Amino acid dipepetide frequency for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.412AlaAla: 6.412 ± 0.034	1.369AlaCys: 1.369 ± 0.009	2.947AlaAsp: 2.947 ± 0.014	4.817AlaGlu: 4.817 ± 0.024	2.604AlaPhe: 2.604 ± 0.013	4.567AlaGly: 4.567 ± 0.021	1.533AlaHis: 1.533 ± 0.01	2.812AlaIle: 2.812 ± 0.015	3.514AlaLys: 3.514 ± 0.017	7.023AlaLeu: 7.023 ± 0.027	1.497AlaMet: 1.497 ± 0.008	2.045AlaAsn: 2.045 ± 0.012	3.993AlaPro: 3.993 ± 0.021	3.251AlaGln: 3.251 ± 0.018	3.586AlaArg: 3.586 ± 0.018	5.697AlaSer: 5.697 ± 0.019	3.581AlaThr: 3.581 ± 0.019	4.696AlaVal: 4.696 ± 0.017	0.791AlaTrp: 0.791 ± 0.007	1.535AlaTyr: 1.535 ± 0.01	0.002AlaXaa: 0.002 ± 0.0
Cys	1.193CysAla: 1.193 ± 0.009	0.62CysCys: 0.62 ± 0.009	1.011CysAsp: 1.011 ± 0.01	1.287CysGlu: 1.287 ± 0.012	0.824CysPhe: 0.824 ± 0.006	1.701CysGly: 1.701 ± 0.014	0.666CysHis: 0.666 ± 0.007	0.966CysIle: 0.966 ± 0.009	1.176CysLys: 1.176 ± 0.01	2.155CysLeu: 2.155 ± 0.013	0.416CysMet: 0.416 ± 0.005	0.814CysAsn: 0.814 ± 0.008	1.347CysPro: 1.347 ± 0.013	1.073CysGln: 1.073 ± 0.009	1.271CysArg: 1.271 ± 0.01	1.979CysSer: 1.979 ± 0.013	1.087CysThr: 1.087 ± 0.009	1.29CysVal: 1.29 ± 0.011	0.283CysTrp: 0.283 ± 0.005	0.57CysTyr: 0.57 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.891AspAla: 2.891 ± 0.014	1.067AspCys: 1.067 ± 0.01	2.708AspAsp: 2.708 ± 0.015	3.545AspGlu: 3.545 ± 0.017	2.136AspPhe: 2.136 ± 0.01	3.345AspGly: 3.345 ± 0.019	1.147AspHis: 1.147 ± 0.008	2.656AspIle: 2.656 ± 0.013	2.589AspLys: 2.589 ± 0.013	5.068AspLeu: 5.068 ± 0.019	1.118AspMet: 1.118 ± 0.008	1.709AspAsn: 1.709 ± 0.011	2.914AspPro: 2.914 ± 0.012	1.852AspGln: 1.852 ± 0.01	2.439AspArg: 2.439 ± 0.013	4.241AspSer: 4.241 ± 0.018	2.509AspThr: 2.509 ± 0.01	3.127AspVal: 3.127 ± 0.011	0.626AspTrp: 0.626 ± 0.006	1.511AspTyr: 1.511 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.278GluAla: 5.278 ± 0.025	1.465GluCys: 1.465 ± 0.018	4.53GluAsp: 4.53 ± 0.019	8.075GluGlu: 8.075 ± 0.034	2.09GluPhe: 2.09 ± 0.01	4.211GluGly: 4.211 ± 0.018	1.548GluHis: 1.548 ± 0.009	3.238GluIle: 3.238 ± 0.016	5.554GluLys: 5.554 ± 0.031	6.568GluLeu: 6.568 ± 0.025	1.709GluMet: 1.709 ± 0.01	3.224GluAsn: 3.224 ± 0.016	3.201GluPro: 3.201 ± 0.018	3.222GluGln: 3.222 ± 0.017	4.043GluArg: 4.043 ± 0.02	4.456GluSer: 4.456 ± 0.016	3.475GluThr: 3.475 ± 0.015	4.215GluVal: 4.215 ± 0.018	0.706GluTrp: 0.706 ± 0.006	1.645GluTyr: 1.645 ± 0.012	0.001GluXaa: 0.001 ± 0.0
Phe	1.971PheAla: 1.971 ± 0.01	0.911PheCys: 0.911 ± 0.008	1.708PheAsp: 1.708 ± 0.01	2.049PheGlu: 2.049 ± 0.01	1.553PhePhe: 1.553 ± 0.012	2.203PheGly: 2.203 ± 0.014	1.037PheHis: 1.037 ± 0.008	1.809PheIle: 1.809 ± 0.012	1.827PheLys: 1.827 ± 0.01	3.996PheLeu: 3.996 ± 0.019	0.776PheMet: 0.776 ± 0.006	1.343PheAsn: 1.343 ± 0.008	1.974PhePro: 1.974 ± 0.012	1.805PheGln: 1.805 ± 0.009	2.001PheArg: 2.001 ± 0.014	3.395PheSer: 3.395 ± 0.014	2.039PheThr: 2.039 ± 0.011	2.12PheVal: 2.12 ± 0.012	0.489PheTrp: 0.489 ± 0.005	1.165PheTyr: 1.165 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.299GlyAla: 4.299 ± 0.021	1.243GlyCys: 1.243 ± 0.01	3.148GlyAsp: 3.148 ± 0.017	4.163GlyGlu: 4.163 ± 0.021	2.391GlyPhe: 2.391 ± 0.014	4.784GlyGly: 4.784 ± 0.027	1.685GlyHis: 1.685 ± 0.01	2.788GlyIle: 2.788 ± 0.013	3.868GlyLys: 3.868 ± 0.02	5.824GlyLeu: 5.824 ± 0.024	1.32GlyMet: 1.32 ± 0.009	2.358GlyAsn: 2.358 ± 0.011	4.101GlyPro: 4.101 ± 0.035	2.756GlyGln: 2.756 ± 0.015	3.701GlyArg: 3.701 ± 0.019	5.782GlySer: 5.782 ± 0.024	3.603GlyThr: 3.603 ± 0.014	3.554GlyVal: 3.554 ± 0.017	0.794GlyTrp: 0.794 ± 0.008	1.751GlyTyr: 1.751 ± 0.013	0.003GlyXaa: 0.003 ± 0.0
His	1.337HisAla: 1.337 ± 0.009	0.732HisCys: 0.732 ± 0.006	0.904HisAsp: 0.904 ± 0.006	1.343HisGlu: 1.343 ± 0.008	1.08HisPhe: 1.08 ± 0.007	1.535HisGly: 1.535 ± 0.009	0.902HisHis: 0.902 ± 0.009	1.269HisIle: 1.269 ± 0.009	1.295HisLys: 1.295 ± 0.01	2.922HisLeu: 2.922 ± 0.013	0.593HisMet: 0.593 ± 0.005	0.886HisAsn: 0.886 ± 0.007	1.637HisPro: 1.637 ± 0.011	1.372HisGln: 1.372 ± 0.012	1.6HisArg: 1.6 ± 0.01	2.324HisSer: 2.324 ± 0.014	1.539HisThr: 1.539 ± 0.014	1.509HisVal: 1.509 ± 0.009	0.344HisTrp: 0.344 ± 0.004	0.805HisTyr: 0.805 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.611IleAla: 2.611 ± 0.014	1.06IleCys: 1.06 ± 0.009	2.069IleAsp: 2.069 ± 0.011	2.667IleGlu: 2.667 ± 0.016	1.872IlePhe: 1.872 ± 0.012	2.227IleGly: 2.227 ± 0.012	1.384IleHis: 1.384 ± 0.012	2.395IleIle: 2.395 ± 0.015	2.714IleLys: 2.714 ± 0.017	4.575IleLeu: 4.575 ± 0.019	1.003IleMet: 1.003 ± 0.009	1.87IleAsn: 1.87 ± 0.012	2.649IlePro: 2.649 ± 0.013	2.318IleGln: 2.318 ± 0.013	2.422IleArg: 2.422 ± 0.011	3.718IleSer: 3.718 ± 0.016	2.586IleThr: 2.586 ± 0.017	2.502IleVal: 2.502 ± 0.017	0.502IleTrp: 0.502 ± 0.005	1.382IleTyr: 1.382 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	4.086LysAla: 4.086 ± 0.021	1.18LysCys: 1.18 ± 0.011	3.247LysAsp: 3.247 ± 0.019	5.251LysGlu: 5.251 ± 0.03	1.757LysPhe: 1.757 ± 0.01	3.311LysGly: 3.311 ± 0.02	1.434LysHis: 1.434 ± 0.01	2.849LysIle: 2.849 ± 0.016	4.805LysLys: 4.805 ± 0.027	5.29LysLeu: 5.29 ± 0.021	1.458LysMet: 1.458 ± 0.009	2.459LysAsn: 2.459 ± 0.013	3.151LysPro: 3.151 ± 0.021	2.689LysGln: 2.689 ± 0.015	3.351LysArg: 3.351 ± 0.014	3.966LysSer: 3.966 ± 0.02	3.154LysThr: 3.154 ± 0.015	3.525LysVal: 3.525 ± 0.017	0.613LysTrp: 0.613 ± 0.006	1.613LysTyr: 1.613 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.738LeuAla: 6.738 ± 0.026	2.168LeuCys: 2.168 ± 0.012	4.781LeuAsp: 4.781 ± 0.016	7.28LeuGlu: 7.28 ± 0.032	3.341LeuPhe: 3.341 ± 0.018	5.778LeuGly: 5.778 ± 0.022	2.741LeuHis: 2.741 ± 0.016	3.884LeuIle: 3.884 ± 0.018	5.935LeuLys: 5.935 ± 0.025	10.6LeuLeu: 10.6 ± 0.04	2.006LeuMet: 2.006 ± 0.01	3.551LeuAsn: 3.551 ± 0.015	5.93LeuPro: 5.93 ± 0.021	5.86LeuGln: 5.86 ± 0.029	5.877LeuArg: 5.877 ± 0.024	7.937LeuSer: 7.937 ± 0.026	5.086LeuThr: 5.086 ± 0.017	5.429LeuVal: 5.429 ± 0.021	1.112LeuTrp: 1.112 ± 0.009	2.535LeuTyr: 2.535 ± 0.013	0.001LeuXaa: 0.001 ± 0.0
Met	1.872MetAla: 1.872 ± 0.01	0.401MetCys: 0.401 ± 0.004	1.265MetAsp: 1.265 ± 0.008	1.914MetGlu: 1.914 ± 0.01	0.728MetPhe: 0.728 ± 0.007	1.29MetGly: 1.29 ± 0.008	0.481MetHis: 0.481 ± 0.004	0.855MetIle: 0.855 ± 0.007	1.471MetLys: 1.471 ± 0.009	1.984MetLeu: 1.984 ± 0.012	0.574MetMet: 0.574 ± 0.006	0.918MetAsn: 0.918 ± 0.007	1.101MetPro: 1.101 ± 0.007	0.941MetGln: 0.941 ± 0.007	1.046MetArg: 1.046 ± 0.008	1.568MetSer: 1.568 ± 0.009	1.137MetThr: 1.137 ± 0.008	1.381MetVal: 1.381 ± 0.01	0.24MetTrp: 0.24 ± 0.003	0.555MetTyr: 0.555 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.081AsnAla: 2.081 ± 0.01	0.833AsnCys: 0.833 ± 0.008	1.558AsnAsp: 1.558 ± 0.011	2.278AsnGlu: 2.278 ± 0.012	1.485AsnPhe: 1.485 ± 0.009	2.477AsnGly: 2.477 ± 0.015	0.969AsnHis: 0.969 ± 0.007	2.142AsnIle: 2.142 ± 0.012	2.252AsnLys: 2.252 ± 0.013	3.76AsnLeu: 3.76 ± 0.016	0.921AsnMet: 0.921 ± 0.007	1.547AsnAsn: 1.547 ± 0.01	2.181AsnPro: 2.181 ± 0.012	1.697AsnGln: 1.697 ± 0.01	1.859AsnArg: 1.859 ± 0.011	3.165AsnSer: 3.165 ± 0.016	1.986AsnThr: 1.986 ± 0.01	2.222AsnVal: 2.222 ± 0.012	0.456AsnTrp: 0.456 ± 0.005	1.133AsnTyr: 1.133 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.713ProAla: 4.713 ± 0.022	1.118ProCys: 1.118 ± 0.01	2.788ProAsp: 2.788 ± 0.014	4.439ProGlu: 4.439 ± 0.016	1.885ProPhe: 1.885 ± 0.011	5.162ProGly: 5.162 ± 0.045	1.447ProHis: 1.447 ± 0.01	1.917ProIle: 1.917 ± 0.012	2.785ProLys: 2.785 ± 0.017	5.174ProLeu: 5.174 ± 0.019	1.041ProMet: 1.041 ± 0.008	1.829ProAsn: 1.829 ± 0.011	5.837ProPro: 5.837 ± 0.043	2.803ProGln: 2.803 ± 0.017	3.255ProArg: 3.255 ± 0.018	5.692ProSer: 5.692 ± 0.027	3.11ProThr: 3.11 ± 0.015	3.8ProVal: 3.8 ± 0.019	0.676ProTrp: 0.676 ± 0.007	1.531ProTyr: 1.531 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	3.557GlnAla: 3.557 ± 0.02	0.947GlnCys: 0.947 ± 0.009	2.379GlnAsp: 2.379 ± 0.013	3.967GlnGlu: 3.967 ± 0.02	1.39GlnPhe: 1.39 ± 0.008	2.844GlnGly: 2.844 ± 0.015	1.327GlnHis: 1.327 ± 0.008	2.012GlnIle: 2.012 ± 0.012	3.027GlnLys: 3.027 ± 0.016	4.791GlnLeu: 4.791 ± 0.024	1.131GlnMet: 1.131 ± 0.008	1.873GlnAsn: 1.873 ± 0.012	2.799GlnPro: 2.799 ± 0.017	3.119GlnGln: 3.119 ± 0.03	2.99GlnArg: 2.99 ± 0.017	3.169GlnSer: 3.169 ± 0.015	2.324GlnThr: 2.324 ± 0.012	2.842GlnVal: 2.842 ± 0.014	0.554GlnTrp: 0.554 ± 0.006	1.166GlnTyr: 1.166 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	3.73ArgAla: 3.73 ± 0.016	1.209ArgCys: 1.209 ± 0.011	2.77ArgAsp: 2.77 ± 0.013	4.041ArgGlu: 4.041 ± 0.019	1.858ArgPhe: 1.858 ± 0.01	3.558ArgGly: 3.558 ± 0.023	1.537ArgHis: 1.537 ± 0.011	2.488ArgIle: 2.488 ± 0.012	3.72ArgLys: 3.72 ± 0.015	5.401ArgLeu: 5.401 ± 0.023	1.199ArgMet: 1.199 ± 0.007	2.134ArgAsn: 2.134 ± 0.012	3.182ArgPro: 3.182 ± 0.014	2.655ArgGln: 2.655 ± 0.015	4.245ArgArg: 4.245 ± 0.022	4.254ArgSer: 4.254 ± 0.023	2.827ArgThr: 2.827 ± 0.015	3.158ArgVal: 3.158 ± 0.015	0.685ArgTrp: 0.685 ± 0.007	1.436ArgTyr: 1.436 ± 0.008	0.001ArgXaa: 0.001 ± 0.0
Ser	5.279SerAla: 5.279 ± 0.022	1.803SerCys: 1.803 ± 0.014	3.934SerAsp: 3.934 ± 0.02	5.285SerGlu: 5.285 ± 0.021	3.039SerPhe: 3.039 ± 0.013	5.592SerGly: 5.592 ± 0.022	2.132SerHis: 2.132 ± 0.014	3.237SerIle: 3.237 ± 0.014	4.146SerLys: 4.146 ± 0.02	8.197SerLeu: 8.197 ± 0.026	1.611SerMet: 1.611 ± 0.009	2.739SerAsn: 2.739 ± 0.014	6.002SerPro: 6.002 ± 0.033	3.912SerGln: 3.912 ± 0.018	4.545SerArg: 4.545 ± 0.023	9.367SerSer: 9.367 ± 0.053	4.475SerThr: 4.475 ± 0.02	4.865SerVal: 4.865 ± 0.016	1.055SerTrp: 1.055 ± 0.009	2.061SerTyr: 2.061 ± 0.012	0.001SerXaa: 0.001 ± 0.0
Thr	3.777ThrAla: 3.777 ± 0.015	1.277ThrCys: 1.277 ± 0.013	2.513ThrAsp: 2.513 ± 0.011	3.58ThrGlu: 3.58 ± 0.014	2.084ThrPhe: 2.084 ± 0.012	3.58ThrGly: 3.58 ± 0.016	1.327ThrHis: 1.327 ± 0.009	2.379ThrIle: 2.379 ± 0.014	2.705ThrLys: 2.705 ± 0.016	5.3ThrLeu: 5.3 ± 0.018	1.112ThrMet: 1.112 ± 0.009	1.769ThrAsn: 1.769 ± 0.01	3.599ThrPro: 3.599 ± 0.022	2.307ThrGln: 2.307 ± 0.011	2.47ThrArg: 2.47 ± 0.012	4.66ThrSer: 4.66 ± 0.02	3.007ThrThr: 3.007 ± 0.022	3.861ThrVal: 3.861 ± 0.02	0.687ThrTrp: 0.687 ± 0.007	1.422ThrTyr: 1.422 ± 0.009	0.001ThrXaa: 0.001 ± 0.0
Val	4.264ValAla: 4.264 ± 0.017	1.409ValCys: 1.409 ± 0.01	2.986ValAsp: 2.986 ± 0.013	3.914ValGlu: 3.914 ± 0.02	2.4ValPhe: 2.4 ± 0.013	3.369ValGly: 3.369 ± 0.015	1.559ValHis: 1.559 ± 0.009	2.908ValIle: 2.908 ± 0.015	3.465ValLys: 3.465 ± 0.02	6.118ValLeu: 6.118 ± 0.021	1.315ValMet: 1.315 ± 0.007	2.286ValAsn: 2.286 ± 0.014	3.602ValPro: 3.602 ± 0.016	2.754ValGln: 2.754 ± 0.015	3.046ValArg: 3.046 ± 0.013	4.859ValSer: 4.859 ± 0.019	3.77ValThr: 3.77 ± 0.023	3.946ValVal: 3.946 ± 0.017	0.704ValTrp: 0.704 ± 0.006	1.625ValTyr: 1.625 ± 0.009	0.001ValXaa: 0.001 ± 0.0
Trp	0.775TrpAla: 0.775 ± 0.007	0.244TrpCys: 0.244 ± 0.004	0.648TrpAsp: 0.648 ± 0.007	0.81TrpGlu: 0.81 ± 0.007	0.444TrpPhe: 0.444 ± 0.005	0.718TrpGly: 0.718 ± 0.008	0.307TrpHis: 0.307 ± 0.004	0.545TrpIle: 0.545 ± 0.006	0.808TrpLys: 0.808 ± 0.007	1.191TrpLeu: 1.191 ± 0.009	0.319TrpMet: 0.319 ± 0.004	0.539TrpAsn: 0.539 ± 0.005	0.515TrpPro: 0.515 ± 0.005	0.531TrpGln: 0.531 ± 0.005	0.715TrpArg: 0.715 ± 0.006	0.869TrpSer: 0.869 ± 0.007	0.675TrpThr: 0.675 ± 0.007	0.686TrpVal: 0.686 ± 0.007	0.202TrpTrp: 0.202 ± 0.003	0.335TrpTyr: 0.335 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.406TyrAla: 1.406 ± 0.009	0.672TyrCys: 0.672 ± 0.006	1.305TyrAsp: 1.305 ± 0.009	1.746TyrGlu: 1.746 ± 0.01	1.211TyrPhe: 1.211 ± 0.008	1.663TyrGly: 1.663 ± 0.01	0.766TyrHis: 0.766 ± 0.006	1.378TyrIle: 1.378 ± 0.01	1.529TyrLys: 1.529 ± 0.016	2.631TyrLeu: 2.631 ± 0.012	0.603TyrMet: 0.603 ± 0.005	1.109TyrAsn: 1.109 ± 0.008	1.286TyrPro: 1.286 ± 0.009	1.291TyrGln: 1.291 ± 0.009	1.624TyrArg: 1.624 ± 0.01	2.178TyrSer: 2.178 ± 0.012	1.448TyrThr: 1.448 ± 0.012	1.57TyrVal: 1.57 ± 0.01	0.359TyrTrp: 0.359 ± 0.006	0.944TyrTyr: 0.944 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.413XaaXaa: 0.413 ± 0.038

Statistics based on 39639 proteins (22155886 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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