Amino acid dipepetide frequency for Beihai picorna-like virus 93

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.213AlaAla: 8.213 ± 0.297
1.971AlaCys: 1.971 ± 1.071
3.614AlaAsp: 3.614 ± 0.681
3.285AlaGlu: 3.285 ± 0.33
3.285AlaPhe: 3.285 ± 0.33
6.57AlaGly: 6.57 ± 0.397
1.314AlaHis: 1.314 ± 0.714
3.942AlaIle: 3.942 ± 1.613
3.285AlaLys: 3.285 ± 0.199
6.899AlaLeu: 6.899 ± 0.576
0.329AlaMet: 0.329 ± 0.179
2.957AlaAsn: 2.957 ± 0.509
5.913AlaPro: 5.913 ± 0.489
1.314AlaGln: 1.314 ± 0.185
4.271AlaArg: 4.271 ± 0.205
5.585AlaSer: 5.585 ± 0.138
4.599AlaThr: 4.599 ± 0.913
4.599AlaVal: 4.599 ± 1.203
0.657AlaTrp: 0.657 ± 0.701
0.329AlaTyr: 0.329 ± 0.179
0.0AlaXaa: 0.0 ± 0.0
Cys
2.3CysAla: 2.3 ± 0.721
1.314CysCys: 1.314 ± 0.185
1.643CysAsp: 1.643 ± 0.893
0.986CysGlu: 0.986 ± 0.536
0.986CysPhe: 0.986 ± 0.536
2.3CysGly: 2.3 ± 0.721
0.0CysHis: 0.0 ± 0.0
1.643CysIle: 1.643 ± 0.364
1.643CysLys: 1.643 ± 0.165
1.643CysLeu: 1.643 ± 0.364
0.657CysMet: 0.657 ± 0.357
0.329CysAsn: 0.329 ± 0.179
0.986CysPro: 0.986 ± 0.007
0.329CysGln: 0.329 ± 0.179
1.643CysArg: 1.643 ± 0.364
1.643CysSer: 1.643 ± 0.893
0.986CysThr: 0.986 ± 0.536
2.3CysVal: 2.3 ± 1.25
0.0CysTrp: 0.0 ± 0.0
0.657CysTyr: 0.657 ± 0.357
0.0CysXaa: 0.0 ± 0.0
Asp
4.599AspAla: 4.599 ± 1.441
0.986AspCys: 0.986 ± 0.536
3.942AspAsp: 3.942 ± 0.027
1.643AspGlu: 1.643 ± 0.165
3.285AspPhe: 3.285 ± 0.199
3.942AspGly: 3.942 ± 0.556
1.643AspHis: 1.643 ± 0.364
4.928AspIle: 4.928 ± 0.495
2.957AspLys: 2.957 ± 1.078
5.585AspLeu: 5.585 ± 1.448
0.329AspMet: 0.329 ± 0.179
2.3AspAsn: 2.3 ± 0.337
3.285AspPro: 3.285 ± 0.859
2.3AspGln: 2.3 ± 1.395
1.643AspArg: 1.643 ± 0.165
3.942AspSer: 3.942 ± 1.56
3.614AspThr: 3.614 ± 0.681
6.57AspVal: 6.57 ± 0.661
1.314AspTrp: 1.314 ± 0.714
1.643AspTyr: 1.643 ± 0.694
0.0AspXaa: 0.0 ± 0.0
Glu
4.928GluAla: 4.928 ± 0.562
1.971GluCys: 1.971 ± 1.071
3.614GluAsp: 3.614 ± 0.906
1.314GluGlu: 1.314 ± 0.872
1.971GluPhe: 1.971 ± 1.044
1.643GluGly: 1.643 ± 0.694
1.643GluHis: 1.643 ± 0.364
3.285GluIle: 3.285 ± 0.199
1.643GluLys: 1.643 ± 0.165
2.3GluLeu: 2.3 ± 0.721
1.643GluMet: 1.643 ± 0.165
2.3GluAsn: 2.3 ± 0.866
1.643GluPro: 1.643 ± 1.223
1.643GluGln: 1.643 ± 0.165
2.628GluArg: 2.628 ± 0.37
3.614GluSer: 3.614 ± 0.377
2.3GluThr: 2.3 ± 0.721
3.285GluVal: 3.285 ± 0.859
0.329GluTrp: 0.329 ± 0.179
3.285GluTyr: 3.285 ± 0.199
0.0GluXaa: 0.0 ± 0.0
Phe
4.271PheAla: 4.271 ± 1.381
0.986PheCys: 0.986 ± 0.007
3.285PheAsp: 3.285 ± 0.33
1.314PheGlu: 1.314 ± 0.714
2.628PhePhe: 2.628 ± 0.37
2.628PheGly: 2.628 ± 0.37
0.986PheHis: 0.986 ± 0.007
2.628PheIle: 2.628 ± 0.37
0.657PheLys: 0.657 ± 0.357
2.628PheLeu: 2.628 ± 0.158
1.643PheMet: 1.643 ± 0.694
2.3PheAsn: 2.3 ± 0.337
3.614PhePro: 3.614 ± 1.209
1.971PheGln: 1.971 ± 0.515
0.986PheArg: 0.986 ± 0.536
7.227PheSer: 7.227 ± 0.754
1.314PheThr: 1.314 ± 0.872
3.942PheVal: 3.942 ± 0.556
0.0PheTrp: 0.0 ± 0.0
0.657PheTyr: 0.657 ± 0.172
0.0PheXaa: 0.0 ± 0.0
Gly
3.614GlyAla: 3.614 ± 1.209
2.3GlyCys: 2.3 ± 0.721
4.599GlyAsp: 4.599 ± 0.145
4.271GlyGlu: 4.271 ± 1.91
2.3GlyPhe: 2.3 ± 0.192
1.643GlyGly: 1.643 ± 1.223
0.986GlyHis: 0.986 ± 0.007
5.256GlyIle: 5.256 ± 0.317
4.928GlyLys: 4.928 ± 0.495
3.614GlyLeu: 3.614 ± 0.377
1.643GlyMet: 1.643 ± 0.893
1.314GlyAsn: 1.314 ± 0.344
1.643GlyPro: 1.643 ± 0.165
0.986GlyGln: 0.986 ± 0.007
3.285GlyArg: 3.285 ± 0.199
5.585GlySer: 5.585 ± 1.196
2.957GlyThr: 2.957 ± 0.02
5.256GlyVal: 5.256 ± 1.375
0.329GlyTrp: 0.329 ± 0.179
2.628GlyTyr: 2.628 ± 0.687
0.0GlyXaa: 0.0 ± 0.0
His
2.3HisAla: 2.3 ± 0.721
0.329HisCys: 0.329 ± 0.179
0.329HisAsp: 0.329 ± 0.179
0.329HisGlu: 0.329 ± 0.179
1.314HisPhe: 1.314 ± 0.185
2.3HisGly: 2.3 ± 0.192
0.657HisHis: 0.657 ± 0.357
1.314HisIle: 1.314 ± 0.714
0.657HisLys: 0.657 ± 0.172
1.971HisLeu: 1.971 ± 0.515
0.657HisMet: 0.657 ± 0.357
0.986HisAsn: 0.986 ± 0.007
1.314HisPro: 1.314 ± 0.185
1.643HisGln: 1.643 ± 0.364
0.986HisArg: 0.986 ± 0.007
1.314HisSer: 1.314 ± 0.714
1.643HisThr: 1.643 ± 0.165
1.971HisVal: 1.971 ± 1.071
0.329HisTrp: 0.329 ± 0.179
0.657HisTyr: 0.657 ± 0.357
0.0HisXaa: 0.0 ± 0.0
Ile
5.585IleAla: 5.585 ± 0.39
0.986IleCys: 0.986 ± 0.536
4.928IleAsp: 4.928 ± 1.024
1.314IleGlu: 1.314 ± 0.714
2.628IlePhe: 2.628 ± 0.899
2.957IleGly: 2.957 ± 1.038
0.657IleHis: 0.657 ± 0.357
2.3IleIle: 2.3 ± 0.866
1.643IleLys: 1.643 ± 0.165
4.928IleLeu: 4.928 ± 1.091
0.986IleMet: 0.986 ± 0.536
1.314IleAsn: 1.314 ± 0.185
3.942IlePro: 3.942 ± 0.502
1.314IleGln: 1.314 ± 0.185
4.271IleArg: 4.271 ± 1.263
5.256IleSer: 5.256 ± 1.375
4.928IleThr: 4.928 ± 1.553
3.614IleVal: 3.614 ± 0.681
0.329IleTrp: 0.329 ± 0.35
1.643IleTyr: 1.643 ± 0.165
0.0IleXaa: 0.0 ± 0.0
Lys
4.599LysAla: 4.599 ± 0.384
0.986LysCys: 0.986 ± 0.536
2.957LysAsp: 2.957 ± 1.078
1.643LysGlu: 1.643 ± 0.364
0.986LysPhe: 0.986 ± 0.522
3.285LysGly: 3.285 ± 0.199
0.329LysHis: 0.329 ± 0.179
1.643LysIle: 1.643 ± 0.165
1.314LysLys: 1.314 ± 0.185
6.242LysLeu: 6.242 ± 0.747
0.657LysMet: 0.657 ± 0.172
0.986LysAsn: 0.986 ± 0.536
1.643LysPro: 1.643 ± 0.165
1.643LysGln: 1.643 ± 0.165
0.986LysArg: 0.986 ± 0.536
2.628LysSer: 2.628 ± 0.158
4.271LysThr: 4.271 ± 1.263
2.957LysVal: 2.957 ± 0.549
0.329LysTrp: 0.329 ± 0.35
1.314LysTyr: 1.314 ± 0.714
0.0LysXaa: 0.0 ± 0.0
Leu
4.928LeuAla: 4.928 ± 1.091
2.628LeuCys: 2.628 ± 0.158
3.942LeuAsp: 3.942 ± 0.556
4.599LeuGlu: 4.599 ± 0.145
2.957LeuPhe: 2.957 ± 0.02
3.942LeuGly: 3.942 ± 1.084
2.957LeuHis: 2.957 ± 1.607
2.628LeuIle: 2.628 ± 0.37
4.271LeuLys: 4.271 ± 1.792
9.855LeuLeu: 9.855 ± 2.711
1.314LeuMet: 1.314 ± 0.714
3.285LeuAsn: 3.285 ± 0.859
5.585LeuPro: 5.585 ± 0.667
3.614LeuGln: 3.614 ± 0.152
5.913LeuArg: 5.913 ± 0.04
10.512LeuSer: 10.512 ± 0.105
4.599LeuThr: 4.599 ± 0.384
9.527LeuVal: 9.527 ± 1.169
0.986LeuTrp: 0.986 ± 0.522
3.942LeuTyr: 3.942 ± 0.027
0.0LeuXaa: 0.0 ± 0.0
Met
0.657MetAla: 0.657 ± 0.172
0.329MetCys: 0.329 ± 0.179
1.314MetAsp: 1.314 ± 0.185
1.971MetGlu: 1.971 ± 1.071
0.986MetPhe: 0.986 ± 0.536
0.986MetGly: 0.986 ± 0.522
0.0MetHis: 0.0 ± 0.0
1.971MetIle: 1.971 ± 0.013
0.657MetLys: 0.657 ± 0.357
2.3MetLeu: 2.3 ± 0.721
0.0MetMet: 0.0 ± 0.0
0.986MetAsn: 0.986 ± 0.522
0.657MetPro: 0.657 ± 0.357
0.329MetGln: 0.329 ± 0.179
0.0MetArg: 0.0 ± 0.0
1.643MetSer: 1.643 ± 0.165
0.0MetThr: 0.0 ± 0.0
1.643MetVal: 1.643 ± 0.364
0.657MetTrp: 0.657 ± 0.357
0.986MetTyr: 0.986 ± 0.007
0.0MetXaa: 0.0 ± 0.0
Asn
1.971AsnAla: 1.971 ± 1.044
0.657AsnCys: 0.657 ± 0.357
2.3AsnAsp: 2.3 ± 1.395
1.971AsnGlu: 1.971 ± 0.013
0.986AsnPhe: 0.986 ± 0.007
2.3AsnGly: 2.3 ± 0.337
0.657AsnHis: 0.657 ± 0.357
1.971AsnIle: 1.971 ± 1.044
1.643AsnLys: 1.643 ± 1.223
4.928AsnLeu: 4.928 ± 1.553
1.314AsnMet: 1.314 ± 0.185
0.986AsnAsn: 0.986 ± 0.522
2.957AsnPro: 2.957 ± 0.549
1.971AsnGln: 1.971 ± 0.542
1.643AsnArg: 1.643 ± 0.893
3.942AsnSer: 3.942 ± 0.027
1.314AsnThr: 1.314 ± 0.185
4.271AsnVal: 4.271 ± 0.324
0.0AsnTrp: 0.0 ± 0.0
0.329AsnTyr: 0.329 ± 0.179
0.0AsnXaa: 0.0 ± 0.0
Pro
3.614ProAla: 3.614 ± 1.209
0.657ProCys: 0.657 ± 0.357
2.957ProAsp: 2.957 ± 0.02
1.643ProGlu: 1.643 ± 0.165
3.614ProPhe: 3.614 ± 0.681
4.928ProGly: 4.928 ± 1.024
1.643ProHis: 1.643 ± 0.364
3.285ProIle: 3.285 ± 0.199
1.971ProLys: 1.971 ± 0.013
5.585ProLeu: 5.585 ± 0.39
0.986ProMet: 0.986 ± 0.536
2.3ProAsn: 2.3 ± 0.337
4.271ProPro: 4.271 ± 0.205
1.971ProGln: 1.971 ± 0.013
3.614ProArg: 3.614 ± 0.377
5.585ProSer: 5.585 ± 0.919
1.971ProThr: 1.971 ± 0.515
3.614ProVal: 3.614 ± 1.209
0.329ProTrp: 0.329 ± 0.35
1.971ProTyr: 1.971 ± 0.515
0.0ProXaa: 0.0 ± 0.0
Gln
1.971GlnAla: 1.971 ± 0.013
1.643GlnCys: 1.643 ± 0.893
1.643GlnAsp: 1.643 ± 0.165
1.971GlnGlu: 1.971 ± 1.071
1.643GlnPhe: 1.643 ± 0.165
2.628GlnGly: 2.628 ± 1.216
0.657GlnHis: 0.657 ± 0.357
2.3GlnIle: 2.3 ± 0.337
1.643GlnLys: 1.643 ± 0.893
3.614GlnLeu: 3.614 ± 0.377
1.314GlnMet: 1.314 ± 0.344
1.643GlnAsn: 1.643 ± 0.694
2.3GlnPro: 2.3 ± 0.192
1.314GlnGln: 1.314 ± 0.185
1.643GlnArg: 1.643 ± 0.893
3.285GlnSer: 3.285 ± 0.33
2.3GlnThr: 2.3 ± 1.395
1.971GlnVal: 1.971 ± 1.044
0.0GlnTrp: 0.0 ± 0.0
0.986GlnTyr: 0.986 ± 0.007
0.0GlnXaa: 0.0 ± 0.0
Arg
3.942ArgAla: 3.942 ± 1.084
1.314ArgCys: 1.314 ± 0.185
3.285ArgAsp: 3.285 ± 1.256
2.3ArgGlu: 2.3 ± 0.721
1.314ArgPhe: 1.314 ± 0.872
3.285ArgGly: 3.285 ± 0.859
1.314ArgHis: 1.314 ± 0.714
2.957ArgIle: 2.957 ± 0.549
2.3ArgLys: 2.3 ± 1.25
5.585ArgLeu: 5.585 ± 0.138
0.657ArgMet: 0.657 ± 0.357
1.971ArgAsn: 1.971 ± 0.013
1.643ArgPro: 1.643 ± 0.364
1.314ArgGln: 1.314 ± 0.185
3.285ArgArg: 3.285 ± 0.727
5.256ArgSer: 5.256 ± 0.741
3.942ArgThr: 3.942 ± 0.556
4.928ArgVal: 4.928 ± 0.562
0.0ArgTrp: 0.0 ± 0.0
1.643ArgTyr: 1.643 ± 0.364
0.0ArgXaa: 0.0 ± 0.0
Ser
5.585SerAla: 5.585 ± 0.919
0.657SerCys: 0.657 ± 0.357
3.942SerAsp: 3.942 ± 2.089
4.271SerGlu: 4.271 ± 0.852
6.57SerPhe: 6.57 ± 0.132
5.585SerGly: 5.585 ± 1.196
2.3SerHis: 2.3 ± 0.192
4.599SerIle: 4.599 ± 1.732
4.271SerLys: 4.271 ± 1.792
8.541SerLeu: 8.541 ± 1.468
1.643SerMet: 1.643 ± 0.533
3.942SerAsn: 3.942 ± 0.027
6.242SerPro: 6.242 ± 0.747
2.628SerGln: 2.628 ± 0.158
6.242SerArg: 6.242 ± 1.276
10.512SerSer: 10.512 ± 0.953
2.957SerThr: 2.957 ± 0.509
6.57SerVal: 6.57 ± 2.776
1.643SerTrp: 1.643 ± 0.165
4.599SerTyr: 4.599 ± 1.203
0.0SerXaa: 0.0 ± 0.0
Thr
3.285ThrAla: 3.285 ± 1.256
0.657ThrCys: 0.657 ± 0.357
4.271ThrAsp: 4.271 ± 0.852
3.614ThrGlu: 3.614 ± 0.152
2.957ThrPhe: 2.957 ± 0.509
1.314ThrGly: 1.314 ± 0.185
2.628ThrHis: 2.628 ± 0.687
2.3ThrIle: 2.3 ± 0.866
1.643ThrLys: 1.643 ± 0.165
6.242ThrLeu: 6.242 ± 1.368
0.986ThrMet: 0.986 ± 0.007
1.643ThrAsn: 1.643 ± 0.364
1.971ThrPro: 1.971 ± 0.013
4.599ThrGln: 4.599 ± 0.674
4.271ThrArg: 4.271 ± 1.263
3.942ThrSer: 3.942 ± 1.56
3.942ThrThr: 3.942 ± 1.031
5.913ThrVal: 5.913 ± 1.018
0.657ThrTrp: 0.657 ± 0.357
1.971ThrTyr: 1.971 ± 0.542
0.0ThrXaa: 0.0 ± 0.0
Val
5.256ValAla: 5.256 ± 1.903
2.957ValCys: 2.957 ± 1.078
5.256ValAsp: 5.256 ± 0.212
6.57ValGlu: 6.57 ± 0.132
3.285ValPhe: 3.285 ± 0.33
4.271ValGly: 4.271 ± 1.381
2.3ValHis: 2.3 ± 0.337
4.599ValIle: 4.599 ± 1.203
3.285ValLys: 3.285 ± 0.199
4.599ValLeu: 4.599 ± 1.203
0.657ValMet: 0.657 ± 0.463
4.271ValAsn: 4.271 ± 0.852
2.957ValPro: 2.957 ± 0.549
5.256ValGln: 5.256 ± 0.212
3.285ValArg: 3.285 ± 0.33
7.227ValSer: 7.227 ± 2.419
6.242ValThr: 6.242 ± 1.897
7.556ValVal: 7.556 ± 2.769
0.329ValTrp: 0.329 ± 0.179
2.628ValTyr: 2.628 ± 0.37
0.0ValXaa: 0.0 ± 0.0
Trp
0.329TrpAla: 0.329 ± 0.179
0.0TrpCys: 0.0 ± 0.0
0.657TrpAsp: 0.657 ± 0.357
0.329TrpGlu: 0.329 ± 0.179
0.0TrpPhe: 0.0 ± 0.0
0.329TrpGly: 0.329 ± 0.179
0.0TrpHis: 0.0 ± 0.0
0.329TrpIle: 0.329 ± 0.179
0.0TrpLys: 0.0 ± 0.0
2.3TrpLeu: 2.3 ± 0.337
0.0TrpMet: 0.0 ± 0.0
0.657TrpAsn: 0.657 ± 0.172
0.329TrpPro: 0.329 ± 0.35
0.0TrpGln: 0.0 ± 0.0
0.329TrpArg: 0.329 ± 0.35
0.657TrpSer: 0.657 ± 0.357
0.986TrpThr: 0.986 ± 0.007
0.657TrpVal: 0.657 ± 0.701
0.657TrpTrp: 0.657 ± 0.701
0.657TrpTyr: 0.657 ± 0.357
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.986TyrAla: 0.986 ± 0.007
0.657TyrCys: 0.657 ± 0.172
1.971TyrAsp: 1.971 ± 0.542
1.643TyrGlu: 1.643 ± 1.223
1.971TyrPhe: 1.971 ± 0.013
2.3TyrGly: 2.3 ± 0.866
0.329TyrHis: 0.329 ± 0.179
1.643TyrIle: 1.643 ± 0.893
0.986TyrLys: 0.986 ± 0.007
2.628TyrLeu: 2.628 ± 0.899
0.329TyrMet: 0.329 ± 0.179
1.643TyrAsn: 1.643 ± 0.893
3.614TyrPro: 3.614 ± 0.152
0.329TyrGln: 0.329 ± 0.179
1.314TyrArg: 1.314 ± 0.344
3.942TyrSer: 3.942 ± 0.502
3.942TyrThr: 3.942 ± 0.502
1.971TyrVal: 1.971 ± 0.013
0.329TyrTrp: 0.329 ± 0.179
0.986TyrTyr: 0.986 ± 0.536
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3045 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski