Amino acid dipepetide frequency for Wenzhou picorna-like virus 45

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.02AlaAla: 8.02 ± 0.0
1.395AlaCys: 1.395 ± 0.0
3.487AlaAsp: 3.487 ± 0.0
2.789AlaGlu: 2.789 ± 0.0
3.835AlaPhe: 3.835 ± 0.0
5.927AlaGly: 5.927 ± 0.0
2.092AlaHis: 2.092 ± 0.0
2.092AlaIle: 2.092 ± 0.0
3.835AlaLys: 3.835 ± 0.0
5.927AlaLeu: 5.927 ± 0.0
1.743AlaMet: 1.743 ± 0.0
4.184AlaAsn: 4.184 ± 0.0
6.625AlaPro: 6.625 ± 0.0
2.092AlaGln: 2.092 ± 0.0
4.184AlaArg: 4.184 ± 0.0
4.881AlaSer: 4.881 ± 0.0
4.881AlaThr: 4.881 ± 0.0
5.23AlaVal: 5.23 ± 0.0
0.697AlaTrp: 0.697 ± 0.0
1.743AlaTyr: 1.743 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.743CysAla: 1.743 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.395CysAsp: 1.395 ± 0.0
0.697CysGlu: 0.697 ± 0.0
0.349CysPhe: 0.349 ± 0.0
3.487CysGly: 3.487 ± 0.0
0.349CysHis: 0.349 ± 0.0
1.743CysIle: 1.743 ± 0.0
0.697CysLys: 0.697 ± 0.0
1.743CysLeu: 1.743 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.743CysAsn: 1.743 ± 0.0
0.697CysPro: 0.697 ± 0.0
0.349CysGln: 0.349 ± 0.0
0.349CysArg: 0.349 ± 0.0
1.046CysSer: 1.046 ± 0.0
1.743CysThr: 1.743 ± 0.0
1.395CysVal: 1.395 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.349CysTyr: 0.349 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.927AspAla: 5.927 ± 0.0
2.092AspCys: 2.092 ± 0.0
5.579AspAsp: 5.579 ± 0.0
6.974AspGlu: 6.974 ± 0.0
2.441AspPhe: 2.441 ± 0.0
4.533AspGly: 4.533 ± 0.0
1.743AspHis: 1.743 ± 0.0
3.138AspIle: 3.138 ± 0.0
1.743AspLys: 1.743 ± 0.0
4.184AspLeu: 4.184 ± 0.0
2.092AspMet: 2.092 ± 0.0
3.487AspAsn: 3.487 ± 0.0
2.441AspPro: 2.441 ± 0.0
1.395AspGln: 1.395 ± 0.0
3.835AspArg: 3.835 ± 0.0
4.881AspSer: 4.881 ± 0.0
2.441AspThr: 2.441 ± 0.0
3.835AspVal: 3.835 ± 0.0
1.395AspTrp: 1.395 ± 0.0
1.743AspTyr: 1.743 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
0.697GluAla: 0.697 ± 0.0
1.743GluCys: 1.743 ± 0.0
1.743GluAsp: 1.743 ± 0.0
4.533GluGlu: 4.533 ± 0.0
2.441GluPhe: 2.441 ± 0.0
2.092GluGly: 2.092 ± 0.0
0.697GluHis: 0.697 ± 0.0
3.138GluIle: 3.138 ± 0.0
3.138GluLys: 3.138 ± 0.0
5.927GluLeu: 5.927 ± 0.0
2.441GluMet: 2.441 ± 0.0
1.395GluAsn: 1.395 ± 0.0
2.441GluPro: 2.441 ± 0.0
2.092GluGln: 2.092 ± 0.0
2.441GluArg: 2.441 ± 0.0
4.533GluSer: 4.533 ± 0.0
2.092GluThr: 2.092 ± 0.0
6.974GluVal: 6.974 ± 0.0
0.0GluTrp: 0.0 ± 0.0
3.138GluTyr: 3.138 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.789PheAla: 2.789 ± 0.0
2.441PheCys: 2.441 ± 0.0
1.743PheAsp: 1.743 ± 0.0
2.789PheGlu: 2.789 ± 0.0
1.046PhePhe: 1.046 ± 0.0
2.789PheGly: 2.789 ± 0.0
0.697PheHis: 0.697 ± 0.0
3.487PheIle: 3.487 ± 0.0
3.487PheLys: 3.487 ± 0.0
4.881PheLeu: 4.881 ± 0.0
0.697PheMet: 0.697 ± 0.0
3.835PheAsn: 3.835 ± 0.0
2.092PhePro: 2.092 ± 0.0
1.395PheGln: 1.395 ± 0.0
3.138PheArg: 3.138 ± 0.0
2.441PheSer: 2.441 ± 0.0
2.441PheThr: 2.441 ± 0.0
3.835PheVal: 3.835 ± 0.0
0.349PheTrp: 0.349 ± 0.0
1.395PheTyr: 1.395 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.835GlyAla: 3.835 ± 0.0
1.046GlyCys: 1.046 ± 0.0
8.02GlyAsp: 8.02 ± 0.0
3.138GlyGlu: 3.138 ± 0.0
3.487GlyPhe: 3.487 ± 0.0
3.487GlyGly: 3.487 ± 0.0
0.697GlyHis: 0.697 ± 0.0
4.881GlyIle: 4.881 ± 0.0
3.138GlyLys: 3.138 ± 0.0
3.487GlyLeu: 3.487 ± 0.0
2.092GlyMet: 2.092 ± 0.0
2.789GlyAsn: 2.789 ± 0.0
2.441GlyPro: 2.441 ± 0.0
1.395GlyGln: 1.395 ± 0.0
2.441GlyArg: 2.441 ± 0.0
4.184GlySer: 4.184 ± 0.0
4.184GlyThr: 4.184 ± 0.0
6.276GlyVal: 6.276 ± 0.0
0.697GlyTrp: 0.697 ± 0.0
2.789GlyTyr: 2.789 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.697HisAla: 0.697 ± 0.0
0.349HisCys: 0.349 ± 0.0
1.395HisAsp: 1.395 ± 0.0
1.395HisGlu: 1.395 ± 0.0
1.046HisPhe: 1.046 ± 0.0
2.441HisGly: 2.441 ± 0.0
0.349HisHis: 0.349 ± 0.0
1.046HisIle: 1.046 ± 0.0
0.697HisLys: 0.697 ± 0.0
1.743HisLeu: 1.743 ± 0.0
1.046HisMet: 1.046 ± 0.0
0.697HisAsn: 0.697 ± 0.0
0.697HisPro: 0.697 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.697HisArg: 0.697 ± 0.0
1.743HisSer: 1.743 ± 0.0
1.395HisThr: 1.395 ± 0.0
1.743HisVal: 1.743 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.441HisTyr: 2.441 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.184IleAla: 4.184 ± 0.0
0.349IleCys: 0.349 ± 0.0
3.138IleAsp: 3.138 ± 0.0
3.138IleGlu: 3.138 ± 0.0
0.697IlePhe: 0.697 ± 0.0
4.533IleGly: 4.533 ± 0.0
1.046IleHis: 1.046 ± 0.0
4.533IleIle: 4.533 ± 0.0
3.835IleLys: 3.835 ± 0.0
5.23IleLeu: 5.23 ± 0.0
2.441IleMet: 2.441 ± 0.0
2.789IleAsn: 2.789 ± 0.0
4.184IlePro: 4.184 ± 0.0
0.349IleGln: 0.349 ± 0.0
2.441IleArg: 2.441 ± 0.0
3.138IleSer: 3.138 ± 0.0
1.743IleThr: 1.743 ± 0.0
4.533IleVal: 4.533 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.395IleTyr: 1.395 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.138LysAla: 3.138 ± 0.0
2.092LysCys: 2.092 ± 0.0
3.487LysAsp: 3.487 ± 0.0
1.743LysGlu: 1.743 ± 0.0
2.092LysPhe: 2.092 ± 0.0
2.789LysGly: 2.789 ± 0.0
1.743LysHis: 1.743 ± 0.0
2.441LysIle: 2.441 ± 0.0
4.881LysLys: 4.881 ± 0.0
5.23LysLeu: 5.23 ± 0.0
0.697LysMet: 0.697 ± 0.0
3.487LysAsn: 3.487 ± 0.0
2.441LysPro: 2.441 ± 0.0
0.697LysGln: 0.697 ± 0.0
2.789LysArg: 2.789 ± 0.0
5.23LysSer: 5.23 ± 0.0
3.138LysThr: 3.138 ± 0.0
1.743LysVal: 1.743 ± 0.0
0.349LysTrp: 0.349 ± 0.0
2.441LysTyr: 2.441 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.23LeuAla: 5.23 ± 0.0
1.046LeuCys: 1.046 ± 0.0
6.625LeuAsp: 6.625 ± 0.0
4.184LeuGlu: 4.184 ± 0.0
3.487LeuPhe: 3.487 ± 0.0
5.927LeuGly: 5.927 ± 0.0
2.092LeuHis: 2.092 ± 0.0
5.23LeuIle: 5.23 ± 0.0
4.184LeuLys: 4.184 ± 0.0
5.579LeuLeu: 5.579 ± 0.0
1.046LeuMet: 1.046 ± 0.0
4.184LeuAsn: 4.184 ± 0.0
4.881LeuPro: 4.881 ± 0.0
2.092LeuGln: 2.092 ± 0.0
4.881LeuArg: 4.881 ± 0.0
5.579LeuSer: 5.579 ± 0.0
5.579LeuThr: 5.579 ± 0.0
5.579LeuVal: 5.579 ± 0.0
1.046LeuTrp: 1.046 ± 0.0
1.395LeuTyr: 1.395 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.789MetAla: 2.789 ± 0.0
0.697MetCys: 0.697 ± 0.0
1.743MetAsp: 1.743 ± 0.0
1.395MetGlu: 1.395 ± 0.0
0.349MetPhe: 0.349 ± 0.0
1.743MetGly: 1.743 ± 0.0
0.697MetHis: 0.697 ± 0.0
0.697MetIle: 0.697 ± 0.0
2.441MetLys: 2.441 ± 0.0
4.533MetLeu: 4.533 ± 0.0
0.697MetMet: 0.697 ± 0.0
1.046MetAsn: 1.046 ± 0.0
1.046MetPro: 1.046 ± 0.0
0.349MetGln: 0.349 ± 0.0
1.395MetArg: 1.395 ± 0.0
2.789MetSer: 2.789 ± 0.0
0.697MetThr: 0.697 ± 0.0
3.835MetVal: 3.835 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.697MetTyr: 0.697 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.092AsnAla: 2.092 ± 0.0
1.395AsnCys: 1.395 ± 0.0
1.395AsnAsp: 1.395 ± 0.0
0.697AsnGlu: 0.697 ± 0.0
2.092AsnPhe: 2.092 ± 0.0
2.441AsnGly: 2.441 ± 0.0
0.349AsnHis: 0.349 ± 0.0
2.092AsnIle: 2.092 ± 0.0
2.092AsnLys: 2.092 ± 0.0
2.789AsnLeu: 2.789 ± 0.0
1.395AsnMet: 1.395 ± 0.0
0.349AsnAsn: 0.349 ± 0.0
3.138AsnPro: 3.138 ± 0.0
0.697AsnGln: 0.697 ± 0.0
2.092AsnArg: 2.092 ± 0.0
3.835AsnSer: 3.835 ± 0.0
4.881AsnThr: 4.881 ± 0.0
5.579AsnVal: 5.579 ± 0.0
0.349AsnTrp: 0.349 ± 0.0
3.487AsnTyr: 3.487 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.487ProAla: 3.487 ± 0.0
0.0ProCys: 0.0 ± 0.0
2.789ProAsp: 2.789 ± 0.0
4.184ProGlu: 4.184 ± 0.0
4.533ProPhe: 4.533 ± 0.0
2.092ProGly: 2.092 ± 0.0
1.046ProHis: 1.046 ± 0.0
2.789ProIle: 2.789 ± 0.0
2.441ProLys: 2.441 ± 0.0
3.138ProLeu: 3.138 ± 0.0
1.743ProMet: 1.743 ± 0.0
2.092ProAsn: 2.092 ± 0.0
3.835ProPro: 3.835 ± 0.0
1.395ProGln: 1.395 ± 0.0
1.046ProArg: 1.046 ± 0.0
4.184ProSer: 4.184 ± 0.0
5.23ProThr: 5.23 ± 0.0
4.533ProVal: 4.533 ± 0.0
1.046ProTrp: 1.046 ± 0.0
2.441ProTyr: 2.441 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.743GlnAla: 1.743 ± 0.0
0.349GlnCys: 0.349 ± 0.0
2.441GlnAsp: 2.441 ± 0.0
0.697GlnGlu: 0.697 ± 0.0
1.395GlnPhe: 1.395 ± 0.0
1.743GlnGly: 1.743 ± 0.0
0.349GlnHis: 0.349 ± 0.0
0.697GlnIle: 0.697 ± 0.0
1.046GlnLys: 1.046 ± 0.0
1.046GlnLeu: 1.046 ± 0.0
1.395GlnMet: 1.395 ± 0.0
1.046GlnAsn: 1.046 ± 0.0
1.395GlnPro: 1.395 ± 0.0
0.697GlnGln: 0.697 ± 0.0
0.697GlnArg: 0.697 ± 0.0
2.441GlnSer: 2.441 ± 0.0
2.092GlnThr: 2.092 ± 0.0
2.092GlnVal: 2.092 ± 0.0
0.697GlnTrp: 0.697 ± 0.0
1.046GlnTyr: 1.046 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.881ArgAla: 4.881 ± 0.0
1.046ArgCys: 1.046 ± 0.0
1.743ArgAsp: 1.743 ± 0.0
2.441ArgGlu: 2.441 ± 0.0
4.533ArgPhe: 4.533 ± 0.0
2.092ArgGly: 2.092 ± 0.0
1.743ArgHis: 1.743 ± 0.0
3.487ArgIle: 3.487 ± 0.0
2.441ArgLys: 2.441 ± 0.0
2.789ArgLeu: 2.789 ± 0.0
0.349ArgMet: 0.349 ± 0.0
1.046ArgAsn: 1.046 ± 0.0
2.441ArgPro: 2.441 ± 0.0
2.092ArgGln: 2.092 ± 0.0
2.441ArgArg: 2.441 ± 0.0
3.487ArgSer: 3.487 ± 0.0
3.138ArgThr: 3.138 ± 0.0
2.789ArgVal: 2.789 ± 0.0
0.697ArgTrp: 0.697 ± 0.0
2.092ArgTyr: 2.092 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.533SerAla: 4.533 ± 0.0
0.349SerCys: 0.349 ± 0.0
4.184SerAsp: 4.184 ± 0.0
4.881SerGlu: 4.881 ± 0.0
3.835SerPhe: 3.835 ± 0.0
6.625SerGly: 6.625 ± 0.0
1.743SerHis: 1.743 ± 0.0
5.23SerIle: 5.23 ± 0.0
3.835SerLys: 3.835 ± 0.0
7.671SerLeu: 7.671 ± 0.0
3.487SerMet: 3.487 ± 0.0
2.441SerAsn: 2.441 ± 0.0
2.441SerPro: 2.441 ± 0.0
2.092SerGln: 2.092 ± 0.0
3.487SerArg: 3.487 ± 0.0
9.066SerSer: 9.066 ± 0.0
4.184SerThr: 4.184 ± 0.0
5.927SerVal: 5.927 ± 0.0
0.0SerTrp: 0.0 ± 0.0
3.138SerTyr: 3.138 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.974ThrAla: 6.974 ± 0.0
0.697ThrCys: 0.697 ± 0.0
4.184ThrAsp: 4.184 ± 0.0
2.789ThrGlu: 2.789 ± 0.0
3.138ThrPhe: 3.138 ± 0.0
2.789ThrGly: 2.789 ± 0.0
1.395ThrHis: 1.395 ± 0.0
1.743ThrIle: 1.743 ± 0.0
1.743ThrLys: 1.743 ± 0.0
3.138ThrLeu: 3.138 ± 0.0
2.441ThrMet: 2.441 ± 0.0
2.441ThrAsn: 2.441 ± 0.0
5.23ThrPro: 5.23 ± 0.0
1.743ThrGln: 1.743 ± 0.0
3.138ThrArg: 3.138 ± 0.0
4.881ThrSer: 4.881 ± 0.0
3.835ThrThr: 3.835 ± 0.0
5.579ThrVal: 5.579 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
2.092ThrTyr: 2.092 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.066ValAla: 9.066 ± 0.0
1.395ValCys: 1.395 ± 0.0
7.322ValAsp: 7.322 ± 0.0
4.533ValGlu: 4.533 ± 0.0
4.184ValPhe: 4.184 ± 0.0
4.184ValGly: 4.184 ± 0.0
1.743ValHis: 1.743 ± 0.0
3.138ValIle: 3.138 ± 0.0
3.835ValLys: 3.835 ± 0.0
5.23ValLeu: 5.23 ± 0.0
2.092ValMet: 2.092 ± 0.0
2.789ValAsn: 2.789 ± 0.0
4.184ValPro: 4.184 ± 0.0
2.789ValGln: 2.789 ± 0.0
3.835ValArg: 3.835 ± 0.0
7.322ValSer: 7.322 ± 0.0
3.835ValThr: 3.835 ± 0.0
6.276ValVal: 6.276 ± 0.0
0.349ValTrp: 0.349 ± 0.0
2.092ValTyr: 2.092 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.697TrpAla: 0.697 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.395TrpAsp: 1.395 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.697TrpPhe: 0.697 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.697TrpHis: 0.697 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.743TrpLeu: 1.743 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.349TrpAsn: 0.349 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.697TrpArg: 0.697 ± 0.0
1.395TrpSer: 1.395 ± 0.0
0.349TrpThr: 0.349 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.349TrpTyr: 0.349 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.138TyrAla: 3.138 ± 0.0
1.395TyrCys: 1.395 ± 0.0
2.092TyrAsp: 2.092 ± 0.0
0.697TyrGlu: 0.697 ± 0.0
2.092TyrPhe: 2.092 ± 0.0
2.789TyrGly: 2.789 ± 0.0
0.349TyrHis: 0.349 ± 0.0
2.092TyrIle: 2.092 ± 0.0
3.138TyrLys: 3.138 ± 0.0
3.835TyrLeu: 3.835 ± 0.0
1.395TyrMet: 1.395 ± 0.0
1.046TyrAsn: 1.046 ± 0.0
1.743TyrPro: 1.743 ± 0.0
1.395TyrGln: 1.395 ± 0.0
1.743TyrArg: 1.743 ± 0.0
2.092TyrSer: 2.092 ± 0.0
2.092TyrThr: 2.092 ± 0.0
2.441TyrVal: 2.441 ± 0.0
0.697TyrTrp: 0.697 ± 0.0
1.046TyrTyr: 1.046 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2869 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski