Amino acid dipepetide frequency for Simian immunodeficiency virus (isolate TAN1) (SIV-cpz) (Chimpanzee immunodeficiency virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.556AlaAla: 3.556 ± 0.314
1.641AlaCys: 1.641 ± 0.666
2.188AlaAsp: 2.188 ± 0.743
4.376AlaGlu: 4.376 ± 0.869
0.547AlaPhe: 0.547 ± 0.336
8.479AlaGly: 8.479 ± 1.479
1.641AlaHis: 1.641 ± 0.443
3.556AlaIle: 3.556 ± 1.07
1.641AlaLys: 1.641 ± 0.472
4.376AlaLeu: 4.376 ± 0.644
2.188AlaMet: 2.188 ± 0.763
2.735AlaAsn: 2.735 ± 0.952
2.462AlaPro: 2.462 ± 1.027
3.829AlaGln: 3.829 ± 0.794
4.923AlaArg: 4.923 ± 1.14
3.829AlaSer: 3.829 ± 0.805
4.103AlaThr: 4.103 ± 1.037
4.65AlaVal: 4.65 ± 0.908
0.821AlaTrp: 0.821 ± 0.347
1.368AlaTyr: 1.368 ± 0.509
0.0AlaXaa: 0.0 ± 0.0
Cys
1.094CysAla: 1.094 ± 0.687
0.547CysCys: 0.547 ± 0.48
0.274CysAsp: 0.274 ± 0.257
0.274CysGlu: 0.274 ± 0.257
1.368CysPhe: 1.368 ± 0.789
1.368CysGly: 1.368 ± 0.601
1.094CysHis: 1.094 ± 0.493
1.094CysIle: 1.094 ± 0.673
1.915CysLys: 1.915 ± 0.766
0.0CysLeu: 0.0 ± 0.0
0.274CysMet: 0.274 ± 0.301
1.094CysAsn: 1.094 ± 0.687
0.821CysPro: 0.821 ± 0.42
1.094CysGln: 1.094 ± 0.204
1.641CysArg: 1.641 ± 0.674
1.094CysSer: 1.094 ± 0.787
1.915CysThr: 1.915 ± 0.34
1.641CysVal: 1.641 ± 0.466
1.368CysTrp: 1.368 ± 0.607
0.274CysTyr: 0.274 ± 0.326
0.0CysXaa: 0.0 ± 0.0
Asp
2.188AspAla: 2.188 ± 0.671
1.641AspCys: 1.641 ± 0.443
1.641AspAsp: 1.641 ± 0.897
1.094AspGlu: 1.094 ± 0.573
0.821AspPhe: 0.821 ± 0.557
1.915AspGly: 1.915 ± 0.68
0.547AspHis: 0.547 ± 0.392
4.65AspIle: 4.65 ± 0.736
2.735AspLys: 2.735 ± 0.634
3.282AspLeu: 3.282 ± 1.059
0.0AspMet: 0.0 ± 0.0
1.368AspAsn: 1.368 ± 0.562
4.103AspPro: 4.103 ± 0.965
1.915AspGln: 1.915 ± 0.434
2.462AspArg: 2.462 ± 0.576
3.282AspSer: 3.282 ± 0.976
2.735AspThr: 2.735 ± 0.595
1.094AspVal: 1.094 ± 0.357
1.368AspTrp: 1.368 ± 0.746
1.368AspTyr: 1.368 ± 0.313
0.0AspXaa: 0.0 ± 0.0
Glu
4.376GluAla: 4.376 ± 1.009
0.274GluCys: 0.274 ± 0.257
3.556GluAsp: 3.556 ± 1.416
7.659GluGlu: 7.659 ± 1.219
1.368GluPhe: 1.368 ± 0.531
4.103GluGly: 4.103 ± 1.387
1.641GluHis: 1.641 ± 0.644
2.735GluIle: 2.735 ± 0.538
4.376GluLys: 4.376 ± 0.946
4.376GluLeu: 4.376 ± 1.119
1.368GluMet: 1.368 ± 0.451
2.735GluAsn: 2.735 ± 0.602
2.735GluPro: 2.735 ± 0.675
3.282GluGln: 3.282 ± 0.69
3.556GluArg: 3.556 ± 1.326
1.641GluSer: 1.641 ± 0.559
6.291GluThr: 6.291 ± 1.237
3.556GluVal: 3.556 ± 0.375
1.915GluTrp: 1.915 ± 0.426
1.641GluTyr: 1.641 ± 0.923
0.0GluXaa: 0.0 ± 0.0
Phe
1.368PheAla: 1.368 ± 0.27
1.094PheCys: 1.094 ± 0.493
0.821PheAsp: 0.821 ± 0.562
0.274PheGlu: 0.274 ± 0.257
1.094PhePhe: 1.094 ± 0.469
0.821PheGly: 0.821 ± 0.49
0.274PheHis: 0.274 ± 0.326
1.368PheIle: 1.368 ± 0.509
1.368PheLys: 1.368 ± 0.798
1.915PheLeu: 1.915 ± 0.413
0.274PheMet: 0.274 ± 0.186
3.009PheAsn: 3.009 ± 0.859
1.094PhePro: 1.094 ± 0.863
1.641PheGln: 1.641 ± 0.653
2.462PheArg: 2.462 ± 0.782
2.462PheSer: 2.462 ± 0.784
2.462PheThr: 2.462 ± 0.976
0.821PheVal: 0.821 ± 0.233
0.547PheTrp: 0.547 ± 0.219
1.915PheTyr: 1.915 ± 0.774
0.0PheXaa: 0.0 ± 0.0
Gly
5.744GlyAla: 5.744 ± 1.537
2.462GlyCys: 2.462 ± 0.772
3.009GlyAsp: 3.009 ± 0.528
4.65GlyGlu: 4.65 ± 1.28
2.735GlyPhe: 2.735 ± 0.637
6.838GlyGly: 6.838 ± 1.026
1.641GlyHis: 1.641 ± 0.778
6.565GlyIle: 6.565 ± 2.063
4.376GlyLys: 4.376 ± 1.04
5.744GlyLeu: 5.744 ± 0.989
1.368GlyMet: 1.368 ± 0.313
3.282GlyAsn: 3.282 ± 0.64
4.103GlyPro: 4.103 ± 0.963
4.376GlyGln: 4.376 ± 1.05
4.65GlyArg: 4.65 ± 1.37
4.65GlySer: 4.65 ± 1.087
3.009GlyThr: 3.009 ± 0.941
6.018GlyVal: 6.018 ± 0.992
0.821GlyTrp: 0.821 ± 0.347
1.094GlyTyr: 1.094 ± 0.353
0.0GlyXaa: 0.0 ± 0.0
His
1.094HisAla: 1.094 ± 0.568
0.547HisCys: 0.547 ± 0.4
0.274HisAsp: 0.274 ± 0.186
0.274HisGlu: 0.274 ± 0.186
0.547HisPhe: 0.547 ± 0.488
1.915HisGly: 1.915 ± 0.573
0.547HisHis: 0.547 ± 0.642
1.915HisIle: 1.915 ± 0.788
0.821HisLys: 0.821 ± 0.347
2.462HisLeu: 2.462 ± 0.676
0.274HisMet: 0.274 ± 0.323
1.641HisAsn: 1.641 ± 0.75
2.462HisPro: 2.462 ± 0.939
2.188HisGln: 2.188 ± 0.942
1.094HisArg: 1.094 ± 0.617
1.915HisSer: 1.915 ± 0.963
2.188HisThr: 2.188 ± 0.643
0.274HisVal: 0.274 ± 0.186
0.274HisTrp: 0.274 ± 0.257
0.821HisTyr: 0.821 ± 0.763
0.0HisXaa: 0.0 ± 0.0
Ile
2.462IleAla: 2.462 ± 0.967
0.821IleCys: 0.821 ± 0.347
1.915IleAsp: 1.915 ± 0.878
3.009IleGlu: 3.009 ± 0.549
1.368IlePhe: 1.368 ± 0.564
5.47IleGly: 5.47 ± 1.611
1.641IleHis: 1.641 ± 0.841
6.018IleIle: 6.018 ± 1.133
5.47IleLys: 5.47 ± 1.08
9.3IleLeu: 9.3 ± 1.474
0.821IleMet: 0.821 ± 0.38
1.915IleAsn: 1.915 ± 0.414
4.103IlePro: 4.103 ± 0.901
2.462IleGln: 2.462 ± 0.867
4.376IleArg: 4.376 ± 0.814
2.462IleSer: 2.462 ± 0.431
2.462IleThr: 2.462 ± 1.278
4.376IleVal: 4.376 ± 1.817
2.188IleTrp: 2.188 ± 0.764
3.009IleTyr: 3.009 ± 0.674
0.0IleXaa: 0.0 ± 0.0
Lys
3.829LysAla: 3.829 ± 0.578
1.641LysCys: 1.641 ± 0.75
1.915LysAsp: 1.915 ± 0.453
5.744LysGlu: 5.744 ± 1.625
0.547LysPhe: 0.547 ± 0.219
6.018LysGly: 6.018 ± 1.462
2.462LysHis: 2.462 ± 0.87
4.65LysIle: 4.65 ± 1.374
4.376LysLys: 4.376 ± 1.063
6.565LysLeu: 6.565 ± 1.693
1.094LysMet: 1.094 ± 0.417
1.915LysAsn: 1.915 ± 0.281
0.547LysPro: 0.547 ± 0.219
4.923LysGln: 4.923 ± 1.193
3.829LysArg: 3.829 ± 0.98
1.641LysSer: 1.641 ± 0.55
3.009LysThr: 3.009 ± 0.887
3.282LysVal: 3.282 ± 1.009
0.821LysTrp: 0.821 ± 0.314
2.735LysTyr: 2.735 ± 0.635
0.0LysXaa: 0.0 ± 0.0
Leu
5.197LeuAla: 5.197 ± 0.991
1.094LeuCys: 1.094 ± 0.573
5.197LeuAsp: 5.197 ± 1.213
4.923LeuGlu: 4.923 ± 0.687
3.009LeuPhe: 3.009 ± 1.082
4.103LeuGly: 4.103 ± 1.068
1.915LeuHis: 1.915 ± 0.93
5.197LeuIle: 5.197 ± 1.475
5.744LeuLys: 5.744 ± 1.628
6.565LeuLeu: 6.565 ± 2.049
0.821LeuMet: 0.821 ± 0.233
4.376LeuAsn: 4.376 ± 0.979
2.735LeuPro: 2.735 ± 1.085
6.838LeuGln: 6.838 ± 1.152
3.282LeuArg: 3.282 ± 0.509
4.103LeuSer: 4.103 ± 1.361
5.47LeuThr: 5.47 ± 1.058
5.47LeuVal: 5.47 ± 0.577
3.009LeuTrp: 3.009 ± 0.595
1.915LeuTyr: 1.915 ± 0.888
0.0LeuXaa: 0.0 ± 0.0
Met
1.641MetAla: 1.641 ± 0.406
0.0MetCys: 0.0 ± 0.0
0.821MetAsp: 0.821 ± 0.557
1.368MetGlu: 1.368 ± 0.464
0.821MetPhe: 0.821 ± 0.233
1.641MetGly: 1.641 ± 0.353
0.0MetHis: 0.0 ± 0.0
0.821MetIle: 0.821 ± 0.511
1.915MetLys: 1.915 ± 0.747
3.009MetLeu: 3.009 ± 1.272
0.274MetMet: 0.274 ± 0.186
1.094MetAsn: 1.094 ± 0.442
0.0MetPro: 0.0 ± 0.0
0.547MetGln: 0.547 ± 0.284
0.821MetArg: 0.821 ± 0.553
0.0MetSer: 0.0 ± 0.0
3.556MetThr: 3.556 ± 0.555
0.547MetVal: 0.547 ± 0.219
0.274MetTrp: 0.274 ± 0.186
0.821MetTyr: 0.821 ± 0.49
0.0MetXaa: 0.0 ± 0.0
Asn
2.462AsnAla: 2.462 ± 0.992
2.735AsnCys: 2.735 ± 0.711
0.274AsnAsp: 0.274 ± 0.315
2.462AsnGlu: 2.462 ± 1.006
3.009AsnPhe: 3.009 ± 0.528
0.821AsnGly: 0.821 ± 0.335
1.368AsnHis: 1.368 ± 0.711
4.103AsnIle: 4.103 ± 1.115
3.282AsnLys: 3.282 ± 0.489
3.829AsnLeu: 3.829 ± 1.987
1.368AsnMet: 1.368 ± 0.307
4.103AsnAsn: 4.103 ± 1.308
3.282AsnPro: 3.282 ± 0.84
1.094AsnGln: 1.094 ± 0.429
1.368AsnArg: 1.368 ± 0.47
3.282AsnSer: 3.282 ± 0.873
6.291AsnThr: 6.291 ± 1.438
2.462AsnVal: 2.462 ± 1.059
1.368AsnTrp: 1.368 ± 0.517
1.094AsnTyr: 1.094 ± 0.68
0.0AsnXaa: 0.0 ± 0.0
Pro
3.009ProAla: 3.009 ± 0.73
0.821ProCys: 0.821 ± 0.588
2.462ProAsp: 2.462 ± 1.043
5.197ProGlu: 5.197 ± 0.744
1.641ProPhe: 1.641 ± 0.356
3.282ProGly: 3.282 ± 1.131
0.821ProHis: 0.821 ± 0.485
3.556ProIle: 3.556 ± 0.994
3.009ProLys: 3.009 ± 1.045
4.65ProLeu: 4.65 ± 0.561
1.641ProMet: 1.641 ± 0.712
1.368ProAsn: 1.368 ± 0.471
3.009ProPro: 3.009 ± 0.833
3.009ProGln: 3.009 ± 0.684
3.556ProArg: 3.556 ± 0.567
3.556ProSer: 3.556 ± 1.139
1.915ProThr: 1.915 ± 0.603
5.744ProVal: 5.744 ± 1.803
0.821ProTrp: 0.821 ± 0.519
1.915ProTyr: 1.915 ± 0.461
0.0ProXaa: 0.0 ± 0.0
Gln
5.744GlnAla: 5.744 ± 0.551
1.094GlnCys: 1.094 ± 0.204
2.188GlnAsp: 2.188 ± 0.785
5.197GlnGlu: 5.197 ± 1.144
0.547GlnPhe: 0.547 ± 0.393
7.112GlnGly: 7.112 ± 1.227
1.368GlnHis: 1.368 ± 0.501
4.103GlnIle: 4.103 ± 1.371
2.188GlnLys: 2.188 ± 1.164
4.376GlnLeu: 4.376 ± 0.895
1.368GlnMet: 1.368 ± 0.846
3.829GlnAsn: 3.829 ± 0.772
3.282GlnPro: 3.282 ± 0.904
3.556GlnGln: 3.556 ± 1.833
2.735GlnArg: 2.735 ± 0.822
1.641GlnSer: 1.641 ± 0.495
1.915GlnThr: 1.915 ± 0.774
4.103GlnVal: 4.103 ± 1.018
1.915GlnTrp: 1.915 ± 0.774
1.094GlnTyr: 1.094 ± 0.619
0.0GlnXaa: 0.0 ± 0.0
Arg
4.376ArgAla: 4.376 ± 1.311
0.547ArgCys: 0.547 ± 0.284
3.829ArgAsp: 3.829 ± 1.342
4.376ArgGlu: 4.376 ± 1.235
1.915ArgPhe: 1.915 ± 0.514
3.282ArgGly: 3.282 ± 0.538
1.368ArgHis: 1.368 ± 0.71
1.915ArgIle: 1.915 ± 0.989
4.65ArgLys: 4.65 ± 1.292
3.829ArgLeu: 3.829 ± 0.671
1.094ArgMet: 1.094 ± 0.332
3.009ArgAsn: 3.009 ± 0.629
3.556ArgPro: 3.556 ± 1.359
4.65ArgGln: 4.65 ± 1.187
4.103ArgArg: 4.103 ± 1.685
1.094ArgSer: 1.094 ± 0.438
3.282ArgThr: 3.282 ± 0.723
2.188ArgVal: 2.188 ± 0.573
2.188ArgTrp: 2.188 ± 0.771
1.641ArgTyr: 1.641 ± 0.831
0.0ArgXaa: 0.0 ± 0.0
Ser
3.556SerAla: 3.556 ± 1.02
0.0SerCys: 0.0 ± 0.0
1.641SerAsp: 1.641 ± 0.314
1.641SerGlu: 1.641 ± 0.694
0.821SerPhe: 0.821 ± 0.772
5.744SerGly: 5.744 ± 2.051
0.821SerHis: 0.821 ± 0.49
3.556SerIle: 3.556 ± 0.909
2.462SerLys: 2.462 ± 0.974
4.65SerLeu: 4.65 ± 2.18
1.368SerMet: 1.368 ± 0.547
1.641SerAsn: 1.641 ± 0.92
3.556SerPro: 3.556 ± 1.042
3.009SerGln: 3.009 ± 0.764
2.735SerArg: 2.735 ± 0.86
4.103SerSer: 4.103 ± 2.118
4.65SerThr: 4.65 ± 0.73
4.103SerVal: 4.103 ± 1.388
0.547SerTrp: 0.547 ± 0.54
0.821SerTyr: 0.821 ± 0.588
0.0SerXaa: 0.0 ± 0.0
Thr
6.018ThrAla: 6.018 ± 1.135
0.821ThrCys: 0.821 ± 0.582
2.462ThrAsp: 2.462 ± 0.59
4.103ThrGlu: 4.103 ± 1.223
1.641ThrPhe: 1.641 ± 0.95
5.197ThrGly: 5.197 ± 0.665
1.915ThrHis: 1.915 ± 0.653
2.735ThrIle: 2.735 ± 0.448
2.188ThrLys: 2.188 ± 0.696
5.744ThrLeu: 5.744 ± 0.815
1.368ThrMet: 1.368 ± 0.645
3.556ThrAsn: 3.556 ± 1.053
6.565ThrPro: 6.565 ± 0.967
2.462ThrGln: 2.462 ± 0.884
2.462ThrArg: 2.462 ± 0.483
4.923ThrSer: 4.923 ± 1.332
6.018ThrThr: 6.018 ± 1.17
3.829ThrVal: 3.829 ± 0.687
3.556ThrTrp: 3.556 ± 0.368
0.821ThrTyr: 0.821 ± 0.44
0.0ThrXaa: 0.0 ± 0.0
Val
2.462ValAla: 2.462 ± 0.471
0.821ValCys: 0.821 ± 0.329
3.282ValAsp: 3.282 ± 1.256
3.556ValGlu: 3.556 ± 0.869
1.094ValPhe: 1.094 ± 0.464
6.018ValGly: 6.018 ± 0.714
1.641ValHis: 1.641 ± 0.381
4.103ValIle: 4.103 ± 1.023
5.197ValLys: 5.197 ± 0.683
4.103ValLeu: 4.103 ± 1.004
0.274ValMet: 0.274 ± 0.186
3.556ValAsn: 3.556 ± 0.996
4.103ValPro: 4.103 ± 0.695
5.47ValGln: 5.47 ± 0.83
3.282ValArg: 3.282 ± 0.537
3.009ValSer: 3.009 ± 0.707
1.915ValThr: 1.915 ± 0.607
4.376ValVal: 4.376 ± 1.214
1.641ValTrp: 1.641 ± 0.652
1.368ValTyr: 1.368 ± 0.646
0.0ValXaa: 0.0 ± 0.0
Trp
2.188TrpAla: 2.188 ± 0.502
0.0TrpCys: 0.0 ± 0.0
1.094TrpAsp: 1.094 ± 0.401
1.915TrpGlu: 1.915 ± 0.446
0.821TrpPhe: 0.821 ± 0.579
1.915TrpGly: 1.915 ± 0.532
0.274TrpHis: 0.274 ± 0.321
1.641TrpIle: 1.641 ± 0.703
2.462TrpLys: 2.462 ± 0.505
0.821TrpLeu: 0.821 ± 0.537
1.915TrpMet: 1.915 ± 0.728
1.094TrpAsn: 1.094 ± 0.663
0.821TrpPro: 0.821 ± 0.462
1.915TrpGln: 1.915 ± 0.482
1.641TrpArg: 1.641 ± 0.684
0.821TrpSer: 0.821 ± 0.44
2.735TrpThr: 2.735 ± 0.887
1.368TrpVal: 1.368 ± 0.546
0.821TrpTrp: 0.821 ± 0.314
0.821TrpTyr: 0.821 ± 0.44
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.547TyrAla: 0.547 ± 0.219
1.641TyrCys: 1.641 ± 0.686
1.368TyrAsp: 1.368 ± 0.353
1.094TyrGlu: 1.094 ± 0.493
1.368TyrPhe: 1.368 ± 0.449
1.094TyrGly: 1.094 ± 0.446
0.547TyrHis: 0.547 ± 0.371
1.368TyrIle: 1.368 ± 0.646
1.368TyrLys: 1.368 ± 0.451
1.368TyrLeu: 1.368 ± 0.309
0.547TyrMet: 0.547 ± 0.219
2.735TyrAsn: 2.735 ± 0.858
1.641TyrPro: 1.641 ± 0.892
1.368TyrGln: 1.368 ± 0.638
1.915TyrArg: 1.915 ± 0.594
1.915TyrSer: 1.915 ± 0.413
2.462TyrThr: 2.462 ± 0.726
1.368TyrVal: 1.368 ± 0.638
0.821TyrTrp: 0.821 ± 0.334
1.641TyrTyr: 1.641 ± 0.657
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (3657 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski