Amino acid dipepetide frequency for Cucumber mosaic virus (cucumber mosaic cucumovirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.515AlaAla: 6.515 ± 1.211
1.221AlaCys: 1.221 ± 0.497
5.7AlaAsp: 5.7 ± 1.011
6.515AlaGlu: 6.515 ± 1.446
5.293AlaPhe: 5.293 ± 1.501
4.072AlaGly: 4.072 ± 0.888
2.036AlaHis: 2.036 ± 0.651
4.886AlaIle: 4.886 ± 1.074
2.443AlaLys: 2.443 ± 0.727
5.293AlaLeu: 5.293 ± 0.941
3.664AlaMet: 3.664 ± 1.262
2.036AlaAsn: 2.036 ± 0.88
2.85AlaPro: 2.85 ± 0.935
2.036AlaGln: 2.036 ± 0.941
2.85AlaArg: 2.85 ± 2.494
5.7AlaSer: 5.7 ± 2.087
4.072AlaThr: 4.072 ± 0.727
4.479AlaVal: 4.479 ± 1.2
0.814AlaTrp: 0.814 ± 0.255
0.814AlaTyr: 0.814 ± 0.553
0.0AlaXaa: 0.0 ± 0.0
Cys
1.221CysAla: 1.221 ± 0.423
0.407CysCys: 0.407 ± 0.277
2.036CysAsp: 2.036 ± 0.712
2.443CysGlu: 2.443 ± 0.994
1.629CysPhe: 1.629 ± 0.496
1.221CysGly: 1.221 ± 0.83
0.0CysHis: 0.0 ± 0.0
0.814CysIle: 0.814 ± 0.255
0.407CysLys: 0.407 ± 0.277
2.036CysLeu: 2.036 ± 0.651
0.0CysMet: 0.0 ± 0.0
0.814CysAsn: 0.814 ± 0.255
2.85CysPro: 2.85 ± 0.784
0.814CysGln: 0.814 ± 0.255
0.814CysArg: 0.814 ± 0.495
2.85CysSer: 2.85 ± 0.867
0.814CysThr: 0.814 ± 0.553
1.629CysVal: 1.629 ± 0.796
0.0CysTrp: 0.0 ± 0.0
0.814CysTyr: 0.814 ± 0.255
0.0CysXaa: 0.0 ± 0.0
Asp
3.257AspAla: 3.257 ± 0.762
1.221AspCys: 1.221 ± 0.627
4.886AspAsp: 4.886 ± 1.022
2.85AspGlu: 2.85 ± 0.935
2.85AspPhe: 2.85 ± 0.679
4.886AspGly: 4.886 ± 0.711
1.629AspHis: 1.629 ± 0.673
2.036AspIle: 2.036 ± 0.88
4.479AspLys: 4.479 ± 1.142
8.143AspLeu: 8.143 ± 1.838
2.443AspMet: 2.443 ± 0.95
1.221AspAsn: 1.221 ± 0.727
1.629AspPro: 1.629 ± 0.509
1.629AspGln: 1.629 ± 0.509
2.85AspArg: 2.85 ± 1.82
6.107AspSer: 6.107 ± 1.626
3.257AspThr: 3.257 ± 0.749
4.886AspVal: 4.886 ± 1.055
0.814AspTrp: 0.814 ± 0.706
2.443AspTyr: 2.443 ± 0.994
0.0AspXaa: 0.0 ± 0.0
Glu
5.7GluAla: 5.7 ± 1.842
2.443GluCys: 2.443 ± 0.758
3.257GluAsp: 3.257 ± 0.9
3.664GluGlu: 3.664 ± 1.136
3.257GluPhe: 3.257 ± 1.579
2.036GluGly: 2.036 ± 0.824
0.814GluHis: 0.814 ± 0.495
0.814GluIle: 0.814 ± 0.255
3.257GluLys: 3.257 ± 1.018
7.329GluLeu: 7.329 ± 3.342
0.814GluMet: 0.814 ± 0.255
0.814GluAsn: 0.814 ± 0.255
1.629GluPro: 1.629 ± 0.79
2.85GluGln: 2.85 ± 1.006
7.736GluArg: 7.736 ± 1.112
4.886GluSer: 4.886 ± 1.464
3.257GluThr: 3.257 ± 0.507
2.85GluVal: 2.85 ± 0.562
1.221GluTrp: 1.221 ± 0.787
1.221GluTyr: 1.221 ± 0.673
0.0GluXaa: 0.0 ± 0.0
Phe
4.072PheAla: 4.072 ± 0.443
0.814PheCys: 0.814 ± 0.255
4.886PheAsp: 4.886 ± 1.245
3.257PheGlu: 3.257 ± 2.017
1.629PhePhe: 1.629 ± 0.496
2.443PheGly: 2.443 ± 0.764
1.629PheHis: 1.629 ± 1.246
1.221PheIle: 1.221 ± 0.497
2.85PheLys: 2.85 ± 0.562
2.443PheLeu: 2.443 ± 0.994
0.814PheMet: 0.814 ± 0.627
2.443PheAsn: 2.443 ± 0.518
1.629PhePro: 1.629 ± 0.678
2.036PheGln: 2.036 ± 1.29
2.443PheArg: 2.443 ± 0.574
6.107PheSer: 6.107 ± 0.889
2.443PheThr: 2.443 ± 0.692
3.257PheVal: 3.257 ± 0.888
0.407PheTrp: 0.407 ± 0.277
1.629PheTyr: 1.629 ± 0.673
0.0PheXaa: 0.0 ± 0.0
Gly
3.257GlyAla: 3.257 ± 1.219
0.814GlyCys: 0.814 ± 0.255
4.072GlyAsp: 4.072 ± 0.436
2.85GlyGlu: 2.85 ± 0.428
2.036GlyPhe: 2.036 ± 0.726
3.257GlyGly: 3.257 ± 1.075
1.629GlyHis: 1.629 ± 0.673
2.443GlyIle: 2.443 ± 1.211
3.257GlyLys: 3.257 ± 0.993
4.479GlyLeu: 4.479 ± 0.843
1.629GlyMet: 1.629 ± 0.678
2.443GlyAsn: 2.443 ± 0.959
0.814GlyPro: 0.814 ± 0.255
1.221GlyGln: 1.221 ± 0.423
3.257GlyArg: 3.257 ± 1.458
4.072GlySer: 4.072 ± 1.731
4.072GlyThr: 4.072 ± 0.681
5.293GlyVal: 5.293 ± 1.312
0.0GlyTrp: 0.0 ± 0.0
3.257GlyTyr: 3.257 ± 2.138
0.0GlyXaa: 0.0 ± 0.0
His
1.629HisAla: 1.629 ± 0.678
1.221HisCys: 1.221 ± 0.431
2.036HisAsp: 2.036 ± 0.824
0.814HisGlu: 0.814 ± 0.553
1.629HisPhe: 1.629 ± 0.678
2.443HisGly: 2.443 ± 1.255
0.407HisHis: 0.407 ± 0.609
0.814HisIle: 0.814 ± 0.594
2.036HisLys: 2.036 ± 1.312
0.814HisLeu: 0.814 ± 0.255
0.814HisMet: 0.814 ± 0.623
0.814HisAsn: 0.814 ± 0.553
0.814HisPro: 0.814 ± 0.507
1.221HisGln: 1.221 ± 0.424
0.814HisArg: 0.814 ± 0.623
1.221HisSer: 1.221 ± 0.497
0.407HisThr: 0.407 ± 0.277
1.629HisVal: 1.629 ± 0.692
0.407HisTrp: 0.407 ± 0.609
0.814HisTyr: 0.814 ± 0.553
0.0HisXaa: 0.0 ± 0.0
Ile
3.257IleAla: 3.257 ± 0.724
2.036IleCys: 2.036 ± 0.726
3.257IleAsp: 3.257 ± 1.206
2.443IleGlu: 2.443 ± 1.009
0.814IlePhe: 0.814 ± 0.255
2.443IleGly: 2.443 ± 0.967
1.221IleHis: 1.221 ± 0.83
1.629IleIle: 1.629 ± 0.678
3.257IleLys: 3.257 ± 0.803
3.664IleLeu: 3.664 ± 1.062
0.814IleMet: 0.814 ± 0.255
4.072IleAsn: 4.072 ± 0.56
3.257IlePro: 3.257 ± 0.888
0.814IleGln: 0.814 ± 0.495
2.85IleArg: 2.85 ± 1.204
5.293IleSer: 5.293 ± 0.735
3.257IleThr: 3.257 ± 0.888
2.036IleVal: 2.036 ± 0.941
0.814IleTrp: 0.814 ± 0.553
0.814IleTyr: 0.814 ± 0.594
0.0IleXaa: 0.0 ± 0.0
Lys
2.036LysAla: 2.036 ± 0.941
2.036LysCys: 2.036 ± 1.093
1.221LysAsp: 1.221 ± 0.673
2.443LysGlu: 2.443 ± 0.373
2.85LysPhe: 2.85 ± 0.935
1.629LysGly: 1.629 ± 0.796
0.407LysHis: 0.407 ± 0.311
4.886LysIle: 4.886 ± 0.749
4.886LysLys: 4.886 ± 1.534
3.257LysLeu: 3.257 ± 1.363
1.629LysMet: 1.629 ± 0.796
0.814LysAsn: 0.814 ± 0.594
1.629LysPro: 1.629 ± 0.776
2.036LysGln: 2.036 ± 1.288
3.257LysArg: 3.257 ± 0.303
8.55LysSer: 8.55 ± 1.28
3.257LysThr: 3.257 ± 1.51
3.257LysVal: 3.257 ± 1.063
1.629LysTrp: 1.629 ± 0.509
2.85LysTyr: 2.85 ± 0.708
0.0LysXaa: 0.0 ± 0.0
Leu
4.886LeuAla: 4.886 ± 0.799
2.036LeuCys: 2.036 ± 1.15
3.257LeuAsp: 3.257 ± 1.075
3.664LeuGlu: 3.664 ± 1.136
4.072LeuPhe: 4.072 ± 0.838
5.293LeuGly: 5.293 ± 0.909
2.85LeuHis: 2.85 ± 0.762
3.257LeuIle: 3.257 ± 1.018
4.072LeuLys: 4.072 ± 0.56
8.143LeuLeu: 8.143 ± 1.903
1.629LeuMet: 1.629 ± 0.384
5.7LeuAsn: 5.7 ± 0.543
5.7LeuPro: 5.7 ± 1.969
2.443LeuGln: 2.443 ± 0.837
5.7LeuArg: 5.7 ± 1.106
6.922LeuSer: 6.922 ± 1.948
3.664LeuThr: 3.664 ± 1.345
8.55LeuVal: 8.55 ± 1.869
0.407LeuTrp: 0.407 ± 0.311
1.221LeuTyr: 1.221 ± 0.424
0.0LeuXaa: 0.0 ± 0.0
Met
4.072MetAla: 4.072 ± 0.681
0.407MetCys: 0.407 ± 0.277
0.407MetAsp: 0.407 ± 0.462
2.443MetGlu: 2.443 ± 0.959
1.221MetPhe: 1.221 ± 0.673
0.407MetGly: 0.407 ± 0.277
0.0MetHis: 0.0 ± 0.0
1.629MetIle: 1.629 ± 0.79
0.814MetLys: 0.814 ± 0.255
0.814MetLeu: 0.814 ± 0.255
0.814MetMet: 0.814 ± 0.553
1.221MetAsn: 1.221 ± 0.83
0.407MetPro: 0.407 ± 0.311
0.407MetGln: 0.407 ± 0.277
3.664MetArg: 3.664 ± 1.178
2.443MetSer: 2.443 ± 0.373
1.629MetThr: 1.629 ± 0.945
1.629MetVal: 1.629 ± 0.625
0.407MetTrp: 0.407 ± 0.277
0.814MetTyr: 0.814 ± 0.255
0.0MetXaa: 0.0 ± 0.0
Asn
3.257AsnAla: 3.257 ± 1.406
0.407AsnCys: 0.407 ± 0.277
2.036AsnAsp: 2.036 ± 0.651
2.85AsnGlu: 2.85 ± 1.622
1.629AsnPhe: 1.629 ± 0.944
2.443AsnGly: 2.443 ± 0.518
0.814AsnHis: 0.814 ± 0.759
2.036AsnIle: 2.036 ± 0.538
2.443AsnLys: 2.443 ± 1.01
3.664AsnLeu: 3.664 ± 1.07
1.221AsnMet: 1.221 ± 0.431
1.629AsnAsn: 1.629 ± 1.878
0.407AsnPro: 0.407 ± 0.462
0.407AsnGln: 0.407 ± 0.609
2.443AsnArg: 2.443 ± 1.436
3.257AsnSer: 3.257 ± 1.075
1.221AsnThr: 1.221 ± 0.934
2.85AsnVal: 2.85 ± 2.216
0.407AsnTrp: 0.407 ± 0.609
1.221AsnTyr: 1.221 ± 0.727
0.0AsnXaa: 0.0 ± 0.0
Pro
5.293ProAla: 5.293 ± 1.858
1.221ProCys: 1.221 ± 0.497
3.664ProAsp: 3.664 ± 1.127
3.664ProGlu: 3.664 ± 1.068
1.221ProPhe: 1.221 ± 1.045
1.221ProGly: 1.221 ± 0.424
0.407ProHis: 0.407 ± 0.277
2.036ProIle: 2.036 ± 0.712
2.036ProLys: 2.036 ± 1.159
3.664ProLeu: 3.664 ± 0.514
1.221ProMet: 1.221 ± 0.423
0.0ProAsn: 0.0 ± 0.0
3.257ProPro: 3.257 ± 1.206
1.629ProGln: 1.629 ± 1.106
1.221ProArg: 1.221 ± 0.424
2.85ProSer: 2.85 ± 0.852
4.479ProThr: 4.479 ± 1.111
4.072ProVal: 4.072 ± 1.56
0.407ProTrp: 0.407 ± 0.311
0.814ProTyr: 0.814 ± 0.623
0.0ProXaa: 0.0 ± 0.0
Gln
2.85GlnAla: 2.85 ± 1.27
1.221GlnCys: 1.221 ± 0.727
1.629GlnAsp: 1.629 ± 1.106
0.814GlnGlu: 0.814 ± 0.255
2.443GlnPhe: 2.443 ± 0.764
1.629GlnGly: 1.629 ± 0.397
0.407GlnHis: 0.407 ± 0.277
1.221GlnIle: 1.221 ± 0.424
1.221GlnLys: 1.221 ± 0.423
4.072GlnLeu: 4.072 ± 0.789
0.0GlnMet: 0.0 ± 0.0
0.814GlnAsn: 0.814 ± 1.104
1.221GlnPro: 1.221 ± 0.627
1.629GlnGln: 1.629 ± 0.729
3.664GlnArg: 3.664 ± 1.569
2.85GlnSer: 2.85 ± 0.784
2.443GlnThr: 2.443 ± 0.373
2.036GlnVal: 2.036 ± 1.407
0.407GlnTrp: 0.407 ± 0.277
1.221GlnTyr: 1.221 ± 0.701
0.0GlnXaa: 0.0 ± 0.0
Arg
4.479ArgAla: 4.479 ± 0.524
2.443ArgCys: 2.443 ± 0.352
1.629ArgAsp: 1.629 ± 0.509
3.664ArgGlu: 3.664 ± 0.835
2.443ArgPhe: 2.443 ± 0.518
3.664ArgGly: 3.664 ± 1.306
2.443ArgHis: 2.443 ± 1.469
4.072ArgIle: 4.072 ± 0.96
3.257ArgLys: 3.257 ± 1.008
6.515ArgLeu: 6.515 ± 2.055
1.221ArgMet: 1.221 ± 0.616
2.443ArgAsn: 2.443 ± 0.639
4.072ArgPro: 4.072 ± 1.332
1.629ArgGln: 1.629 ± 0.509
5.293ArgArg: 5.293 ± 2.567
4.886ArgSer: 4.886 ± 1.597
4.072ArgThr: 4.072 ± 1.912
4.479ArgVal: 4.479 ± 1.188
0.814ArgTrp: 0.814 ± 0.255
0.814ArgTyr: 0.814 ± 0.553
0.0ArgXaa: 0.0 ± 0.0
Ser
6.107SerAla: 6.107 ± 2.336
0.814SerCys: 0.814 ± 0.623
6.107SerAsp: 6.107 ± 1.849
7.329SerGlu: 7.329 ± 1.87
5.293SerPhe: 5.293 ± 0.909
4.479SerGly: 4.479 ± 1.345
1.221SerHis: 1.221 ± 0.616
4.072SerIle: 4.072 ± 1.109
5.293SerLys: 5.293 ± 0.541
5.293SerLeu: 5.293 ± 0.909
0.407SerMet: 0.407 ± 0.277
3.257SerAsn: 3.257 ± 1.344
4.072SerPro: 4.072 ± 1.756
6.107SerGln: 6.107 ± 0.941
6.515SerArg: 6.515 ± 1.036
9.365SerSer: 9.365 ± 1.632
5.7SerThr: 5.7 ± 1.402
5.7SerVal: 5.7 ± 1.408
0.407SerTrp: 0.407 ± 0.277
4.479SerTyr: 4.479 ± 1.218
0.0SerXaa: 0.0 ± 0.0
Thr
4.479ThrAla: 4.479 ± 1.171
0.0ThrCys: 0.0 ± 0.0
3.664ThrAsp: 3.664 ± 0.521
2.85ThrGlu: 2.85 ± 0.459
4.072ThrPhe: 4.072 ± 1.426
3.257ThrGly: 3.257 ± 0.9
2.443ThrHis: 2.443 ± 0.928
3.257ThrIle: 3.257 ± 0.823
4.072ThrLys: 4.072 ± 0.838
5.293ThrLeu: 5.293 ± 0.631
2.85ThrMet: 2.85 ± 0.89
0.814ThrAsn: 0.814 ± 1.104
2.85ThrPro: 2.85 ± 1.282
1.629ThrGln: 1.629 ± 0.796
3.257ThrArg: 3.257 ± 0.803
4.886ThrSer: 4.886 ± 1.154
3.257ThrThr: 3.257 ± 0.5
4.479ThrVal: 4.479 ± 1.428
0.0ThrTrp: 0.0 ± 0.0
3.257ThrTyr: 3.257 ± 0.5
0.0ThrXaa: 0.0 ± 0.0
Val
5.293ValAla: 5.293 ± 0.943
0.814ValCys: 0.814 ± 0.553
4.886ValAsp: 4.886 ± 0.877
3.257ValGlu: 3.257 ± 2.222
1.629ValPhe: 1.629 ± 0.678
4.479ValGly: 4.479 ± 0.932
1.629ValHis: 1.629 ± 1.106
3.664ValIle: 3.664 ± 1.532
2.443ValLys: 2.443 ± 0.994
6.922ValLeu: 6.922 ± 2.063
1.221ValMet: 1.221 ± 0.516
3.257ValAsn: 3.257 ± 0.706
5.293ValPro: 5.293 ± 1.348
1.629ValGln: 1.629 ± 0.545
4.072ValArg: 4.072 ± 1.502
6.107ValSer: 6.107 ± 0.797
6.922ValThr: 6.922 ± 1.242
3.664ValVal: 3.664 ± 0.804
0.407ValTrp: 0.407 ± 0.462
1.629ValTyr: 1.629 ± 1.014
0.0ValXaa: 0.0 ± 0.0
Trp
0.407TrpAla: 0.407 ± 0.729
1.221TrpCys: 1.221 ± 0.934
0.407TrpAsp: 0.407 ± 0.277
0.407TrpGlu: 0.407 ± 0.277
1.629TrpPhe: 1.629 ± 0.625
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.814TrpLys: 0.814 ± 0.255
0.0TrpLeu: 0.0 ± 0.0
1.221TrpMet: 1.221 ± 0.627
1.221TrpAsn: 1.221 ± 0.83
0.0TrpPro: 0.0 ± 0.0
0.407TrpGln: 0.407 ± 0.609
0.407TrpArg: 0.407 ± 0.277
0.407TrpSer: 0.407 ± 0.311
0.0TrpThr: 0.0 ± 0.0
1.221TrpVal: 1.221 ± 0.673
0.407TrpTrp: 0.407 ± 0.311
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.221TyrAla: 1.221 ± 0.93
0.814TyrCys: 0.814 ± 0.553
4.479TyrAsp: 4.479 ± 0.862
1.629TyrGlu: 1.629 ± 0.678
0.814TyrPhe: 0.814 ± 0.255
2.85TyrGly: 2.85 ± 0.935
0.814TyrHis: 0.814 ± 0.255
3.257TyrIle: 3.257 ± 0.5
1.221TyrLys: 1.221 ± 0.497
1.629TyrLeu: 1.629 ± 1.017
0.814TyrMet: 0.814 ± 0.594
0.814TyrAsn: 0.814 ± 0.553
0.0TyrPro: 0.0 ± 0.0
1.221TyrGln: 1.221 ± 0.809
1.221TyrArg: 1.221 ± 0.616
3.257TyrSer: 3.257 ± 1.21
2.443TyrThr: 2.443 ± 1.009
1.629TyrVal: 1.629 ± 0.678
0.0TyrTrp: 0.0 ± 0.0
1.221TyrTyr: 1.221 ± 0.686
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2457 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski