Amino acid dipepetide frequency for Pisolithus tinctorius Marx 270

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.205AlaAla: 7.205 ± 0.045	1.395AlaCys: 1.395 ± 0.015	4.012AlaAsp: 4.012 ± 0.027	5.272AlaGlu: 5.272 ± 0.041	3.046AlaPhe: 3.046 ± 0.023	4.822AlaGly: 4.822 ± 0.031	2.114AlaHis: 2.114 ± 0.019	4.107AlaIle: 4.107 ± 0.03	3.737AlaLys: 3.737 ± 0.028	7.916AlaLeu: 7.916 ± 0.041	1.914AlaMet: 1.914 ± 0.018	2.713AlaAsn: 2.713 ± 0.02	4.271AlaPro: 4.271 ± 0.033	3.154AlaGln: 3.154 ± 0.024	4.939AlaArg: 4.939 ± 0.032	6.751AlaSer: 6.751 ± 0.038	4.891AlaThr: 4.891 ± 0.031	5.18AlaVal: 5.18 ± 0.028	1.207AlaTrp: 1.207 ± 0.016	1.993AlaTyr: 1.993 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.21CysAla: 1.21 ± 0.012	0.471CysCys: 0.471 ± 0.009	0.827CysAsp: 0.827 ± 0.011	0.9CysGlu: 0.9 ± 0.012	0.745CysPhe: 0.745 ± 0.011	1.159CysGly: 1.159 ± 0.016	0.581CysHis: 0.581 ± 0.011	1.017CysIle: 1.017 ± 0.012	0.826CysLys: 0.826 ± 0.012	1.706CysLeu: 1.706 ± 0.016	0.451CysMet: 0.451 ± 0.009	0.706CysAsn: 0.706 ± 0.011	1.022CysPro: 1.022 ± 0.016	0.684CysGln: 0.684 ± 0.011	1.046CysArg: 1.046 ± 0.013	1.363CysSer: 1.363 ± 0.015	1.144CysThr: 1.144 ± 0.014	1.054CysVal: 1.054 ± 0.014	0.288CysTrp: 0.288 ± 0.007	0.483CysTyr: 0.483 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.388AspAla: 4.388 ± 0.027	0.812AspCys: 0.812 ± 0.011	4.083AspAsp: 4.083 ± 0.036	4.122AspGlu: 4.122 ± 0.026	1.933AspPhe: 1.933 ± 0.018	3.861AspGly: 3.861 ± 0.027	1.429AspHis: 1.429 ± 0.015	3.081AspIle: 3.081 ± 0.022	2.231AspLys: 2.231 ± 0.021	4.882AspLeu: 4.882 ± 0.033	1.276AspMet: 1.276 ± 0.015	1.9AspAsn: 1.9 ± 0.02	3.289AspPro: 3.289 ± 0.024	1.631AspGln: 1.631 ± 0.015	2.88AspArg: 2.88 ± 0.029	3.918AspSer: 3.918 ± 0.026	3.058AspThr: 3.058 ± 0.026	4.03AspVal: 4.03 ± 0.027	0.889AspTrp: 0.889 ± 0.013	1.387AspTyr: 1.387 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.235GluAla: 5.235 ± 0.039	0.914GluCys: 0.914 ± 0.014	3.966GluAsp: 3.966 ± 0.027	5.724GluGlu: 5.724 ± 0.054	1.916GluPhe: 1.916 ± 0.021	3.778GluGly: 3.778 ± 0.028	1.526GluHis: 1.526 ± 0.017	2.778GluIle: 2.778 ± 0.022	3.009GluLys: 3.009 ± 0.029	5.443GluLeu: 5.443 ± 0.035	1.391GluMet: 1.391 ± 0.014	1.968GluAsn: 1.968 ± 0.018	2.602GluPro: 2.602 ± 0.021	2.321GluGln: 2.321 ± 0.021	4.245GluArg: 4.245 ± 0.036	3.976GluSer: 3.976 ± 0.027	2.962GluThr: 2.962 ± 0.021	3.893GluVal: 3.893 ± 0.03	1.098GluTrp: 1.098 ± 0.014	1.47GluTyr: 1.47 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.782PheAla: 2.782 ± 0.022	0.762PheCys: 0.762 ± 0.01	2.068PheAsp: 2.068 ± 0.018	1.93PheGlu: 1.93 ± 0.017	1.517PhePhe: 1.517 ± 0.017	2.408PheGly: 2.408 ± 0.023	1.102PheHis: 1.102 ± 0.013	1.769PheIle: 1.769 ± 0.017	1.494PheLys: 1.494 ± 0.016	3.442PheLeu: 3.442 ± 0.027	0.789PheMet: 0.789 ± 0.013	1.312PheAsn: 1.312 ± 0.017	2.16PhePro: 2.16 ± 0.018	1.338PheGln: 1.338 ± 0.014	2.051PheArg: 2.051 ± 0.019	3.042PheSer: 3.042 ± 0.023	2.104PheThr: 2.104 ± 0.019	2.461PheVal: 2.461 ± 0.021	0.606PheTrp: 0.606 ± 0.01	1.083PheTyr: 1.083 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.209GlyAla: 4.209 ± 0.025	1.078GlyCys: 1.078 ± 0.014	3.318GlyAsp: 3.318 ± 0.024	3.494GlyGlu: 3.494 ± 0.022	2.214GlyPhe: 2.214 ± 0.021	4.524GlyGly: 4.524 ± 0.039	1.878GlyHis: 1.878 ± 0.021	3.094GlyIle: 3.094 ± 0.021	3.455GlyLys: 3.455 ± 0.027	5.329GlyLeu: 5.329 ± 0.036	1.553GlyMet: 1.553 ± 0.017	2.241GlyAsn: 2.241 ± 0.019	3.157GlyPro: 3.157 ± 0.026	2.17GlyGln: 2.17 ± 0.019	3.804GlyArg: 3.804 ± 0.029	5.332GlySer: 5.332 ± 0.035	3.796GlyThr: 3.796 ± 0.025	4.137GlyVal: 4.137 ± 0.031	1.055GlyTrp: 1.055 ± 0.014	1.667GlyTyr: 1.667 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	2.304HisAla: 2.304 ± 0.018	0.575HisCys: 0.575 ± 0.01	1.479HisAsp: 1.479 ± 0.015	1.436HisGlu: 1.436 ± 0.015	1.129HisPhe: 1.129 ± 0.014	1.781HisGly: 1.781 ± 0.018	1.072HisHis: 1.072 ± 0.014	1.519HisIle: 1.519 ± 0.015	1.134HisLys: 1.134 ± 0.015	2.933HisLeu: 2.933 ± 0.024	0.649HisMet: 0.649 ± 0.01	0.969HisAsn: 0.969 ± 0.014	2.155HisPro: 2.155 ± 0.022	1.089HisGln: 1.089 ± 0.014	1.768HisArg: 1.768 ± 0.016	2.375HisSer: 2.375 ± 0.02	1.716HisThr: 1.716 ± 0.019	1.912HisVal: 1.912 ± 0.017	0.45HisTrp: 0.45 ± 0.009	0.796HisTyr: 0.796 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.968IleAla: 3.968 ± 0.025	0.956IleCys: 0.956 ± 0.012	2.691IleAsp: 2.691 ± 0.023	2.579IleGlu: 2.579 ± 0.02	1.845IlePhe: 1.845 ± 0.017	2.735IleGly: 2.735 ± 0.025	1.472IleHis: 1.472 ± 0.016	2.418IleIle: 2.418 ± 0.022	2.092IleLys: 2.092 ± 0.018	4.66IleLeu: 4.66 ± 0.03	1.019IleMet: 1.019 ± 0.012	1.736IleAsn: 1.736 ± 0.018	3.275IlePro: 3.275 ± 0.023	1.866IleGln: 1.866 ± 0.017	2.841IleArg: 2.841 ± 0.026	3.935IleSer: 3.935 ± 0.025	2.846IleThr: 2.846 ± 0.02	3.196IleVal: 3.196 ± 0.026	0.759IleTrp: 0.759 ± 0.011	1.299IleTyr: 1.299 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.124LysAla: 4.124 ± 0.035	0.764LysCys: 0.764 ± 0.011	2.554LysAsp: 2.554 ± 0.022	3.033LysGlu: 3.033 ± 0.023	1.419LysPhe: 1.419 ± 0.017	2.851LysGly: 2.851 ± 0.023	1.232LysHis: 1.232 ± 0.013	2.06LysIle: 2.06 ± 0.017	2.888LysLys: 2.888 ± 0.031	4.077LysLeu: 4.077 ± 0.029	0.975LysMet: 0.975 ± 0.013	1.474LysAsn: 1.474 ± 0.017	2.413LysPro: 2.413 ± 0.024	1.753LysGln: 1.753 ± 0.017	3.362LysArg: 3.362 ± 0.032	3.172LysSer: 3.172 ± 0.025	2.574LysThr: 2.574 ± 0.021	2.954LysVal: 2.954 ± 0.02	0.777LysTrp: 0.777 ± 0.012	1.248LysTyr: 1.248 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.737LeuAla: 7.737 ± 0.035	1.791LeuCys: 1.791 ± 0.019	5.185LeuAsp: 5.185 ± 0.027	5.654LeuGlu: 5.654 ± 0.039	3.483LeuPhe: 3.483 ± 0.027	5.396LeuGly: 5.396 ± 0.03	3.036LeuHis: 3.036 ± 0.022	3.896LeuIle: 3.896 ± 0.03	4.027LeuLys: 4.027 ± 0.023	8.877LeuLeu: 8.877 ± 0.054	1.865LeuMet: 1.865 ± 0.017	3.009LeuAsn: 3.009 ± 0.024	6.123LeuPro: 6.123 ± 0.036	4.106LeuGln: 4.106 ± 0.026	6.053LeuArg: 6.053 ± 0.033	7.933LeuSer: 7.933 ± 0.042	5.264LeuThr: 5.264 ± 0.03	5.849LeuVal: 5.849 ± 0.035	1.397LeuTrp: 1.397 ± 0.014	2.414LeuTyr: 2.414 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.016MetAla: 2.016 ± 0.018	0.382MetCys: 0.382 ± 0.008	1.338MetAsp: 1.338 ± 0.014	1.369MetGlu: 1.369 ± 0.016	0.784MetPhe: 0.784 ± 0.012	1.236MetGly: 1.236 ± 0.015	0.663MetHis: 0.663 ± 0.011	1.005MetIle: 1.005 ± 0.014	1.084MetLys: 1.084 ± 0.015	2.027MetLeu: 2.027 ± 0.016	0.539MetMet: 0.539 ± 0.01	0.737MetAsn: 0.737 ± 0.01	1.327MetPro: 1.327 ± 0.015	0.932MetGln: 0.932 ± 0.011	1.343MetArg: 1.343 ± 0.016	2.115MetSer: 2.115 ± 0.018	1.314MetThr: 1.314 ± 0.015	1.392MetVal: 1.392 ± 0.016	0.337MetTrp: 0.337 ± 0.008	0.551MetTyr: 0.551 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.895AsnAla: 2.895 ± 0.02	0.541AsnCys: 0.541 ± 0.01	1.911AsnAsp: 1.911 ± 0.017	1.904AsnGlu: 1.904 ± 0.018	1.29AsnPhe: 1.29 ± 0.014	2.296AsnGly: 2.296 ± 0.021	0.962AsnHis: 0.962 ± 0.013	1.925AsnIle: 1.925 ± 0.02	1.485AsnLys: 1.485 ± 0.016	3.217AsnLeu: 3.217 ± 0.024	0.824AsnMet: 0.824 ± 0.012	1.405AsnAsn: 1.405 ± 0.018	2.265AsnPro: 2.265 ± 0.019	1.206AsnGln: 1.206 ± 0.016	1.723AsnArg: 1.723 ± 0.018	2.642AsnSer: 2.642 ± 0.021	2.113AsnThr: 2.113 ± 0.018	2.44AsnVal: 2.44 ± 0.02	0.524AsnTrp: 0.524 ± 0.01	0.927AsnTyr: 0.927 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.725ProAla: 4.725 ± 0.038	0.941ProCys: 0.941 ± 0.013	3.231ProAsp: 3.231 ± 0.025	3.311ProGlu: 3.311 ± 0.025	2.152ProPhe: 2.152 ± 0.02	3.587ProGly: 3.587 ± 0.031	1.748ProHis: 1.748 ± 0.016	2.571ProIle: 2.571 ± 0.02	2.444ProLys: 2.444 ± 0.02	5.454ProLeu: 5.454 ± 0.03	1.112ProMet: 1.112 ± 0.012	2.094ProAsn: 2.094 ± 0.02	5.835ProPro: 5.835 ± 0.068	2.345ProGln: 2.345 ± 0.022	3.456ProArg: 3.456 ± 0.028	7.102ProSer: 7.102 ± 0.05	4.181ProThr: 4.181 ± 0.031	3.844ProVal: 3.844 ± 0.029	0.785ProTrp: 0.785 ± 0.011	1.555ProTyr: 1.555 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.303GlnAla: 3.303 ± 0.024	0.684GlnCys: 0.684 ± 0.012	1.888GlnAsp: 1.888 ± 0.016	2.321GlnGlu: 2.321 ± 0.02	1.207GlnPhe: 1.207 ± 0.013	2.215GlnGly: 2.215 ± 0.021	1.181GlnHis: 1.181 ± 0.015	1.731GlnIle: 1.731 ± 0.016	1.751GlnLys: 1.751 ± 0.019	3.694GlnLeu: 3.694 ± 0.024	0.922GlnMet: 0.922 ± 0.014	1.329GlnAsn: 1.329 ± 0.013	2.378GlnPro: 2.378 ± 0.026	1.931GlnGln: 1.931 ± 0.026	2.631GlnArg: 2.631 ± 0.025	3.114GlnSer: 3.114 ± 0.027	2.197GlnThr: 2.197 ± 0.019	2.477GlnVal: 2.477 ± 0.021	0.641GlnTrp: 0.641 ± 0.01	1.063GlnTyr: 1.063 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.92ArgAla: 4.92 ± 0.035	1.126ArgCys: 1.126 ± 0.015	3.12ArgAsp: 3.12 ± 0.026	3.879ArgGlu: 3.879 ± 0.035	2.149ArgPhe: 2.149 ± 0.019	3.553ArgGly: 3.553 ± 0.028	1.76ArgHis: 1.76 ± 0.016	2.997ArgIle: 2.997 ± 0.026	3.302ArgLys: 3.302 ± 0.024	5.607ArgLeu: 5.607 ± 0.032	1.479ArgMet: 1.479 ± 0.015	2.075ArgAsn: 2.075 ± 0.019	3.46ArgPro: 3.46 ± 0.029	2.412ArgGln: 2.412 ± 0.021	5.002ArgArg: 5.002 ± 0.035	5.162ArgSer: 5.162 ± 0.038	3.586ArgThr: 3.586 ± 0.025	3.883ArgVal: 3.883 ± 0.03	1.061ArgTrp: 1.061 ± 0.014	1.665ArgTyr: 1.665 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.469SerAla: 6.469 ± 0.038	1.392SerCys: 1.392 ± 0.016	4.303SerAsp: 4.303 ± 0.026	4.077SerGlu: 4.077 ± 0.029	2.946SerPhe: 2.946 ± 0.025	5.444SerGly: 5.444 ± 0.032	2.544SerHis: 2.544 ± 0.019	3.862SerIle: 3.862 ± 0.027	3.553SerLys: 3.553 ± 0.025	7.825SerLeu: 7.825 ± 0.044	1.833SerMet: 1.833 ± 0.016	2.955SerAsn: 2.955 ± 0.023	6.062SerPro: 6.062 ± 0.047	3.436SerGln: 3.436 ± 0.027	5.201SerArg: 5.201 ± 0.037	9.384SerSer: 9.384 ± 0.063	5.834SerThr: 5.834 ± 0.04	5.102SerVal: 5.102 ± 0.031	1.151SerTrp: 1.151 ± 0.015	1.998SerTyr: 1.998 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.82ThrAla: 4.82 ± 0.026	1.136ThrCys: 1.136 ± 0.013	2.847ThrAsp: 2.847 ± 0.021	2.915ThrGlu: 2.915 ± 0.019	2.339ThrPhe: 2.339 ± 0.021	3.625ThrGly: 3.625 ± 0.026	1.688ThrHis: 1.688 ± 0.017	3.054ThrIle: 3.054 ± 0.021	2.43ThrLys: 2.43 ± 0.02	5.744ThrLeu: 5.744 ± 0.032	1.296ThrMet: 1.296 ± 0.014	2.002ThrAsn: 2.002 ± 0.02	4.434ThrPro: 4.434 ± 0.038	2.153ThrGln: 2.153 ± 0.02	3.467ThrArg: 3.467 ± 0.023	5.713ThrSer: 5.713 ± 0.037	4.253ThrThr: 4.253 ± 0.027	3.741ThrVal: 3.741 ± 0.022	0.856ThrTrp: 0.856 ± 0.011	1.509ThrTyr: 1.509 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.177ValAla: 5.177 ± 0.026	1.172ValCys: 1.172 ± 0.015	3.764ValAsp: 3.764 ± 0.027	4.001ValGlu: 4.001 ± 0.028	2.442ValPhe: 2.442 ± 0.021	3.822ValGly: 3.822 ± 0.029	1.897ValHis: 1.897 ± 0.02	3.212ValIle: 3.212 ± 0.022	2.868ValLys: 2.868 ± 0.023	6.07ValLeu: 6.07 ± 0.035	1.536ValMet: 1.536 ± 0.017	2.213ValAsn: 2.213 ± 0.018	4.032ValPro: 4.032 ± 0.027	2.579ValGln: 2.579 ± 0.02	3.84ValArg: 3.84 ± 0.027	5.097ValSer: 5.097 ± 0.031	3.77ValThr: 3.77 ± 0.021	4.785ValVal: 4.785 ± 0.029	1.013ValTrp: 1.013 ± 0.014	1.7ValTyr: 1.7 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.178TrpAla: 1.178 ± 0.014	0.289TrpCys: 0.289 ± 0.007	0.914TrpAsp: 0.914 ± 0.013	0.95TrpGlu: 0.95 ± 0.012	0.585TrpPhe: 0.585 ± 0.011	0.79TrpGly: 0.79 ± 0.01	0.474TrpHis: 0.474 ± 0.01	0.748TrpIle: 0.748 ± 0.011	0.865TrpLys: 0.865 ± 0.011	1.515TrpLeu: 1.515 ± 0.018	0.464TrpMet: 0.464 ± 0.009	0.644TrpAsn: 0.644 ± 0.011	0.724TrpPro: 0.724 ± 0.011	0.574TrpGln: 0.574 ± 0.01	1.001TrpArg: 1.001 ± 0.012	1.182TrpSer: 1.182 ± 0.013	0.947TrpThr: 0.947 ± 0.013	0.963TrpVal: 0.963 ± 0.012	0.322TrpTrp: 0.322 ± 0.007	0.487TrpTyr: 0.487 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.973TyrAla: 1.973 ± 0.018	0.499TyrCys: 0.499 ± 0.009	1.584TyrAsp: 1.584 ± 0.016	1.343TyrGlu: 1.343 ± 0.014	1.079TyrPhe: 1.079 ± 0.014	1.621TyrGly: 1.621 ± 0.016	0.882TyrHis: 0.882 ± 0.012	1.343TyrIle: 1.343 ± 0.015	1.026TyrLys: 1.026 ± 0.012	2.678TyrLeu: 2.678 ± 0.023	0.605TyrMet: 0.605 ± 0.009	1.014TyrAsn: 1.014 ± 0.014	1.49TyrPro: 1.49 ± 0.017	0.98TyrGln: 0.98 ± 0.012	1.544TyrArg: 1.544 ± 0.015	2.062TyrSer: 2.062 ± 0.017	1.474TyrThr: 1.474 ± 0.017	1.699TyrVal: 1.699 ± 0.018	0.397TyrTrp: 0.397 ± 0.008	0.823TyrTyr: 0.823 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 22409 proteins (6502442 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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