Amino acid dipepetide frequency for Raspberry leaf blotch emaravirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.426AlaAla: 0.426 ± 0.412
0.853AlaCys: 0.853 ± 0.472
0.853AlaAsp: 0.853 ± 0.476
3.197AlaGlu: 3.197 ± 1.181
2.131AlaPhe: 2.131 ± 0.675
0.639AlaGly: 0.639 ± 0.599
0.639AlaHis: 0.639 ± 0.266
4.263AlaIle: 4.263 ± 0.581
3.41AlaLys: 3.41 ± 0.806
2.344AlaLeu: 2.344 ± 0.609
0.853AlaMet: 0.853 ± 0.547
2.131AlaAsn: 2.131 ± 0.904
0.639AlaPro: 0.639 ± 0.295
0.426AlaGln: 0.426 ± 0.356
1.279AlaArg: 1.279 ± 0.292
2.131AlaSer: 2.131 ± 1.073
2.131AlaThr: 2.131 ± 0.627
3.41AlaVal: 3.41 ± 1.379
0.213AlaTrp: 0.213 ± 0.244
2.131AlaTyr: 2.131 ± 0.666
0.0AlaXaa: 0.0 ± 0.0
Cys
0.213CysAla: 0.213 ± 0.36
0.426CysCys: 0.426 ± 0.396
0.639CysAsp: 0.639 ± 0.248
0.853CysGlu: 0.853 ± 0.725
0.853CysPhe: 0.853 ± 0.244
1.066CysGly: 1.066 ± 0.339
0.213CysHis: 0.213 ± 0.235
2.131CysIle: 2.131 ± 0.934
1.279CysLys: 1.279 ± 0.409
1.066CysLeu: 1.066 ± 0.461
0.426CysMet: 0.426 ± 0.209
0.853CysAsn: 0.853 ± 0.472
0.426CysPro: 0.426 ± 0.272
0.426CysGln: 0.426 ± 0.414
0.426CysArg: 0.426 ± 0.209
1.705CysSer: 1.705 ± 0.705
1.918CysThr: 1.918 ± 1.056
1.066CysVal: 1.066 ± 0.445
0.426CysTrp: 0.426 ± 0.501
1.705CysTyr: 1.705 ± 0.601
0.0CysXaa: 0.0 ± 0.0
Asp
2.131AspAla: 2.131 ± 0.567
1.492AspCys: 1.492 ± 1.01
5.328AspAsp: 5.328 ± 1.178
5.328AspGlu: 5.328 ± 0.7
4.263AspPhe: 4.263 ± 0.691
2.771AspGly: 2.771 ± 1.152
1.279AspHis: 1.279 ± 0.385
5.968AspIle: 5.968 ± 1.123
3.197AspLys: 3.197 ± 0.949
8.312AspLeu: 8.312 ± 1.519
2.984AspMet: 2.984 ± 0.7
4.476AspAsn: 4.476 ± 1.499
1.279AspPro: 1.279 ± 0.562
1.066AspGln: 1.066 ± 0.391
2.984AspArg: 2.984 ± 0.614
5.328AspSer: 5.328 ± 1.363
2.558AspThr: 2.558 ± 0.555
4.689AspVal: 4.689 ± 0.956
0.213AspTrp: 0.213 ± 0.318
4.902AspTyr: 4.902 ± 1.28
0.0AspXaa: 0.0 ± 0.0
Glu
2.771GluAla: 2.771 ± 0.523
1.279GluCys: 1.279 ± 0.45
5.328GluAsp: 5.328 ± 1.097
2.344GluGlu: 2.344 ± 0.788
3.623GluPhe: 3.623 ± 0.769
0.853GluGly: 0.853 ± 0.454
0.853GluHis: 0.853 ± 0.418
6.82GluIle: 6.82 ± 1.367
5.754GluLys: 5.754 ± 0.998
5.541GluLeu: 5.541 ± 1.533
1.918GluMet: 1.918 ± 0.59
5.541GluAsn: 5.541 ± 1.332
1.066GluPro: 1.066 ± 0.366
0.853GluGln: 0.853 ± 0.393
2.771GluArg: 2.771 ± 1.276
6.181GluSer: 6.181 ± 1.036
2.131GluThr: 2.131 ± 0.474
3.197GluVal: 3.197 ± 0.761
0.213GluTrp: 0.213 ± 0.136
3.41GluTyr: 3.41 ± 1.311
0.0GluXaa: 0.0 ± 0.0
Phe
1.279PheAla: 1.279 ± 0.409
0.213PheCys: 0.213 ± 0.136
3.836PheAsp: 3.836 ± 1.083
2.558PheGlu: 2.558 ± 0.763
1.492PhePhe: 1.492 ± 0.478
2.131PheGly: 2.131 ± 0.612
1.279PheHis: 1.279 ± 0.627
3.836PheIle: 3.836 ± 1.049
3.197PheLys: 3.197 ± 0.868
3.41PheLeu: 3.41 ± 0.853
1.279PheMet: 1.279 ± 0.494
3.836PheAsn: 3.836 ± 1.564
1.918PhePro: 1.918 ± 0.856
1.492PheGln: 1.492 ± 0.49
1.705PheArg: 1.705 ± 0.623
4.476PheSer: 4.476 ± 1.089
1.918PheThr: 1.918 ± 0.368
1.492PheVal: 1.492 ± 0.502
0.0PheTrp: 0.0 ± 0.0
4.476PheTyr: 4.476 ± 0.9
0.0PheXaa: 0.0 ± 0.0
Gly
1.066GlyAla: 1.066 ± 0.44
0.639GlyCys: 0.639 ± 0.266
1.705GlyAsp: 1.705 ± 0.466
3.197GlyGlu: 3.197 ± 1.168
1.705GlyPhe: 1.705 ± 0.496
0.853GlyGly: 0.853 ± 0.406
0.639GlyHis: 0.639 ± 0.356
2.771GlyIle: 2.771 ± 1.236
3.836GlyLys: 3.836 ± 1.381
2.984GlyLeu: 2.984 ± 0.847
0.426GlyMet: 0.426 ± 0.395
1.492GlyAsn: 1.492 ± 0.74
0.213GlyPro: 0.213 ± 0.136
0.639GlyGln: 0.639 ± 0.343
0.0GlyArg: 0.0 ± 0.0
1.279GlySer: 1.279 ± 0.562
1.066GlyThr: 1.066 ± 0.3
1.705GlyVal: 1.705 ± 0.925
0.213GlyTrp: 0.213 ± 0.244
1.705GlyTyr: 1.705 ± 0.494
0.0GlyXaa: 0.0 ± 0.0
His
0.639HisAla: 0.639 ± 0.295
0.426HisCys: 0.426 ± 0.209
1.705HisAsp: 1.705 ± 0.595
0.853HisGlu: 0.853 ± 0.465
0.639HisPhe: 0.639 ± 0.619
0.426HisGly: 0.426 ± 0.211
0.213HisHis: 0.213 ± 0.136
1.918HisIle: 1.918 ± 0.57
1.492HisLys: 1.492 ± 0.404
1.918HisLeu: 1.918 ± 0.498
0.426HisMet: 0.426 ± 0.272
1.918HisAsn: 1.918 ± 0.631
0.426HisPro: 0.426 ± 0.272
0.426HisGln: 0.426 ± 0.22
0.853HisArg: 0.853 ± 0.393
1.918HisSer: 1.918 ± 0.521
0.0HisThr: 0.0 ± 0.0
1.066HisVal: 1.066 ± 0.427
0.0HisTrp: 0.0 ± 0.0
1.492HisTyr: 1.492 ± 0.387
0.0HisXaa: 0.0 ± 0.0
Ile
2.771IleAla: 2.771 ± 0.662
1.918IleCys: 1.918 ± 0.858
6.394IleAsp: 6.394 ± 1.453
4.476IleGlu: 4.476 ± 1.06
3.623IlePhe: 3.623 ± 0.827
2.344IleGly: 2.344 ± 0.794
0.639IleHis: 0.639 ± 0.375
7.033IleIle: 7.033 ± 1.291
9.804IleLys: 9.804 ± 0.632
8.951IleLeu: 8.951 ± 2.179
2.771IleMet: 2.771 ± 0.507
10.017IleAsn: 10.017 ± 2.634
1.918IlePro: 1.918 ± 1.002
1.705IleGln: 1.705 ± 0.403
2.771IleArg: 2.771 ± 0.474
8.951IleSer: 8.951 ± 2.006
4.902IleThr: 4.902 ± 0.947
5.968IleVal: 5.968 ± 1.142
0.213IleTrp: 0.213 ± 0.25
4.902IleTyr: 4.902 ± 1.027
0.0IleXaa: 0.0 ± 0.0
Lys
2.344LysAla: 2.344 ± 0.941
1.492LysCys: 1.492 ± 0.832
5.968LysAsp: 5.968 ± 0.878
4.476LysGlu: 4.476 ± 0.524
4.476LysPhe: 4.476 ± 1.061
2.771LysGly: 2.771 ± 0.878
1.918LysHis: 1.918 ± 0.531
9.378LysIle: 9.378 ± 2.024
10.017LysLys: 10.017 ± 1.447
10.017LysLeu: 10.017 ± 1.928
4.049LysMet: 4.049 ± 1.398
6.394LysAsn: 6.394 ± 0.873
1.705LysPro: 1.705 ± 0.327
1.279LysGln: 1.279 ± 0.609
2.344LysArg: 2.344 ± 0.601
7.46LysSer: 7.46 ± 1.086
4.689LysThr: 4.689 ± 0.377
5.328LysVal: 5.328 ± 1.313
0.426LysTrp: 0.426 ± 0.272
5.115LysTyr: 5.115 ± 1.149
0.0LysXaa: 0.0 ± 0.0
Leu
3.623LeuAla: 3.623 ± 1.605
1.705LeuCys: 1.705 ± 0.564
5.968LeuAsp: 5.968 ± 1.296
5.754LeuGlu: 5.754 ± 1.842
4.689LeuPhe: 4.689 ± 0.668
2.344LeuGly: 2.344 ± 0.847
1.492LeuHis: 1.492 ± 0.741
7.46LeuIle: 7.46 ± 1.884
7.673LeuLys: 7.673 ± 1.698
6.394LeuLeu: 6.394 ± 1.104
1.492LeuMet: 1.492 ± 0.418
8.099LeuAsn: 8.099 ± 0.577
4.263LeuPro: 4.263 ± 1.252
2.558LeuGln: 2.558 ± 1.106
4.476LeuArg: 4.476 ± 0.823
10.443LeuSer: 10.443 ± 2.261
4.902LeuThr: 4.902 ± 0.899
4.263LeuVal: 4.263 ± 1.081
0.853LeuTrp: 0.853 ± 1.067
5.968LeuTyr: 5.968 ± 1.066
0.0LeuXaa: 0.0 ± 0.0
Met
2.558MetAla: 2.558 ± 1.134
0.426MetCys: 0.426 ± 0.22
1.705MetAsp: 1.705 ± 0.426
2.558MetGlu: 2.558 ± 0.913
0.639MetPhe: 0.639 ± 0.43
0.853MetGly: 0.853 ± 0.333
0.213MetHis: 0.213 ± 0.235
2.558MetIle: 2.558 ± 0.767
1.705MetLys: 1.705 ± 1.164
2.558MetLeu: 2.558 ± 0.355
1.066MetMet: 1.066 ± 0.452
2.344MetAsn: 2.344 ± 0.715
0.213MetPro: 0.213 ± 0.235
0.426MetGln: 0.426 ± 0.272
0.426MetArg: 0.426 ± 0.338
2.558MetSer: 2.558 ± 0.482
1.705MetThr: 1.705 ± 0.748
1.279MetVal: 1.279 ± 0.385
0.213MetTrp: 0.213 ± 0.136
0.853MetTyr: 0.853 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
3.836AsnAla: 3.836 ± 0.597
1.279AsnCys: 1.279 ± 0.4
5.115AsnAsp: 5.115 ± 0.513
5.328AsnGlu: 5.328 ± 1.137
3.41AsnPhe: 3.41 ± 0.811
2.984AsnGly: 2.984 ± 0.73
2.771AsnHis: 2.771 ± 1.008
6.181AsnIle: 6.181 ± 0.612
8.951AsnLys: 8.951 ± 2.075
10.87AsnLeu: 10.87 ± 1.04
2.131AsnMet: 2.131 ± 0.674
7.886AsnAsn: 7.886 ± 0.933
2.771AsnPro: 2.771 ± 0.829
1.705AsnGln: 1.705 ± 0.781
2.131AsnArg: 2.131 ± 0.671
4.476AsnSer: 4.476 ± 1.086
4.263AsnThr: 4.263 ± 0.713
2.558AsnVal: 2.558 ± 0.576
0.213AsnTrp: 0.213 ± 0.136
5.115AsnTyr: 5.115 ± 1.802
0.0AsnXaa: 0.0 ± 0.0
Pro
0.213ProAla: 0.213 ± 0.244
0.213ProCys: 0.213 ± 0.235
1.918ProAsp: 1.918 ± 0.548
2.344ProGlu: 2.344 ± 0.774
1.066ProPhe: 1.066 ± 0.3
0.639ProGly: 0.639 ± 0.575
0.426ProHis: 0.426 ± 0.272
2.984ProIle: 2.984 ± 0.825
1.705ProLys: 1.705 ± 0.5
2.558ProLeu: 2.558 ± 1.099
0.426ProMet: 0.426 ± 0.211
1.279ProAsn: 1.279 ± 0.469
0.426ProPro: 0.426 ± 0.211
1.066ProGln: 1.066 ± 0.484
1.279ProArg: 1.279 ± 0.434
1.279ProSer: 1.279 ± 0.385
1.066ProThr: 1.066 ± 0.487
1.066ProVal: 1.066 ± 0.321
0.0ProTrp: 0.0 ± 0.0
1.705ProTyr: 1.705 ± 0.583
0.0ProXaa: 0.0 ± 0.0
Gln
1.066GlnAla: 1.066 ± 0.452
0.0GlnCys: 0.0 ± 0.0
1.492GlnAsp: 1.492 ± 0.446
1.279GlnGlu: 1.279 ± 0.486
1.492GlnPhe: 1.492 ± 0.419
0.426GlnGly: 0.426 ± 0.22
0.0GlnHis: 0.0 ± 0.0
1.705GlnIle: 1.705 ± 1.026
1.918GlnLys: 1.918 ± 0.653
2.344GlnLeu: 2.344 ± 1.008
0.426GlnMet: 0.426 ± 0.211
2.131GlnAsn: 2.131 ± 0.735
0.426GlnPro: 0.426 ± 0.22
0.639GlnGln: 0.639 ± 0.266
1.918GlnArg: 1.918 ± 1.002
0.639GlnSer: 0.639 ± 0.273
0.853GlnThr: 0.853 ± 0.414
1.918GlnVal: 1.918 ± 0.532
0.213GlnTrp: 0.213 ± 0.136
0.639GlnTyr: 0.639 ± 0.273
0.0GlnXaa: 0.0 ± 0.0
Arg
0.639ArgAla: 0.639 ± 0.408
0.853ArgCys: 0.853 ± 0.322
3.197ArgAsp: 3.197 ± 1.05
1.705ArgGlu: 1.705 ± 0.446
2.344ArgPhe: 2.344 ± 0.722
0.426ArgGly: 0.426 ± 0.209
1.066ArgHis: 1.066 ± 0.607
3.41ArgIle: 3.41 ± 1.434
2.558ArgLys: 2.558 ± 0.904
4.263ArgLeu: 4.263 ± 0.659
0.639ArgMet: 0.639 ± 0.503
3.197ArgAsn: 3.197 ± 0.772
0.639ArgPro: 0.639 ± 0.248
0.853ArgGln: 0.853 ± 0.544
1.918ArgArg: 1.918 ± 0.554
3.41ArgSer: 3.41 ± 1.148
1.492ArgThr: 1.492 ± 0.332
2.131ArgVal: 2.131 ± 0.619
0.0ArgTrp: 0.0 ± 0.0
1.705ArgTyr: 1.705 ± 0.657
0.0ArgXaa: 0.0 ± 0.0
Ser
2.344SerAla: 2.344 ± 0.785
1.918SerCys: 1.918 ± 0.682
5.115SerAsp: 5.115 ± 0.762
7.246SerGlu: 7.246 ± 1.151
2.771SerPhe: 2.771 ± 0.622
3.197SerGly: 3.197 ± 0.784
1.918SerHis: 1.918 ± 0.893
7.886SerIle: 7.886 ± 1.478
7.46SerLys: 7.46 ± 1.261
7.46SerLeu: 7.46 ± 1.956
1.279SerMet: 1.279 ± 0.434
7.246SerAsn: 7.246 ± 2.128
0.853SerPro: 0.853 ± 0.388
1.492SerGln: 1.492 ± 0.575
1.705SerArg: 1.705 ± 0.716
5.968SerSer: 5.968 ± 0.872
5.328SerThr: 5.328 ± 0.761
4.263SerVal: 4.263 ± 1.431
0.639SerTrp: 0.639 ± 0.492
5.541SerTyr: 5.541 ± 1.05
0.0SerXaa: 0.0 ± 0.0
Thr
1.066ThrAla: 1.066 ± 0.292
1.279ThrCys: 1.279 ± 0.54
2.558ThrAsp: 2.558 ± 0.647
2.984ThrGlu: 2.984 ± 0.841
2.344ThrPhe: 2.344 ± 0.557
1.492ThrGly: 1.492 ± 0.602
0.853ThrHis: 0.853 ± 0.62
4.902ThrIle: 4.902 ± 1.347
4.476ThrLys: 4.476 ± 1.153
5.328ThrLeu: 5.328 ± 0.696
1.066ThrMet: 1.066 ± 0.679
2.771ThrAsn: 2.771 ± 0.671
1.492ThrPro: 1.492 ± 0.502
1.492ThrGln: 1.492 ± 0.606
2.558ThrArg: 2.558 ± 0.586
3.623ThrSer: 3.623 ± 0.627
2.558ThrThr: 2.558 ± 0.82
3.623ThrVal: 3.623 ± 1.481
0.213ThrTrp: 0.213 ± 0.136
2.771ThrTyr: 2.771 ± 0.719
0.0ThrXaa: 0.0 ± 0.0
Val
2.771ValAla: 2.771 ± 0.636
0.426ValCys: 0.426 ± 0.209
6.607ValAsp: 6.607 ± 1.174
2.771ValGlu: 2.771 ± 0.57
1.705ValPhe: 1.705 ± 0.679
0.853ValGly: 0.853 ± 0.624
0.639ValHis: 0.639 ± 0.266
4.689ValIle: 4.689 ± 1.013
4.902ValLys: 4.902 ± 1.078
3.197ValLeu: 3.197 ± 1.154
1.918ValMet: 1.918 ± 0.667
4.476ValAsn: 4.476 ± 0.884
2.131ValPro: 2.131 ± 0.917
1.918ValGln: 1.918 ± 0.578
2.558ValArg: 2.558 ± 0.702
4.476ValSer: 4.476 ± 2.242
1.918ValThr: 1.918 ± 0.539
3.197ValVal: 3.197 ± 0.348
0.426ValTrp: 0.426 ± 0.577
2.984ValTyr: 2.984 ± 0.565
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.213TrpCys: 0.213 ± 0.25
0.426TrpAsp: 0.426 ± 0.506
0.639TrpGlu: 0.639 ± 0.35
0.639TrpPhe: 0.639 ± 0.467
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.426TrpIle: 0.426 ± 0.44
0.426TrpLys: 0.426 ± 0.495
0.213TrpLeu: 0.213 ± 0.136
0.0TrpMet: 0.0 ± 0.0
0.639TrpAsn: 0.639 ± 0.443
0.213TrpPro: 0.213 ± 0.136
0.213TrpGln: 0.213 ± 0.136
0.213TrpArg: 0.213 ± 0.321
0.853TrpSer: 0.853 ± 0.393
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.213TrpTyr: 0.213 ± 0.395
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.344TyrAla: 2.344 ± 1.0
1.066TyrCys: 1.066 ± 0.484
4.689TyrAsp: 4.689 ± 0.867
2.771TyrGlu: 2.771 ± 0.713
1.918TyrPhe: 1.918 ± 0.749
1.066TyrGly: 1.066 ± 0.68
1.705TyrHis: 1.705 ± 0.499
5.754TyrIle: 5.754 ± 1.121
7.886TyrLys: 7.886 ± 1.16
4.689TyrLeu: 4.689 ± 0.921
1.066TyrMet: 1.066 ± 0.392
7.246TyrAsn: 7.246 ± 1.366
0.639TyrPro: 0.639 ± 0.356
0.853TyrGln: 0.853 ± 0.29
2.131TyrArg: 2.131 ± 0.625
4.476TyrSer: 4.476 ± 0.755
4.049TyrThr: 4.049 ± 1.298
2.344TyrVal: 2.344 ± 0.508
0.639TyrTrp: 0.639 ± 0.443
3.197TyrTyr: 3.197 ± 0.824
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (4693 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski