Amino acid dipepetide frequency for Changjiang crawfish virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.816AlaAla: 8.816 ± 0.821
1.259AlaCys: 1.259 ± 0.756
3.778AlaAsp: 3.778 ± 0.025
3.778AlaGlu: 3.778 ± 1.504
2.939AlaPhe: 2.939 ± 1.293
8.816AlaGly: 8.816 ± 1.585
1.679AlaHis: 1.679 ± 0.244
3.778AlaIle: 3.778 ± 0.74
2.519AlaLys: 2.519 ± 0.748
7.137AlaLeu: 7.137 ± 1.065
2.519AlaMet: 2.519 ± 0.016
3.359AlaAsn: 3.359 ± 3.333
4.198AlaPro: 4.198 ± 0.537
1.679AlaGln: 1.679 ± 0.52
4.198AlaArg: 4.198 ± 1.301
5.877AlaSer: 5.877 ± 1.057
5.458AlaThr: 5.458 ± 2.837
8.816AlaVal: 8.816 ± 1.471
2.099AlaTrp: 2.099 ± 0.268
2.939AlaTyr: 2.939 ± 0.528
0.0AlaXaa: 0.0 ± 0.0
Cys
0.42CysAla: 0.42 ± 0.252
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.84CysGlu: 0.84 ± 0.504
1.679CysPhe: 1.679 ± 0.52
1.259CysGly: 1.259 ± 0.008
0.0CysHis: 0.0 ± 0.0
0.84CysIle: 0.84 ± 0.504
0.84CysLys: 0.84 ± 0.504
0.42CysLeu: 0.42 ± 0.252
0.42CysMet: 0.42 ± 0.252
0.0CysAsn: 0.0 ± 0.0
1.259CysPro: 1.259 ± 0.756
0.42CysGln: 0.42 ± 0.252
0.42CysArg: 0.42 ± 0.512
0.42CysSer: 0.42 ± 0.252
0.0CysThr: 0.0 ± 0.0
0.42CysVal: 0.42 ± 0.252
0.0CysTrp: 0.0 ± 0.0
0.84CysTyr: 0.84 ± 0.26
0.0CysXaa: 0.0 ± 0.0
Asp
3.359AspAla: 3.359 ± 1.252
1.679AspCys: 1.679 ± 1.008
2.939AspAsp: 2.939 ± 0.236
3.359AspGlu: 3.359 ± 0.488
2.939AspPhe: 2.939 ± 0.236
3.359AspGly: 3.359 ± 1.805
0.42AspHis: 0.42 ± 0.252
2.939AspIle: 2.939 ± 1.0
2.939AspLys: 2.939 ± 1.0
7.976AspLeu: 7.976 ± 0.561
2.519AspMet: 2.519 ± 0.016
2.099AspAsn: 2.099 ± 0.268
1.679AspPro: 1.679 ± 1.008
1.679AspGln: 1.679 ± 0.52
1.679AspArg: 1.679 ± 0.244
1.679AspSer: 1.679 ± 1.008
3.778AspThr: 3.778 ± 0.025
4.198AspVal: 4.198 ± 0.537
1.259AspTrp: 1.259 ± 0.756
2.099AspTyr: 2.099 ± 0.268
0.0AspXaa: 0.0 ± 0.0
Glu
4.618GluAla: 4.618 ± 0.285
0.0GluCys: 0.0 ± 0.0
2.939GluAsp: 2.939 ± 1.0
2.519GluGlu: 2.519 ± 1.512
2.519GluPhe: 2.519 ± 0.016
2.099GluGly: 2.099 ± 1.26
1.259GluHis: 1.259 ± 0.756
2.519GluIle: 2.519 ± 0.016
1.679GluLys: 1.679 ± 1.008
6.717GluLeu: 6.717 ± 0.211
1.259GluMet: 1.259 ± 0.772
1.679GluAsn: 1.679 ± 1.008
1.679GluPro: 1.679 ± 1.008
1.679GluGln: 1.679 ± 1.008
1.259GluArg: 1.259 ± 0.008
4.198GluSer: 4.198 ± 0.537
4.198GluThr: 4.198 ± 2.52
1.259GluVal: 1.259 ± 0.756
1.259GluTrp: 1.259 ± 0.756
3.359GluTyr: 3.359 ± 0.488
0.0GluXaa: 0.0 ± 0.0
Phe
3.359PheAla: 3.359 ± 1.805
0.42PheCys: 0.42 ± 0.252
3.778PheAsp: 3.778 ± 0.74
1.679PheGlu: 1.679 ± 0.52
2.099PhePhe: 2.099 ± 0.268
5.038PheGly: 5.038 ± 0.797
0.84PheHis: 0.84 ± 1.024
2.519PheIle: 2.519 ± 0.748
2.519PheLys: 2.519 ± 0.78
2.519PheLeu: 2.519 ± 1.512
0.84PheMet: 0.84 ± 0.639
1.259PheAsn: 1.259 ± 0.008
2.519PhePro: 2.519 ± 0.78
2.939PheGln: 2.939 ± 0.528
3.778PheArg: 3.778 ± 3.845
2.099PheSer: 2.099 ± 1.032
2.519PheThr: 2.519 ± 0.016
3.778PheVal: 3.778 ± 1.553
0.84PheTrp: 0.84 ± 0.26
0.42PheTyr: 0.42 ± 0.512
0.0PheXaa: 0.0 ± 0.0
Gly
6.297GlyAla: 6.297 ± 2.333
0.84GlyCys: 0.84 ± 0.504
6.717GlyAsp: 6.717 ± 1.739
2.939GlyGlu: 2.939 ± 0.528
2.519GlyPhe: 2.519 ± 0.78
7.137GlyGly: 7.137 ± 0.463
0.84GlyHis: 0.84 ± 0.26
2.519GlyIle: 2.519 ± 0.748
2.519GlyLys: 2.519 ± 0.748
5.458GlyLeu: 5.458 ± 0.983
1.679GlyMet: 1.679 ± 0.244
2.519GlyAsn: 2.519 ± 0.016
3.778GlyPro: 3.778 ± 2.317
1.259GlyGln: 1.259 ± 0.008
2.939GlyArg: 2.939 ± 0.236
9.656GlySer: 9.656 ± 3.374
6.297GlyThr: 6.297 ± 1.569
5.877GlyVal: 5.877 ± 1.235
0.84GlyTrp: 0.84 ± 0.504
2.519GlyTyr: 2.519 ± 0.748
0.0GlyXaa: 0.0 ± 0.0
His
1.259HisAla: 1.259 ± 0.772
0.0HisCys: 0.0 ± 0.0
1.679HisAsp: 1.679 ± 0.244
0.84HisGlu: 0.84 ± 0.504
1.679HisPhe: 1.679 ± 0.244
0.42HisGly: 0.42 ± 0.512
0.0HisHis: 0.0 ± 0.0
1.259HisIle: 1.259 ± 0.772
1.259HisLys: 1.259 ± 0.756
2.519HisLeu: 2.519 ± 0.748
0.42HisMet: 0.42 ± 0.512
0.84HisAsn: 0.84 ± 0.504
1.679HisPro: 1.679 ± 0.244
0.42HisGln: 0.42 ± 0.512
0.0HisArg: 0.0 ± 0.0
1.259HisSer: 1.259 ± 0.756
1.259HisThr: 1.259 ± 0.008
2.519HisVal: 2.519 ± 0.016
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.198IleAla: 4.198 ± 1.301
0.0IleCys: 0.0 ± 0.0
2.939IleAsp: 2.939 ± 1.293
2.099IleGlu: 2.099 ± 0.496
0.84IlePhe: 0.84 ± 0.26
5.458IleGly: 5.458 ± 0.545
0.84IleHis: 0.84 ± 0.504
3.359IleIle: 3.359 ± 1.252
2.099IleLys: 2.099 ± 1.26
4.198IleLeu: 4.198 ± 2.52
1.679IleMet: 1.679 ± 1.032
1.679IleAsn: 1.679 ± 1.008
3.778IlePro: 3.778 ± 0.789
0.42IleGln: 0.42 ± 0.252
2.099IleArg: 2.099 ± 0.496
3.778IleSer: 3.778 ± 0.025
3.359IleThr: 3.359 ± 1.252
2.519IleVal: 2.519 ± 0.016
0.42IleTrp: 0.42 ± 0.252
2.099IleTyr: 2.099 ± 1.032
0.0IleXaa: 0.0 ± 0.0
Lys
4.618LysAla: 4.618 ± 0.479
0.84LysCys: 0.84 ± 0.504
3.778LysAsp: 3.778 ± 1.504
2.519LysGlu: 2.519 ± 0.016
1.679LysPhe: 1.679 ± 0.244
3.778LysGly: 3.778 ± 1.504
0.0LysHis: 0.0 ± 0.0
1.259LysIle: 1.259 ± 0.756
5.038LysLys: 5.038 ± 3.024
5.458LysLeu: 5.458 ± 1.747
1.259LysMet: 1.259 ± 0.008
1.679LysAsn: 1.679 ± 0.52
2.099LysPro: 2.099 ± 0.268
2.099LysGln: 2.099 ± 0.496
2.939LysArg: 2.939 ± 0.236
4.618LysSer: 4.618 ± 1.244
3.778LysThr: 3.778 ± 1.504
4.198LysVal: 4.198 ± 0.227
1.259LysTrp: 1.259 ± 0.756
1.259LysTyr: 1.259 ± 0.756
0.0LysXaa: 0.0 ± 0.0
Leu
8.816LeuAla: 8.816 ± 2.235
1.679LeuCys: 1.679 ± 1.284
6.297LeuAsp: 6.297 ± 0.041
5.038LeuGlu: 5.038 ± 0.731
1.259LeuPhe: 1.259 ± 0.008
5.877LeuGly: 5.877 ± 1.999
1.679LeuHis: 1.679 ± 1.008
2.519LeuIle: 2.519 ± 0.016
7.137LeuLys: 7.137 ± 1.991
6.717LeuLeu: 6.717 ± 1.739
2.519LeuMet: 2.519 ± 0.748
4.198LeuAsn: 4.198 ± 1.756
5.038LeuPro: 5.038 ± 0.033
2.939LeuGln: 2.939 ± 1.0
3.359LeuArg: 3.359 ± 1.041
5.458LeuSer: 5.458 ± 2.073
7.557LeuThr: 7.557 ± 0.813
5.458LeuVal: 5.458 ± 0.219
2.519LeuTrp: 2.519 ± 1.512
2.519LeuTyr: 2.519 ± 0.016
0.0LeuXaa: 0.0 ± 0.0
Met
4.198MetAla: 4.198 ± 1.756
0.0MetCys: 0.0 ± 0.0
2.939MetAsp: 2.939 ± 0.236
0.84MetGlu: 0.84 ± 0.504
1.679MetPhe: 1.679 ± 0.244
0.84MetGly: 0.84 ± 0.26
1.259MetHis: 1.259 ± 1.536
1.679MetIle: 1.679 ± 0.244
1.679MetLys: 1.679 ± 0.244
0.84MetLeu: 0.84 ± 1.024
1.679MetMet: 1.679 ± 0.244
1.679MetAsn: 1.679 ± 1.008
0.84MetPro: 0.84 ± 0.26
0.84MetGln: 0.84 ± 0.26
2.939MetArg: 2.939 ± 1.0
2.099MetSer: 2.099 ± 0.496
1.259MetThr: 1.259 ± 0.772
1.679MetVal: 1.679 ± 1.284
0.42MetTrp: 0.42 ± 0.252
1.259MetTyr: 1.259 ± 0.756
0.0MetXaa: 0.0 ± 0.0
Asn
2.939AsnAla: 2.939 ± 1.293
0.42AsnCys: 0.42 ± 0.512
1.679AsnAsp: 1.679 ± 1.008
1.259AsnGlu: 1.259 ± 0.772
1.679AsnPhe: 1.679 ± 0.52
2.519AsnGly: 2.519 ± 0.78
0.0AsnHis: 0.0 ± 0.0
3.359AsnIle: 3.359 ± 1.252
0.42AsnLys: 0.42 ± 0.252
2.099AsnLeu: 2.099 ± 0.268
0.42AsnMet: 0.42 ± 0.252
2.519AsnAsn: 2.519 ± 1.545
2.099AsnPro: 2.099 ± 1.032
1.679AsnGln: 1.679 ± 0.244
2.519AsnArg: 2.519 ± 1.512
5.038AsnSer: 5.038 ± 2.325
1.679AsnThr: 1.679 ± 0.244
1.679AsnVal: 1.679 ± 0.244
0.42AsnTrp: 0.42 ± 0.252
1.679AsnTyr: 1.679 ± 0.244
0.0AsnXaa: 0.0 ± 0.0
Pro
3.359ProAla: 3.359 ± 0.277
0.42ProCys: 0.42 ± 0.252
2.519ProAsp: 2.519 ± 0.78
2.519ProGlu: 2.519 ± 1.512
5.038ProPhe: 5.038 ± 4.617
2.939ProGly: 2.939 ± 0.528
1.679ProHis: 1.679 ± 0.52
1.259ProIle: 1.259 ± 1.536
2.099ProLys: 2.099 ± 0.496
5.458ProLeu: 5.458 ± 0.983
1.679ProMet: 1.679 ± 0.244
1.259ProAsn: 1.259 ± 0.008
2.519ProPro: 2.519 ± 0.016
0.42ProGln: 0.42 ± 0.252
1.679ProArg: 1.679 ± 1.008
4.198ProSer: 4.198 ± 0.537
2.939ProThr: 2.939 ± 1.293
3.778ProVal: 3.778 ± 0.789
1.679ProTrp: 1.679 ± 0.244
2.519ProTyr: 2.519 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
3.778GlnAla: 3.778 ± 0.025
0.0GlnCys: 0.0 ± 0.0
1.259GlnAsp: 1.259 ± 0.008
1.259GlnGlu: 1.259 ± 0.756
1.259GlnPhe: 1.259 ± 0.756
1.679GlnGly: 1.679 ± 0.52
2.099GlnHis: 2.099 ± 0.496
0.84GlnIle: 0.84 ± 0.26
2.099GlnLys: 2.099 ± 1.26
1.679GlnLeu: 1.679 ± 1.008
0.42GlnMet: 0.42 ± 0.252
0.84GlnAsn: 0.84 ± 0.26
0.84GlnPro: 0.84 ± 0.504
1.259GlnGln: 1.259 ± 0.756
0.84GlnArg: 0.84 ± 0.504
2.939GlnSer: 2.939 ± 0.528
0.84GlnThr: 0.84 ± 1.024
2.519GlnVal: 2.519 ± 0.016
0.84GlnTrp: 0.84 ± 0.504
1.679GlnTyr: 1.679 ± 0.52
0.0GlnXaa: 0.0 ± 0.0
Arg
3.778ArgAla: 3.778 ± 0.025
0.42ArgCys: 0.42 ± 0.252
1.259ArgAsp: 1.259 ± 0.008
2.939ArgGlu: 2.939 ± 1.764
2.519ArgPhe: 2.519 ± 0.016
3.778ArgGly: 3.778 ± 0.025
1.259ArgHis: 1.259 ± 0.008
2.099ArgIle: 2.099 ± 0.496
2.099ArgLys: 2.099 ± 0.268
5.038ArgLeu: 5.038 ± 0.797
2.519ArgMet: 2.519 ± 0.016
0.84ArgAsn: 0.84 ± 0.26
2.099ArgPro: 2.099 ± 0.268
0.42ArgGln: 0.42 ± 0.252
3.359ArgArg: 3.359 ± 0.488
2.519ArgSer: 2.519 ± 1.512
3.359ArgThr: 3.359 ± 2.016
2.939ArgVal: 2.939 ± 2.821
0.0ArgTrp: 0.0 ± 0.0
3.778ArgTyr: 3.778 ± 0.025
0.0ArgXaa: 0.0 ± 0.0
Ser
6.297SerAla: 6.297 ± 3.861
0.0SerCys: 0.0 ± 0.0
2.099SerAsp: 2.099 ± 0.268
4.618SerGlu: 4.618 ± 0.479
3.359SerPhe: 3.359 ± 1.805
6.717SerGly: 6.717 ± 2.845
0.84SerHis: 0.84 ± 0.26
4.198SerIle: 4.198 ± 1.301
4.198SerLys: 4.198 ± 1.301
7.137SerLeu: 7.137 ± 1.227
2.099SerMet: 2.099 ± 0.496
2.939SerAsn: 2.939 ± 1.764
3.778SerPro: 3.778 ± 0.789
2.099SerGln: 2.099 ± 0.496
3.778SerArg: 3.778 ± 0.025
5.877SerSer: 5.877 ± 1.057
6.717SerThr: 6.717 ± 5.138
7.137SerVal: 7.137 ± 0.463
1.259SerTrp: 1.259 ± 0.756
0.84SerTyr: 0.84 ± 0.26
0.0SerXaa: 0.0 ± 0.0
Thr
3.778ThrAla: 3.778 ± 0.025
0.0ThrCys: 0.0 ± 0.0
3.359ThrAsp: 3.359 ± 1.041
1.679ThrGlu: 1.679 ± 0.244
2.099ThrPhe: 2.099 ± 0.496
3.778ThrGly: 3.778 ± 0.74
1.679ThrHis: 1.679 ± 1.008
5.038ThrIle: 5.038 ± 0.797
4.618ThrLys: 4.618 ± 1.244
5.877ThrLeu: 5.877 ± 1.821
2.099ThrMet: 2.099 ± 0.268
3.359ThrAsn: 3.359 ± 2.569
3.778ThrPro: 3.778 ± 0.025
2.099ThrGln: 2.099 ± 0.268
2.939ThrArg: 2.939 ± 0.236
6.717ThrSer: 6.717 ± 2.845
4.198ThrThr: 4.198 ± 0.227
6.297ThrVal: 6.297 ± 0.041
0.0ThrTrp: 0.0 ± 0.0
3.359ThrTyr: 3.359 ± 1.041
0.0ThrXaa: 0.0 ± 0.0
Val
7.557ValAla: 7.557 ± 1.577
1.679ValCys: 1.679 ± 0.244
2.519ValAsp: 2.519 ± 0.748
5.038ValGlu: 5.038 ± 1.495
3.359ValPhe: 3.359 ± 0.277
5.458ValGly: 5.458 ± 0.983
1.679ValHis: 1.679 ± 1.008
2.519ValIle: 2.519 ± 0.78
5.038ValLys: 5.038 ± 0.731
6.717ValLeu: 6.717 ± 1.739
2.939ValMet: 2.939 ± 1.0
2.519ValAsn: 2.519 ± 1.545
3.778ValPro: 3.778 ± 2.317
2.939ValGln: 2.939 ± 0.236
3.778ValArg: 3.778 ± 2.268
5.458ValSer: 5.458 ± 3.601
3.359ValThr: 3.359 ± 1.041
7.557ValVal: 7.557 ± 0.049
0.84ValTrp: 0.84 ± 1.024
3.359ValTyr: 3.359 ± 1.041
0.0ValXaa: 0.0 ± 0.0
Trp
0.42TrpAla: 0.42 ± 0.252
0.42TrpCys: 0.42 ± 0.252
0.84TrpAsp: 0.84 ± 0.504
1.259TrpGlu: 1.259 ± 0.756
2.099TrpPhe: 2.099 ± 1.797
0.84TrpGly: 0.84 ± 0.504
0.42TrpHis: 0.42 ± 0.252
1.259TrpIle: 1.259 ± 0.756
0.42TrpLys: 0.42 ± 0.252
2.519TrpLeu: 2.519 ± 0.748
0.0TrpMet: 0.0 ± 0.0
0.42TrpAsn: 0.42 ± 0.252
0.0TrpPro: 0.0 ± 0.0
1.259TrpGln: 1.259 ± 0.756
1.679TrpArg: 1.679 ± 0.244
0.84TrpSer: 0.84 ± 0.504
0.84TrpThr: 0.84 ± 0.26
1.259TrpVal: 1.259 ± 0.756
0.0TrpTrp: 0.0 ± 0.0
0.84TrpTyr: 0.84 ± 0.504
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.778TyrAla: 3.778 ± 1.553
0.42TyrCys: 0.42 ± 0.252
1.259TyrAsp: 1.259 ± 0.008
1.679TyrGlu: 1.679 ± 0.244
2.939TyrPhe: 2.939 ± 0.236
3.359TyrGly: 3.359 ± 0.277
0.84TyrHis: 0.84 ± 1.024
2.099TyrIle: 2.099 ± 0.268
2.939TyrLys: 2.939 ± 1.0
2.099TyrLeu: 2.099 ± 0.268
1.259TyrMet: 1.259 ± 0.008
0.42TyrAsn: 0.42 ± 0.512
2.519TyrPro: 2.519 ± 0.78
0.42TyrGln: 0.42 ± 0.252
0.84TyrArg: 0.84 ± 0.504
1.259TyrSer: 1.259 ± 0.008
3.359TyrThr: 3.359 ± 0.488
4.198TyrVal: 4.198 ± 1.301
1.679TyrTrp: 1.679 ± 0.244
1.259TyrTyr: 1.259 ± 0.772
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2383 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski