Amino acid dipepetide frequency for Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 / KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040) (Corynebacterium paurometabolum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
23.134AlaAla: 23.134 ± 0.463
0.9AlaCys: 0.9 ± 0.026
8.799AlaAsp: 8.799 ± 0.172
8.111AlaGlu: 8.111 ± 0.095
3.672AlaPhe: 3.672 ± 0.055
12.575AlaGly: 12.575 ± 0.113
2.444AlaHis: 2.444 ± 0.047
5.472AlaIle: 5.472 ± 0.077
3.144AlaLys: 3.144 ± 0.073
13.688AlaLeu: 13.688 ± 0.14
2.788AlaMet: 2.788 ± 0.046
2.411AlaAsn: 2.411 ± 0.045
7.445AlaPro: 7.445 ± 0.101
4.192AlaGln: 4.192 ± 0.072
9.521AlaArg: 9.521 ± 0.104
6.286AlaSer: 6.286 ± 0.074
7.899AlaThr: 7.899 ± 0.114
12.577AlaVal: 12.577 ± 0.138
1.692AlaTrp: 1.692 ± 0.035
2.413AlaTyr: 2.413 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.963CysAla: 0.963 ± 0.028
0.072CysCys: 0.072 ± 0.007
0.402CysAsp: 0.402 ± 0.017
0.332CysGlu: 0.332 ± 0.016
0.203CysPhe: 0.203 ± 0.013
0.858CysGly: 0.858 ± 0.027
0.13CysHis: 0.13 ± 0.01
0.226CysIle: 0.226 ± 0.013
0.094CysLys: 0.094 ± 0.008
0.545CysLeu: 0.545 ± 0.02
0.102CysMet: 0.102 ± 0.01
0.139CysAsn: 0.139 ± 0.01
0.354CysPro: 0.354 ± 0.019
0.145CysGln: 0.145 ± 0.011
0.452CysArg: 0.452 ± 0.02
0.419CysSer: 0.419 ± 0.017
0.452CysThr: 0.452 ± 0.021
0.537CysVal: 0.537 ± 0.02
0.088CysTrp: 0.088 ± 0.009
0.156CysTyr: 0.156 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
8.263AspAla: 8.263 ± 0.102
0.352AspCys: 0.352 ± 0.017
4.083AspAsp: 4.083 ± 0.07
4.149AspGlu: 4.149 ± 0.055
1.776AspPhe: 1.776 ± 0.034
6.496AspGly: 6.496 ± 0.077
1.305AspHis: 1.305 ± 0.036
2.191AspIle: 2.191 ± 0.046
1.241AspLys: 1.241 ± 0.053
6.233AspLeu: 6.233 ± 0.067
0.904AspMet: 0.904 ± 0.025
0.966AspAsn: 0.966 ± 0.031
4.432AspPro: 4.432 ± 0.061
1.662AspGln: 1.662 ± 0.032
4.945AspArg: 4.945 ± 0.072
2.741AspSer: 2.741 ± 0.049
3.119AspThr: 3.119 ± 0.047
5.156AspVal: 5.156 ± 0.059
0.864AspTrp: 0.864 ± 0.027
1.327AspTyr: 1.327 ± 0.036
0.0AspXaa: 0.0 ± 0.0
Glu
6.565GluAla: 6.565 ± 0.095
0.294GluCys: 0.294 ± 0.014
2.333GluAsp: 2.333 ± 0.047
2.439GluGlu: 2.439 ± 0.048
1.819GluPhe: 1.819 ± 0.041
3.492GluGly: 3.492 ± 0.057
1.376GluHis: 1.376 ± 0.037
2.496GluIle: 2.496 ± 0.04
1.51GluLys: 1.51 ± 0.042
6.124GluLeu: 6.124 ± 0.079
0.896GluMet: 0.896 ± 0.025
1.231GluAsn: 1.231 ± 0.033
2.915GluPro: 2.915 ± 0.05
2.167GluGln: 2.167 ± 0.05
4.739GluArg: 4.739 ± 0.071
2.87GluSer: 2.87 ± 0.042
2.718GluThr: 2.718 ± 0.048
4.518GluVal: 4.518 ± 0.062
0.731GluTrp: 0.731 ± 0.023
1.182GluTyr: 1.182 ± 0.031
0.0GluXaa: 0.0 ± 0.0
Phe
4.263PheAla: 4.263 ± 0.063
0.258PheCys: 0.258 ± 0.012
2.371PheAsp: 2.371 ± 0.038
1.462PheGlu: 1.462 ± 0.036
0.966PhePhe: 0.966 ± 0.027
3.479PheGly: 3.479 ± 0.048
0.554PheHis: 0.554 ± 0.021
0.957PheIle: 0.957 ± 0.029
0.474PheLys: 0.474 ± 0.021
2.741PheLeu: 2.741 ± 0.046
0.43PheMet: 0.43 ± 0.017
0.561PheAsn: 0.561 ± 0.022
1.456PhePro: 1.456 ± 0.033
0.649PheGln: 0.649 ± 0.022
1.726PheArg: 1.726 ± 0.035
1.675PheSer: 1.675 ± 0.038
2.105PheThr: 2.105 ± 0.042
2.55PheVal: 2.55 ± 0.048
0.424PheTrp: 0.424 ± 0.021
0.651PheTyr: 0.651 ± 0.023
0.0PheXaa: 0.0 ± 0.0
Gly
11.873GlyAla: 11.873 ± 0.128
0.688GlyCys: 0.688 ± 0.027
5.132GlyAsp: 5.132 ± 0.068
4.693GlyGlu: 4.693 ± 0.059
3.14GlyPhe: 3.14 ± 0.046
8.3GlyGly: 8.3 ± 0.097
1.907GlyHis: 1.907 ± 0.042
4.23GlyIle: 4.23 ± 0.059
2.34GlyLys: 2.34 ± 0.043
8.941GlyLeu: 8.941 ± 0.095
1.984GlyMet: 1.984 ± 0.041
1.766GlyAsn: 1.766 ± 0.041
4.701GlyPro: 4.701 ± 0.061
2.481GlyGln: 2.481 ± 0.049
6.475GlyArg: 6.475 ± 0.075
5.107GlySer: 5.107 ± 0.07
6.002GlyThr: 6.002 ± 0.071
7.999GlyVal: 7.999 ± 0.091
1.562GlyTrp: 1.562 ± 0.037
2.452GlyTyr: 2.452 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.308HisAla: 2.308 ± 0.044
0.174HisCys: 0.174 ± 0.013
1.231HisAsp: 1.231 ± 0.031
0.982HisGlu: 0.982 ± 0.026
0.566HisPhe: 0.566 ± 0.021
1.915HisGly: 1.915 ± 0.036
0.567HisHis: 0.567 ± 0.023
0.668HisIle: 0.668 ± 0.026
0.304HisLys: 0.304 ± 0.015
2.026HisLeu: 2.026 ± 0.038
0.302HisMet: 0.302 ± 0.015
0.367HisAsn: 0.367 ± 0.016
1.518HisPro: 1.518 ± 0.036
0.506HisGln: 0.506 ± 0.018
1.788HisArg: 1.788 ± 0.044
0.914HisSer: 0.914 ± 0.025
1.095HisThr: 1.095 ± 0.032
1.577HisVal: 1.577 ± 0.036
0.314HisTrp: 0.314 ± 0.014
0.442HisTyr: 0.442 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
6.945IleAla: 6.945 ± 0.081
0.272IleCys: 0.272 ± 0.015
3.422IleAsp: 3.422 ± 0.053
2.547IleGlu: 2.547 ± 0.051
0.988IlePhe: 0.988 ± 0.027
4.599IleGly: 4.599 ± 0.072
0.635IleHis: 0.635 ± 0.021
1.41IleIle: 1.41 ± 0.042
0.89IleLys: 0.89 ± 0.026
3.173IleLeu: 3.173 ± 0.045
0.568IleMet: 0.568 ± 0.02
0.938IleAsn: 0.938 ± 0.026
2.185IlePro: 2.185 ± 0.037
0.707IleGln: 0.707 ± 0.021
2.581IleArg: 2.581 ± 0.047
2.188IleSer: 2.188 ± 0.038
2.867IleThr: 2.867 ± 0.048
3.875IleVal: 3.875 ± 0.055
0.402IleTrp: 0.402 ± 0.019
0.668IleTyr: 0.668 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
2.847LysAla: 2.847 ± 0.092
0.101LysCys: 0.101 ± 0.009
1.27LysAsp: 1.27 ± 0.036
0.96LysGlu: 0.96 ± 0.032
0.616LysPhe: 0.616 ± 0.025
1.601LysGly: 1.601 ± 0.037
0.44LysHis: 0.44 ± 0.016
1.021LysIle: 1.021 ± 0.028
0.756LysLys: 0.756 ± 0.037
2.046LysLeu: 2.046 ± 0.044
0.463LysMet: 0.463 ± 0.017
0.633LysAsn: 0.633 ± 0.024
1.388LysPro: 1.388 ± 0.04
0.843LysGln: 0.843 ± 0.028
1.521LysArg: 1.521 ± 0.038
1.273LysSer: 1.273 ± 0.035
1.325LysThr: 1.325 ± 0.04
1.954LysVal: 1.954 ± 0.048
0.279LysTrp: 0.279 ± 0.016
0.551LysTyr: 0.551 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
14.264LeuAla: 14.264 ± 0.137
0.691LeuCys: 0.691 ± 0.021
6.56LeuAsp: 6.56 ± 0.077
4.13LeuGlu: 4.13 ± 0.059
2.647LeuPhe: 2.647 ± 0.054
9.107LeuGly: 9.107 ± 0.093
1.864LeuHis: 1.864 ± 0.039
4.12LeuIle: 4.12 ± 0.062
1.73LeuLys: 1.73 ± 0.035
9.667LeuLeu: 9.667 ± 0.102
1.677LeuMet: 1.677 ± 0.035
1.74LeuAsn: 1.74 ± 0.04
5.759LeuPro: 5.759 ± 0.074
2.417LeuGln: 2.417 ± 0.043
7.718LeuArg: 7.718 ± 0.097
5.292LeuSer: 5.292 ± 0.063
6.528LeuThr: 6.528 ± 0.071
8.658LeuVal: 8.658 ± 0.097
1.209LeuTrp: 1.209 ± 0.034
1.664LeuTyr: 1.664 ± 0.036
0.0LeuXaa: 0.0 ± 0.0
Met
2.288MetAla: 2.288 ± 0.039
0.139MetCys: 0.139 ± 0.011
0.825MetAsp: 0.825 ± 0.023
0.681MetGlu: 0.681 ± 0.026
0.608MetPhe: 0.608 ± 0.024
1.374MetGly: 1.374 ± 0.035
0.36MetHis: 0.36 ± 0.018
0.875MetIle: 0.875 ± 0.029
0.421MetLys: 0.421 ± 0.016
1.794MetLeu: 1.794 ± 0.036
0.378MetMet: 0.378 ± 0.02
0.534MetAsn: 0.534 ± 0.02
1.083MetPro: 1.083 ± 0.031
0.506MetGln: 0.506 ± 0.021
1.395MetArg: 1.395 ± 0.034
1.472MetSer: 1.472 ± 0.033
1.809MetThr: 1.809 ± 0.036
1.469MetVal: 1.469 ± 0.033
0.221MetTrp: 0.221 ± 0.011
0.348MetTyr: 0.348 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.463AsnAla: 2.463 ± 0.054
0.144AsnCys: 0.144 ± 0.01
1.042AsnAsp: 1.042 ± 0.032
0.948AsnGlu: 0.948 ± 0.027
0.554AsnPhe: 0.554 ± 0.021
1.887AsnGly: 1.887 ± 0.043
0.387AsnHis: 0.387 ± 0.018
0.8AsnIle: 0.8 ± 0.028
0.49AsnLys: 0.49 ± 0.018
2.0AsnLeu: 2.0 ± 0.041
0.368AsnMet: 0.368 ± 0.017
0.498AsnAsn: 0.498 ± 0.023
1.691AsnPro: 1.691 ± 0.044
0.589AsnGln: 0.589 ± 0.022
1.477AsnArg: 1.477 ± 0.03
1.007AsnSer: 1.007 ± 0.025
1.241AsnThr: 1.241 ± 0.036
1.609AsnVal: 1.609 ± 0.034
0.294AsnTrp: 0.294 ± 0.015
0.477AsnTyr: 0.477 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
8.02ProAla: 8.02 ± 0.099
0.247ProCys: 0.247 ± 0.014
4.339ProAsp: 4.339 ± 0.062
3.78ProGlu: 3.78 ± 0.051
1.59ProPhe: 1.59 ± 0.033
6.02ProGly: 6.02 ± 0.08
1.102ProHis: 1.102 ± 0.032
2.061ProIle: 2.061 ± 0.041
1.357ProLys: 1.357 ± 0.04
4.761ProLeu: 4.761 ± 0.066
1.004ProMet: 1.004 ± 0.031
1.209ProAsn: 1.209 ± 0.034
2.94ProPro: 2.94 ± 0.07
1.829ProGln: 1.829 ± 0.04
3.665ProArg: 3.665 ± 0.057
3.342ProSer: 3.342 ± 0.057
3.429ProThr: 3.429 ± 0.051
5.152ProVal: 5.152 ± 0.07
0.819ProTrp: 0.819 ± 0.025
1.094ProTyr: 1.094 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
3.573GlnAla: 3.573 ± 0.068
0.17GlnCys: 0.17 ± 0.012
1.159GlnAsp: 1.159 ± 0.028
1.188GlnGlu: 1.188 ± 0.031
0.813GlnPhe: 0.813 ± 0.025
2.077GlnGly: 2.077 ± 0.046
0.615GlnHis: 0.615 ± 0.024
1.342GlnIle: 1.342 ± 0.033
0.665GlnLys: 0.665 ± 0.024
2.962GlnLeu: 2.962 ± 0.051
0.58GlnMet: 0.58 ± 0.021
0.629GlnAsn: 0.629 ± 0.026
1.645GlnPro: 1.645 ± 0.045
1.226GlnGln: 1.226 ± 0.038
2.49GlnArg: 2.49 ± 0.047
1.426GlnSer: 1.426 ± 0.032
1.436GlnThr: 1.436 ± 0.033
2.561GlnVal: 2.561 ± 0.041
0.526GlnTrp: 0.526 ± 0.018
0.691GlnTyr: 0.691 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
9.241ArgAla: 9.241 ± 0.11
0.428ArgCys: 0.428 ± 0.019
4.396ArgAsp: 4.396 ± 0.067
4.211ArgGlu: 4.211 ± 0.057
2.488ArgPhe: 2.488 ± 0.047
5.683ArgGly: 5.683 ± 0.068
1.511ArgHis: 1.511 ± 0.034
3.661ArgIle: 3.661 ± 0.053
1.554ArgLys: 1.554 ± 0.04
7.086ArgLeu: 7.086 ± 0.088
1.72ArgMet: 1.72 ± 0.034
1.481ArgAsn: 1.481 ± 0.039
4.098ArgPro: 4.098 ± 0.073
1.834ArgGln: 1.834 ± 0.038
6.675ArgArg: 6.675 ± 0.094
4.283ArgSer: 4.283 ± 0.059
4.745ArgThr: 4.745 ± 0.063
5.718ArgVal: 5.718 ± 0.069
1.27ArgTrp: 1.27 ± 0.035
1.795ArgTyr: 1.795 ± 0.032
0.0ArgXaa: 0.0 ± 0.0
Ser
7.219SerAla: 7.219 ± 0.084
0.343SerCys: 0.343 ± 0.017
3.12SerAsp: 3.12 ± 0.047
2.578SerGlu: 2.578 ± 0.046
1.539SerPhe: 1.539 ± 0.036
5.806SerGly: 5.806 ± 0.067
0.843SerHis: 0.843 ± 0.026
2.273SerIle: 2.273 ± 0.037
1.238SerLys: 1.238 ± 0.034
4.799SerLeu: 4.799 ± 0.07
1.249SerMet: 1.249 ± 0.032
1.065SerAsn: 1.065 ± 0.028
3.053SerPro: 3.053 ± 0.047
1.311SerGln: 1.311 ± 0.034
3.5SerArg: 3.5 ± 0.057
3.229SerSer: 3.229 ± 0.064
3.553SerThr: 3.553 ± 0.056
4.695SerVal: 4.695 ± 0.06
0.84SerTrp: 0.84 ± 0.029
1.131SerTyr: 1.131 ± 0.029
0.0SerXaa: 0.0 ± 0.0
Thr
8.694ThrAla: 8.694 ± 0.117
0.39ThrCys: 0.39 ± 0.016
3.941ThrAsp: 3.941 ± 0.05
3.213ThrGlu: 3.213 ± 0.046
1.731ThrPhe: 1.731 ± 0.037
6.191ThrGly: 6.191 ± 0.074
1.065ThrHis: 1.065 ± 0.029
2.395ThrIle: 2.395 ± 0.042
1.325ThrLys: 1.325 ± 0.041
5.593ThrLeu: 5.593 ± 0.069
1.103ThrMet: 1.103 ± 0.026
1.124ThrAsn: 1.124 ± 0.03
4.035ThrPro: 4.035 ± 0.064
1.396ThrGln: 1.396 ± 0.031
3.784ThrArg: 3.784 ± 0.055
3.189ThrSer: 3.189 ± 0.05
3.84ThrThr: 3.84 ± 0.066
7.151ThrVal: 7.151 ± 0.077
0.817ThrTrp: 0.817 ± 0.025
1.212ThrTyr: 1.212 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
12.102ValAla: 12.102 ± 0.113
0.697ValCys: 0.697 ± 0.023
5.712ValAsp: 5.712 ± 0.064
4.357ValGlu: 4.357 ± 0.052
2.695ValPhe: 2.695 ± 0.052
7.331ValGly: 7.331 ± 0.079
1.799ValHis: 1.799 ± 0.04
4.334ValIle: 4.334 ± 0.058
1.667ValLys: 1.667 ± 0.041
9.366ValLeu: 9.366 ± 0.108
1.493ValMet: 1.493 ± 0.036
1.86ValAsn: 1.86 ± 0.039
5.185ValPro: 5.185 ± 0.07
2.211ValGln: 2.211 ± 0.045
6.346ValArg: 6.346 ± 0.077
4.669ValSer: 4.669 ± 0.063
5.943ValThr: 5.943 ± 0.072
8.498ValVal: 8.498 ± 0.105
1.068ValTrp: 1.068 ± 0.033
1.635ValTyr: 1.635 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.536TrpAla: 1.536 ± 0.038
0.124TrpCys: 0.124 ± 0.01
0.755TrpAsp: 0.755 ± 0.024
0.632TrpGlu: 0.632 ± 0.022
0.552TrpPhe: 0.552 ± 0.024
1.026TrpGly: 1.026 ± 0.03
0.322TrpHis: 0.322 ± 0.015
0.691TrpIle: 0.691 ± 0.021
0.327TrpLys: 0.327 ± 0.017
1.524TrpLeu: 1.524 ± 0.039
0.319TrpMet: 0.319 ± 0.015
0.396TrpAsn: 0.396 ± 0.018
0.689TrpPro: 0.689 ± 0.022
0.498TrpGln: 0.498 ± 0.02
1.209TrpArg: 1.209 ± 0.029
0.891TrpSer: 0.891 ± 0.025
0.837TrpThr: 0.837 ± 0.028
1.112TrpVal: 1.112 ± 0.032
0.342TrpTrp: 0.342 ± 0.017
0.322TrpTyr: 0.322 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.601TyrAla: 2.601 ± 0.05
0.187TyrCys: 0.187 ± 0.012
1.314TyrAsp: 1.314 ± 0.039
1.019TyrGlu: 1.019 ± 0.032
0.788TyrPhe: 0.788 ± 0.025
1.956TyrGly: 1.956 ± 0.039
0.336TyrHis: 0.336 ± 0.016
0.634TyrIle: 0.634 ± 0.023
0.363TyrLys: 0.363 ± 0.015
2.376TyrLeu: 2.376 ± 0.045
0.247TyrMet: 0.247 ± 0.015
0.417TyrAsn: 0.417 ± 0.019
1.188TyrPro: 1.188 ± 0.028
0.607TyrGln: 0.607 ± 0.023
1.874TyrArg: 1.874 ± 0.037
1.114TyrSer: 1.114 ± 0.031
1.246TyrThr: 1.246 ± 0.035
1.598TyrVal: 1.598 ± 0.036
0.345TyrTrp: 0.345 ± 0.018
0.463TyrTyr: 0.463 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4170 proteins (1342153 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski