Amino acid dipepetide frequency for Wenling tombus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.362AlaAla: 7.362 ± 4.511
0.0AlaCys: 0.0 ± 0.0
2.454AlaAsp: 2.454 ± 0.315
3.681AlaGlu: 3.681 ± 1.364
2.454AlaPhe: 2.454 ± 1.468
3.681AlaGly: 3.681 ± 1.364
0.0AlaHis: 0.0 ± 0.0
3.681AlaIle: 3.681 ± 0.419
4.908AlaLys: 4.908 ± 1.153
2.454AlaLeu: 2.454 ± 1.468
2.454AlaMet: 2.454 ± 1.468
3.681AlaAsn: 3.681 ± 3.147
3.681AlaPro: 3.681 ± 1.364
2.454AlaGln: 2.454 ± 2.098
6.135AlaArg: 6.135 ± 1.887
4.908AlaSer: 4.908 ± 0.63
3.681AlaThr: 3.681 ± 2.202
8.589AlaVal: 8.589 ± 7.343
2.454AlaTrp: 2.454 ± 2.098
6.135AlaTyr: 6.135 ± 1.887
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.227CysCys: 1.227 ± 1.049
2.454CysAsp: 2.454 ± 1.468
2.454CysGlu: 2.454 ± 0.315
1.227CysPhe: 1.227 ± 0.734
1.227CysGly: 1.227 ± 1.049
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
4.908CysLeu: 4.908 ± 1.153
0.0CysMet: 0.0 ± 0.0
1.227CysAsn: 1.227 ± 1.049
1.227CysPro: 1.227 ± 1.049
2.454CysGln: 2.454 ± 1.468
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
3.681CysVal: 3.681 ± 1.364
0.0CysTrp: 0.0 ± 0.0
2.454CysTyr: 2.454 ± 0.315
0.0CysXaa: 0.0 ± 0.0
Asp
2.454AspAla: 2.454 ± 1.468
1.227AspCys: 1.227 ± 1.049
2.454AspAsp: 2.454 ± 1.468
6.135AspGlu: 6.135 ± 1.679
1.227AspPhe: 1.227 ± 0.734
1.227AspGly: 1.227 ± 0.734
4.908AspHis: 4.908 ± 0.63
3.681AspIle: 3.681 ± 0.419
1.227AspLys: 1.227 ± 0.734
2.454AspLeu: 2.454 ± 0.315
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
2.454AspPro: 2.454 ± 0.315
2.454AspGln: 2.454 ± 1.468
2.454AspArg: 2.454 ± 1.468
2.454AspSer: 2.454 ± 1.468
3.681AspThr: 3.681 ± 1.364
2.454AspVal: 2.454 ± 1.468
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.681GluAla: 3.681 ± 2.202
0.0GluCys: 0.0 ± 0.0
2.454GluAsp: 2.454 ± 0.315
3.681GluGlu: 3.681 ± 3.147
2.454GluPhe: 2.454 ± 1.468
2.454GluGly: 2.454 ± 0.315
4.908GluHis: 4.908 ± 2.936
2.454GluIle: 2.454 ± 1.468
1.227GluLys: 1.227 ± 0.734
2.454GluLeu: 2.454 ± 1.468
0.0GluMet: 0.0 ± 0.0
2.454GluAsn: 2.454 ± 1.468
3.681GluPro: 3.681 ± 3.147
3.681GluGln: 3.681 ± 0.419
6.135GluArg: 6.135 ± 1.679
3.681GluSer: 3.681 ± 1.364
6.135GluThr: 6.135 ± 0.104
6.135GluVal: 6.135 ± 0.104
3.681GluTrp: 3.681 ± 1.364
4.908GluTyr: 4.908 ± 1.153
0.0GluXaa: 0.0 ± 0.0
Phe
1.227PheAla: 1.227 ± 0.734
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
1.227PheGlu: 1.227 ± 0.734
0.0PhePhe: 0.0 ± 0.0
1.227PheGly: 1.227 ± 0.734
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.227PheLys: 1.227 ± 0.734
4.908PheLeu: 4.908 ± 0.63
1.227PheMet: 1.227 ± 1.049
3.681PheAsn: 3.681 ± 0.419
0.0PhePro: 0.0 ± 0.0
1.227PheGln: 1.227 ± 0.734
0.0PheArg: 0.0 ± 0.0
1.227PheSer: 1.227 ± 1.049
3.681PheThr: 3.681 ± 1.364
3.681PheVal: 3.681 ± 2.202
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.227GlyAla: 1.227 ± 0.734
1.227GlyCys: 1.227 ± 0.734
2.454GlyAsp: 2.454 ± 1.468
0.0GlyGlu: 0.0 ± 0.0
1.227GlyPhe: 1.227 ± 1.049
2.454GlyGly: 2.454 ± 0.315
4.908GlyHis: 4.908 ± 0.63
3.681GlyIle: 3.681 ± 2.202
6.135GlyLys: 6.135 ± 3.67
4.908GlyLeu: 4.908 ± 1.153
2.454GlyMet: 2.454 ± 1.183
4.908GlyAsn: 4.908 ± 0.63
2.454GlyPro: 2.454 ± 2.098
1.227GlyGln: 1.227 ± 1.049
7.362GlyArg: 7.362 ± 0.945
3.681GlySer: 3.681 ± 1.364
1.227GlyThr: 1.227 ± 0.734
2.454GlyVal: 2.454 ± 0.315
4.908GlyTrp: 4.908 ± 0.63
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.454HisAla: 2.454 ± 0.315
1.227HisCys: 1.227 ± 0.734
0.0HisAsp: 0.0 ± 0.0
6.135HisGlu: 6.135 ± 1.679
0.0HisPhe: 0.0 ± 0.0
2.454HisGly: 2.454 ± 1.468
0.0HisHis: 0.0 ± 0.0
3.681HisIle: 3.681 ± 3.147
0.0HisLys: 0.0 ± 0.0
1.227HisLeu: 1.227 ± 1.049
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.227HisPro: 1.227 ± 1.049
0.0HisGln: 0.0 ± 0.0
2.454HisArg: 2.454 ± 1.468
2.454HisSer: 2.454 ± 0.315
3.681HisThr: 3.681 ± 0.419
1.227HisVal: 1.227 ± 1.049
2.454HisTrp: 2.454 ± 1.468
2.454HisTyr: 2.454 ± 1.468
0.0HisXaa: 0.0 ± 0.0
Ile
7.362IleAla: 7.362 ± 2.728
0.0IleCys: 0.0 ± 0.0
3.681IleAsp: 3.681 ± 1.364
2.454IleGlu: 2.454 ± 1.468
0.0IlePhe: 0.0 ± 0.0
2.454IleGly: 2.454 ± 2.098
1.227IleHis: 1.227 ± 1.049
3.681IleIle: 3.681 ± 1.364
4.908IleLys: 4.908 ± 2.936
1.227IleLeu: 1.227 ± 0.734
2.454IleMet: 2.454 ± 2.098
1.227IleAsn: 1.227 ± 1.049
3.681IlePro: 3.681 ± 0.419
3.681IleGln: 3.681 ± 0.419
1.227IleArg: 1.227 ± 0.734
2.454IleSer: 2.454 ± 0.315
2.454IleThr: 2.454 ± 0.315
2.454IleVal: 2.454 ± 1.468
0.0IleTrp: 0.0 ± 0.0
2.454IleTyr: 2.454 ± 1.468
0.0IleXaa: 0.0 ± 0.0
Lys
1.227LysAla: 1.227 ± 0.734
6.135LysCys: 6.135 ± 1.887
4.908LysAsp: 4.908 ± 1.153
3.681LysGlu: 3.681 ± 2.202
3.681LysPhe: 3.681 ± 0.419
3.681LysGly: 3.681 ± 0.419
1.227LysHis: 1.227 ± 0.734
0.0LysIle: 0.0 ± 0.0
3.681LysLys: 3.681 ± 0.419
6.135LysLeu: 6.135 ± 3.67
0.0LysMet: 0.0 ± 0.0
2.454LysAsn: 2.454 ± 1.468
1.227LysPro: 1.227 ± 1.049
1.227LysGln: 1.227 ± 1.049
4.908LysArg: 4.908 ± 2.936
1.227LysSer: 1.227 ± 0.734
4.908LysThr: 4.908 ± 0.63
4.908LysVal: 4.908 ± 1.153
1.227LysTrp: 1.227 ± 0.734
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.362LeuAla: 7.362 ± 0.838
0.0LeuCys: 0.0 ± 0.0
3.681LeuAsp: 3.681 ± 2.202
8.589LeuGlu: 8.589 ± 1.572
2.454LeuPhe: 2.454 ± 2.098
6.135LeuGly: 6.135 ± 3.67
0.0LeuHis: 0.0 ± 0.0
3.681LeuIle: 3.681 ± 1.364
6.135LeuLys: 6.135 ± 1.887
13.497LeuLeu: 13.497 ± 4.508
1.227LeuMet: 1.227 ± 0.734
2.454LeuAsn: 2.454 ± 0.315
3.681LeuPro: 3.681 ± 2.202
2.454LeuGln: 2.454 ± 1.468
6.135LeuArg: 6.135 ± 1.887
4.908LeuSer: 4.908 ± 2.936
4.908LeuThr: 4.908 ± 1.153
6.135LeuVal: 6.135 ± 0.104
0.0LeuTrp: 0.0 ± 0.0
4.908LeuTyr: 4.908 ± 2.413
0.0LeuXaa: 0.0 ± 0.0
Met
1.227MetAla: 1.227 ± 1.049
0.0MetCys: 0.0 ± 0.0
1.227MetAsp: 1.227 ± 0.734
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.454MetGly: 2.454 ± 0.315
1.227MetHis: 1.227 ± 0.734
1.227MetIle: 1.227 ± 0.734
0.0MetLys: 0.0 ± 0.0
1.227MetLeu: 1.227 ± 1.049
0.0MetMet: 0.0 ± 0.0
2.454MetAsn: 2.454 ± 0.315
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.454MetArg: 2.454 ± 0.315
1.227MetSer: 1.227 ± 0.734
3.681MetThr: 3.681 ± 1.364
1.227MetVal: 1.227 ± 1.049
1.227MetTrp: 1.227 ± 0.734
1.227MetTyr: 1.227 ± 0.734
0.0MetXaa: 0.0 ± 0.0
Asn
2.454AsnAla: 2.454 ± 0.315
2.454AsnCys: 2.454 ± 1.468
2.454AsnAsp: 2.454 ± 0.315
3.681AsnGlu: 3.681 ± 0.419
0.0AsnPhe: 0.0 ± 0.0
3.681AsnGly: 3.681 ± 2.202
1.227AsnHis: 1.227 ± 1.049
1.227AsnIle: 1.227 ± 1.049
3.681AsnLys: 3.681 ± 0.419
2.454AsnLeu: 2.454 ± 1.468
1.227AsnMet: 1.227 ± 1.049
1.227AsnAsn: 1.227 ± 1.049
6.135AsnPro: 6.135 ± 1.887
1.227AsnGln: 1.227 ± 1.049
3.681AsnArg: 3.681 ± 1.364
4.908AsnSer: 4.908 ± 2.413
1.227AsnThr: 1.227 ± 0.734
1.227AsnVal: 1.227 ± 1.049
1.227AsnTrp: 1.227 ± 0.734
1.227AsnTyr: 1.227 ± 0.734
0.0AsnXaa: 0.0 ± 0.0
Pro
4.908ProAla: 4.908 ± 0.63
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
2.454ProGlu: 2.454 ± 0.315
1.227ProPhe: 1.227 ± 0.734
4.908ProGly: 4.908 ± 1.153
1.227ProHis: 1.227 ± 1.049
4.908ProIle: 4.908 ± 0.63
1.227ProLys: 1.227 ± 1.049
2.454ProLeu: 2.454 ± 2.098
0.0ProMet: 0.0 ± 0.0
2.454ProAsn: 2.454 ± 1.468
3.681ProPro: 3.681 ± 3.147
2.454ProGln: 2.454 ± 2.098
2.454ProArg: 2.454 ± 0.315
2.454ProSer: 2.454 ± 0.315
8.589ProThr: 8.589 ± 3.777
7.362ProVal: 7.362 ± 2.621
0.0ProTrp: 0.0 ± 0.0
3.681ProTyr: 3.681 ± 3.147
0.0ProXaa: 0.0 ± 0.0
Gln
3.681GlnAla: 3.681 ± 1.364
1.227GlnCys: 1.227 ± 1.049
0.0GlnAsp: 0.0 ± 0.0
2.454GlnGlu: 2.454 ± 1.468
1.227GlnPhe: 1.227 ± 0.734
1.227GlnGly: 1.227 ± 0.734
3.681GlnHis: 3.681 ± 0.419
0.0GlnIle: 0.0 ± 0.0
1.227GlnLys: 1.227 ± 0.734
2.454GlnLeu: 2.454 ± 1.468
1.227GlnMet: 1.227 ± 1.049
1.227GlnAsn: 1.227 ± 1.049
2.454GlnPro: 2.454 ± 2.098
3.681GlnGln: 3.681 ± 2.202
6.135GlnArg: 6.135 ± 3.462
1.227GlnSer: 1.227 ± 1.049
0.0GlnThr: 0.0 ± 0.0
2.454GlnVal: 2.454 ± 0.315
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
12.27ArgAla: 12.27 ± 1.575
2.454ArgCys: 2.454 ± 2.098
2.454ArgAsp: 2.454 ± 0.315
1.227ArgGlu: 1.227 ± 1.049
1.227ArgPhe: 1.227 ± 0.734
6.135ArgGly: 6.135 ± 1.679
1.227ArgHis: 1.227 ± 1.049
2.454ArgIle: 2.454 ± 1.468
3.681ArgLys: 3.681 ± 2.202
7.362ArgLeu: 7.362 ± 4.404
2.454ArgMet: 2.454 ± 1.045
3.681ArgAsn: 3.681 ± 0.419
6.135ArgPro: 6.135 ± 0.104
0.0ArgGln: 0.0 ± 0.0
6.135ArgArg: 6.135 ± 3.462
3.681ArgSer: 3.681 ± 1.364
3.681ArgThr: 3.681 ± 3.147
1.227ArgVal: 1.227 ± 0.734
2.454ArgTrp: 2.454 ± 1.468
3.681ArgTyr: 3.681 ± 2.202
0.0ArgXaa: 0.0 ± 0.0
Ser
3.681SerAla: 3.681 ± 3.147
1.227SerCys: 1.227 ± 1.049
2.454SerAsp: 2.454 ± 2.098
3.681SerGlu: 3.681 ± 0.419
3.681SerPhe: 3.681 ± 1.364
3.681SerGly: 3.681 ± 1.364
2.454SerHis: 2.454 ± 2.098
7.362SerIle: 7.362 ± 0.945
3.681SerLys: 3.681 ± 0.419
7.362SerLeu: 7.362 ± 0.838
2.454SerMet: 2.454 ± 0.315
2.454SerAsn: 2.454 ± 0.315
0.0SerPro: 0.0 ± 0.0
0.0SerGln: 0.0 ± 0.0
2.454SerArg: 2.454 ± 0.315
3.681SerSer: 3.681 ± 0.419
2.454SerThr: 2.454 ± 0.315
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
1.227SerTyr: 1.227 ± 0.734
0.0SerXaa: 0.0 ± 0.0
Thr
4.908ThrAla: 4.908 ± 0.63
2.454ThrCys: 2.454 ± 0.315
2.454ThrAsp: 2.454 ± 1.468
6.135ThrGlu: 6.135 ± 1.887
0.0ThrPhe: 0.0 ± 0.0
3.681ThrGly: 3.681 ± 0.419
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
6.135ThrLys: 6.135 ± 1.679
4.908ThrLeu: 4.908 ± 1.153
2.454ThrMet: 2.454 ± 0.315
2.454ThrAsn: 2.454 ± 0.315
7.362ThrPro: 7.362 ± 2.728
2.454ThrGln: 2.454 ± 2.098
2.454ThrArg: 2.454 ± 1.468
3.681ThrSer: 3.681 ± 3.147
6.135ThrThr: 6.135 ± 3.67
6.135ThrVal: 6.135 ± 1.679
1.227ThrTrp: 1.227 ± 1.049
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.908ValAla: 4.908 ± 2.413
1.227ValCys: 1.227 ± 1.049
4.908ValAsp: 4.908 ± 0.63
6.135ValGlu: 6.135 ± 0.104
1.227ValPhe: 1.227 ± 1.049
6.135ValGly: 6.135 ± 0.104
3.681ValHis: 3.681 ± 0.419
4.908ValIle: 4.908 ± 0.63
3.681ValLys: 3.681 ± 0.419
8.589ValLeu: 8.589 ± 1.572
0.0ValMet: 0.0 ± 0.0
2.454ValAsn: 2.454 ± 1.468
4.908ValPro: 4.908 ± 1.153
2.454ValGln: 2.454 ± 0.315
3.681ValArg: 3.681 ± 0.419
2.454ValSer: 2.454 ± 2.098
1.227ValThr: 1.227 ± 1.049
4.908ValVal: 4.908 ± 1.153
0.0ValTrp: 0.0 ± 0.0
1.227ValTyr: 1.227 ± 0.734
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.227TrpCys: 1.227 ± 0.734
1.227TrpAsp: 1.227 ± 0.734
1.227TrpGlu: 1.227 ± 0.734
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.227TrpIle: 1.227 ± 0.734
2.454TrpLys: 2.454 ± 1.468
3.681TrpLeu: 3.681 ± 1.364
1.227TrpMet: 1.227 ± 0.734
1.227TrpAsn: 1.227 ± 0.734
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.681TrpArg: 3.681 ± 1.364
1.227TrpSer: 1.227 ± 1.049
1.227TrpThr: 1.227 ± 1.049
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.227TrpTyr: 1.227 ± 1.049
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.454TyrAla: 2.454 ± 0.315
1.227TyrCys: 1.227 ± 0.734
1.227TyrAsp: 1.227 ± 0.734
1.227TyrGlu: 1.227 ± 0.734
1.227TyrPhe: 1.227 ± 0.734
0.0TyrGly: 0.0 ± 0.0
1.227TyrHis: 1.227 ± 0.734
1.227TyrIle: 1.227 ± 1.049
1.227TyrLys: 1.227 ± 0.734
3.681TyrLeu: 3.681 ± 0.419
0.0TyrMet: 0.0 ± 0.0
4.908TyrAsn: 4.908 ± 1.153
2.454TyrPro: 2.454 ± 0.315
2.454TyrGln: 2.454 ± 2.098
4.908TyrArg: 4.908 ± 0.63
2.454TyrSer: 2.454 ± 0.315
2.454TyrThr: 2.454 ± 1.468
2.454TyrVal: 2.454 ± 1.468
0.0TyrTrp: 0.0 ± 0.0
1.227TyrTyr: 1.227 ± 0.734
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (816 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski