Amino acid dipepetide frequency for Dragonfly-associated mastrevirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.052AlaAla: 1.052 ± 0.961
0.0AlaCys: 0.0 ± 0.0
2.103AlaAsp: 2.103 ± 1.007
0.0AlaGlu: 0.0 ± 0.0
1.052AlaPhe: 1.052 ± 1.05
5.258AlaGly: 5.258 ± 1.421
3.155AlaHis: 3.155 ± 0.401
2.103AlaIle: 2.103 ± 0.915
4.206AlaLys: 4.206 ± 0.785
4.206AlaLeu: 4.206 ± 1.998
1.052AlaMet: 1.052 ± 0.877
1.052AlaAsn: 1.052 ± 1.05
4.206AlaPro: 4.206 ± 2.008
4.206AlaGln: 4.206 ± 1.83
4.206AlaArg: 4.206 ± 2.58
4.206AlaSer: 4.206 ± 2.642
8.412AlaThr: 8.412 ± 1.277
1.052AlaVal: 1.052 ± 1.05
2.103AlaTrp: 2.103 ± 2.1
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.103CysAsp: 2.103 ± 0.915
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.052CysGly: 1.052 ± 0.771
0.0CysHis: 0.0 ± 0.0
3.155CysIle: 3.155 ± 1.385
0.0CysLys: 0.0 ± 0.0
2.103CysLeu: 2.103 ± 1.244
1.052CysMet: 1.052 ± 0.771
2.103CysAsn: 2.103 ± 0.915
1.052CysPro: 1.052 ± 0.771
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.103CysVal: 2.103 ± 1.508
1.052CysTrp: 1.052 ± 0.771
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.103AspAla: 2.103 ± 0.915
1.052AspCys: 1.052 ± 1.05
1.052AspAsp: 1.052 ± 0.771
2.103AspGlu: 2.103 ± 0.877
2.103AspPhe: 2.103 ± 1.542
3.155AspGly: 3.155 ± 0.401
0.0AspHis: 0.0 ± 0.0
4.206AspIle: 4.206 ± 0.704
1.052AspLys: 1.052 ± 0.961
5.258AspLeu: 5.258 ± 1.325
1.052AspMet: 1.052 ± 0.961
3.155AspAsn: 3.155 ± 1.385
2.103AspPro: 2.103 ± 0.915
1.052AspGln: 1.052 ± 0.971
0.0AspArg: 0.0 ± 0.0
3.155AspSer: 3.155 ± 2.3
1.052AspThr: 1.052 ± 1.05
2.103AspVal: 2.103 ± 1.921
3.155AspTrp: 3.155 ± 1.385
3.155AspTyr: 3.155 ± 0.401
0.0AspXaa: 0.0 ± 0.0
Glu
1.052GluAla: 1.052 ± 0.961
0.0GluCys: 0.0 ± 0.0
3.155GluAsp: 3.155 ± 1.343
3.155GluGlu: 3.155 ± 1.385
0.0GluPhe: 0.0 ± 0.0
2.103GluGly: 2.103 ± 1.508
0.0GluHis: 0.0 ± 0.0
2.103GluIle: 2.103 ± 0.915
1.052GluLys: 1.052 ± 0.771
3.155GluLeu: 3.155 ± 1.021
0.0GluMet: 0.0 ± 0.667
4.206GluAsn: 4.206 ± 1.83
4.206GluPro: 4.206 ± 1.83
0.0GluGln: 0.0 ± 0.0
1.052GluArg: 1.052 ± 0.971
4.206GluSer: 4.206 ± 1.315
1.052GluThr: 1.052 ± 0.961
3.155GluVal: 3.155 ± 1.722
3.155GluTrp: 3.155 ± 0.401
6.309GluTyr: 6.309 ± 2.745
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
4.206PheCys: 4.206 ± 0.704
3.155PheAsp: 3.155 ± 0.401
8.412PheGlu: 8.412 ± 2.758
1.052PhePhe: 1.052 ± 0.771
2.103PheGly: 2.103 ± 2.1
0.0PheHis: 0.0 ± 0.0
1.052PheIle: 1.052 ± 0.961
2.103PheLys: 2.103 ± 0.877
2.103PheLeu: 2.103 ± 0.915
0.0PheMet: 0.0 ± 0.0
3.155PheAsn: 3.155 ± 1.67
7.361PhePro: 7.361 ± 3.469
0.0PheGln: 0.0 ± 0.0
2.103PheArg: 2.103 ± 0.915
6.309PheSer: 6.309 ± 2.745
3.155PheThr: 3.155 ± 1.313
3.155PheVal: 3.155 ± 1.67
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.309GlyAla: 6.309 ± 2.302
0.0GlyCys: 0.0 ± 0.0
2.103GlyAsp: 2.103 ± 1.508
7.361GlyGlu: 7.361 ± 1.028
2.103GlyPhe: 2.103 ± 1.244
8.412GlyGly: 8.412 ± 4.166
1.052GlyHis: 1.052 ± 0.961
4.206GlyIle: 4.206 ± 1.998
2.103GlyLys: 2.103 ± 1.542
5.258GlyLeu: 5.258 ± 0.744
0.0GlyMet: 0.0 ± 0.0
5.258GlyAsn: 5.258 ± 3.77
3.155GlyPro: 3.155 ± 1.385
2.103GlyGln: 2.103 ± 1.942
5.258GlyArg: 5.258 ± 2.084
7.361GlySer: 7.361 ± 2.701
4.206GlyThr: 4.206 ± 1.153
4.206GlyVal: 4.206 ± 2.21
1.052GlyTrp: 1.052 ± 0.961
1.052GlyTyr: 1.052 ± 0.961
0.0GlyXaa: 0.0 ± 0.0
His
1.052HisAla: 1.052 ± 0.971
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.103HisGlu: 2.103 ± 0.915
3.155HisPhe: 3.155 ± 0.401
3.155HisGly: 3.155 ± 0.401
2.103HisHis: 2.103 ± 0.915
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.103HisLeu: 2.103 ± 0.915
0.0HisMet: 0.0 ± 0.0
1.052HisAsn: 1.052 ± 0.771
3.155HisPro: 3.155 ± 1.722
0.0HisGln: 0.0 ± 0.0
1.052HisArg: 1.052 ± 0.961
2.103HisSer: 2.103 ± 0.915
1.052HisThr: 1.052 ± 0.961
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.155IleAla: 3.155 ± 1.366
3.155IleCys: 3.155 ± 1.385
4.206IleAsp: 4.206 ± 1.754
0.0IleGlu: 0.0 ± 0.0
5.258IlePhe: 5.258 ± 1.036
6.309IleGly: 6.309 ± 0.795
0.0IleHis: 0.0 ± 0.0
5.258IleIle: 5.258 ± 2.218
2.103IleLys: 2.103 ± 0.877
5.258IleLeu: 5.258 ± 2.218
2.103IleMet: 2.103 ± 0.915
1.052IleAsn: 1.052 ± 0.961
2.103IlePro: 2.103 ± 1.542
7.361IleGln: 7.361 ± 1.913
4.206IleArg: 4.206 ± 1.83
5.258IleSer: 5.258 ± 1.036
3.155IleThr: 3.155 ± 0.401
1.052IleVal: 1.052 ± 0.961
0.0IleTrp: 0.0 ± 0.0
1.052IleTyr: 1.052 ± 0.771
0.0IleXaa: 0.0 ± 0.0
Lys
2.103LysAla: 2.103 ± 1.14
0.0LysCys: 0.0 ± 0.0
3.155LysAsp: 3.155 ± 1.021
2.103LysGlu: 2.103 ± 0.915
3.155LysPhe: 3.155 ± 1.343
5.258LysGly: 5.258 ± 0.958
0.0LysHis: 0.0 ± 0.0
1.052LysIle: 1.052 ± 0.961
4.206LysLys: 4.206 ± 2.047
7.361LysLeu: 7.361 ± 2.439
3.155LysMet: 3.155 ± 0.401
3.155LysAsn: 3.155 ± 0.401
1.052LysPro: 1.052 ± 0.961
0.0LysGln: 0.0 ± 0.0
7.361LysArg: 7.361 ± 4.677
8.412LysSer: 8.412 ± 1.277
2.103LysThr: 2.103 ± 1.542
1.052LysVal: 1.052 ± 0.961
0.0LysTrp: 0.0 ± 0.0
3.155LysTyr: 3.155 ± 1.385
0.0LysXaa: 0.0 ± 0.0
Leu
3.155LeuAla: 3.155 ± 2.052
1.052LeuCys: 1.052 ± 1.05
3.155LeuAsp: 3.155 ± 0.401
1.052LeuGlu: 1.052 ± 0.961
5.258LeuPhe: 5.258 ± 1.63
7.361LeuGly: 7.361 ± 1.548
5.258LeuHis: 5.258 ± 2.581
4.206LeuIle: 4.206 ± 1.199
2.103LeuLys: 2.103 ± 0.915
7.361LeuLeu: 7.361 ± 2.392
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
2.103LeuPro: 2.103 ± 1.007
4.206LeuGln: 4.206 ± 1.199
2.103LeuArg: 2.103 ± 1.508
7.361LeuSer: 7.361 ± 3.097
6.309LeuThr: 6.309 ± 1.107
3.155LeuVal: 3.155 ± 1.67
1.052LeuTrp: 1.052 ± 0.971
5.258LeuTyr: 5.258 ± 0.958
0.0LeuXaa: 0.0 ± 0.0
Met
1.052MetAla: 1.052 ± 0.961
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.052MetGly: 1.052 ± 0.961
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.052MetLys: 1.052 ± 0.961
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
2.103MetGln: 2.103 ± 0.915
2.103MetArg: 2.103 ± 0.915
4.206MetSer: 4.206 ± 1.315
0.0MetThr: 0.0 ± 0.0
2.103MetVal: 2.103 ± 0.915
0.0MetTrp: 0.0 ± 0.0
1.052MetTyr: 1.052 ± 0.771
0.0MetXaa: 0.0 ± 0.0
Asn
1.052AsnAla: 1.052 ± 0.771
0.0AsnCys: 0.0 ± 0.0
2.103AsnAsp: 2.103 ± 1.14
3.155AsnGlu: 3.155 ± 1.385
1.052AsnPhe: 1.052 ± 0.771
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
11.567AsnIle: 11.567 ± 4.895
1.052AsnLys: 1.052 ± 0.961
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
5.258AsnAsn: 5.258 ± 2.218
6.309AsnPro: 6.309 ± 1.957
2.103AsnGln: 2.103 ± 1.508
2.103AsnArg: 2.103 ± 0.877
1.052AsnSer: 1.052 ± 0.961
5.258AsnThr: 5.258 ± 1.426
3.155AsnVal: 3.155 ± 1.343
1.052AsnTrp: 1.052 ± 0.961
3.155AsnTyr: 3.155 ± 1.67
0.0AsnXaa: 0.0 ± 0.0
Pro
6.309ProAla: 6.309 ± 1.979
2.103ProCys: 2.103 ± 1.542
0.0ProAsp: 0.0 ± 0.0
4.206ProGlu: 4.206 ± 1.83
5.258ProPhe: 5.258 ± 2.218
3.155ProGly: 3.155 ± 1.366
1.052ProHis: 1.052 ± 0.971
3.155ProIle: 3.155 ± 0.401
7.361ProLys: 7.361 ± 3.097
2.103ProLeu: 2.103 ± 1.007
0.0ProMet: 0.0 ± 0.0
3.155ProAsn: 3.155 ± 1.385
1.052ProPro: 1.052 ± 1.05
1.052ProGln: 1.052 ± 1.05
5.258ProArg: 5.258 ± 1.036
7.361ProSer: 7.361 ± 2.815
3.155ProThr: 3.155 ± 1.385
2.103ProVal: 2.103 ± 2.1
0.0ProTrp: 0.0 ± 0.0
3.155ProTyr: 3.155 ± 1.021
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.103GlnAsp: 2.103 ± 0.915
2.103GlnGlu: 2.103 ± 1.942
7.361GlnPhe: 7.361 ± 1.913
1.052GlnGly: 1.052 ± 0.971
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.052GlnLys: 1.052 ± 0.771
3.155GlnLeu: 3.155 ± 0.401
1.052GlnMet: 1.052 ± 0.741
3.155GlnAsn: 3.155 ± 1.385
3.155GlnPro: 3.155 ± 1.313
1.052GlnGln: 1.052 ± 0.971
1.052GlnArg: 1.052 ± 1.05
10.515GlnSer: 10.515 ± 4.575
0.0GlnThr: 0.0 ± 0.0
2.103GlnVal: 2.103 ± 1.244
0.0GlnTrp: 0.0 ± 0.0
1.052GlnTyr: 1.052 ± 0.961
0.0GlnXaa: 0.0 ± 0.0
Arg
3.155ArgAla: 3.155 ± 1.021
2.103ArgCys: 2.103 ± 0.915
3.155ArgAsp: 3.155 ± 0.401
2.103ArgGlu: 2.103 ± 0.915
3.155ArgPhe: 3.155 ± 0.401
3.155ArgGly: 3.155 ± 1.67
1.052ArgHis: 1.052 ± 0.961
6.309ArgIle: 6.309 ± 1.377
4.206ArgLys: 4.206 ± 1.83
3.155ArgLeu: 3.155 ± 1.712
0.0ArgMet: 0.0 ± 0.0
2.103ArgAsn: 2.103 ± 0.915
3.155ArgPro: 3.155 ± 2.3
3.155ArgGln: 3.155 ± 0.401
4.206ArgArg: 4.206 ± 3.842
5.258ArgSer: 5.258 ± 0.744
6.309ArgThr: 6.309 ± 2.626
2.103ArgVal: 2.103 ± 1.921
1.052ArgTrp: 1.052 ± 0.961
1.052ArgTyr: 1.052 ± 0.961
0.0ArgXaa: 0.0 ± 0.0
Ser
9.464SerAla: 9.464 ± 2.339
0.0SerCys: 0.0 ± 0.0
5.258SerAsp: 5.258 ± 1.036
1.052SerGlu: 1.052 ± 0.961
5.258SerPhe: 5.258 ± 1.181
8.412SerGly: 8.412 ± 4.166
4.206SerHis: 4.206 ± 1.83
3.155SerIle: 3.155 ± 0.401
8.412SerLys: 8.412 ± 1.277
5.258SerLeu: 5.258 ± 2.218
2.103SerMet: 2.103 ± 0.915
4.206SerAsn: 4.206 ± 0.704
7.361SerPro: 7.361 ± 1.501
5.258SerGln: 5.258 ± 1.421
8.412SerArg: 8.412 ± 2.758
11.567SerSer: 11.567 ± 3.565
5.258SerThr: 5.258 ± 2.145
6.309SerVal: 6.309 ± 1.784
1.052SerTrp: 1.052 ± 0.771
3.155SerTyr: 3.155 ± 1.366
0.0SerXaa: 0.0 ± 0.0
Thr
3.155ThrAla: 3.155 ± 1.021
1.052ThrCys: 1.052 ± 0.771
1.052ThrAsp: 1.052 ± 0.961
4.206ThrGlu: 4.206 ± 0.785
0.0ThrPhe: 0.0 ± 0.0
5.258ThrGly: 5.258 ± 3.517
1.052ThrHis: 1.052 ± 0.961
0.0ThrIle: 0.0 ± 0.0
2.103ThrLys: 2.103 ± 0.915
7.361ThrLeu: 7.361 ± 3.172
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
3.155ThrPro: 3.155 ± 1.021
2.103ThrGln: 2.103 ± 0.915
1.052ThrArg: 1.052 ± 0.771
11.567ThrSer: 11.567 ± 1.587
5.258ThrThr: 5.258 ± 3.77
3.155ThrVal: 3.155 ± 1.313
2.103ThrTrp: 2.103 ± 1.921
8.412ThrTyr: 8.412 ± 2.23
0.0ThrXaa: 0.0 ± 0.0
Val
4.206ValAla: 4.206 ± 3.186
0.0ValCys: 0.0 ± 0.0
2.103ValAsp: 2.103 ± 0.915
1.052ValGlu: 1.052 ± 0.771
2.103ValPhe: 2.103 ± 1.921
4.206ValGly: 4.206 ± 3.186
1.052ValHis: 1.052 ± 0.771
4.206ValIle: 4.206 ± 1.537
4.206ValLys: 4.206 ± 3.016
0.0ValLeu: 0.0 ± 0.0
1.052ValMet: 1.052 ± 0.813
4.206ValAsn: 4.206 ± 1.537
2.103ValPro: 2.103 ± 0.915
0.0ValGln: 0.0 ± 0.0
6.309ValArg: 6.309 ± 0.802
2.103ValSer: 2.103 ± 1.007
4.206ValThr: 4.206 ± 1.859
4.206ValVal: 4.206 ± 2.58
1.052ValTrp: 1.052 ± 0.961
4.206ValTyr: 4.206 ± 2.58
0.0ValXaa: 0.0 ± 0.0
Trp
3.155TrpAla: 3.155 ± 1.385
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
4.206TrpLys: 4.206 ± 1.998
4.206TrpLeu: 4.206 ± 1.153
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.052TrpGln: 1.052 ± 0.771
2.103TrpArg: 2.103 ± 1.508
0.0TrpSer: 0.0 ± 0.0
1.052TrpThr: 1.052 ± 0.961
3.155TrpVal: 3.155 ± 0.401
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.103TyrAla: 2.103 ± 0.915
1.052TyrCys: 1.052 ± 0.971
2.103TyrAsp: 2.103 ± 1.921
0.0TyrGlu: 0.0 ± 0.0
2.103TyrPhe: 2.103 ± 0.877
2.103TyrGly: 2.103 ± 1.14
2.103TyrHis: 2.103 ± 0.915
6.309TyrIle: 6.309 ± 1.377
5.258TyrLys: 5.258 ± 2.084
2.103TyrLeu: 2.103 ± 0.915
1.052TyrMet: 1.052 ± 0.771
3.155TyrAsn: 3.155 ± 1.343
4.206TyrPro: 4.206 ± 1.153
3.155TyrGln: 3.155 ± 1.021
0.0TyrArg: 0.0 ± 0.0
3.155TyrSer: 3.155 ± 0.401
1.052TyrThr: 1.052 ± 0.961
3.155TyrVal: 3.155 ± 0.401
1.052TyrTrp: 1.052 ± 0.771
1.052TyrTyr: 1.052 ± 0.771
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (952 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski