Amino acid dipepetide frequency for Parabacteroides johnsonii CL02T12C29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.687AlaAla: 5.687 ± 0.09	0.939AlaCys: 0.939 ± 0.027	4.24AlaAsp: 4.24 ± 0.054	4.789AlaGlu: 4.789 ± 0.07	3.25AlaPhe: 3.25 ± 0.049	5.553AlaGly: 5.553 ± 0.073	1.111AlaHis: 1.111 ± 0.03	4.805AlaIle: 4.805 ± 0.074	4.007AlaLys: 4.007 ± 0.07	6.708AlaLeu: 6.708 ± 0.082	1.864AlaMet: 1.864 ± 0.038	3.151AlaAsn: 3.151 ± 0.045	2.35AlaPro: 2.35 ± 0.043	2.379AlaGln: 2.379 ± 0.041	3.05AlaArg: 3.05 ± 0.055	4.371AlaSer: 4.371 ± 0.064	3.852AlaThr: 3.852 ± 0.049	4.856AlaVal: 4.856 ± 0.065	0.827AlaTrp: 0.827 ± 0.028	2.909AlaTyr: 2.909 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.72CysAla: 0.72 ± 0.021	0.201CysCys: 0.201 ± 0.013	0.6CysAsp: 0.6 ± 0.022	0.605CysGlu: 0.605 ± 0.021	0.621CysPhe: 0.621 ± 0.022	0.929CysGly: 0.929 ± 0.031	0.301CysHis: 0.301 ± 0.013	0.843CysIle: 0.843 ± 0.024	0.663CysLys: 0.663 ± 0.025	1.166CysLeu: 1.166 ± 0.034	0.357CysMet: 0.357 ± 0.015	0.562CysAsn: 0.562 ± 0.023	0.533CysPro: 0.533 ± 0.022	0.33CysGln: 0.33 ± 0.016	0.589CysArg: 0.589 ± 0.023	0.787CysSer: 0.787 ± 0.022	0.643CysThr: 0.643 ± 0.02	0.731CysVal: 0.731 ± 0.024	0.171CysTrp: 0.171 ± 0.01	0.505CysTyr: 0.505 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	3.897AspAla: 3.897 ± 0.063	0.611AspCys: 0.611 ± 0.023	2.625AspAsp: 2.625 ± 0.048	3.872AspGlu: 3.872 ± 0.065	2.976AspPhe: 2.976 ± 0.045	4.159AspGly: 4.159 ± 0.066	0.92AspHis: 0.92 ± 0.028	4.192AspIle: 4.192 ± 0.052	4.102AspLys: 4.102 ± 0.059	4.811AspLeu: 4.811 ± 0.054	1.661AspMet: 1.661 ± 0.036	2.808AspAsn: 2.808 ± 0.054	2.173AspPro: 2.173 ± 0.044	1.441AspGln: 1.441 ± 0.039	2.756AspArg: 2.756 ± 0.046	2.994AspSer: 2.994 ± 0.057	2.708AspThr: 2.708 ± 0.049	3.542AspVal: 3.542 ± 0.051	0.888AspTrp: 0.888 ± 0.031	2.852AspTyr: 2.852 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	5.196GluAla: 5.196 ± 0.067	0.605GluCys: 0.605 ± 0.023	3.293GluAsp: 3.293 ± 0.052	5.277GluGlu: 5.277 ± 0.076	2.346GluPhe: 2.346 ± 0.04	4.245GluGly: 4.245 ± 0.059	1.154GluHis: 1.154 ± 0.028	4.679GluIle: 4.679 ± 0.069	5.379GluLys: 5.379 ± 0.073	6.139GluLeu: 6.139 ± 0.075	2.064GluMet: 2.064 ± 0.039	3.523GluAsn: 3.523 ± 0.054	1.861GluPro: 1.861 ± 0.036	2.668GluGln: 2.668 ± 0.045	3.258GluArg: 3.258 ± 0.062	3.202GluSer: 3.202 ± 0.044	3.463GluThr: 3.463 ± 0.058	4.376GluVal: 4.376 ± 0.063	0.876GluTrp: 0.876 ± 0.026	2.784GluTyr: 2.784 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.045PheAla: 3.045 ± 0.057	0.691PheCys: 0.691 ± 0.02	2.861PheAsp: 2.861 ± 0.044	2.532PheGlu: 2.532 ± 0.047	2.312PhePhe: 2.312 ± 0.046	3.336PheGly: 3.336 ± 0.056	0.902PheHis: 0.902 ± 0.029	3.13PheIle: 3.13 ± 0.052	2.475PheLys: 2.475 ± 0.047	4.185PheLeu: 4.185 ± 0.059	1.272PheMet: 1.272 ± 0.029	2.386PheAsn: 2.386 ± 0.043	1.821PhePro: 1.821 ± 0.041	1.332PheGln: 1.332 ± 0.033	2.297PheArg: 2.297 ± 0.042	3.384PheSer: 3.384 ± 0.045	2.877PheThr: 2.877 ± 0.052	2.999PheVal: 2.999 ± 0.048	0.586PheTrp: 0.586 ± 0.024	2.037PheTyr: 2.037 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.386GlyAla: 4.386 ± 0.071	0.93GlyCys: 0.93 ± 0.027	3.576GlyAsp: 3.576 ± 0.054	4.266GlyGlu: 4.266 ± 0.065	3.229GlyPhe: 3.229 ± 0.055	4.795GlyGly: 4.795 ± 0.077	1.268GlyHis: 1.268 ± 0.034	5.256GlyIle: 5.256 ± 0.071	5.654GlyLys: 5.654 ± 0.052	5.902GlyLeu: 5.902 ± 0.078	2.11GlyMet: 2.11 ± 0.047	3.622GlyAsn: 3.622 ± 0.062	1.396GlyPro: 1.396 ± 0.032	2.208GlyGln: 2.208 ± 0.042	3.002GlyArg: 3.002 ± 0.051	4.072GlySer: 4.072 ± 0.065	4.234GlyThr: 4.234 ± 0.062	4.699GlyVal: 4.699 ± 0.069	1.046GlyTrp: 1.046 ± 0.032	3.498GlyTyr: 3.498 ± 0.072	0.0GlyXaa: 0.0 ± 0.0
His	1.153HisAla: 1.153 ± 0.029	0.274HisCys: 0.274 ± 0.015	0.851HisAsp: 0.851 ± 0.03	1.009HisGlu: 1.009 ± 0.031	0.973HisPhe: 0.973 ± 0.03	1.179HisGly: 1.179 ± 0.03	0.454HisHis: 0.454 ± 0.023	1.439HisIle: 1.439 ± 0.032	1.005HisLys: 1.005 ± 0.027	1.807HisLeu: 1.807 ± 0.043	0.361HisMet: 0.361 ± 0.015	0.883HisAsn: 0.883 ± 0.027	1.057HisPro: 1.057 ± 0.029	0.603HisGln: 0.603 ± 0.021	0.909HisArg: 0.909 ± 0.026	1.105HisSer: 1.105 ± 0.031	1.035HisThr: 1.035 ± 0.027	1.019HisVal: 1.019 ± 0.031	0.254HisTrp: 0.254 ± 0.012	0.884HisTyr: 0.884 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.123IleAla: 5.123 ± 0.069	0.947IleCys: 0.947 ± 0.022	4.137IleAsp: 4.137 ± 0.053	4.403IleGlu: 4.403 ± 0.064	2.744IlePhe: 2.744 ± 0.052	4.849IleGly: 4.849 ± 0.078	1.323IleHis: 1.323 ± 0.032	4.325IleIle: 4.325 ± 0.067	4.048IleLys: 4.048 ± 0.062	5.976IleLeu: 5.976 ± 0.088	1.514IleMet: 1.514 ± 0.037	3.281IleAsn: 3.281 ± 0.06	3.206IlePro: 3.206 ± 0.043	2.306IleGln: 2.306 ± 0.041	3.75IleArg: 3.75 ± 0.056	4.597IleSer: 4.597 ± 0.058	3.961IleThr: 3.961 ± 0.055	4.407IleVal: 4.407 ± 0.065	0.729IleTrp: 0.729 ± 0.026	2.648IleTyr: 2.648 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.935LysAla: 4.935 ± 0.071	0.518LysCys: 0.518 ± 0.02	4.127LysAsp: 4.127 ± 0.054	5.901LysGlu: 5.901 ± 0.075	2.104LysPhe: 2.104 ± 0.043	4.629LysGly: 4.629 ± 0.065	1.12LysHis: 1.12 ± 0.027	4.183LysIle: 4.183 ± 0.061	5.043LysLys: 5.043 ± 0.074	5.257LysLeu: 5.257 ± 0.072	2.009LysMet: 2.009 ± 0.036	3.487LysAsn: 3.487 ± 0.062	2.249LysPro: 2.249 ± 0.04	2.672LysGln: 2.672 ± 0.046	3.136LysArg: 3.136 ± 0.053	3.277LysSer: 3.277 ± 0.055	3.473LysThr: 3.473 ± 0.046	4.382LysVal: 4.382 ± 0.058	0.729LysTrp: 0.729 ± 0.029	2.882LysTyr: 2.882 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	6.494LeuAla: 6.494 ± 0.08	1.277LeuCys: 1.277 ± 0.033	4.904LeuAsp: 4.904 ± 0.062	5.139LeuGlu: 5.139 ± 0.067	4.859LeuPhe: 4.859 ± 0.074	5.515LeuGly: 5.515 ± 0.077	1.717LeuHis: 1.717 ± 0.039	5.562LeuIle: 5.562 ± 0.081	6.175LeuLys: 6.175 ± 0.07	9.532LeuLeu: 9.532 ± 0.115	2.407LeuMet: 2.407 ± 0.043	4.653LeuAsn: 4.653 ± 0.065	4.181LeuPro: 4.181 ± 0.058	3.363LeuGln: 3.363 ± 0.056	4.178LeuArg: 4.178 ± 0.059	6.756LeuSer: 6.756 ± 0.083	5.144LeuThr: 5.144 ± 0.052	5.361LeuVal: 5.361 ± 0.072	1.003LeuTrp: 1.003 ± 0.03	3.827LeuTyr: 3.827 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	2.1MetAla: 2.1 ± 0.049	0.252MetCys: 0.252 ± 0.014	1.533MetAsp: 1.533 ± 0.031	1.936MetGlu: 1.936 ± 0.037	1.062MetPhe: 1.062 ± 0.035	1.816MetGly: 1.816 ± 0.038	0.449MetHis: 0.449 ± 0.016	1.623MetIle: 1.623 ± 0.04	2.406MetLys: 2.406 ± 0.04	2.473MetLeu: 2.473 ± 0.051	0.765MetMet: 0.765 ± 0.029	1.582MetAsn: 1.582 ± 0.032	1.112MetPro: 1.112 ± 0.026	1.138MetGln: 1.138 ± 0.029	1.241MetArg: 1.241 ± 0.029	1.494MetSer: 1.494 ± 0.038	1.385MetThr: 1.385 ± 0.036	1.612MetVal: 1.612 ± 0.037	0.226MetTrp: 0.226 ± 0.014	0.862MetTyr: 0.862 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.278AsnAla: 3.278 ± 0.057	0.526AsnCys: 0.526 ± 0.02	2.586AsnAsp: 2.586 ± 0.044	2.997AsnGlu: 2.997 ± 0.055	2.225AsnPhe: 2.225 ± 0.044	3.857AsnGly: 3.857 ± 0.073	0.895AsnHis: 0.895 ± 0.026	3.725AsnIle: 3.725 ± 0.07	3.163AsnLys: 3.163 ± 0.053	4.373AsnLeu: 4.373 ± 0.058	1.372AsnMet: 1.372 ± 0.034	2.561AsnAsn: 2.561 ± 0.052	2.474AsnPro: 2.474 ± 0.045	1.545AsnGln: 1.545 ± 0.036	2.601AsnArg: 2.601 ± 0.051	2.747AsnSer: 2.747 ± 0.047	2.756AsnThr: 2.756 ± 0.048	3.192AsnVal: 3.192 ± 0.052	0.708AsnTrp: 0.708 ± 0.024	2.243AsnTyr: 2.243 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	2.908ProAla: 2.908 ± 0.051	0.337ProCys: 0.337 ± 0.015	2.81ProAsp: 2.81 ± 0.05	3.662ProGlu: 3.662 ± 0.057	2.039ProPhe: 2.039 ± 0.042	2.622ProGly: 2.622 ± 0.045	0.698ProHis: 0.698 ± 0.025	2.321ProIle: 2.321 ± 0.037	2.0ProLys: 2.0 ± 0.037	3.332ProLeu: 3.332 ± 0.051	0.916ProMet: 0.916 ± 0.027	1.705ProAsn: 1.705 ± 0.039	0.828ProPro: 0.828 ± 0.028	1.222ProGln: 1.222 ± 0.028	1.286ProArg: 1.286 ± 0.032	2.324ProSer: 2.324 ± 0.043	1.914ProThr: 1.914 ± 0.041	3.307ProVal: 3.307 ± 0.043	0.456ProTrp: 0.456 ± 0.018	1.695ProTyr: 1.695 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.47GlnAla: 2.47 ± 0.044	0.293GlnCys: 0.293 ± 0.015	1.689GlnAsp: 1.689 ± 0.036	2.286GlnGlu: 2.286 ± 0.041	1.351GlnPhe: 1.351 ± 0.03	1.955GlnGly: 1.955 ± 0.036	0.595GlnHis: 0.595 ± 0.023	2.384GlnIle: 2.384 ± 0.047	2.5GlnLys: 2.5 ± 0.042	3.249GlnLeu: 3.249 ± 0.047	0.977GlnMet: 0.977 ± 0.025	1.706GlnAsn: 1.706 ± 0.042	1.278GlnPro: 1.278 ± 0.035	1.535GlnGln: 1.535 ± 0.039	1.532GlnArg: 1.532 ± 0.033	1.881GlnSer: 1.881 ± 0.036	2.05GlnThr: 2.05 ± 0.036	2.259GlnVal: 2.259 ± 0.04	0.454GlnTrp: 0.454 ± 0.018	1.504GlnTyr: 1.504 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.753ArgAla: 2.753 ± 0.047	0.468ArgCys: 0.468 ± 0.018	2.229ArgAsp: 2.229 ± 0.047	3.24ArgGlu: 3.24 ± 0.055	2.407ArgPhe: 2.407 ± 0.041	2.442ArgGly: 2.442 ± 0.046	0.945ArgHis: 0.945 ± 0.027	3.762ArgIle: 3.762 ± 0.05	3.48ArgLys: 3.48 ± 0.051	4.654ArgLeu: 4.654 ± 0.068	1.538ArgMet: 1.538 ± 0.033	2.438ArgAsn: 2.438 ± 0.046	1.759ArgPro: 1.759 ± 0.037	1.869ArgGln: 1.869 ± 0.034	2.371ArgArg: 2.371 ± 0.046	2.521ArgSer: 2.521 ± 0.045	2.529ArgThr: 2.529 ± 0.044	2.712ArgVal: 2.712 ± 0.05	0.65ArgTrp: 0.65 ± 0.025	2.291ArgTyr: 2.291 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.161SerAla: 4.161 ± 0.068	0.782SerCys: 0.782 ± 0.027	3.469SerAsp: 3.469 ± 0.051	3.634SerGlu: 3.634 ± 0.055	3.416SerPhe: 3.416 ± 0.049	4.719SerGly: 4.719 ± 0.071	1.142SerHis: 1.142 ± 0.028	4.18SerIle: 4.18 ± 0.062	3.192SerLys: 3.192 ± 0.048	5.997SerLeu: 5.997 ± 0.078	1.449SerMet: 1.449 ± 0.035	2.594SerAsn: 2.594 ± 0.049	2.398SerPro: 2.398 ± 0.042	1.716SerGln: 1.716 ± 0.036	2.83SerArg: 2.83 ± 0.047	3.785SerSer: 3.785 ± 0.065	3.147SerThr: 3.147 ± 0.053	4.319SerVal: 4.319 ± 0.056	0.787SerTrp: 0.787 ± 0.025	2.851SerTyr: 2.851 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	3.955ThrAla: 3.955 ± 0.063	0.57ThrCys: 0.57 ± 0.018	3.536ThrAsp: 3.536 ± 0.059	3.446ThrGlu: 3.446 ± 0.056	2.806ThrPhe: 2.806 ± 0.042	4.519ThrGly: 4.519 ± 0.059	1.015ThrHis: 1.015 ± 0.029	3.89ThrIle: 3.89 ± 0.057	2.772ThrLys: 2.772 ± 0.048	5.318ThrLeu: 5.318 ± 0.06	1.182ThrMet: 1.182 ± 0.029	2.494ThrAsn: 2.494 ± 0.047	2.762ThrPro: 2.762 ± 0.052	1.658ThrGln: 1.658 ± 0.034	2.256ThrArg: 2.256 ± 0.041	3.222ThrSer: 3.222 ± 0.052	3.148ThrThr: 3.148 ± 0.057	4.076ThrVal: 4.076 ± 0.053	0.637ThrTrp: 0.637 ± 0.025	2.339ThrTyr: 2.339 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	4.834ValAla: 4.834 ± 0.069	0.956ValCys: 0.956 ± 0.027	3.606ValAsp: 3.606 ± 0.058	4.148ValGlu: 4.148 ± 0.061	3.003ValPhe: 3.003 ± 0.045	4.116ValGly: 4.116 ± 0.066	1.073ValHis: 1.073 ± 0.032	4.393ValIle: 4.393 ± 0.062	4.336ValLys: 4.336 ± 0.058	5.97ValLeu: 5.97 ± 0.065	1.681ValMet: 1.681 ± 0.037	3.201ValAsn: 3.201 ± 0.049	2.649ValPro: 2.649 ± 0.048	1.952ValGln: 1.952 ± 0.037	3.119ValArg: 3.119 ± 0.053	4.588ValSer: 4.588 ± 0.059	3.918ValThr: 3.918 ± 0.059	4.602ValVal: 4.602 ± 0.072	0.8ValTrp: 0.8 ± 0.025	2.709ValTyr: 2.709 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.714TrpAla: 0.714 ± 0.024	0.153TrpCys: 0.153 ± 0.011	0.747TrpAsp: 0.747 ± 0.026	0.817TrpGlu: 0.817 ± 0.027	0.579TrpPhe: 0.579 ± 0.022	0.888TrpGly: 0.888 ± 0.031	0.287TrpHis: 0.287 ± 0.014	0.808TrpIle: 0.808 ± 0.023	0.938TrpLys: 0.938 ± 0.031	1.206TrpLeu: 1.206 ± 0.03	0.434TrpMet: 0.434 ± 0.019	0.778TrpAsn: 0.778 ± 0.03	0.31TrpPro: 0.31 ± 0.015	0.522TrpGln: 0.522 ± 0.02	0.565TrpArg: 0.565 ± 0.021	0.693TrpSer: 0.693 ± 0.026	0.696TrpThr: 0.696 ± 0.027	0.746TrpVal: 0.746 ± 0.025	0.188TrpTrp: 0.188 ± 0.013	0.559TrpTyr: 0.559 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.89TyrAla: 2.89 ± 0.043	0.527TyrCys: 0.527 ± 0.02	2.566TyrAsp: 2.566 ± 0.051	2.43TyrGlu: 2.43 ± 0.04	2.161TyrPhe: 2.161 ± 0.046	3.026TyrGly: 3.026 ± 0.058	0.885TyrHis: 0.885 ± 0.025	2.775TyrIle: 2.775 ± 0.047	2.775TyrLys: 2.775 ± 0.042	3.989TyrLeu: 3.989 ± 0.061	1.132TyrMet: 1.132 ± 0.026	2.411TyrAsn: 2.411 ± 0.044	1.985TyrPro: 1.985 ± 0.038	1.49TyrGln: 1.49 ± 0.031	2.333TyrArg: 2.333 ± 0.045	2.766TyrSer: 2.766 ± 0.055	2.669TyrThr: 2.669 ± 0.054	2.456TyrVal: 2.456 ± 0.041	0.614TyrTrp: 0.614 ± 0.022	2.156TyrTyr: 2.156 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3736 proteins (1374269 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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