Amino acid dipepetide frequency for Providencia heimbachae ATCC 35613

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.385AlaAla: 7.385 ± 0.091	0.98AlaCys: 0.98 ± 0.03	4.163AlaAsp: 4.163 ± 0.058	4.846AlaGlu: 4.846 ± 0.076	3.357AlaPhe: 3.357 ± 0.054	5.984AlaGly: 5.984 ± 0.089	1.503AlaHis: 1.503 ± 0.035	6.599AlaIle: 6.599 ± 0.08	4.614AlaLys: 4.614 ± 0.068	9.482AlaLeu: 9.482 ± 0.116	2.475AlaMet: 2.475 ± 0.047	3.438AlaAsn: 3.438 ± 0.058	2.844AlaPro: 2.844 ± 0.049	3.789AlaGln: 3.789 ± 0.069	3.646AlaArg: 3.646 ± 0.055	4.866AlaSer: 4.866 ± 0.058	4.312AlaThr: 4.312 ± 0.061	5.523AlaVal: 5.523 ± 0.077	0.984AlaTrp: 0.984 ± 0.03	2.309AlaTyr: 2.309 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.844CysAla: 0.844 ± 0.026	0.141CysCys: 0.141 ± 0.012	0.601CysAsp: 0.601 ± 0.025	0.601CysGlu: 0.601 ± 0.024	0.445CysPhe: 0.445 ± 0.019	0.977CysGly: 0.977 ± 0.03	0.355CysHis: 0.355 ± 0.021	0.699CysIle: 0.699 ± 0.023	0.417CysLys: 0.417 ± 0.019	1.023CysLeu: 1.023 ± 0.029	0.241CysMet: 0.241 ± 0.013	0.353CysAsn: 0.353 ± 0.015	0.494CysPro: 0.494 ± 0.02	0.508CysGln: 0.508 ± 0.019	0.492CysArg: 0.492 ± 0.021	0.685CysSer: 0.685 ± 0.023	0.504CysThr: 0.504 ± 0.019	0.684CysVal: 0.684 ± 0.024	0.175CysTrp: 0.175 ± 0.011	0.377CysTyr: 0.377 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.163AspAla: 4.163 ± 0.061	0.513AspCys: 0.513 ± 0.021	2.818AspAsp: 2.818 ± 0.05	3.673AspGlu: 3.673 ± 0.055	2.318AspPhe: 2.318 ± 0.043	3.376AspGly: 3.376 ± 0.061	0.89AspHis: 0.89 ± 0.035	4.239AspIle: 4.239 ± 0.059	3.359AspLys: 3.359 ± 0.06	4.678AspLeu: 4.678 ± 0.07	1.346AspMet: 1.346 ± 0.035	2.645AspAsn: 2.645 ± 0.053	2.008AspPro: 2.008 ± 0.046	1.498AspGln: 1.498 ± 0.036	2.126AspArg: 2.126 ± 0.045	3.068AspSer: 3.068 ± 0.057	2.456AspThr: 2.456 ± 0.049	3.521AspVal: 3.521 ± 0.053	0.779AspTrp: 0.779 ± 0.03	1.96AspTyr: 1.96 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.503GluAla: 4.503 ± 0.076	0.52GluCys: 0.52 ± 0.021	2.507GluAsp: 2.507 ± 0.053	3.46GluGlu: 3.46 ± 0.069	2.111GluPhe: 2.111 ± 0.048	3.509GluGly: 3.509 ± 0.06	1.367GluHis: 1.367 ± 0.037	4.202GluIle: 4.202 ± 0.068	4.234GluLys: 4.234 ± 0.06	6.398GluLeu: 6.398 ± 0.091	1.71GluMet: 1.71 ± 0.041	3.046GluAsn: 3.046 ± 0.048	1.959GluPro: 1.959 ± 0.045	3.594GluGln: 3.594 ± 0.065	3.181GluArg: 3.181 ± 0.06	3.393GluSer: 3.393 ± 0.061	3.002GluThr: 3.002 ± 0.052	3.654GluVal: 3.654 ± 0.063	0.752GluTrp: 0.752 ± 0.025	1.743GluTyr: 1.743 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.395PheAla: 3.395 ± 0.063	0.526PheCys: 0.526 ± 0.022	2.498PheAsp: 2.498 ± 0.052	2.163PheGlu: 2.163 ± 0.046	1.884PhePhe: 1.884 ± 0.059	3.126PheGly: 3.126 ± 0.054	0.809PheHis: 0.809 ± 0.029	3.366PheIle: 3.366 ± 0.059	1.827PheLys: 1.827 ± 0.039	3.588PheLeu: 3.588 ± 0.074	1.1PheMet: 1.1 ± 0.031	2.2PheAsn: 2.2 ± 0.045	1.51PhePro: 1.51 ± 0.041	1.144PheGln: 1.144 ± 0.03	1.607PheArg: 1.607 ± 0.041	3.585PheSer: 3.585 ± 0.065	2.472PheThr: 2.472 ± 0.051	2.593PheVal: 2.593 ± 0.052	0.57PheTrp: 0.57 ± 0.022	1.446PheTyr: 1.446 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.381GlyAla: 5.381 ± 0.076	0.936GlyCys: 0.936 ± 0.028	3.361GlyAsp: 3.361 ± 0.053	4.052GlyGlu: 4.052 ± 0.062	3.323GlyPhe: 3.323 ± 0.055	4.772GlyGly: 4.772 ± 0.08	1.463GlyHis: 1.463 ± 0.037	5.57GlyIle: 5.57 ± 0.084	4.111GlyLys: 4.111 ± 0.065	6.93GlyLeu: 6.93 ± 0.087	2.058GlyMet: 2.058 ± 0.044	2.803GlyAsn: 2.803 ± 0.064	1.678GlyPro: 1.678 ± 0.04	2.745GlyGln: 2.745 ± 0.049	3.104GlyArg: 3.104 ± 0.057	4.158GlySer: 4.158 ± 0.069	3.553GlyThr: 3.553 ± 0.056	5.014GlyVal: 5.014 ± 0.073	1.066GlyTrp: 1.066 ± 0.031	2.635GlyTyr: 2.635 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	1.482HisAla: 1.482 ± 0.042	0.325HisCys: 0.325 ± 0.016	1.042HisAsp: 1.042 ± 0.032	1.119HisGlu: 1.119 ± 0.03	1.088HisPhe: 1.088 ± 0.027	1.487HisGly: 1.487 ± 0.037	0.61HisHis: 0.61 ± 0.025	1.458HisIle: 1.458 ± 0.036	0.95HisLys: 0.95 ± 0.032	2.078HisLeu: 2.078 ± 0.048	0.506HisMet: 0.506 ± 0.021	0.909HisAsn: 0.909 ± 0.029	1.156HisPro: 1.156 ± 0.032	1.14HisGln: 1.14 ± 0.033	1.018HisArg: 1.018 ± 0.029	1.281HisSer: 1.281 ± 0.035	0.993HisThr: 0.993 ± 0.031	1.18HisVal: 1.18 ± 0.03	0.355HisTrp: 0.355 ± 0.014	0.887HisTyr: 0.887 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.922IleAla: 6.922 ± 0.085	0.817IleCys: 0.817 ± 0.029	4.317IleAsp: 4.317 ± 0.075	4.719IleGlu: 4.719 ± 0.075	2.798IlePhe: 2.798 ± 0.055	5.4IleGly: 5.4 ± 0.085	1.41IleHis: 1.41 ± 0.031	5.178IleIle: 5.178 ± 0.095	3.811IleLys: 3.811 ± 0.057	6.38IleLeu: 6.38 ± 0.1	1.591IleMet: 1.591 ± 0.04	3.786IleAsn: 3.786 ± 0.062	3.291IlePro: 3.291 ± 0.052	2.506IleGln: 2.506 ± 0.048	3.151IleArg: 3.151 ± 0.052	5.087IleSer: 5.087 ± 0.068	4.255IleThr: 4.255 ± 0.069	4.464IleVal: 4.464 ± 0.065	0.734IleTrp: 0.734 ± 0.023	2.06IleTyr: 2.06 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.553LysAla: 4.553 ± 0.083	0.332LysCys: 0.332 ± 0.019	2.719LysAsp: 2.719 ± 0.055	3.454LysGlu: 3.454 ± 0.056	1.544LysPhe: 1.544 ± 0.039	3.53LysGly: 3.53 ± 0.059	1.1LysHis: 1.1 ± 0.028	3.69LysIle: 3.69 ± 0.065	3.446LysLys: 3.446 ± 0.068	5.363LysLeu: 5.363 ± 0.067	1.722LysMet: 1.722 ± 0.039	2.89LysAsn: 2.89 ± 0.054	2.268LysPro: 2.268 ± 0.049	2.945LysGln: 2.945 ± 0.055	2.595LysArg: 2.595 ± 0.054	3.26LysSer: 3.26 ± 0.062	3.032LysThr: 3.032 ± 0.062	3.531LysVal: 3.531 ± 0.05	0.573LysTrp: 0.573 ± 0.022	1.534LysTyr: 1.534 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	9.475LeuAla: 9.475 ± 0.108	1.133LeuCys: 1.133 ± 0.034	5.224LeuAsp: 5.224 ± 0.078	5.425LeuGlu: 5.425 ± 0.085	4.488LeuPhe: 4.488 ± 0.086	6.811LeuGly: 6.811 ± 0.079	1.932LeuHis: 1.932 ± 0.044	7.168LeuIle: 7.168 ± 0.094	5.511LeuLys: 5.511 ± 0.068	11.063LeuLeu: 11.063 ± 0.131	2.779LeuMet: 2.779 ± 0.049	5.008LeuAsn: 5.008 ± 0.074	5.13LeuPro: 5.13 ± 0.066	3.833LeuGln: 3.833 ± 0.058	4.655LeuArg: 4.655 ± 0.072	8.012LeuSer: 8.012 ± 0.088	6.18LeuThr: 6.18 ± 0.082	6.59LeuVal: 6.59 ± 0.089	1.196LeuTrp: 1.196 ± 0.037	2.818LeuTyr: 2.818 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.549MetAla: 2.549 ± 0.05	0.205MetCys: 0.205 ± 0.012	1.196MetAsp: 1.196 ± 0.032	1.277MetGlu: 1.277 ± 0.032	0.893MetPhe: 0.893 ± 0.029	1.877MetGly: 1.877 ± 0.04	0.468MetHis: 0.468 ± 0.018	1.727MetIle: 1.727 ± 0.042	1.669MetLys: 1.669 ± 0.038	2.828MetLeu: 2.828 ± 0.058	0.915MetMet: 0.915 ± 0.03	1.368MetAsn: 1.368 ± 0.033	1.232MetPro: 1.232 ± 0.033	1.156MetGln: 1.156 ± 0.033	1.168MetArg: 1.168 ± 0.036	2.025MetSer: 2.025 ± 0.039	1.701MetThr: 1.701 ± 0.039	1.854MetVal: 1.854 ± 0.042	0.265MetTrp: 0.265 ± 0.017	0.573MetTyr: 0.573 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.517AsnAla: 3.517 ± 0.058	0.439AsnCys: 0.439 ± 0.019	2.357AsnAsp: 2.357 ± 0.047	2.73AsnGlu: 2.73 ± 0.05	1.629AsnPhe: 1.629 ± 0.036	3.206AsnGly: 3.206 ± 0.067	1.074AsnHis: 1.074 ± 0.031	3.571AsnIle: 3.571 ± 0.061	2.784AsnLys: 2.784 ± 0.059	4.238AsnLeu: 4.238 ± 0.066	1.134AsnMet: 1.134 ± 0.029	2.494AsnAsn: 2.494 ± 0.058	2.178AsnPro: 2.178 ± 0.052	2.242AsnGln: 2.242 ± 0.046	2.009AsnArg: 2.009 ± 0.04	2.961AsnSer: 2.961 ± 0.063	2.564AsnThr: 2.564 ± 0.048	2.698AsnVal: 2.698 ± 0.049	0.64AsnTrp: 0.64 ± 0.024	1.633AsnTyr: 1.633 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	3.276ProAla: 3.276 ± 0.061	0.381ProCys: 0.381 ± 0.017	2.369ProAsp: 2.369 ± 0.045	3.379ProGlu: 3.379 ± 0.056	1.875ProPhe: 1.875 ± 0.048	2.32ProGly: 2.32 ± 0.055	0.852ProHis: 0.852 ± 0.029	2.885ProIle: 2.885 ± 0.047	2.06ProLys: 2.06 ± 0.043	4.41ProLeu: 4.41 ± 0.077	1.042ProMet: 1.042 ± 0.03	1.823ProAsn: 1.823 ± 0.038	1.354ProPro: 1.354 ± 0.036	1.731ProGln: 1.731 ± 0.038	1.453ProArg: 1.453 ± 0.038	2.508ProSer: 2.508 ± 0.047	2.255ProThr: 2.255 ± 0.042	3.031ProVal: 3.031 ± 0.058	0.562ProTrp: 0.562 ± 0.021	1.312ProTyr: 1.312 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.926GlnAla: 3.926 ± 0.066	0.4GlnCys: 0.4 ± 0.02	1.912GlnAsp: 1.912 ± 0.04	2.28GlnGlu: 2.28 ± 0.047	1.765GlnPhe: 1.765 ± 0.041	2.961GlnGly: 2.961 ± 0.052	1.091GlnHis: 1.091 ± 0.034	2.823GlnIle: 2.823 ± 0.052	2.455GlnLys: 2.455 ± 0.052	5.159GlnLeu: 5.159 ± 0.091	1.16GlnMet: 1.16 ± 0.033	1.76GlnAsn: 1.76 ± 0.039	1.774GlnPro: 1.774 ± 0.042	3.013GlnGln: 3.013 ± 0.069	2.318GlnArg: 2.318 ± 0.052	2.789GlnSer: 2.789 ± 0.05	2.079GlnThr: 2.079 ± 0.043	2.939GlnVal: 2.939 ± 0.051	0.664GlnTrp: 0.664 ± 0.023	1.493GlnTyr: 1.493 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	3.158ArgAla: 3.158 ± 0.054	0.448ArgCys: 0.448 ± 0.021	2.431ArgAsp: 2.431 ± 0.05	2.997ArgGlu: 2.997 ± 0.057	2.29ArgPhe: 2.29 ± 0.054	2.655ArgGly: 2.655 ± 0.046	1.168ArgHis: 1.168 ± 0.033	3.335ArgIle: 3.335 ± 0.057	2.368ArgLys: 2.368 ± 0.042	5.149ArgLeu: 5.149 ± 0.076	1.252ArgMet: 1.252 ± 0.031	1.959ArgAsn: 1.959 ± 0.041	1.721ArgPro: 1.721 ± 0.037	2.33ArgGln: 2.33 ± 0.048	2.485ArgArg: 2.485 ± 0.053	2.528ArgSer: 2.528 ± 0.051	2.139ArgThr: 2.139 ± 0.041	2.89ArgVal: 2.89 ± 0.052	0.696ArgTrp: 0.696 ± 0.024	1.905ArgTyr: 1.905 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.32SerAla: 5.32 ± 0.078	0.63SerCys: 0.63 ± 0.025	3.281SerAsp: 3.281 ± 0.046	3.746SerGlu: 3.746 ± 0.066	2.736SerPhe: 2.736 ± 0.053	5.084SerGly: 5.084 ± 0.078	1.54SerHis: 1.54 ± 0.037	4.572SerIle: 4.572 ± 0.066	2.965SerLys: 2.965 ± 0.052	7.18SerLeu: 7.18 ± 0.095	1.652SerMet: 1.652 ± 0.034	2.667SerAsn: 2.667 ± 0.051	2.668SerPro: 2.668 ± 0.052	3.068SerGln: 3.068 ± 0.065	3.05SerArg: 3.05 ± 0.054	4.268SerSer: 4.268 ± 0.073	3.442SerThr: 3.442 ± 0.064	4.365SerVal: 4.365 ± 0.058	0.898SerTrp: 0.898 ± 0.027	2.064SerTyr: 2.064 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.378ThrAla: 4.378 ± 0.063	0.539ThrCys: 0.539 ± 0.022	2.765ThrAsp: 2.765 ± 0.054	3.101ThrGlu: 3.101 ± 0.056	2.109ThrPhe: 2.109 ± 0.036	4.08ThrGly: 4.08 ± 0.059	1.208ThrHis: 1.208 ± 0.034	3.7ThrIle: 3.7 ± 0.061	2.323ThrLys: 2.323 ± 0.041	6.506ThrLeu: 6.506 ± 0.077	1.151ThrMet: 1.151 ± 0.033	2.14ThrAsn: 2.14 ± 0.042	2.957ThrPro: 2.957 ± 0.05	2.451ThrGln: 2.451 ± 0.045	2.378ThrArg: 2.378 ± 0.045	3.202ThrSer: 3.202 ± 0.056	2.863ThrThr: 2.863 ± 0.069	3.773ThrVal: 3.773 ± 0.067	0.628ThrTrp: 0.628 ± 0.024	1.506ThrTyr: 1.506 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	5.769ValAla: 5.769 ± 0.082	0.756ValCys: 0.756 ± 0.022	3.592ValAsp: 3.592 ± 0.064	3.758ValGlu: 3.758 ± 0.063	2.61ValPhe: 2.61 ± 0.049	4.524ValGly: 4.524 ± 0.071	1.079ValHis: 1.079 ± 0.031	5.164ValIle: 5.164 ± 0.072	3.384ValLys: 3.384 ± 0.062	6.553ValLeu: 6.553 ± 0.082	2.033ValMet: 2.033 ± 0.042	2.988ValAsn: 2.988 ± 0.047	2.684ValPro: 2.684 ± 0.047	2.101ValGln: 2.101 ± 0.046	2.903ValArg: 2.903 ± 0.052	4.56ValSer: 4.56 ± 0.065	3.93ValThr: 3.93 ± 0.058	4.676ValVal: 4.676 ± 0.078	0.738ValTrp: 0.738 ± 0.026	1.79ValTyr: 1.79 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.83TrpAla: 0.83 ± 0.026	0.16TrpCys: 0.16 ± 0.01	0.651TrpAsp: 0.651 ± 0.022	0.58TrpGlu: 0.58 ± 0.026	0.609TrpPhe: 0.609 ± 0.025	0.815TrpGly: 0.815 ± 0.028	0.327TrpHis: 0.327 ± 0.016	0.777TrpIle: 0.777 ± 0.029	0.539TrpLys: 0.539 ± 0.021	1.925TrpLeu: 1.925 ± 0.045	0.404TrpMet: 0.404 ± 0.022	0.515TrpAsn: 0.515 ± 0.02	0.478TrpPro: 0.478 ± 0.02	0.943TrpGln: 0.943 ± 0.03	0.71TrpArg: 0.71 ± 0.024	0.776TrpSer: 0.776 ± 0.025	0.484TrpThr: 0.484 ± 0.021	0.88TrpVal: 0.88 ± 0.028	0.193TrpTrp: 0.193 ± 0.014	0.372TrpTyr: 0.372 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.271TyrAla: 2.271 ± 0.04	0.437TyrCys: 0.437 ± 0.018	1.63TyrAsp: 1.63 ± 0.039	1.485TyrGlu: 1.485 ± 0.036	1.539TyrPhe: 1.539 ± 0.033	2.218TyrGly: 2.218 ± 0.043	0.817TyrHis: 0.817 ± 0.025	1.954TyrIle: 1.954 ± 0.044	1.256TyrLys: 1.256 ± 0.032	3.499TyrLeu: 3.499 ± 0.056	0.674TyrMet: 0.674 ± 0.021	1.308TyrAsn: 1.308 ± 0.038	1.495TyrPro: 1.495 ± 0.038	2.022TyrGln: 2.022 ± 0.044	1.855TyrArg: 1.855 ± 0.045	2.183TyrSer: 2.183 ± 0.052	1.545TyrThr: 1.545 ± 0.033	1.729TyrVal: 1.729 ± 0.04	0.502TyrTrp: 0.502 ± 0.022	1.121TyrTyr: 1.121 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3766 proteins (1184252 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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