Amino acid dipepetide frequency for Hirundo rustica rustica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.932AlaAla: 7.932 ± 0.038	1.264AlaCys: 1.264 ± 0.011	2.872AlaAsp: 2.872 ± 0.016	5.162AlaGlu: 5.162 ± 0.03	2.687AlaPhe: 2.687 ± 0.016	4.852AlaGly: 4.852 ± 0.029	1.578AlaHis: 1.578 ± 0.011	2.934AlaIle: 2.934 ± 0.015	3.715AlaLys: 3.715 ± 0.018	7.412AlaLeu: 7.412 ± 0.029	1.559AlaMet: 1.559 ± 0.014	2.232AlaAsn: 2.232 ± 0.013	3.988AlaPro: 3.988 ± 0.023	3.396AlaGln: 3.396 ± 0.02	3.814AlaArg: 3.814 ± 0.023	4.743AlaSer: 4.743 ± 0.025	3.682AlaThr: 3.682 ± 0.023	5.487AlaVal: 5.487 ± 0.024	0.914AlaTrp: 0.914 ± 0.01	1.296AlaTyr: 1.296 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.276CysAla: 1.276 ± 0.011	0.539CysCys: 0.539 ± 0.008	0.816CysAsp: 0.816 ± 0.01	1.201CysGlu: 1.201 ± 0.01	0.717CysPhe: 0.717 ± 0.008	2.019CysGly: 2.019 ± 0.025	0.707CysHis: 0.707 ± 0.009	0.875CysIle: 0.875 ± 0.01	1.044CysLys: 1.044 ± 0.01	2.034CysLeu: 2.034 ± 0.014	0.375CysMet: 0.375 ± 0.005	0.608CysAsn: 0.608 ± 0.008	1.477CysPro: 1.477 ± 0.015	1.099CysGln: 1.099 ± 0.011	1.353CysArg: 1.353 ± 0.012	1.695CysSer: 1.695 ± 0.013	1.037CysThr: 1.037 ± 0.009	1.095CysVal: 1.095 ± 0.011	0.315CysTrp: 0.315 ± 0.006	0.485CysTyr: 0.485 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.948AspAla: 2.948 ± 0.016	1.056AspCys: 1.056 ± 0.009	2.605AspAsp: 2.605 ± 0.021	3.195AspGlu: 3.195 ± 0.023	1.849AspPhe: 1.849 ± 0.014	3.324AspGly: 3.324 ± 0.025	0.935AspHis: 0.935 ± 0.009	2.649AspIle: 2.649 ± 0.02	2.362AspLys: 2.362 ± 0.017	4.972AspLeu: 4.972 ± 0.024	1.26AspMet: 1.26 ± 0.012	1.658AspAsn: 1.658 ± 0.015	3.043AspPro: 3.043 ± 0.024	1.681AspGln: 1.681 ± 0.016	2.411AspArg: 2.411 ± 0.017	3.722AspSer: 3.722 ± 0.024	2.552AspThr: 2.552 ± 0.018	2.923AspVal: 2.923 ± 0.021	0.884AspTrp: 0.884 ± 0.018	1.28AspTyr: 1.28 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.354GluAla: 5.354 ± 0.028	1.801GluCys: 1.801 ± 0.024	4.107GluAsp: 4.107 ± 0.027	9.126GluGlu: 9.126 ± 0.083	1.777GluPhe: 1.777 ± 0.013	4.589GluGly: 4.589 ± 0.026	1.671GluHis: 1.671 ± 0.014	3.484GluIle: 3.484 ± 0.023	5.747GluLys: 5.747 ± 0.037	6.72GluLeu: 6.72 ± 0.033	1.751GluMet: 1.751 ± 0.015	2.711GluAsn: 2.711 ± 0.019	3.038GluPro: 3.038 ± 0.022	3.693GluGln: 3.693 ± 0.027	5.159GluArg: 5.159 ± 0.043	4.166GluSer: 4.166 ± 0.023	3.655GluThr: 3.655 ± 0.025	4.23GluVal: 4.23 ± 0.023	1.151GluTrp: 1.151 ± 0.013	1.355GluTyr: 1.355 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	2.04PheAla: 2.04 ± 0.012	0.79PheCys: 0.79 ± 0.007	1.253PheAsp: 1.253 ± 0.011	1.821PheGlu: 1.821 ± 0.012	1.483PhePhe: 1.483 ± 0.012	2.243PheGly: 2.243 ± 0.016	0.968PheHis: 0.968 ± 0.008	1.523PheIle: 1.523 ± 0.011	1.709PheLys: 1.709 ± 0.011	3.908PheLeu: 3.908 ± 0.026	0.62PheMet: 0.62 ± 0.007	1.317PheAsn: 1.317 ± 0.011	1.73PhePro: 1.73 ± 0.02	1.584PheGln: 1.584 ± 0.012	1.796PheArg: 1.796 ± 0.012	3.241PheSer: 3.241 ± 0.019	1.969PheThr: 1.969 ± 0.013	1.956PheVal: 1.956 ± 0.014	0.618PheTrp: 0.618 ± 0.008	0.868PheTyr: 0.868 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.06GlyAla: 4.06 ± 0.024	1.28GlyCys: 1.28 ± 0.011	3.01GlyAsp: 3.01 ± 0.026	5.46GlyGlu: 5.46 ± 0.042	2.495GlyPhe: 2.495 ± 0.018	4.598GlyGly: 4.598 ± 0.035	1.69GlyHis: 1.69 ± 0.013	3.461GlyIle: 3.461 ± 0.031	4.462GlyLys: 4.462 ± 0.03	5.845GlyLeu: 5.845 ± 0.035	1.71GlyMet: 1.71 ± 0.023	2.708GlyAsn: 2.708 ± 0.034	3.885GlyPro: 3.885 ± 0.031	3.033GlyGln: 3.033 ± 0.023	3.854GlyArg: 3.854 ± 0.02	5.545GlySer: 5.545 ± 0.03	3.823GlyThr: 3.823 ± 0.029	3.863GlyVal: 3.863 ± 0.03	1.245GlyTrp: 1.245 ± 0.016	1.703GlyTyr: 1.703 ± 0.012	0.0GlyXaa: 0.0 ± 0.0
His	1.523HisAla: 1.523 ± 0.011	0.531HisCys: 0.531 ± 0.007	1.007HisAsp: 1.007 ± 0.009	1.173HisGlu: 1.173 ± 0.008	0.971HisPhe: 0.971 ± 0.008	1.803HisGly: 1.803 ± 0.018	0.915HisHis: 0.915 ± 0.015	1.258HisIle: 1.258 ± 0.011	1.376HisLys: 1.376 ± 0.011	2.865HisLeu: 2.865 ± 0.016	0.551HisMet: 0.551 ± 0.007	0.872HisAsn: 0.872 ± 0.008	1.629HisPro: 1.629 ± 0.019	1.865HisGln: 1.865 ± 0.019	1.671HisArg: 1.671 ± 0.015	1.92HisSer: 1.92 ± 0.015	1.76HisThr: 1.76 ± 0.019	1.44HisVal: 1.44 ± 0.011	0.581HisTrp: 0.581 ± 0.006	0.667HisTyr: 0.667 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	2.772IleAla: 2.772 ± 0.017	1.115IleCys: 1.115 ± 0.011	2.201IleAsp: 2.201 ± 0.015	2.655IleGlu: 2.655 ± 0.017	1.599IlePhe: 1.599 ± 0.013	2.226IleGly: 2.226 ± 0.022	2.007IleHis: 2.007 ± 0.024	2.701IleIle: 2.701 ± 0.024	2.771IleLys: 2.771 ± 0.017	4.537IleLeu: 4.537 ± 0.026	0.92IleMet: 0.92 ± 0.008	1.895IleAsn: 1.895 ± 0.014	3.486IlePro: 3.486 ± 0.047	2.347IleGln: 2.347 ± 0.016	2.765IleArg: 2.765 ± 0.024	3.464IleSer: 3.464 ± 0.018	2.593IleThr: 2.593 ± 0.016	2.672IleVal: 2.672 ± 0.02	0.752IleTrp: 0.752 ± 0.009	1.222IleTyr: 1.222 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.424LysAla: 4.424 ± 0.022	1.088LysCys: 1.088 ± 0.011	3.053LysAsp: 3.053 ± 0.018	5.175LysGlu: 5.175 ± 0.037	1.558LysPhe: 1.558 ± 0.014	4.049LysGly: 4.049 ± 0.024	1.367LysHis: 1.367 ± 0.011	2.833LysIle: 2.833 ± 0.02	4.619LysLys: 4.619 ± 0.034	5.083LysLeu: 5.083 ± 0.026	1.325LysMet: 1.325 ± 0.012	2.276LysAsn: 2.276 ± 0.021	3.06LysPro: 3.06 ± 0.025	2.575LysGln: 2.575 ± 0.016	3.666LysArg: 3.666 ± 0.023	3.89LysSer: 3.89 ± 0.021	2.926LysThr: 2.926 ± 0.017	3.438LysVal: 3.438 ± 0.016	1.122LysTrp: 1.122 ± 0.013	1.553LysTyr: 1.553 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.791LeuAla: 6.791 ± 0.029	1.976LeuCys: 1.976 ± 0.015	4.481LeuAsp: 4.481 ± 0.024	7.383LeuGlu: 7.383 ± 0.042	3.059LeuPhe: 3.059 ± 0.023	6.52LeuGly: 6.52 ± 0.038	2.546LeuHis: 2.546 ± 0.022	4.133LeuIle: 4.133 ± 0.023	5.599LeuLys: 5.599 ± 0.026	9.986LeuLeu: 9.986 ± 0.04	1.803LeuMet: 1.803 ± 0.012	3.245LeuAsn: 3.245 ± 0.018	5.609LeuPro: 5.609 ± 0.027	5.513LeuGln: 5.513 ± 0.027	5.616LeuArg: 5.616 ± 0.025	7.18LeuSer: 7.18 ± 0.033	4.82LeuThr: 4.82 ± 0.021	5.461LeuVal: 5.461 ± 0.025	1.584LeuTrp: 1.584 ± 0.012	2.363LeuTyr: 2.363 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	1.77MetAla: 1.77 ± 0.013	0.346MetCys: 0.346 ± 0.006	1.343MetAsp: 1.343 ± 0.017	1.911MetGlu: 1.911 ± 0.023	0.689MetPhe: 0.689 ± 0.01	1.455MetGly: 1.455 ± 0.015	0.548MetHis: 0.548 ± 0.006	0.959MetIle: 0.959 ± 0.01	1.265MetLys: 1.265 ± 0.011	1.803MetLeu: 1.803 ± 0.013	0.488MetMet: 0.488 ± 0.008	0.728MetAsn: 0.728 ± 0.008	1.01MetPro: 1.01 ± 0.012	0.965MetGln: 0.965 ± 0.01	1.058MetArg: 1.058 ± 0.009	1.574MetSer: 1.574 ± 0.011	1.03MetThr: 1.03 ± 0.011	1.492MetVal: 1.492 ± 0.013	0.283MetTrp: 0.283 ± 0.005	0.437MetTyr: 0.437 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.044AsnAla: 2.044 ± 0.013	0.764AsnCys: 0.764 ± 0.01	1.405AsnAsp: 1.405 ± 0.013	2.024AsnGlu: 2.024 ± 0.015	1.234AsnPhe: 1.234 ± 0.011	2.633AsnGly: 2.633 ± 0.035	0.749AsnHis: 0.749 ± 0.008	1.95AsnIle: 1.95 ± 0.015	2.035AsnLys: 2.035 ± 0.014	3.374AsnLeu: 3.374 ± 0.019	0.778AsnMet: 0.778 ± 0.008	1.494AsnAsn: 1.494 ± 0.014	2.405AsnPro: 2.405 ± 0.018	1.482AsnGln: 1.482 ± 0.011	1.925AsnArg: 1.925 ± 0.016	2.967AsnSer: 2.967 ± 0.017	2.036AsnThr: 2.036 ± 0.013	1.913AsnVal: 1.913 ± 0.012	0.811AsnTrp: 0.811 ± 0.021	0.885AsnTyr: 0.885 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	4.862ProAla: 4.862 ± 0.033	1.159ProCys: 1.159 ± 0.015	2.87ProAsp: 2.87 ± 0.018	4.543ProGlu: 4.543 ± 0.032	1.889ProPhe: 1.889 ± 0.012	4.951ProGly: 4.951 ± 0.06	1.513ProHis: 1.513 ± 0.012	2.112ProIle: 2.112 ± 0.015	2.76ProLys: 2.76 ± 0.022	5.189ProLeu: 5.189 ± 0.022	0.944ProMet: 0.944 ± 0.009	1.63ProAsn: 1.63 ± 0.016	4.757ProPro: 4.757 ± 0.041	3.15ProGln: 3.15 ± 0.021	3.138ProArg: 3.138 ± 0.021	4.642ProSer: 4.642 ± 0.032	3.126ProThr: 3.126 ± 0.02	4.356ProVal: 4.356 ± 0.021	0.879ProTrp: 0.879 ± 0.016	1.772ProTyr: 1.772 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	3.715GlnAla: 3.715 ± 0.021	0.987GlnCys: 0.987 ± 0.011	2.295GlnAsp: 2.295 ± 0.018	4.127GlnGlu: 4.127 ± 0.029	1.579GlnPhe: 1.579 ± 0.019	3.386GlnGly: 3.386 ± 0.02	1.306GlnHis: 1.306 ± 0.011	2.39GlnIle: 2.39 ± 0.016	2.894GlnLys: 2.894 ± 0.019	4.773GlnLeu: 4.773 ± 0.021	0.968GlnMet: 0.968 ± 0.01	1.819GlnAsn: 1.819 ± 0.013	2.539GlnPro: 2.539 ± 0.02	3.195GlnGln: 3.195 ± 0.03	3.17GlnArg: 3.17 ± 0.018	2.822GlnSer: 2.822 ± 0.016	2.309GlnThr: 2.309 ± 0.015	3.1GlnVal: 3.1 ± 0.018	0.861GlnTrp: 0.861 ± 0.01	1.26GlnTyr: 1.26 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.049ArgAla: 4.049 ± 0.017	1.158ArgCys: 1.158 ± 0.01	3.129ArgAsp: 3.129 ± 0.022	5.266ArgGlu: 5.266 ± 0.028	1.679ArgPhe: 1.679 ± 0.011	4.387ArgGly: 4.387 ± 0.032	1.646ArgHis: 1.646 ± 0.013	2.687ArgIle: 2.687 ± 0.024	3.779ArgLys: 3.779 ± 0.023	4.992ArgLeu: 4.992 ± 0.028	1.294ArgMet: 1.294 ± 0.01	2.23ArgAsn: 2.23 ± 0.016	3.412ArgPro: 3.412 ± 0.027	2.723ArgGln: 2.723 ± 0.016	4.993ArgArg: 4.993 ± 0.042	3.989ArgSer: 3.989 ± 0.024	2.65ArgThr: 2.65 ± 0.016	3.248ArgVal: 3.248 ± 0.019	1.043ArgTrp: 1.043 ± 0.011	1.457ArgTyr: 1.457 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	4.984SerAla: 4.984 ± 0.021	1.739SerCys: 1.739 ± 0.013	3.229SerAsp: 3.229 ± 0.023	4.412SerGlu: 4.412 ± 0.024	2.822SerPhe: 2.822 ± 0.018	4.905SerGly: 4.905 ± 0.031	2.221SerHis: 2.221 ± 0.016	3.245SerIle: 3.245 ± 0.035	4.265SerLys: 4.265 ± 0.019	7.282SerLeu: 7.282 ± 0.032	1.401SerMet: 1.401 ± 0.01	2.246SerAsn: 2.246 ± 0.014	5.68SerPro: 5.68 ± 0.031	3.792SerGln: 3.792 ± 0.022	4.16SerArg: 4.16 ± 0.024	7.979SerSer: 7.979 ± 0.051	3.926SerThr: 3.926 ± 0.02	4.273SerVal: 4.273 ± 0.021	1.192SerTrp: 1.192 ± 0.012	1.684SerTyr: 1.684 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.778ThrAla: 3.778 ± 0.021	1.161ThrCys: 1.161 ± 0.013	2.794ThrAsp: 2.794 ± 0.016	3.768ThrGlu: 3.768 ± 0.019	1.757ThrPhe: 1.757 ± 0.015	4.103ThrGly: 4.103 ± 0.026	1.34ThrHis: 1.34 ± 0.011	2.593ThrIle: 2.593 ± 0.019	2.432ThrLys: 2.432 ± 0.017	4.754ThrLeu: 4.754 ± 0.02	1.08ThrMet: 1.08 ± 0.009	1.618ThrAsn: 1.618 ± 0.011	3.474ThrPro: 3.474 ± 0.025	2.406ThrGln: 2.406 ± 0.015	3.109ThrArg: 3.109 ± 0.025	3.821ThrSer: 3.821 ± 0.025	2.775ThrThr: 2.775 ± 0.052	3.737ThrVal: 3.737 ± 0.021	1.187ThrTrp: 1.187 ± 0.011	1.22ThrTyr: 1.22 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.61ValAla: 4.61 ± 0.023	1.243ValCys: 1.243 ± 0.012	2.874ValAsp: 2.874 ± 0.018	3.998ValGlu: 3.998 ± 0.019	2.212ValPhe: 2.212 ± 0.014	3.047ValGly: 3.047 ± 0.02	1.566ValHis: 1.566 ± 0.011	2.977ValIle: 2.977 ± 0.021	3.562ValLys: 3.562 ± 0.02	6.2ValLeu: 6.2 ± 0.026	1.322ValMet: 1.322 ± 0.01	1.989ValAsn: 1.989 ± 0.013	4.015ValPro: 4.015 ± 0.025	3.032ValGln: 3.032 ± 0.016	3.354ValArg: 3.354 ± 0.019	4.837ValSer: 4.837 ± 0.024	3.973ValThr: 3.973 ± 0.031	3.968ValVal: 3.968 ± 0.032	1.002ValTrp: 1.002 ± 0.01	1.374ValTyr: 1.374 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	1.163TrpAla: 1.163 ± 0.011	0.254TrpCys: 0.254 ± 0.005	0.949TrpAsp: 0.949 ± 0.015	1.174TrpGlu: 1.174 ± 0.013	0.473TrpPhe: 0.473 ± 0.008	1.089TrpGly: 1.089 ± 0.011	0.298TrpHis: 0.298 ± 0.005	0.835TrpIle: 0.835 ± 0.011	1.285TrpLys: 1.285 ± 0.011	1.501TrpLeu: 1.501 ± 0.011	0.456TrpMet: 0.456 ± 0.01	0.739TrpAsn: 0.739 ± 0.024	0.916TrpPro: 0.916 ± 0.007	0.978TrpGln: 0.978 ± 0.011	1.162TrpArg: 1.162 ± 0.012	1.284TrpSer: 1.284 ± 0.03	0.771TrpThr: 0.771 ± 0.01	0.96TrpVal: 0.96 ± 0.011	0.225TrpTrp: 0.225 ± 0.005	0.468TrpTyr: 0.468 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.425TyrAla: 1.425 ± 0.01	0.515TyrCys: 0.515 ± 0.007	1.015TyrAsp: 1.015 ± 0.011	1.71TyrGlu: 1.71 ± 0.014	0.91TyrPhe: 0.91 ± 0.009	1.55TyrGly: 1.55 ± 0.013	0.808TyrHis: 0.808 ± 0.008	1.105TyrIle: 1.105 ± 0.011	1.396TyrLys: 1.396 ± 0.015	2.436TyrLeu: 2.436 ± 0.013	0.549TyrMet: 0.549 ± 0.006	0.895TyrAsn: 0.895 ± 0.01	1.089TyrPro: 1.089 ± 0.011	0.984TyrGln: 0.984 ± 0.01	1.634TyrArg: 1.634 ± 0.014	1.958TyrSer: 1.958 ± 0.013	1.495TyrThr: 1.495 ± 0.012	1.543TyrVal: 1.543 ± 0.012	0.33TyrTrp: 0.33 ± 0.007	0.699TyrTyr: 0.699 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.003XaaXaa: 0.003 ± 0.001

Statistics based on 34534 proteins (15462943 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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