Amino acid dipepetide frequency for Mycoplasma bovigenitalium 51080

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.326AlaAla: 3.326 ± 0.151
0.33AlaCys: 0.33 ± 0.034
2.463AlaAsp: 2.463 ± 0.115
3.016AlaGlu: 3.016 ± 0.123
2.566AlaPhe: 2.566 ± 0.116
2.558AlaGly: 2.558 ± 0.125
1.034AlaHis: 1.034 ± 0.063
5.442AlaIle: 5.442 ± 0.185
6.294AlaLys: 6.294 ± 0.236
5.43AlaLeu: 5.43 ± 0.192
1.265AlaMet: 1.265 ± 0.071
4.233AlaAsn: 4.233 ± 0.164
1.329AlaPro: 1.329 ± 0.074
2.288AlaGln: 2.288 ± 0.128
2.16AlaArg: 2.16 ± 0.099
3.576AlaSer: 3.576 ± 0.132
3.031AlaThr: 3.031 ± 0.135
2.705AlaVal: 2.705 ± 0.102
0.398AlaTrp: 0.398 ± 0.041
1.862AlaTyr: 1.862 ± 0.081
0.0AlaXaa: 0.0 ± 0.0
Cys
0.37CysAla: 0.37 ± 0.041
0.04CysCys: 0.04 ± 0.011
0.322CysAsp: 0.322 ± 0.036
0.378CysGlu: 0.378 ± 0.042
0.31CysPhe: 0.31 ± 0.038
0.33CysGly: 0.33 ± 0.039
0.103CysHis: 0.103 ± 0.021
0.418CysIle: 0.418 ± 0.043
0.354CysLys: 0.354 ± 0.039
0.541CysLeu: 0.541 ± 0.057
0.111CysMet: 0.111 ± 0.02
0.33CysAsn: 0.33 ± 0.037
0.187CysPro: 0.187 ± 0.026
0.215CysGln: 0.215 ± 0.027
0.155CysArg: 0.155 ± 0.027
0.418CysSer: 0.418 ± 0.048
0.267CysThr: 0.267 ± 0.036
0.338CysVal: 0.338 ± 0.034
0.056CysTrp: 0.056 ± 0.014
0.263CysTyr: 0.263 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
3.087AspAla: 3.087 ± 0.128
0.239AspCys: 0.239 ± 0.033
2.665AspAsp: 2.665 ± 0.125
4.547AspGlu: 4.547 ± 0.155
3.676AspPhe: 3.676 ± 0.109
2.494AspGly: 2.494 ± 0.124
0.772AspHis: 0.772 ± 0.052
4.953AspIle: 4.953 ± 0.148
6.174AspLys: 6.174 ± 0.184
5.442AspLeu: 5.442 ± 0.167
0.684AspMet: 0.684 ± 0.045
3.875AspAsn: 3.875 ± 0.132
1.54AspPro: 1.54 ± 0.077
1.675AspGln: 1.675 ± 0.105
1.373AspArg: 1.373 ± 0.082
3.572AspSer: 3.572 ± 0.121
2.367AspThr: 2.367 ± 0.096
3.183AspVal: 3.183 ± 0.124
0.672AspTrp: 0.672 ± 0.058
2.55AspTyr: 2.55 ± 0.117
0.0AspXaa: 0.0 ± 0.0
Glu
3.254GluAla: 3.254 ± 0.153
0.255GluCys: 0.255 ± 0.033
2.626GluAsp: 2.626 ± 0.096
4.201GluGlu: 4.201 ± 0.195
4.181GluPhe: 4.181 ± 0.142
2.335GluGly: 2.335 ± 0.111
1.158GluHis: 1.158 ± 0.067
6.461GluIle: 6.461 ± 0.182
7.929GluLys: 7.929 ± 0.211
7.785GluLeu: 7.785 ± 0.246
1.333GluMet: 1.333 ± 0.072
5.924GluAsn: 5.924 ± 0.162
1.488GluPro: 1.488 ± 0.093
3.163GluGln: 3.163 ± 0.117
1.886GluArg: 1.886 ± 0.104
3.652GluSer: 3.652 ± 0.131
3.127GluThr: 3.127 ± 0.13
3.409GluVal: 3.409 ± 0.139
0.605GluTrp: 0.605 ± 0.051
3.02GluTyr: 3.02 ± 0.108
0.0GluXaa: 0.0 ± 0.0
Phe
3.302PheAla: 3.302 ± 0.16
0.294PheCys: 0.294 ± 0.035
3.752PheAsp: 3.752 ± 0.129
3.628PheGlu: 3.628 ± 0.128
2.256PhePhe: 2.256 ± 0.118
2.626PheGly: 2.626 ± 0.106
0.553PheHis: 0.553 ± 0.049
5.438PheIle: 5.438 ± 0.179
5.323PheLys: 5.323 ± 0.16
4.277PheLeu: 4.277 ± 0.163
0.967PheMet: 0.967 ± 0.059
4.456PheAsn: 4.456 ± 0.164
1.074PhePro: 1.074 ± 0.068
1.146PheGln: 1.146 ± 0.068
1.373PheArg: 1.373 ± 0.074
3.779PheSer: 3.779 ± 0.159
2.606PheThr: 2.606 ± 0.111
3.195PheVal: 3.195 ± 0.124
0.505PheTrp: 0.505 ± 0.046
2.049PheTyr: 2.049 ± 0.105
0.0PheXaa: 0.0 ± 0.0
Gly
2.693GlyAla: 2.693 ± 0.129
0.247GlyCys: 0.247 ± 0.029
2.57GlyAsp: 2.57 ± 0.109
2.697GlyGlu: 2.697 ± 0.12
2.697GlyPhe: 2.697 ± 0.12
2.868GlyGly: 2.868 ± 0.132
0.923GlyHis: 0.923 ± 0.064
4.384GlyIle: 4.384 ± 0.142
4.432GlyLys: 4.432 ± 0.174
4.074GlyLeu: 4.074 ± 0.149
0.899GlyMet: 0.899 ± 0.075
2.582GlyAsn: 2.582 ± 0.11
0.899GlyPro: 0.899 ± 0.072
1.798GlyGln: 1.798 ± 0.088
1.492GlyArg: 1.492 ± 0.103
3.039GlySer: 3.039 ± 0.129
2.443GlyThr: 2.443 ± 0.116
3.059GlyVal: 3.059 ± 0.111
0.485GlyTrp: 0.485 ± 0.046
2.144GlyTyr: 2.144 ± 0.081
0.0GlyXaa: 0.0 ± 0.0
His
0.879HisAla: 0.879 ± 0.063
0.111HisCys: 0.111 ± 0.027
0.772HisAsp: 0.772 ± 0.052
0.971HisGlu: 0.971 ± 0.058
0.963HisPhe: 0.963 ± 0.059
0.947HisGly: 0.947 ± 0.071
0.33HisHis: 0.33 ± 0.036
1.496HisIle: 1.496 ± 0.07
1.536HisLys: 1.536 ± 0.076
1.416HisLeu: 1.416 ± 0.074
0.227HisMet: 0.227 ± 0.028
1.289HisAsn: 1.289 ± 0.07
0.597HisPro: 0.597 ± 0.055
0.565HisGln: 0.565 ± 0.054
0.573HisArg: 0.573 ± 0.062
1.054HisSer: 1.054 ± 0.077
0.748HisThr: 0.748 ± 0.057
0.692HisVal: 0.692 ± 0.061
0.127HisTrp: 0.127 ± 0.024
0.625HisTyr: 0.625 ± 0.047
0.0HisXaa: 0.0 ± 0.0
Ile
5.339IleAla: 5.339 ± 0.164
0.692IleCys: 0.692 ± 0.063
6.612IleAsp: 6.612 ± 0.182
7.583IleGlu: 7.583 ± 0.183
4.758IlePhe: 4.758 ± 0.204
4.368IleGly: 4.368 ± 0.161
1.293IleHis: 1.293 ± 0.067
8.438IleIle: 8.438 ± 0.268
9.576IleLys: 9.576 ± 0.209
7.515IleLeu: 7.515 ± 0.196
1.468IleMet: 1.468 ± 0.083
8.048IleAsn: 8.048 ± 0.23
2.518IlePro: 2.518 ± 0.119
2.813IleGln: 2.813 ± 0.1
2.61IleArg: 2.61 ± 0.107
6.91IleSer: 6.91 ± 0.176
4.758IleThr: 4.758 ± 0.124
5.231IleVal: 5.231 ± 0.18
0.784IleTrp: 0.784 ± 0.058
3.505IleTyr: 3.505 ± 0.128
0.0IleXaa: 0.0 ± 0.0
Lys
5.009LysAla: 5.009 ± 0.188
0.422LysCys: 0.422 ± 0.045
5.971LysAsp: 5.971 ± 0.195
7.181LysGlu: 7.181 ± 0.236
4.865LysPhe: 4.865 ± 0.144
3.815LysGly: 3.815 ± 0.143
1.834LysHis: 1.834 ± 0.08
10.129LysIle: 10.129 ± 0.216
8.768LysLys: 8.768 ± 0.241
9.452LysLeu: 9.452 ± 0.228
2.371LysMet: 2.371 ± 0.102
9.56LysAsn: 9.56 ± 0.246
2.725LysPro: 2.725 ± 0.108
4.623LysGln: 4.623 ± 0.19
2.936LysArg: 2.936 ± 0.109
6.302LysSer: 6.302 ± 0.169
5.721LysThr: 5.721 ± 0.142
4.897LysVal: 4.897 ± 0.151
1.038LysTrp: 1.038 ± 0.067
5.243LysTyr: 5.243 ± 0.168
0.0LysXaa: 0.0 ± 0.0
Leu
5.761LeuAla: 5.761 ± 0.173
0.597LeuCys: 0.597 ± 0.055
5.391LeuAsp: 5.391 ± 0.149
5.816LeuGlu: 5.816 ± 0.179
4.667LeuPhe: 4.667 ± 0.186
4.253LeuGly: 4.253 ± 0.149
1.452LeuHis: 1.452 ± 0.076
8.824LeuIle: 8.824 ± 0.238
9.051LeuLys: 9.051 ± 0.226
7.941LeuLeu: 7.941 ± 0.231
1.532LeuMet: 1.532 ± 0.079
7.296LeuAsn: 7.296 ± 0.253
2.709LeuPro: 2.709 ± 0.115
2.737LeuGln: 2.737 ± 0.125
2.829LeuArg: 2.829 ± 0.109
6.588LeuSer: 6.588 ± 0.171
4.909LeuThr: 4.909 ± 0.156
5.263LeuVal: 5.263 ± 0.17
0.736LeuTrp: 0.736 ± 0.059
2.984LeuTyr: 2.984 ± 0.108
0.0LeuXaa: 0.0 ± 0.0
Met
1.054MetAla: 1.054 ± 0.067
0.123MetCys: 0.123 ± 0.02
0.859MetAsp: 0.859 ± 0.069
0.716MetGlu: 0.716 ± 0.059
1.074MetPhe: 1.074 ± 0.057
0.776MetGly: 0.776 ± 0.058
0.318MetHis: 0.318 ± 0.033
1.488MetIle: 1.488 ± 0.093
1.754MetLys: 1.754 ± 0.079
1.834MetLeu: 1.834 ± 0.101
0.406MetMet: 0.406 ± 0.038
1.428MetAsn: 1.428 ± 0.081
0.776MetPro: 0.776 ± 0.058
0.76MetGln: 0.76 ± 0.054
0.644MetArg: 0.644 ± 0.059
1.424MetSer: 1.424 ± 0.078
0.74MetThr: 0.74 ± 0.061
0.979MetVal: 0.979 ± 0.066
0.151MetTrp: 0.151 ± 0.024
0.537MetTyr: 0.537 ± 0.038
0.0MetXaa: 0.0 ± 0.0
Asn
3.927AsnAla: 3.927 ± 0.145
0.33AsnCys: 0.33 ± 0.036
4.456AsnAsp: 4.456 ± 0.18
6.111AsnGlu: 6.111 ± 0.235
3.891AsnPhe: 3.891 ± 0.155
3.545AsnGly: 3.545 ± 0.123
1.018AsnHis: 1.018 ± 0.065
7.738AsnIle: 7.738 ± 0.205
9.066AsnLys: 9.066 ± 0.257
6.795AsnLeu: 6.795 ± 0.215
1.17AsnMet: 1.17 ± 0.086
6.894AsnAsn: 6.894 ± 0.257
2.478AsnPro: 2.478 ± 0.118
2.96AsnGln: 2.96 ± 0.128
2.069AsnArg: 2.069 ± 0.086
5.689AsnSer: 5.689 ± 0.197
3.461AsnThr: 3.461 ± 0.118
4.118AsnVal: 4.118 ± 0.157
0.827AsnTrp: 0.827 ± 0.059
3.214AsnTyr: 3.214 ± 0.128
0.0AsnXaa: 0.0 ± 0.0
Pro
1.213ProAla: 1.213 ± 0.072
0.131ProCys: 0.131 ± 0.021
1.384ProAsp: 1.384 ± 0.073
2.164ProGlu: 2.164 ± 0.1
1.333ProPhe: 1.333 ± 0.075
1.273ProGly: 1.273 ± 0.076
0.509ProHis: 0.509 ± 0.041
2.602ProIle: 2.602 ± 0.104
2.574ProLys: 2.574 ± 0.117
2.232ProLeu: 2.232 ± 0.097
0.438ProMet: 0.438 ± 0.041
2.16ProAsn: 2.16 ± 0.124
0.489ProPro: 0.489 ± 0.05
0.931ProGln: 0.931 ± 0.057
0.66ProArg: 0.66 ± 0.049
1.754ProSer: 1.754 ± 0.08
1.806ProThr: 1.806 ± 0.089
1.544ProVal: 1.544 ± 0.082
0.286ProTrp: 0.286 ± 0.036
1.074ProTyr: 1.074 ± 0.062
0.0ProXaa: 0.0 ± 0.0
Gln
2.017GlnAla: 2.017 ± 0.088
0.135GlnCys: 0.135 ± 0.025
1.727GlnAsp: 1.727 ± 0.094
2.26GlnGlu: 2.26 ± 0.117
1.631GlnPhe: 1.631 ± 0.085
1.392GlnGly: 1.392 ± 0.079
0.581GlnHis: 0.581 ± 0.05
3.847GlnIle: 3.847 ± 0.135
4.181GlnLys: 4.181 ± 0.17
3.099GlnLeu: 3.099 ± 0.122
0.744GlnMet: 0.744 ± 0.058
3.33GlnAsn: 3.33 ± 0.123
0.883GlnPro: 0.883 ± 0.051
1.376GlnGln: 1.376 ± 0.094
1.193GlnArg: 1.193 ± 0.062
2.073GlnSer: 2.073 ± 0.09
1.922GlnThr: 1.922 ± 0.096
1.814GlnVal: 1.814 ± 0.085
0.314GlnTrp: 0.314 ± 0.033
1.492GlnTyr: 1.492 ± 0.082
0.0GlnXaa: 0.0 ± 0.0
Arg
1.683ArgAla: 1.683 ± 0.101
0.127ArgCys: 0.127 ± 0.022
1.655ArgAsp: 1.655 ± 0.096
2.18ArgGlu: 2.18 ± 0.103
1.591ArgPhe: 1.591 ± 0.075
1.432ArgGly: 1.432 ± 0.089
0.513ArgHis: 0.513 ± 0.041
2.681ArgIle: 2.681 ± 0.117
3.039ArgLys: 3.039 ± 0.122
2.713ArgLeu: 2.713 ± 0.099
0.7ArgMet: 0.7 ± 0.057
2.101ArgAsn: 2.101 ± 0.087
0.839ArgPro: 0.839 ± 0.072
1.086ArgGln: 1.086 ± 0.064
1.162ArgArg: 1.162 ± 0.077
1.647ArgSer: 1.647 ± 0.077
1.424ArgThr: 1.424 ± 0.081
1.81ArgVal: 1.81 ± 0.088
0.29ArgTrp: 0.29 ± 0.037
1.205ArgTyr: 1.205 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
3.421SerAla: 3.421 ± 0.128
0.501SerCys: 0.501 ± 0.051
3.584SerAsp: 3.584 ± 0.13
4.193SerGlu: 4.193 ± 0.133
3.692SerPhe: 3.692 ± 0.134
3.565SerGly: 3.565 ± 0.109
0.967SerHis: 0.967 ± 0.062
6.687SerIle: 6.687 ± 0.164
6.986SerLys: 6.986 ± 0.168
6.584SerLeu: 6.584 ± 0.176
1.062SerMet: 1.062 ± 0.062
4.794SerAsn: 4.794 ± 0.179
1.619SerPro: 1.619 ± 0.089
2.542SerGln: 2.542 ± 0.1
2.029SerArg: 2.029 ± 0.073
4.901SerSer: 4.901 ± 0.16
3.421SerThr: 3.421 ± 0.114
3.489SerVal: 3.489 ± 0.113
0.625SerTrp: 0.625 ± 0.053
2.542SerTyr: 2.542 ± 0.106
0.0SerXaa: 0.0 ± 0.0
Thr
2.411ThrAla: 2.411 ± 0.086
0.255ThrCys: 0.255 ± 0.036
2.431ThrAsp: 2.431 ± 0.118
2.928ThrGlu: 2.928 ± 0.13
2.57ThrPhe: 2.57 ± 0.105
2.53ThrGly: 2.53 ± 0.116
0.959ThrHis: 0.959 ± 0.064
4.782ThrIle: 4.782 ± 0.133
5.327ThrLys: 5.327 ± 0.156
4.778ThrLeu: 4.778 ± 0.14
0.788ThrMet: 0.788 ± 0.057
4.058ThrAsn: 4.058 ± 0.129
1.723ThrPro: 1.723 ± 0.078
1.914ThrGln: 1.914 ± 0.087
1.587ThrArg: 1.587 ± 0.098
3.37ThrSer: 3.37 ± 0.13
2.94ThrThr: 2.94 ± 0.119
2.602ThrVal: 2.602 ± 0.105
0.43ThrTrp: 0.43 ± 0.041
1.894ThrTyr: 1.894 ± 0.106
0.0ThrXaa: 0.0 ± 0.0
Val
3.871ValAla: 3.871 ± 0.125
0.382ValCys: 0.382 ± 0.046
3.417ValAsp: 3.417 ± 0.119
3.867ValGlu: 3.867 ± 0.13
2.864ValPhe: 2.864 ± 0.121
2.825ValGly: 2.825 ± 0.131
0.8ValHis: 0.8 ± 0.064
4.846ValIle: 4.846 ± 0.144
5.522ValLys: 5.522 ± 0.159
4.698ValLeu: 4.698 ± 0.144
0.871ValMet: 0.871 ± 0.065
3.708ValAsn: 3.708 ± 0.147
1.313ValPro: 1.313 ± 0.083
1.643ValGln: 1.643 ± 0.072
1.528ValArg: 1.528 ± 0.081
3.863ValSer: 3.863 ± 0.143
2.319ValThr: 2.319 ± 0.096
3.457ValVal: 3.457 ± 0.146
0.521ValTrp: 0.521 ± 0.045
2.093ValTyr: 2.093 ± 0.102
0.0ValXaa: 0.0 ± 0.0
Trp
0.438TrpAla: 0.438 ± 0.039
0.052TrpCys: 0.052 ± 0.016
0.505TrpAsp: 0.505 ± 0.048
0.617TrpGlu: 0.617 ± 0.054
0.641TrpPhe: 0.641 ± 0.054
0.454TrpGly: 0.454 ± 0.044
0.151TrpHis: 0.151 ± 0.025
0.939TrpIle: 0.939 ± 0.065
0.831TrpLys: 0.831 ± 0.057
0.827TrpLeu: 0.827 ± 0.058
0.211TrpMet: 0.211 ± 0.029
0.712TrpAsn: 0.712 ± 0.052
0.243TrpPro: 0.243 ± 0.03
0.342TrpGln: 0.342 ± 0.037
0.294TrpArg: 0.294 ± 0.031
0.605TrpSer: 0.605 ± 0.05
0.481TrpThr: 0.481 ± 0.049
0.597TrpVal: 0.597 ± 0.052
0.143TrpTrp: 0.143 ± 0.027
0.469TrpTyr: 0.469 ± 0.046
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.252TyrAla: 2.252 ± 0.103
0.243TyrCys: 0.243 ± 0.027
2.379TyrAsp: 2.379 ± 0.104
2.737TyrGlu: 2.737 ± 0.116
2.371TyrPhe: 2.371 ± 0.113
2.041TyrGly: 2.041 ± 0.101
0.648TyrHis: 0.648 ± 0.057
3.226TyrIle: 3.226 ± 0.124
4.145TyrLys: 4.145 ± 0.137
3.899TyrLeu: 3.899 ± 0.148
0.593TyrMet: 0.593 ± 0.051
2.98TyrAsn: 2.98 ± 0.135
1.13TyrPro: 1.13 ± 0.075
1.436TyrGln: 1.436 ± 0.069
1.329TyrArg: 1.329 ± 0.079
2.988TyrSer: 2.988 ± 0.108
1.782TyrThr: 1.782 ± 0.076
2.029TyrVal: 2.029 ± 0.096
0.557TyrTrp: 0.557 ± 0.045
1.651TyrTyr: 1.651 ± 0.103
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 677 proteins (251366 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski