Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida; Candida parapsilosis

Average proteome isoelectric point is 6.35

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5777 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G8B757|G8B757_CANPC Histone H2A OS=Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) OX=578454 GN=CPAR2_103280 PE=3 SV=1
MM1 pKa = 7.76GDD3 pKa = 3.66HH4 pKa = 6.45VSEE7 pKa = 4.3IAWDD11 pKa = 3.88KK12 pKa = 11.22VDD14 pKa = 4.97SALTSNLLSKK24 pKa = 9.3ITNSLEE30 pKa = 3.79CSICSEE36 pKa = 4.01IMLAPMTTEE45 pKa = 4.74CGHH48 pKa = 5.47SFCYY52 pKa = 10.07EE53 pKa = 4.25CLHH56 pKa = 6.24QWFQNKK62 pKa = 8.68INCPTCRR69 pKa = 11.84HH70 pKa = 6.53EE71 pKa = 4.6IQTKK75 pKa = 9.13PALNMKK81 pKa = 10.29LNDD84 pKa = 3.48VSKK87 pKa = 11.09SLAEE91 pKa = 4.41LIIDD95 pKa = 4.27ARR97 pKa = 11.84LDD99 pKa = 3.63PNVDD103 pKa = 2.93SFRR106 pKa = 11.84ARR108 pKa = 11.84KK109 pKa = 8.93KK110 pKa = 10.65DD111 pKa = 3.36AMSKK115 pKa = 10.44YY116 pKa = 9.64EE117 pKa = 3.79SHH119 pKa = 6.67AKK121 pKa = 9.25KK122 pKa = 10.32KK123 pKa = 10.47RR124 pKa = 11.84VFGEE128 pKa = 4.0LFCGYY133 pKa = 10.23SLALIDD139 pKa = 5.68DD140 pKa = 3.97SDD142 pKa = 3.95GVPRR146 pKa = 11.84CGNCLWEE153 pKa = 4.08AHH155 pKa = 5.69GTVCLHH161 pKa = 6.31CGSRR165 pKa = 11.84FRR167 pKa = 11.84NTDD170 pKa = 4.3LIRR173 pKa = 11.84GGGHH177 pKa = 7.61DD178 pKa = 5.98DD179 pKa = 5.89DD180 pKa = 7.59DD181 pKa = 7.46DD182 pKa = 6.48DD183 pKa = 7.35DD184 pKa = 4.77EE185 pKa = 6.8DD186 pKa = 4.68EE187 pKa = 4.52EE188 pKa = 5.23EE189 pKa = 4.96FYY191 pKa = 11.28QDD193 pKa = 3.15VPPAEE198 pKa = 4.21DD199 pKa = 4.88HH200 pKa = 6.77YY201 pKa = 11.83DD202 pKa = 3.55SDD204 pKa = 5.1DD205 pKa = 3.97SFVDD209 pKa = 3.21SRR211 pKa = 11.84TAEE214 pKa = 3.95EE215 pKa = 4.22LLEE218 pKa = 4.72EE219 pKa = 4.12IHH221 pKa = 7.93DD222 pKa = 5.0NGPEE226 pKa = 4.31DD227 pKa = 5.24NNDD230 pKa = 3.6DD231 pKa = 3.92QPNATSSDD239 pKa = 3.43EE240 pKa = 5.04DD241 pKa = 4.84DD242 pKa = 5.26DD243 pKa = 6.74DD244 pKa = 4.53GAASFRR250 pKa = 11.84NWLSGSQPRR259 pKa = 11.84SHH261 pKa = 7.49IIYY264 pKa = 10.49VDD266 pKa = 3.57DD267 pKa = 3.88TDD269 pKa = 6.09SEE271 pKa = 4.56FEE273 pKa = 4.24YY274 pKa = 11.1NPRR277 pKa = 11.84IYY279 pKa = 10.65SDD281 pKa = 3.63SDD283 pKa = 3.26EE284 pKa = 5.75DD285 pKa = 4.1SPQQIHH291 pKa = 6.59FGGGPGGHH299 pKa = 6.58VIIDD303 pKa = 4.04LDD305 pKa = 4.02ADD307 pKa = 3.76EE308 pKa = 5.85DD309 pKa = 4.63GNDD312 pKa = 3.87SEE314 pKa = 6.37LIDD317 pKa = 4.09ALADD321 pKa = 3.91FQHH324 pKa = 6.41GVSEE328 pKa = 4.59DD329 pKa = 3.52EE330 pKa = 4.19ANEE333 pKa = 4.08DD334 pKa = 3.54FRR336 pKa = 11.84SLHH339 pKa = 6.4EE340 pKa = 4.14DD341 pKa = 3.54HH342 pKa = 7.24EE343 pKa = 4.56NDD345 pKa = 3.55YY346 pKa = 11.42YY347 pKa = 11.45DD348 pKa = 5.68RR349 pKa = 11.84SDD351 pKa = 3.68DD352 pKa = 4.25DD353 pKa = 4.09EE354 pKa = 6.85GGEE357 pKa = 4.19EE358 pKa = 4.93DD359 pKa = 3.75EE360 pKa = 5.6DD361 pKa = 4.2GHH363 pKa = 7.05GSHH366 pKa = 7.09SDD368 pKa = 3.61PDD370 pKa = 3.81PDD372 pKa = 4.19EE373 pKa = 5.76YY374 pKa = 11.61YY375 pKa = 10.99DD376 pKa = 4.34DD377 pKa = 5.28YY378 pKa = 11.46EE379 pKa = 6.59AEE381 pKa = 4.44DD382 pKa = 4.23HH383 pKa = 7.69DD384 pKa = 5.08IDD386 pKa = 5.1QDD388 pKa = 4.13DD389 pKa = 3.87VDD391 pKa = 4.29VDD393 pKa = 3.56VDD395 pKa = 3.61QNEE398 pKa = 4.22YY399 pKa = 10.99EE400 pKa = 5.31DD401 pKa = 5.54YY402 pKa = 11.34DD403 pKa = 5.21DD404 pKa = 5.64NYY406 pKa = 11.05NDD408 pKa = 4.26NDD410 pKa = 4.67DD411 pKa = 4.34YY412 pKa = 12.07DD413 pKa = 5.48DD414 pKa = 4.38GQEE417 pKa = 4.56TDD419 pKa = 4.1GNWW422 pKa = 2.86

Molecular weight: 47.78 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G8BAH0|G8BAH0_CANPC Uncharacterized protein OS=Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) OX=578454 GN=CPAR2_805920 PE=4 SV=1
MM1 pKa = 7.26SLSRR5 pKa = 11.84PTTPIGDD12 pKa = 3.12RR13 pKa = 11.84RR14 pKa = 11.84QTNRR18 pKa = 11.84RR19 pKa = 11.84HH20 pKa = 5.15SRR22 pKa = 11.84RR23 pKa = 11.84SSGIPLPSQSPHH35 pKa = 6.91HH36 pKa = 6.44YY37 pKa = 10.12PVDD40 pKa = 4.0ADD42 pKa = 4.47NLPMDD47 pKa = 4.81CPEE50 pKa = 4.15IQNKK54 pKa = 9.31FKK56 pKa = 10.95DD57 pKa = 3.5IADD60 pKa = 3.92GLEE63 pKa = 4.13DD64 pKa = 4.6LDD66 pKa = 4.84VNVRR70 pKa = 11.84DD71 pKa = 4.56LNHH74 pKa = 6.03IHH76 pKa = 6.41NAVASQFNEE85 pKa = 3.97SFASFLYY92 pKa = 10.68GLSITMWCVDD102 pKa = 4.0LPKK105 pKa = 10.68CPSRR109 pKa = 11.84KK110 pKa = 9.2AWQKK114 pKa = 9.44LQMRR118 pKa = 11.84KK119 pKa = 9.24RR120 pKa = 11.84KK121 pKa = 9.51KK122 pKa = 8.69EE123 pKa = 3.73QIAKK127 pKa = 8.89VRR129 pKa = 11.84KK130 pKa = 8.67EE131 pKa = 3.59IEE133 pKa = 3.66GAEE136 pKa = 4.0RR137 pKa = 11.84LNAEE141 pKa = 4.6LKK143 pKa = 10.59EE144 pKa = 4.18KK145 pKa = 9.97VAKK148 pKa = 6.98EE149 pKa = 4.19TRR151 pKa = 11.84PIMYY155 pKa = 9.13SRR157 pKa = 11.84PMGTQLPKK165 pKa = 10.25RR166 pKa = 11.84ARR168 pKa = 11.84PNNEE172 pKa = 3.43NAKK175 pKa = 10.46PGINLNKK182 pKa = 9.51PSAPATRR189 pKa = 11.84VSRR192 pKa = 11.84IPQPVSGMLRR202 pKa = 11.84TQPGQTISRR211 pKa = 11.84NNAPNLDD218 pKa = 3.49QPPRR222 pKa = 11.84YY223 pKa = 9.16MRR225 pKa = 11.84GLFNNGVQSTPIGPNSRR242 pKa = 11.84VQKK245 pKa = 8.86PQRR248 pKa = 11.84AQHH251 pKa = 5.84SGRR254 pKa = 11.84RR255 pKa = 11.84PPFRR259 pKa = 5.79

Molecular weight: 29.4 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5777

0

5777

2913513

33

4846

504.3

56.75

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.795 ± 0.027

1.085 ± 0.01

6.032 ± 0.024

6.477 ± 0.036

4.343 ± 0.022

5.486 ± 0.036

2.297 ± 0.013

6.315 ± 0.025

7.033 ± 0.031

9.121 ± 0.034

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.861 ± 0.011

5.732 ± 0.024

4.537 ± 0.026

4.584 ± 0.03

4.144 ± 0.02

8.953 ± 0.044

5.873 ± 0.033

5.875 ± 0.021

1.002 ± 0.011

3.455 ± 0.018
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski