Amino acid dipepetide frequency for Hubei chuvirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.141AlaAla: 2.141 ± 1.22
0.612AlaCys: 0.612 ± 0.332
0.918AlaAsp: 0.918 ± 0.254
3.059AlaGlu: 3.059 ± 0.212
1.53AlaPhe: 1.53 ± 0.211
1.53AlaGly: 1.53 ± 1.349
0.612AlaHis: 0.612 ± 0.332
3.059AlaIle: 3.059 ± 0.976
1.53AlaLys: 1.53 ± 0.423
4.894AlaLeu: 4.894 ± 1.321
1.53AlaMet: 1.53 ± 0.211
0.612AlaAsn: 0.612 ± 0.332
1.53AlaPro: 1.53 ± 1.349
2.447AlaGln: 2.447 ± 0.873
1.835AlaArg: 1.835 ± 1.353
4.589AlaSer: 4.589 ± 0.985
1.224AlaThr: 1.224 ± 0.424
2.753AlaVal: 2.753 ± 0.528
0.306AlaTrp: 0.306 ± 0.514
2.447AlaTyr: 2.447 ± 1.75
0.0AlaXaa: 0.0 ± 0.0
Cys
0.612CysAla: 0.612 ± 0.425
0.306CysCys: 0.306 ± 0.166
0.918CysAsp: 0.918 ± 0.497
0.306CysGlu: 0.306 ± 0.166
0.306CysPhe: 0.306 ± 0.166
1.53CysGly: 1.53 ± 0.996
1.224CysHis: 1.224 ± 0.307
1.224CysIle: 1.224 ± 0.307
1.835CysLys: 1.835 ± 0.898
2.447CysLeu: 2.447 ± 0.613
0.0CysMet: 0.0 ± 0.0
1.224CysAsn: 1.224 ± 0.424
0.918CysPro: 0.918 ± 0.254
0.612CysGln: 0.612 ± 0.299
0.306CysArg: 0.306 ± 0.166
1.224CysSer: 1.224 ± 0.599
1.53CysThr: 1.53 ± 0.211
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.612CysTyr: 0.612 ± 0.299
0.0CysXaa: 0.0 ± 0.0
Asp
2.753AspAla: 2.753 ± 1.643
0.306AspCys: 0.306 ± 0.412
3.059AspAsp: 3.059 ± 0.555
3.365AspGlu: 3.365 ± 1.468
2.753AspPhe: 2.753 ± 1.033
2.447AspGly: 2.447 ± 0.364
1.53AspHis: 1.53 ± 0.829
4.283AspIle: 4.283 ± 1.339
2.141AspLys: 2.141 ± 0.538
5.506AspLeu: 5.506 ± 1.079
1.835AspMet: 1.835 ± 0.507
3.059AspAsn: 3.059 ± 1.323
1.53AspPro: 1.53 ± 0.211
1.53AspGln: 1.53 ± 0.845
0.612AspArg: 0.612 ± 0.332
1.53AspSer: 1.53 ± 0.423
3.059AspThr: 3.059 ± 1.195
1.835AspVal: 1.835 ± 0.898
0.0AspTrp: 0.0 ± 0.0
3.059AspTyr: 3.059 ± 1.017
0.0AspXaa: 0.0 ± 0.0
Glu
1.224GluAla: 1.224 ± 0.424
0.612GluCys: 0.612 ± 0.332
1.53GluAsp: 1.53 ± 0.829
2.141GluGlu: 2.141 ± 1.161
3.977GluPhe: 3.977 ± 1.174
1.835GluGly: 1.835 ± 0.995
0.0GluHis: 0.0 ± 0.0
3.365GluIle: 3.365 ± 0.363
3.365GluLys: 3.365 ± 0.983
8.871GluLeu: 8.871 ± 0.138
0.612GluMet: 0.612 ± 0.425
3.059GluAsn: 3.059 ± 0.812
0.918GluPro: 0.918 ± 0.497
2.141GluGln: 2.141 ± 0.716
3.365GluArg: 3.365 ± 0.626
5.2GluSer: 5.2 ± 0.439
4.283GluThr: 4.283 ± 0.68
2.141GluVal: 2.141 ± 0.622
0.306GluTrp: 0.306 ± 0.166
2.447GluTyr: 2.447 ± 0.193
0.0GluXaa: 0.0 ± 0.0
Phe
1.224PheAla: 1.224 ± 1.344
1.224PheCys: 1.224 ± 0.424
1.53PheAsp: 1.53 ± 0.512
2.753PheGlu: 2.753 ± 1.492
0.306PhePhe: 0.306 ± 0.166
2.447PheGly: 2.447 ± 0.613
0.918PheHis: 0.918 ± 0.254
4.283PheIle: 4.283 ± 1.433
3.059PheLys: 3.059 ± 0.683
5.2PheLeu: 5.2 ± 1.033
0.612PheMet: 0.612 ± 0.412
2.141PheAsn: 2.141 ± 0.769
1.53PhePro: 1.53 ± 0.845
0.918PheGln: 0.918 ± 0.497
2.753PheArg: 2.753 ± 1.033
3.671PheSer: 3.671 ± 1.128
2.447PheThr: 2.447 ± 1.198
2.753PheVal: 2.753 ± 0.521
0.0PheTrp: 0.0 ± 0.0
0.918PheTyr: 0.918 ± 0.391
0.0PheXaa: 0.0 ± 0.0
Gly
0.918GlyAla: 0.918 ± 0.928
0.918GlyCys: 0.918 ± 0.254
1.835GlyAsp: 1.835 ± 0.782
4.589GlyGlu: 4.589 ± 1.753
3.059GlyPhe: 3.059 ± 0.484
2.447GlyGly: 2.447 ± 0.364
1.53GlyHis: 1.53 ± 0.512
3.977GlyIle: 3.977 ± 0.413
2.141GlyLys: 2.141 ± 0.219
4.589GlyLeu: 4.589 ± 1.467
1.224GlyMet: 1.224 ± 0.825
2.753GlyAsn: 2.753 ± 1.643
1.224GlyPro: 1.224 ± 0.354
2.753GlyGln: 2.753 ± 0.559
2.753GlyArg: 2.753 ± 0.521
3.059GlySer: 3.059 ± 1.017
2.753GlyThr: 2.753 ± 1.153
2.447GlyVal: 2.447 ± 1.75
0.306GlyTrp: 0.306 ± 0.166
2.141GlyTyr: 2.141 ± 0.891
0.0GlyXaa: 0.0 ± 0.0
His
1.53HisAla: 1.53 ± 0.662
0.0HisCys: 0.0 ± 0.0
0.612HisAsp: 0.612 ± 0.425
0.306HisGlu: 0.306 ± 0.166
2.141HisPhe: 2.141 ± 0.219
0.918HisGly: 0.918 ± 0.497
1.53HisHis: 1.53 ± 0.829
2.447HisIle: 2.447 ± 0.364
1.53HisLys: 1.53 ± 0.512
3.365HisLeu: 3.365 ± 0.892
0.306HisMet: 0.306 ± 0.166
2.447HisAsn: 2.447 ± 0.873
1.224HisPro: 1.224 ± 0.307
0.918HisGln: 0.918 ± 0.497
0.306HisArg: 0.306 ± 0.514
1.835HisSer: 1.835 ± 0.138
1.224HisThr: 1.224 ± 1.111
1.53HisVal: 1.53 ± 0.211
0.306HisTrp: 0.306 ± 0.514
2.447HisTyr: 2.447 ± 0.873
0.0HisXaa: 0.0 ± 0.0
Ile
4.283IleAla: 4.283 ± 1.339
0.918IleCys: 0.918 ± 0.391
5.812IleAsp: 5.812 ± 0.899
6.118IleGlu: 6.118 ± 0.504
2.141IlePhe: 2.141 ± 0.769
4.283IleGly: 4.283 ± 0.978
2.447IleHis: 2.447 ± 0.613
7.954IleIle: 7.954 ± 1.641
6.73IleLys: 6.73 ± 1.741
10.095IleLeu: 10.095 ± 3.504
0.612IleMet: 0.612 ± 0.299
3.977IleAsn: 3.977 ± 1.174
3.671IlePro: 3.671 ± 0.522
3.671IleGln: 3.671 ± 1.35
3.059IleArg: 3.059 ± 0.683
4.894IleSer: 4.894 ± 1.279
4.283IleThr: 4.283 ± 1.149
4.589IleVal: 4.589 ± 2.012
0.306IleTrp: 0.306 ± 0.412
6.118IleTyr: 6.118 ± 1.566
0.0IleXaa: 0.0 ± 0.0
Lys
1.835LysAla: 1.835 ± 0.632
2.141LysCys: 2.141 ± 0.822
3.671LysAsp: 3.671 ± 1.128
3.059LysGlu: 3.059 ± 0.783
2.753LysPhe: 2.753 ± 0.528
0.918LysGly: 0.918 ± 0.497
1.835LysHis: 1.835 ± 0.723
6.118LysIle: 6.118 ± 0.949
1.224LysLys: 1.224 ± 1.359
5.506LysLeu: 5.506 ± 1.439
0.306LysMet: 0.306 ± 0.166
5.2LysAsn: 5.2 ± 0.925
1.224LysPro: 1.224 ± 0.663
2.141LysGln: 2.141 ± 0.822
1.835LysArg: 1.835 ± 1.626
3.671LysSer: 3.671 ± 0.275
6.424LysThr: 6.424 ± 2.149
2.753LysVal: 2.753 ± 1.033
1.224LysTrp: 1.224 ± 0.663
3.977LysTyr: 3.977 ± 1.302
0.0LysXaa: 0.0 ± 0.0
Leu
3.671LeuAla: 3.671 ± 0.275
1.53LeuCys: 1.53 ± 0.423
4.589LeuAsp: 4.589 ± 1.13
5.506LeuGlu: 5.506 ± 0.877
3.671LeuPhe: 3.671 ± 0.37
7.342LeuGly: 7.342 ± 1.821
2.753LeuHis: 2.753 ± 0.521
11.93LeuIle: 11.93 ± 1.537
4.894LeuLys: 4.894 ± 0.775
7.648LeuLeu: 7.648 ± 2.184
3.671LeuMet: 3.671 ± 1.303
7.036LeuAsn: 7.036 ± 1.493
5.812LeuPro: 5.812 ± 1.674
5.2LeuGln: 5.2 ± 0.439
8.565LeuArg: 8.565 ± 1.956
7.342LeuSer: 7.342 ± 2.576
7.648LeuThr: 7.648 ± 0.581
5.2LeuVal: 5.2 ± 1.59
1.224LeuTrp: 1.224 ± 0.424
6.73LeuTyr: 6.73 ± 0.823
0.0LeuXaa: 0.0 ± 0.0
Met
0.918MetAla: 0.918 ± 0.391
0.306MetCys: 0.306 ± 0.412
0.306MetAsp: 0.306 ± 0.412
0.612MetGlu: 0.612 ± 0.332
0.918MetPhe: 0.918 ± 0.511
1.53MetGly: 1.53 ± 0.845
0.0MetHis: 0.0 ± 0.0
2.447MetIle: 2.447 ± 0.774
0.918MetLys: 0.918 ± 0.391
2.447MetLeu: 2.447 ± 0.708
0.0MetMet: 0.0 ± 0.0
1.53MetAsn: 1.53 ± 1.522
0.306MetPro: 0.306 ± 0.166
1.224MetGln: 1.224 ± 0.85
1.224MetArg: 1.224 ± 0.663
2.447MetSer: 2.447 ± 0.774
2.753MetThr: 2.753 ± 0.528
0.612MetVal: 0.612 ± 0.332
0.0MetTrp: 0.0 ± 0.0
1.835MetTyr: 1.835 ± 1.044
0.0MetXaa: 0.0 ± 0.0
Asn
2.753AsnAla: 2.753 ± 0.559
1.835AsnCys: 1.835 ± 0.507
0.918AsnAsp: 0.918 ± 0.497
2.447AsnGlu: 2.447 ± 0.193
2.447AsnPhe: 2.447 ± 0.364
3.059AsnGly: 3.059 ± 2.807
2.447AsnHis: 2.447 ± 0.613
7.648AsnIle: 7.648 ± 3.204
2.447AsnLys: 2.447 ± 0.915
4.283AsnLeu: 4.283 ± 1.433
2.447AsnMet: 2.447 ± 0.193
7.036AsnAsn: 7.036 ± 1.631
4.589AsnPro: 4.589 ± 1.467
1.835AsnGln: 1.835 ± 1.022
3.365AsnArg: 3.365 ± 1.218
3.977AsnSer: 3.977 ± 0.838
3.671AsnThr: 3.671 ± 0.728
3.977AsnVal: 3.977 ± 0.912
0.918AsnTrp: 0.918 ± 0.511
4.283AsnTyr: 4.283 ± 0.849
0.0AsnXaa: 0.0 ± 0.0
Pro
1.53ProAla: 1.53 ± 0.662
0.306ProCys: 0.306 ± 0.166
2.753ProAsp: 2.753 ± 0.559
1.835ProGlu: 1.835 ± 0.138
1.835ProPhe: 1.835 ± 0.995
1.224ProGly: 1.224 ± 0.307
0.612ProHis: 0.612 ± 0.332
2.141ProIle: 2.141 ± 0.622
2.753ProLys: 2.753 ± 0.72
6.424ProLeu: 6.424 ± 0.803
0.306ProMet: 0.306 ± 0.166
4.283ProAsn: 4.283 ± 0.68
2.753ProPro: 2.753 ± 1.173
2.753ProGln: 2.753 ± 0.117
0.612ProArg: 0.612 ± 0.672
3.059ProSer: 3.059 ± 0.555
2.753ProThr: 2.753 ± 0.605
1.224ProVal: 1.224 ± 1.359
0.612ProTrp: 0.612 ± 0.425
2.141ProTyr: 2.141 ± 0.622
0.0ProXaa: 0.0 ± 0.0
Gln
2.141GlnAla: 2.141 ± 1.236
0.612GlnCys: 0.612 ± 0.299
1.224GlnAsp: 1.224 ± 0.663
2.753GlnGlu: 2.753 ± 1.492
0.612GlnPhe: 0.612 ± 0.299
3.059GlnGly: 3.059 ± 1.374
2.447GlnHis: 2.447 ± 1.198
3.671GlnIle: 3.671 ± 0.37
2.447GlnLys: 2.447 ± 0.873
5.506GlnLeu: 5.506 ± 1.956
1.224GlnMet: 1.224 ± 0.347
0.918GlnAsn: 0.918 ± 0.497
0.918GlnPro: 0.918 ± 0.99
2.753GlnGln: 2.753 ± 0.521
3.059GlnArg: 3.059 ± 0.845
2.447GlnSer: 2.447 ± 0.774
2.753GlnThr: 2.753 ± 0.559
2.141GlnVal: 2.141 ± 0.864
0.918GlnTrp: 0.918 ± 0.497
2.141GlnTyr: 2.141 ± 0.716
0.0GlnXaa: 0.0 ± 0.0
Arg
3.365ArgAla: 3.365 ± 1.468
0.306ArgCys: 0.306 ± 0.412
2.141ArgAsp: 2.141 ± 0.799
1.53ArgGlu: 1.53 ± 0.8
2.753ArgPhe: 2.753 ± 0.117
1.53ArgGly: 1.53 ± 0.512
1.53ArgHis: 1.53 ± 0.512
2.753ArgIle: 2.753 ± 0.117
3.671ArgLys: 3.671 ± 1.52
3.977ArgLeu: 3.977 ± 1.397
1.224ArgMet: 1.224 ± 0.663
2.141ArgAsn: 2.141 ± 0.716
2.447ArgPro: 2.447 ± 0.193
2.447ArgGln: 2.447 ± 1.185
2.753ArgArg: 2.753 ± 0.925
4.589ArgSer: 4.589 ± 0.578
2.141ArgThr: 2.141 ± 0.219
2.141ArgVal: 2.141 ± 0.799
0.918ArgTrp: 0.918 ± 0.391
1.53ArgTyr: 1.53 ± 0.211
0.0ArgXaa: 0.0 ± 0.0
Ser
0.612SerAla: 0.612 ± 0.332
1.835SerCys: 1.835 ± 0.507
3.977SerAsp: 3.977 ± 2.254
2.753SerGlu: 2.753 ± 1.033
4.589SerPhe: 4.589 ± 2.027
3.977SerGly: 3.977 ± 1.885
2.141SerHis: 2.141 ± 0.622
4.283SerIle: 4.283 ± 0.509
7.342SerLys: 7.342 ± 1.384
5.506SerLeu: 5.506 ± 0.971
0.612SerMet: 0.612 ± 0.425
6.118SerAsn: 6.118 ± 1.057
3.365SerPro: 3.365 ± 0.647
1.835SerGln: 1.835 ± 0.564
2.447SerArg: 2.447 ± 0.915
3.365SerSer: 3.365 ± 0.363
3.977SerThr: 3.977 ± 1.934
4.589SerVal: 4.589 ± 1.268
1.53SerTrp: 1.53 ± 0.53
3.977SerTyr: 3.977 ± 0.694
0.0SerXaa: 0.0 ± 0.0
Thr
2.447ThrAla: 2.447 ± 0.774
1.224ThrCys: 1.224 ± 0.599
3.365ThrAsp: 3.365 ± 0.933
3.671ThrGlu: 3.671 ± 0.275
1.224ThrPhe: 1.224 ± 0.424
1.53ThrGly: 1.53 ± 0.662
1.224ThrHis: 1.224 ± 0.98
4.589ThrIle: 4.589 ± 1.141
2.753ThrLys: 2.753 ± 0.528
10.707ThrLeu: 10.707 ± 2.113
1.224ThrMet: 1.224 ± 0.354
3.977ThrAsn: 3.977 ± 1.185
2.447ThrPro: 2.447 ± 0.613
1.835ThrGln: 1.835 ± 0.507
2.753ThrArg: 2.753 ± 1.033
3.977ThrSer: 3.977 ± 1.185
5.506ThrThr: 5.506 ± 1.831
3.671ThrVal: 3.671 ± 0.37
1.53ThrTrp: 1.53 ± 0.423
5.812ThrTyr: 5.812 ± 0.572
0.0ThrXaa: 0.0 ± 0.0
Val
2.447ValAla: 2.447 ± 1.185
0.918ValCys: 0.918 ± 0.497
2.753ValAsp: 2.753 ± 0.605
1.224ValGlu: 1.224 ± 0.354
2.141ValPhe: 2.141 ± 0.891
1.835ValGly: 1.835 ± 0.564
1.835ValHis: 1.835 ± 0.499
3.059ValIle: 3.059 ± 0.783
2.753ValLys: 2.753 ± 1.704
5.812ValLeu: 5.812 ± 0.864
1.53ValMet: 1.53 ± 0.172
3.671ValAsn: 3.671 ± 1.446
2.753ValPro: 2.753 ± 0.559
3.365ValGln: 3.365 ± 0.647
3.059ValArg: 3.059 ± 0.976
2.141ValSer: 2.141 ± 0.538
3.365ValThr: 3.365 ± 0.398
1.835ValVal: 1.835 ± 0.138
0.612ValTrp: 0.612 ± 0.332
3.059ValTyr: 3.059 ± 0.423
0.0ValXaa: 0.0 ± 0.0
Trp
0.612TrpAla: 0.612 ± 0.332
0.0TrpCys: 0.0 ± 0.0
0.612TrpAsp: 0.612 ± 0.425
1.224TrpGlu: 1.224 ± 0.307
0.918TrpPhe: 0.918 ± 0.511
0.612TrpGly: 0.612 ± 0.425
0.0TrpHis: 0.0 ± 0.0
0.306TrpIle: 0.306 ± 0.166
0.306TrpLys: 0.306 ± 0.166
0.918TrpLeu: 0.918 ± 0.497
0.306TrpMet: 0.306 ± 0.514
1.224TrpAsn: 1.224 ± 0.354
0.918TrpPro: 0.918 ± 0.391
0.918TrpGln: 0.918 ± 0.701
0.612TrpArg: 0.612 ± 0.332
0.918TrpSer: 0.918 ± 0.254
0.918TrpThr: 0.918 ± 0.497
0.306TrpVal: 0.306 ± 0.166
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.141TyrAla: 2.141 ± 0.769
1.224TyrCys: 1.224 ± 0.354
3.671TyrAsp: 3.671 ± 0.92
2.141TyrGlu: 2.141 ± 1.161
0.918TyrPhe: 0.918 ± 0.497
3.365TyrGly: 3.365 ± 1.644
0.306TyrHis: 0.306 ± 0.166
6.424TyrIle: 6.424 ± 1.528
3.977TyrLys: 3.977 ± 0.315
8.259TyrLeu: 8.259 ± 1.486
2.447TyrMet: 2.447 ± 1.295
3.977TyrAsn: 3.977 ± 0.912
1.835TyrPro: 1.835 ± 1.022
2.447TyrGln: 2.447 ± 1.198
0.612TyrArg: 0.612 ± 0.332
4.894TyrSer: 4.894 ± 0.652
2.753TyrThr: 2.753 ± 1.487
3.671TyrVal: 3.671 ± 1.062
0.612TyrTrp: 0.612 ± 0.299
3.365TyrTyr: 3.365 ± 0.316
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski