys
4.921LysAla: 4.921 ± 0.071
0.378LysCys: 0.378 ± 0.018
3.943LysAsp: 3.943 ± 0.058
8.209LysGlu: 8.209 ± 0.089
1.942LysPhe: 1.942 ± 0.036
5.009LysGly: 5.009 ± 0.063
1.403LysHis: 1.403 ± 0.033
4.577LysIle: 4.577 ± 0.057
6.648LysLys: 6.648 ± 0.091
5.998LysLeu: 5.998 ± 0.072
2.212LysMet: 2.212 ± 0.036
3.314LysAsn: 3.314 ± 0.054
2.094LysPro: 2.094 ± 0.042
2.947LysGln: 2.947 ± 0.055
3.644LysArg: 3.644 ± 0.05
3.664LysSer: 3.664 ± 0.047
3.851LysThr: 3.851 ± 0.053
5.043LysVal: 5.043 ± 0.065
0.863LysTrp: 0.863 ± 0.028
2.223LysTyr: 2.223 ± 0.041
0.0LysXaa: 0.0 ± 0.0
Leu
7.08LeuAla: 7.08 ± 0.077
0.838LeuCys: 0.838 ± 0.025
4.484LeuAsp: 4.484 ± 0.065
6.457LeuGlu: 6.457 ± 0.076
5.319LeuPhe: 5.319 ± 0.083
6.669LeuGly: 6.669 ± 0.086
2.135LeuHis: 2.135 ± 0.041
7.141LeuIle: 7.141 ± 0.101
6.835LeuLys: 6.835 ± 0.071
10.809LeuLeu: 10.809 ± 0.126
2.423LeuMet: 2.423 ± 0.043
4.215LeuAsn: 4.215 ± 0.055
3.812LeuPro: 3.812 ± 0.05
3.799LeuGln: 3.799 ± 0.053
3.474LeuArg: 3.474 ± 0.05
7.483LeuSer: 7.483 ± 0.083
5.814LeuThr: 5.814 ± 0.062
6.37LeuVal: 6.37 ± 0.068
0.891LeuTrp: 0.891 ± 0.03
3.442LeuTyr: 3.442 ± 0.06
0.0LeuXaa: 0.0 ± 0.0
Met
1.812MetAla: 1.812 ± 0.038
0.163MetCys: 0.163 ± 0.011
1.225MetAsp: 1.225 ± 0.029
1.848MetGlu: 1.848 ± 0.036
1.111MetPhe: 1.111 ± 0.029
1.738MetGly: 1.738 ± 0.036
0.388MetHis: 0.388 ± 0.018
2.071MetIle: 2.071 ± 0.038
2.721MetLys: 2.721 ± 0.042
2.559MetLeu: 2.559 ± 0.042
0.863MetMet: 0.863 ± 0.029
1.576MetAsn: 1.576 ± 0.037
0.959MetPro: 0.959 ± 0.042
0.729MetGln: 0.729 ± 0.021
1.053MetArg: 1.053 ± 0.028
1.715MetSer: 1.715 ± 0.034
1.547MetThr: 1.547 ± 0.034
1.583MetVal: 1.583 ± 0.033
0.209MetTrp: 0.209 ± 0.013
0.737MetTyr: 0.737 ± 0.023
0.0MetXaa: 0.0 ± 0.0
Asn
2.625AsnAla: 2.625 ± 0.046
0.328AsnCys: 0.328 ± 0.018
1.977AsnAsp: 1.977 ± 0.038
3.472AsnGlu: 3.472 ± 0.06
1.679AsnPhe: 1.679 ± 0.034
3.121AsnGly: 3.121 ± 0.047
1.001AsnHis: 1.001 ± 0.026
3.672AsnIle: 3.672 ± 0.051
3.179AsnLys: 3.179 ± 0.053
3.976AsnLeu: 3.976 ± 0.05
1.205AsnMet: 1.205 ± 0.028
1.969AsnAsn: 1.969 ± 0.045
2.037AsnPro: 2.037 ± 0.047
1.6AsnGln: 1.6 ± 0.036
1.995AsnArg: 1.995 ± 0.044
2.361AsnSer: 2.361 ± 0.046
2.183AsnThr: 2.183 ± 0.043
3.281AsnVal: 3.281 ± 0.053
0.447AsnTrp: 0.447 ± 0.019
1.554AsnTyr: 1.554 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
2.004ProAla: 2.004 ± 0.041
0.237ProCys: 0.237 ± 0.014
1.602ProAsp: 1.602 ± 0.04
2.56ProGlu: 2.56 ± 0.045
2.127ProPhe: 2.127 ± 0.043
1.978ProGly: 1.978 ± 0.043
0.929ProHis: 0.929 ± 0.028
2.631ProIle: 2.631 ± 0.042
2.252ProLys: 2.252 ± 0.038
3.89ProLeu: 3.89 ± 0.059
0.715ProMet: 0.715 ± 0.025
1.649ProAsn: 1.649 ± 0.04
1.036ProPro: 1.036 ± 0.027
1.136ProGln: 1.136 ± 0.032
1.071ProArg: 1.071 ± 0.03
2.542ProSer: 2.542 ± 0.044
2.056ProThr: 2.056 ± 0.059
2.519ProVal: 2.519 ± 0.05
0.394ProTrp: 0.394 ± 0.017
1.496ProTyr: 1.496 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
2.445GlnAla: 2.445 ± 0.047
0.233GlnCys: 0.233 ± 0.013
1.612GlnAsp: 1.612 ± 0.033
2.913GlnGlu: 2.913 ± 0.053
1.475GlnPhe: 1.475 ± 0.032
2.329GlnGly: 2.329 ± 0.044
0.846GlnHis: 0.846 ± 0.021
2.206GlnIle: 2.206 ± 0.04
3.051GlnLys: 3.051 ± 0.05
3.266GlnLeu: 3.266 ± 0.054
0.949GlnMet: 0.949 ± 0.027
1.84GlnAsn: 1.84 ± 0.033
1.134GlnPro: 1.134 ± 0.031
1.635GlnGln: 1.635 ± 0.054
1.528GlnArg: 1.528 ± 0.036
2.143GlnSer: 2.143 ± 0.044
1.958GlnThr: 1.958 ± 0.034
1.96GlnVal: 1.96 ± 0.034
0.399GlnTrp: 0.399 ± 0.016
1.484GlnTyr: 1.484 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
2.473ArgAla: 2.473 ± 0.045
0.263ArgCys: 0.263 ± 0.013
2.045ArgAsp: 2.045 ± 0.039
3.545ArgGlu: 3.545 ± 0.055
1.876ArgPhe: 1.876 ± 0.04
2.329ArgGly: 2.329 ± 0.038
0.799ArgHis: 0.799 ± 0.023
2.988ArgIle: 2.988 ± 0.048
3.353ArgLys: 3.353 ± 0.044
3.891ArgLeu: 3.891 ± 0.057
1.139ArgMet: 1.139 ± 0.03
1.938ArgAsn: 1.938 ± 0.036
1.242ArgPro: 1.242 ± 0.034
1.399ArgGln: 1.399 ± 0.033
1.815ArgArg: 1.815 ± 0.047
2.204ArgSer: 2.204 ± 0.037
2.105ArgThr: 2.105 ± 0.036
2.619ArgVal: 2.619 ± 0.039
0.413ArgTrp: 0.413 ± 0.019
1.587ArgTyr: 1.587 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
3.682SerAla: 3.682 ± 0.058
0.497SerCys: 0.497 ± 0.02
2.549SerAsp: 2.549 ± 0.043
3.916SerGlu: 3.916 ± 0.057
3.673SerPhe: 3.673 ± 0.054
4.236SerGly: 4.236 ± 0.061
1.378SerHis: 1.378 ± 0.033
5.284SerIle: 5.284 ± 0.07
4.027SerLys: 4.027 ± 0.05
7.201SerLeu: 7.201 ± 0.074
1.678SerMet: 1.678 ± 0.033
2.461SerAsn: 2.461 ± 0.046
2.263SerPro: 2.263 ± 0.042
2.086SerGln: 2.086 ± 0.038
2.239SerArg: 2.239 ± 0.034
4.753SerSer: 4.753 ± 0.074
3.394SerThr: 3.394 ± 0.056
4.189SerVal: 4.189 ± 0.059
0.631SerTrp: 0.631 ± 0.021
2.553SerTyr: 2.553 ± 0.042
0.0SerXaa: 0.0 ± 0.0
Thr
3.795ThrAla: 3.795 ± 0.051
0.394ThrCys: 0.394 ± 0.017
2.372ThrAsp: 2.372 ± 0.042
3.588ThrGlu: 3.588 ± 0.05
2.905ThrPhe: 2.905 ± 0.053
4.407ThrGly: 4.407 ± 0.338
1.12ThrHis: 1.12 ± 0.029
4.312ThrIle: 4.312 ± 0.06
3.692ThrLys: 3.692 ± 0.058
5.664ThrLeu: 5.664 ± 0.072
1.3ThrMet: 1.3 ± 0.03
2.415ThrAsn: 2.415 ± 0.042
2.314ThrPro: 2.314 ± 0.042
1.359ThrGln: 1.359 ± 0.031
1.853ThrArg: 1.853 ± 0.034
3.509ThrSer: 3.509 ± 0.056
3.098ThrThr: 3.098 ± 0.076
4.297ThrVal: 4.297 ± 0.059
0.562ThrTrp: 0.562 ± 0.02
2.069ThrTyr: 2.069 ± 0.037
0.0ThrXaa: 0.0 ± 0.0
Val
4.958ValAla: 4.958 ± 0.065
0.629ValCys: 0.629 ± 0.023
3.435ValAsp: 3.435 ± 0.053
5.103ValGlu: 5.103 ± 0.067
3.086ValPhe: 3.086 ± 0.051
5.001ValGly: 5.001 ± 0.059
1.445ValHis: 1.445 ± 0.033
5.418ValIle: 5.418 ± 0.066
4.884ValLys: 4.884 ± 0.056
6.835ValLeu: 6.835 ± 0.079
1.834ValMet: 1.834 ± 0.039
2.943ValAsn: 2.943 ± 0.05
2.649ValPro: 2.649 ± 0.042
2.454ValGln: 2.454 ± 0.04
2.637ValArg: 2.637 ± 0.046
4.666ValSer: 4.666 ± 0.049
4.186ValThr: 4.186 ± 0.108
5.133ValVal: 5.133 ± 0.064
0.631ValTrp: 0.631 ± 0.019
2.313ValTyr: 2.313 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
0.557TrpAla: 0.557 ± 0.019
0.097TrpCys: 0.097 ± 0.009
0.47TrpAsp: 0.47 ± 0.022
0.637TrpGlu: 0.637 ± 0.024
0.53TrpPhe: 0.53 ± 0.022
0.713TrpGly: 0.713 ± 0.025
0.214TrpHis: 0.214 ± 0.014
0.828TrpIle: 0.828 ± 0.027
0.767TrpLys: 0.767 ± 0.023
1.086TrpLeu: 1.086 ± 0.033
0.303TrpMet: 0.303 ± 0.015
0.552TrpAsn: 0.552 ± 0.019
0.243TrpPro: 0.243 ± 0.015
0.323TrpGln: 0.323 ± 0.016
0.424TrpArg: 0.424 ± 0.016
0.624TrpSer: 0.624 ± 0.022
0.533TrpThr: 0.533 ± 0.019
0.632TrpVal: 0.632 ± 0.02
0.149TrpTrp: 0.149 ± 0.01
0.31TrpTyr: 0.31 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.127TyrAla: 2.127 ± 0.041
0.317TyrCys: 0.317 ± 0.015
1.911TyrAsp: 1.911 ± 0.043
2.833TyrGlu: 2.833 ± 0.048
1.764TyrPhe: 1.764 ± 0.04
2.583TyrGly: 2.583 ± 0.043
0.844TyrHis: 0.844 ± 0.023
2.67TyrIle: 2.67 ± 0.052
2.477TyrLys: 2.477 ± 0.044
3.404TyrLeu: 3.404 ± 0.047
0.93TyrMet: 0.93 ± 0.023
1.649TyrAsn: 1.649 ± 0.042
1.393TyrPro: 1.393 ± 0.033
1.242TyrGln: 1.242 ± 0.032
1.654TyrArg: 1.654 ± 0.036
2.221TyrSer: 2.221 ± 0.037
1.918TyrThr: 1.918 ± 0.039
2.341TyrVal: 2.341 ± 0.044
0.378TyrTrp: 0.378 ± 0.018
1.476TyrTyr: 1.476 ± 0.037
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5042 proteins (1427216 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski