Amino acid dipepetide frequency for Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.513AlaAla: 19.513 ± 0.214	1.441AlaCys: 1.441 ± 0.032	7.111AlaAsp: 7.111 ± 0.078	6.584AlaGlu: 6.584 ± 0.077	3.878AlaPhe: 3.878 ± 0.053	12.235AlaGly: 12.235 ± 0.134	2.742AlaHis: 2.742 ± 0.045	5.457AlaIle: 5.457 ± 0.067	3.007AlaLys: 3.007 ± 0.057	15.102AlaLeu: 15.102 ± 0.137	3.608AlaMet: 3.608 ± 0.046	2.676AlaAsn: 2.676 ± 0.038	6.484AlaPro: 6.484 ± 0.087	6.029AlaGln: 6.029 ± 0.075	10.572AlaArg: 10.572 ± 0.1	6.551AlaSer: 6.551 ± 0.068	5.932AlaThr: 5.932 ± 0.067	9.067AlaVal: 9.067 ± 0.085	2.119AlaTrp: 2.119 ± 0.041	2.819AlaTyr: 2.819 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.329CysAla: 1.329 ± 0.032	0.143CysCys: 0.143 ± 0.009	0.548CysAsp: 0.548 ± 0.017	0.444CysGlu: 0.444 ± 0.015	0.306CysPhe: 0.306 ± 0.014	1.017CysGly: 1.017 ± 0.027	0.279CysHis: 0.279 ± 0.014	0.409CysIle: 0.409 ± 0.018	0.196CysLys: 0.196 ± 0.012	0.94CysLeu: 0.94 ± 0.023	0.224CysMet: 0.224 ± 0.013	0.238CysAsn: 0.238 ± 0.013	0.521CysPro: 0.521 ± 0.019	0.293CysGln: 0.293 ± 0.014	0.694CysArg: 0.694 ± 0.023	0.457CysSer: 0.457 ± 0.018	0.473CysThr: 0.473 ± 0.018	0.791CysVal: 0.791 ± 0.028	0.145CysTrp: 0.145 ± 0.01	0.231CysTyr: 0.231 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.297AspAla: 7.297 ± 0.083	0.47AspCys: 0.47 ± 0.017	3.001AspAsp: 3.001 ± 0.048	3.072AspGlu: 3.072 ± 0.045	1.964AspPhe: 1.964 ± 0.039	4.864AspGly: 4.864 ± 0.062	1.03AspHis: 1.03 ± 0.025	2.697AspIle: 2.697 ± 0.038	1.445AspLys: 1.445 ± 0.038	5.551AspLeu: 5.551 ± 0.075	1.296AspMet: 1.296 ± 0.026	1.215AspAsn: 1.215 ± 0.026	3.189AspPro: 3.189 ± 0.044	1.763AspGln: 1.763 ± 0.034	3.415AspArg: 3.415 ± 0.046	2.412AspSer: 2.412 ± 0.045	2.898AspThr: 2.898 ± 0.049	3.912AspVal: 3.912 ± 0.055	0.973AspTrp: 0.973 ± 0.028	1.445AspTyr: 1.445 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	6.221GluAla: 6.221 ± 0.073	0.406GluCys: 0.406 ± 0.018	2.069GluAsp: 2.069 ± 0.038	2.017GluGlu: 2.017 ± 0.049	1.699GluPhe: 1.699 ± 0.036	3.284GluGly: 3.284 ± 0.053	1.379GluHis: 1.379 ± 0.036	2.648GluIle: 2.648 ± 0.047	1.581GluLys: 1.581 ± 0.047	5.664GluLeu: 5.664 ± 0.07	1.134GluMet: 1.134 ± 0.029	1.325GluAsn: 1.325 ± 0.032	2.689GluPro: 2.689 ± 0.051	2.661GluGln: 2.661 ± 0.047	4.466GluArg: 4.466 ± 0.064	2.527GluSer: 2.527 ± 0.039	2.385GluThr: 2.385 ± 0.041	3.491GluVal: 3.491 ± 0.044	0.661GluTrp: 0.661 ± 0.019	1.167GluTyr: 1.167 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	3.867PheAla: 3.867 ± 0.057	0.372PheCys: 0.372 ± 0.012	2.254PheAsp: 2.254 ± 0.045	1.805PheGlu: 1.805 ± 0.034	1.209PhePhe: 1.209 ± 0.033	3.218PheGly: 3.218 ± 0.045	0.706PheHis: 0.706 ± 0.021	1.478PheIle: 1.478 ± 0.032	0.962PheLys: 0.962 ± 0.032	3.004PheLeu: 3.004 ± 0.049	0.784PheMet: 0.784 ± 0.022	0.981PheAsn: 0.981 ± 0.026	1.499PhePro: 1.499 ± 0.034	1.111PheGln: 1.111 ± 0.023	1.925PheArg: 1.925 ± 0.041	2.084PheSer: 2.084 ± 0.041	1.735PheThr: 1.735 ± 0.031	2.457PheVal: 2.457 ± 0.046	0.513PheTrp: 0.513 ± 0.02	0.865PheTyr: 0.865 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.778GlyAla: 9.778 ± 0.098	0.908GlyCys: 0.908 ± 0.028	3.995GlyAsp: 3.995 ± 0.062	4.078GlyGlu: 4.078 ± 0.052	3.012GlyPhe: 3.012 ± 0.044	7.113GlyGly: 7.113 ± 0.144	1.925GlyHis: 1.925 ± 0.037	4.233GlyIle: 4.233 ± 0.06	3.115GlyLys: 3.115 ± 0.047	9.401GlyLeu: 9.401 ± 0.102	2.519GlyMet: 2.519 ± 0.043	2.141GlyAsn: 2.141 ± 0.042	3.401GlyPro: 3.401 ± 0.048	3.741GlyGln: 3.741 ± 0.049	5.907GlyArg: 5.907 ± 0.074	4.465GlySer: 4.465 ± 0.06	4.293GlyThr: 4.293 ± 0.058	6.553GlyVal: 6.553 ± 0.078	1.468GlyTrp: 1.468 ± 0.03	2.565GlyTyr: 2.565 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	3.051HisAla: 3.051 ± 0.053	0.273HisCys: 0.273 ± 0.013	1.288HisAsp: 1.288 ± 0.032	1.104HisGlu: 1.104 ± 0.03	0.787HisPhe: 0.787 ± 0.023	2.167HisGly: 2.167 ± 0.044	0.586HisHis: 0.586 ± 0.023	0.996HisIle: 0.996 ± 0.026	0.54HisLys: 0.54 ± 0.019	2.174HisLeu: 2.174 ± 0.035	0.512HisMet: 0.512 ± 0.018	0.494HisAsn: 0.494 ± 0.019	1.513HisPro: 1.513 ± 0.029	0.738HisGln: 0.738 ± 0.02	1.536HisArg: 1.536 ± 0.036	0.996HisSer: 0.996 ± 0.024	1.104HisThr: 1.104 ± 0.026	1.586HisVal: 1.586 ± 0.032	0.403HisTrp: 0.403 ± 0.017	0.66HisTyr: 0.66 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.867IleAla: 5.867 ± 0.069	0.432IleCys: 0.432 ± 0.017	3.135IleAsp: 3.135 ± 0.055	2.992IleGlu: 2.992 ± 0.042	1.264IlePhe: 1.264 ± 0.032	4.162IleGly: 4.162 ± 0.063	0.852IleHis: 0.852 ± 0.023	1.742IleIle: 1.742 ± 0.037	1.342IleLys: 1.342 ± 0.036	3.724IleLeu: 3.724 ± 0.051	0.909IleMet: 0.909 ± 0.025	1.335IleAsn: 1.335 ± 0.032	2.122IlePro: 2.122 ± 0.04	1.411IleGln: 1.411 ± 0.039	2.762IleArg: 2.762 ± 0.044	2.423IleSer: 2.423 ± 0.045	2.358IleThr: 2.358 ± 0.04	3.724IleVal: 3.724 ± 0.057	0.534IleTrp: 0.534 ± 0.019	1.033IleTyr: 1.033 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.303LysAla: 3.303 ± 0.062	0.152LysCys: 0.152 ± 0.01	1.299LysAsp: 1.299 ± 0.033	1.243LysGlu: 1.243 ± 0.033	0.787LysPhe: 0.787 ± 0.028	1.975LysGly: 1.975 ± 0.045	0.631LysHis: 0.631 ± 0.019	1.251LysIle: 1.251 ± 0.035	1.104LysLys: 1.104 ± 0.044	3.129LysLeu: 3.129 ± 0.047	0.705LysMet: 0.705 ± 0.021	0.732LysAsn: 0.732 ± 0.024	1.781LysPro: 1.781 ± 0.045	1.227LysGln: 1.227 ± 0.029	2.016LysArg: 2.016 ± 0.037	1.526LysSer: 1.526 ± 0.034	1.665LysThr: 1.665 ± 0.04	2.143LysVal: 2.143 ± 0.039	0.377LysTrp: 0.377 ± 0.016	0.639LysTyr: 0.639 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	16.467LeuAla: 16.467 ± 0.149	1.11LeuCys: 1.11 ± 0.025	6.361LeuAsp: 6.361 ± 0.069	4.914LeuGlu: 4.914 ± 0.06	3.442LeuPhe: 3.442 ± 0.055	8.858LeuGly: 8.858 ± 0.091	2.262LeuHis: 2.262 ± 0.049	4.352LeuIle: 4.352 ± 0.062	3.031LeuLys: 3.031 ± 0.05	11.267LeuLeu: 11.267 ± 0.125	2.377LeuMet: 2.377 ± 0.038	2.724LeuAsn: 2.724 ± 0.044	6.388LeuPro: 6.388 ± 0.073	4.079LeuGln: 4.079 ± 0.052	8.23LeuArg: 8.23 ± 0.084	5.936LeuSer: 5.936 ± 0.066	5.22LeuThr: 5.22 ± 0.057	7.657LeuVal: 7.657 ± 0.072	1.284LeuTrp: 1.284 ± 0.036	2.386LeuTyr: 2.386 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.206MetAla: 3.206 ± 0.044	0.189MetCys: 0.189 ± 0.01	1.039MetAsp: 1.039 ± 0.025	0.963MetGlu: 0.963 ± 0.023	0.709MetPhe: 0.709 ± 0.023	1.822MetGly: 1.822 ± 0.03	0.544MetHis: 0.544 ± 0.018	0.944MetIle: 0.944 ± 0.025	0.884MetLys: 0.884 ± 0.028	2.842MetLeu: 2.842 ± 0.045	0.584MetMet: 0.584 ± 0.023	0.776MetAsn: 0.776 ± 0.018	1.636MetPro: 1.636 ± 0.029	1.156MetGln: 1.156 ± 0.032	1.806MetArg: 1.806 ± 0.034	1.659MetSer: 1.659 ± 0.032	1.523MetThr: 1.523 ± 0.03	1.642MetVal: 1.642 ± 0.033	0.2MetTrp: 0.2 ± 0.013	0.424MetTyr: 0.424 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.982AsnAla: 2.982 ± 0.053	0.223AsnCys: 0.223 ± 0.012	1.246AsnAsp: 1.246 ± 0.028	1.132AsnGlu: 1.132 ± 0.028	0.836AsnPhe: 0.836 ± 0.026	2.111AsnGly: 2.111 ± 0.044	0.468AsnHis: 0.468 ± 0.018	1.243AsnIle: 1.243 ± 0.028	0.721AsnLys: 0.721 ± 0.023	2.612AsnLeu: 2.612 ± 0.043	0.583AsnMet: 0.583 ± 0.02	0.712AsnAsn: 0.712 ± 0.024	1.771AsnPro: 1.771 ± 0.034	0.886AsnGln: 0.886 ± 0.024	1.698AsnArg: 1.698 ± 0.034	1.157AsnSer: 1.157 ± 0.035	1.358AsnThr: 1.358 ± 0.032	1.878AsnVal: 1.878 ± 0.041	0.409AsnTrp: 0.409 ± 0.014	0.655AsnTyr: 0.655 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	8.193ProAla: 8.193 ± 0.102	0.414ProCys: 0.414 ± 0.017	3.727ProAsp: 3.727 ± 0.057	3.259ProGlu: 3.259 ± 0.051	1.746ProPhe: 1.746 ± 0.033	5.05ProGly: 5.05 ± 0.063	1.258ProHis: 1.258 ± 0.029	1.949ProIle: 1.949 ± 0.035	1.228ProLys: 1.228 ± 0.031	5.366ProLeu: 5.366 ± 0.069	1.356ProMet: 1.356 ± 0.031	1.212ProAsn: 1.212 ± 0.027	2.895ProPro: 2.895 ± 0.059	2.183ProGln: 2.183 ± 0.041	3.422ProArg: 3.422 ± 0.051	2.713ProSer: 2.713 ± 0.042	2.395ProThr: 2.395 ± 0.033	4.41ProVal: 4.41 ± 0.061	0.817ProTrp: 0.817 ± 0.023	1.389ProTyr: 1.389 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	6.864GlnAla: 6.864 ± 0.089	0.326GlnCys: 0.326 ± 0.013	1.89GlnAsp: 1.89 ± 0.038	1.789GlnGlu: 1.789 ± 0.038	1.226GlnPhe: 1.226 ± 0.027	3.328GlnGly: 3.328 ± 0.045	0.97GlnHis: 0.97 ± 0.025	1.774GlnIle: 1.774 ± 0.037	0.969GlnLys: 0.969 ± 0.026	3.88GlnLeu: 3.88 ± 0.051	0.937GlnMet: 0.937 ± 0.025	0.801GlnAsn: 0.801 ± 0.021	2.529GlnPro: 2.529 ± 0.049	1.969GlnGln: 1.969 ± 0.042	3.525GlnArg: 3.525 ± 0.052	1.9GlnSer: 1.9 ± 0.041	1.826GlnThr: 1.826 ± 0.035	3.126GlnVal: 3.126 ± 0.047	0.691GlnTrp: 0.691 ± 0.021	0.903GlnTyr: 0.903 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.918ArgAla: 8.918 ± 0.095	0.687ArgCys: 0.687 ± 0.023	3.981ArgAsp: 3.981 ± 0.057	4.035ArgGlu: 4.035 ± 0.056	2.413ArgPhe: 2.413 ± 0.036	5.108ArgGly: 5.108 ± 0.06	2.16ArgHis: 2.16 ± 0.042	3.702ArgIle: 3.702 ± 0.049	2.076ArgLys: 2.076 ± 0.038	8.438ArgLeu: 8.438 ± 0.085	1.931ArgMet: 1.931 ± 0.034	1.891ArgAsn: 1.891 ± 0.036	3.773ArgPro: 3.773 ± 0.053	3.621ArgGln: 3.621 ± 0.055	6.085ArgArg: 6.085 ± 0.084	3.337ArgSer: 3.337 ± 0.053	3.194ArgThr: 3.194 ± 0.046	5.246ArgVal: 5.246 ± 0.059	1.122ArgTrp: 1.122 ± 0.03	2.285ArgTyr: 2.285 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.205SerAla: 6.205 ± 0.07	0.485SerCys: 0.485 ± 0.017	2.497SerAsp: 2.497 ± 0.047	2.291SerGlu: 2.291 ± 0.038	1.884SerPhe: 1.884 ± 0.04	5.068SerGly: 5.068 ± 0.072	1.203SerHis: 1.203 ± 0.028	2.344SerIle: 2.344 ± 0.042	1.334SerLys: 1.334 ± 0.033	5.721SerLeu: 5.721 ± 0.066	1.412SerMet: 1.412 ± 0.032	1.321SerAsn: 1.321 ± 0.029	2.808SerPro: 2.808 ± 0.041	1.917SerGln: 1.917 ± 0.038	3.643SerArg: 3.643 ± 0.052	2.913SerSer: 2.913 ± 0.057	2.695SerThr: 2.695 ± 0.047	3.907SerVal: 3.907 ± 0.049	0.742SerTrp: 0.742 ± 0.024	1.259SerTyr: 1.259 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	5.738ThrAla: 5.738 ± 0.058	0.438ThrCys: 0.438 ± 0.016	2.5ThrAsp: 2.5 ± 0.045	2.255ThrGlu: 2.255 ± 0.039	1.546ThrPhe: 1.546 ± 0.036	4.473ThrGly: 4.473 ± 0.066	1.132ThrHis: 1.132 ± 0.03	2.126ThrIle: 2.126 ± 0.042	0.978ThrLys: 0.978 ± 0.023	6.388ThrLeu: 6.388 ± 0.068	1.052ThrMet: 1.052 ± 0.027	1.041ThrAsn: 1.041 ± 0.029	3.531ThrPro: 3.531 ± 0.055	1.799ThrGln: 1.799 ± 0.029	3.543ThrArg: 3.543 ± 0.047	2.449ThrSer: 2.449 ± 0.048	2.45ThrThr: 2.45 ± 0.049	3.998ThrVal: 3.998 ± 0.051	0.686ThrTrp: 0.686 ± 0.022	1.095ThrTyr: 1.095 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	9.702ValAla: 9.702 ± 0.096	0.76ValCys: 0.76 ± 0.024	3.906ValAsp: 3.906 ± 0.051	3.768ValGlu: 3.768 ± 0.056	2.66ValPhe: 2.66 ± 0.043	5.545ValGly: 5.545 ± 0.073	1.514ValHis: 1.514 ± 0.034	3.239ValIle: 3.239 ± 0.049	2.08ValLys: 2.08 ± 0.045	8.345ValLeu: 8.345 ± 0.083	1.742ValMet: 1.742 ± 0.033	1.977ValAsn: 1.977 ± 0.039	4.293ValPro: 4.293 ± 0.059	2.855ValGln: 2.855 ± 0.043	5.401ValArg: 5.401 ± 0.061	4.16ValSer: 4.16 ± 0.05	3.723ValThr: 3.723 ± 0.061	6.072ValVal: 6.072 ± 0.085	0.922ValTrp: 0.922 ± 0.025	1.696ValTyr: 1.696 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.364TrpAla: 1.364 ± 0.029	0.163TrpCys: 0.163 ± 0.01	0.591TrpAsp: 0.591 ± 0.02	0.546TrpGlu: 0.546 ± 0.019	0.539TrpPhe: 0.539 ± 0.019	0.956TrpGly: 0.956 ± 0.023	0.408TrpHis: 0.408 ± 0.013	0.662TrpIle: 0.662 ± 0.023	0.445TrpLys: 0.445 ± 0.018	2.195TrpLeu: 2.195 ± 0.045	0.412TrpMet: 0.412 ± 0.016	0.464TrpAsn: 0.464 ± 0.018	0.792TrpPro: 0.792 ± 0.024	0.84TrpGln: 0.84 ± 0.022	1.37TrpArg: 1.37 ± 0.035	0.75TrpSer: 0.75 ± 0.025	0.683TrpThr: 0.683 ± 0.019	0.962TrpVal: 0.962 ± 0.024	0.251TrpTrp: 0.251 ± 0.014	0.325TrpTyr: 0.325 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.063TyrAla: 3.063 ± 0.048	0.287TyrCys: 0.287 ± 0.012	1.468TyrAsp: 1.468 ± 0.031	1.182TyrGlu: 1.182 ± 0.032	0.921TyrPhe: 0.921 ± 0.024	2.258TyrGly: 2.258 ± 0.041	0.462TyrHis: 0.462 ± 0.017	0.877TyrIle: 0.877 ± 0.025	0.646TyrLys: 0.646 ± 0.02	2.601TyrLeu: 2.601 ± 0.043	0.469TyrMet: 0.469 ± 0.017	0.627TyrAsn: 0.627 ± 0.021	1.368TyrPro: 1.368 ± 0.031	0.943TyrGln: 0.943 ± 0.024	1.987TyrArg: 1.987 ± 0.037	1.234TyrSer: 1.234 ± 0.028	1.311TyrThr: 1.311 ± 0.026	1.737TyrVal: 1.737 ± 0.036	0.402TyrTrp: 0.402 ± 0.016	0.684TyrTyr: 0.684 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4912 proteins (1563838 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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