Amino acid dipepetide frequency for Fragaria chiloensis latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.911AlaAla: 4.911 ± 1.567
0.756AlaCys: 0.756 ± 0.516
4.911AlaAsp: 4.911 ± 1.647
4.533AlaGlu: 4.533 ± 1.774
3.4AlaPhe: 3.4 ± 1.317
4.533AlaGly: 4.533 ± 1.3
1.511AlaHis: 1.511 ± 0.765
4.533AlaIle: 4.533 ± 1.102
3.022AlaLys: 3.022 ± 1.209
4.156AlaLeu: 4.156 ± 1.39
1.889AlaMet: 1.889 ± 0.635
2.267AlaAsn: 2.267 ± 1.102
3.4AlaPro: 3.4 ± 1.718
0.378AlaGln: 0.378 ± 0.323
3.022AlaArg: 3.022 ± 1.158
3.4AlaSer: 3.4 ± 1.037
4.156AlaThr: 4.156 ± 1.717
6.045AlaVal: 6.045 ± 1.338
2.267AlaTrp: 2.267 ± 1.072
0.756AlaTyr: 0.756 ± 0.516
0.0AlaXaa: 0.0 ± 0.0
Cys
1.133CysAla: 1.133 ± 0.773
1.133CysCys: 1.133 ± 0.41
2.645CysAsp: 2.645 ± 0.826
1.511CysGlu: 1.511 ± 0.483
1.133CysPhe: 1.133 ± 0.587
2.267CysGly: 2.267 ± 1.025
0.756CysHis: 0.756 ± 0.264
1.133CysIle: 1.133 ± 0.773
0.756CysLys: 0.756 ± 0.499
3.022CysLeu: 3.022 ± 2.369
0.378CysMet: 0.378 ± 0.414
0.378CysAsn: 0.378 ± 0.472
1.511CysPro: 1.511 ± 0.632
0.0CysGln: 0.0 ± 0.0
1.889CysArg: 1.889 ± 1.251
3.778CysSer: 3.778 ± 2.122
1.133CysThr: 1.133 ± 0.773
1.133CysVal: 1.133 ± 0.866
0.0CysTrp: 0.0 ± 0.0
0.756CysTyr: 0.756 ± 0.643
0.0CysXaa: 0.0 ± 0.0
Asp
4.533AspAla: 4.533 ± 0.491
1.133AspCys: 1.133 ± 0.401
5.667AspAsp: 5.667 ± 0.821
4.911AspGlu: 4.911 ± 0.857
4.533AspPhe: 4.533 ± 1.136
3.4AspGly: 3.4 ± 1.452
1.133AspHis: 1.133 ± 0.948
3.778AspIle: 3.778 ± 0.92
4.156AspLys: 4.156 ± 1.025
6.8AspLeu: 6.8 ± 0.972
1.133AspMet: 1.133 ± 0.41
0.378AspAsn: 0.378 ± 0.323
2.645AspPro: 2.645 ± 1.029
0.756AspGln: 0.756 ± 0.643
3.4AspArg: 3.4 ± 1.009
4.533AspSer: 4.533 ± 0.96
2.267AspThr: 2.267 ± 0.765
4.533AspVal: 4.533 ± 1.846
0.756AspTrp: 0.756 ± 0.647
1.133AspTyr: 1.133 ± 0.532
0.0AspXaa: 0.0 ± 0.0
Glu
4.911GluAla: 4.911 ± 0.857
1.889GluCys: 1.889 ± 1.002
3.4GluAsp: 3.4 ± 1.157
1.889GluGlu: 1.889 ± 0.775
2.645GluPhe: 2.645 ± 0.883
2.267GluGly: 2.267 ± 2.004
1.133GluHis: 1.133 ± 0.532
4.911GluIle: 4.911 ± 1.332
3.4GluLys: 3.4 ± 1.037
2.645GluLeu: 2.645 ± 1.029
1.133GluMet: 1.133 ± 0.401
1.511GluAsn: 1.511 ± 0.393
1.511GluPro: 1.511 ± 1.094
1.511GluGln: 1.511 ± 0.483
3.778GluArg: 3.778 ± 1.28
3.4GluSer: 3.4 ± 1.297
2.267GluThr: 2.267 ± 0.736
5.289GluVal: 5.289 ± 1.659
1.511GluTrp: 1.511 ± 0.959
1.133GluTyr: 1.133 ± 0.587
0.0GluXaa: 0.0 ± 0.0
Phe
4.533PheAla: 4.533 ± 0.808
1.511PheCys: 1.511 ± 0.616
4.911PheAsp: 4.911 ± 2.06
1.511PheGlu: 1.511 ± 0.53
2.267PhePhe: 2.267 ± 1.179
1.133PheGly: 1.133 ± 0.773
1.889PheHis: 1.889 ± 1.112
3.022PheIle: 3.022 ± 1.004
3.022PheLys: 3.022 ± 1.225
5.289PheLeu: 5.289 ± 1.667
0.378PheMet: 0.378 ± 0.258
2.645PheAsn: 2.645 ± 0.918
3.022PhePro: 3.022 ± 0.573
2.645PheGln: 2.645 ± 0.406
1.133PheArg: 1.133 ± 0.41
6.045PheSer: 6.045 ± 0.908
3.022PheThr: 3.022 ± 0.986
4.156PheVal: 4.156 ± 0.748
0.0PheTrp: 0.0 ± 0.0
0.378PheTyr: 0.378 ± 0.535
0.0PheXaa: 0.0 ± 0.0
Gly
1.511GlyAla: 1.511 ± 0.659
2.267GlyCys: 2.267 ± 0.801
3.022GlyAsp: 3.022 ± 1.058
2.645GlyGlu: 2.645 ± 0.722
3.022GlyPhe: 3.022 ± 0.896
3.4GlyGly: 3.4 ± 0.989
0.378GlyHis: 0.378 ± 0.323
1.889GlyIle: 1.889 ± 0.775
4.911GlyLys: 4.911 ± 0.713
4.911GlyLeu: 4.911 ± 0.737
2.267GlyMet: 2.267 ± 0.932
1.889GlyAsn: 1.889 ± 0.531
1.889GlyPro: 1.889 ± 0.59
1.133GlyGln: 1.133 ± 0.729
3.022GlyArg: 3.022 ± 0.494
3.022GlySer: 3.022 ± 0.621
3.022GlyThr: 3.022 ± 1.302
5.667GlyVal: 5.667 ± 2.714
0.378GlyTrp: 0.378 ± 0.323
1.889GlyTyr: 1.889 ± 1.223
0.0GlyXaa: 0.0 ± 0.0
His
1.133HisAla: 1.133 ± 0.678
1.889HisCys: 1.889 ± 1.289
1.133HisAsp: 1.133 ± 0.507
1.889HisGlu: 1.889 ± 0.775
0.756HisPhe: 0.756 ± 0.264
0.756HisGly: 0.756 ± 0.264
0.756HisHis: 0.756 ± 0.647
0.756HisIle: 0.756 ± 0.264
0.756HisLys: 0.756 ± 0.51
1.889HisLeu: 1.889 ± 0.575
0.378HisMet: 0.378 ± 0.323
1.511HisAsn: 1.511 ± 0.898
1.511HisPro: 1.511 ± 0.857
0.756HisGln: 0.756 ± 0.647
2.267HisArg: 2.267 ± 0.907
1.511HisSer: 1.511 ± 0.659
1.133HisThr: 1.133 ± 0.773
1.133HisVal: 1.133 ± 0.401
0.0HisTrp: 0.0 ± 0.0
0.378HisTyr: 0.378 ± 0.323
0.0HisXaa: 0.0 ± 0.0
Ile
2.267IleAla: 2.267 ± 0.983
1.889IleCys: 1.889 ± 0.575
6.422IleAsp: 6.422 ± 0.775
3.4IleGlu: 3.4 ± 0.779
3.4IlePhe: 3.4 ± 1.22
3.022IleGly: 3.022 ± 1.061
1.133IleHis: 1.133 ± 0.41
2.645IleIle: 2.645 ± 0.903
1.889IleLys: 1.889 ± 0.64
3.4IleLeu: 3.4 ± 0.691
1.511IleMet: 1.511 ± 0.835
1.889IleAsn: 1.889 ± 1.005
5.667IlePro: 5.667 ± 0.785
1.133IleGln: 1.133 ± 0.587
3.4IleArg: 3.4 ± 1.217
5.289IleSer: 5.289 ± 1.65
1.889IleThr: 1.889 ± 0.874
4.156IleVal: 4.156 ± 0.791
0.378IleTrp: 0.378 ± 0.258
2.645IleTyr: 2.645 ± 0.569
0.0IleXaa: 0.0 ± 0.0
Lys
3.778LysAla: 3.778 ± 1.933
0.378LysCys: 0.378 ± 0.535
1.133LysAsp: 1.133 ± 0.41
1.889LysGlu: 1.889 ± 0.845
4.156LysPhe: 4.156 ± 1.303
3.022LysGly: 3.022 ± 1.155
0.378LysHis: 0.378 ± 0.258
3.022LysIle: 3.022 ± 0.621
4.911LysLys: 4.911 ± 1.787
4.911LysLeu: 4.911 ± 0.976
1.133LysMet: 1.133 ± 0.678
1.889LysAsn: 1.889 ± 0.856
2.645LysPro: 2.645 ± 1.029
1.511LysGln: 1.511 ± 0.659
4.156LysArg: 4.156 ± 1.262
3.4LysSer: 3.4 ± 1.232
2.267LysThr: 2.267 ± 0.635
4.156LysVal: 4.156 ± 0.676
0.756LysTrp: 0.756 ± 0.516
1.511LysTyr: 1.511 ± 0.529
0.0LysXaa: 0.0 ± 0.0
Leu
5.289LeuAla: 5.289 ± 1.468
1.133LeuCys: 1.133 ± 0.464
3.4LeuAsp: 3.4 ± 0.486
4.911LeuGlu: 4.911 ± 1.54
4.156LeuPhe: 4.156 ± 0.973
4.156LeuGly: 4.156 ± 1.139
1.511LeuHis: 1.511 ± 0.976
6.045LeuIle: 6.045 ± 2.241
4.911LeuLys: 4.911 ± 1.178
7.178LeuLeu: 7.178 ± 0.779
3.778LeuMet: 3.778 ± 0.83
3.4LeuAsn: 3.4 ± 1.086
6.045LeuPro: 6.045 ± 2.498
2.645LeuGln: 2.645 ± 0.868
5.289LeuArg: 5.289 ± 1.699
9.445LeuSer: 9.445 ± 2.096
4.911LeuThr: 4.911 ± 0.923
5.667LeuVal: 5.667 ± 0.793
0.0LeuTrp: 0.0 ± 0.0
1.889LeuTyr: 1.889 ± 0.838
0.0LeuXaa: 0.0 ± 0.0
Met
1.889MetAla: 1.889 ± 1.24
1.133MetCys: 1.133 ± 0.827
1.511MetAsp: 1.511 ± 0.539
1.133MetGlu: 1.133 ± 0.41
1.889MetPhe: 1.889 ± 0.882
0.756MetGly: 0.756 ± 0.51
0.0MetHis: 0.0 ± 0.0
1.511MetIle: 1.511 ± 0.757
1.133MetLys: 1.133 ± 0.532
1.511MetLeu: 1.511 ± 0.765
0.0MetMet: 0.0 ± 0.0
1.511MetAsn: 1.511 ± 0.529
1.889MetPro: 1.889 ± 1.112
1.889MetGln: 1.889 ± 0.418
1.511MetArg: 1.511 ± 1.22
3.022MetSer: 3.022 ± 1.119
2.645MetThr: 2.645 ± 0.732
1.511MetVal: 1.511 ± 0.839
0.378MetTrp: 0.378 ± 0.535
0.378MetTyr: 0.378 ± 0.258
0.0MetXaa: 0.0 ± 0.0
Asn
4.533AsnAla: 4.533 ± 1.579
1.133AsnCys: 1.133 ± 0.41
1.511AsnAsp: 1.511 ± 0.529
1.511AsnGlu: 1.511 ± 1.094
1.889AsnPhe: 1.889 ± 0.59
1.511AsnGly: 1.511 ± 0.659
1.511AsnHis: 1.511 ± 0.757
1.511AsnIle: 1.511 ± 1.031
1.511AsnLys: 1.511 ± 0.632
3.022AsnLeu: 3.022 ± 1.627
0.756AsnMet: 0.756 ± 0.264
1.511AsnAsn: 1.511 ± 0.481
2.267AsnPro: 2.267 ± 1.123
0.756AsnGln: 0.756 ± 0.528
2.267AsnArg: 2.267 ± 0.535
2.267AsnSer: 2.267 ± 0.448
3.4AsnThr: 3.4 ± 1.298
4.533AsnVal: 4.533 ± 0.993
0.0AsnTrp: 0.0 ± 0.0
0.378AsnTyr: 0.378 ± 0.258
0.0AsnXaa: 0.0 ± 0.0
Pro
2.645ProAla: 2.645 ± 1.367
0.756ProCys: 0.756 ± 0.51
2.645ProAsp: 2.645 ± 0.587
2.267ProGlu: 2.267 ± 0.58
1.133ProPhe: 1.133 ± 0.532
2.267ProGly: 2.267 ± 0.983
0.756ProHis: 0.756 ± 0.264
4.156ProIle: 4.156 ± 1.71
1.133ProLys: 1.133 ± 0.507
5.289ProLeu: 5.289 ± 1.514
1.511ProMet: 1.511 ± 0.53
3.4ProAsn: 3.4 ± 1.543
1.511ProPro: 1.511 ± 0.632
1.133ProGln: 1.133 ± 0.532
3.778ProArg: 3.778 ± 2.465
5.289ProSer: 5.289 ± 1.894
4.533ProThr: 4.533 ± 1.614
5.289ProVal: 5.289 ± 1.303
0.378ProTrp: 0.378 ± 0.323
1.133ProTyr: 1.133 ± 0.948
0.0ProXaa: 0.0 ± 0.0
Gln
1.511GlnAla: 1.511 ± 0.939
0.756GlnCys: 0.756 ± 0.264
0.756GlnAsp: 0.756 ± 0.516
2.267GlnGlu: 2.267 ± 0.635
1.889GlnPhe: 1.889 ± 0.92
0.378GlnGly: 0.378 ± 0.535
1.133GlnHis: 1.133 ± 0.656
1.889GlnIle: 1.889 ± 0.653
0.378GlnLys: 0.378 ± 0.323
1.889GlnLeu: 1.889 ± 0.775
0.756GlnMet: 0.756 ± 0.74
1.511GlnAsn: 1.511 ± 0.659
0.756GlnPro: 0.756 ± 0.264
1.133GlnGln: 1.133 ± 0.41
2.267GlnArg: 2.267 ± 1.102
2.645GlnSer: 2.645 ± 0.599
0.0GlnThr: 0.0 ± 0.0
1.889GlnVal: 1.889 ± 0.96
0.378GlnTrp: 0.378 ± 0.258
1.133GlnTyr: 1.133 ± 0.532
0.0GlnXaa: 0.0 ± 0.0
Arg
1.511ArgAla: 1.511 ± 1.031
3.4ArgCys: 3.4 ± 1.903
1.889ArgAsp: 1.889 ± 0.698
2.267ArgGlu: 2.267 ± 1.71
4.533ArgPhe: 4.533 ± 1.534
4.156ArgGly: 4.156 ± 1.851
2.645ArgHis: 2.645 ± 1.048
2.645ArgIle: 2.645 ± 1.182
4.156ArgLys: 4.156 ± 0.733
3.778ArgLeu: 3.778 ± 0.917
1.133ArgMet: 1.133 ± 0.445
2.645ArgAsn: 2.645 ± 1.034
3.022ArgPro: 3.022 ± 1.525
1.511ArgGln: 1.511 ± 0.539
5.667ArgArg: 5.667 ± 2.559
7.178ArgSer: 7.178 ± 3.234
4.156ArgThr: 4.156 ± 1.003
4.533ArgVal: 4.533 ± 1.045
1.133ArgTrp: 1.133 ± 0.401
3.022ArgTyr: 3.022 ± 1.033
0.0ArgXaa: 0.0 ± 0.0
Ser
4.911SerAla: 4.911 ± 1.303
2.267SerCys: 2.267 ± 0.555
8.311SerAsp: 8.311 ± 1.968
3.778SerGlu: 3.778 ± 1.137
3.778SerPhe: 3.778 ± 0.844
4.911SerGly: 4.911 ± 3.358
2.645SerHis: 2.645 ± 0.889
4.911SerIle: 4.911 ± 1.331
3.778SerLys: 3.778 ± 1.513
7.556SerLeu: 7.556 ± 1.769
2.267SerMet: 2.267 ± 1.624
1.889SerAsn: 1.889 ± 0.856
1.133SerPro: 1.133 ± 0.41
2.267SerGln: 2.267 ± 0.582
4.911SerArg: 4.911 ± 1.632
12.089SerSer: 12.089 ± 2.431
7.178SerThr: 7.178 ± 0.593
7.556SerVal: 7.556 ± 2.288
1.133SerTrp: 1.133 ± 0.532
2.645SerTyr: 2.645 ± 1.378
0.0SerXaa: 0.0 ± 0.0
Thr
4.533ThrAla: 4.533 ± 2.851
0.378ThrCys: 0.378 ± 0.258
2.267ThrAsp: 2.267 ± 1.358
3.022ThrGlu: 3.022 ± 1.371
2.267ThrPhe: 2.267 ± 0.82
4.156ThrGly: 4.156 ± 1.175
1.511ThrHis: 1.511 ± 1.031
4.156ThrIle: 4.156 ± 0.927
1.889ThrLys: 1.889 ± 0.575
5.667ThrLeu: 5.667 ± 1.516
3.022ThrMet: 3.022 ± 1.348
2.267ThrAsn: 2.267 ± 0.41
1.511ThrPro: 1.511 ± 0.939
1.889ThrGln: 1.889 ± 1.147
3.4ThrArg: 3.4 ± 1.043
6.422ThrSer: 6.422 ± 2.031
1.889ThrThr: 1.889 ± 1.289
4.911ThrVal: 4.911 ± 1.067
0.378ThrTrp: 0.378 ± 0.323
2.645ThrTyr: 2.645 ± 0.826
0.0ThrXaa: 0.0 ± 0.0
Val
5.289ValAla: 5.289 ± 0.639
1.889ValCys: 1.889 ± 1.14
4.911ValAsp: 4.911 ± 0.608
3.778ValGlu: 3.778 ± 1.389
2.645ValPhe: 2.645 ± 0.734
4.533ValGly: 4.533 ± 0.491
0.756ValHis: 0.756 ± 0.51
2.645ValIle: 2.645 ± 0.599
2.645ValLys: 2.645 ± 1.328
8.689ValLeu: 8.689 ± 1.958
2.645ValMet: 2.645 ± 0.587
4.156ValAsn: 4.156 ± 1.089
6.8ValPro: 6.8 ± 1.395
1.511ValGln: 1.511 ± 0.632
6.8ValArg: 6.8 ± 2.947
4.911ValSer: 4.911 ± 0.942
6.045ValThr: 6.045 ± 1.763
6.8ValVal: 6.8 ± 2.04
0.756ValTrp: 0.756 ± 0.596
3.022ValTyr: 3.022 ± 1.087
0.0ValXaa: 0.0 ± 0.0
Trp
1.133TrpAla: 1.133 ± 0.587
0.378TrpCys: 0.378 ± 0.323
0.378TrpAsp: 0.378 ± 0.535
0.756TrpGlu: 0.756 ± 0.804
1.511TrpPhe: 1.511 ± 0.529
0.756TrpGly: 0.756 ± 0.51
0.0TrpHis: 0.0 ± 0.0
0.756TrpIle: 0.756 ± 0.264
1.133TrpLys: 1.133 ± 0.536
0.378TrpLeu: 0.378 ± 0.62
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.378TrpPro: 0.378 ± 0.535
0.0TrpGln: 0.0 ± 0.0
0.378TrpArg: 0.378 ± 0.62
1.133TrpSer: 1.133 ± 0.97
0.756TrpThr: 0.756 ± 0.516
0.378TrpVal: 0.378 ± 0.323
0.378TrpTrp: 0.378 ± 0.323
0.756TrpTyr: 0.756 ± 0.647
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.889TyrAla: 1.889 ± 0.964
0.378TyrCys: 0.378 ± 0.62
0.756TyrAsp: 0.756 ± 0.264
2.267TyrGlu: 2.267 ± 0.858
1.511TyrPhe: 1.511 ± 0.483
0.756TyrGly: 0.756 ± 0.516
0.756TyrHis: 0.756 ± 0.264
1.511TyrIle: 1.511 ± 1.024
1.511TyrLys: 1.511 ± 0.529
3.778TyrLeu: 3.778 ± 1.084
0.756TyrMet: 0.756 ± 0.643
1.133TyrAsn: 1.133 ± 0.464
1.889TyrPro: 1.889 ± 1.138
0.756TyrGln: 0.756 ± 0.516
3.022TyrArg: 3.022 ± 0.761
1.133TyrSer: 1.133 ± 0.773
1.511TyrThr: 1.511 ± 0.652
1.889TyrVal: 1.889 ± 0.874
0.378TyrTrp: 0.378 ± 0.472
0.378TyrTyr: 0.378 ± 0.258
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2648 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski