Amino acid dipepetide frequency for Pseudomonas xinjiangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.983AlaAla: 11.983 ± 0.135	1.169AlaCys: 1.169 ± 0.036	6.11AlaAsp: 6.11 ± 0.086	7.465AlaGlu: 7.465 ± 0.092	3.59AlaPhe: 3.59 ± 0.062	9.311AlaGly: 9.311 ± 0.123	2.047AlaHis: 2.047 ± 0.044	5.164AlaIle: 5.164 ± 0.064	2.962AlaLys: 2.962 ± 0.057	12.568AlaLeu: 12.568 ± 0.138	3.015AlaMet: 3.015 ± 0.053	2.915AlaAsn: 2.915 ± 0.052	4.272AlaPro: 4.272 ± 0.069	4.418AlaGln: 4.418 ± 0.078	7.334AlaArg: 7.334 ± 0.092	6.225AlaSer: 6.225 ± 0.08	4.857AlaThr: 4.857 ± 0.07	7.6AlaVal: 7.6 ± 0.077	1.56AlaTrp: 1.56 ± 0.04	2.361AlaTyr: 2.361 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.007CysAla: 1.007 ± 0.035	0.142CysCys: 0.142 ± 0.011	0.54CysAsp: 0.54 ± 0.024	0.58CysGlu: 0.58 ± 0.024	0.352CysPhe: 0.352 ± 0.018	0.927CysGly: 0.927 ± 0.033	0.271CysHis: 0.271 ± 0.018	0.46CysIle: 0.46 ± 0.023	0.267CysLys: 0.267 ± 0.015	1.102CysLeu: 1.102 ± 0.03	0.217CysMet: 0.217 ± 0.013	0.248CysAsn: 0.248 ± 0.016	0.481CysPro: 0.481 ± 0.023	0.414CysGln: 0.414 ± 0.023	0.672CysArg: 0.672 ± 0.025	0.597CysSer: 0.597 ± 0.023	0.451CysThr: 0.451 ± 0.023	0.657CysVal: 0.657 ± 0.023	0.143CysTrp: 0.143 ± 0.012	0.238CysTyr: 0.238 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.8AspAla: 5.8 ± 0.083	0.543AspCys: 0.543 ± 0.023	3.175AspAsp: 3.175 ± 0.063	3.976AspGlu: 3.976 ± 0.07	2.059AspPhe: 2.059 ± 0.042	4.432AspGly: 4.432 ± 0.073	1.194AspHis: 1.194 ± 0.038	3.02AspIle: 3.02 ± 0.051	1.78AspLys: 1.78 ± 0.037	5.962AspLeu: 5.962 ± 0.081	1.515AspMet: 1.515 ± 0.039	1.586AspAsn: 1.586 ± 0.044	3.068AspPro: 3.068 ± 0.054	2.465AspGln: 2.465 ± 0.041	3.761AspArg: 3.761 ± 0.055	3.103AspSer: 3.103 ± 0.055	2.706AspThr: 2.706 ± 0.054	4.117AspVal: 4.117 ± 0.07	0.987AspTrp: 0.987 ± 0.032	1.69AspTyr: 1.69 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.054GluAla: 7.054 ± 0.097	0.459GluCys: 0.459 ± 0.023	2.936GluAsp: 2.936 ± 0.042	3.716GluGlu: 3.716 ± 0.069	1.875GluPhe: 1.875 ± 0.044	4.263GluGly: 4.263 ± 0.066	1.725GluHis: 1.725 ± 0.037	2.922GluIle: 2.922 ± 0.052	2.115GluLys: 2.115 ± 0.046	7.195GluLeu: 7.195 ± 0.096	1.532GluMet: 1.532 ± 0.038	1.643GluAsn: 1.643 ± 0.041	3.074GluPro: 3.074 ± 0.062	4.023GluGln: 4.023 ± 0.074	5.341GluArg: 5.341 ± 0.084	3.184GluSer: 3.184 ± 0.057	3.065GluThr: 3.065 ± 0.053	4.304GluVal: 4.304 ± 0.074	0.811GluTrp: 0.811 ± 0.031	1.338GluTyr: 1.338 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.884PheAla: 3.884 ± 0.067	0.416PheCys: 0.416 ± 0.02	2.438PheAsp: 2.438 ± 0.044	2.214PheGlu: 2.214 ± 0.04	1.404PhePhe: 1.404 ± 0.043	3.127PheGly: 3.127 ± 0.056	0.767PheHis: 0.767 ± 0.03	1.827PheIle: 1.827 ± 0.043	1.049PheLys: 1.049 ± 0.033	3.186PheLeu: 3.186 ± 0.061	0.922PheMet: 0.922 ± 0.029	1.228PheAsn: 1.228 ± 0.038	1.43PhePro: 1.43 ± 0.036	1.086PheGln: 1.086 ± 0.031	2.011PheArg: 2.011 ± 0.048	2.32PheSer: 2.32 ± 0.047	1.93PheThr: 1.93 ± 0.044	2.56PheVal: 2.56 ± 0.047	0.525PheTrp: 0.525 ± 0.027	1.046PheTyr: 1.046 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	7.211GlyAla: 7.211 ± 0.101	0.999GlyCys: 0.999 ± 0.033	4.236GlyAsp: 4.236 ± 0.068	5.107GlyGlu: 5.107 ± 0.076	3.303GlyPhe: 3.303 ± 0.057	6.085GlyGly: 6.085 ± 0.116	1.869GlyHis: 1.869 ± 0.046	4.183GlyIle: 4.183 ± 0.065	2.983GlyLys: 2.983 ± 0.063	9.075GlyLeu: 9.075 ± 0.121	2.492GlyMet: 2.492 ± 0.053	2.315GlyAsn: 2.315 ± 0.053	2.798GlyPro: 2.798 ± 0.058	3.387GlyGln: 3.387 ± 0.057	5.323GlyArg: 5.323 ± 0.079	4.78GlySer: 4.78 ± 0.08	3.971GlyThr: 3.971 ± 0.072	5.921GlyVal: 5.921 ± 0.076	1.357GlyTrp: 1.357 ± 0.038	2.516GlyTyr: 2.516 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.208HisAla: 2.208 ± 0.045	0.314HisCys: 0.314 ± 0.017	1.275HisAsp: 1.275 ± 0.035	1.203HisGlu: 1.203 ± 0.037	0.931HisPhe: 0.931 ± 0.031	1.931HisGly: 1.931 ± 0.048	0.643HisHis: 0.643 ± 0.025	1.073HisIle: 1.073 ± 0.029	0.584HisLys: 0.584 ± 0.024	2.334HisLeu: 2.334 ± 0.046	0.577HisMet: 0.577 ± 0.022	0.646HisAsn: 0.646 ± 0.023	1.406HisPro: 1.406 ± 0.035	0.899HisGln: 0.899 ± 0.033	1.523HisArg: 1.523 ± 0.042	1.288HisSer: 1.288 ± 0.035	0.991HisThr: 0.991 ± 0.028	1.414HisVal: 1.414 ± 0.039	0.352HisTrp: 0.352 ± 0.019	0.703HisTyr: 0.703 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.765IleAla: 5.765 ± 0.087	0.505IleCys: 0.505 ± 0.021	3.562IleAsp: 3.562 ± 0.059	3.693IleGlu: 3.693 ± 0.061	1.506IlePhe: 1.506 ± 0.041	4.53IleGly: 4.53 ± 0.084	0.971IleHis: 0.971 ± 0.031	2.367IleIle: 2.367 ± 0.052	1.608IleLys: 1.608 ± 0.046	4.217IleLeu: 4.217 ± 0.076	0.984IleMet: 0.984 ± 0.035	1.798IleAsn: 1.798 ± 0.039	2.307IlePro: 2.307 ± 0.049	1.632IleGln: 1.632 ± 0.041	3.189IleArg: 3.189 ± 0.053	2.885IleSer: 2.885 ± 0.052	2.622IleThr: 2.622 ± 0.05	3.513IleVal: 3.513 ± 0.064	0.539IleTrp: 0.539 ± 0.023	1.063IleTyr: 1.063 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.366LysAla: 3.366 ± 0.069	0.172LysCys: 0.172 ± 0.013	1.507LysAsp: 1.507 ± 0.044	1.575LysGlu: 1.575 ± 0.043	0.744LysPhe: 0.744 ± 0.028	2.287LysGly: 2.287 ± 0.06	0.72LysHis: 0.72 ± 0.026	1.362LysIle: 1.362 ± 0.04	1.105LysLys: 1.105 ± 0.045	3.339LysLeu: 3.339 ± 0.064	0.657LysMet: 0.657 ± 0.025	0.821LysAsn: 0.821 ± 0.027	1.919LysPro: 1.919 ± 0.045	1.47LysGln: 1.47 ± 0.038	2.402LysArg: 2.402 ± 0.05	1.589LysSer: 1.589 ± 0.045	1.553LysThr: 1.553 ± 0.038	2.477LysVal: 2.477 ± 0.055	0.318LysTrp: 0.318 ± 0.017	0.603LysTyr: 0.603 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.407LeuAla: 13.407 ± 0.143	1.148LeuCys: 1.148 ± 0.033	6.936LeuAsp: 6.936 ± 0.088	6.734LeuGlu: 6.734 ± 0.094	3.94LeuPhe: 3.94 ± 0.075	9.02LeuGly: 9.02 ± 0.094	2.29LeuHis: 2.29 ± 0.047	5.494LeuIle: 5.494 ± 0.088	3.539LeuLys: 3.539 ± 0.064	12.418LeuLeu: 12.418 ± 0.179	2.626LeuMet: 2.626 ± 0.045	3.202LeuAsn: 3.202 ± 0.056	5.965LeuPro: 5.965 ± 0.077	4.275LeuGln: 4.275 ± 0.067	7.595LeuArg: 7.595 ± 0.089	6.751LeuSer: 6.751 ± 0.089	5.588LeuThr: 5.588 ± 0.082	8.068LeuVal: 8.068 ± 0.11	1.364LeuTrp: 1.364 ± 0.046	2.471LeuTyr: 2.471 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.745MetAla: 2.745 ± 0.05	0.189MetCys: 0.189 ± 0.013	1.236MetAsp: 1.236 ± 0.033	1.131MetGlu: 1.131 ± 0.035	0.751MetPhe: 0.751 ± 0.028	1.858MetGly: 1.858 ± 0.042	0.602MetHis: 0.602 ± 0.025	1.275MetIle: 1.275 ± 0.032	0.888MetLys: 0.888 ± 0.032	3.076MetLeu: 3.076 ± 0.058	0.58MetMet: 0.58 ± 0.026	0.87MetAsn: 0.87 ± 0.028	1.435MetPro: 1.435 ± 0.032	1.279MetGln: 1.279 ± 0.036	1.693MetArg: 1.693 ± 0.039	1.784MetSer: 1.784 ± 0.038	1.603MetThr: 1.603 ± 0.039	1.771MetVal: 1.771 ± 0.039	0.212MetTrp: 0.212 ± 0.014	0.448MetTyr: 0.448 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.927AsnAla: 2.927 ± 0.062	0.274AsnCys: 0.274 ± 0.016	1.586AsnAsp: 1.586 ± 0.038	1.635AsnGlu: 1.635 ± 0.045	0.938AsnPhe: 0.938 ± 0.027	2.304AsnGly: 2.304 ± 0.045	0.626AsnHis: 0.626 ± 0.021	1.474AsnIle: 1.474 ± 0.041	0.814AsnLys: 0.814 ± 0.029	3.173AsnLeu: 3.173 ± 0.06	0.665AsnMet: 0.665 ± 0.023	0.867AsnAsn: 0.867 ± 0.033	1.9AsnPro: 1.9 ± 0.042	1.342AsnGln: 1.342 ± 0.037	2.064AsnArg: 2.064 ± 0.048	1.47AsnSer: 1.47 ± 0.036	1.475AsnThr: 1.475 ± 0.037	1.93AsnVal: 1.93 ± 0.042	0.429AsnTrp: 0.429 ± 0.023	0.756AsnTyr: 0.756 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.433ProAla: 5.433 ± 0.082	0.344ProCys: 0.344 ± 0.02	3.315ProAsp: 3.315 ± 0.059	3.784ProGlu: 3.784 ± 0.071	1.749ProPhe: 1.749 ± 0.04	4.31ProGly: 4.31 ± 0.063	0.984ProHis: 0.984 ± 0.031	2.079ProIle: 2.079 ± 0.041	1.242ProLys: 1.242 ± 0.036	5.248ProLeu: 5.248 ± 0.074	1.283ProMet: 1.283 ± 0.035	1.253ProAsn: 1.253 ± 0.038	2.072ProPro: 2.072 ± 0.05	1.94ProGln: 1.94 ± 0.044	2.678ProArg: 2.678 ± 0.057	2.581ProSer: 2.581 ± 0.049	2.226ProThr: 2.226 ± 0.048	4.09ProVal: 4.09 ± 0.071	0.72ProTrp: 0.72 ± 0.028	1.128ProTyr: 1.128 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	5.629GlnAla: 5.629 ± 0.087	0.313GlnCys: 0.313 ± 0.018	1.846GlnAsp: 1.846 ± 0.044	2.028GlnGlu: 2.028 ± 0.05	1.293GlnPhe: 1.293 ± 0.034	3.106GlnGly: 3.106 ± 0.056	1.067GlnHis: 1.067 ± 0.031	1.983GlnIle: 1.983 ± 0.046	1.094GlnLys: 1.094 ± 0.039	5.132GlnLeu: 5.132 ± 0.076	1.042GlnMet: 1.042 ± 0.031	1.031GlnAsn: 1.031 ± 0.029	2.505GlnPro: 2.505 ± 0.059	2.563GlnGln: 2.563 ± 0.056	3.705GlnArg: 3.705 ± 0.057	2.376GlnSer: 2.376 ± 0.056	2.08GlnThr: 2.08 ± 0.049	3.246GlnVal: 3.246 ± 0.062	0.647GlnTrp: 0.647 ± 0.029	0.964GlnTyr: 0.964 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	6.188ArgAla: 6.188 ± 0.077	0.649ArgCys: 0.649 ± 0.024	4.039ArgAsp: 4.039 ± 0.063	4.505ArgGlu: 4.505 ± 0.065	2.953ArgPhe: 2.953 ± 0.054	4.38ArgGly: 4.38 ± 0.061	1.757ArgHis: 1.757 ± 0.046	3.652ArgIle: 3.652 ± 0.062	2.144ArgLys: 2.144 ± 0.049	8.497ArgLeu: 8.497 ± 0.106	1.819ArgMet: 1.819 ± 0.039	2.049ArgAsn: 2.049 ± 0.043	3.014ArgPro: 3.014 ± 0.051	3.557ArgGln: 3.557 ± 0.072	4.893ArgArg: 4.893 ± 0.088	3.964ArgSer: 3.964 ± 0.06	3.067ArgThr: 3.067 ± 0.056	4.846ArgVal: 4.846 ± 0.074	1.172ArgTrp: 1.172 ± 0.03	2.184ArgTyr: 2.184 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.958SerAla: 5.958 ± 0.081	0.499SerCys: 0.499 ± 0.022	3.085SerAsp: 3.085 ± 0.058	3.597SerGlu: 3.597 ± 0.053	2.119SerPhe: 2.119 ± 0.045	5.306SerGly: 5.306 ± 0.074	1.259SerHis: 1.259 ± 0.035	2.865SerIle: 2.865 ± 0.056	1.562SerLys: 1.562 ± 0.039	6.775SerLeu: 6.775 ± 0.096	1.584SerMet: 1.584 ± 0.041	1.636SerAsn: 1.636 ± 0.044	2.61SerPro: 2.61 ± 0.049	2.374SerGln: 2.374 ± 0.048	3.901SerArg: 3.901 ± 0.058	3.483SerSer: 3.483 ± 0.072	2.798SerThr: 2.798 ± 0.063	4.149SerVal: 4.149 ± 0.067	0.877SerTrp: 0.877 ± 0.028	1.383SerTyr: 1.383 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.116ThrAla: 5.116 ± 0.079	0.395ThrCys: 0.395 ± 0.019	2.811ThrAsp: 2.811 ± 0.054	2.778ThrGlu: 2.778 ± 0.054	1.746ThrPhe: 1.746 ± 0.042	4.621ThrGly: 4.621 ± 0.082	1.043ThrHis: 1.043 ± 0.028	2.317ThrIle: 2.317 ± 0.049	1.033ThrLys: 1.033 ± 0.034	6.456ThrLeu: 6.456 ± 0.086	1.005ThrMet: 1.005 ± 0.03	1.236ThrAsn: 1.236 ± 0.033	2.824ThrPro: 2.824 ± 0.055	1.9ThrGln: 1.9 ± 0.042	3.305ThrArg: 3.305 ± 0.051	2.721ThrSer: 2.721 ± 0.066	2.362ThrThr: 2.362 ± 0.052	3.656ThrVal: 3.656 ± 0.054	0.653ThrTrp: 0.653 ± 0.027	1.144ThrTyr: 1.144 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.727ValAla: 7.727 ± 0.088	0.767ValCys: 0.767 ± 0.026	4.306ValAsp: 4.306 ± 0.07	4.846ValGlu: 4.846 ± 0.074	2.563ValPhe: 2.563 ± 0.056	5.259ValGly: 5.259 ± 0.074	1.471ValHis: 1.471 ± 0.043	4.025ValIle: 4.025 ± 0.071	2.133ValLys: 2.133 ± 0.055	8.025ValLeu: 8.025 ± 0.103	1.976ValMet: 1.976 ± 0.047	2.221ValAsn: 2.221 ± 0.048	3.408ValPro: 3.408 ± 0.063	2.56ValGln: 2.56 ± 0.056	4.69ValArg: 4.69 ± 0.073	4.423ValSer: 4.423 ± 0.061	3.973ValThr: 3.973 ± 0.06	5.721ValVal: 5.721 ± 0.088	0.941ValTrp: 0.941 ± 0.035	1.651ValTyr: 1.651 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.129TrpAla: 1.129 ± 0.035	0.16TrpCys: 0.16 ± 0.01	0.635TrpAsp: 0.635 ± 0.025	0.666TrpGlu: 0.666 ± 0.026	0.551TrpPhe: 0.551 ± 0.025	0.877TrpGly: 0.877 ± 0.032	0.396TrpHis: 0.396 ± 0.02	0.702TrpIle: 0.702 ± 0.028	0.401TrpLys: 0.401 ± 0.022	2.243TrpLeu: 2.243 ± 0.058	0.408TrpMet: 0.408 ± 0.018	0.418TrpAsn: 0.418 ± 0.018	0.701TrpPro: 0.701 ± 0.028	0.841TrpGln: 0.841 ± 0.031	1.119TrpArg: 1.119 ± 0.033	0.78TrpSer: 0.78 ± 0.029	0.628TrpThr: 0.628 ± 0.024	0.987TrpVal: 0.987 ± 0.032	0.227TrpTrp: 0.227 ± 0.018	0.364TrpTyr: 0.364 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.39TyrAla: 2.39 ± 0.041	0.31TyrCys: 0.31 ± 0.018	1.365TyrAsp: 1.365 ± 0.038	1.342TyrGlu: 1.342 ± 0.036	1.002TyrPhe: 1.002 ± 0.035	1.977TyrGly: 1.977 ± 0.042	0.593TyrHis: 0.593 ± 0.024	1.007TyrIle: 1.007 ± 0.033	0.68TyrLys: 0.68 ± 0.027	2.811TyrLeu: 2.811 ± 0.055	0.528TyrMet: 0.528 ± 0.025	0.668TyrAsn: 0.668 ± 0.027	1.271TyrPro: 1.271 ± 0.039	1.224TyrGln: 1.224 ± 0.032	2.131TyrArg: 2.131 ± 0.046	1.517TyrSer: 1.517 ± 0.037	1.176TyrThr: 1.176 ± 0.033	1.66TyrVal: 1.66 ± 0.036	0.399TyrTrp: 0.399 ± 0.02	0.716TyrTyr: 0.716 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3245 proteins (1066341 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---